Product References
Cissus quadrangularis (Hadjod) Inhibits RANKL-Induced Osteoclastogenesis and Augments Bone Health in an Estrogen-Deficient Preclinical Model of Osteoporosis Via Modulating the Host Osteoimmune System.
Cells
Azam Z,Sapra L,Baghel K,Sinha N,Gupta RK,Soni V,Saini C,Mishra PK,Srivastava RK
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Wed Jan 04 00:00:00 EST 2023
Deletion of CD36 exhibits limited impact on normal hematopoiesis and the leukemia microenvironment.
Cellular & molecular biology letters
Meng Y,Pospiech M,Ali A,Chandwani R,Vergel M,Onyemaechi S,Yaghmour G,Lu R,Alachkar H
48-0193-82 was used in Flow cytometry/Cell sorting to investigate whether targeting CD36 has any detrimental impact on normal hematopoietic cells.
Wed May 24 00:00:00 EDT 2023
Role of FGF10/FGFR2b Signaling in Homeostasis and Regeneration of Adult Lacrimal Gland and Corneal Epithelium Proliferation.
Investigative ophthalmology & visual science
Finburgh EN,Mauduit O,Noguchi T,Bu JJ,Abbas AA,Hakim DF,Bellusci S,Meech R,Makarenkova HP,Afshari NA
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Tue Jan 03 00:00:00 EST 2023
BEX1 is a critical determinant of viral myocarditis.
PLoS pathogens
Martens CR,Dorn LE,Kenney AD,Bansal SS,Yount JS,Accornero F
48-0193-82 was used in Flow Cytometry to suggest a multifaceted role of BEX1 in the cardiac antiviral immune response.
Tue Feb 01 00:00:00 EST 2022
Single-cell transcriptomics reveals distinct cell response between acute and chronic pulmonary infection of Pseudomonas aeruginosa.
MedComm
Hu X,Wu M,Ma T,Zhang Y,Zou C,Wang R,Zhang Y,Ren Y,Li Q,Liu H,Li H,Wang T,Sun X,Yang Y,Tang M,Li X,Li J,Gao X,Li T,Zhou X
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Immunohistochemistry
Thu Dec 01 00:00:00 EST 2022
Valosin-containing protein (VCP/p97) inhibition reduces viral clearance and induces toxicity associated with muscular damage.
Cell death & disease
Del Rio Oliva M,Basler M
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
Maturation and specialization of group 2 innate lymphoid cells through the lung-gut axis.
Nature communications
Zhao M,Shao F,Yu D,Zhang J,Liu Z,Ma J,Xia P,Wang S
48-0193-82 was used in Flow cytometry/Cell sorting to show that ILC2s undergo translocation via the lung-gut axis upon IL-33 treatment.
Fri Dec 09 00:00:00 EST 2022
Sex-distinct microglial activation and myeloid cell infiltration in the spinal cord after painful peripheral injury.
Neurobiology of pain (Cambridge, Mass.)
Huck NA,Donovan LJ,Shen H,Jordan CE,Muwanga GPB,Bridges CM,Forman TE,Cordonnier SA,Haight ES,Dale-Huang F,Takemura Y,Tawfik VL
48-0193-82 was used in Flow cytometry/Cell sorting to demonstrate that spinal cord TMEM119+ microglia are the cellular source of cytokines IL6 and IL1β after peripheral injury.
Thu May 25 00:00:00 EDT 2023
High-yield enrichment of mouse small intestine intraepithelial lymphocytes by immunomagnetic depletion of EpCAM+ cells.
STAR protocols
Prakhar P,Gonzalez V,Park JH
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Fri Mar 18 00:00:00 EDT 2022
Circadian Dependence of the Acute Immune Response to Myocardial Infarction.
Frontiers in pharmacology
Kilgallen AB,van den Akker F,Feyen DAM,Crnko S,Snijders Blok CJB,Gremmels H,du Pré BC,Reijers R,Doevendans PA,de Jager SCA,Sluijter JPG,Sampaio-Pinto V,van Laake LW
48-0193-82 was used in Flow cytometry/Cell sorting to characterize the immune response and myocardial damage 3 hours after a MI occurs over a full twenty-four-hour period to investigate the role of the circadian rhythms in this response.
Sat Sep 16 00:00:00 EDT 2023
A p38α-BLIMP1 signalling pathway is essential for plasma cell differentiation.
Nature communications
Wu J,Yang K,Cai S,Zhang X,Hu L,Lin F,Wu SQ,Xiao C,Liu WH,Han J
48-0193-82 was used in Flow cytometry/Cell sorting to show that plasma cell differentiation and antibody responses are severely impaired in mice with B-cell-specific deletion of p38α, while B-cell development and the germinal centre B-cell response are spared.
Mon Nov 28 00:00:00 EST 2022
A role of PIEZO1 in iron metabolism in mice and humans.
Cell
Ma S,Dubin AE,Zhang Y,Mousavi SAR,Wang Y,Coombs AM,Loud M,Andolfo I,Patapoutian A
48-0193-82 was used in Flow Cytometry to link macrophage mechanotransduction to iron metabolism and identifies a genetic risk factor for increased iron levels in African Americans.
Thu Feb 18 00:00:00 EST 2021
The ubiquitin ligase Peli1 inhibits ICOS and thereby Tfh-mediated immunity.
Cellular & molecular immunology
Huang X,Hao S,Liu J,Huang Y,Liu M,Xiao C,Wang Y,Pei S,Yu T,Xu J,Wang H,Dai D,Su X,Xiao Y
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Functional human IgA targets a conserved site on malaria sporozoites.
Science translational medicine
Tan J,Cho H,Pholcharee T,Pereira LS,Doumbo S,Doumtabe D,Flynn BJ,Schön A,Kanatani S,Aylor SO,Oyen D,Vistein R,Wang L,Dillon M,Skinner J,Peterson M,Li S,Idris AH,Molina-Cruz A,Zhao M,Olano LR,Lee PJ,Roth A,Sinnis P,Barillas-Mury C,Kayentao K,Ongoiba A,Francica JR,Traore B,Wilson IA,Seder RA,Crompton PD
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Wed Jun 23 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
48-0193-82 was used in Flow Cytometry to show a persistent accumulation of T cells in mice and human autopsy samples for more than 1 mo after stroke.
Mon Aug 02 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
48-0193-82 was used in Flow Cytometry to show a persistent accumulation of T cells in mice and human autopsy samples for more than 1 mo after stroke.
Mon Aug 02 00:00:00 EDT 2021
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
The Journal of experimental medicine
Ho TT,Dellorusso PV,Verovskaya EV,Bakker ST,Flach J,Smith LK,Ventura PB,Lansinger OM,Hérault A,Zhang SY,Kang YA,Mitchell CA,Villeda SA,Passegué E
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Efficacy and safety of anti-CD45-saporin as conditioning agent for RAG deficiency.
The Journal of allergy and clinical immunology
Castiello MC,Bosticardo M,Sacchetti N,Calzoni E,Fontana E,Yamazaki Y,Draghici E,Corsino C,Bortolomai I,Sereni L,Yu HH,Uva P,Palchaudhuri R,Scadden DT,Villa A,Notarangelo LD
48-0193 was used in Flow cytometry/Cell sorting to improve multilineage engraftment and test nongenotoxic conditioning with anti-CD45 mAbs conjugated with saporin CD45 (CD45-SAP).
Fri Jan 01 00:00:00 EST 2021
The gammaherpesvirus 68 viral cyclin facilitates expression of LANA.
PLoS pathogens
Niemeyer BF,Sanford B,Gibson JE,Berger JN,Oko LM,Medina E,Clambey ET,van Dyk LF
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2021
Temporal Contribution of Myeloid-Lineage TLR4 to the Transition to Chronic Pain: A Focus on Sex Differences.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Huck NA,Siliezar-Doyle J,Haight ES,Ishida R,Forman TE,Wu S,Shen H,Takemura Y,Clark JD,Tawfik VL
48-0193-82 was used in Flow Cytometry to define a more nuanced contribution of this receptor to the acute-to-chronic pain transition in a mouse model of complex regional pain syndrome.
Wed May 12 00:00:00 EDT 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
Regulatory B Cells (Bregs) Inhibit Osteoclastogenesis and Play a Potential Role in Ameliorating Ovariectomy-Induced Bone Loss.
Frontiers in immunology
Sapra L,Bhardwaj A,Mishra PK,Garg B,Verma B,Mishra GC,Srivastava RK
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Thu Nov 04 00:00:00 EDT 2021
Comprehensive mutagenesis identifies the peptide repertoire of a p53 T-cell receptor mimic antibody that displays no toxicity in mice transgenic for human HLA-A*0201.
PloS one
Trenevska I,Anderson AP,Bentley C,Hassanali T,Wiblin S,Maguire S,Pezzella F,Banham AH,Li D
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Wed Sep 29 00:00:00 EDT 2021
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist.
eLife
Glassman CR,Su L,Majri-Morrison SS,Winkelmann H,Mo F,Li P,Pérez-Cruz M,Ho PP,Koliesnik I,Nagy N,Hnizdilova T,Picton LK,Kovar M,Bollyky P,Steinman L,Meyer E,Piehler J,Leonard WJ,Garcia KC
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Tue May 18 00:00:00 EDT 2021
Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition.
Cell
Pasciuto E,Burton OT,Roca CP,Lagou V,Rajan WD,Theys T,Mancuso R,Tito RY,Kouser L,Callaerts-Vegh Z,de la Fuente AG,Prezzemolo T,Mascali LG,Brajic A,Whyte CE,Yshii L,Martinez-Muriana A,Naughton M,Young A,Moudra A,Lemaitre P,Poovathingal S,Raes J,De Strooper B,Fitzgerald DC,Dooley J,Liston A
48-0193 was used in Flow cytometry/Cell sorting to investigate the function of brain-resident CD4 T cells.
Thu Aug 06 00:00:00 EDT 2020
IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression.
Cell
Sadik A,Somarribas Patterson LF,Öztürk S,Mohapatra SR,Panitz V,Secker PF,Pfänder P,Loth S,Salem H,Prentzell MT,Berdel B,Iskar M,Faessler E,Reuter F,Kirst I,Kalter V,Foerster KI,Jäger E,Guevara CR,Sobeh M,Hielscher T,Poschet G,Reinhardt A,Hassel JC,Zapatka M,Hahn U,von Deimling A,Hopf C,Schlichting R,Escher BI,Burhenne J,Haefeli WE,Ishaque N,Böhme A,Schäuble S,Thedieck K,Trump S,Seiffert M,Opitz CA
48-0193 was used in Flow cytometry/Cell sorting to show that IL4I1 blockade opens new avenues for cancer therapy.
Thu Sep 03 00:00:00 EDT 2020
Differential Expression of the Transcription Factor GATA3 Specifies Lineage and Functions of Innate Lymphoid Cells.
Immunity
Zhong C,Zheng M,Cui K,Martins AJ,Hu G,Li D,Tessarollo L,Kozlov S,Keller JR,Tsang JS,Zhao K,Zhu J
48-0193 was used in Flow cytometry/Cell sorting to examine transcription factor(s) determining the fate of LTi progenitors versus non-LTi ILC progenitors.
Tue Jan 14 00:00:00 EST 2020
Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade.
Immunity
Bonavita E,Bromley CP,Jonsson G,Pelly VS,Sahoo S,Walwyn-Brown K,Mensurado S,Moeini A,Flanagan E,Bell CR,Chiang SC,Chikkanna-Gowda CP,Rogers N,Silva-Santos B,Jaillon S,Mantovani A,Reis e Sousa C,Guerra N,Davis DM,Zelenay S
48-0193-82 was used in Flow Cytometry to search for inflammatory regulators of cancer inhibition using patient datasets across human cancers.
Tue Dec 15 00:00:00 EST 2020
During Aspergillus Infection, Monocyte-Derived DCs, Neutrophils, and Plasmacytoid DCs Enhance Innate Immune Defense through CXCR3-Dependent Crosstalk.
Cell host & microbe
Guo Y,Kasahara S,Jhingran A,Tosini NL,Zhai B,Aufiero MA,Mills KAM,Gjonbalaj M,Espinosa V,Rivera A,Luster AD,Hohl TM
48-0193 was used in Flow cytometry/Cell sorting to conclude that pDCs act as positive feedback amplifiers of neutrophil effector activity against inhaled mold conidia.
Wed Jul 08 00:00:00 EDT 2020
Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells.
The Journal of clinical investigation
Khiew SH,Jain D,Chen J,Yang J,Yin D,Young JS,Dent A,Sciammas R,Alegre ML,Chong AS
48-0193 was used in Flow cytometry/Cell sorting to showed that alloreactive B cells were not deleted but rapidly lost their ability to differentiate into germinal center B cells and secrete donor-specific antibodies., by using a murine model of heart tolerance.
Wed Jul 01 00:00:00 EDT 2020
Excessive Costimulation Leads to Dysfunction of Adoptively Transferred T Cells.
Cancer immunology research
Wijewarnasuriya D,Bebernitz C,Lopez AV,Rafiq S,Brentjens RJ
48-0193 was used in Flow cytometry/Cell sorting to show excessive CD28 and 4-1BB co-stimulation can drive chimeric antigen receptor T-cell dysfunction.
Mon Jun 01 00:00:00 EDT 2020
Excessive Costimulation Leads to Dysfunction of Adoptively Transferred T Cells.
Cancer immunology research
Wijewarnasuriya D,Bebernitz C,Lopez AV,Rafiq S,Brentjens RJ
48-0193 was used in Flow cytometry/Cell sorting to show excessive CD28 and 4-1BB co-stimulation can drive chimeric antigen receptor T-cell dysfunction.
Mon Jun 01 00:00:00 EDT 2020
Differentiation Potential of Early- and Late-Passage Adipose-Derived Mesenchymal Stem Cells Cultured under Hypoxia and Normoxia.
Stem cells international
Zhao AG,Shah K,Freitag J,Cromer B,Sumer H
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Tue Oct 06 00:00:00 EDT 2020
Zdhhc2 Is Essential for Plasmacytoid Dendritic Cells Mediated Inflammatory Response in Psoriasis.
Frontiers in immunology
Zhou B,Yang W,Li W,He L,Lu L,Zhang L,Liu Z,Wang Y,Chao T,Huang R,Gu Y,Jia T,Liu Q,Tian S,Pierre P,Maeda T,Liang Y,Kong E
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Wed Jun 23 00:00:00 EDT 2021
CNS Immune Profiling in a Dengue Virus-Infected Immunocompetent Outbred ICR Mice Strain.
Frontiers in cellular and infection microbiology
Shen TJ,Chen CL,Jhan MK,Tseng PC,Lin CF
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Thu Jun 17 00:00:00 EDT 2021
C5aR1 Activation Drives Early IFN-γ Production to Control Experimental Toxoplasma gondii Infection.
Frontiers in immunology
Briukhovetska D,Ohm B,Mey FT,Aliberti J,Kleingarn M,Huber-Lang M,Karsten CM,Köhl J
48-0193 was used in Flow cytometry/Cell sorting to suggest a model in which the C5a/C5aR1 axis promotes IFN-γ production from NK cells as a mechanism to control acute Toxoplasma gondii infection.
Mon Apr 05 00:00:00 EDT 2021
Memory CD73+IgM+ B cells protect against Plasmodium yoelii infection and express Granzyme B.
PloS one
Parra M,Weitner M,Yang A,Akue A,Liu X,Schmidt T,Allman WR,Akkoyunlu M,Derrick SC
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Tue Oct 27 00:00:00 EDT 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Fri Jun 19 00:00:00 EDT 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Fri Jun 19 00:00:00 EDT 2020
Small Molecule Enhancers of Endosome-to-Cytosol Import Augment Anti-tumor Immunity.
Cell reports
Kozik P,Gros M,Itzhak DN,Joannas L,Heurtebise-Chrétien S,Krawczyk PA,Rodríguez-Silvestre P,Alloatti A,Magalhaes JG,Del Nery E,Borner GHH,Amigorena S
48-0193 was used in Flow cytometry/Cell sorting to identify 37 enhancers of antigen import from endolysosomes into the cytosol from screening 700 US Food and Drug Administration (FDA)-approved drugs and reveal their mechanism of action.
Tue Jul 14 00:00:00 EDT 2020
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Mon Jun 29 00:00:00 EDT 2020
Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors.
Cell
Ponzetta A,Carriero R,Carnevale S,Barbagallo M,Molgora M,Perucchini C,Magrini E,Gianni F,Kunderfranco P,Polentarutti N,Pasqualini F,Di Marco S,Supino D,Peano C,Cananzi F,Colombo P,Pilotti S,Alomar SY,Bonavita E,Galdiero MR,Garlanda C,Mantovani A,Jaillon S
48-0193-82 was used in Flow Cytometry to conclude that neutrophils driving UTCαβ polarization and type 1 immunity are essential for resistance against murine sarcomas and selected human tumors.
Thu Jul 11 00:00:00 EDT 2019
Intestinal Permeability and IgA Provoke Immune Vasculitis Linked to Cardiovascular Inflammation.
Immunity
Noval Rivas M,Wakita D,Franklin MK,Carvalho TT,Abolhesn A,Gomez AC,Fishbein MC,Chen S,Lehman TJ,Sato K,Shibuya A,Fasano A,Kiyono H,Abe M,Tatsumoto N,Yamashita M,Crother TR,Shimada K,Arditi M
48-0193-82 was used in Flow Cytometry to investigate intestinal barrier function in vasculitis and observe evidence of intestinal permeability and elevated circulating secretory immunoglobulin A (sIgA) in patients with Kawaski disease, as well as elevated sIgA and IgA deposition in vascular tissues in a mouse model of vasculitis.
Tue Sep 17 00:00:00 EDT 2019
Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting.
Cancer cell
Srivastava S,Salter AI,Liggitt D,Yechan-Gunja S,Sarvothama M,Cooper K,Smythe KS,Dudakov JA,Pierce RH,Rader C,Riddell SR
48-0193 was used in Flow cytometry/Cell sorting to demonstrate the use of “AND” logic gates as a strategy to increase the portfolio of cell surface molecules on solid tumors that can be targeted safely with CAR-T cells.
Mon Mar 18 00:00:00 EDT 2019
Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis.
Cell metabolism
Camell CD,Günther P,Lee A,Goldberg EL,Spadaro O,Youm YH,Bartke A,Hubbard GB,Ikeno Y,Ruddle NH,Schultze J,Dixit VD
48-0193 was used in Flow cytometry/Cell sorting to study the role of ageing within alterations of adipose tissue.
Tue Dec 03 00:00:00 EST 2019
Mechanisms of action of ruxolitinib in murine models of hemophagocytic lymphohistiocytosis.
Blood
Albeituni S,Verbist KC,Tedrick PE,Tillman H,Picarsic J,Bassett R,Nichols KE
48-0193-82 was used in Flow Cytometry to show that ruxolitinib operates through IFN-γ-dependent and -independent mechanisms to dampen HLH by targeting the deleterious effects of T cells and neutrophils, with the latter representing an unappreciated and understudied cell type that contributes to HLH pathogenesis.
Thu Jul 11 00:00:00 EDT 2019
NLRX1 inhibits the early stages of CNS inflammation and prevents the onset of spontaneous autoimmunity.
PLoS biology
Gharagozloo M,Mahmoud S,Simard C,Yamamoto K,Bobbala D,Ilangumaran S,Smith MD,Lamontagne A,Jarjoura S,Denault JB,Blais V,Gendron L,Vilariño-Güell C,Sadovnick AD,Ting JP,Calabresi PA,Amrani A,Gris D
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Sun Sep 01 00:00:00 EDT 2019
CD1d highly expressed on DCs reduces lung tumor burden by enhancing antitumor immunity.
Oncology reports
Li Y,Zhao C,Liu J,Lu Z,Lu M,Gu J,Liu R
48-0193 was used in Flow cytometry/Cell sorting to investigate whether CD1d expression on dendritic cells is capable of enhancing anti-tumour immunity, particularly T-cell related immunity.
Wed May 01 00:00:00 EDT 2019
Peritoneal Cells Mediate Immune Responses and Cross-Protection Against Influenza A Virus.
Frontiers in immunology
Gautam A,Park BK,Kim TH,Akauliya M,Kim D,Maharjan S,Park J,Kim J,Lee H,Park MS,Lee Y,Kwon HJ
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Mon Aug 17 00:00:00 EDT 2020
Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus.
Scientific reports
Goldstein JM,Valido A,Lewandowski JP,Walker RG,Mills MJ,Messemer KA,Besseling P,Lee KH,Wattrus SJ,Cho M,Lee RT,Wagers AJ
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Mon Dec 09 00:00:00 EST 2019
ImmGen report: sexual dimorphism in the immune system transcriptome.
Nature communications
Gal-Oz ST,Maier B,Yoshida H,Seddu K,Elbaz N,Czysz C,Zuk O,Stranger BE,Ner-Gaon H,Shay T
48-0193 was used in Flow cytometry/Cell sorting to show transcriptional sexual dimorphism in macrophages.
Fri Sep 20 00:00:00 EDT 2019
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis.
Cancer discovery
Dominguez PM,Ghamlouch H,Rosikiewicz W,Kumar P,Béguelin W,Fontán L,Rivas MA,Pawlikowska P,Armand M,Mouly E,Torres-Martin M,Doane AS,Calvo Fernandez MT,Durant M,Della-Valle V,Teater M,Cimmino L,Droin N,Tadros S,Motanagh S,Shih AH,Rubin MA,Tam W,Aifantis I,Levine RL,Elemento O,Inghirami G,Green MR,Figueroa ME,Bernard OA,Aoufouchi S,Li S,Shaknovich R,Melnick AM
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2018
PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy.
Cell stem cell
Hsu JI,Dayaram T,Tovy A,De Braekeleer E,Jeong M,Wang F,Zhang J,Heffernan TP,Gera S,Kovacs JJ,Marszalek JR,Bristow C,Yan Y,Garcia-Manero G,Kantarjian H,Vassiliou G,Futreal PA,Donehower LA,Takahashi K,Goodell MA
48-0193 was used in Flow cytometry/Cell sorting to establish the clinical relevance of PPM1D mutations in clonal haematopoiesis and the importance of studying mutation-treatment interactions.
Thu Nov 01 00:00:00 EDT 2018
Human herpesvirus-encoded kinase induces B cell lymphomas in vivo.
The Journal of clinical investigation
Anders PM,Montgomery ND,Montgomery SA,Bhatt AP,Dittmer DP,Damania B
48-0193 was used in Flow cytometry/Cell sorting to analyse the function of viral protein kinase in vivo.
Fri Jun 01 00:00:00 EDT 2018
11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis.
Journal of autoimmunity
Hardy RS,Fenton C,Croft AP,Naylor AJ,Begum R,Desanti G,Buckley CD,Lavery G,Cooper MS,Raza K
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Wed Aug 01 00:00:00 EDT 2018
Intranasal delivery of adjuvant-free peptide nanofibers elicits resident CD8+ T cell responses.
Journal of controlled release : official journal of the Controlled Release Society
Si Y,Wen Y,Kelly SH,Chong AS,Collier JH
48-0193 was used in Flow cytometry/Cell sorting to investigate the extent to which self-assembled peptide nanofibers bearing an influenza peptide epitope elicit antigen-specific CD8+ T cell responses when delivered intranasally, and compare these responses with those elicited by subcutaneous immunization.
Sat Jul 28 00:00:00 EDT 2018
De Novo Fatty Acid Synthesis During Mycobacterial Infection Is a Prerequisite for the Function of Highly Proliferative T Cells, But Not for Dendritic Cells or Macrophages.
Frontiers in immunology
Stüve P,Minarrieta L,Erdmann H,Arnold-Schrauf C,Swallow M,Guderian M,Krull F,Hölscher A,Ghorbani P,Behrends J,Abraham WR,Hölscher C,Sparwasser TD,Berod L
48-0193-82 was used in Flow Cytometry to reveal that acetyl-CoA carboxylase 1-dependent fatty acid synthesis is a crucial mechanism in T cells, but not dendritic cells or macrophages, to fight against mycobacterial infection.
Wed Apr 10 00:00:00 EDT 2019
Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Wang Y,Xiao M,Tao C,Chen J,Wang Z,Yang J,Chen Z,Zou Z,Liu A,Cai D,Jiang Y,Ding C,Li M,Bai X
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
The Role of Allograft Inflammatory Factor-1 in the Effects of Experimental Diabetes on B Cell Functions in the Heart.
Frontiers in cardiovascular medicine
Sarkar A,Shukla SK,Alqatawni A,Kumar A,Addya S,Tsygankov AY,Rafiq K
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Mon Dec 06 00:00:00 EST 2021
In Vitro Differentiation of Gata2 and Ly6a Reporter Embryonic Stem Cells Corresponds to In Vivo Waves of Hematopoietic Cell Generation.
Stem cell reports
Kauts ML,Rodriguez-Seoane C,Kaimakis P,Mendes SC,Cortés-Lavaud X,Hill U,Dzierzak E
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Tue Jan 09 00:00:00 EST 2018
Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus.
Nature communications
Liu J,Huang X,Hao S,Wang Y,Liu M,Xu J,Zhang X,Yu T,Gan S,Dai D,Luo X,Lu Q,Mao C,Zhang Y,Shen N,Li B,Huang M,Zhu X,Jin J,Cheng X,Sun SC,Xiao Y
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Mon Mar 19 00:00:00 EDT 2018
Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
eLife
Moretti FA,Klapproth S,Ruppert R,Margraf A,Weber J,Pick R,Scheiermann C,Sperandio M,Fässler R,Moser M
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
A protocol for generating induced T cells by reprogramming B cells in vivo.
Cell regeneration (London, England)
Weng Q,Hu F,Zhang M,Dong Y,Lv C,Wang Y,Liu X,Wang J
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
Macrophages orchestrate breast cancer early dissemination and metastasis.
Nature communications
Linde N,Casanova-Acebes M,Sosa MS,Mortha A,Rahman A,Farias E,Harper K,Tardio E,Reyes Torres I,Jones J,Condeelis J,Merad M,Aguirre-Ghiso JA
48-0193 was used in Flow cytometry/Cell sorting to show that, in pre-malignant lesions, CCL2 produced by cancer cells and myeloid cells attracts CD206+/Tie2+macrophages and induces Wnt-1 upregulation that in turn downregulates E-cadherin junctions in the HER2+early cancer cells.
Tue Jan 02 00:00:00 EST 2018
A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment.
eLife
Ng KK,Yui MA,Mehta A,Siu S,Irwin B,Pease S,Hirose S,Elowitz MB,Rothenberg EV,Kueh HY
48-0193 was used in Flow cytometry/Cell sorting to study the activation of Bcl11b, which controls T-cell fate commitment.
Tue Nov 20 00:00:00 EST 2018
MicroRNA-155 Protects Group 2 Innate Lymphoid Cells From Apoptosis to Promote Type-2 Immunity.
Frontiers in immunology
Knolle MD,Chin SB,Rana BMJ,Englezakis A,Nakagawa R,Fallon PG,Git A,McKenzie ANJ
48-0193 was used in Flow cytometry/Cell sorting to identify a subset of micro-RNAs that are regulated upon group-2 innate lymphoid cells (ILC2) activation, and establish a specific role for miR-155 in regulating ILC2 survival following activation.
Mon Sep 30 00:00:00 EDT 2019
Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha.
Nature communications
Govindarajan S,Gaublomme D,Van der Cruyssen R,Verheugen E,Van Gassen S,Saeys Y,Tavernier S,Iwawaki T,Bloch Y,Savvides SN,Lambrecht BN,Janssens S,Elewaut D,Drennan MB
48-0193 was used in Flow cytometry/Cell sorting to examine the role of the IRE1α-dependent signalling cascade in coupling constitutive cytokine mRNA expression to the rapid induction of cytokine secretion and effector functions in activated iNKT cells.
Mon Dec 17 00:00:00 EST 2018
Characterization of the Inflammatory Response in Dystrophic Muscle Using Flow Cytometry.
Methods in molecular biology (Clifton, N.J.)
Kastenschmidt JM,Avetyan I,Villalta SA
48-0193 was used in Flow cytometry/Cell sorting to highlight methods for the isolation and study of immune cell populations from muscles of mouse models of DMD.
Tue Jun 05 00:00:00 EDT 2018
Renal Sodium Gradient Orchestrates a Dynamic Antibacterial Defense Zone.
Cell
Berry MR,Mathews RJ,Ferdinand JR,Jing C,Loudon KW,Wlodek E,Dennison TW,Kuper C,Neuhofer W,Clatworthy MR
48-0193-82 was used in Flow Cytometry to reveal a critical accessory role for the homeostatic function of a vital organ in optimizing tissue defense.
Thu Aug 24 00:00:00 EDT 2017
Epithelial-Cell-Derived Phospholipase A2 Group 1B Is an Endogenous Anthelmintic.
Cell host & microbe
Entwistle LJ,Pelly VS,Coomes SM,Kannan Y,Perez-Lloret J,Czieso S,Silva Dos Santos M,MacRae JI,Collinson L,Sesay A,Nikolov N,Metidji A,Helmby H,Hui DY,Wilson MS
48-0193 was used in Flow cytometry/Cell sorting to uncover epithelial-cell-derived Pla2g1b as an essential mediator of helminth killing.
Wed Oct 11 00:00:00 EDT 2017
A therapeutic T cell receptor mimic antibody targets tumor-associated PRAME peptide/HLA-I antigens.
The Journal of clinical investigation
Chang AY,Dao T,Gejman RS,Jarvis CA,Scott A,Dubrovsky L,Mathias MD,Korontsvit T,Zakhaleva V,Curcio M,Hendrickson RC,Liu C,Scheinberg DA
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Fri Jun 30 00:00:00 EDT 2017
Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity.
The Journal of experimental medicine
Thomas DC,Clare S,Sowerby JM,Pardo M,Juss JK,Goulding DA,van der Weyden L,Storisteanu D,Prakash A,Espéli M,Flint S,Lee JC,Hoenderdos K,Kane L,Harcourt K,Mukhopadhyay S,Umrania Y,Antrobus R,Nathan JA,Adams DJ,Bateman A,Choudhary JS,Lyons PA,Condliffe AM,Chilvers ER,Dougan G,Smith KG
48-0193 was used in Flow cytometry/Cell sorting to describe the key role of the previously uncharacterised protein Eros in host defence.
Mon Apr 03 00:00:00 EDT 2017
Critical role for Sec22b-dependent antigen cross-presentation in antitumor immunity.
The Journal of experimental medicine
Alloatti A,Rookhuizen DC,Joannas L,Carpier JM,Iborra S,Magalhaes JG,Yatim N,Kozik P,Sancho D,Albert ML,Amigorena S
48-0193 was used in Flow cytometry/Cell sorting to determine that Sec22b-dependent cross-presentation in dendritic cells is required to initiate CD8 T cell responses to dead cells, and induce effective anti-tumour immune responses during anti-PD-1 treatment.
Mon Aug 07 00:00:00 EDT 2017
ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control.
The Journal of experimental medicine
Schwartz C,Khan AR,Floudas A,Saunders SP,Hams E,Rodewald HR,McKenzie ANJ,Fallon PG
48-0193 was used in Flow cytometry/Cell sorting to study how group 2 innate lymphoid cells regulate adaptive Th2 cell functions.
Mon Sep 04 00:00:00 EDT 2017
DC subset-specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivo.
The Journal of experimental medicine
Lehmann CHK,Baranska A,Heidkamp GF,Heger L,Neubert K,Lühr JJ,Hoffmann A,Reimer KC,Brückner C,Beck S,Seeling M,Kießling M,Soulat D,Krug AB,Ravetch JV,Leusen JHW,Nimmerjahn F,Dudziak D
48-0193 was used in Flow cytometry/Cell sorting to suggest that targeting antigens to FcγRs on DCs may be a promising approach to raise immunogenic or tolerogenic T cell responses to antigens of choice.
Mon May 01 00:00:00 EDT 2017
Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells.
Frontiers in immunology
Bai WJ,Li CG,Zhang CC,Xu LH,Zeng QZ,Hu B,Hong Z,He XH,Ouyang DY
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Use of Toll-Like Receptor Agonists to Induce Ectopic Lymphoid Structures in Myasthenia Gravis Mouse Models.
Frontiers in immunology
Robinet M,Villeret B,Maillard S,Cron MA,Berrih-Aknin S,Le Panse R
48-0193 was used in Flow cytometry/Cell sorting to study the effect of combined activation of toll-like receptor signalling pathways on tertiary lymphoid genesis in the Myasthenia gravis thymus.
Wed Nov 20 00:00:00 EST 2019
ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.
RNA biology
Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M
48-0193 was used in Flow cytometry/Cell sorting to study the regulatory role of ADAR1 in hepatic immune homeostasis.
Thu May 04 00:00:00 EDT 2017
Diminished bone regeneration after debridement of posttraumatic osteomyelitis is accompanied by altered cytokine levels, elevated B cell activity, and increased osteoclast activity.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Wagner JM,Jaurich H,Wallner C,Abraham S,Becerikli M,Dadras M,Harati K,Duhan V,Khairnar V,Lehnhardt M,Behr B
48019382 was used in flow cytometry to infer a RANKL-dependent osteoclastogenesis after debridement of osteomyelitis coinciding with elevated B cells and simultaneously decreased osteogenesis
Wed Nov 01 00:00:00 EDT 2017
Intravenously usable fully serotype 3 oncolytic adenovirus coding for CD40L as an enabler of dendritic cell therapy.
Oncoimmunology
Zafar S,Parviainen S,Siurala M,Hemminki O,Havunen R,Tähtinen S,Bramante S,Vassilev L,Wang H,Lieber A,Hemmi S,de Gruijl T,Kanerva A,Hemminki A
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
Differential regulation of C5a receptor 1 in innate immune cells during the allergic asthma effector phase.
PloS one
Ender F,Wiese AV,Schmudde I,Sun J,Vollbrandt T,König P,Laumonnier Y,Köhl J
48-0193 was used in Flow cytometry/Cell sorting to demonstrate a complex regulation pattern of C5aR1 in the airways, lung tissue and lymph nodes of mice.
Thu Aug 17 00:00:00 EDT 2017
Immunogenicity of Isogenic IgG in Aggregates and Immune Complexes.
PloS one
St Clair JB,Detanico T,Aviszus K,Kirchenbaum GA,Christie M,Carpenter JF,Wysocki LJ
48-0193 was used in Flow cytometry/Cell sorting to analyse CD4 T cell reactions against IgG in various physical states.
Fri Aug 11 00:00:00 EDT 2017
CTLA4-Ig in combination with FTY720 promotes allograft survival in sensitized recipients.
JCI insight
Khiew SH,Yang J,Young JS,Chen J,Wang Q,Yin D,Vu V,Miller ML,Sciammas R,Alegre ML,Chong AS
48-0193 was used in Flow cytometry/Cell sorting to suggest inhibiting memory T cell expansion and trafficking into allografts with CTLA4-Ig and FTY720 promotes allograft survival in allosensitized recipients.
Thu May 04 00:00:00 EDT 2017
IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2.
Nature communications
Jandl C,Liu SM,Cañete PF,Warren J,Hughes WE,Vogelzang A,Webster K,Craig ME,Uzel G,Dent A,Stepensky P,Keller B,Warnatz K,Sprent J,King C
48-0193 was used in Flow cytometry/Cell sorting to identify a mechanism by which IL-21 reinforces humoural immunity by influencing the phenotype of T follicular cells to limit their expansion.
Fri Mar 17 00:00:00 EDT 2017
The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome.
Cell
Gury-BenAri M,Thaiss CA,Serafini N,Winter DR,Giladi A,Lara-Astiaso D,Levy M,Salame TM,Weiner A,David E,Shapiro H,Dori-Bachash M,Pevsner-Fischer M,Lorenzo-Vivas E,Keren-Shaul H,Paul F,Harmelin A,Eberl G,Itzkovitz S,Tanay A,Di Santo JP,Elinav E,Amit I
48-0193 was used in Flow cytometry/Cell sorting to investigate the cellular states and regulatory landscapes of innate lymphoid cells.
Thu Aug 25 00:00:00 EDT 2016
IL35-Producing B Cells Promote the Development of Pancreatic Neoplasia.
Cancer discovery
Pylayeva-Gupta Y,Das S,Handler JS,Hajdu CH,Coffre M,Koralov SB,Bar-Sagi D
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Oligodendrocyte death results in immune-mediated CNS demyelination.
Nature neuroscience
Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B
48-0193 was used in Flow cytometry/Cell sorting to investigate whether oligodendrocyte death could cause an the autoimmune response against myelin.
Fri Jan 01 00:00:00 EST 2016
Medial HOXA genes demarcate haematopoietic stem cell fate during human development.
Nature cell biology
Dou DR,Calvanese V,Sierra MI,Nguyen AT,Minasian A,Saarikoski P,Sasidharan R,Ramirez CM,Zack JA,Crooks GM,Galic Z,Mikkola HK
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.
Science translational medicine
Dendrou CA,Cortes A,Shipman L,Evans HG,Attfield KE,Jostins L,Barber T,Kaur G,Kuttikkatte SB,Leach OA,Desel C,Faergeman SL,Cheeseman J,Neville MJ,Sawcer S,Compston A,Johnson AR,Everett C,Bell JI,Karpe F,Ultsch M,Eigenbrot C,McVean G,Fugger L
48-0193 was used in Flow cytometry/Cell sorting to reveal a protective homozygous effect that defined a signalling optimum between autoimmunity and immunodeficiency and identified TYK2 as a potential drug target for autoimmune disorders.
Wed Nov 02 00:00:00 EDT 2016
Class-switched anti-insulin antibodies originate from unconventional antigen presentation in multiple lymphoid sites.
The Journal of experimental medicine
Wan X,Thomas JW,Unanue ER
48-0193 was used in Flow cytometry/Cell sorting to investigate the interactions of insulin-specific T and B lymphocytes using T cell and B cell receptor transgenic mice.
Mon May 30 00:00:00 EDT 2016
Antigen Targeting to Human HLA Class II Molecules Increases Efficacy of DNA Vaccination.
Journal of immunology (Baltimore, Md. : 1950)
Grodeland G,Fredriksen AB,Løset GÅ,Vikse E,Fugger L,Bogen B
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2016
Protein Translation Activity: A New Measure of Host Immune Cell Activation.
Journal of immunology (Baltimore, Md. : 1950)
Seedhom MO,Hickman HD,Wei J,David A,Yewdell JW
48-0193 was used in Flow cytometry/Cell sorting to describe the in vivo ribopuromycylation method.
Mon Aug 15 00:00:00 EDT 2016
Helios Controls a Limited Subset of Regulatory T Cell Functions.
Journal of immunology (Baltimore, Md. : 1950)
Sebastian M,Lopez-Ocasio M,Metidji A,Rieder SA,Shevach EM,Thornton AM
48-0193 was used in Flow cytometry/Cell sorting to determine the beneficial effects of the transcription factor, Helios, for Treg maintenance, differentiation, and survival.
Fri Jan 01 00:00:00 EST 2016
CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity.
Nature communications
Jacoby E,Nguyen SM,Fountaine TJ,Welp K,Gryder B,Qin H,Yang Y,Chien CD,Seif AE,Lei H,Song YK,Khan J,Lee DW,Mackall CL,Gardner RA,Jensen MC,Shern JF,Fry TJ
48-0193 was used in Flow cytometry/Cell sorting to study how CD19 CAR immune pressure induces a B-precursor acute lymphoblastic leukaemia lineage switch.
Wed Jul 27 00:00:00 EDT 2016
Novel CXCL13 transgenic mouse: inflammation drives pathogenic effect of CXCL13 in experimental myasthenia gravis.
Oncotarget
Weiss JM,Robinet M,Aricha R,Cufi P,Villeret B,Lantner F,Shachar I,Fuchs S,Souroujon MC,Berrih-Aknin S,Le Panse R
48-0193 was used in Flow cytometry/Cell sorting to investigate whether abnormal CXCL13 expression by the thymic epithelium triggers B-cell recruitment in myasthenia gravis, showing that the pathogenic effect of CXCL13 is driven by inflammation.
Tue Feb 16 00:00:00 EST 2016
Protein Kinase D2 Protects against Acute Colitis Induced by Dextran Sulfate Sodium in Mice.
Scientific reports
Xiong J,Zhou MF,Wang YD,Chen LP,Xu WF,Wang YD,Deng F,Liu SD
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Fri Sep 23 00:00:00 EDT 2016
Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development.
Cell reports
Barrett NA,Malouf C,Kapeni C,Bacon WA,Giotopoulos G,Jacobsen SEW,Huntly BJ,Ottersbach K
48-0193 was used in Flow cytometry/Cell sorting to elucidate the contribution of MII-AF4 in B cell acute lymphoblastic leukaemia early development in the mouse embryo.
Tue Jul 26 00:00:00 EDT 2016
Evaluation of Cross-presentation in Bone Marrow-derived Dendritic Cells in vitro and Splenic Dendritic Cells ex vivo Using Antigen-coated Beads.
Bio-protocol
Alloatti A,Kotsias F,Hoffmann E,Amigorena S
48-0193 was used in Flow cytometry/Cell sorting to develop a protocol for evaluating antigen cross-presentation by dendritic cells, both in vivo and ex vivo.
Sun Nov 20 00:00:00 EST 2016
Efficient generation of monoclonal antibodies against peptide in the context of MHCII using magnetic enrichment.
Nature communications
Spanier JA,Frederick DR,Taylor JJ,Heffernan JR,Kotov DI,Martinov T,Osum KC,Ruggiero JL,Rust BJ,Landry SJ,Jenkins MK,McLachlan JB,Fife BT
48-0193 was used in Flow cytometry/Cell sorting to develop a novel approach for the generation and screening of peptide:MHCII reactive mAbs that exploits the use of recombinant peptide:MHC monomers as immunogens.
Mon Jun 13 00:00:00 EDT 2016
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
HDL-bound sphingosine 1-phosphate acts as a biased agonist for the endothelial cell receptor S1P1 to limit vascular inflammation.
Science signaling
Galvani S,Sanson M,Blaho VA,Swendeman SL,Obinata H,Conger H,Dahlbäck B,Kono M,Proia RL,Smith JD,Hla T
48-0193 was used in Flow cytometry/Cell sorting to investigate the role of endothelial cell sphingosine 1-phosphate receptor 1 in adult mice.
Tue Aug 11 00:00:00 EDT 2015
Early virus-host interactions dictate the course of a persistent infection.
PLoS pathogens
Sullivan BM,Teijaro JR,de la Torre JC,Oldstone MB
48-0193 was used in Flow cytometry/Cell sorting to investigate the very early host-virus interactions that determine the establishment of viral persistence.
Thu Jan 01 00:00:00 EST 2015
Role of caveolin-3 in lymphocyte activation.
Life sciences
Tran C,Stary CM,Schilling JM,Bentley B,Patel HH,Roth DM
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Thu Jan 15 00:00:00 EST 2015
B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses.
Journal of immunology (Baltimore, Md. : 1950)
Pone EJ,Lam T,Lou Z,Wang R,Chen Y,Liu D,Edinger AL,Xu Z,Casali P
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Monitoring and cell-specific deletion of C5aR1 using a novel floxed GFP-C5aR1 reporter knock-in mouse.
Journal of immunology (Baltimore, Md. : 1950)
Karsten CM,Laumonnier Y,Eurich B,Ender F,Bröker K,Roy S,Czabanska A,Vollbrandt T,Figge J,Köhl J
48-0193 was used in Flow cytometry/Cell sorting to study cell-specific deletion of C5aR1 using a GFP-reporter knock-in mouse model.
Sun Feb 15 00:00:00 EST 2015
Mouse bone marrow-derived mesenchymal stem cells inhibit leukemia/lymphoma cell proliferation in vitro and in a mouse model of allogeneic bone marrow transplant.
International journal of molecular medicine
Song N,Gao L,Qiu H,Huang C,Cheng H,Zhou H,Lv S,Chen L,Wang J
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.
Nature communications
Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Tue Sep 15 00:00:00 EDT 2015
Group 2 innate lymphoid cells facilitate sensitization to local, but not systemic, TH2-inducing allergen exposures.
The Journal of allergy and clinical immunology
Gold MJ,Antignano F,Halim TY,Hirota JA,Blanchet MR,Zaph C,Takei F,McNagny KM
48-0193 was used in Flow cytometry/Cell sorting to reveal a critical role for ILC2s in the development of adaptive type 2 responses to local antigen exposure.
Tue Apr 01 00:00:00 EDT 2014
Siglec-G deficiency leads to more severe collagen-induced arthritis and earlier onset of lupus-like symptoms in MRL/lpr mice.
Journal of immunology (Baltimore, Md. : 1950)
Bökers S,Urbat A,Daniel C,Amann K,Smith KG,Espéli M,Nitschke L
48-0193 was used in Flow cytometry/Cell sorting to study how loss of the inhibitory receptor Siglec-G led to a moderate exacerbation of disease severity and early onset in both collagen-induced arthritis and spontaneous lupus nephritis.
Tue Apr 01 00:00:00 EDT 2014
Central role of conventional dendritic cells in regulation of bone marrow release and survival of neutrophils.
Journal of immunology (Baltimore, Md. : 1950)
Jiao J,Dragomir AC,Kocabayoglu P,Rahman AH,Chow A,Hashimoto D,Leboeuf M,Kraus T,Moran T,Carrasco-Avino G,Friedman SL,Merad M,Aloman C
48-0193 was used in Flow cytometry/Cell sorting to investigate the role of dendritic cells in neutrophil homeostasis, showing a central role in regulation of bone marrow release and survival of neutrophils.
Tue Apr 01 00:00:00 EDT 2014
Use of transgenic parasites and host reporters to dissect events that promote interleukin-12 production during toxoplasmosis.
Infection and immunity
Christian DA,Koshy AA,Reuter MA,Betts MR,Boothroyd JC,Hunter CA
48-0193 was used in Flow cytometry/Cell sorting to study the cell types which secrete IL-12p40 during Toxoplasma gondii infection.
Wed Oct 01 00:00:00 EDT 2014
DA virus mutant H101 has altered CNS pathogenesis and causes immunosuppression.
Journal of neuroimmunology
Cusick MF,Libbey JE,Doty DJ,Fujinami RS
48-0193 was used in Flow cytometry/Cell sorting to investigate how a few changes in the genome of a non-lethal virus can lead to altered and potentially lethal disease.
Mon Dec 15 00:00:00 EST 2014
Medullary thymic epithelial cell depletion leads to autoimmune hepatitis.
The Journal of clinical investigation
Bonito AJ,Aloman C,Fiel MI,Danzl NM,Cha S,Weinstein EG,Jeong S,Choi Y,Walsh MC,Alexandropoulos K
48-0193 was used in Flow cytometry/Cell sorting to investigate the role of TRAF6 and medullary thymic epithelial cells (mETCs) in autoimmunity, showing that mETC depletion leads to autoimmune hepatitis.
Thu Aug 01 00:00:00 EDT 2013
Nanoparticle clearance is governed by Th1/Th2 immunity and strain background.
The Journal of clinical investigation
Jones SW,Roberts RA,Robbins GR,Perry JL,Kai MP,Chen K,Bo T,Napier ME,Ting JP,Desimone JM,Bear JE
48-0193 was used in Flow cytometry/Cell sorting to investigate the mechanisms involved in the clearance of particles from blood.
Mon Jul 01 00:00:00 EDT 2013
Host immunity contributes to the anti-melanoma activity of BRAF inhibitors.
The Journal of clinical investigation
Knight DA,Ngiow SF,Li M,Parmenter T,Mok S,Cass A,Haynes NM,Kinross K,Yagita H,Koya RC,Graeber TG,Ribas A,McArthur GA,Smyth MJ
48-0193 was used in Flow cytometry/Cell sorting to investigate the contribution of host immunity to the anti-melanoma activity of BRAF inhibitors.
Fri Mar 01 00:00:00 EST 2013
Peripheral elevation of TNF-α leads to early synaptic abnormalities in the mouse somatosensory cortex in experimental autoimmune encephalomyelitis.
Proceedings of the National Academy of Sciences of the United States of America
Yang G,Parkhurst CN,Hayes S,Gan WB
48-0193 was used in Flow cytometry/Cell sorting to examine the effect of inflammation and cytokine elevation on synaptic connections in the primary somatosensory cortex in a mouse model of EAE.
Tue Jun 18 00:00:00 EDT 2013
MHC class II expression in human basophils: induction and lack of functional significance.
PloS one
Voskamp AL,Prickett SR,Mackay F,Rolland JM,O'Hehir RE
48-0193 was used in Flow cytometry/Cell sorting to determine the antigen-presenting abilities of basophils and their role in initiating a Th2 phenotype.
Mon Sep 29 00:00:00 EDT 2014
The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology.
Immunity
Hall AO,Beiting DP,Tato C,John B,Oldenhove G,Lombana CG,Pritchard GH,Silver JS,Bouladoux N,Stumhofer JS,Harris TH,Grainger J,Wojno ED,Wagage S,Roos DS,Scott P,Turka LA,Cherry S,Reiner SL,Cua D,Belkaid Y,Elloso MM,Hunter CA
48-0193 was used in an ELISA assay to study the promotion of distinct Treg cell populations by the cytokines IL-27 and IFN-y, and the role they play in limiting infection induced pathology.
Fri Sep 21 00:00:00 EDT 2012
A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells.
Autophagy
Phadwal K,Alegre-Abarrategui J,Watson AS,Pike L,Anbalagan S,Hammond EM,Wade-Martins R,McMichael A,Klenerman P,Simon AK
48-0193 was used in Flow cytometry/Cell sorting to demonstrate a method to measure autophagy levels in certain diseases, whilst determining the contribution of autophagy to the efficacy of drugs.
Sun Apr 01 00:00:00 EDT 2012
Toxoplasma co-opts host cells it does not invade.
PLoS pathogens
Koshy AA,Dietrich HK,Christian DA,Melehani JH,Shastri AJ,Hunter CA,Boothroyd JC
48-0193 was used in Flow cytometry/Cell sorting to show that in vitro Toxoplasma injects rhoptry proteins into uninfected cells, manipulating them in a similar manner to infected cells.
Tue Jan 29 00:00:00 EST 2013
Critical role of B cell lymphoma 10 in BAFF-regulated NF-κB activation and survival of anergic B cells.
Journal of immunology (Baltimore, Md. : 1950)
Yu M,Chen Y,He Y,Podd A,Fu G,Wright JA,Kleiman E,Khan WN,Wen R,Wang D
Published figure using CD19 monoclonal antibody (Product # 48-0193-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2012
A role for granulocyte-macrophage colony-stimulating factor in the regulation of CD8(+) T cell responses to rabies virus.
Virology
Wanjalla CN,Goldstein EF,Wirblich C,Schnell MJ
48-0193 was used in Flow cytometry/Cell sorting to analyse the effect of GM-CSF on a RABV-vaccine vector co-expressing HIV-1 Gag.
Thu May 10 00:00:00 EDT 2012
Granulocytes and vascularization regulate uterine bleeding and tissue remodeling in a mouse menstruation model.
PloS one
Menning A,Walter A,Rudolph M,Gashaw I,Fritzemeier KH,Roese L
48-0193 was used in Flow cytometry/Cell sorting to investigate mechanisms underlying pathogenesis of menstrual disorders, showing that granulocytes and vascularisation regulate uterine bleeding and tissue remodelling.
Thu Jan 10 00:00:00 EST 2013
Blockade of B7-H1 (programmed death ligand 1) enhances humoral immunity by positively regulating the generation of T follicular helper cells.
Journal of immunology (Baltimore, Md. : 1950)
Hams E,McCarron MJ,Amu S,Yagita H,Azuma M,Chen L,Fallon PG
48-0193 was used in Flow cytometry/Cell sorting to demonstrate that the coinhibitory B7-H1/programmed death 1 pathway can limit the expansion of T(FH) cells and constrain Ag-specific Ig responses.
Sun May 15 00:00:00 EDT 2011
