Product References
Stromal niche inflammation mediated by IL-1 signalling is a targetable driver of haematopoietic ageing.
Nature cell biology
Mitchell CA,Verovskaya EV,Calero-Nieto FJ,Olson OC,Swann JW,Wang X,Hérault A,Dellorusso PV,Zhang SY,Svendsen AF,Pietras EM,Bakker ST,Ho TT,Göttgens B,Passegué E
17-0032-82 was used in Flow cytometry/Cell sorting to characterize the inflammatory milieu that drives both niche and haematopoietic remodelling.
Sun Jan 01 00:00:00 EST 2023
IL-10 Promotes CXCL13 Expression in Macrophages Following Foot-and-Mouth Disease Virus Infection.
International journal of molecular sciences
Guo Z,Chen F,Zhao S,Zhang Z,Zhang H,Bai L,Zhang Z,Li Y
17-0032-82 was used in Immunocytochemistry to demonstrate for the first time that macrophages and T cells were the cellular sources of CXCL13 in mice infected with FMDV; CXCL13 was produced in BMDMs via NF-κB and JAK/STAT pathways; and IL-10 promoted CXCL13 expression in BMDMs via the JAK/STAT pathway.
Tue Mar 28 00:00:00 EDT 2023
LncRNA ANRIL-mediated miR-181b-5p/S1PR1 axis is involved in the progression of uremic cardiomyopathy through activating T cells.
Scientific reports
Xu Y,Cao L,Ji S,Shen W
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Thu Oct 27 00:00:00 EDT 2022
Estrogen Protects against Renal Ischemia-Reperfusion Injury by Regulating Th17/Treg Cell Immune Balance.
Disease markers
Zhang Y,Chang Y,Han Z,Ma K,Zeng X,Li L
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Tue Oct 18 00:00:00 EDT 2022
Therapeutic CFTR Correction Normalizes Systemic and Lung-Specific S1P Level Alterations Associated with Heart Failure.
International journal of molecular sciences
Uhl FE,Vanherle L,Matthes F,Meissner A
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Fri Jan 14 00:00:00 EST 2022
Loss of phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (Pip5k1c) in mesenchymal stem cells leads to osteopenia by impairing bone remodeling.
The Journal of biological chemistry
Yan Q,Gao H,Yao Q,Ling K,Xiao G
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2022
Choroid plexus-selective inactivation of adenosine A2A receptors protects against T cell infiltration and experimental autoimmune encephalomyelitis.
Journal of neuroinflammation
Zheng W,Feng Y,Zeng Z,Ye M,Wang M,Liu X,Tang P,Shang H,Sun X,Lin X,Wang M,Li Z,Weng Y,Guo W,Vakal S,Chen JF
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Fri Feb 18 00:00:00 EST 2022
STAT1 Contributes to Microglial/Macrophage Inflammation and Neurological Dysfunction in a Mouse Model of Traumatic Brain Injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Zhao Y,Ma C,Chen C,Li S,Wang Y,Yang T,Stetler RA,Bennett MVL,Dixon CE,Chen J,Shi Y
17-0032-82 was used in Flow cytometry/Cell sorting to show excellent efficacy of a selective STAT1 inhibitor fludarabine against TBI-induced functional deficits and brain injury using a mouse model, presenting STAT1 as a promising therapeutic target for TBI.
Wed Sep 28 00:00:00 EDT 2022
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
The Journal of experimental medicine
Ho TT,Dellorusso PV,Verovskaya EV,Bakker ST,Flach J,Smith LK,Ventura PB,Lansinger OM,Hérault A,Zhang SY,Kang YA,Mitchell CA,Villeda SA,Passegué E
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
The Journal of experimental medicine
Ho TT,Dellorusso PV,Verovskaya EV,Bakker ST,Flach J,Smith LK,Ventura PB,Lansinger OM,Hérault A,Zhang SY,Kang YA,Mitchell CA,Villeda SA,Passegué E
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Intracellular aggregation of peptide-reprogrammed small molecule nanoassemblies enhances cancer chemotherapy and combinatorial immunotherapy.
Acta pharmaceutica Sinica. B
Peng J,Xiao Y,Yang Q,Liu Q,Chen Y,Shi K,Hao Y,Han R,Qian Z
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
In Vivo HSC Gene Therapy Using a Bi-modular HDAd5/35++ Vector Cures Sickle Cell Disease in a Mouse Model.
Molecular therapy : the journal of the American Society of Gene Therapy
Li C,Wang H,Georgakopoulou A,Gil S,Yannaki E,Lieber A
17-0032-82 was used in Flow Cytometry to report that, after in vivo hematopoietic stem cell/progenitor (HSPC) transduction with HDAd5/35++ vectors, SB100x transposase-mediated γ-globin gene addition achieved 10%-15% γ-globin of adult mouse globin, resulting in significant but incomplete phenotypic correction in a thalassemia intermedia mouse model.
Wed Feb 03 00:00:00 EST 2021
Early inflammation precedes cardiac fibrosis and heart failure in desmoglein 2 murine model of arrhythmogenic cardiomyopathy.
Cell and tissue research
Ng KE,Delaney PJ,Thenet D,Murtough S,Webb CM,Zaman N,Tsisanova E,Mastroianni G,Walker SLM,Westaby JD,Pennington DJ,Pink R,Kelsell DP,Tinker A
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2021
Irradiated whole-cell vaccine suppresses hepatocellular carcinoma growth in mice via Th9 cells.
Oncology letters
Chen J,Ding Y,Huang F,Lan R,Wang Z,Huang W,Chen R,Wu B,Fu L,Yang Y,Liu J,Hong J,Zhang W,Zhang L
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Neu-P11 - a novel melatonin receptor agonist, could improve the features of type-2 diabetes mellitus in rats.
Endokrynologia Polska
Li X,He J,Li X,Li Y,Zhou Y,Cai S
17-0032-82 was used in Flow Cytometry to investigate the effects of melatonin receptor agonist Neu-P11 on glucose metabolism, immunity, and islet function in type 2 diabetes mellitus rats.
Mon Mar 28 00:00:00 EDT 2022
Neuroimmune Consequences of eIF4E Phosphorylation on Chemotherapy-Induced Peripheral Neuropathy.
Frontiers in immunology
Agalave NM,Mody PH,Szabo-Pardi TA,Jeong HS,Burton MD
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Mon Sep 20 00:00:00 EDT 2021
Alphavirus-Driven Interferon Gamma (IFNg) Expression Inhibits Tumor Growth in Orthotopic 4T1 Breast Cancer Model.
Vaccines
Trofimova O,Korotkaja K,Skrastina D,Jansons J,Spunde K,Isaguliants M,Zajakina A
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Wed Oct 27 00:00:00 EDT 2021
Functional inhibition of lactate dehydrogenase suppresses pancreatic adenocarcinoma progression.
Clinical and translational medicine
Cheng CS,Tan HY,Wang N,Chen L,Meng Z,Chen Z,Feng Y
17-0032-82 was used in Immunohistochemistry to analyze the clinical-pathological characteristics and prognosis of 253 PAAD patients.
Tue Jun 01 00:00:00 EDT 2021
Functional inhibition of lactate dehydrogenase suppresses pancreatic adenocarcinoma progression.
Clinical and translational medicine
Cheng CS,Tan HY,Wang N,Chen L,Meng Z,Chen Z,Feng Y
17-0032-82 was used in Immunohistochemistry to analyze the clinical-pathological characteristics and prognosis of 253 PAAD patients.
Tue Jun 01 00:00:00 EDT 2021
Molecular Mechanisms Underpinning the Circulation and Cellular Uptake of Mycobacterium ulcerans Toxin Mycolactone.
Frontiers in pharmacology
Tello Rubio B,Bugault F,Baudon B,Raynal B,Brûlé S,Morel JD,Saint-Auret S,Blanchard N,Demangel C,Guenin-Macé L
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Tue Oct 05 00:00:00 EDT 2021
Expression of CCRL2 Inhibits Tumor Growth by Concentrating Chemerin and Inhibiting Neoangiogenesis.
Cancers
Al Delbany D,Robert V,Dubois-Vedrenne I,Del Prete A,Vernimmen M,Radi A,Lefort A,Libert F,Wittamer V,Sozzani S,Parmentier M
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Immunohistochemistry
Tue Oct 05 00:00:00 EDT 2021
Expression of CCRL2 Inhibits Tumor Growth by Concentrating Chemerin and Inhibiting Neoangiogenesis.
Cancers
Al Delbany D,Robert V,Dubois-Vedrenne I,Del Prete A,Vernimmen M,Radi A,Lefort A,Libert F,Wittamer V,Sozzani S,Parmentier M
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Immunohistochemistry
Tue Oct 05 00:00:00 EDT 2021
Small Molecule Potentiator of Adjuvant Activity Enhancing Survival to Influenza Viral Challenge.
Frontiers in immunology
Saito T,Sako Y,Sato-Kaneko F,Hosoya T,Yao S,Lao FS,Shpigelman J,Messer K,Pu M,Shukla NM,Chan M,Chu PJ,Cottam HB,Hayashi T,Carson DA,Corr M
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Fri Dec 10 00:00:00 EST 2021
Gut Microbiota Dysbiosis Induced by Intracerebral Hemorrhage Aggravates Neuroinflammation in Mice.
Frontiers in microbiology
Yu X,Zhou G,Shao B,Zhou H,Xu C,Yan F,Wang L,Chen G,Li J,Fu X
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Wed May 26 00:00:00 EDT 2021
Type 1 Cytotoxic T Cells Increase in Placenta after Intrauterine Inflammation.
Frontiers in immunology
Liu J,Liu Y,Panda S,Liu A,Lei J,Burd I
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Fri Dec 17 00:00:00 EST 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
Inducible T-Cell Costimulator Mediates Lymphocyte/Macrophage Interactions During Liver Repair.
Frontiers in immunology
Ramavath NN,Gadipudi LL,Provera A,Gigliotti LC,Boggio E,Bozzola C,Albano E,Dianzani U,Sutti S
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Mon Feb 14 00:00:00 EST 2022
External signals regulate continuous transcriptional states in hematopoietic stem cells.
eLife
Fast EM,Sporrij A,Manning M,Rocha EL,Yang S,Zhou Y,Guo J,Baryawno N,Barkas N,Scadden D,Camargo F,Zon LI
17-0032-82 was used in Flow cytometry/Cell sorting to compile a comprehensive resource of HSC- and LSK progenitor-specific chromatin and transcriptional features that represent determinants of signal receptiveness and regenerative potential during stress hematopoiesis.
Thu Dec 23 00:00:00 EST 2021
Exosome-mediated mRNA delivery in vivo is safe and can be used to induce SARS-CoV-2 immunity.
The Journal of biological chemistry
Tsai SJ,Atai NA,Cacciottolo M,Nice J,Salehi A,Guo C,Sedgwick A,Kanagavelu S,Gould SJ
17-0032-82 was used in Flow Cytometry to describe an alternative approach using exosomes, the only biologically normal nanovesicle.
Mon Nov 01 00:00:00 EDT 2021
The enrichment of neutrophil extracellular traps impair the placentas of systemic lupus erythematosus through accumulating decidual NK cells.
Scientific reports
Jiang M,Shen N,Zhou H,Wang Y,Lin S,Wu J,Di W
17-0032-82 was used in Flow Cytometry to show that NETs may contribute to immunological disorder in the placenta and the pathological changes in pregnancies with SLE, which provides a research basis for further explorations of the mechanism of SLE in placental impairment.
Thu Mar 25 00:00:00 EDT 2021
A macrophage-T cell coculture model for severe tissue injury-induced T cell death.
STAR protocols
Zhu J,Cao J,Liesz A,Roth S
17-0032-82 was used in Flow Cytometry to present an in vitro model for cell-cell interactions between innate (macrophages) and adaptive (T cells) immune cells.
Fri Dec 17 00:00:00 EST 2021
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
Single cell and tissue-transcriptomic analysis of murine bladders reveals age- and TNFα-dependent but microbiota-independent tertiary lymphoid tissue formation.
Mucosal immunology
Ligon MM,Wang C,DeJong EN,Schulz C,Bowdish DME,Mysorekar IU
17-0032 was used in Flow cytometry/Cell sorting to indicate that chronic, age-associated inflammation underlies a fundamental alteration to the bladder and establishes a resource for further investigation of the bladder immune system in homeostasis, aging, and disease.
Sun Nov 01 00:00:00 EDT 2020
Novel enhanced GFP-positive congenic inbred strain establishment and application of tumor-bearing nude mouse model.
Cancer science
Lan Q,Chen Y,Dai C,Li S,Fei X,Dong J,Shen Y,Dai X,Lu Z,Liu B,Wang Q,Wang H,Zhou Z,Ji X,Wang Z,Huang Q
17-0032 was used in Flow cytometry/Cell sorting to demonstrate that host cell malignant transformation and tumor/host cell fusion play an important role in tumor progression.
Thu Oct 01 00:00:00 EDT 2020
Novel enhanced GFP-positive congenic inbred strain establishment and application of tumor-bearing nude mouse model.
Cancer science
Lan Q,Chen Y,Dai C,Li S,Fei X,Dong J,Shen Y,Dai X,Lu Z,Liu B,Wang Q,Wang H,Zhou Z,Ji X,Wang Z,Huang Q
17-0032 was used in Flow cytometry/Cell sorting to demonstrate that host cell malignant transformation and tumor/host cell fusion play an important role in tumor progression.
Thu Oct 01 00:00:00 EDT 2020
In Situ Therapeutic Cancer Vaccination with an Oncolytic Virus Expressing Membrane-Tethered IL-2.
Molecular therapy oncolytics
Liu W,Dai E,Liu Z,Ma C,Guo ZS,Bartlett DL
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Fri Jun 26 00:00:00 EDT 2020
IL-13 Ameliorates Neuroinflammation and Promotes Functional Recovery after Traumatic Brain Injury.
Journal of immunology (Baltimore, Md. : 1950)
Miao W,Zhao Y,Huang Y,Chen D,Luo C,Su W,Gao Y
17-0032 was used in Flow cytometry/Cell sorting to demonstrate that IL-13 treatment improved neurologic outcomes after Traumatic Brain Injury through adjusting microglia/macrophage phenotypes and inhibiting inflammatory responses.
Sun Mar 15 00:00:00 EDT 2020
Evaluation of two methods to isolate Schwann cells from murine sciatic nerve.
Journal of neuroscience methods
Tomlinson JE,Golshadi M,Donahue CJ,Dong L,Cheetham J
17-0032 was used in Flow cytometry/Cell sorting to present two techniques to enrich schwann cells (SC) from other cell populations at the site of peripheral nerve injury.
Sat Feb 01 00:00:00 EST 2020
Neurokinin-1 Receptor Signaling Is Required for Efficient Ca2+ Flux in T-Cell-Receptor-Activated T Cells.
Cell reports
Morelli AE,Sumpter TL,Rojas-Canales DM,Bandyopadhyay M,Chen Z,Tkacheva O,Shufesky WJ,Wallace CT,Watkins SC,Berger A,Paige CJ,Falo LD,Larregina AT
17-0032 was used in Flow cytometry/Cell sorting to demonstrate an effect of the NK1R in T cells that is relevant for immunotherapies based on pro-inflammatory neuropeptides and its receptors.
Tue Mar 10 00:00:00 EDT 2020
Neurokinin-1 Receptor Signaling Is Required for Efficient Ca2+ Flux in T-Cell-Receptor-Activated T Cells.
Cell reports
Morelli AE,Sumpter TL,Rojas-Canales DM,Bandyopadhyay M,Chen Z,Tkacheva O,Shufesky WJ,Wallace CT,Watkins SC,Berger A,Paige CJ,Falo LD,Larregina AT
17-0032 was used in Flow cytometry/Cell sorting to demonstrate an effect of the NK1R in T cells that is relevant for immunotherapies based on pro-inflammatory neuropeptides and its receptors.
Tue Mar 10 00:00:00 EDT 2020
Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.
JCI insight
Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Thu Aug 20 00:00:00 EDT 2020
Triptolide Attenuates Transplant Vasculopathy Through Multiple Pathways.
Frontiers in immunology
Luo Z,Liao T,Zhang Y,Zheng H,Sun Q,Han F,Yang Z,Sun Q
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Thu Mar 25 00:00:00 EDT 2021
Mesenchymal stem cells protect against malaria pathogenesis by reprogramming erythropoiesis in the bone marrow.
Cell death discovery
Thakur RS,Awasthi V,Sanyal A,Chatterjee S,Rani S,Chauhan R,Kalkal M,Tiwari M,Pande V,Das J
17-0032 was used in Flow cytometry/Cell sorting to suggest that MSCs play a critical role in host protection against malaria infection by modulating erythropoiesis and lymphopoiesis.
Sun Nov 15 00:00:00 EST 2020
Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer.
Nature communications
Buqué A,Bloy N,Perez-Lanzón M,Iribarren K,Humeau J,Pol JG,Levesque S,Mondragon L,Yamazaki T,Sato A,Aranda F,Durand S,Boissonnas A,Fucikova J,Senovilla L,Enot D,Hensler M,Kremer M,Stoll G,Hu Y,Massa C,Formenti SC,Seliger B,Elemento O,Spisek R,André F,Zitvogel L,Delaloge S,Kroemer G,Galluzzi L
17-0032 was used in Flow cytometry/Cell sorting to identify NAM as a potential strategy for the prevention and treatment of HR+ BC.
Thu Jul 30 00:00:00 EDT 2020
MicroRNA-200a induces immunosuppression by promoting PTEN-mediated PD-L1 upregulation in osteosarcoma.
Aging
Liu Z,Wen J,Wu C,Hu C,Wang J,Bao Q,Wang H,Wang J,Zhou Q,Wei L,Shen Y,Zhang W
17-0032 was used in Flow cytometry/Cell sorting to provide important and novel insight into a regulatory axis involving microRNA-200a/PTEN/ PD-L1 axis, which determines osteosarcoma growth and the efficacy of PD-L1-targeted immunotherapy.
Fri Jan 24 00:00:00 EST 2020
Rhein modulates host purine metabolism in intestine through gut microbiota and ameliorates experimental colitis.
Theranostics
Wu J,Wei Z,Cheng P,Qian C,Xu F,Yang Y,Wang A,Chen W,Sun Z,Lu Y
17-0032 was used in Flow cytometry/Cell sorting to investigate the effect of rhein on colitis and studied its possible mechanisms.
Mon May 31 00:00:00 EDT 2021
Curative in vivo hematopoietic stem cell gene therapy of murine thalassemia using large regulatory elements.
JCI insight
Wang H,Georgakopoulou A,Li C,Liu Z,Gil S,Bashyam A,Yannaki E,Anagnostopoulos A,Pande A,Izsvák Z,Papayannopoulou T,Lieber A
17-0032 was used in Flow cytometry/Cell sorting to demonstrate that hematopoietic stem/progenitor cell (HSPC) mobilization followed by intravenous injection of integrating, helper-dependent adenovirus HDAd5/35++ vectors resulted in efficient transduction of long-term repopulating cells and disease amelioration in mouse models after in vivo selection of transduced HSPCs.
Thu Aug 20 00:00:00 EDT 2020
Therapeutic paradigm of dual targeting VEGF and PDGF for effectively treating FGF-2 off-target tumors.
Nature communications
Hosaka K,Yang Y,Seki T,Du Q,Jing X,He X,Wu J,Zhang Y,Morikawa H,Nakamura M,Scherzer M,Sun X,Xu Y,Cheng T,Li X,Liu X,Li Q,Liu Y,Hong A,Chen Y,Cao Y
17-0032 was used in Flow cytometry/Cell sorting to show that FGF-2 modulates tumor vessels by recruiting NG2+ pricytes onto tumor microvessels through a PDGFRβ-dependent mechanism.
Fri Jul 24 00:00:00 EDT 2020
Therapeutic paradigm of dual targeting VEGF and PDGF for effectively treating FGF-2 off-target tumors.
Nature communications
Hosaka K,Yang Y,Seki T,Du Q,Jing X,He X,Wu J,Zhang Y,Morikawa H,Nakamura M,Scherzer M,Sun X,Xu Y,Cheng T,Li X,Liu X,Li Q,Liu Y,Hong A,Chen Y,Cao Y
17-0032 was used in Flow cytometry/Cell sorting to show that FGF-2 modulates tumor vessels by recruiting NG2+ pricytes onto tumor microvessels through a PDGFRβ-dependent mechanism.
Fri Jul 24 00:00:00 EDT 2020
CD8+ T cells induce cachexia during chronic viral infection.
Nature immunology
Baazim H,Schweiger M,Moschinger M,Xu H,Scherer T,Popa A,Gallage S,Ali A,Khamina K,Kosack L,Vilagos B,Smyth M,Lercher A,Friske J,Merkler D,Aderem A,Helbich TH,Heikenwälder M,Lang PA,Zechner R,Bergthaler A
17-0032-82 was used in Flow Cytometry to identify the role for CD8+ T cells in infection-associated cachexia.
Sat Jun 01 00:00:00 EDT 2019
Type I interferon induces CXCL13 to support ectopic germinal center formation.
The Journal of experimental medicine
Denton AE,Innocentin S,Carr EJ,Bradford BM,Lafouresse F,Mabbott NA,Mörbe U,Ludewig B,Groom JR,Good-Jacobson KL,Linterman MA
17-0032-82 was used in Immunohistochemistry to identify type I interferon as a novel inducer of CXCL13, which, in combination with other stimuli, can promote lung remodeling, converting a nonlymphoid tissue into one permissive to functional tertiary lymphoid structure formation.
Mon Mar 04 00:00:00 EST 2019
miR-146a Controls Immune Response in the Melanoma Microenvironment.
Cancer research
Mastroianni J,Stickel N,Andrlova H,Hanke K,Melchinger W,Duquesne S,Schmidt D,Falk M,Andrieux G,Pfeifer D,Dierbach H,Schmitt-Graeff A,Meiss F,Boerries M,Zeiser R
17-0032-82 was used in Flow Cytometry to identify miR-146a as a negative regulator of immune activation, comparable to immune-checkpoint molecules.
Tue Jan 01 00:00:00 EST 2019
Epigenetically modulated FOXM1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer.
Molecular oncology
Zhou Z,Chen H,Xie R,Wang H,Li S,Xu Q,Xu N,Cheng Q,Qian Y,Huang R,Shao Z,Xiang M
17-0032 was used in Flow cytometry/Cell sorting to show that upregulation of FOXM1 by H3K79me2 in pancreatic cancer and colon cancer significantly inhibits maturation phenotypes and function of bone marrow dendritic cells (BMDCs) through the Wnt5a signaling pathway, and thus provide novel insights into FOXM1-based antitumor immunotherapy.
Mon Apr 01 00:00:00 EDT 2019
Expression of Bioactive Chemerin by Keratinocytes Inhibits Late Stages of Tumor Development in a Chemical Model of Skin Carcinogenesis.
Frontiers in oncology
Dubois-Vedrenne I,De Henau O,Robert V,Langa F,Javary J,Al Delbany D,Vosters O,Angelats-Canals E,Vernimmen M,Luangsay S,Wittamer V,Parmentier M
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
Deletion of C-C Motif Chemokine Ligand 5 Worsens Invariant Natural Killer T-Cell-Mediated Hepatitis via Compensatory Up-regulation of CXCR2-Related Chemokine Activity.
Cellular and molecular gastroenterology and hepatology
Chen L,Gu J,Qian Y,Li M,Qian Y,Xu M,Li J,Wen Y,Xia L,Li J,Xia Q,Kong X,Wu H
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Tue Jun 04 00:00:00 EDT 2019
Blood autophagy defect causes accelerated non-hematopoietic organ aging.
Aging
Fang Y,Zhu L,An N,Jiang G,Qian J,Zhao R,Yuan N,Zhang S,Wang J
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Sun Jul 21 00:00:00 EDT 2019
MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.
Journal for immunotherapy of cancer
Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Thu Nov 28 00:00:00 EST 2019
LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy.
Nature communications
Pascual-García M,Bonfill-Teixidor E,Planas-Rigol E,Rubio-Perez C,Iurlaro R,Arias A,Cuartas I,Sala-Hojman A,Escudero L,Martínez-Ricarte F,Huber-Ruano I,Nuciforo P,Pedrosa L,Marques C,Braña I,Garralda E,Vieito M,Squatrito M,Pineda E,Graus F,Espejo C,Sahuquillo J,Tabernero J,Seoane J
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Tue Jun 11 00:00:00 EDT 2019
LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy.
Nature communications
Pascual-García M,Bonfill-Teixidor E,Planas-Rigol E,Rubio-Perez C,Iurlaro R,Arias A,Cuartas I,Sala-Hojman A,Escudero L,Martínez-Ricarte F,Huber-Ruano I,Nuciforo P,Pedrosa L,Marques C,Braña I,Garralda E,Vieito M,Squatrito M,Pineda E,Graus F,Espejo C,Sahuquillo J,Tabernero J,Seoane J
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Tue Jun 11 00:00:00 EDT 2019
Mutations in topoisomerase IIβ result in a B cell immunodeficiency.
Nature communications
Broderick L,Yost S,Li D,McGeough MD,Booshehri LM,Guaderrama M,Brydges SD,Kucharova K,Patel NC,Harr M,Hakonarson H,Zackai E,Cowell IG,Austin CA,Hügle B,Gebauer C,Zhang J,Xu X,Wang J,Croker BA,Frazer KA,Putnam CD,Hoffman HM
17-0032-82 was used in Flow Cytometry to identify mutations in type II topoisomerase as a driver of defective proliferation and survival of B2 cells, leading to a B cell immunodeficiency.
Tue Aug 13 00:00:00 EDT 2019
The BtaF Adhesin Is Necessary for Full Virulence During Respiratory Infection by Brucella suis and Is a Novel Immunogen for Nasal Vaccination Against Brucella Infection.
Frontiers in immunology
Muñoz González F,Sycz G,Alonso Paiva IM,Linke D,Zorreguieta A,Baldi PC,Ferrero MC
17-0032-82 was used in Flow Cytometry to evaluate the importance of BtaF for respiratory Brucella infection, and to characterize the immune response induced by nasal vaccination with recombinant BtaF.
Tue Oct 13 00:00:00 EDT 2020
The IRE1α Arm of UPR Regulates Muscle Cells Immune Characters by Restraining p38 MAPK Activation.
Frontiers in physiology
Gu R,Huang T,Xiao J,Liao Z,Li J,Lan H,Ouyang J,Hu J,Liao H
17-0032-82 was used in Flow Cytometry to demonstrate that p38 MAPK contributes greatly to IRE1α arm-dependent immunobiological suppression in myocytes under inflammatory stress conditions.
Wed Sep 30 00:00:00 EDT 2020
N-Cadherin-Expressing Bone and Marrow Stromal Progenitor Cells Maintain Reserve Hematopoietic Stem Cells.
Cell reports
Zhao M,Tao F,Venkatraman A,Li Z,Smith SE,Unruh J,Chen S,Ward C,Qian P,Perry JM,Marshall H,Wang J,He XC,Li L
17-0032 was used in Flow cytometry/Cell sorting to report that N-cad+ cells were functional bone and marrow stromal progenitor cells, giving rise to osteoblasts, adipocytes, and chondrocytes both in vitro and in vivo.
Tue Jan 15 00:00:00 EST 2019
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
Insulin resistance causes inflammation in adipose tissue.
The Journal of clinical investigation
Shimobayashi M,Albert V,Woelnerhanssen B,Frei IC,Weissenberger D,Meyer-Gerspach AC,Clement N,Moes S,Colombi M,Meier JA,Swierczynska MM,Jenö P,Beglinger C,Peterli R,Hall MN
17-0032 was used in Flow cytometry/Cell sorting to elucidate the causal relationship between obesity-induced insulin resistance, and macrophage accumulation and inflammation in adipose tissue.
Mon Apr 02 00:00:00 EDT 2018
Impact of hyperglycemia on autoimmune pancreatitis and regulatory T-cells.
World journal of gastroenterology
Müller-Graff FT,Fitzner B,Jaster R,Vollmar B,Zechner D
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Sat Jul 28 00:00:00 EDT 2018
Neonatal adoptive transfer of lymphocytes rescues social behaviour during adolescence in immune-deficient mice.
The European journal of neuroscience
Clark SM,Vaughn CN,Soroka JA,Li X,Tonelli LH
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
CD4+ T cells are activated in regional lymph nodes and migrate to skin to initiate lymphedema.
Nature communications
García Nores GD,Ly CL,Cuzzone DA,Kataru RP,Hespe GE,Torrisi JS,Huang JJ,Gardenier JC,Savetsky IL,Nitti MD,Yu JZ,Rehal S,Mehrara BJ
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Thu May 17 00:00:00 EDT 2018
Microglia prevent peripheral immune cell invasion and promote an anti-inflammatory environment in the brain of APP-PS1 transgenic mice.
Journal of neuroinflammation
Unger MS,Schernthaner P,Marschallinger J,Mrowetz H,Aigner L
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Fri Sep 21 00:00:00 EDT 2018
Microglia prevent peripheral immune cell invasion and promote an anti-inflammatory environment in the brain of APP-PS1 transgenic mice.
Journal of neuroinflammation
Unger MS,Schernthaner P,Marschallinger J,Mrowetz H,Aigner L
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Fri Sep 21 00:00:00 EDT 2018
Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice.
mSphere
Quach D,Collins F,Parameswaran N,McCabe L,Britton RA
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Tue Dec 11 00:00:00 EST 2018
Trichinella spiralis Infection Mitigates Collagen-Induced Arthritis via Programmed Death 1-Mediated Immunomodulation.
Frontiers in immunology
Cheng Y,Zhu X,Wang X,Zhuang Q,Huyan X,Sun X,Huang J,Zhan B,Zhu X
Mon Jan 28 00:00:00 EST 2019
A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors.
Nature communications
Vigolo M,Chambers MG,Willen L,Chevalley D,Maskos K,Lammens A,Tardivel A,Das D,Kowalczyk-Quintas C,Schuepbach-Mallepell S,Smulski CR,Eslami M,Rolink A,Hummler E,Samy E,Fomekong Nanfack Y,Mackay F,Liao M,Hess H,Jiang X,Schneider P
17-0032 was used in Flow cytometry/Cell sorting to study TNSF13B/BAFF interactions in C57BL/6OlaHsd mice. TNSF13B/BAFF underwent flow cytometry to investigate if distint biological and clinical efficacies occur to the therapeutically relevant inhibitors.
Fri Mar 23 00:00:00 EDT 2018
Neonatally imprinted stromal cell subsets induce tolerogenic dendritic cells in mesenteric lymph nodes.
Nature communications
Pezoldt J,Pasztoi M,Zou M,Wiechers C,Beckstette M,Thierry GR,Vafadarnejad E,Floess S,Arampatzi P,Buettner M,Schweer J,Fleissner D,Vital M,Pieper DH,Basic M,Dersch P,Strowig T,Hornef M,Bleich A,Bode U,Pabst O,Bajénoff M,Saliba AE,Huehn J
Tue Sep 25 00:00:00 EDT 2018
Necroptosis of infiltrated macrophages drives Yersinia pestis dispersal within buboes.
JCI insight
Arifuzzaman M,Ang WXG,Choi HW,Nilles ML,St John AL,Abraham SN
17-0032-82 was used in Flow Cytometry to examine how Yersinia pestis converts immunocytes recruited by host to contain the pathogen into vehicles for bacterial dispersal and the role of immune cell death in this context.
Thu Sep 20 00:00:00 EDT 2018
Estriol Reduces Pulmonary Immune Cell Recruitment and Inflammation to Protect Female Mice From Severe Influenza.
Endocrinology
Vermillion MS,Ursin RL,Attreed SE,Klein SL
17-0032-82 was used in Flow cytometry/Cell sorting to suggest that exogenous E3 confers protection during IAV infection through immunomodulatory mechanisms and that E3 may have broad therapeutic potential in the context of both infectious and noninfectious inflammatory diseases.
Sat Sep 01 00:00:00 EDT 2018
Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.
Nature
Hérault A,Binnewies M,Leong S,Calero-Nieto FJ,Zhang SY,Kang YA,Wang X,Pietras EM,Chu SH,Barry-Holson K,Armstrong S,Göttgens B,Passegué E
17-0032 was used in Flow cytometry/Cell sorting to show that in leukaemia, GMP clusters are constantly produced due to lack of termination cytokines that restore haematopoietic stem-cell quiescence.
Thu Apr 06 00:00:00 EDT 2017
Autophagy maintains the metabolism and function of young and old stem cells.
Nature
Ho TT,Warr MR,Adelman ER,Lansinger OM,Flach J,Verovskaya EV,Figueroa ME,Passegué E
17-0032 was used in Flow cytometry/Cell sorting to demonstrate an essential function for autophagy in removing activated mitochondria and controlling oxidative metabolism, thereby maintaining HSC stemness and regenerative potential.
Thu Mar 09 00:00:00 EST 2017
Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation.
Cell
Wang S,Xia P,Chen Y,Qu Y,Xiong Z,Ye B,Du Y,Tian Y,Yin Z,Xu Z,Fan Z
17-0032 was used in Immunocytochemistry to identify a regulatory subpopulation of innate lymphoid cells that exists in the gut, and harbour a unique gene identity.
Thu Sep 21 00:00:00 EDT 2017
Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation.
Cell
Wang S,Xia P,Chen Y,Qu Y,Xiong Z,Ye B,Du Y,Tian Y,Yin Z,Xu Z,Fan Z
17-0032 was used in Immunocytochemistry to identify a regulatory subpopulation of innate lymphoid cells that exists in the gut, and harbour a unique gene identity.
Thu Sep 21 00:00:00 EDT 2017
ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control.
The Journal of experimental medicine
Schwartz C,Khan AR,Floudas A,Saunders SP,Hams E,Rodewald HR,McKenzie ANJ,Fallon PG
17-0032 was used in Flow cytometry/Cell sorting to study how group 2 innate lymphoid cells regulate adaptive Th2 cell functions.
Mon Sep 04 00:00:00 EDT 2017
Discovery and characterization of a novel humanized anti-IL-15 antibody and its relevance for the treatment of refractory celiac disease and eosinophilic esophagitis.
mAbs
Vicari AP,Schoepfer AM,Meresse B,Goffin L,Léger O,Josserand S,Guégan N,Yousefi S,Straumann A,Cerf-Bensussan N,Simon HU,Chvatchko Y
17-0032 was used in Flow cytometry/Cell sorting to identify and characterise a humanised antibody against IL-15.
Wed Nov 20 00:00:00 EST 2019
Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-κB signaling and NLRP3 activation.
International journal of molecular medicine
Zhang B,Wang B,Cao S,Wang Y,Wu D
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
ImmunoPET Imaging of Murine CD4+ T Cells Using Anti-CD4 Cys-Diabody: Effects of Protein Dose on T Cell Function and Imaging.
Molecular imaging and biology
Freise AC,Zettlitz KA,Salazar FB,Lu X,Tavaré R,Wu AM
17-0032 was used in Flow cytometry/Cell sorting to test GK1.5 cys-diabody, a previously developed anti-mouse CD4 antibody fragment, to assess its effects on positron emission tomography imaging and CD4+ T cell viability, proliferation, CD4 expression, and function.
Tue Aug 01 00:00:00 EDT 2017
Effect of Early-life Gut Mucosal Compromise on Disease Progression in NOD Mice.
Comparative medicine
Bendtsen KM,Hansen CH,Krych L,Buschard K,Farlov H,Hansen AK
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells.
Oncotarget
Guo XL,Chu L,Ke F,Mu LL,Li Z,Cai JJ,Li HF,Hong DL
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Tue Dec 12 00:00:00 EST 2017
Loss of epidermal AP1 transcription factor function reduces filaggrin level, alters chemokine expression and produces an ichthyosis-related phenotype.
Cell death & disease
Young CA,Rorke EA,Adhikary G,Xu W,Eckert RL
Thu Jun 01 00:00:00 EDT 2017
Tristetraprolin inhibits macrophage IL-27-induced activation of antitumour cytotoxic T cell responses.
Nature communications
Wang Q,Ning H,Peng H,Wei L,Hou R,Hoft DF,Liu J
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Wed Oct 11 00:00:00 EDT 2017
Rottlerin as a therapeutic approach in psoriasis: Evidence from in vitro and in vivo studies.
PloS one
Min M,Yan BX,Wang P,Landeck L,Chen JQ,Li W,Cai SQ,Zheng M,Man XY
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Tue Jan 16 00:00:00 EST 2018
Respiratory Syncytial Virus Exacerbates OVA-mediated asthma in mice through C5a-C5aR regulating CD4+T cells Immune Responses.
Scientific reports
Hu X,Li X,Hu C,Qin L,He R,Luo L,Tang W,Feng J
17-0032 was used in Flow cytometry/Cell sorting to indicate that respiratory syncytial virus infection can increase C5a and C5aR expression in the pathogenesis of infected, asthmatic mice.
Thu Nov 09 00:00:00 EST 2017
Liver microRNA-21 is overexpressed in non-alcoholic steatohepatitis and contributes to the disease in experimental models by inhibiting PPARα expression.
Gut
Loyer X,Paradis V,Hénique C,Vion AC,Colnot N,Guerin CL,Devue C,On S,Scetbun J,Romain M,Paul JL,Rothenberg ME,Marcellin P,Durand F,Bedossa P,Prip-Buus C,Baugé E,Staels B,Boulanger CM,Tedgui A,Rautou PE
17003282 was used in flow cytometry to delineate the role of microRNA-21 in non-alcoholic steatohepatitis
Tue Nov 01 00:00:00 EDT 2016
Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal.
Nature cell biology
Pietras EM,Mirantes-Barbeito C,Fong S,Loeffler D,Kovtonyuk LV,Zhang S,Lakshminarasimhan R,Chin CP,Techner JM,Will B,Nerlov C,Steidl U,Manz MG,Schroeder T,Passegué E
17-0032 was used in Flow cytometry/Cell sorting to identify a critical regulatory circuit that tailors HSC responses to acute needs, and is likely to underlie deregulated blood homeostasis in chronic inflammation conditions.
Wed Jun 01 00:00:00 EDT 2016
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
An Effective Immuno-PET Imaging Method to Monitor CD8-Dependent Responses to Immunotherapy.
Cancer research
Tavaré R,Escuin-Ordinas H,Mok S,McCracken MN,Zettlitz KA,Salazar FB,Witte ON,Ribas A,Wu AM
17-0032 was used in Flow cytometry/Cell sorting to investigate anti-CD8 immuno-PET as a sensitive tool for tracking systemic and tumour-infiltrating CD8+ T cell expression in tumour immunotherapy models.
Fri Jan 01 00:00:00 EST 2016
Investigating palygorskite's role in the development of mesothelioma in southern Nevada: Insights into fiber-induced carcinogenicity.
Journal of toxicology and environmental health. Part B, Critical reviews
Larson D,Powers A,Ambrosi JP,Tanji M,Napolitano A,Flores EG,Baumann F,Pellegrini L,Jennings CJ,Buck BJ,McLaurin BT,Merkler D,Robinson C,Morris P,Dogan M,Dogan AU,Pass HI,Pastorino S,Carbone M,Yang H
17-0032 was used in Flow cytometry/Cell sorting to determine whether palygorskite contributes to the development of malignant mesothelioma in southern Nevada.
Fri May 26 00:00:00 EDT 2017
Characterization of a novel MR-detectable nanoantioxidant that mitigates the recall immune response.
NMR in biomedicine
Inoue T,Griffin DM,Huq R,Samuel EL,Ruano SH,Stinnett G,Majid TJ,Beeton C,Tour JM,Pautler RG
17-0032 was used in Flow cytometry/Cell sorting to characterise Gd-DTPA conjugated nano-antioxidant (PEG-HCCs) and explores the potential for in vivo tracking and ROS suppression of T cells in live mice.
Sat Oct 01 00:00:00 EDT 2016
CD8(+) T-cell Immune Evasion Enables Oncolytic Virus Immunotherapy.
EBioMedicine
Pourchet A,Fuhrmann SR,Pilones KA,Demaria S,Frey AB,Mulvey M,Mohr I
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Nature communications
Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Wed Sep 07 00:00:00 EDT 2016
TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection.
Cell reports
Schleicher U,Paduch K,Debus A,Obermeyer S,König T,Kling JC,Ribechini E,Dudziak D,Mougiakakos D,Murray PJ,Ostuni R,Körner H,Bogdan C
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Tue May 03 00:00:00 EDT 2016
Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.
Scientific reports
Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Wed Jun 15 00:00:00 EDT 2016
Antibodies That Block or Activate Mouse B Cell Activating Factor of the Tumor Necrosis Factor (TNF) Family (BAFF), Respectively, Induce B Cell Depletion or B Cell Hyperplasia.
The Journal of biological chemistry
Kowalczyk-Quintas C,Schuepbach-Mallepell S,Vigolo M,Willen L,Tardivel A,Smulski CR,Zheng TS,Gommerman J,Hess H,Gottenberg JE,Mackay F,Donzé O,Schneider P
17-0032 was used in Flow cytometry/Cell sorting to investigate the ability of different monoclonal antibodies to recognize, inhibit, or activate mouse BAFF.
Fri Sep 16 00:00:00 EDT 2016
IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis.
The Journal of experimental medicine
Pallangyo CK,Ziegler PK,Greten FR
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Mon Dec 14 00:00:00 EST 2015
Adjuvants may reduce in vivo transfection levels for DNA vaccination in mice leading to reduced antigen-specific CD8+ T cell responses.
Human vaccines & immunotherapeutics
Rose AH,Hoffmann FW,Hara JH,Urschitz J,Moisyadi S,Hoffmann PR,Bertino P
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Mon May 16 00:00:00 EDT 2016
IL-33 Enhances Humoral Immunity Against Chronic HBV Infection Through Activating CD4(+)CXCR5(+) TFH Cells.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Zhao PW,Shi X,Li C,Ayana DA,Niu JQ,Feng JY,Wang J,Jiang YF
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling.
Nature communications
Kang YJ,Bang BR,Han KH,Hong L,Shim EJ,Ma J,Lerner RA,Otsuka M
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Fri Sep 18 00:00:00 EDT 2015
Antibiotics in neonatal life increase murine susceptibility to experimental psoriasis.
Nature communications
Zanvit P,Konkel JE,Jiao X,Kasagi S,Zhang D,Wu R,Chia C,Ajami NJ,Smith DP,Petrosino JF,Abbatiello B,Nakatsukasa H,Chen Q,Belkaid Y,Chen ZJ,Chen W
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2015
H9N2 influenza whole inactivated virus combined with polyethyleneimine strongly enhances mucosal and systemic immunity after intranasal immunization in mice.
Clinical and vaccine immunology : CVI
Qin T,Yin Y,Huang L,Yu Q,Yang Q
17-0032 was used in Flow cytometry/Cell sorting to investigate the immune activity of polyethyleneimine with H9N2 influenza whole inactivated virus, showing that it enhances mucosal and systemic immunity after intranasal immunization.
Wed Apr 01 00:00:00 EDT 2015
Dendritic Cell Autophagy Contributes to Herpes Simplex Virus-Driven Stromal Keratitis and Immunopathology.
mBio
Jiang Y,Yin X,Stuart PM,Leib DA
17-0032 was used in Flow cytometry/Cell sorting to broaden our understanding of the immunopathology that drives HSK.
Tue Oct 27 00:00:00 EDT 2015
Stoichiometry of Heteromeric BAFF and APRIL Cytokines Dictates Their Receptor Binding and Signaling Properties.
The Journal of biological chemistry
Schuepbach-Mallepell S,Das D,Willen L,Vigolo M,Tardivel A,Lebon L,Kowalczyk-Quintas C,Nys J,Smulski C,Zheng TS,Maskos K,Lammens A,Jiang X,Hess H,Tan SL,Schneider P
17-0032 was used in Flow cytometry/Cell sorting to study how BAFF-APRIL heteromers of different stoichiometries have distinct receptor-binding properties and activities.
Fri Jun 26 00:00:00 EDT 2015
Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity.
Nature
Westphalen K,Gusarova GA,Islam MN,Subramanian M,Cohen TS,Prince AS,Bhattacharya J
17-0032 was used in Flow cytometry/Cell sorting to show that a subset of alveolar macrophages (AMs) attached to the alveolar wall form connexin 43 (Cx43)-containing gap junction channels with the epithelium.
Thu Feb 27 00:00:00 EST 2014
Chronic exposure to type-I IFN under lymphopenic conditions alters CD4 T cell homeostasis.
PLoS pathogens
Le Saout C,Hasley RB,Imamichi H,Tcheung L,Hu Z,Luckey MA,Park JH,Durum SK,Smith M,Rupert AW,Sneller MC,Lane HC,Catalfamo M
17-0032 was used in Flow cytometry/Cell sorting to define the mechanisms behind immune cell maintenance in HIV infected individuals.
Sat Mar 01 00:00:00 EST 2014
Depletion of myeloid-derived suppressor cells during interleukin-12 immunogene therapy does not confer a survival advantage in experimental malignant glioma.
Cancer gene therapy
Thaci B,Ahmed AU,Ulasov IV,Wainwright DA,Nigam P,Auffinger B,Tobias AL,Han Y,Zhang L,Moon KS,Lesniak MS
17-0032 was used in Flow cytometry/Cell sorting to investigate how MDSC depletion can affect glioma immunotherapy, showing that it does not confer a survival advantage.
Wed Jan 01 00:00:00 EST 2014
Innate PI3K p110δ regulates Th1/Th17 development and microbiota-dependent colitis.
Journal of immunology (Baltimore, Md. : 1950)
Steinbach EC,Kobayashi T,Russo SM,Sheikh SZ,Gipson GR,Kennedy ST,Uno JK,Mishima Y,Borst LB,Liu B,Herfarth H,Ting JP,Sartor RB,Plevy SE
17-0032 was used in Flow cytometry/Cell sorting to explore the role of IL-10 and IL-12/23 in the development of microbiota-dependent colitis.
Tue Apr 15 00:00:00 EDT 2014
A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking β-glucans.
PloS one
Dong B,Li D,Li R,Chen SC,Liu W,Liu W,Chen L,Chen Y,Zhang X,Tong Z,Xia Y,Xia P,Wang Y,Duan Y
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2015
Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface.
PloS one
Habbeddine M,Verbeke P,Karaz S,Bobé P,Kanellopoulos-Langevin C
Published figure using CD3 monoclonal antibody (Product # 17-0032-82) in Flow Cytometry
Wed Jun 10 00:00:00 EDT 2015
Three weeks of murine hindlimb unloading induces shifts from B to T and from th to tc splenic lymphocytes in absence of stress and differentially reduces cell-specific mitogenic responses.
PloS one
Gaignier F,Schenten V,De Carvalho Bittencourt M,Gauquelin-Koch G,Frippiat JP,Legrand-Frossi C
17-0032 was used in Functional assays to suggest that B cells are more affected by hindlimb unloading than T cells, which may explain the high susceptibility to pathogens.
Thu Jan 15 00:00:00 EST 2015
An orally active immune adjuvant prepared from cones of Pinus sylvestris, enhances the proliferative phase of a primary T cell response.
BMC complementary and alternative medicine
Bradley WG,Holm KN,Tanaka A
17-0032 was used in Flow cytometry/Cell sorting to investigate the mechanism by which polyphenylpropanoid polysaccharide complex enhances the proliferative phase of a primary T cell response.
Thu May 22 00:00:00 EDT 2014
B lymphocytes trigger monocyte mobilization and impair heart function after acute myocardial infarction.
Nature medicine
Zouggari Y,Ait-Oufella H,Bonnin P,Simon T,Sage AP,Guérin C,Vilar J,Caligiuri G,Tsiantoulas D,Laurans L,Dumeau E,Kotti S,Bruneval P,Charo IF,Binder CJ,Danchin N,Tedgui A,Tedder TF,Silvestre JS,Mallat Z
17-0032 was used in Flow cytometry/Cell sorting to identify the interaction between mature B lymphocytes and monocytes as a potential therapeutic target after a heart attack.
Tue Oct 01 00:00:00 EDT 2013
Genome-wide mouse mutagenesis reveals CD45-mediated T cell function as critical in protective immunity to HSV-1.
PLoS pathogens
Caignard G,Leiva-Torres GA,Leney-Greene M,Charbonneau B,Dumaine A,Fodil-Cornu N,Pyzik M,Cingolani P,Schwartzentruber J,Dupaul-Chicoine J,Guo H,Saleh M,Veillette A,Lathrop M,Blanchette M,Majewski J,Pearson A,Vidal SM
17-0032 was used in Flow cytometry/Cell sorting to identify host factors involved in HSV-1 and herpes simplex encephalitis susceptibility in an in vivo HSV-1 infectious model.
Sun Sep 01 00:00:00 EDT 2013
Two-photon microscopy imaging of thy1GFP-M transgenic mice: a novel animal model to investigate brain dendritic cell subsets in vivo.
PloS one
Laperchia C,Allegra Mascaro AL,Sacconi L,Andrioli A,Mattè A,De Franceschi L,Grassi-Zucconi G,Bentivoglio M,Buffelli M,Pavone FS
17-0032 was used in Flow cytometry/Cell sorting to employ a transgenic mouse model to study professional antigen-presenting cells in the brain.
Mon Jul 29 00:00:00 EDT 2013
NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors.
Nature medicine
Alvarez-Breckenridge CA,Yu J,Price R,Wojton J,Pradarelli J,Mao H,Wei M,Wang Y,He S,Hardcastle J,Fernandez SA,Kaur B,Lawler SE,Vivier E,Mandelboim O,Moretta A,Caligiuri MA,Chiocca EA
17-0032 was used in Flow cytometry/Cell sorting to demonstrate that glioblastoma virotherapy is limited partially by an antiviral NK cell response involving specific NCRs, uncovering new potential targets to enhance cancer virotherapy.
Sat Dec 01 00:00:00 EST 2012
NF-Y is necessary for hematopoietic stem cell proliferation and survival.
Blood
Bungartz G,Land H,Scadden DT,Emerson SG
17-0032 was used in Flow cytometry/Cell sorting to show that the trimeric transcription factor NF-Y is critical for the survival of cycling, but not quiescent hematopoietic stem cells.
Thu Feb 09 00:00:00 EST 2012
Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice.
The Journal of experimental medicine
Christopher MJ,Rao M,Liu F,Woloszynek JR,Link DC
17-0032 was used in Flow cytometry/Cell sorting to suggest a model in which G-CSFR signals in bone marrow monocytic cells inhibit the production of trophic factors required for osteoblast lineage cell maintenance.
Mon Feb 14 00:00:00 EST 2011
RNA interference-mediated silencing of Foxo3 in antigen-presenting cells as a strategy for the enhancement of DNA vaccine potency.
Gene therapy
Wang ST,Chang CC,Yen MC,Tu CF,Chu CL,Peng YT,Chen DY,Lan JL,Lin CC
17-0032 was used in Flow cytometry/Cell sorting to study whether silencing Foxo3 enhances the antitumour immunity of cancer vaccines.
Fri Apr 01 00:00:00 EDT 2011
