Invitrogen

CD45 Monoclonal Antibody (30-F11), eFluor™ 506, eBioscience™

Advanced Verification

This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.

96 Published Figures

254 References

View all (407) CD45 antibodies

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CD45 Antibody (69-0451-82) in Flow

Staining of C57Bl/6 bone marrow cells with Anti-Mouse TER-119 PE (Product # 12-5921-82) and 0.25 µg of Rat IgG2b K Isotype Control eFluor® 506 (Product # 69-4031-82) (left) or 0.25 µg of Anti-Mouse CD45 eFluor® 506 (right). Total viable cells were used for analysis.

CD45 Antibody in Immunohistochemistry (IHC)

CD45 Antibody in Immunocytochemistry (ICC/IF)

CD45 Antibody in Immunocytochemistry, Flow Cytometry (ICC/IF, Flow)

CD45 Antibody in Immunohistochemistry (Frozen) (IHC (F))

CD45 Antibody in Immunohistochemistry, Flow Cytometry (IHC, Flow)

CD45 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

Product Image Gallery

CD45 Antibody — Fig. 6 Flow cytometry analysis of TILs in the TME of syngeneic tumors with wild-type ( a ) or mutant ( b ) Trp53 . Mice with established MH-22A or MC38 tumors were treated with 10 mg/kg APG-115 ( a and b ), 10 mg/kg ( a ) or 5 mg/kg ( b ) anti-PD-1 antibody, or the combination as described in the legend of Fig. 4 . The control group was treated with isotype control antibody and APG-115 vehicle (I + V). On day 14, syngeneic tumors were harvested, dissociated into single-cell suspensions, and stained for flow cytometry analysis. Percentages of CD45 + , CD3 + T cells, CD8 + T cells, M1 and M2 macrophages in the tumors under the different treatments were assessed. Data were representative of two ( a ) or three ( b ) independent experiments and shown as dot plots ( n = 5 or 10). **** P < 0.0001, *** P < 0.001, ** P < 0.01, and * P < 0.05, by one-way ANOVA with Bonferroni post-test. I + V indicates isotype control and vehicle of APG-115 {TM}

Product Details

69-0451-82

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

View 38 publications 38 publications

Immunohistochemistry (PFA fixed) (IHC (PFA))

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

View 3 publications 3 publications

Immunocytochemistry (ICC/IF)

View 9 publications 9 publications

Flow Cytometry (Flow)

0.5 µg/test

View 203 publications 203 publications

Product Specifications

Species Reactivity

Mouse

Published species

Human, Mouse

Host/Isotype

Rat / IgG2b, kappa

Recommended Isotype Control

Rat IgG2b kappa Isotype Control (eB149/10H5), eFluor™ 506, eBioscience™

Class

Monoclonal

Type

Antibody

Clone

30-F11

Conjugate

eFluor™ 506 eFluor™ 506 eFluor™ 506

Excitation/Emission Max

419/508 nm View spectra

Form

Liquid

Concentration

0.2 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2

Contains

0.09% sodium azide

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2637147

Product Specific Information

Description: The 30-F11 monoclonal antibody reacts with all isoforms of mouse CD45, also known as Leukocyte Common Antigen (LCA). CD45 is expressed by all hematopoietic cells excluding mature erythrocytes and platelets. The cytoplasmic portion of CD45 has tyrosine phosphatase enzymatic activity and plays an important role in activation of lymphocytes.

Applications Reported: This 30-F11 antibody has been reported for use in flow cytometric analysis.

Applications Tested: This 30-F11 antibody has been tested by flow cytometric analysis of mouse bone marrow cells. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

eFluor® 506 can be excited with the violet laser line (405 nm) and emits at 506 nm. We recommend using a 510/20 band pass filter, or equivalent. Please make sure that your instrument is capable of detecting this fluorochrome.

Excitation: 405 nm; Emission: 506 nm; Laser: Violet Laser.

Filtration: 0.2 µm post-manufacturing filtered.

Target Information

CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains. CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells. CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling and suppresses JAK kinases to regulate cytokine receptor signaling. CD45 is also important in promoting cell survival by modulating integrin-mediated signal transduction pathway, DNA fragmentation during apoptosis and inhibition or upregulation of various immunological functions.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

Product References

Spleen-targeted neoantigen DNA vaccine for personalized immunotherapy of hepatocellular carcinoma.

EMBO molecular medicine

Wu M,Luo Z,Cai Z,Mao Q,Li Z,Li H,Zhang C,Zhang Y,Zhong A,Wu L,Liu X

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Oct 11 00:00:00 EDT 2023

Fibroblastic reticular cells in lymph node potentiate white adipose tissue beiging through neuro-immune crosstalk in male mice.

Nature communications

Cheong LY,Wang B,Wang Q,Jin L,Kwok KHM,Wu X,Shu L,Lin H,Chung SK,Cheng KKY,Hoo RLC,Xu A

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Mar 03 00:00:00 EST 2023

Macrophagic AMPKα1 orchestrates regenerative inflammation induced by glucocorticoids.

EMBO reports

Caratti G,Desgeorges T,Juban G,Stifel U,Fessard A,Koenen M,Caratti B,Théret M,Skurk C,Chazaud B,Tuckermann JP,Mounier R

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Feb 06 00:00:00 EST 2023

Topical Diacerein Decreases Skin and Splenic CD11c⁺ Dendritic Cells in Psoriasis.

International journal of molecular sciences

Brunner SM,Ramspacher A,Rieser C,Leitner J,Heil H,Ablinger M,Tevini J,Wimmer M,Koller A,Piñón Hofbauer J,Felder TK,Bauer JW,Kofler B,Lang R,Wally V

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Feb 21 00:00:00 EST 2023

Toll-like Receptor Signaling-deficient Cells Enhance Antitumor Activity of Cell-based Immunotherapy by Increasing Tumor Homing.

Cancer research communications

Morales-Molina A,Rodriguez-Milla MÁ,Gambera S,Cejalvo T,de Andrés B,Gaspar ML,García-Castro J

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Wed Mar 01 00:00:00 EST 2023

BRCA1 deficiency in mature CD8⁺ T lymphocytes impairs antitumor immunity.

Journal for immunotherapy of cancer

Wu B,Qi L,Chiang HC,Pan H,Zhang X,Greenbaum A,Stark E,Wang LJ,Chen Y,Haddad BR,Clagett D,Isaacs C,Elledge R,Horvath A,Hu Y,Li R

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Feb 01 00:00:00 EST 2023

CD11c⁺ microglia promote white matter repair after ischemic stroke.

Cell death & disease

Jia J,Zheng L,Ye L,Chen J,Shu S,Xu S,Bao X,Xia S,Liu R,Xu Y,Zhang M

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Feb 24 00:00:00 EST 2023

Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2023

Senolytic elimination of Cox2-expressing senescent cells inhibits the growth of premalignant pancreatic lesions.

Gut

Kolodkin-Gal D,Roitman L,Ovadya Y,Azazmeh N,Assouline B,Schlesinger Y,Kalifa R,Horwitz S,Khalatnik Y,Hochner-Ger A,Imam A,Demma JA,Winter E,Benyamini H,Elgavish S,Khatib AA,Meir K,Atlan K,Pikarsky E,Parnas O,Dor Y,Zamir G,Ben-Porath I,Krizhanovsky V

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Tue Feb 01 00:00:00 EST 2022

The ZIP8/SIRT1 axis regulates alveolar progenitor cell renewal in aging and idiopathic pulmonary fibrosis.

The Journal of clinical investigation

Liang J,Huang G,Liu X,Taghavifar F,Liu N,Wang Y,Deng N,Yao C,Xie T,Kulur V,Dai K,Burman A,Rowan SC,Weigt SS,Belperio J,Stripp B,Parks WC,Jiang D,Noble PW

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Jun 01 00:00:00 EDT 2022

Interleukin-10 genetically modified clinical-grade mesenchymal stromal cells markedly reinforced functional recovery after spinal cord injury via directing alternative activation of macrophages.

Cellular & molecular biology letters

Gao T,Huang F,Wang W,Xie Y,Wang B

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Mar 17 00:00:00 EDT 2022

BEX1 is a critical determinant of viral myocarditis.

PLoS pathogens

Martens CR,Dorn LE,Kenney AD,Bansal SS,Yount JS,Accornero F

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Feb 01 00:00:00 EST 2022

Trappc9 Deficiency Impairs the Plasticity of Stem Cells.

International journal of molecular sciences

Usman M,Li Y,Ke Y,Chhetri G,Islam MA,Wang Z,Li X

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunocytochemistry

Thu Apr 28 00:00:00 EDT 2022

GPR92 activation in islet macrophages controls β cell function in a diet-induced obesity model.

The Journal of clinical investigation

de Souza CO,Paschoal VA,Sun X,Vishvanath L,Zhang Q,Shao M,Onodera T,Chen S,Joffin N,Bueno LM,Gupta RK,Oh DY

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Nov 01 00:00:00 EDT 2022

Mineralocorticoid receptor antagonists and glucocorticoids differentially affect skeletal muscle inflammation and pathology in muscular dystrophy.

JCI insight

Howard ZM,Gomatam CK,Rabolli CP,Lowe J,Piepho AB,Bansal SS,Accornero F,Rafael-Fortney JA

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Oct 10 00:00:00 EDT 2022

Comparative analysis of thoracic and abdominal aortic aneurysms across the segment and species at the single-cell level.

Frontiers in pharmacology

Wu H,Xie C,Wang R,Cheng J,Xu Q,Zhao H

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Feb 02 00:00:00 EST 2023

Microglial angiotensin type 2 receptors mediate sex-specific expression of inflammatory cytokines independently of circulating estrogen.

Glia

Garrido-Gil P,Pedrosa MA,Garcia-Garrote M,Pequeño-Valtierra A,Rodríguez-Castro J,García-Souto D,Rodríguez-Pérez AI,Labandeira-Garcia JL

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Dec 01 00:00:00 EST 2022

Hematopoietic-Mesenchymal Signals Regulate the Properties of Mesenchymal Stem Cells.

International journal of molecular sciences

Kanazawa S,Okada H,Riu D,Mabuchi Y,Akazawa C,Iwata J,Hoshi K,Hikita A

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Jul 26 00:00:00 EDT 2022

Gene-selective transcription promotes the inhibition of tissue reparative macrophages by TNF.

Life science alliance

Dichtl S,Sanin DE,Koss CK,Willenborg S,Petzold A,Tanzer MC,Dahl A,Kabat AM,Lindenthal L,Zeitler L,Satzinger S,Strasser A,Mann M,Roers A,Eming SA,El Kasmi KC,Pearce EJ,Murray PJ

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Apr 01 00:00:00 EDT 2022

Intranasal delivery of a small-molecule ErbB inhibitor promotes recovery from acute and late-stage CNS inflammation.

JCI insight

Linnerbauer M,Lößlein L,Vandrey O,Tsaktanis T,Beer A,Naumann UJ,Panier F,Beyer T,Nirschl L,Kuramatsu JB,Winkler J,Quintana FJ,Rothhammer V

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Apr 08 00:00:00 EDT 2022

A Point Mutation R122C in RUNX3 Promotes the Expansion of Isthmus Stem Cells and Inhibits Their Differentiation in the Stomach.

Cellular and molecular gastroenterology and hepatology

Douchi D,Yamamura A,Matsuo J,Lee JW,Nuttonmanit N,Melissa Lim YH,Suda K,Shimura M,Chen S,Pang S,Kohu K,Kaneko M,Kiyonari H,Kaneda A,Yoshida H,Taniuchi I,Osato M,Yang H,Unno M,Bok-Yan So J,Yeoh KG,Chuang LSH,Bae SC,Ito Y

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Mon Apr 18 00:00:00 EDT 2022

Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity.

Science advances

Kumar B,Adebayo AK,Prasad M,Capitano ML,Wang R,Bhat-Nakshatri P,Anjanappa M,Simpson E,Chen D,Liu Y,Schilder JM,Colter AB,Maguire C,Temm CJ,Sandusky G,Doud EH,Wijeratne AB,Mosley AL,Broxmeyer HE,Nakshatri H

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Jan 14 00:00:00 EST 2022

The RNA-binding protein IMP2 drives a stromal-Th17 cell circuit in autoimmune neuroinflammation.

JCI insight

Bechara R,Amatya N,Majumder S,Zhou C,Li Y,Liu Q,McGeachy MJ,Gaffen SL

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Feb 08 00:00:00 EST 2022

Impact of dietary vitamin D on immunoregulation and disease pathology in lupus-prone NZB/W F1 mice.

Frontiers in immunology

Kraemer AN,Schäfer AL,Sprenger DTL,Sehnert B,Williams JP,Luo A,Riechert L,Al-Kayyal Q,Dumortier H,Fauny JD,Winter Z,Heim K,Hofmann M,Herrmann M,Heine G,Voll RE,Chevalier N

69-0451-82 was used in Flow cytometry/Cell sorting to reveal that low VD intake promotes lupus pathology, likely via the deviation of adaptive immunity, and suggests that the correction of VD deficiency might not only exert beneficial functions by preventing osteoporosis but also serve as an important module in prophylaxis and as an add-on in the treatment of lupus and possibly other immune-mediated diseases.

Fri Dec 16 00:00:00 EST 2022

Acupoint Catgut-Embedding Therapy Inhibits NF-κB/COX-2 Pathway in an Ovalbumin-Induced Mouse Model of Allergic Asthma.

BioMed research international

Teng F,Ma X,Cui J,Zhu X,Tang W,Wang W,Wuniqiemu T,Qin J,Yi L,Zong Y,Liu C,Wang S

69-0451-82 was used in Flow cytometry/Cell sorting to show that ovalbumin induction resulted in a significant increase in airway resistance , accompanied by a significant decrease in lung dynamic compliance.

Fri Apr 08 00:00:00 EDT 2022

Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19.

Cell host & microbe

Guo Q,Zhao Y,Li J,Liu J,Yang X,Guo X,Kuang M,Xia H,Zhang Z,Cao L,Luo Y,Bao L,Wang X,Wei X,Deng W,Wang N,Chen L,Chen J,Zhu H,Gao R,Qin C,Wang X,You F

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Feb 10 00:00:00 EST 2021

Stage-specific action of Runx1 and GATA3 controls silencing of PU.1 expression in mouse pro-T cells.

The Journal of experimental medicine

Hosokawa H,Koizumi M,Masuhara K,Romero-Wolf M,Tanaka T,Nakayama T,Rothenberg EV

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Aug 02 00:00:00 EDT 2021

Uptake and trafficking of different sized PLGA nanoparticles by dendritic cells in imiquimod-induced psoriasis-like mice model.

Acta pharmaceutica Sinica. B

Lin Z,Xi L,Chen S,Tao J,Wang Y,Chen X,Li P,Wang Z,Zheng Y

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Apr 01 00:00:00 EDT 2021

Mapping the origin and fate of myeloid cells in distinct compartments of the eye by single-cell profiling.

The EMBO journal

Wieghofer P,Hagemeyer N,Sankowski R,Schlecht A,Staszewski O,Amann L,Gruber M,Koch J,Hausmann A,Zhang P,Boneva S,Masuda T,Hilgendorf I,Goldmann T,Böttcher C,Priller J,Rossi FM,Lange C,Prinz M

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Mar 15 00:00:00 EDT 2021

Ablation of lysozyme M-positive cells prevents aircraft noise-induced vascular damage without improving cerebral side effects.

Basic research in cardiology

Frenis K,Helmstädter J,Ruan Y,Schramm E,Kalinovic S,Kröller-Schön S,Bayo Jimenez MT,Hahad O,Oelze M,Jiang S,Wenzel P,Sommer CJ,Frauenknecht KBM,Waisman A,Gericke A,Daiber A,Münzel T,Steven S

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Apr 30 00:00:00 EDT 2021

Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degeneration.

Cell death and differentiation

Deng CL,Hu CB,Ling ST,Zhao N,Bao LH,Zhou F,Xiong YC,Chen T,Sui BD,Yu XR,Hu CH

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Mar 01 00:00:00 EST 2021

Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin.

Cell death and differentiation

Velletri T,Huang Y,Wang Y,Li Q,Hu M,Xie N,Yang Q,Chen X,Chen Q,Shou P,Gan Y,Candi E,Annicchiarico-Petruzzelli M,Agostini M,Yang H,Melino G,Shi Y,Wang Y

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Jan 01 00:00:00 EST 2021

Decreased antiviral immune response within the central nervous system of aged mice is associated with increased lethality of West Nile virus encephalitis.

Aging cell

Funk KE,Arutyunov AD,Desai P,White JP,Soung AL,Rosen SF,Diamond MS,Klein RS

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sun Aug 01 00:00:00 EDT 2021

Deletion of mTOR in liver epithelial cells enhances hepatic metastasis of colon cancer.

The Journal of pathology

Jiao L,Eickhoff R,Egners A,Jumpertz S,Roth J,Erdem M,Kroh A,Duimel H,López-Iglesias C,Caro P,Heij LR,Schmeding M,Meierhofer D,Neumann UP,Cramer T

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Mon Nov 01 00:00:00 EDT 2021

Anti-adipogenic signals at the onset of obesity-related inflammation in white adipose tissue.

Cellular and molecular life sciences : CMLS

Caputo T,Tran VDT,Bararpour N,Winkler C,Aguileta G,Trang KB,Giordano Attianese GMP,Wilson A,Thomas A,Pagni M,Guex N,Desvergne B,Gilardi F

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Jan 01 00:00:00 EST 2021

RANKL from bone marrow adipose lineage cells promotes osteoclast formation and bone loss.

EMBO reports

Hu Y,Li X,Zhi X,Cong W,Huang B,Chen H,Wang Y,Li Y,Wang L,Fang C,Guo J,Liu Y,Cui J,Cao L,Weng W,Zhou Q,Wang S,Chen X,Su J

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Jul 05 00:00:00 EDT 2021

Macrophage polarization by MSC-derived CXCL12 determines tumor growth.

Cellular & molecular biology letters

Babazadeh S,Nassiri SM,Siavashi V,Sahlabadi M,Hajinasrollah M,Zamani-Ahmadmahmudi M

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sat Jun 26 00:00:00 EDT 2021

The effects of postmortem delay on mouse and human microglia gene expression.

Glia

Heng Y,Dubbelaar ML,Marie SKN,Boddeke EWGM,Eggen BJL

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Apr 01 00:00:00 EDT 2021

Intrinsic DNA damage repair deficiency results in progressive microglia loss and replacement.

Glia

Zhang X,Heng Y,Kooistra SM,van Weering HRJ,Brummer ML,Gerrits E,Wesseling EM,Brouwer N,Nijboer TW,Dubbelaar ML,Boddeke EWGM,Eggen BJL

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Mar 01 00:00:00 EST 2021

Intercellular Interactions of an Adipogenic CXCL12-Expressing Stromal Cell Subset in Murine Bone Marrow.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Matsushita Y,Chu AKY,Ono W,Welch JD,Ono N

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunocytochemistry

Tue Jun 01 00:00:00 EDT 2021

Intercellular Interactions of an Adipogenic CXCL12-Expressing Stromal Cell Subset in Murine Bone Marrow.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Matsushita Y,Chu AKY,Ono W,Welch JD,Ono N

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunocytochemistry

Tue Jun 01 00:00:00 EDT 2021

Macrophage LAMTOR1 Deficiency Prevents Dietary Obesity and Insulin Resistance Through Inflammation-Induced Energy Expenditure.

Frontiers in cell and developmental biology

Ying L,Zhang M,Ma X,Si Y,Li X,Su J,Yin J,Bao Y

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Jun 08 00:00:00 EDT 2021

A novel Cytochrome P450 26A1 expressing NK cell subset at the mouse maternal-foetal interface.

Journal of cellular and molecular medicine

Wei DP,Li DD,Gu AQ,Ji WH,Yang Y,Peng JP

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunocytochemistry

Mon Feb 01 00:00:00 EST 2021

Alterations of macrophage and neutrophil content in skeletal muscle of aged versus young mice.

Muscle & nerve

Kawanishi N,Machida S

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Apr 01 00:00:00 EDT 2021

Environmental allergens house dust mite-induced asthma is associated with ferroptosis in the lungs.

Experimental and therapeutic medicine

Tang W,Dong M,Teng F,Cui J,Zhu X,Wang W,Wuniqiemu T,Qin J,Yi L,Wang S,Dong J,Wei Y

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Dec 01 00:00:00 EST 2021

Environmental allergens house dust mite-induced asthma is associated with ferroptosis in the lungs.

Experimental and therapeutic medicine

Tang W,Dong M,Teng F,Cui J,Zhu X,Wang W,Wuniqiemu T,Qin J,Yi L,Wang S,Dong J,Wei Y

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Dec 01 00:00:00 EST 2021

Differential activation of Ca²⁺ influx channels modulate stem cell potency, their proliferation/viability and tissue regeneration.

NPJ Regenerative medicine

Ahamad N,Sun Y,Nascimento Da Conceicao V,Xavier Paul Ezhilan CRD,Natarajan M,Singh BB

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Wed Oct 20 00:00:00 EDT 2021

Differential activation of Ca²⁺ influx channels modulate stem cell potency, their proliferation/viability and tissue regeneration.

NPJ Regenerative medicine

Ahamad N,Sun Y,Nascimento Da Conceicao V,Xavier Paul Ezhilan CRD,Natarajan M,Singh BB

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Wed Oct 20 00:00:00 EDT 2021

Cellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue.

Nature communications

Ribas-Latre A,Santos RB,Fekry B,Tamim YM,Shivshankar S,Mohamed AMT,Baumgartner C,Kwok C,Gebhardt C,Rivera A,Gao Z,Sun K,Heiker JT,Snyder BE,Kolonin MG,Eckel-Mahan KL

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunocytochemistry

Wed Jun 09 00:00:00 EDT 2021

Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40.

Nature communications

Yang F,He Z,Duan H,Zhang D,Li J,Yang H,Dorsey JF,Zou W,Nabavizadeh SA,Bagley SJ,Abdullah K,Brem S,Zhang L,Xu X,Byrne KT,Vonderheide RH,Gong Y,Fan Y

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Jun 08 00:00:00 EDT 2021

Increased Levels of IL-16 in the Central Nervous System during Neuroinflammation Are Associated with Infiltrating Immune Cells and Resident Glial Cells.

Biology

Hridi SU,Barbour M,Wilson C,Franssen AJ,Harte T,Bushell TJ,Jiang HR

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry (Frozen)

Thu May 27 00:00:00 EDT 2021

NOX4 regulates macrophage apoptosis resistance to induce fibrotic progression.

The Journal of biological chemistry

Larson-Casey JL,Gu L,Kang J,Dhyani A,Carter AB

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Jul 01 00:00:00 EDT 2021

The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.

eLife

Roy A,Tomaz da Silva M,Bhat R,Bohnert KR,Iwawaki T,Kumar A

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Nov 23 00:00:00 EST 2021

VISTA regulates microglia homeostasis and myelin phagocytosis, and is associated with MS lesion pathology.

Acta neuropathologica communications

Borggrewe M,Kooistra SM,Wesseling EM,Gierschek FL,Brummer ML,Nowak EC,Medeiros-Furquim T,Otto TA,Lee SW,Noelle RJ,Eggen BJL,Laman JD

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Tue May 18 00:00:00 EDT 2021

The Absence of Extracellular Cold-Inducible RNA-Binding Protein (eCIRP) Promotes Pro-Angiogenic Microenvironmental Conditions and Angiogenesis in Muscle Tissue Ischemia.

International journal of molecular sciences

Kübler M,Beck S,Peffenköver LL,Götz P,Ishikawa-Ankerhold H,Preissner KT,Fischer S,Lasch M,Deindl E

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunocytochemistry

Tue Aug 31 00:00:00 EDT 2021

Apoptotic vesicles restore liver macrophage homeostasis to counteract type 2 diabetes.

Journal of extracellular vesicles

Zheng C,Sui B,Zhang X,Hu J,Chen J,Liu J,Wu D,Ye Q,Xiang L,Qiu X,Liu S,Deng Z,Zhou J,Liu S,Shi S,Jin Y

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sat May 01 00:00:00 EDT 2021

Distinct skeletal stem cell types orchestrate long bone skeletogenesis.

eLife

Ambrosi TH,Sinha R,Steininger HM,Hoover MY,Murphy MP,Koepke LS,Wang Y,Lu WJ,Morri M,Neff NF,Weissman IL,Longaker MT,Chan CK

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Jul 19 00:00:00 EDT 2021

C3 Deficiency Leads to Increased Angiogenesis and Elevated Pro-Angiogenic Leukocyte Recruitment in Ischemic Muscle Tissue.

International journal of molecular sciences

Götz P,Braumandl A,Kübler M,Kumaraswami K,Ishikawa-Ankerhold H,Lasch M,Deindl E

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Fri May 28 00:00:00 EDT 2021

Integrated OMICs unveil the bone-marrow microenvironment in human leukemia.

Cell reports

Passaro D,Garcia-Albornoz M,Diana G,Chakravarty P,Ariza-McNaughton L,Batsivari A,Borràs-Eroles C,Abarrategi A,Waclawiczek A,Ombrato L,Malanchi I,Gribben J,Bonnet D

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue May 11 00:00:00 EDT 2021

Absence of Cold-Inducible RNA-Binding Protein (CIRP) Promotes Angiogenesis and Regeneration of Ischemic Tissue by Inducing M2-Like Macrophage Polarization.

Biomedicines

Kübler M,Beck S,Fischer S,Götz P,Kumaraswami K,Ishikawa-Ankerhold H,Lasch M,Deindl E

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Wed Apr 07 00:00:00 EDT 2021

Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury.

Nature communications

Jin H,Liu K,Tang J,Huang X,Wang H,Zhang Q,Zhu H,Li Y,Pu W,Zhao H,He L,Li Y,Zhang S,Zhang Z,Zhao Y,Qin Y,Pflanz S,Kasmi KEI,Zhang W,Liu Z,Ginhoux F,Ji Y,He B,Wang L,Zhou B

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry (PFA fixed)

Mon May 17 00:00:00 EDT 2021

PTENα functions as an immune suppressor and promotes immune resistance in PTEN-mutant cancer.

Nature communications

Sun Y,Lu D,Yin Y,Song J,Liu Y,Hao W,Qi F,Zhang G,Zhang X,Liu L,Lin Z,Liang H,Zhao X,Jin Y,Yin Y

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Aug 26 00:00:00 EDT 2021

Cardiac-derived TGF-β1 confers resistance to diet-induced obesity through the regulation of adipocyte size and function.

Molecular metabolism

Longenecker JZ,Petrosino JM,Martens CR,Hinger SA,Royer CJ,Dorn LE,Branch DA,Serrano J,Stanford KI,Kyriazis GA,Baskin KK,Accornero F

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Dec 01 00:00:00 EST 2021

Determining the effect of aging, recovery time, and post-stroke memantine treatment on delayed thalamic gliosis after cortical infarct.

Scientific reports

Kim GS,Stephenson JM,Al Mamun A,Wu T,Goss MG,Min JW,Li J,Liu F,Marrelli SP

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Jun 15 00:00:00 EDT 2021

Differential neurovirulence of Usutu virus lineages in mice and neuronal cells.

Journal of neuroinflammation

Clé M,Constant O,Barthelemy J,Desmetz C,Martin MF,Lapeyre L,Cadar D,Savini G,Teodori L,Monaco F,Schmidt-Chanasit J,Saiz JC,Gonzales G,Lecollinet S,Beck C,Gosselet F,Van de Perre P,Foulongne V,Salinas S,Simonin Y

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Wed Jan 06 00:00:00 EST 2021

Transcriptional Network Analysis Reveals the Role of miR-223-5p During Diabetic Corneal Epithelial Regeneration.

Frontiers in molecular biosciences

Zhang Y,Dou S,Qi X,Zhang Z,Qiao Y,Wang Y,Xie J,Jiang H,Zhang B,Zhou Q,Wang Q,Xie L

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunocytochemistry

Thu Apr 13 00:00:00 EDT 2023

Cytochrome P450 26A1 Modulates the Polarization of Uterine Macrophages During the Peri-Implantation Period.

Frontiers in immunology

Ji WH,Li DD,Wei DP,Gu AQ,Yang Y,Peng JP

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Feb 10 00:00:00 EST 2022

A molybdenum oxide-based degradable nanosheet for combined chemo-photothermal therapy to improve tumor immunosuppression and suppress distant tumors and lung metastases.

Journal of nanobiotechnology

Qiu N,Yang X,Zhang Y,Zhang J,Ji J,Zhang Y,Kong X,Xi Y,Liu D,Ye L,Zhai G

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sun Dec 19 00:00:00 EST 2021

Visceral adipose tissue imparts peripheral macrophage influx into the hypothalamus.

Journal of neuroinflammation

Chen KE,Lainez NM,Nair MG,Coss D

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Jun 21 00:00:00 EDT 2021

Quantitative in vivo assessment of amyloid-beta phagocytic capacity in an Alzheimer's disease mouse model.

STAR protocols

Lau SF,Wu W,Seo H,Fu AKY,Ip NY

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Mar 19 00:00:00 EDT 2021

Mice with induced pulmonary morbidities display severe lung inflammation and mortality following exposure to SARS-CoV-2.

JCI insight

Falach R,Bar-On L,Lazar S,Kadar T,Mazor O,Aftalion M,Gur D,Evgy Y,Shifman O,Aminov T,Israeli O,Cohen-Gihon I,Zaide G,Gutman H,Vagima Y,Makdasi E,Stein D,Rosenfeld R,Alcalay R,Zahavy E,Levy H,Glinert I,Ben-Shmuel A,Israely T,Melamed S,Politi B,Achdout H,Yitzhaki S,Kronman C,Sabo T

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Jun 22 00:00:00 EDT 2021

Suppression of mucosal Th17 memory responses by acellular pertussis vaccines enhances nasal Bordetella pertussis carriage.

NPJ vaccines

Dubois V,Chatagnon J,Thiriard A,Bauderlique-Le Roy H,Debrie AS,Coutte L,Locht C

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Jan 08 00:00:00 EST 2021

The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia.

Journal of neuroinflammation

Malone K,Diaz Diaz AC,Shearer JA,Moore AC,Waeber C

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sat Jan 30 00:00:00 EST 2021

A decrease in NAD⁺ contributes to the loss of osteoprogenitors and bone mass with aging.

NPJ aging and mechanisms of disease

Kim HN,Ponte F,Warren A,Ring R,Iyer S,Han L,Almeida M

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Apr 01 00:00:00 EDT 2021

Therapeutic Potential of Mesenchymal Stem Cells in a Pre-Clinical Model of Diabetic Kidney Disease and Obesity.

International journal of molecular sciences

Sávio-Silva C,Soinski-Sousa PE,Simplício-Filho A,Bastos RMC,Beyerstedt S,Rangel ÉB

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Feb 04 00:00:00 EST 2021

Use of a Self-Delivering Anti-CCL3 FANA Oligonucleotide as an Innovative Approach to Target Inflammation after Spinal Cord Injury.

eNeuro

Pelisch N,Rosas Almanza J,Stehlik KE,Aperi BV,Kroner A

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Jun 18 00:00:00 EDT 2021

T cell-depleting nanoparticles ameliorate bone loss by reducing activated T cells and regulating the Treg/Th17 balance.

Bioactive materials

Yang X,Zhou F,Yuan P,Dou G,Liu X,Liu S,Wang X,Jin R,Dong Y,Zhou J,Lv Y,Deng Z,Liu S,Chen X,Han Y,Jin Y

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Oct 01 00:00:00 EDT 2021

Placenta-Expanded Stromal Cell Therapy in a Rodent Model of Simulated Weightlessness.

Cells

Rubinstein L,Paul AM,Houseman C,Abegaz M,Tabares Ruiz S,O'Neil N,Kunis G,Ofir R,Cohen J,Ronca AE,Globus RK,Tahimic CGT

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Apr 19 00:00:00 EDT 2021

Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis.

Frontiers in immunology

Yang P,Tian H,Zou YR,Chambon P,Ichinose H,Honig G,Diamond B,Kim SJ

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Jul 05 00:00:00 EDT 2021

Systemic administration of β-glucan induces immune training in microglia.

Journal of neuroinflammation

Heng Y,Zhang X,Borggrewe M,van Weering HRJ,Brummer ML,Nijboer TW,Joosten LAB,Netea MG,Boddeke EWGM,Laman JD,Eggen BJL

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Feb 22 00:00:00 EST 2021

Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation.

Nature

Jiao H,Wachsmuth L,Kumari S,Schwarzer R,Lin J,Eren RO,Fisher A,Lane R,Young GR,Kassiotis G,Kaiser WJ,Pasparakis M

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Wed Apr 01 00:00:00 EDT 2020

Macrophages Maintain Epithelium Integrity by Limiting Fungal Product Absorption.

Cell

Chikina AS,Nadalin F,Maurin M,San-Roman M,Thomas-Bonafos T,Li XV,Lameiras S,Baulande S,Henri S,Malissen B,Lacerda Mariano L,Barbazan J,Blander JM,Iliev ID,Matic Vignjevic D,Lennon-Duménil AM

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Oct 15 00:00:00 EDT 2020

The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching.

Immunity

Xu J,Zanvit P,Hu L,Tseng PY,Liu N,Wang F,Liu O,Zhang D,Jin W,Guo N,Han Y,Yin J,Cain A,Hoon MA,Wang S,Chen W

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Aug 18 00:00:00 EDT 2020

Exposure to diesel exhaust particles increases susceptibility to invasive pneumococcal disease.

The Journal of allergy and clinical immunology

Shears RK,Jacques LC,Naylor G,Miyashita L,Khandaker S,Lebre F,Lavelle EC,Grigg J,French N,Neill DR,Kadioglu A

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Apr 01 00:00:00 EDT 2020

Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.

British journal of pharmacology

De Cicco P,Ercolano G,Rubino V,Terrazzano G,Ruggiero G,Cirino G,Ianaro A

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sat Feb 01 00:00:00 EST 2020

Membrane expression of the estrogen receptor ERα is required for intercellular communications in the mammary epithelium.

Development (Cambridge, England)

Gagniac L,Rusidzé M,Boudou F,Cagnet S,Adlanmerini M,Jeannot P,Gaide N,Giton F,Besson A,Weyl A,Gourdy P,Raymond-Letron I,Arnal JF,Brisken C,Lenfant F

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Mar 11 00:00:00 EDT 2020

Dysfunction of B Cell Leading to Failure of Immunoglobulin Response Is Ameliorated by Dietary Silk Peptide in 14-Month-Old C57BL/6 Mice.

Frontiers in nutrition

Chei S,Oh HJ,Lee K,Jin H,Lee JY,Lee BY

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Dec 18 00:00:00 EST 2020

Sema3A and HIF1α co-overexpressed iPSC-MSCs/HA scaffold facilitates the repair of calvarial defect in a mouse model.

Journal of cellular physiology

Li J,Wang T,Li C,Wang Z,Wang P,Zheng L

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Oct 01 00:00:00 EDT 2020

Detection of Synaptic Proteins in Microglia by Flow Cytometry.

Frontiers in molecular neuroscience

Brioschi S,d'Errico P,Amann LS,Janova H,Wojcik SM,Meyer-Luehmann M,Rajendran L,Wieghofer P,Paolicelli RC,Biber K

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Nov 03 00:00:00 EST 2020

Quantitative single-cell interactomes in normal and virus-infected mouse lungs.

Disease models & mechanisms

Cain MP,Hernandez BJ,Chen J

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunocytochemistry

Fri Jun 26 00:00:00 EDT 2020

Extracellular HMGB-1 activates inflammatory signaling in tendon cells and tissues.

Therapeutic advances in chronic disease

Zhang C,Gu X,Zhao G,Wang W,Shao J,Zhu J,Yuan T,Sun J,Nie D,Zhou Y

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sun Apr 17 00:00:00 EDT 2022

Resveratrol rescues TNF‑α‑induced inhibition of osteogenesis in human periodontal ligament stem cells via the ERK1/2 pathway.

Molecular medicine reports

Yuan J,Wang X,Ma D,Gao H,Zheng D,Zhang J

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri May 01 00:00:00 EDT 2020

Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity.

Nature communications

von Roemeling CA,Wang Y,Qie Y,Yuan H,Zhao H,Liu X,Yang Z,Yang M,Deng W,Bruno KA,Chan CK,Lee AS,Rosenfeld SS,Yun K,Johnson AJ,Mitchell DA,Jiang W,Kim BYS

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Fri Mar 20 00:00:00 EDT 2020

Study of Usutu virus neuropathogenicity in mice and human cellular models.

PLoS neglected tropical diseases

Clé M,Barthelemy J,Desmetz C,Foulongne V,Lapeyre L,Bolloré K,Tuaillon E,Erkilic N,Kalatzis V,Lecollinet S,Beck C,Pirot N,Glasson Y,Gosselet F,Alvarez Martinez MT,Van de Perre P,Salinas S,Simonin Y

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Wed Apr 01 00:00:00 EDT 2020

Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers.

Nature communications

Okazaki K,Anzawa H,Liu Z,Ota N,Kitamura H,Onodera Y,Alam MM,Matsumaru D,Suzuki T,Katsuoka F,Tadaka S,Motoike I,Watanabe M,Hayasaka K,Sakurada A,Okada Y,Yamamoto M,Suzuki T,Kinoshita K,Sekine H,Motohashi H

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Nov 20 00:00:00 EST 2020

Eosinophils improve cardiac function after myocardial infarction.

Nature communications

Liu J,Yang C,Liu T,Deng Z,Fang W,Zhang X,Li J,Huang Q,Liu C,Wang Y,Yang D,Sukhova GK,Lindholt JS,Diederichsen A,Rasmussen LM,Li D,Newton G,Luscinskas FW,Liu L,Libby P,Wang J,Guo J,Shi GP

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Dec 16 00:00:00 EST 2020

Ly6c^Lo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation.

Scientific reports

Alkhani A,Levy CS,Tsui M,Rosenberg KA,Polovina K,Mattis AN,Mack M,Van Dyken S,Wang BM,Maher JJ,Nijagal A

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Apr 28 00:00:00 EDT 2020

Stromal CCL2 Signaling Promotes Mammary Tumor Fibrosis through Recruitment of Myeloid-Lineage Cells.

Cancers

Kuziel G,Thompson V,D'Amato JV,Arendt LM

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Jul 28 00:00:00 EDT 2020

Small GTPase RAB6 deficiency promotes alveolar progenitor cell renewal and attenuates PM2.5-induced lung injury and fibrosis.

Cell death & disease

Yang L,Liu G,Li X,Xia Z,Wang Y,Lin W,Zhang W,Zhang W,Li X

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sun Oct 04 00:00:00 EDT 2020

A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation.

Nature communications

Kim JM,Yang YS,Park KH,Ge X,Xu R,Li N,Song M,Chun H,Bok S,Charles JF,Filhol-Cochet O,Boldyreff B,Dinter T,Yu PB,Kon N,Gu W,Takarada T,Greenblatt MB,Shim JH

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri May 08 00:00:00 EDT 2020

Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement.

eLife

Kalinski AL,Yoon C,Huffman LD,Duncker PC,Kohen R,Passino R,Hafner H,Johnson C,Kawaguchi R,Carbajal KS,Jara JS,Hollis E,Geschwind DH,Segal BM,Giger RJ

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Dec 02 00:00:00 EST 2020

Resolvin D1 supports skeletal myofiber regeneration via actions on myeloid and muscle stem cells.

JCI insight

Markworth JF,Brown LA,Lim E,Floyd C,Larouche J,Castor-Macias JA,Sugg KB,Sarver DC,Macpherson PC,Davis C,Aguilar CA,Maddipati KR,Brooks SV

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Sep 17 00:00:00 EDT 2020

Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations.

Journal of neuroinflammation

Lowe PP,Morel C,Ambade A,Iracheta-Vellve A,Kwiatkowski E,Satishchandran A,Furi I,Cho Y,Gyongyosi B,Catalano D,Lefebvre E,Fischer L,Seyedkazemi S,Schafer DP,Szabo G

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Oct 09 00:00:00 EDT 2020

Delayed microglial depletion after spinal cord injury reduces chronic inflammation and neurodegeneration in the brain and improves neurological recovery in male mice.

Theranostics

Li Y,Ritzel RM,Khan N,Cao T,He J,Lei Z,Matyas JJ,Sabirzhanov B,Liu S,Li H,Stoica BA,Loane DJ,Faden AI,Wu J

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Jun 01 00:00:00 EDT 2021

Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease.

Journal of neuroinflammation

Schröder N,Schaffrath A,Welter JA,Putzka T,Griep A,Ziegler P,Brandt E,Samer S,Heneka MT,Kaddatz H,Zhan J,Kipp E,Pufe T,Tauber SC,Kipp M,Brandenburg LO

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Apr 24 00:00:00 EDT 2020

Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.

JCI insight

Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Aug 20 00:00:00 EDT 2020

Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartments.

Nature communications

Jandke A,Melandri D,Monin L,Ushakov DS,Laing AG,Vantourout P,East P,Nitta T,Narita T,Takayanagi H,Feederle R,Hayday A

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Jul 28 00:00:00 EDT 2020

Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models.

Communications biology

Waaler J,Mygland L,Tveita A,Strand MF,Solberg NT,Olsen PA,Aizenshtadt A,Fauskanger M,Lund K,Brinch SA,Lycke M,Dybing E,Nygaard V,Bøe SL,Heintz KM,Hovig E,Hammarström C,Corthay A,Krauss S

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Apr 24 00:00:00 EDT 2020

Zika Virus Infection Promotes Local Inflammation, Cell Adhesion Molecule Upregulation, and Leukocyte Recruitment at the Blood-Brain Barrier.

mBio

Clé M,Desmetz C,Barthelemy J,Martin MF,Constant O,Maarifi G,Foulongne V,Bolloré K,Glasson Y,De Bock F,Blaquiere M,Dehouck L,Pirot N,Tuaillon E,Nisole S,Najioullah F,Van de Perre P,Cabié A,Marchi N,Gosselet F,Simonin Y,Salinas S

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Tue Aug 04 00:00:00 EDT 2020

PPARγ inhibition boosts efficacy of PD-L1 Checkpoint Blockade Immunotherapy against Murine Melanoma in a sexually dimorphic manner.

International journal of biological sciences

Wu B,Sun X,Yuan B,Ge F,Gupta HB,Chiang HC,Li J,Hu Y,Curiel TJ,Li R

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Aug 23 00:00:00 EDT 2021

A Synthetic Small Molecule F240B Decreases NLRP3 Inflammasome Activation by Autophagy Induction.

Frontiers in immunology

Wu CH,Gan CH,Li LH,Chang JC,Chen ST,Menon MP,Cheng SM,Yang SP,Ho CL,Chernikov OV,Lin CH,Lam Y,Hua KF

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Jun 23 00:00:00 EDT 2021

CNS Immune Profiling in a Dengue Virus-Infected Immunocompetent Outbred ICR Mice Strain.

Frontiers in cellular and infection microbiology

Shen TJ,Chen CL,Jhan MK,Tseng PC,Lin CF

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Jun 17 00:00:00 EDT 2021

Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages.

Stem cell research & therapy

Liu J,Qiu X,Lv Y,Zheng C,Dong Y,Dou G,Zhu B,Liu A,Wang W,Zhou J,Liu S,Liu S,Gao B,Jin Y

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Nov 27 00:00:00 EST 2020

Prodrug-Loaded Zirconium Carbide Nanosheets as a Novel Biophotonic Nanoplatform for Effective Treatment of Cancer.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Liu Q,Xie Z,Qiu M,Shim I,Yang Y,Xie S,Yang Q,Wang D,Chen S,Fan T,Ding B,Guo Z,Adah D,Yao X,Zhang Y,Wu H,Wu Z,Wei C,Wang H,Kim HS,Zou Q,Yan Q,Cai Z,Kim JS,Liu LP,Zhang H,Cao Y

69-0451-82 was used in Flow Cytometry to unravel a promising biphotonic strategy for precision treatment of cancer.

Tue Dec 01 00:00:00 EST 2020

Phosphatase SHP1 impedes mesenchymal stromal cell immunosuppressive capacity modulated by JAK1/STAT3 and P38 signals.

Cell & bioscience

Jiang M,Ye J,Wang X,Li N,Wang Y,Shi Y

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Apr 14 00:00:00 EDT 2022

Mesenchymal Stromal Cell-Derived Exosomes Contribute to Epithelial Regeneration in Experimental Inflammatory Bowel Disease.

Cellular and molecular gastroenterology and hepatology

Barnhoorn MC,Plug L,Jonge ESMM,Molenkamp D,Bos E,Schoonderwoerd MJA,Corver WE,van der Meulen-de Jong AE,Verspaget HW,Hawinkels LJAC

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon May 10 00:00:00 EDT 2021

The ROP16III-dependent early immune response determines the subacute CNS immune response and type III Toxoplasma gondii survival.

PLoS pathogens

Tuladhar S,Kochanowsky JA,Bhaskara A,Ghotmi Y,Chandrasekaran S,Koshy AA

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Oct 01 00:00:00 EDT 2019

Distinct Tie2 tyrosine phosphorylation sites dictate phenotypic switching in endothelial progenitor cells.

Journal of cellular physiology

Siavashi V,Nassiri SM,Rahbarghazi R,Mohseni Z,Sharifi AM

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed May 01 00:00:00 EDT 2019

Protumoral bone marrow-derived cells migrate via Gβγ-dependent signaling pathways and exhibit a complex repertoire of RhoGEFs.

Journal of cell communication and signaling

Cervantes-Villagrana RD,Color-Aparicio VM,Reyes-Cruz G,Vázquez-Prado J

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sat Jun 01 00:00:00 EDT 2019

Antiallodynic Effects of Cannabinoid Receptor 2 (CB₂R) Agonists on Retrovirus Infection-Induced Neuropathic Pain.

Pain research & management

Sheng WS,Chauhan P,Hu S,Prasad S,Lokensgard JR

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Dec 16 00:00:00 EST 2019

Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.

Anti-cancer drugs

Zhou Y,Fu C,Kong Y,Pan D,Wang Y,Huang S,Li Z,Ning Z,Lu X,Shan S,Xin L

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Oct 01 00:00:00 EDT 2019

Atherogenesis in the Carotid Artery with and without Interrupted Blood Flow of Two Hyperlipidemic Mouse Strains.

Journal of vascular research

Zhao J,Huangfu C,Chang Z,Grainger AT,Liu Z,Shi W

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Jan 27 00:00:00 EST 2020

Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis.

eLife

Walsh CM,Hill RZ,Schwendinger-Schreck J,Deguine J,Brock EC,Kucirek N,Rifi Z,Wei J,Gronert K,Brem RB,Barton GM,Bautista DM

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Oct 21 00:00:00 EDT 2019

Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis.

eLife

Walsh CM,Hill RZ,Schwendinger-Schreck J,Deguine J,Brock EC,Kucirek N,Rifi Z,Wei J,Gronert K,Brem RB,Barton GM,Bautista DM

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Oct 21 00:00:00 EDT 2019

CSF1R antagonism limits local restimulation of antiviral CD8⁺ T cells during viral encephalitis.

Journal of neuroinflammation

Funk KE,Klein RS

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Jan 31 00:00:00 EST 2019

Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins.

eLife

Lim J,Park H,Heisler J,Maculins T,Roose-Girma M,Xu M,Mckenzie B,van Lookeren Campagne M,Newton K,Murthy A

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Jul 09 00:00:00 EDT 2019

The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression.

Nature communications

Huang J,Zhao L,Fan Y,Liao L,Ma PX,Xiao G,Chen D

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Jun 28 00:00:00 EDT 2019

MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.

Journal for immunotherapy of cancer

Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Nov 28 00:00:00 EST 2019

Muscularis Propria Macrophages Alter the Proportion of Nitrergic but Not Cholinergic Gastric Myenteric Neurons.

Cellular and molecular gastroenterology and hepatology

Cipriani G,Terhaar ML,Eisenman ST,Ji S,Linden DR,Wright AM,Sha L,Ordog T,Szurszewski JH,Gibbons SJ,Farrugia G

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Jun 04 00:00:00 EDT 2019

Exposure to Cigarette Smoke Augments Post-ischemic Brain Injury and Inflammation via Mobilization of Neutrophils and Monocytes.

Frontiers in immunology

Li H,Li X,Gao S,Wang D,Gao X,Li Y,Wang X,Cui Z,Ma H,Liu Q,Li M

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Sep 28 00:00:00 EDT 2020

NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis.

Nature communications

Ershaid N,Sharon Y,Doron H,Raz Y,Shani O,Cohen N,Monteran L,Leider-Trejo L,Ben-Shmuel A,Yassin M,Gerlic M,Ben-Baruch A,Pasmanik-Chor M,Apte R,Erez N

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Sep 26 00:00:00 EDT 2019

Dietary calories and lipids synergistically shape adipose tissue cellularity during postnatal growth.

Molecular metabolism

Meln I,Wolff G,Gajek T,Koddebusch J,Lerch S,Harbrecht L,Hong W,Bayindir-Buchhalter I,Krunic D,Augustin HG,Vegiopoulos A

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sat Jun 01 00:00:00 EDT 2019

FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy.

eLife

Diaz Osterman CJ,Ozmadenci D,Kleinschmidt EG,Taylor KN,Barrie AM,Jiang S,Bean LM,Sulzmaier FJ,Jean C,Tancioni I,Anderson K,Uryu S,Cordasco EA,Li J,Chen XL,Fu G,Ojalill M,Rappu P,Heino J,Mark AM,Xu G,Fisch KM,Kolev VN,Weaver DT,Pachter JA,Győrffy B,McHale MT,Connolly DC,Molinolo A,Stupack DG,Schlaepfer DD

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Sep 03 00:00:00 EDT 2019

PDGFRα⁺ stromal adipocyte progenitors transition into epithelial cells during lobulo-alveologenesis in the murine mammary gland.

Nature communications

Joshi PA,Waterhouse PD,Kasaian K,Fang H,Gulyaeva O,Sul HS,Boutros PC,Khokha R

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Apr 15 00:00:00 EDT 2019

Growth Factor Screening in Dystrophic Muscles Reveals PDGFB/PDGFRB-Mediated Migration of Interstitial Stem Cells.

International journal of molecular sciences

Camps J,Grosemans H,Gijsbers R,Maes C,Sampaolesi M

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Mar 05 00:00:00 EST 2019

Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.

Cell

Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Jun 28 00:00:00 EDT 2018

Chanzyme TRPM7 Mediates the Ca²⁺ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation.

Immunity

Schappe MS,Szteyn K,Stremska ME,Mendu SK,Downs TK,Seegren PV,Mahoney MA,Dixit S,Krupa JK,Stipes EJ,Rogers JS,Adamson SE,Leitinger N,Desai BN

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Jan 16 00:00:00 EST 2018

E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.

Immunity

Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Feb 20 00:00:00 EST 2018

Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling.

Cell stem cell

Verma M,Asakura Y,Murakonda BSR,Pengo T,Latroche C,Chazaud B,McLoon LK,Asakura A

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Oct 04 00:00:00 EDT 2018

Endothelial cells in the innate response to allergens and initiation of atopic asthma.

The Journal of clinical investigation

Asosingh K,Weiss K,Queisser K,Wanner N,Yin M,Aronica M,Erzurum S

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Jul 02 00:00:00 EDT 2018

Endothelial cells in the innate response to allergens and initiation of atopic asthma.

The Journal of clinical investigation

Asosingh K,Weiss K,Queisser K,Wanner N,Yin M,Aronica M,Erzurum S

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Jul 02 00:00:00 EDT 2018

Defective germline reprogramming rewires the spermatogonial transcriptome.

Nature structural & molecular biology

Vasiliauskaitė L,Berrens RV,Ivanova I,Carrieri C,Reik W,Enright AJ,O'Carroll D

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue May 01 00:00:00 EDT 2018

11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis.

Journal of autoimmunity

Hardy RS,Fenton C,Croft AP,Naylor AJ,Begum R,Desanti G,Buckley CD,Lavery G,Cooper MS,Raza K

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Aug 01 00:00:00 EDT 2018

Inhibition of the JNK/MAPK signaling pathway by myogenesis-associated miRNAs is required for skeletal muscle development.

Cell death and differentiation

Xie SJ,Li JH,Chen HF,Tan YY,Liu SR,Zhang Y,Xu H,Yang JH,Liu S,Zheng LL,Huang MB,Guo YH,Zhang Q,Zhou H,Qu LH

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sat Sep 01 00:00:00 EDT 2018

Shared and independent functions of aPKCλ and Par3 in skin tumorigenesis.

Oncogene

Vorhagen S,Kleefisch D,Persa OD,Graband A,Schwickert A,Saynisch M,Leitges M,Niessen CM,Iden S

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunofluorescence

Sat Sep 01 00:00:00 EDT 2018

VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases.

Glia

Borggrewe M,Grit C,Den Dunnen WFA,Burm SM,Bajramovic JJ,Noelle RJ,Eggen BJL,Laman JD

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sat Dec 01 00:00:00 EST 2018

Protease-activated receptor-2 signaling through β-arrestin-2 mediates Alternaria alkaline serine protease-induced airway inflammation.

American journal of physiology. Lung cellular and molecular physiology

Yee MC,Nichols HL,Polley D,Saifeddine M,Pal K,Lee K,Wilson EH,Daines MO,Hollenberg MD,Boitano S,DeFea KA

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sat Dec 01 00:00:00 EST 2018

MyD88 is required for satellite cell-mediated myofiber regeneration in dystrophin-deficient mdx mice.

Human molecular genetics

Gallot YS,Straughn AR,Bohnert KR,Xiong G,Hindi SM,Kumar A

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Oct 01 00:00:00 EDT 2018

Isolation of a unique hepatic stellate cell population expressing integrin α8 from embryonic mouse livers.

Developmental dynamics : an official publication of the American Association of Anatomists

Ogawa T,Li Y,Lua I,Hartner A,Asahina K

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunofluorescence

Fri Jun 01 00:00:00 EDT 2018

Simultaneous Inhibition of MEK and Hh Signaling Reduces Pancreatic Cancer Metastasis.

Cancers

Gu D,Lin H,Zhang X,Fan Q,Chen S,Shahda S,Liu Y,Sun J,Xie J

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Fri Oct 26 00:00:00 EDT 2018

Nur77 variants solely comprising the amino-terminal domain activate hypoxia-inducible factor-1α and affect bone marrow homeostasis in mice and humans.

The Journal of biological chemistry

Koenis DS,Medzikovic L,Vos M,Beldman TJ,van Loenen PB,van Tiel CM,Hamers AAJ,Otermin Rubio I,de Waard V,de Vries CJM

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Fri Sep 28 00:00:00 EDT 2018

A patient derived xenograft model of cervical cancer and cervical dysplasia.

PloS one

Larmour LI,Cousins FL,Teague JA,Deane JA,Jobling TW,Gargett CE

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunofluorescence

Fri Mar 29 00:00:00 EDT 2019

A patient derived xenograft model of cervical cancer and cervical dysplasia.

PloS one

Larmour LI,Cousins FL,Teague JA,Deane JA,Jobling TW,Gargett CE

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunofluorescence

Fri Mar 29 00:00:00 EDT 2019

MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis.

Nature communications

Clemente C,Rius C,Alonso-Herranz L,Martín-Alonso M,Pollán Á,Camafeita E,Martínez F,Mota RA,Núñez V,Rodríguez C,Seiki M,Martínez-González J,Andrés V,Ricote M,Arroyo AG

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Mar 02 00:00:00 EST 2018

mTOR Modulates CD8+ T Cell Differentiation in Mice with Invasive Pulmonary Aspergillosis.

Open life sciences

Wang H,Xiao Y,Su L,Cui N,Liu D

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Jan 01 00:00:00 EST 2018

Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells.

Nature communications

Tosic M,Allen A,Willmann D,Lepper C,Kim J,Duteil D,Schüle R

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Jan 25 00:00:00 EST 2018

Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice.

Frontiers in immunology

Lainez NM,Jonak CR,Nair MG,Ethell IM,Wilson EH,Carson MJ,Coss D

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Sep 25 00:00:00 EDT 2019

Adipocyte hypertrophy and lipid dynamics underlie mammary gland remodeling after lactation.

Nature communications

Zwick RK,Rudolph MC,Shook BA,Holtrup B,Roth E,Lei V,Van Keymeulen A,Seewaldt V,Kwei S,Wysolmerski J,Rodeheffer MS,Horsley V

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Sep 04 00:00:00 EDT 2018

ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases.

Frontiers in immunology

Glal D,Sudhakar JN,Lu HH,Liu MC,Chiang HY,Liu YC,Cheng CF,Shui JW

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Sep 26 00:00:00 EDT 2019

Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.

Nature communications

Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Jun 22 00:00:00 EDT 2018

Rap1 deficiency-provoked paracrine dysfunction impairs immunosuppressive potency of mesenchymal stem cells in allograft rejection of heart transplantation.

Cell death & disease

Ding Y,Liang X,Zhang Y,Yi L,Shum HC,Chen Q,Chan BP,Fan H,Liu Z,Tergaonkar V,Qi Z,Tse HF,Lian Q

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Mar 07 00:00:00 EST 2018

Partial depletion of CD206-positive M2-like macrophages induces proliferation of beige progenitors and enhances browning after cold stimulation.

Scientific reports

Igarashi Y,Nawaz A,Kado T,Bilal M,Kuwano T,Yamamoto S,Sasahara M,Jiuxiang X,Inujima A,Koizumi K,Imura J,Shibahara N,Usui I,Fujisaka S,Tobe K

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Oct 01 00:00:00 EDT 2018

Differential cytokine contributions of perivascular haematopoietic stem cell niches.

Nature cell biology

Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2017

A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.

The Journal of clinical investigation

Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2017

Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination.

Cancer research

Jiang H,Rivera-Molina Y,Gomez-Manzano C,Clise-Dwyer K,Bover L,Vence LM,Yuan Y,Lang FF,Toniatti C,Hossain MB,Fueyo J

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sat Jul 15 00:00:00 EDT 2017

Sigma-1 receptors control immune-driven peripheral opioid analgesia during inflammation in mice.

Proceedings of the National Academy of Sciences of the United States of America

Tejada MA,Montilla-García A,Cronin SJ,Cikes D,Sánchez-Fernández C,González-Cano R,Ruiz-Cantero MC,Penninger JM,Vela JM,Baeyens JM,Cobos EJ

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Aug 01 00:00:00 EDT 2017

Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity.

Breast cancer research : BCR

Chamberlin T,D'Amato JV,Arendt LM

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Nov 29 00:00:00 EST 2017

Depletion of microglia exacerbates postischemic inflammation and brain injury.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Jin WN,Shi SX,Li Z,Li M,Wood K,Gonzales RJ,Liu Q

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Jun 01 00:00:00 EDT 2017

An atypical role for the myeloid receptor Mincle in central nervous system injury.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Arumugam TV,Manzanero S,Furtado M,Biggins PJ,Hsieh YH,Gelderblom M,MacDonald KP,Salimova E,Li YI,Korn O,Dewar D,Macrae IM,Ashman RB,Tang SC,Rosenthal NA,Ruitenberg MJ,Magnus T,Wells CA

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Jun 01 00:00:00 EDT 2017

Role of Triggering Receptor Expressed on Myeloid Cell-1 Expression in Mammalian Target of Rapamycin Modulation of CD8⁺ T-cell Differentiation during the Immune Response to Invasive Pulmonary Aspergillosis.

Chinese medical journal

Cui N,Wang H,Su LX,Zhang JH,Long Y,Liu DW

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sat May 20 00:00:00 EDT 2017

Cornea lymphatics drive the CD8⁺ T-cell response to herpes simplex virus-1.

Immunology and cell biology

Gurung HR,Carr MM,Carr DJ

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sun Jan 01 00:00:00 EST 2017

Dimethyl fumarate treatment after traumatic brain injury prevents depletion of antioxidative brain glutathione and confers neuroprotection.

Journal of neurochemistry

Krämer T,Grob T,Menzel L,Hirnet T,Griemert E,Radyushkin K,Thal SC,Methner A,Schaefer MKE

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Fri Dec 01 00:00:00 EST 2017

Cytochrome P450 26A1 modulates natural killer cells in mouse early pregnancy.

Journal of cellular and molecular medicine

Meng CY,Li ZY,Fang WN,Song ZH,Yang DD,Li DD,Yang Y,Peng JP

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sat Apr 01 00:00:00 EDT 2017

β3-Adrenergic Regulation of EPC Features Through Manipulation of the Bone Marrow MSC Niche.

Journal of cellular biochemistry

Vafaei R,Nassiri SM,Siavashi V

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Dec 01 00:00:00 EST 2017

The common parasite Toxoplasma gondii induces prostatic inflammation and microglandular hyperplasia in a mouse model.

The Prostate

Colinot DL,Garbuz T,Bosland MC,Wang L,Rice SE,Sullivan WJ,Arrizabalaga G,Jerde TJ

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sat Jul 01 00:00:00 EDT 2017

Reduced Expression of VAMP8 in Lacrimal Gland Affected by Chronic Graft-versus-Host Disease.

Journal of ophthalmology

Fukui M,Ogawa Y,Mukai S,Kamoi M,Asato T,Kawakami Y,Tsubota K

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunofluorescence

Thu Mar 10 00:00:00 EST 2022

Heavy Chain-Hyaluronan/Pentraxin 3 from Amniotic Membrane Suppresses Inflammation and Scarring in Murine Lacrimal Gland and Conjunctiva of Chronic Graft-versus-Host Disease.

Scientific reports

Ogawa Y,He H,Mukai S,Imada T,Nakamura S,Su CW,Mahabole M,Tseng SC,Tsubota K

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunofluorescence

Mon Feb 06 00:00:00 EST 2017

The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration.

eLife

Xiong G,Hindi SM,Mann AK,Gallot YS,Bohnert KR,Cavener DR,Whittemore SR,Kumar A

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Mar 23 00:00:00 EDT 2017

microRNA-449a modulates medullary thymic epithelial cell differentiation.

Scientific reports

Chen P,Zhang H,Sun X,Hu Y,Jiang W,Liu Z,Liu S,Zhang X

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Nov 21 00:00:00 EST 2017

Tristetraprolin expression by keratinocytes controls local and systemic inflammation.

JCI insight

Andrianne M,Assabban A,La C,Mogilenko D,Salle DS,Fleury S,Doumont G,Van Simaeys G,Nedospasov SA,Blackshear PJ,Dombrowicz D,Goriely S,Van Maele L

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Jun 02 00:00:00 EDT 2017

The Interleukin (IL)-1R1 pathway is a critical negative regulator of PyMT-mediated mammary tumorigenesis and pulmonary metastasis.

Oncoimmunology

Dagenais M,Dupaul-Chicoine J,Douglas T,Champagne C,Morizot A,Saleh M

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Jan 12 00:00:00 EST 2021

Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB.

PloS one

Gao SY,Zheng GS,Wang L,Liang YJ,Zhang SE,Lao XM,Li K,Liao GQ

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Sep 18 00:00:00 EDT 2017

Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces.

JCI insight

Azzam KM,Madenspacher JH,Cain DW,Lai L,Gowdy KM,Rai P,Janardhan K,Clayton N,Cunningham W,Jensen H,Patel PS,Kearney JF,Taylor GA,Fessler MB

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Aug 17 00:00:00 EDT 2017

Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis.

Stem cell reports

Redgrave RE,Tual-Chalot S,Davison BJ,Singh E,Hall D,Amirrasouli MM,Gilchrist D,Medvinsky A,Arthur HM

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue May 09 00:00:00 EDT 2017

The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity.

Cell

Moroishi T,Hayashi T,Pan WW,Fujita Y,Holt MV,Qin J,Carson DA,Guan KL

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunofluorescence

Thu Dec 01 00:00:00 EST 2016

Classical dendritic cells are required for dietary antigen-mediated induction of peripheral T(reg) cells and tolerance.

Nature immunology

Esterházy D,Loschko J,London M,Jove V,Oliveira TY,Mucida D

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sun May 01 00:00:00 EDT 2016

Oligodendrocyte death results in immune-mediated CNS demyelination.

Nature neuroscience

Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Jan 01 00:00:00 EST 2016

The breast tumor microenvironment alters the phenotype and function of natural killer cells.

Cellular & molecular immunology

Krneta T,Gillgrass A,Chew M,Ashkar AA

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Sep 01 00:00:00 EDT 2016

Non-Cell-Autonomous Regulation of Prostate Epithelial Homeostasis by Androgen Receptor.

Molecular cell

Zhang B,Kwon OJ,Henry G,Malewska A,Wei X,Zhang L,Brinkley W,Zhang Y,Castro PD,Titus M,Chen R,Sayeeduddin M,Raj GV,Mauck R,Roehrborn C,Creighton CJ,Strand DW,Ittmann MM,Xin L

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Sep 15 00:00:00 EDT 2016

Endothelin A receptor activation on mesangial cells initiates Alport glomerular disease.

Kidney international

Dufek B,Meehan DT,Delimont D,Cheung L,Gratton MA,Phillips G,Song W,Liu S,Cosgrove D

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunofluorescence

Mon Aug 01 00:00:00 EDT 2016

Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification.

Annals of surgery

Loder S,Agarwal S,Sorkin M,Breuler C,Li J,Peterson J,Gardenier J,Hsieh HH,Wang SC,Mehrara BJ,Levi B

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Dec 01 00:00:00 EST 2016

Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice.

Proceedings of the National Academy of Sciences of the United States of America

Nishio M,Sugimachi K,Goto H,Wang J,Morikawa T,Miyachi Y,Takano Y,Hikasa H,Itoh T,Suzuki SO,Kurihara H,Aishima S,Leask A,Sasaki T,Nakano T,Nishina H,Nishikawa Y,Sekido Y,Nakao K,Shin-Ya K,Mimori K,Suzuki A

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunofluorescence

Tue Jan 05 00:00:00 EST 2016

Overexpression of PIK3CA in murine head and neck epithelium drives tumor invasion and metastasis through PDK1 and enhanced TGFβ signaling.

Oncogene

Du L,Chen X,Cao Y,Lu L,Zhang F,Bornstein S,Li Y,Owens P,Malkoski S,Said S,Jin F,Kulesz-Martin M,Gross N,Wang XJ,Lu SL

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Thu Sep 01 00:00:00 EDT 2016

Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification.

Stem cells (Dayton, Ohio)

Agarwal S,Loder SJ,Sorkin M,Li S,Shrestha S,Zhao B,Mishina Y,James AW,Levi B

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunofluorescence

Wed Jun 01 00:00:00 EDT 2016

Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification.

Stem cells (Dayton, Ohio)

Agarwal S,Loder SJ,Sorkin M,Li S,Shrestha S,Zhao B,Mishina Y,James AW,Levi B

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunofluorescence

Wed Jun 01 00:00:00 EDT 2016

Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.

Journal of immunology (Baltimore, Md. : 1950)

Menendez CM,Jinkins JK,Carr DJ

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Aug 15 00:00:00 EDT 2016

ECM-Dependence of Endothelial Progenitor Cell Features.

Journal of cellular biochemistry

Siavashi V,Nassiri SM,Rahbarghazi R,Vafaei R,Sariri R

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Aug 01 00:00:00 EDT 2016

Effects of nerve growth factor and basic fibroblast growth factor dual gene modification on rat bone marrow mesenchymal stem cell differentiation into neuron-like cells in vitro.

Molecular medicine reports

Hu Y,Zhang Y,Tian K,Xun C,Wang S,Lv D

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Jan 01 00:00:00 EST 2016

A flow cytometric approach to analyzing mature and progenitor endothelial cells following traumatic brain injury.

Journal of neuroscience methods

Assis-Nascimento P,Umland O,Cepero ML,Liebl DJ

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Apr 01 00:00:00 EDT 2016

Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney.

JCI insight

Sato Y,Mii A,Hamazaki Y,Fujita H,Nakata H,Masuda K,Nishiyama S,Shibuya S,Haga H,Ogawa O,Shimizu A,Narumiya S,Kaisho T,Arita M,Yanagisawa M,Miyasaka M,Sharma K,Minato N,Kawamoto H,Yanagita M

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Thu Jul 21 00:00:00 EDT 2016

A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.

Nature communications

Jeric I,Maurer G,Cavallo AL,Raguz J,Desideri E,Tarkowski B,Parrini M,Fischer I,Zatloukal K,Baccarini M

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Dec 21 00:00:00 EST 2016

Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.

Nature communications

Ruhland MK,Loza AJ,Capietto AH,Luo X,Knolhoff BL,Flanagan KC,Belt BA,Alspach E,Leahy K,Luo J,Schaffer A,Edwards JR,Longmore G,Faccio R,DeNardo DG,Stewart SA

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Jun 08 00:00:00 EDT 2016

Targeting VEGF-A in myeloid cells enhances natural killer cell responses to chemotherapy and ameliorates cachexia.

Nature communications

Klose R,Krzywinska E,Castells M,Gotthardt D,Putz EM,Kantari-Mimoun C,Chikdene N,Meinecke AK,Schrödter K,Helfrich I,Fandrey J,Sexl V,Stockmann C

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Aug 19 00:00:00 EDT 2016

Protein Kinase D2 Protects against Acute Colitis Induced by Dextran Sulfate Sodium in Mice.

Scientific reports

Xiong J,Zhou MF,Wang YD,Chen LP,Xu WF,Wang YD,Deng F,Liu SD

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Sep 23 00:00:00 EDT 2016

Preparation of Single Cell Suspensions from Mouse Aorta.

Bio-protocol

Hu D,Yin C,Mohanta SK,Weber C,Habenicht AJ

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sun Jun 05 00:00:00 EDT 2016

Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma.

Oncoimmunology

Vandenberk L,Garg AD,Verschuere T,Koks C,Belmans J,Beullens M,Agostinis P,De Vleeschouwer S,Van Gool SW

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Feb 01 00:00:00 EST 2016

Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.

Scientific reports

Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Jun 15 00:00:00 EDT 2016

LTβR controls thymic portal endothelial cells for haematopoietic progenitor cell homing and T-cell regeneration.

Nature communications

Shi Y,Wu W,Chai Q,Li Q,Hou Y,Xia H,Ren B,Xu H,Guo X,Jin C,Lv M,Wang Z,Fu YX,Zhu M

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Aug 05 00:00:00 EDT 2016

Parent stem cells can serve as niches for their daughter cells.

Nature

Pardo-Saganta A,Tata PR,Law BM,Saez B,Chow RD,Prabhu M,Gridley T,Rajagopal J

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunofluorescence

Thu Jul 30 00:00:00 EDT 2015

Host microbiota constantly control maturation and function of microglia in the CNS.

Nature neuroscience

Erny D,Hrabě de Angelis AL,Jaitin D,Wieghofer P,Staszewski O,David E,Keren-Shaul H,Mahlakoiv T,Jakobshagen K,Buch T,Schwierzeck V,Utermöhlen O,Chun E,Garrett WS,McCoy KD,Diefenbach A,Staeheli P,Stecher B,Amit I,Prinz M

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Jul 01 00:00:00 EDT 2015

Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells.

The Journal of clinical investigation

Gori JL,Butler JM,Chan YY,Chandrasekaran D,Poulos MG,Ginsberg M,Nolan DJ,Elemento O,Wood BL,Adair JE,Rafii S,Kiem HP

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Mar 02 00:00:00 EST 2015

Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus.

EMBO molecular medicine

Herbst S,Shah A,Mazon Moya M,Marzola V,Jensen B,Reed A,Birrell MA,Saijo S,Mostowy S,Shaunak S,Armstrong-James D

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sun Mar 01 00:00:00 EST 2015

Tracking and Functional Characterization of Epithelial-Mesenchymal Transition and Mesenchymal Tumor Cells during Prostate Cancer Metastasis.

Cancer research

Ruscetti M,Quach B,Dadashian EL,Mulholland DJ,Wu H

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Jul 01 00:00:00 EDT 2015

Atypical chemokine receptor 1 deficiency reduces atherogenesis in ApoE-knockout mice.

Cardiovascular research

Wan W,Liu Q,Lionakis MS,Marino AP,Anderson SA,Swamydas M,Murphy PM

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Jun 01 00:00:00 EDT 2015

Brahma is required for cell cycle arrest and late muscle gene expression during skeletal myogenesis.

EMBO reports

Albini S,Coutinho Toto P,Dall'Agnese A,Malecova B,Cenciarelli C,Felsani A,Caruso M,Bultman SJ,Puri PL

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunofluorescence

Sat Aug 01 00:00:00 EDT 2015

The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma.

eLife

Krah NM,De La O JP,Swift GH,Hoang CQ,Willet SG,Chen Pan F,Cash GM,Bronner MP,Wright CV,MacDonald RJ,Murtaugh LC

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunofluorescence

Tue Jul 07 00:00:00 EDT 2015

Conditional immortalization of primary adipocyte precursor cells.

Adipocyte

Church C,Brown M,Rodeheffer MS

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Aug 10 00:00:00 EDT 2015

Nonadherent culture method downregulates stem cell antigen-1 expression in mouse bone marrow mesenchymal stem cells.

Experimental and therapeutic medicine

Deng B,Deng W,Xiao P,Zeng K,Zhang S,Zhang H,Deng DY,Yang Y

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Jul 01 00:00:00 EDT 2015

Endothelial Gata5 transcription factor regulates blood pressure.

Nature communications

Messaoudi S,He Y,Gutsol A,Wight A,Hébert RL,Vilmundarson RO,Makrigiannis AP,Chalmers J,Hamet P,Tremblay J,McPherson R,Stewart AFR,Touyz RM,Nemer M

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Nov 30 00:00:00 EST 2015

Endothelial Gata5 transcription factor regulates blood pressure.

Nature communications

Messaoudi S,He Y,Gutsol A,Wight A,Hébert RL,Vilmundarson RO,Makrigiannis AP,Chalmers J,Hamet P,Tremblay J,McPherson R,Stewart AFR,Touyz RM,Nemer M

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Nov 30 00:00:00 EST 2015

Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.

PloS one

Tähtinen S,Kaikkonen S,Merisalo-Soikkeli M,Grönberg-Vähä-Koskela S,Kanerva A,Parviainen S,Vähä-Koskela M,Hemminki A

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Apr 28 00:00:00 EDT 2016

Distinct in vitro properties of embryonic and extraembryonic fibroblast-like cells are reflected in their in vivo behavior following grafting in the adult mouse brain.

Cell transplantation

Costa R,Bergwerf I,Santermans E,De Vocht N,Praet J,Daans J,Le Blon D,Hoornaert C,Reekmans K,Hens N,Goossens H,Berneman Z,Parolini O,Alviano F,Ponsaerts P

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Nov 16 00:00:00 EST 2015

The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance.

Cell reports

Hermann-Kleiter N,Klepsch V,Wallner S,Siegmund K,Klepsch S,Tuzlak S,Villunger A,Kaminski S,Pfeifhofer-Obermair C,Gruber T,Wolf D,Baier G

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Sep 29 00:00:00 EDT 2015

Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.

PloS one

Szulzewsky F,Pelz A,Feng X,Synowitz M,Markovic D,Langmann T,Holtman IR,Wang X,Eggen BJ,Boddeke HW,Hambardzumyan D,Wolf SA,Kettenmann H

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Jan 12 00:00:00 EST 2016

Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts.

Stem cell reports

Neri T,Muggeo S,Paulis M,Caldana ME,Crisafulli L,Strina D,Focarelli ML,Faggioli F,Recordati C,Scaramuzza S,Scanziani E,Mantero S,Buracchi C,Sobacchi C,Lombardo A,Naldini L,Vezzoni P,Villa A,Ficara F

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Oct 13 00:00:00 EDT 2015

Cardiac telocytes and fibroblasts in primary culture: different morphologies and immunophenotypes.

PloS one

Bei Y,Zhou Q,Fu S,Lv D,Chen P,Chen Y,Wang F,Xiao J

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Nov 11 00:00:00 EST 2015

Galectin-3 deficiency exacerbates hyperglycemia and the endothelial response to diabetes.

Cardiovascular diabetology

Darrow AL,Shohet RV

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Sat Jun 06 00:00:00 EDT 2015

Reprogramming human endothelial cells to haematopoietic cells requires vascular induction.

Nature

Sandler VM,Lis R,Liu Y,Kedem A,James D,Elemento O,Butler JM,Scandura JM,Rafii S

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Jul 17 00:00:00 EDT 2014

Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells.

Journal of biomedical science

Cheng CC,Lee YH,Lin SP,Huangfu WC,Liu IH

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Mar 13 00:00:00 EDT 2014

Astrocytic transforming growth factor-beta signaling reduces subacute neuroinflammation after stroke in mice.

Glia

Cekanaviciute E,Fathali N,Doyle KP,Williams AM,Han J,Buckwalter MS

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Aug 01 00:00:00 EDT 2014

Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.

Stem cells (Dayton, Ohio)

Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Thu May 01 00:00:00 EDT 2014

Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.

Stem cells (Dayton, Ohio)

Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Thu May 01 00:00:00 EDT 2014

Bone marrow mesenchymal stem cells provide an antibiotic-protective niche for persistent viable Mycobacterium tuberculosis that survive antibiotic treatment.

The American journal of pathology

Beamer G,Major S,Das B,Campos-Neto A

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Dec 01 00:00:00 EST 2014

Identification of hematopoietic-specific regulatory elements from the CD45 gene and use for lentiviral tracking of transplanted cells.

Experimental hematology

Duong KL,Das S,Yu S,Barr JY,Jena S,Kim E,Zavazava N,Colgan JD,Xue HH,Levasseur DN

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Sep 01 00:00:00 EDT 2014

A new animal model of spontaneous autoimmune peripheral polyneuropathy: implications for Guillain-Barré syndrome.

Acta neuropathologica communications

Yang M,Rainone A,Shi XQ,Fournier S,Zhang J

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Jan 08 00:00:00 EST 2014

Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.

PloS one

Xiao GY,Liu IH,Cheng CC,Chang CC,Lee YH,Cheng WT,Wu SC

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu May 28 00:00:00 EDT 2015

Activation of NLRP3 inflammasome by crystalline structures via cell surface contact.

Scientific reports

Hari A,Zhang Y,Tu Z,Detampel P,Stenner M,Ganguly A,Shi Y

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Dec 02 00:00:00 EST 2014

The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation.

The Journal of biological chemistry

Eitas TK,Chou WC,Wen H,Gris D,Robbins GR,Brickey J,Oyama Y,Ting JP

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Feb 14 00:00:00 EST 2014

Canonical Wnt signaling promotes early hematopoietic progenitor formation and erythroid specification during embryonic stem cell differentiation.

PloS one

Tarafdar A,Dobbin E,Corrigan P,Freeburn R,Wheadon H

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunofluorescence

Tue Jul 29 00:00:00 EDT 2014

Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets.

PloS one

El-Zaatari M,Kao JY,Tessier A,Bai L,Hayes MM,Fontaine C,Eaton KA,Merchant JL

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Sep 10 00:00:00 EDT 2013

Tumorigenic cells are common in mouse MPNSTs but their frequency depends upon tumor genotype and assay conditions.

Cancer cell

Buchstaller J,McKeever PE,Morrison SJ

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Feb 14 00:00:00 EST 2012

Autophagy links inflammasomes to atherosclerotic progression.

Cell metabolism

Razani B,Feng C,Coleman T,Emanuel R,Wen H,Hwang S,Ting JP,Virgin HW,Kastan MB,Semenkovich CF

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunofluorescence

Wed Apr 04 00:00:00 EDT 2012

Etv2 is expressed in the yolk sac hematopoietic and endothelial progenitors and regulates Lmo2 gene expression.

Stem cells (Dayton, Ohio)

Koyano-Nakagawa N,Kweon J,Iacovino M,Shi X,Rasmussen TL,Borges L,Zirbes KM,Li T,Perlingeiro RC,Kyba M,Garry DJ

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Wed Aug 01 00:00:00 EDT 2012

Transgenic expression of interferon-γ in mouse stomach leads to inflammation, metaplasia, and dysplasia.

The American journal of pathology

Syu LJ,El-Zaatari M,Eaton KA,Liu Z,Tetarbe M,Keeley TM,Pero J,Ferris J,Wilbert D,Kaatz A,Zheng X,Qiao X,Grachtchouk M,Gumucio DL,Merchant JL,Samuelson LC,Dlugosz AA

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Sat Dec 01 00:00:00 EST 2012

A model of GAG/MIP-2/CXCR2 interfaces and its functional effects.

Biochemistry

Rajasekaran D,Keeler C,Syed MA,Jones MC,Harrison JK,Wu D,Bhandari V,Hodsdon ME,Lolis EJ

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Jul 17 00:00:00 EDT 2012

Delta-like ligand (DLL)1 expression in early mouse decidua and its localization to uterine natural killer cells.

PloS one

Degaki KY,Chen Z,Yamada AT,Croy BA

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunofluorescence

Tue Jun 25 00:00:00 EDT 2013

Cell type-associated differences in migration, survival, and immunogenicity following grafting in CNS tissue.

Cell transplantation

Praet J,Reekmans K,Lin D,De Vocht N,Bergwerf I,Tambuyzer B,Daans J,Hens N,Goossens H,Pauwels P,Berneman Z,Van der Linden A,Ponsaerts P

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Dec 06 00:00:00 EST 2013

ER71 directs mesodermal fate decisions during embryogenesis.

Development (Cambridge, England)

Rasmussen TL,Kweon J,Diekmann MA,Belema-Bedada F,Song Q,Bowlin K,Shi X,Ferdous A,Li T,Kyba M,Metzger JM,Koyano-Nakagawa N,Garry DJ

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Nov 01 00:00:00 EDT 2011

The anti-tumor effect of resveratrol alone or in combination with immunotherapy in a neuroblastoma model.

Cancer immunology, immunotherapy : CII

Soto BL,Hank JA,Van De Voort TJ,Subramanian L,Polans AS,Rakhmilevich AL,Yang RK,Seo S,Kim K,Reisfeld RA,Gillies SD,Sondel PM

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunohistochemistry

Sun May 01 00:00:00 EDT 2011

Effect of topical azithromycin on corneal innate immune responses.

Investigative ophthalmology & visual science

Sadrai Z,Hajrasouliha AR,Chauhan S,Saban DR,Dastjerdi MH,Dana R

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Tue Apr 19 00:00:00 EDT 2011

Myeloid cells migrate in response to IL-24.

Cytokine

Buzas K,Oppenheim JJ,Zack Howard OM

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Thu Sep 01 00:00:00 EDT 2011

Clinical potential of intravenous neural stem cell delivery for treatment of neuroinflammatory disease in mice?

Cell transplantation

Reekmans KP,Praet J,De Vocht N,Tambuyzer BR,Bergwerf I,Daans J,Baekelandt V,Vanhoutte G,Goossens H,Jorens PG,Ysebaert DK,Chatterjee S,Pauwels P,Van Marck E,Berneman ZN,Van der Linden A,Ponsaerts P

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Fri Dec 09 00:00:00 EST 2011

Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development.

Hepatology (Baltimore, Md.)

Asahina K,Tsai SY,Li P,Ishii M,Maxson RE,Sucov HM,Tsukamoto H

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunofluorescence

Sun Mar 01 00:00:00 EST 2009

Involvement of IQGAP3, a regulator of Ras/ERK-related cascade, in hepatocyte proliferation in mouse liver regeneration and development.

Journal of cellular physiology

Kunimoto K,Nojima H,Yamazaki Y,Yoshikawa T,Okanoue T,Tsukita S

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Immunofluorescence

Tue Sep 01 00:00:00 EDT 2009

Optimized isolation enables ex vivo analysis of microglia from various central nervous system regions.

Glia

de Haas AH,Boddeke HW,Brouwer N,Biber K

Published figure using CD45 monoclonal antibody (Product # 69-0451-82) in Flow Cytometry

Mon Oct 01 00:00:00 EDT 2007

Bioinformatics

Protein Aliases: CD45; L-CA; Leukocyte common antigen; Ly-5; Lymphocyte antigen 5; lymphocyte common antigen; Receptor-type tyrosine-protein phosphatase C; T200; T220 and B220

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Gene Aliases: B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4; Ptprc; T200

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UniProt ID: (Mouse) P06800

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Entrez Gene ID: (Mouse) 19264

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Function(s)

phosphoprotein phosphatase activity protein tyrosine phosphatase activity protein binding heparin binding hydrolase activity phosphatase activity protein kinase binding heparan sulfate proteoglycan binding protein phosphatase protein modifying enzyme

Process(es)

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CD45 Monoclonal Antibody (30-F11), eFluor™ 506, eBioscience™

CD45 Antibody (69-0451-82) in Flow

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69-0451-82

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