Product References
Cissus quadrangularis (Hadjod) Inhibits RANKL-Induced Osteoclastogenesis and Augments Bone Health in an Estrogen-Deficient Preclinical Model of Osteoporosis Via Modulating the Host Osteoimmune System.
Cells
Azam Z,Sapra L,Baghel K,Sinha N,Gupta RK,Soni V,Saini C,Mishra PK,Srivastava RK
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Wed Jan 04 00:00:00 EST 2023
Profiling Germinal Center-like B Cell Responses to Conjugate Vaccines Using Synthetic Immune Organoids.
ACS central science
Moeller TD,Shah SB,Lai K,Lopez-Barbosa N,Desai P,Wang W,Zhong Z,Redmond D,Singh A,DeLisa MP
25-0193-82 was used in Flow cytometry/Cell sorting to highlight the potential of synthetic organoids for rapidly predicting conjugate vaccine efficacy as well as expediting antigen-specific antibody discovery.
Wed Apr 26 00:00:00 EDT 2023
Role of FGF10/FGFR2b Signaling in Homeostasis and Regeneration of Adult Lacrimal Gland and Corneal Epithelium Proliferation.
Investigative ophthalmology & visual science
Finburgh EN,Mauduit O,Noguchi T,Bu JJ,Abbas AA,Hakim DF,Bellusci S,Meech R,Makarenkova HP,Afshari NA
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Tue Jan 03 00:00:00 EST 2023
Altered B cell immunoglobulin signature exhibits potential diagnostic values in human colorectal cancer.
iScience
Liu RX,Wen C,Ye W,Li Y,Chen J,Zhang Q,Li W,Liang W,Wei L,Zhang J,Chan KW,Wang X,Yang X,Liu H
25-0193-82 was used in Flow cytometry/Cell sorting to compare the altered plasma immunoglobulin signature with the existing method of CRC diagnosis.
Fri Mar 17 00:00:00 EDT 2023
TCR repertoire landscape reveals macrophage-mediated clone deletion in endotoxin tolerance.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Zhao J,Jia L,Tao Y,Zhao X,Yang J,Lu Y,Yan Y,Mao L,Hu L,Lu J,Guo M,Chen C,Zhou Y,Wen Z,He Z,Xu L
25-0193-82 was used in Flow cytometry/Cell sorting to suggest that the clone selection in thymus in Endotoxin tolerance may confer protection against microbial sepsis.
Wed Mar 01 00:00:00 EST 2023
Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation.
Cancer discovery
Chen S,Vedula RS,Cuevas-Navarro A,Lu B,Hogg SJ,Wang E,Benbarche S,Knorr K,Kim WJ,Stanley RF,Cho H,Erickson C,Singer M,Cui D,Tittley S,Durham BH,Pavletich TS,Fiala E,Walsh MF,Inoue D,Monette S,Taylor J,Rosen N,McCormick F,Lindsley RC,Castel P,Abdel-Wahab O
25-0193-82 was used in Flow cytometry/Cell sorting to reveal proteolysis of non-canonical RAS proteins as novel regulators of HSC self-renewal, define the function of RIT1 and LZTR1 mutations in leukemia, and identify means to overcome drug resistance due to LZTR1 downregulation.
Wed Oct 05 00:00:00 EDT 2022
Caspase-8 auto-cleavage regulates programmed cell death and collaborates with RIPK3/MLKL to prevent lymphopenia.
Cell death and differentiation
Li X,Li F,Zhang X,Zhang H,Zhao Q,Li M,Wu X,Wang L,Liu J,Wu X,Ou Y,Xing M,Zhang Y,Deng J,Wang X,Luo Y,Li J,Zhao Y,Zhang H
25-0193-82 was used in Flow Cytometry to demonstrate previously unappreciated roles for caspase-8 auto-cleavage in regulating necroptosis and maintaining lymphocytes homeostasis.
Mon Aug 01 00:00:00 EDT 2022
Valosin-containing protein (VCP/p97) inhibition reduces viral clearance and induces toxicity associated with muscular damage.
Cell death & disease
Del Rio Oliva M,Basler M
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
NUDT21 limits CD19 levels through alternative mRNA polyadenylation in B cell acute lymphoblastic leukemia.
Nature immunology
Witkowski MT,Lee S,Wang E,Lee AK,Talbot A,Ma C,Tsopoulidis N,Brumbaugh J,Zhao Y,Roberts KG,Hogg SJ,Nomikou S,Ghebrechristos YE,Thandapani P,Mullighan CG,Hochedlinger K,Chen W,Abdel-Wahab O,Eyquem J,Aifantis I
25-0193-82 was used in Flow cytometry/Cell sorting to identify new CD19 modulators in human B-ALL.
Sat Oct 01 00:00:00 EDT 2022
High-yield enrichment of mouse small intestine intraepithelial lymphocytes by immunomagnetic depletion of EpCAM+ cells.
STAR protocols
Prakhar P,Gonzalez V,Park JH
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Fri Mar 18 00:00:00 EDT 2022
Polysome-CAGE of TCL1-driven chronic lymphocytic leukemia revealed multiple N-terminally altered epigenetic regulators and a translation stress signature.
eLife
Ogran A,Havkin-Solomon T,Becker-Herman S,David K,Shachar I,Dikstein R
25-0193-82 was used in Flow cytometry/Cell sorting to uncover the role of Tcl1 oncogenic function in altering promoter usage and mRNA translation in leukemogenesis.
Mon Aug 08 00:00:00 EDT 2022
Monocarboxylate transporter 1 deficiency impacts CD8+ T lymphocytes proliferation and recruitment to adipose tissue during obesity.
iScience
Macchi C,Moregola A,Greco MF,Svecla M,Bonacina F,Dhup S,Dadhich RK,Audano M,Sonveaux P,Mauro C,Mitro N,Ruscica M,Norata GD
25-0193-82 was used in Flow cytometry/Cell sorting to highlight a distinct effect of MCT1 deficiency in CD8+ T cells in the crosstalk with adipocytes and reinforce the concept that targeting immunometabolic reprogramming in lymphocyte could impact the immune-adipose tissue axis in obesity.
Fri Jun 17 00:00:00 EDT 2022
The ubiquitin ligase Peli1 inhibits ICOS and thereby Tfh-mediated immunity.
Cellular & molecular immunology
Huang X,Hao S,Liu J,Huang Y,Liu M,Xiao C,Wang Y,Pei S,Yu T,Xu J,Wang H,Dai D,Su X,Xiao Y
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Functional human IgA targets a conserved site on malaria sporozoites.
Science translational medicine
Tan J,Cho H,Pholcharee T,Pereira LS,Doumbo S,Doumtabe D,Flynn BJ,Schön A,Kanatani S,Aylor SO,Oyen D,Vistein R,Wang L,Dillon M,Skinner J,Peterson M,Li S,Idris AH,Molina-Cruz A,Zhao M,Olano LR,Lee PJ,Roth A,Sinnis P,Barillas-Mury C,Kayentao K,Ongoiba A,Francica JR,Traore B,Wilson IA,Seder RA,Crompton PD
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Wed Jun 23 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
The Journal of experimental medicine
Ho TT,Dellorusso PV,Verovskaya EV,Bakker ST,Flach J,Smith LK,Ventura PB,Lansinger OM,Hérault A,Zhang SY,Kang YA,Mitchell CA,Villeda SA,Passegué E
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
In Vivo HSC Gene Therapy Using a Bi-modular HDAd5/35++ Vector Cures Sickle Cell Disease in a Mouse Model.
Molecular therapy : the journal of the American Society of Gene Therapy
Li C,Wang H,Georgakopoulou A,Gil S,Yannaki E,Lieber A
25-0193-82 was used in Flow Cytometry to report that, after in vivo hematopoietic stem cell/progenitor (HSPC) transduction with HDAd5/35++ vectors, SB100x transposase-mediated γ-globin gene addition achieved 10%-15% γ-globin of adult mouse globin, resulting in significant but incomplete phenotypic correction in a thalassemia intermedia mouse model.
Wed Feb 03 00:00:00 EST 2021
The gammaherpesvirus 68 viral cyclin facilitates expression of LANA.
PLoS pathogens
Niemeyer BF,Sanford B,Gibson JE,Berger JN,Oko LM,Medina E,Clambey ET,van Dyk LF
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
Regulatory B Cells (Bregs) Inhibit Osteoclastogenesis and Play a Potential Role in Ameliorating Ovariectomy-Induced Bone Loss.
Frontiers in immunology
Sapra L,Bhardwaj A,Mishra PK,Garg B,Verma B,Mishra GC,Srivastava RK
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Thu Nov 04 00:00:00 EDT 2021
Comprehensive mutagenesis identifies the peptide repertoire of a p53 T-cell receptor mimic antibody that displays no toxicity in mice transgenic for human HLA-A*0201.
PloS one
Trenevska I,Anderson AP,Bentley C,Hassanali T,Wiblin S,Maguire S,Pezzella F,Banham AH,Li D
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Wed Sep 29 00:00:00 EDT 2021
CCL17-expressing dendritic cells in the intestine are preferentially infected by Salmonella but CCL17 plays a redundant role in systemic dissemination.
Immunity, inflammation and disease
Erazo AB,Wang N,Standke L,Semeniuk AD,Fülle L,Cengiz SC,Thiem M,Weighardt H,Strugnell RA,Förster I
25-0193-82 was used in Flow Cytometry to study the role of CCL17 during the early phase of infection, including bacterial spreading from the intestine to the draining lymph nodes.
Wed Sep 01 00:00:00 EDT 2021
Myeloid cell subsets that express latency-associated peptide promote cancer growth by modulating T cells.
iScience
Gabriely G,Ma D,Siddiqui S,Sun L,Skillin NP,Abou-El-Hassan H,Moreira TG,Donnelly D,da Cunha AP,Fujiwara M,Walton LR,Patel A,Krishnan R,Levine SS,Healy BC,Rezende RM,Murugaiyan G,Weiner HL
25-0193-82 was used in Flow cytometry/Cell sorting to identify a previously unknown function by which LAPHi MCs promote tumor growth and offer therapeutic intervention to target these cells in cancer.
Fri Nov 19 00:00:00 EST 2021
The concerted change in the distribution of cell cycle phases and zone composition in germinal centers is regulated by IL-21.
Nature communications
Zotos D,Quast I,Li-Wai-Suen CSN,McKenzie CI,Robinson MJ,Kan A,Smyth GK,Hodgkin PD,Tarlinton DM
25-0193-82 was used in Flow Cytometry to investigate regulation of cell cycle and germinal centres.
Thu Dec 09 00:00:00 EST 2021
Expanded renal lymphatics improve recovery following kidney injury.
Physiological reports
Baranwal G,Creed HA,Black LM,Auger A,Quach AM,Vegiraju R,Eckenrode HE,Agarwal A,Rutkowski JM
25-0193-82 was used in Flow cytometry/Cell sorting to demonstrate that increased lymphatic density prior to injury alters the injury recovery response and affords protection from CKD progression.
Mon Nov 01 00:00:00 EDT 2021
ILC3s control airway inflammation by limiting T cell responses to allergens and microbes.
Cell reports
Teng F,Tachó-Piñot R,Sung B,Farber DL,Worgall S,Hammad H,Lambrecht BN,Hepworth MR,Sonnenberg GF
25-0193-82 was used in Flow cytometry/Cell sorting to demonstrate a critical role for antigen-presenting ILC3s in orchestrating immune tolerance in the airway by restricting pro-inflammatory T cell responses to both allergens and microbes.
Tue Nov 23 00:00:00 EST 2021
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist.
eLife
Glassman CR,Su L,Majri-Morrison SS,Winkelmann H,Mo F,Li P,Pérez-Cruz M,Ho PP,Koliesnik I,Nagy N,Hnizdilova T,Picton LK,Kovar M,Bollyky P,Steinman L,Meyer E,Piehler J,Leonard WJ,Garcia KC
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Tue May 18 00:00:00 EDT 2021
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist.
eLife
Glassman CR,Su L,Majri-Morrison SS,Winkelmann H,Mo F,Li P,Pérez-Cruz M,Ho PP,Koliesnik I,Nagy N,Hnizdilova T,Picton LK,Kovar M,Bollyky P,Steinman L,Meyer E,Piehler J,Leonard WJ,Garcia KC
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Tue May 18 00:00:00 EDT 2021
Astrocytic trans-Differentiation Completes a Multicellular Paracrine Feedback Loop Required for Medulloblastoma Tumor Growth.
Cell
Yao M,Ventura PB,Jiang Y,Rodriguez FJ,Wang L,Perry JSA,Yang Y,Wahl K,Crittenden RB,Bennett ML,Qi L,Gong CC,Li XN,Barres BA,Bender TP,Ravichandran KS,Janes KA,Eberhart CG,Zong H
25-0193 was used in Flow cytometry/Cell sorting to reveal an evolutionary process that produces a multi-lateral network within the TME of medulloblastoma: a fraction of tumor cells trans-differentiate into TuAstrocytes, which, in turn, produce IL-4 that stimulates microglia to produce IGF1 to promote tumor progression.
Thu Feb 06 00:00:00 EST 2020
C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor.
Cancer cell
Di Genua C,Valletta S,Buono M,Stoilova B,Sweeney C,Rodriguez-Meira A,Grover A,Drissen R,Meng Y,Beveridge R,Aboukhalil Z,Karamitros D,Belderbos ME,Bystrykh L,Thongjuea S,Vyas P,Nerlov C
25-0193 was used in Flow cytometry/Cell sorting to show that combined biallelic Cebpa and Gata2 zinc finger-1 (ZnF1) mutations cooperatively induce bilineage AEL, and that the major leukemia-initiating cell (LIC) population has a neutrophil-monocyte progenitor (NMP) phenotype.
Mon May 11 00:00:00 EDT 2020
Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection.
Nature immunology
Aegerter H,Kulikauskaite J,Crotta S,Patel H,Kelly G,Hessel EM,Mack M,Beinke S,Wack A
25-0193 was used in Flow cytometry/Cell sorting to help to understand how transient respiratory infections, a common occurrence in human life, can constantly alter lung immunity by contributing monocyte-derived, recruited cells to the AM population.
Sat Feb 01 00:00:00 EST 2020
Excessive Costimulation Leads to Dysfunction of Adoptively Transferred T Cells.
Cancer immunology research
Wijewarnasuriya D,Bebernitz C,Lopez AV,Rafiq S,Brentjens RJ
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2020
DKK2 blockage-mediated immunotherapy enhances anti-angiogenic therapy of Kras mutated colorectal cancer.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hu J,Wang Z,Chen Z,Li A,Sun J,Zheng M,Wu J,Shen T,Qiao J,Li L,Li B,Wu D,Xiao Q
25-0193-82 was used in Flow Cytometry to demonstrate that if in human colorectal cancer tumor samples expressing high levels of DKK2, DKK2 blockade cause stronger activation of tumor infiltrating CD8+ T cells in ex vivo culture.
Wed Jul 01 00:00:00 EDT 2020
Novel enhanced GFP-positive congenic inbred strain establishment and application of tumor-bearing nude mouse model.
Cancer science
Lan Q,Chen Y,Dai C,Li S,Fei X,Dong J,Shen Y,Dai X,Lu Z,Liu B,Wang Q,Wang H,Zhou Z,Ji X,Wang Z,Huang Q
25-0193 was used in Flow cytometry/Cell sorting to demonstrate that host cell malignant transformation and tumor/host cell fusion play an important role in tumor progression.
Thu Oct 01 00:00:00 EDT 2020
Differentiation Potential of Early- and Late-Passage Adipose-Derived Mesenchymal Stem Cells Cultured under Hypoxia and Normoxia.
Stem cells international
Zhao AG,Shah K,Freitag J,Cromer B,Sumer H
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Tue Oct 06 00:00:00 EDT 2020
Differentiation Potential of Early- and Late-Passage Adipose-Derived Mesenchymal Stem Cells Cultured under Hypoxia and Normoxia.
Stem cells international
Zhao AG,Shah K,Freitag J,Cromer B,Sumer H
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Tue Oct 06 00:00:00 EDT 2020
Zdhhc2 Is Essential for Plasmacytoid Dendritic Cells Mediated Inflammatory Response in Psoriasis.
Frontiers in immunology
Zhou B,Yang W,Li W,He L,Lu L,Zhang L,Liu Z,Wang Y,Chao T,Huang R,Gu Y,Jia T,Liu Q,Tian S,Pierre P,Maeda T,Liang Y,Kong E
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Wed Jun 23 00:00:00 EDT 2021
CNS Immune Profiling in a Dengue Virus-Infected Immunocompetent Outbred ICR Mice Strain.
Frontiers in cellular and infection microbiology
Shen TJ,Chen CL,Jhan MK,Tseng PC,Lin CF
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Thu Jun 17 00:00:00 EDT 2021
miR-29 Sustains B Cell Survival and Controls Terminal Differentiation via Regulation of PI3K Signaling.
Cell reports
Hines MJ,Coffre M,Mudianto T,Panduro M,Wigton EJ,Tegla C,Osorio-Vasquez V,Kageyama R,Benhamou D,Perez O,Bajwa S,McManus MT,Ansel KM,Melamed D,Koralov SB
25-0193 was used in Flow cytometry/Cell sorting to suggest a critical role for the miR-29-PTEN-PI3K regulatory axis in mature B lymphocytes.
Tue Dec 01 00:00:00 EST 2020
Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection.
Cell reports
Cham LB,Torrez Dulgeroff LB,Tal MC,Adomati T,Li F,Bhat H,Huang A,Lang PA,Moreno ME,Rivera JM,Galkina SA,Kosikova G,Stoddart CA,McCune JM,Myers LM,Weissman IL,Lang KS,Hasenkrug KJ
25-0193 was used in Flow cytometry/Cell sorting to indicate that CD47 blockade not only enhances the function of innate immune cells but also links to adaptive immune responses through improved APC function.
Tue Apr 14 00:00:00 EDT 2020
Memory CD73+IgM+ B cells protect against Plasmodium yoelii infection and express Granzyme B.
PloS one
Parra M,Weitner M,Yang A,Akue A,Liu X,Schmidt T,Allman WR,Akkoyunlu M,Derrick SC
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Tue Oct 27 00:00:00 EDT 2020
Curative in vivo hematopoietic stem cell gene therapy of murine thalassemia using large regulatory elements.
JCI insight
Wang H,Georgakopoulou A,Li C,Liu Z,Gil S,Bashyam A,Yannaki E,Anagnostopoulos A,Pande A,Izsvák Z,Papayannopoulou T,Lieber A
25-0193 was used in Flow cytometry/Cell sorting to demonstrate that hematopoietic stem/progenitor cell (HSPC) mobilization followed by intravenous injection of integrating, helper-dependent adenovirus HDAd5/35++ vectors resulted in efficient transduction of long-term repopulating cells and disease amelioration in mouse models after in vivo selection of transduced HSPCs.
Thu Aug 20 00:00:00 EDT 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Fri Jun 19 00:00:00 EDT 2020
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Mon Jun 29 00:00:00 EDT 2020
Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity.
Cell
Brown CC,Gudjonson H,Pritykin Y,Deep D,Lavallée VP,Mendoza A,Fromme R,Mazutis L,Ariyan C,Leslie C,Pe'er D,Rudensky AY
25-0193 was used in Flow cytometry/Cell sorting to identify two principal cDC2 lineages defined by distinct developmental pathways and transcriptional regulators, including T-bet and RORγt, two key transcription factors known to define innate and adaptive lymphocyte subsets.
Thu Oct 31 00:00:00 EDT 2019
Polychromic Reporter Mice Reveal Unappreciated Innate Lymphoid Cell Progenitor Heterogeneity and Elusive ILC3 Progenitors in Bone Marrow.
Immunity
Walker JA,Clark PA,Crisp A,Barlow JL,Szeto A,Ferreira ACF,Rana BMJ,Jolin HE,Rodriguez-Rodriguez N,Sivasubramaniam M,Pannell R,Cruickshank J,Daly M,Haim-Vilmovsky L,Teichmann SA,McKenzie ANJ
25-0193 was used in Flow cytometry/Cell sorting to identify a discrete ILC2-committed population and delineated transition states between early progenitors and a highly heterogeneous ILC1, ILC3, and NK precursor cell cluster.
Tue Jul 16 00:00:00 EDT 2019
Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting.
Cancer cell
Srivastava S,Salter AI,Liggitt D,Yechan-Gunja S,Sarvothama M,Cooper K,Smythe KS,Dudakov JA,Pierce RH,Rader C,Riddell SR
25-0193 was used in Flow cytometry/Cell sorting to demonstrate the use of “AND” logic gates as a strategy to increase the portfolio of cell surface molecules on solid tumors that can be targeted safely with CAR-T cells.
Mon Mar 18 00:00:00 EDT 2019
Formyl peptide receptor 2 regulates monocyte recruitment to promote intestinal mucosal wound repair.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Birkl D,O'Leary MN,Quiros M,Azcutia V,Schaller M,Reed M,Nishio H,Keeney J,Neish AS,Lukacs NW,Parkos CA,Nusrat A
25-0193-82 was used in Flow Cytometry to study how Fpr2/3 regulates CCL20-CCR6-mediated monocyte chemotaxis to sites of mucosal injury in the gut to influence wound repair.
Sun Dec 01 00:00:00 EST 2019
Peritoneal Cells Mediate Immune Responses and Cross-Protection Against Influenza A Virus.
Frontiers in immunology
Gautam A,Park BK,Kim TH,Akauliya M,Kim D,Maharjan S,Park J,Kim J,Lee H,Park MS,Lee Y,Kwon HJ
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Mon Aug 17 00:00:00 EDT 2020
Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus.
Scientific reports
Goldstein JM,Valido A,Lewandowski JP,Walker RG,Mills MJ,Messemer KA,Besseling P,Lee KH,Wattrus SJ,Cho M,Lee RT,Wagers AJ
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Mon Dec 09 00:00:00 EST 2019
ImmGen report: sexual dimorphism in the immune system transcriptome.
Nature communications
Gal-Oz ST,Maier B,Yoshida H,Seddu K,Elbaz N,Czysz C,Zuk O,Stranger BE,Ner-Gaon H,Shay T
25-0193 was used in Flow cytometry/Cell sorting to show transcriptional sexual dimorphism in macrophages.
Fri Sep 20 00:00:00 EDT 2019
Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp.
Nature communications
Cheng HW,Onder L,Novkovic M,Soneson C,Lütge M,Pikor N,Scandella E,Robinson MD,Miyazaki JI,Tersteegen A,Sorg U,Pfeffer K,Rülicke T,Hehlgans T,Ludewig B
25-0193 was used in Flow cytometry/Cell sorting to establish fibroblastic reticular cell (FRC)- specific fate-mapping in mice to identify the embryonic origin and differentiation trajectories in the splenic white pulp.
Mon Apr 15 00:00:00 EDT 2019
Glucose lowering by SGLT2-inhibitor empagliflozin accelerates atherosclerosis regression in hyperglycemic STZ-diabetic mice.
Scientific reports
Pennig J,Scherrer P,Gissler MC,Anto-Michel N,Hoppe N,Füner L,Härdtner C,Stachon P,Wolf D,Hilgendorf I,Mullick A,Bode C,Zirlik A,Goldberg IJ,Willecke F
25-0193 was used in Flow cytometry/Cell sorting to determine whether glucose lowering by empagliflozin accelerates atherosclerosis regression in a mouse model.
Fri Nov 29 00:00:00 EST 2019
Activated Peyer's patch B cells sample antigen directly from M cells in the subepithelial dome.
Nature communications
Komban RJ,Strömberg A,Biram A,Cervin J,Lebrero-Fernández C,Mabbott N,Yrlid U,Shulman Z,Bemark M,Lycke N
25-0193-82 was used in Flow Cytometry to report a M cell-B cell antigen-specific transporting pathway in PP that is independent of DC. We propose that this antigen transporting pathway has a critical role in gut IgA responses, and should be taken into account when developing mucosal vaccines.
Mon Jun 03 00:00:00 EDT 2019
DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune-cell activation.
Nature medicine
Xiao Q,Wu J,Wang WJ,Chen S,Zheng Y,Yu X,Meeth K,Sahraei M,Bothwell ALM,Chen L,Bosenberg M,Chen J,Sexl V,Sun L,Li L,Tang W,Wu D
25-0193 was used in Flow cytometry/Cell sorting to identify a novel tumour immune-suppressive mechanism and immunotherapeutic targets particularly relevant for colorectal cancers and a subset of melanomas.
Thu Mar 01 00:00:00 EST 2018
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.
Immunity
Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC
25-0193 was used in Flow Cytometry to indicate that the VHL-HIF-glycolysis axis is essential for the late-stage maturation and function of ILC2s via targeting IL-33-ST2 pathway.
Tue Feb 20 00:00:00 EST 2018
Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations.
Cancer cell
Lee SC,North K,Kim E,Jang E,Obeng E,Lu SX,Liu B,Inoue D,Yoshimi A,Ki M,Yeo M,Zhang XJ,Kim MK,Cho H,Chung YR,Taylor J,Durham BH,Kim YJ,Pastore A,Monette S,Palacino J,Seiler M,Buonamici S,Smith PG,Ebert BL,Bradley RK,Abdel-Wahab O
25-0193 was used in Flow cytometry/Cell sorting to identify shared consequences of splicing-factor mutations and the basis for their mutual exclusivity.
Mon Aug 13 00:00:00 EDT 2018
TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis.
Cancer discovery
Dominguez PM,Ghamlouch H,Rosikiewicz W,Kumar P,Béguelin W,Fontán L,Rivas MA,Pawlikowska P,Armand M,Mouly E,Torres-Martin M,Doane AS,Calvo Fernandez MT,Durant M,Della-Valle V,Teater M,Cimmino L,Droin N,Tadros S,Motanagh S,Shih AH,Rubin MA,Tam W,Aifantis I,Levine RL,Elemento O,Inghirami G,Green MR,Figueroa ME,Bernard OA,Aoufouchi S,Li S,Shaknovich R,Melnick AM
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2018
11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis.
Journal of autoimmunity
Hardy RS,Fenton C,Croft AP,Naylor AJ,Begum R,Desanti G,Buckley CD,Lavery G,Cooper MS,Raza K
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Wed Aug 01 00:00:00 EDT 2018
Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Wang Y,Xiao M,Tao C,Chen J,Wang Z,Yang J,Chen Z,Zou Z,Liu A,Cai D,Jiang Y,Ding C,Li M,Bai X
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
The Role of Allograft Inflammatory Factor-1 in the Effects of Experimental Diabetes on B Cell Functions in the Heart.
Frontiers in cardiovascular medicine
Sarkar A,Shukla SK,Alqatawni A,Kumar A,Addya S,Tsygankov AY,Rafiq K
25-0193 was used in Flow cytometry/Cell sorting to assess the role of allograft inflammatory factor-1 in the effects of experimental diabetes on B cell functions in the heart.
Mon Dec 06 00:00:00 EST 2021
Regulation of Intracellular Triiodothyronine Is Essential for Optimal Macrophage Function.
Endocrinology
van der Spek AH,Surovtseva OV,Jim KK,van Oudenaren A,Brouwer MC,Vandenbroucke-Grauls CMJE,Leenen PJM,van de Beek D,Hernandez A,Fliers E,Boelen A
25-0193 was used in Flow cytometry/Cell sorting to study the role of optimal intracellular concentrations of the active thyroid hormone triiodothyronine in proinflammatory macrophage function.
Tue May 01 00:00:00 EDT 2018
The Thyroid Hormone Inactivating Type 3 Deiodinase Is Essential for Optimal Neutrophil Function: Observations From Three Species.
Endocrinology
van der Spek AH,Jim KK,Karaczyn A,van Beeren HC,Ackermans MT,Darras VM,Vandenbroucke-Grauls CMJE,Hernandez A,Brouwer MC,Fliers E,van de Beek D,Boelen A
25-0193 was used in Flow cytometry/Cell sorting to study whether type 3 deiodinase plays a role in neutrophil function during infection.
Thu Feb 01 00:00:00 EST 2018
In Vitro Differentiation of Gata2 and Ly6a Reporter Embryonic Stem Cells Corresponds to In Vivo Waves of Hematopoietic Cell Generation.
Stem cell reports
Kauts ML,Rodriguez-Seoane C,Kaimakis P,Mendes SC,Cortés-Lavaud X,Hill U,Dzierzak E
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Tue Jan 09 00:00:00 EST 2018
Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus.
Nature communications
Liu J,Huang X,Hao S,Wang Y,Liu M,Xu J,Zhang X,Yu T,Gan S,Dai D,Luo X,Lu Q,Mao C,Zhang Y,Shen N,Li B,Huang M,Zhu X,Jin J,Cheng X,Sun SC,Xiao Y
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Mon Mar 19 00:00:00 EDT 2018
Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
eLife
Moretti FA,Klapproth S,Ruppert R,Margraf A,Weber J,Pick R,Scheiermann C,Sperandio M,Fässler R,Moser M
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
A protocol for generating induced T cells by reprogramming B cells in vivo.
Cell regeneration (London, England)
Weng Q,Hu F,Zhang M,Dong Y,Lv C,Wang Y,Liu X,Wang J
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
A mouse model for evaluation of efficacy and concomitant toxicity of anti-human CXCR4 therapeutics.
PloS one
Costa MJ,Kudaravalli J,Liu WH,Stock J,Kong S,Liu SH
25-0193 was used in Flow cytometry/Cell sorting to describe the generation and validation of the first mouse knock-in of the whole coding region of human CXCR4.
Mon Jul 23 00:00:00 EDT 2018
A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors.
Nature communications
Vigolo M,Chambers MG,Willen L,Chevalley D,Maskos K,Lammens A,Tardivel A,Das D,Kowalczyk-Quintas C,Schuepbach-Mallepell S,Smulski CR,Eslami M,Rolink A,Hummler E,Samy E,Fomekong Nanfack Y,Mackay F,Liao M,Hess H,Jiang X,Schneider P
25-0193 was used in Flow cytometry/Cell sorting to study TNSF13B/BAFF interactions in C57BL/6OlaHsd mice. TNSF13B/BAFF underwent flow cytometry to investigate if distint biological and clinical efficacies occur to the therapeutically relevant inhibitors.
Fri Mar 23 00:00:00 EDT 2018
ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases.
Frontiers in immunology
Glal D,Sudhakar JN,Lu HH,Liu MC,Chiang HY,Liu YC,Cheng CF,Shui JW
25-0193 was used in Flow cytometry/Cell sorting to identify the mechanism by which activating transcription factor 3 mediates a cross-regulation in the barrier to maintain mucosal homeostasis and immunity.
Thu Sep 26 00:00:00 EDT 2019
A therapeutic T cell receptor mimic antibody targets tumor-associated PRAME peptide/HLA-I antigens.
The Journal of clinical investigation
Chang AY,Dao T,Gejman RS,Jarvis CA,Scott A,Dubrovsky L,Mathias MD,Korontsvit T,Zakhaleva V,Curcio M,Hendrickson RC,Liu C,Scheinberg DA
25-0193 was used in Flow cytometry/Cell sorting to investigate the effect of Pr20 on cancer.
Fri Jun 30 00:00:00 EDT 2017
Upregulation of FcγRIIB by resveratrol via NF-κB activation reduces B-cell numbers and ameliorates lupus.
Experimental & molecular medicine
Jhou JP,Chen SJ,Huang HY,Lin WW,Huang DY,Tzeng SJ
25-0193 was used in Flow cytometry/Cell sorting to investigate whether resveratrol can alleviate lupus through FcγRIIB.
Fri Sep 29 00:00:00 EDT 2017
Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells.
Frontiers in immunology
Bai WJ,Li CG,Zhang CC,Xu LH,Zeng QZ,Hu B,Hong Z,He XH,Ouyang DY
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.
RNA biology
Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Thu May 04 00:00:00 EDT 2017
Diminished bone regeneration after debridement of posttraumatic osteomyelitis is accompanied by altered cytokine levels, elevated B cell activity, and increased osteoclast activity.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Wagner JM,Jaurich H,Wallner C,Abraham S,Becerikli M,Dadras M,Harati K,Duhan V,Khairnar V,Lehnhardt M,Behr B
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Wed Nov 01 00:00:00 EDT 2017
Role of Prolactin in Promotion of Immune Cell Migration into the Mammary Gland.
Journal of mammary gland biology and neoplasia
Dill R,Walker AM
25-0193 was used in Flow cytometry/Cell sorting to investigate the role of prolactin in immune cell recruitment.
Wed Mar 01 00:00:00 EST 2017
Intravenously usable fully serotype 3 oncolytic adenovirus coding for CD40L as an enabler of dendritic cell therapy.
Oncoimmunology
Zafar S,Parviainen S,Siurala M,Hemminki O,Havunen R,Tähtinen S,Bramante S,Vassilev L,Wang H,Lieber A,Hemmi S,de Gruijl T,Kanerva A,Hemminki A
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
NFAT2 is a critical regulator of the anergic phenotype in chronic lymphocytic leukaemia.
Nature communications
Märklin M,Heitmann JS,Fuchs AR,Truckenmüller FM,Gutknecht M,Bugl S,Saur SJ,Lazarus J,Kohlhofer U,Quintanilla-Martinez L,Rammensee HG,Salih HR,Kopp HG,Haap M,Kirschniak A,Kanz L,Rao A,Wirths S,Müller MR
25-0193 was used in Flow cytometry/Cell sorting to identify NFAT2 as a crucial regulator of the anergic phenotype in chronic lymphocytic leukaemia.
Mon Oct 02 00:00:00 EDT 2017
Distinct Kinase-Independent Role of RIPK3 in CD11c+ Mononuclear Phagocytes in Cytokine-Induced Tissue Repair.
Cell reports
Moriwaki K,Balaji S,Bertin J,Gough PJ,Chan FK
25-0193 was used in Flow cytometry/Cell sorting to study the distinct kinase-independent role of RIPK3 in cytokine-induced tissue repair.
Tue Mar 07 00:00:00 EST 2017
Genetic lineage tracing identifies in situ Kit-expressing cardiomyocytes.
Cell research
Liu Q,Yang R,Huang X,Zhang H,He L,Zhang L,Tian X,Nie Y,Hu S,Yan Y,Zhang L,Qiao Z,Wang QD,Lui KO,Zhou B
25-0193 was used in Flow cytometry/Cell sorting to show that genetic lineage tracing can identify in-situ Kit expressing cardiomyocytes.
Fri Jan 01 00:00:00 EST 2016
IL35-Producing B Cells Promote the Development of Pancreatic Neoplasia.
Cancer discovery
Pylayeva-Gupta Y,Das S,Handler JS,Hajdu CH,Coffre M,Koralov SB,Bar-Sagi D
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Medial HOXA genes demarcate haematopoietic stem cell fate during human development.
Nature cell biology
Dou DR,Calvanese V,Sierra MI,Nguyen AT,Minasian A,Saarikoski P,Sasidharan R,Ramirez CM,Zack JA,Crooks GM,Galic Z,Mikkola HK
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal.
The Journal of clinical investigation
Haemmerle M,Bottsford-Miller J,Pradeep S,Taylor ML,Choi HJ,Hansen JM,Dalton HJ,Stone RL,Cho MS,Nick AM,Nagaraja AS,Gutschner T,Gharpure KM,Mangala LS,Rupaimoole R,Han HD,Zand B,Armaiz-Pena GN,Wu SY,Pecot CV,Burns AR,Lopez-Berestein G,Afshar-Kharghan V,Sood AK
25-0193 was used in Flow cytometry/Cell sorting to identify focal adhesion kinase, FAK, as a target for ovarian cancer management in situations in which antiangiogenic agents are withdrawn.
Mon May 02 00:00:00 EDT 2016
Development of Th17-Associated Interstitial Kidney Inflammation in Lupus-Prone Mice Lacking the Gene Encoding STAT-1.
Arthritis & rheumatology (Hoboken, N.J.)
Yiu G,Rasmussen TK,Ajami B,Haddon DJ,Chu AD,Tangsombatvisit S,Haynes WA,Diep V,Steinman L,Faix J,Utz PJ
25-0193 was used in Flow cytometry/Cell sorting to investigate the roles of the type I and type II IFN signaling components in systemic Lupus Erythematosus, showing the development of Th17-associated interstitial kidney inflammation in mice lacking STAT-1.
Sun May 01 00:00:00 EDT 2016
Superenhancer reprogramming drives a B-cell-epithelial transition and high-risk leukemia.
Genes & development
Hu Y,Zhang Z,Kashiwagi M,Yoshida T,Joshi I,Jena N,Somasundaram R,Emmanuel AO,Sigvardsson M,Fitamant J,El-Bardeesy N,Gounari F,Van Etten RA,Georgopoulos K
25-0193 was used in Flow cytometry/Cell sorting to demonstrate the role played by IKAROS in the regulation of precursor B-cell acute lymphoblastic leukaemia development via superenhancers.
Thu Sep 01 00:00:00 EDT 2016
Id2 regulates hyporesponsive invariant natural killer T cells.
Immunology and cell biology
Stradner MH,Cheung KP,Lasorella A,Goldrath AW,D'Cruz LM
25-0193 was used in Flow cytometry/Cell sorting to propose that downregulation of Id2 expression is essential to induction of the anti-inflammatory state in iNKT cells.
Mon Aug 01 00:00:00 EDT 2016
Antigen Targeting to Human HLA Class II Molecules Increases Efficacy of DNA Vaccination.
Journal of immunology (Baltimore, Md. : 1950)
Grodeland G,Fredriksen AB,Løset GÅ,Vikse E,Fugger L,Bogen B
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2016
The impact of chronic intermittent hypoxia on hematopoiesis and the bone marrow microenvironment.
Pflugers Archiv : European journal of physiology
Alvarez-Martins I,Remédio L,Matias I,Diogo LN,Monteiro EC,Dias S
25-0193 was used in Flow cytometry/Cell sorting to investigate how chronic intermittent hypoxia affects hematopoiesis and the bone marrow microenvironment.
Sun May 01 00:00:00 EDT 2016
CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity.
Nature communications
Jacoby E,Nguyen SM,Fountaine TJ,Welp K,Gryder B,Qin H,Yang Y,Chien CD,Seif AE,Lei H,Song YK,Khan J,Lee DW,Mackall CL,Gardner RA,Jensen MC,Shern JF,Fry TJ
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Wed Jul 27 00:00:00 EDT 2016
Novel CXCL13 transgenic mouse: inflammation drives pathogenic effect of CXCL13 in experimental myasthenia gravis.
Oncotarget
Weiss JM,Robinet M,Aricha R,Cufi P,Villeret B,Lantner F,Shachar I,Fuchs S,Souroujon MC,Berrih-Aknin S,Le Panse R
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Tue Feb 16 00:00:00 EST 2016
Protein Kinase D2 Protects against Acute Colitis Induced by Dextran Sulfate Sodium in Mice.
Scientific reports
Xiong J,Zhou MF,Wang YD,Chen LP,Xu WF,Wang YD,Deng F,Liu SD
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Fri Sep 23 00:00:00 EDT 2016
Fat-associated lymphoid clusters control local IgM secretion during pleural infection and lung inflammation.
Nature communications
Jackson-Jones LH,Duncan SM,Magalhaes MS,Campbell SM,Maizels RM,McSorley HJ,Allen JE,Bénézech C
25-0193 was used in Flow cytometry/Cell sorting to reveal a link between inflammation, IL-33 release by FALC stromal cells, ILC2 activation and pleural B-cell activation in FALCs, resulting in local and antigen-specific IgM production.
Thu Sep 01 00:00:00 EDT 2016
Antibodies That Block or Activate Mouse B Cell Activating Factor of the Tumor Necrosis Factor (TNF) Family (BAFF), Respectively, Induce B Cell Depletion or B Cell Hyperplasia.
The Journal of biological chemistry
Kowalczyk-Quintas C,Schuepbach-Mallepell S,Vigolo M,Willen L,Tardivel A,Smulski CR,Zheng TS,Gommerman J,Hess H,Gottenberg JE,Mackay F,Donzé O,Schneider P
25-0193 was used in Flow cytometry/Cell sorting to investigate the ability of different monoclonal antibodies to recognize, inhibit, or activate mouse BAFF.
Fri Sep 16 00:00:00 EDT 2016
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Early virus-host interactions dictate the course of a persistent infection.
PLoS pathogens
Sullivan BM,Teijaro JR,de la Torre JC,Oldstone MB
25-0193 was used in Flow cytometry/Cell sorting to investigate the very early host-virus interactions that determine the establishment of viral persistence.
Thu Jan 01 00:00:00 EST 2015
Role of caveolin-3 in lymphocyte activation.
Life sciences
Tran C,Stary CM,Schilling JM,Bentley B,Patel HH,Roth DM
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Thu Jan 15 00:00:00 EST 2015
B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses.
Journal of immunology (Baltimore, Md. : 1950)
Pone EJ,Lam T,Lou Z,Wang R,Chen Y,Liu D,Edinger AL,Xu Z,Casali P
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions.
Journal of immunology (Baltimore, Md. : 1950)
Thiele M,Kerschbaumer RJ,Tam FW,Völkel D,Douillard P,Schinagl A,Kühnel H,Smith J,McDaid JP,Bhangal G,Yu MC,Pusey CD,Cook HT,Kovarik J,Magelky E,Bhan A,Rieger M,Mudde GC,Ehrlich H,Jilma B,Tilg H,Moschen A,Terhorst C,Scheiflinger F
25-0193 was used in Flow cytometry/Cell sorting to demonstrate that oxMIF represents the disease-related isoform of MIF and is therefore a new diagnostic marker for inflammation.
Tue Sep 01 00:00:00 EDT 2015
IRF-1 promotes liver transplant ischemia/reperfusion injury via hepatocyte IL-15/IL-15Rα production.
Journal of immunology (Baltimore, Md. : 1950)
Yokota S,Yoshida O,Dou L,Spadaro AV,Isse K,Ross MA,Stolz DB,Kimura S,Du Q,Demetris AJ,Thomson AW,Geller DA
25-0193 was used in Flow cytometry/Cell sorting to determine the role of IRF-1 during ischemia/reperfusion injury following allogeneic liver transplant, showing that it promotes injury via hepatocyte IL-15/IL-15Rα production.
Mon Jun 15 00:00:00 EDT 2015
Mouse bone marrow-derived mesenchymal stem cells inhibit leukemia/lymphoma cell proliferation in vitro and in a mouse model of allogeneic bone marrow transplant.
International journal of molecular medicine
Song N,Gao L,Qiu H,Huang C,Cheng H,Zhou H,Lv S,Chen L,Wang J
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
B cells modulate systemic responses to Pneumocystis murina lung infection and protect on-demand hematopoiesis via T cell-independent innate mechanisms when type I interferon signaling is absent.
Infection and immunity
Hoyt TR,Dobrinen E,Kochetkova I,Meissner N
25-0193 was used in Flow cytometry/Cell sorting to show how B cells promote the replenishment of depleted bone marrow cells during systemic responses to Pneumocystis lung infection.
Sun Feb 01 00:00:00 EST 2015
dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.
Nature communications
Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM
25-0193 was used in Flow cytometry/Cell sorting to demonstrate amelioration of experimental autoimmune encephalomyelitis by a blood brain barrier permeable peptide to deliver ctCTLA-4 protein.
Tue Sep 15 00:00:00 EDT 2015
Vesicles from different Trypanosoma cruzi strains trigger differential innate and chronic immune responses.
Journal of extracellular vesicles
Nogueira PM,Ribeiro K,Silveira AC,Campos JH,Martins-Filho OA,Bela SR,Campos MA,Pessoa NL,Colli W,Alves MJ,Soares RP,Torrecilhas AC
25-0193 was used in Flow cytometry/Cell sorting to reveal polymorphisms in the vesicles surface may be determinant in the immunopathologic events throughout infection.
Sat Nov 28 00:00:00 EST 2015
Stoichiometry of Heteromeric BAFF and APRIL Cytokines Dictates Their Receptor Binding and Signaling Properties.
The Journal of biological chemistry
Schuepbach-Mallepell S,Das D,Willen L,Vigolo M,Tardivel A,Lebon L,Kowalczyk-Quintas C,Nys J,Smulski C,Zheng TS,Maskos K,Lammens A,Jiang X,Hess H,Tan SL,Schneider P
25-0193 was used in Flow cytometry/Cell sorting to study how BAFF-APRIL heteromers of different stoichiometries have distinct receptor-binding properties and activities.
Fri Jun 26 00:00:00 EDT 2015
Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes.
Nature medicine
Clatworthy MR,Aronin CE,Mathews RJ,Morgan NY,Smith KG,Germain RN
25-0193 was used in Flow cytometry/Cell sorting to study how immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes.
Mon Dec 01 00:00:00 EST 2014
Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes.
Nature medicine
Clatworthy MR,Aronin CE,Mathews RJ,Morgan NY,Smith KG,Germain RN
25-0193 was used in Flow cytometry/Cell sorting to study how immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes.
Mon Dec 01 00:00:00 EST 2014
Coinfection with Streptococcus pneumoniae modulates the B cell response to influenza virus.
Journal of virology
Wolf AI,Strauman MC,Mozdzanowska K,Whittle JR,Williams KL,Sharpe AH,Weiser JN,Caton AJ,Hensley SE,Erikson J
25-0193 was used in Flow cytometry/Cell sorting to demonstrate how co-infection of S. pneumoniae and influenza virus may affect the generation of protective antiviral antibodies.
Wed Oct 01 00:00:00 EDT 2014
Wild-type bone marrow transplant partially reverses neuroinflammation in progranulin-deficient mice.
Laboratory investigation; a journal of technical methods and pathology
Yang Y,Aloi MS,Cudaback E,Josephsen SR,Rice SJ,Jorstad NL,Keene CD,Montine TJ
25-0193 was used in Flow cytometry/Cell sorting to reveal that BMT can be administered as a stem cell-based approach to prevent or to treat neurodegenerative diseases.
Sat Nov 01 00:00:00 EDT 2014
Eosinophils regulate peripheral B cell numbers in both mice and humans.
Journal of immunology (Baltimore, Md. : 1950)
Wong TW,Doyle AD,Lee JJ,Jelinek DF
25-0193 was used in Flow cytometry/Cell sorting to assess the effect of eosinophils on B cell survival, proliferation, and Ig secretion.
Tue Apr 15 00:00:00 EDT 2014
CD40 ligand preferentially modulates immune response and enhances protection against influenza virus.
Journal of immunology (Baltimore, Md. : 1950)
Hashem AM,Gravel C,Chen Z,Yi Y,Tocchi M,Jaentschke B,Fan X,Li C,Rosu-Myles M,Pereboev A,He R,Wang J,Li X
25-0193 was used in Flow cytometry/Cell sorting to characterise an increased in vivo load of CD40-targeted Ag upon the secretion of the NP-CD40L fusion protein from adenovirus-infected cells.
Tue Jul 15 00:00:00 EDT 2014
Overexpression of Fas and FasL is associated with infectious complications and severity of experimental severe acute pancreatitis by promoting apoptosis of lymphocytes.
Inflammation
Pinhu L,Qin Y,Xiong B,You Y,Li J,Sooranna SR
25-0193 was used in Flow cytometry/Cell sorting to investigate the contribution of Fas/FasL expression to the pathogenic immune response to pancreatitis.
Fri Aug 01 00:00:00 EDT 2014
Efficient B cell responses to Borrelia hermsii infection depend on BAFF and BAFFR but not TACI.
Infection and immunity
Dickinson GS,Sun G,Bram RJ,Alugupalli KR
25-0193 was used in Flow cytometry/Cell sorting to examine the role of BAFFR and TACI in T cell-independent antibody responses to an active Borrelia hermsii infection.
Wed Jan 01 00:00:00 EST 2014
Generation of a novel Cr2 gene allele by homologous recombination that abrogates production of Cr2 but is sufficient for expression of Cr1.
Immunobiology
Donius LR,Orlando CM,Weis JJ,Weis JH
25-0193 was used in Flow cytometry/Cell sorting to study how the Cr2KO mouse provides a new model system for the analysis of Cr1 and Cr2 functions in the immune response of the mouse.
Wed Jan 01 00:00:00 EST 2014
Trypanosoma cruzi trans-sialidase initiates a program independent of the transcription factors RORγt and Ahr that leads to IL-17 production by activated B cells.
Nature immunology
Bermejo DA,Jackson SW,Gorosito-Serran M,Acosta-Rodriguez EV,Amezcua-Vesely MC,Sather BD,Singh AK,Khim S,Mucci J,Liggitt D,Campetella O,Oukka M,Gruppi A,Rawlings DJ
25-0193 was used in Flow cytometry/Cell sorting to study how the generation of IL-17 B cells may be a feature of innate immune responses required for pathogen control or IL-17-mediated autoimmunity.
Wed May 01 00:00:00 EDT 2013
B cells from knock-in mice expressing broadly neutralizing HIV antibody b12 carry an innocuous B cell receptor responsive to HIV vaccine candidates.
Journal of immunology (Baltimore, Md. : 1950)
Ota T,Doyle-Cooper C,Cooper AB,Doores KJ,Aoki-Ota M,Le K,Schief WR,Wyatt RT,Burton DR,Nemazee D
25-0193 was used in Flow cytometry/Cell sorting to demonstrate a new mouse model for testing vaccine candidates for the routine elicitation of broadly neutralising antibodies against HIV.
Sun Sep 15 00:00:00 EDT 2013
Intratumoral delivery of low doses of anti-CD40 mAb combined with monophosphoryl lipid a induces local and systemic antitumor effects in immunocompetent and T cell-deficient mice.
Journal of immunotherapy (Hagerstown, Md. : 1997)
Van De Voort TJ,Felder MA,Yang RK,Sondel PM,Rakhmilevich AL
25-0193 was used in Flow cytometry/Cell sorting to assess the immunomodulatory and antitumour synergy between an agonistic anti-CD40 monoclonal antibody and monophosphoryl lipid A in mice.
Tue Jan 01 00:00:00 EST 2013
Liver accumulation of Plasmodium chabaudi-infected red blood cells and modulation of regulatory T cell and dendritic cell responses.
PloS one
Medeiros MM,da Silva HB,Reis AS,Barboza R,Thompson J,Lima MR,Marinho CR,Tadokoro CE
25-0193 was used in Flow cytometry/Cell sorting to determine that malaria parasite accumulation could be an escape mechanism to avoid sterile immunity sponsored by a tolerogenic environment.
Wed Dec 17 00:00:00 EST 2014
The kinase TBK1 controls IgA class switching by negatively regulating noncanonical NF-κB signaling.
Nature immunology
Jin J,Xiao Y,Chang JH,Yu J,Hu H,Starr R,Brittain GC,Chang M,Cheng X,Sun SC
25-0193 was used in Flow cytometry/Cell sorting to study how immunoglobulin isotype switching is controlled, showing that kinase TBK1 is a pivotal negative regulator of class switching to the immunoglobulin A (IgA) isotype, by attenuating noncanonical signaling via the transcription factor NF-κB.
Thu Nov 01 00:00:00 EDT 2012
Biphenotypic B-lymphoid/myeloid cells expressing low levels of Pax5: potential targets of BAL development.
Blood
Simmons S,Knoll M,Drewell C,Wolf I,Mollenkopf HJ,Bouquet C,Melchers F
25-0193 was used in Flow cytometry/Cell sorting to investigate how variation in Pax5 expression influences hematopoietic development, showing that biphenotypic B-lymphoid/myeloid cells expressing low levels of Pax5 could be targets for BAL.
Thu Nov 01 00:00:00 EDT 2012
Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress.
The Journal of experimental medicine
Austin WR,Armijo AL,Campbell DO,Singh AS,Hsieh T,Nathanson D,Herschman HR,Phelps ME,Witte ON,Czernin J,Radu CG
25-0193 was used in Flow cytometry/Cell sorting to investigate a functional link between nucleotide deficiency, replication stress, and two enzymes of the nucleoside salvage pathway: deoxycytidine kinase and thymidine kinase.
Mon Nov 19 00:00:00 EST 2012
A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells.
Autophagy
Phadwal K,Alegre-Abarrategui J,Watson AS,Pike L,Anbalagan S,Hammond EM,Wade-Martins R,McMichael A,Klenerman P,Simon AK
Published figure using CD19 monoclonal antibody (Product # 25-0193-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2012
Critical role of B cell lymphoma 10 in BAFF-regulated NF-κB activation and survival of anergic B cells.
Journal of immunology (Baltimore, Md. : 1950)
Yu M,Chen Y,He Y,Podd A,Fu G,Wright JA,Kleiman E,Khan WN,Wen R,Wang D
25-0193 was used in Western Blotting to demonstrate the essential role of Bcl10 in ensuring efficacy of BAFF, responsible for regulating NF-κB activation and subsequent survival of anergic B cells.
Sat Dec 01 00:00:00 EST 2012
B7-CD28 costimulatory signals control the survival and proliferation of murine and human γδ T cells via IL-2 production.
Journal of immunology (Baltimore, Md. : 1950)
Ribot JC,Debarros A,Mancio-Silva L,Pamplona A,Silva-Santos B
25-0193 was used in Flow cytometry/Cell sorting to show that CD28 signals are required for IL-2-mediated survival and proliferation of both CD27(+) and CD27(-) γδ T cell subsets.
Wed Aug 01 00:00:00 EDT 2012
Increased levels of prolactin receptor expression correlate with the early onset of lupus symptoms and increased numbers of transitional-1 B cells after prolactin treatment.
BMC immunology
Ledesma-Soto Y,Blanco-Favela F,Fuentes-Pananá EM,Tesoro-Cruz E,Hernández-González R,Arriaga-Pizano L,Legorreta-Haquet MV,Montoya-Diaz E,Chávez-Sánchez L,Castro-Mussot ME,Chávez-Rueda AK
25-0193 was used in Flow cytometry/Cell sorting to determine if different splenic B cell subsets express the prolactin receptor and if the presence of prolactin influences these B cell subsets and correlates with development of lupus.
Fri Mar 09 00:00:00 EST 2012
Transmembrane mutations in Toll-like receptor 9 bypass the requirement for ectodomain proteolysis and induce fatal inflammation.
Immunity
Mouchess ML,Arpaia N,Souza G,Barbalat R,Ewald SE,Lau L,Barton GM
25-0193 was used in Flow cytometry/Cell sorting to elucidate residues within the TLR9 transmembrane region that confer the requirement for ectodomain proteolysis.
Wed Nov 23 00:00:00 EST 2011
RelA and RelB transcription factors in distinct thymocyte populations control lymphotoxin-dependent interleukin-17 production in γδ T cells.
Immunity
Powolny-Budnicka I,Riemann M,Tänzer S,Schmid RM,Hehlgans T,Weih F
25-0193 was used in Flow cytometry/Cell sorting to investigate the contribution of NF-κB to IL-17 production by T cells, showing that RelA and RelB in distinct thymocyte populations control lymphotoxin-dependent IL-17 production.
Fri Mar 25 00:00:00 EDT 2011
A critical role for SOCS3 in innate resistance to Toxoplasma gondii.
Cell host & microbe
Whitmarsh RJ,Gray CM,Gregg B,Christian DA,May MJ,Murray PJ,Hunter CA
25-0193 was used in Flow cytometry/Cell sorting to study the role of SOCS3 in suppressing IL-6 signalling during immune responses to T. gondii infection.
Thu Sep 15 00:00:00 EDT 2011
Retinoic acid induces homing of protective T and B cells to the gut after subcutaneous immunization in mice.
The Journal of clinical investigation
Hammerschmidt SI,Friedrichsen M,Boelter J,Lyszkiewicz M,Kremmer E,Pabst O,Förster R
25-0193 was used in Flow cytometry/Cell sorting to investigate the effectiveness of retinoic acid-assisted subcutaneous immunisation as a novel approach to vaccination against enteropathogens.
Mon Aug 01 00:00:00 EDT 2011
PML-RARA can increase hematopoietic self-renewal without causing a myeloproliferative disease in mice.
The Journal of clinical investigation
Welch JS,Yuan W,Ley TJ
25-0193 was used in Flow cytometry/Cell sorting to study a platform for more accurately dissecting the early events in acute promyelocytic leukemia pathogenesis.
Fri Apr 01 00:00:00 EDT 2011
Liver-expressed Igkappa superantigen induces tolerance of polyclonal B cells by clonal deletion not kappa to lambda receptor editing.
The Journal of experimental medicine
Ota T,Ota M,Duong BH,Gavin AL,Nemazee D
25-0193 was used in Flow cytometry/Cell sorting to postulate that clonal deletion is the major irreversible pathway of tolerance induction among peripheral B cells.
Mon Mar 14 00:00:00 EDT 2011
Dermatan sulfate interacts with dead cells and regulates CD5(+) B-cell fate: implications for a key role in autoimmunity.
The American journal of pathology
Wang JY,Lee J,Yan M,Rho JH,Roehrl MH
25-0193 was used in Flow cytometry/Cell sorting to investigate the mechanisms underlying the positive selection and expansion of CD5(+) B cells, showing that dermatan sulfate interacts with dead cells and regulates CD5(+) B-cell fate.
Sun May 01 00:00:00 EDT 2011
Negative selection by IgM superantigen defines a B cell central tolerance compartment and reveals mutations allowing escape.
Journal of immunology (Baltimore, Md. : 1950)
Duong BH,Ota T,Aoki-Ota M,Cooper AB,Ait-Azzouzene D,Vela JL,Gavin AL,Nemazee D
25-0193 was used in Flow cytometry/Cell sorting to demonstrate the usefulness of reconstituted IgM(b) superantigen hosts in revealing pathways involved in central tolerance.
Thu Dec 01 00:00:00 EST 2011
Genetic variation determines mast cell functions in experimental asthma.
Journal of immunology (Baltimore, Md. : 1950)
Becker M,Reuter S,Friedrich P,Doener F,Michel A,Bopp T,Klein M,Schmitt E,Schild H,Radsak MP,Echtenacher B,Taube C,Stassen M
25-0193 was used in Flow cytometry/Cell sorting to investigate the role of mast cells in allergic asthma.
Wed Jun 15 00:00:00 EDT 2011
Topical imiquimod has therapeutic and immunomodulatory effects against intracranial tumors.
Journal of immunotherapy (Hagerstown, Md. : 1997)
Xiong Z,Ohlfest JR
25-0193 was used in Flow cytometry/Cell sorting to demonstrate that topical application of the TLR7 agonist imiquimod can enhance T-cell responses to intracranial tumors as a single agent in mice.
Fri Apr 01 00:00:00 EDT 2011
Critical roles for c-Myb in lymphoid priming and early B-cell development.
Blood
Greig KT,de Graaf CA,Murphy JM,Carpinelli MR,Pang SH,Frampton J,Kile BT,Hilton DJ,Nutt SL
25-0193 was used in Flow cytometry/Cell sorting to investigate the role c-Myb plays in B lymphopoiesis.
Thu Apr 08 00:00:00 EDT 2010
Expression and role of FLT3 in regulation of the earliest stage of normal granulocyte-monocyte progenitor development.
Blood
Böiers C,Buza-Vidas N,Jensen CT,Pronk CJ,Kharazi S,Wittmann L,Sitnicka E,Hultquist A,Jacobsen SE
25-0193 was used in Flow cytometry/Cell sorting to investigate the role of FLT3 in early granulocyte-monocyte progenitors (GMPs), showing that most GMPs are derived from FLT3-expressing progenitors.
Thu Jun 17 00:00:00 EDT 2010
PD-L1 blockade improves survival in experimental sepsis by inhibiting lymphocyte apoptosis and reversing monocyte dysfunction.
Critical care (London, England)
Zhang Y,Zhou Y,Lou J,Li J,Bo L,Zhu K,Wan X,Deng X,Cai Z
25-0193 was used in Flow cytometry/Cell sorting to investigate the function and mechanism of action of PD-L1 in experimental sepsis in mice.
Thu Jan 26 00:00:00 EST 2012
The Justy mutation identifies Gon4-like as a gene that is essential for B lymphopoiesis.
The Journal of experimental medicine
Lu P,Hankel IL,Knisz J,Marquardt A,Chiang MY,Grosse J,Constien R,Meyer T,Schroeder A,Zeitlmann L,Al-Alem U,Friedman AD,Elliott EI,Meyerholz DK,Waldschmidt TJ,Rothman PB,Colgan JD
25-0193 was used in Flow cytometry/Cell sorting to investigate the role of Gon4-like in B lymphopoiesis.
Mon Jul 05 00:00:00 EDT 2010
Peripheral B cell tolerance and function in transgenic mice expressing an IgD superantigen.
Journal of immunology (Baltimore, Md. : 1950)
Duong BH,Ota T,Aït-Azzouzene D,Aoki-Ota M,Vela JL,Huber C,Walsh K,Gavin AL,Nemazee D
25-0193 was used in Flow cytometry/Cell sorting to generate mice which ubiquitously expressed a membrane-bound IgD-superantigen, to provide a model which should facilitate studies of peripheral B cell tolerance in future.
Thu Apr 15 00:00:00 EDT 2010
Antigen-specific immunity and cross-priming by epithelial ovarian carcinoma-induced CD11b(+)Gr-1(+) cells.
Journal of immunology (Baltimore, Md. : 1950)
Tomihara K,Guo M,Shin T,Sun X,Ludwig SM,Brumlik MJ,Zhang B,Curiel TJ,Shin T
25-0193 was used in Flow cytometry/Cell sorting to investigate CD11b(+)Gr-1(+) cells found in epithelial ovarian cancer-bearing mice, which are induced by ovarian cancer cells and undergo antigen-specific immunity and cross-priming.
Tue Jun 01 00:00:00 EDT 2010
Additive and global functions of HoxA cluster genes in mesoderm derivatives.
Developmental biology
Di-Poï N,Koch U,Radtke F,Duboule D
25-0193 was used in Flow cytometry/Cell sorting to report that mutant mice lacking the entire HoxA cluster in mesodermal lineages display the expected spectrum of postnatal respiratory, cardiac and urogenital defects, previously reported for single gene mutations.
Sat May 15 00:00:00 EDT 2010
