Product References
Sex-specific differences in T-cell immune dysregulation and aberrant response to inflammatory stimuli in offspring exposed to maternal chronic inflammation.
American journal of reproductive immunology (New York, N.Y. : 1989)
Liu J,Liu Y,Kirschen G,Liu A,Lei J,Burd I
48-0032-82 was used in Flow cytometry/Cell sorting to investigate how MI affects the T-cell immune development from the fetal to the neonatal period and how offspring responded to postnatal IL-1β challenge when exposed to an adverse intrauterine environment.
Wed Mar 01 00:00:00 EST 2023
Differential requirement of neutralizing antibodies and T cells on protective immunity to SARS-CoV-2 variants of concern.
NPJ vaccines
Azevedo PO,Hojo-Souza NS,Faustino LP,Fumagalli MJ,Hirako IC,Oliveira ER,Figueiredo MM,Carvalho AF,Doro D,Benevides L,Durigon E,Fonseca F,Machado AM,Fernandes AP,Teixeira SR,Silva JS,Gazzinelli RT
48-0032-82 was used in Flow cytometry/Cell sorting to evaluate the efficacy of a Spike-based DNA vaccine (pCTV-WS) for protection against different VOCs using existing pre-clinical models of severe and moderate COVID-19.
Mon Feb 13 00:00:00 EST 2023
Deletion of CD36 exhibits limited impact on normal hematopoiesis and the leukemia microenvironment.
Cellular & molecular biology letters
Meng Y,Pospiech M,Ali A,Chandwani R,Vergel M,Onyemaechi S,Yaghmour G,Lu R,Alachkar H
48-0032-82 was used in Flow cytometry/Cell sorting to investigate whether targeting CD36 has any detrimental impact on normal hematopoietic cells.
Wed May 24 00:00:00 EDT 2023
Trojan-horse silk fibroin nanocarriers loaded with a re-call antigen to redirect immunity against cancer.
Journal for immunotherapy of cancer
Bari E,Ferrera F,Altosole T,Perteghella S,Mauri P,Rossi R,Passignani G,Mastracci L,Galati M,Astone GI,Mastrogiacomo M,Castagnola P,Fenoglio D,Di Silvestre D,Torre ML,Filaci G
48-0032-82 was used in Flow cytometry/Cell sorting to conclude that both SFNs-OVA and SFNs-CpG induce effective anticancer response through complementary mechanisms and show the efficacy of an innovative active immunotherapy approach based on the redirection of pre-existing immunity against cancer cells.
Sun Jan 01 00:00:00 EST 2023
A cis-element at the Rorc locus regulates the development of type 3 innate lymphoid cells.
Frontiers in immunology
Chang D,Zhang H,Ge J,Xing Q,Guo X,Wang X,Dong C
48-0032-82 was used in Flow cytometry/Cell sorting to identify CNS9 as an essential cis-regulatory element controlling the lineage stability and plasticity of ILC3s through modulating expression levels of RORγt protein.
Tue Mar 28 00:00:00 EDT 2023
The activity of the aryl hydrocarbon receptor in T cells tunes the gut microenvironment to sustain autoimmunity and neuroinflammation.
PLoS biology
Merchak AR,Cahill HJ,Brown LC,Brown RM,Rivet-Noor C,Beiter RM,Slogar ER,Olgun DG,Gaultier A
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Immunohistochemistry
Wed Feb 01 00:00:00 EST 2023
A single-cell atlas reveals the heterogeneity of meningeal immunity in a mouse model of Methyl CpG binding protein 2 deficiency.
Frontiers in immunology
Li H,Hu M,Huang Z,Wang Y,Xu Y,Deng J,Zhu M,Feng W,Xu X
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Immunohistochemistry
Tue Jan 31 00:00:00 EST 2023
LncRNA ANRIL-mediated miR-181b-5p/S1PR1 axis is involved in the progression of uremic cardiomyopathy through activating T cells.
Scientific reports
Xu Y,Cao L,Ji S,Shen W
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Thu Oct 27 00:00:00 EDT 2022
Estrogen Protects against Renal Ischemia-Reperfusion Injury by Regulating Th17/Treg Cell Immune Balance.
Disease markers
Zhang Y,Chang Y,Han Z,Ma K,Zeng X,Li L
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Tue Oct 18 00:00:00 EDT 2022
Therapeutic CFTR Correction Normalizes Systemic and Lung-Specific S1P Level Alterations Associated with Heart Failure.
International journal of molecular sciences
Uhl FE,Vanherle L,Matthes F,Meissner A
48-0032-82 was used in Flow cytometry/Cell sorting to suggest an important role for the CFTR-S1P axis in HF-mediated systemic and pulmonary inflammation.
Fri Jan 14 00:00:00 EST 2022
Loss of phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (Pip5k1c) in mesenchymal stem cells leads to osteopenia by impairing bone remodeling.
The Journal of biological chemistry
Yan Q,Gao H,Yao Q,Ling K,Xiao G
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2022
Maturation and specialization of group 2 innate lymphoid cells through the lung-gut axis.
Nature communications
Zhao M,Shao F,Yu D,Zhang J,Liu Z,Ma J,Xia P,Wang S
48-0032-82 was used in Flow cytometry/Cell sorting to show that ILC2s undergo translocation via the lung-gut axis upon IL-33 treatment.
Fri Dec 09 00:00:00 EST 2022
Foxo3a tempers excessive glutaminolysis in activated T cells to prevent fatal gut inflammation in the murine IL-10-/- model of colitis.
Cell death and differentiation
Hajjar S,Nathan N,Joseph J,Mottawea W,Ariana A,Pyatibrat S,Harper ME,Alain T,Blais A,Russell RC,Sad S
48-0032-82 was used in Flow cytometry/Cell sorting to show that Foxo3a restricts the abundance of colitogenic microbiota in IL-10-deficient mice.
Tue Mar 01 00:00:00 EST 2022
Low-dose IL-2 shapes a tolerogenic gut microbiota that improves autoimmunity and gut inflammation.
JCI insight
Tchitchek N,Nguekap Tchoumba O,Pires G,Dandou S,Campagne J,Churlaud G,Fourcade G,Hoffmann TW,Strozzi F,Gaal C,Bonny C,Le Chatelier E,Erlich SD,Sokol H,Klatzmann D
48-0032-82 was used in Flow cytometry/Cell sorting to provide potentially novel insight for understanding the mode of action of Treg-directed therapies.
Thu Sep 08 00:00:00 EDT 2022
Choroid plexus-selective inactivation of adenosine A2A receptors protects against T cell infiltration and experimental autoimmune encephalomyelitis.
Journal of neuroinflammation
Zheng W,Feng Y,Zeng Z,Ye M,Wang M,Liu X,Tang P,Shang H,Sun X,Lin X,Wang M,Li Z,Weng Y,Guo W,Vakal S,Chen JF
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Fri Feb 18 00:00:00 EST 2022
Selective B cell depletion upon intravenous infusion of replication-incompetent anti-CD19 CAR lentivirus.
Molecular therapy. Methods & clinical development
Rive CM,Yung E,Dreolini L,Brown SD,May CG,Woodsworth DJ,Holt RA
48-0032-82 was used in Flow cytometry/Cell sorting to indicate that direct intravenous infusion of conventional VSV-G-pseudotyped lentiviral particles carrying a CD19 CAR transgene can transduce T cells that then fully ablate endogenous B cells in wild-type mice.
Thu Sep 08 00:00:00 EDT 2022
B cells imprint adoptively transferred CD8+ T cells with enhanced tumor immunity.
Journal for immunotherapy of cancer
Smith AS,Knochelmann HM,Wyatt MM,Rangel Rivera GO,Rivera-Reyes AM,Dwyer CJ,Ware MB,Cole AC,Neskey DM,Rubinstein MP,Liu B,Thaxton JE,Bartee E,Paulos CM
48-0032-82 was used in Flow cytometry/Cell sorting to investigate how tumor-specific murine CD8+ T cells and human tumor infiltrating lymphocytes (TILs) are impacted when expanded ex vivo with the TLR9 agonist CpG.
Sat Jan 01 00:00:00 EST 2022
Increased demand for NAD+ relative to ATP drives aerobic glycolysis.
Molecular cell
Luengo A,Li Z,Gui DY,Sullivan LB,Zagorulya M,Do BT,Ferreira R,Naamati A,Ali A,Lewis CA,Thomas CJ,Spranger S,Matheson NJ,Vander Heiden MG
48-0032-82 was used in Flow Cytometry to examine the metabolic consequence of activating the pyruvate dehydrogenase complex (PDH) to increase pyruvate oxidation at the expense of fermentation.
Thu Feb 18 00:00:00 EST 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
The Journal of experimental medicine
Ho TT,Dellorusso PV,Verovskaya EV,Bakker ST,Flach J,Smith LK,Ventura PB,Lansinger OM,Hérault A,Zhang SY,Kang YA,Mitchell CA,Villeda SA,Passegué E
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Intracellular aggregation of peptide-reprogrammed small molecule nanoassemblies enhances cancer chemotherapy and combinatorial immunotherapy.
Acta pharmaceutica Sinica. B
Peng J,Xiao Y,Yang Q,Liu Q,Chen Y,Shi K,Hao Y,Han R,Qian Z
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Liver X receptor beta deficiency attenuates autoimmune-associated neuroinflammation in a T cell-dependent manner.
Journal of autoimmunity
Bogie JFJ,Vanmierlo T,Vanmol J,Timmermans S,Mailleux J,Nelissen K,Wijnands E,Wouters K,Stinissen P,Gustafsson JÅ,Steffensen KR,Mulder M,Zelcer N,Hendriks JJA
48-0032-82 was used in Flow cytometry/Cell sorting to show that LXRα and LXRβ have an opposite impact on immune cell function and disease severity in the experimental autoimmune encephalomyelitis model, an experimental multiple sclerosis model.
Mon Nov 01 00:00:00 EDT 2021
PD-L1 overexpression conveys tolerance of mesenchymal stem cell-derived cardiomyocyte-like cells in an allogeneic mouse model.
Journal of cellular physiology
Mardomi A,Limoni SK,Rahbarghazi R,Mohammadi N,Khorashadizadeh M,Ranjbaran H,Nataj HH,Jafari N,Hasani B,Abediankenari S
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Immunohistochemistry
Wed Sep 01 00:00:00 EDT 2021
Early inflammation precedes cardiac fibrosis and heart failure in desmoglein 2 murine model of arrhythmogenic cardiomyopathy.
Cell and tissue research
Ng KE,Delaney PJ,Thenet D,Murtough S,Webb CM,Zaman N,Tsisanova E,Mastroianni G,Walker SLM,Westaby JD,Pennington DJ,Pink R,Kelsell DP,Tinker A
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2021
Irradiated whole-cell vaccine suppresses hepatocellular carcinoma growth in mice via Th9 cells.
Oncology letters
Chen J,Ding Y,Huang F,Lan R,Wang Z,Huang W,Chen R,Wu B,Fu L,Yang Y,Liu J,Hong J,Zhang W,Zhang L
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Neuroimmune Consequences of eIF4E Phosphorylation on Chemotherapy-Induced Peripheral Neuropathy.
Frontiers in immunology
Agalave NM,Mody PH,Szabo-Pardi TA,Jeong HS,Burton MD
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Mon Sep 20 00:00:00 EDT 2021
Alphavirus-Driven Interferon Gamma (IFNg) Expression Inhibits Tumor Growth in Orthotopic 4T1 Breast Cancer Model.
Vaccines
Trofimova O,Korotkaja K,Skrastina D,Jansons J,Spunde K,Isaguliants M,Zajakina A
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Wed Oct 27 00:00:00 EDT 2021
Functional inhibition of lactate dehydrogenase suppresses pancreatic adenocarcinoma progression.
Clinical and translational medicine
Cheng CS,Tan HY,Wang N,Chen L,Meng Z,Chen Z,Feng Y
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Immunohistochemistry (Paraffin)
Tue Jun 01 00:00:00 EDT 2021
Functional inhibition of lactate dehydrogenase suppresses pancreatic adenocarcinoma progression.
Clinical and translational medicine
Cheng CS,Tan HY,Wang N,Chen L,Meng Z,Chen Z,Feng Y
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Immunohistochemistry (Paraffin)
Tue Jun 01 00:00:00 EDT 2021
Molecular Mechanisms Underpinning the Circulation and Cellular Uptake of Mycobacterium ulcerans Toxin Mycolactone.
Frontiers in pharmacology
Tello Rubio B,Bugault F,Baudon B,Raynal B,Brûlé S,Morel JD,Saint-Auret S,Blanchard N,Demangel C,Guenin-Macé L
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Tue Oct 05 00:00:00 EDT 2021
Expression of CCRL2 Inhibits Tumor Growth by Concentrating Chemerin and Inhibiting Neoangiogenesis.
Cancers
Al Delbany D,Robert V,Dubois-Vedrenne I,Del Prete A,Vernimmen M,Radi A,Lefort A,Libert F,Wittamer V,Sozzani S,Parmentier M
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Immunohistochemistry
Tue Oct 05 00:00:00 EDT 2021
Small Molecule Potentiator of Adjuvant Activity Enhancing Survival to Influenza Viral Challenge.
Frontiers in immunology
Saito T,Sako Y,Sato-Kaneko F,Hosoya T,Yao S,Lao FS,Shpigelman J,Messer K,Pu M,Shukla NM,Chan M,Chu PJ,Cottam HB,Hayashi T,Carson DA,Corr M
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Fri Dec 10 00:00:00 EST 2021
Gut Microbiota Dysbiosis Induced by Intracerebral Hemorrhage Aggravates Neuroinflammation in Mice.
Frontiers in microbiology
Yu X,Zhou G,Shao B,Zhou H,Xu C,Yan F,Wang L,Chen G,Li J,Fu X
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Wed May 26 00:00:00 EDT 2021
Type 1 Cytotoxic T Cells Increase in Placenta after Intrauterine Inflammation.
Frontiers in immunology
Liu J,Liu Y,Panda S,Liu A,Lei J,Burd I
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Fri Dec 17 00:00:00 EST 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
A mouse model for the study of anti-tumor T cell responses in Kras-driven lung adenocarcinoma.
Cell reports methods
Fitzgerald B,Connolly KA,Cui C,Fagerberg E,Mariuzza DL,Hornick NI,Foster GG,William I,Cheung JF,Joshi NS
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Immunocytochemistry
Mon Sep 27 00:00:00 EDT 2021
Inducible T-Cell Costimulator Mediates Lymphocyte/Macrophage Interactions During Liver Repair.
Frontiers in immunology
Ramavath NN,Gadipudi LL,Provera A,Gigliotti LC,Boggio E,Bozzola C,Albano E,Dianzani U,Sutti S
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Mon Feb 14 00:00:00 EST 2022
Assessing Lupus-Like Disease in Murine Model Systems.
Current protocols
Lee HY,Celhar T,Fairhurst AM
48-0032-82 was used in Flow Cytometry to evaluate the underlying immunological features of the disease, as a more sensitive strategy to understand the disease itself and the mechanisms of potential novel therapeutics.
Mon Nov 01 00:00:00 EDT 2021
Plasma cell dynamics in the bone marrow niche.
Cell reports
Benet Z,Jing Z,Fooksman DR
48-0032-82 was used in flow cytometry to suggest that changes in PC motility and CXCR4 expression are linked with survival of long-lived PCs in the bone marrow (BM).
Tue Feb 09 00:00:00 EST 2021
CD169+ Subcapsular Macrophage Role in Antigen Adjuvant Activity.
Frontiers in immunology
Lisk C,Yuen R,Kuniholm J,Antos D,Reiser ML,Wetzler LM
48-0032-82 was used in Flow cytometry/Cell sorting to investigate the role of subcapsular CD169+ marginal zone macrophages in antibody production.
Tue Sep 14 00:00:00 EDT 2021
Soft implantable drug delivery device integrated wirelessly with wearable devices to treat fatal seizures.
Science advances
Joo H,Lee Y,Kim J,Yoo JS,Yoo S,Kim S,Arya AK,Kim S,Choi SH,Lu N,Lee HS,Kim S,Lee ST,Kim DH
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Immunohistochemistry
Fri Jan 01 00:00:00 EST 2021
Investigating the Mechanism of Trimethoprim-Induced Skin Rash and Liver Injury.
Toxicological sciences : an official journal of the Society of Toxicology
Cao Y,Bairam A,Jee A,Liu M,Uetrecht J
48-0032-82 was used in Flow cytometry/Cell sorting to provide important data required to understand the mechanism of TMP-induced skin rash and drug-induced skin rash in general.
Fri Feb 26 00:00:00 EST 2021
MAFG-driven astrocytes promote CNS inflammation.
Nature
Wheeler MA,Clark IC,Tjon EC,Li Z,Zandee SEJ,Couturier CP,Watson BR,Scalisi G,Alkwai S,Rothhammer V,Rotem A,Heyman JA,Thaploo S,Sanmarco LM,Ragoussis J,Weitz DA,Petrecca K,Moffitt JR,Becher B,Antel JP,Prat A,Quintana FJ
48-0032-82 was used in Flow Cytometry to identify candidate therapeutic targets in multiple sclerosis.
Sat Feb 01 00:00:00 EST 2020
Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells.
The Journal of clinical investigation
Khiew SH,Jain D,Chen J,Yang J,Yin D,Young JS,Dent A,Sciammas R,Alegre ML,Chong AS
48-0032 was used in Flow cytometry/Cell sorting to showed that alloreactive B cells were not deleted but rapidly lost their ability to differentiate into germinal center B cells and secrete donor-specific antibodies., by using a murine model of heart tolerance.
Wed Jul 01 00:00:00 EDT 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
Herpes Simplex Virus 1-Specific CD8+ T Cell Priming and Latent Ganglionic Retention Are Shaped by Viral Epitope Promoter Kinetics.
Journal of virology
Treat BR,Bidula SM,St Leger AJ,Hendricks RL,Kinchington PR
48-0032 was used in Flow cytometry/Cell sorting to address how expression by HSV-1 influences the formation and ganglionic retention of CD8+ T cell populations.
Fri Feb 14 00:00:00 EST 2020
Novel enhanced GFP-positive congenic inbred strain establishment and application of tumor-bearing nude mouse model.
Cancer science
Lan Q,Chen Y,Dai C,Li S,Fei X,Dong J,Shen Y,Dai X,Lu Z,Liu B,Wang Q,Wang H,Zhou Z,Ji X,Wang Z,Huang Q
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
In Situ Therapeutic Cancer Vaccination with an Oncolytic Virus Expressing Membrane-Tethered IL-2.
Molecular therapy oncolytics
Liu W,Dai E,Liu Z,Ma C,Guo ZS,Bartlett DL
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Fri Jun 26 00:00:00 EDT 2020
Loss of mural cell-derived laminin aggravates hemorrhagic brain injury.
Journal of neuroinflammation
Gautam J,Xu L,Nirwane A,Nguyen B,Yao Y
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Immunohistochemistry
Mon Apr 06 00:00:00 EDT 2020
Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.
JCI insight
Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Thu Aug 20 00:00:00 EDT 2020
Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma.
Nature communications
Galvani E,Mundra PA,Valpione S,Garcia-Martinez P,Smith M,Greenall J,Thakur R,Helmink B,Andrews MC,Boon L,Chester C,Gremel G,Hogan K,Mandal A,Zeng K,Banyard A,Ashton G,Cook M,Lorigan P,Wargo JA,Dhomen N,Marais R
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Immunohistochemistry (Frozen)
Wed Feb 12 00:00:00 EST 2020
Triptolide Attenuates Transplant Vasculopathy Through Multiple Pathways.
Frontiers in immunology
Luo Z,Liao T,Zhang Y,Zheng H,Sun Q,Han F,Yang Z,Sun Q
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Thu Mar 25 00:00:00 EDT 2021
C5aR1 Activation Drives Early IFN-γ Production to Control Experimental Toxoplasma gondii Infection.
Frontiers in immunology
Briukhovetska D,Ohm B,Mey FT,Aliberti J,Kleingarn M,Huber-Lang M,Karsten CM,Köhl J
48-0032 was used in Flow cytometry/Cell sorting to suggest a model in which the C5a/C5aR1 axis promotes IFN-γ production from NK cells as a mechanism to control acute Toxoplasma gondii infection.
Mon Apr 05 00:00:00 EDT 2021
Pharmacological depletion of microglia and perivascular macrophages prevents Vascular Cognitive Impairment in Ang II-induced hypertension.
Theranostics
Kerkhofs D,van Hagen BT,Milanova IV,Schell KJ,van Essen H,Wijnands E,Goossens P,Blankesteijn WM,Unger T,Prickaerts J,Biessen EA,van Oostenbrugge RJ,Foulquier S
48-0032 was used in Flow cytometry/Cell sorting to support the critical role of brain immune cells in the pathogenesis of hypertension-related cognitive impairment.
Tue Jun 01 00:00:00 EDT 2021
Toll-Like Receptor Ligand Based Adjuvant, PorB, Increases Antigen Deposition on Germinal Center Follicular Dendritic Cells While Enhancing the Follicular Dendritic Cells Network.
Frontiers in immunology
Lisk C,Yuen R,Kuniholm J,Antos D,Reiser ML,Wetzler LM
48-0032 was used in Flow cytometry/Cell sorting to investigate cellular mechanisms of adjuvanticity, focusing on the fate of intact antigen in the germinal center and association with follicular dendritic cells (FDCs).
Mon Apr 05 00:00:00 EDT 2021
Developmental Dysfunction of the Central Nervous System Lymphatics Modulates the Adaptive Neuro-Immune Response in the Perilesional Cortex in a Mouse Model of Traumatic Brain Injury.
Frontiers in immunology
Wojciechowski S,Virenque A,Vihma M,Galbardi B,Rooney EJ,Keuters MH,Antila S,Koistinaho J,Noe FM
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Immunohistochemistry (Frozen)
Wed May 19 00:00:00 EDT 2021
Small Molecule Enhancers of Endosome-to-Cytosol Import Augment Anti-tumor Immunity.
Cell reports
Kozik P,Gros M,Itzhak DN,Joannas L,Heurtebise-Chrétien S,Krawczyk PA,Rodríguez-Silvestre P,Alloatti A,Magalhaes JG,Del Nery E,Borner GHH,Amigorena S
48-0032 was used in Flow cytometry/Cell sorting to identify 37 enhancers of antigen import from endolysosomes into the cytosol from screening 700 US Food and Drug Administration (FDA)-approved drugs and reveal their mechanism of action.
Tue Jul 14 00:00:00 EDT 2020
Human and Mouse Transcriptome Profiling Identifies Cross-Species Homology in Pulmonary and Lymph Node Mononuclear Phagocytes.
Cell reports
Leach SM,Gibbings SL,Tewari AD,Atif SM,Vestal B,Danhorn T,Janssen WJ,Wager TD,Jakubzick CV
48-0032 was used in Flow cytometry/Cell sorting to created a gene expression compendium across 24 distinct human and murine lung and lymph node mononuclear phagocyte (MP), along with human blood and murine spleen MPs, to serve as validation datasets.
Tue Nov 03 00:00:00 EST 2020
Inflammation-Induced Lactate Leads to Rapid Loss of Hepatic Tissue-Resident NK Cells.
Cell reports
Dodard G,Tata A,Erick TK,Jaime D,Miah SMS,Quatrini L,Escalière B,Ugolini S,Vivier E,Brossay L
48-0032 was used in Flow cytometry/Cell sorting to characterize the kinetics and immune response of each of the hepatic NK cell populations to viral challenge and other stimuli.
Tue Jul 07 00:00:00 EDT 2020
CD8+ T cells promote cytokine responses to stress.
Cytokine
Clark SM,Song C,Li X,Keegan AD,Tonelli LH
48-0032-82 was used in Flow Cytometry to assess the role of T cells on cytokine levels after exposure to stress in the learned helplessness paradigm.
Tue Jan 01 00:00:00 EST 2019
Evaluation of serum biomarkers and efficacy of MTX in women with ectopic pregnancy.
Molecular medicine reports
Li H,Liu Y,Wen S,Jia H,Du Y
48-0032-82 was used in Flow cytometry/Cell sorting to identify and determine the efficacy of serum biomarkers for the prompt diagnosis of ectopic pregnancy.
Sun Sep 01 00:00:00 EDT 2019
Deletion of C-C Motif Chemokine Ligand 5 Worsens Invariant Natural Killer T-Cell-Mediated Hepatitis via Compensatory Up-regulation of CXCR2-Related Chemokine Activity.
Cellular and molecular gastroenterology and hepatology
Chen L,Gu J,Qian Y,Li M,Qian Y,Xu M,Li J,Wen Y,Xia L,Li J,Xia Q,Kong X,Wu H
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Tue Jun 04 00:00:00 EDT 2019
Blood autophagy defect causes accelerated non-hematopoietic organ aging.
Aging
Fang Y,Zhu L,An N,Jiang G,Qian J,Zhao R,Yuan N,Zhang S,Wang J
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Sun Jul 21 00:00:00 EDT 2019
MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.
Journal for immunotherapy of cancer
Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Thu Nov 28 00:00:00 EST 2019
LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy.
Nature communications
Pascual-García M,Bonfill-Teixidor E,Planas-Rigol E,Rubio-Perez C,Iurlaro R,Arias A,Cuartas I,Sala-Hojman A,Escudero L,Martínez-Ricarte F,Huber-Ruano I,Nuciforo P,Pedrosa L,Marques C,Braña I,Garralda E,Vieito M,Squatrito M,Pineda E,Graus F,Espejo C,Sahuquillo J,Tabernero J,Seoane J
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Tue Jun 11 00:00:00 EDT 2019
MALT1 Proteolytic Activity Suppresses Autoimmunity in a T Cell Intrinsic Manner.
Frontiers in immunology
Demeyer A,Skordos I,Driege Y,Kreike M,Hochepied T,Baens M,Staal J,Beyaert R
48-0032 was used in Flow cytometry/Cell sorting to establish that suppression of autoimmune responses is due to the T-cell intrinsic role of MALT1 proteolytic activity.
Mon Oct 05 00:00:00 EDT 2020
Persistence of Integrase-Deficient Lentiviral Vectors Correlates with the Induction of STING-Independent CD8+ T Cell Responses.
Cell reports
Cousin C,Oberkampf M,Felix T,Rosenbaum P,Weil R,Fabrega S,Morante V,Negri D,Cara A,Dadaglio G,Leclerc C
48-0032 was used in Flow cytometry/Cell sorting to demonstrate that integrase-deficient lentiviral vectors can trigger persistent adaptive response by the mediation of a weak and transient innate response alongside the persistence of the vector in tissues.
Tue Jan 29 00:00:00 EST 2019
Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy.
Cell reports
Hirukawa A,Singh S,Wang J,Rennhack JP,Swiatnicki M,Sanguin-Gendreau V,Zuo D,Daldoul K,Lavoie C,Park M,Andrechek ER,Westbrook TF,Harris LN,Varadan V,Smith HW,Muller WJ
48-0032-82 was used in Flow cytometry/Cell sorting to provide evidence that EZH2 inhibitors promote interferon-driven immune responses that enhance the efficacy of anti-ErbB2 mAbs, suggesting the potential clinical benefit of epigenomic reprogramming by H3K27me3 depletion in Trastuzumab-resistant disease.
Tue Oct 08 00:00:00 EDT 2019
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
Commensals Suppress Intestinal Epithelial Cell Retinoic Acid Synthesis to Regulate Interleukin-22 Activity and Prevent Microbial Dysbiosis.
Immunity
Grizotte-Lake M,Zhong G,Duncan K,Kirkwood J,Iyer N,Smolenski I,Isoherranen N,Vaishnava S
48-0032 was used in Flow cytometry/Cell sorting to define a regulatory circuit wherein bacterial regulation of IEC-intrinsic RA synthesis protects microbial communities in the gut from excessive immune activity, achieving a balance that prevents colonization by enteric pathogens.
Tue Dec 18 00:00:00 EST 2018
Cbl Ubiquitin Ligases Control B Cell Exit from the Germinal-Center Reaction.
Immunity
Li X,Gadzinsky A,Gong L,Tong H,Calderon V,Li Y,Kitamura D,Klein U,Langdon WY,Hou F,Zou YR,Gu H
48-0032-82 was used in Flow Cytometry to show that deleting E3 ubiquitin ligases Cbl and Cbl-b (Cbls) in GC B cells results in the early exit of high-affinity antigen-specific B cells from the GC reaction and thus impaired clonal expansion.
Tue Mar 20 00:00:00 EDT 2018
PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy.
Cell stem cell
Hsu JI,Dayaram T,Tovy A,De Braekeleer E,Jeong M,Wang F,Zhang J,Heffernan TP,Gera S,Kovacs JJ,Marszalek JR,Bristow C,Yan Y,Garcia-Manero G,Kantarjian H,Vassiliou G,Futreal PA,Donehower LA,Takahashi K,Goodell MA
48-0032 was used in Flow cytometry/Cell sorting to establish the clinical relevance of PPM1D mutations in clonal haematopoiesis and the importance of studying mutation-treatment interactions.
Thu Nov 01 00:00:00 EDT 2018
Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival.
The Journal of clinical investigation
Bahmani B,Uehara M,Jiang L,Ordikhani F,Banouni N,Ichimura T,Solhjou Z,Furtmüller GJ,Brandacher G,Alvarez D,von Andrian UH,Uchimura K,Xu Q,Vohra I,Yilmam OA,Haik Y,Azzi J,Kasinath V,Bromberg JS,McGrath MM,Abdi R
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Immunofluorescence
Thu Nov 01 00:00:00 EDT 2018
Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival.
The Journal of clinical investigation
Bahmani B,Uehara M,Jiang L,Ordikhani F,Banouni N,Ichimura T,Solhjou Z,Furtmüller GJ,Brandacher G,Alvarez D,von Andrian UH,Uchimura K,Xu Q,Vohra I,Yilmam OA,Haik Y,Azzi J,Kasinath V,Bromberg JS,McGrath MM,Abdi R
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Immunofluorescence
Thu Nov 01 00:00:00 EDT 2018
In Vitro Priming of Adoptively Transferred T Cells with a RORγ Agonist Confers Durable Memory and Stemness In Vivo.
Cancer research
Hu X,Majchrzak K,Liu X,Wyatt MM,Spooner CJ,Moisan J,Zou W,Carter LL,Paulos CM
48-0032 was used in Flow cytometry/Cell sorting to demonstrate that addition of a synthetic, small-molecule RORγ agonist during ex vivo expansion potentiates the anti-tumour activity of human Th17 and Tc17 cells redirected with a chimeric antigen receptor.
Sun Jul 15 00:00:00 EDT 2018
De Novo Fatty Acid Synthesis During Mycobacterial Infection Is a Prerequisite for the Function of Highly Proliferative T Cells, But Not for Dendritic Cells or Macrophages.
Frontiers in immunology
Stüve P,Minarrieta L,Erdmann H,Arnold-Schrauf C,Swallow M,Guderian M,Krull F,Hölscher A,Ghorbani P,Behrends J,Abraham WR,Hölscher C,Sparwasser TD,Berod L
48-0032-82 was used in Flow Cytometry to reveal that acetyl-CoA carboxylase 1-dependent fatty acid synthesis is a crucial mechanism in T cells, but not dendritic cells or macrophages, to fight against mycobacterial infection.
Wed Apr 10 00:00:00 EDT 2019
Impact of hyperglycemia on autoimmune pancreatitis and regulatory T-cells.
World journal of gastroenterology
Müller-Graff FT,Fitzner B,Jaster R,Vollmar B,Zechner D
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Sat Jul 28 00:00:00 EDT 2018
Neonatal adoptive transfer of lymphocytes rescues social behaviour during adolescence in immune-deficient mice.
The European journal of neuroscience
Clark SM,Vaughn CN,Soroka JA,Li X,Tonelli LH
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
CD4+ T cells are activated in regional lymph nodes and migrate to skin to initiate lymphedema.
Nature communications
García Nores GD,Ly CL,Cuzzone DA,Kataru RP,Hespe GE,Torrisi JS,Huang JJ,Gardenier JC,Savetsky IL,Nitti MD,Yu JZ,Rehal S,Mehrara BJ
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Thu May 17 00:00:00 EDT 2018
Microglia prevent peripheral immune cell invasion and promote an anti-inflammatory environment in the brain of APP-PS1 transgenic mice.
Journal of neuroinflammation
Unger MS,Schernthaner P,Marschallinger J,Mrowetz H,Aigner L
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Fri Sep 21 00:00:00 EDT 2018
Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice.
mSphere
Quach D,Collins F,Parameswaran N,McCabe L,Britton RA
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Tue Dec 11 00:00:00 EST 2018
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Tue Dec 11 00:00:00 EST 2018
STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia.
Cell reports
Saint Fleur-Lominy S,Maus M,Vaeth M,Lange I,Zee I,Suh D,Liu C,Wu X,Tikhonova A,Aifantis I,Feske S
48-0032 was used in Flow cytometry/Cell sorting to investigate the role of store-operated Ca2+ entry mediated by ORAI1, and STIM1 and STIM2 in T-cell acute lymphoblastic leukaemia.
Tue Sep 11 00:00:00 EDT 2018
A Gut Commensal-Produced Metabolite Mediates Colonization Resistance to Salmonella Infection.
Cell host & microbe
Jacobson A,Lam L,Rajendram M,Tamburini F,Honeycutt J,Pham T,Van Treuren W,Pruss K,Stabler SR,Lugo K,Bouley DM,Vilches-Moure JG,Smith M,Sonnenburg JL,Bhatt AS,Huang KC,Monack D
48-0032-82 was used in flow cytometry to provide mechanistic understanding into the role of individualized microbial communities in host-to-host variability of pathogen transmission.
Wed Aug 08 00:00:00 EDT 2018
Direct conversion of injury-site myeloid cells to fibroblast-like cells of granulation tissue.
Nature communications
Sinha M,Sen CK,Singh K,Das A,Ghatak S,Rhea B,Blackstone B,Powell HM,Khanna S,Roy S
48-0032 was used in Flow cytometry/Cell sorting to introduce a paradigm wherein myeloid cells are recognized as a major source of fibroblast-like cells in granulation tissue.
Mon Mar 05 00:00:00 EST 2018
Characterization of the Inflammatory Response in Dystrophic Muscle Using Flow Cytometry.
Methods in molecular biology (Clifton, N.J.)
Kastenschmidt JM,Avetyan I,Villalta SA
48-0032 was used in Flow cytometry/Cell sorting to highlight methods for the isolation and study of immune cell populations from muscles of mouse models of DMD.
Tue Jun 05 00:00:00 EDT 2018
Renal Sodium Gradient Orchestrates a Dynamic Antibacterial Defense Zone.
Cell
Berry MR,Mathews RJ,Ferdinand JR,Jing C,Loudon KW,Wlodek E,Dennison TW,Kuper C,Neuhofer W,Clatworthy MR
48-0032-82 was used in Flow Cytometry to reveal a critical accessory role for the homeostatic function of a vital organ in optimizing tissue defense.
Thu Aug 24 00:00:00 EDT 2017
Sphingosine-1-Phosphate Prevents Egress of Hematopoietic Stem Cells From Liver to Reduce Fibrosis.
Gastroenterology
King A,Houlihan DD,Kavanagh D,Haldar D,Luu N,Owen A,Suresh S,Than NN,Reynolds G,Penny J,Sumption H,Ramachandran P,Henderson NC,Kalia N,Frampton J,Adams DH,Newsome PN
48-0032 was used in Flow cytometry/Cell sorting to investigate the role of sphingosine-1-phosphate in the response of hematopoietic stem cells to liver fibrosis in mice.
Sat Jul 01 00:00:00 EDT 2017
Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target.
Cell stem cell
Schneider RK,Mullally A,Dugourd A,Peisker F,Hoogenboezem R,Van Strien PMH,Bindels EM,Heckl D,Büsche G,Fleck D,Müller-Newen G,Wongboonsin J,Ventura Ferreira M,Puelles VG,Saez-Rodriguez J,Ebert BL,Humphreys BD,Kramann R
48-0032 was used in Flow cytometry/Cell sorting to study the cellular origin of bone marrow fibrosis.
Thu Jun 01 00:00:00 EDT 2017
T-Cell Mineralocorticoid Receptor Controls Blood Pressure by Regulating Interferon-Gamma.
Circulation research
Sun XN,Li C,Liu Y,Du LJ,Zeng MR,Zheng XJ,Zhang WC,Liu Y,Zhu M,Kong D,Zhou L,Lu L,Shen ZX,Yi Y,Du L,Qin M,Liu X,Hua Z,Sun S,Yin H,Zhou B,Yu Y,Zhang Z,Duan SZ
48-0032 was used in Flow cytometry/Cell sorting to determine the role of T-cell mineralocorticoid receptor in blood pressure regulation and explore the mechanism.
Fri May 12 00:00:00 EDT 2017
Characterization of meningeal type 2 innate lymphocytes and their response to CNS injury.
The Journal of experimental medicine
Gadani SP,Smirnov I,Wiltbank AT,Overall CC,Kipnis J
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Immunofluorescence
Wed Feb 01 00:00:00 EST 2017
Critical role for Sec22b-dependent antigen cross-presentation in antitumor immunity.
The Journal of experimental medicine
Alloatti A,Rookhuizen DC,Joannas L,Carpier JM,Iborra S,Magalhaes JG,Yatim N,Kozik P,Sancho D,Albert ML,Amigorena S
48-0032 was used in Flow cytometry/Cell sorting to determine that Sec22b-dependent cross-presentation in dendritic cells is required to initiate CD8 T cell responses to dead cells, and induce effective anti-tumour immune responses during anti-PD-1 treatment.
Mon Aug 07 00:00:00 EDT 2017
ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control.
The Journal of experimental medicine
Schwartz C,Khan AR,Floudas A,Saunders SP,Hams E,Rodewald HR,McKenzie ANJ,Fallon PG
48-0032 was used in Flow cytometry/Cell sorting to study how group 2 innate lymphoid cells regulate adaptive Th2 cell functions.
Mon Sep 04 00:00:00 EDT 2017
Diet-induced obesity causes visceral, but not subcutaneous, lymph node hyperplasia via increases in specific immune cell populations.
Cell proliferation
Magnuson AM,Regan DP,Fouts JK,Booth AD,Dow SW,Foster MT
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Immunocytochemistry
Sun Oct 01 00:00:00 EDT 2017
Semaphorin 3E Deficiency Exacerbates Airway Inflammation, Hyperresponsiveness, and Remodeling in a Mouse Model of Allergic Asthma.
Journal of immunology (Baltimore, Md. : 1950)
Movassagh H,Shan L,Mohammed A,Halayko AJ,Gounni AS
48-0032 was used in Flow cytometry/Cell sorting to identify Semaphorin 3E as a novel regulatory molecule in allergic asthma that acts upstream of proallergic events.
Wed Mar 01 00:00:00 EST 2017
Autophagy in Dendritic Cells and B Cells Is Critical for the Inflammatory State of TLR7-Mediated Autoimmunity.
Journal of immunology (Baltimore, Md. : 1950)
Weindel CG,Richey LJ,Mehta AJ,Shah M,Huber BT
48-0032 was used in Flow cytometry/Cell sorting to identify that autophagy in B cells and dendritic cells are key to TLR7-mediated autoimmune disorders.
Wed Feb 01 00:00:00 EST 2017
Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-κB signaling and NLRP3 activation.
International journal of molecular medicine
Zhang B,Wang B,Cao S,Wang Y,Wu D
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
Effect of Early-life Gut Mucosal Compromise on Disease Progression in NOD Mice.
Comparative medicine
Bendtsen KM,Hansen CH,Krych L,Buschard K,Farlov H,Hansen AK
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells.
Oncotarget
Guo XL,Chu L,Ke F,Mu LL,Li Z,Cai JJ,Li HF,Hong DL
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Tue Dec 12 00:00:00 EST 2017
Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells.
eLife
Lee P,Gund R,Dutta A,Pincha N,Rana I,Ghosh S,Witherden D,Kandyba E,MacLeod A,Kobielak K,Havran WL,Jamora C
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in T-Cell Activation
Mon Dec 04 00:00:00 EST 2017
Loss of epidermal AP1 transcription factor function reduces filaggrin level, alters chemokine expression and produces an ichthyosis-related phenotype.
Cell death & disease
Young CA,Rorke EA,Adhikary G,Xu W,Eckert RL
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
Tristetraprolin inhibits macrophage IL-27-induced activation of antitumour cytotoxic T cell responses.
Nature communications
Wang Q,Ning H,Peng H,Wei L,Hou R,Hoft DF,Liu J
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Wed Oct 11 00:00:00 EDT 2017
Rottlerin as a therapeutic approach in psoriasis: Evidence from in vitro and in vivo studies.
PloS one
Min M,Yan BX,Wang P,Landeck L,Chen JQ,Li W,Cai SQ,Zheng M,Man XY
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Tue Jan 16 00:00:00 EST 2018
Th17 cells are refractory to senescence and retain robust antitumor activity after long-term ex vivo expansion.
JCI insight
Bowers JS,Nelson MH,Majchrzak K,Bailey SR,Rohrer B,Kaiser AD,Atkinson C,Gattinoni L,Paulos CM
48-0032 was used in Flow cytometry/Cell sorting to study the use of tumour-reactive Th17 cells as a cell therapy for cancer.
Thu Mar 09 00:00:00 EST 2017
Regulatory T cells and IL10 suppress pulmonary host defense during early-life exposure to radical containing combustion derived ultrafine particulate matter.
Respiratory research
Jaligama S,Saravia J,You D,Yadav N,Lee GI,Shrestha B,Cormier SA
48-0032 was used in Flow cytometry/Cell sorting to show that murine neonate exposure to environmentally persistent free radicals induces regulatory T Cells and IL10 resulting in suppressed adaptive T cell responses and increased severity of influenza.
Fri Jan 13 00:00:00 EST 2017
Downregulation of semaphorin 3E promotes hallmarks of experimental chronic allergic asthma.
Oncotarget
Movassagh H,Shan L,Duke-Cohan JS,Chakir J,Halayko AJ,Koussih L,Gounni AS
48-0032 was used in Flow cytometry/Cell sorting to determine the role of semaphorin 3E in the chronic course of allergic asthma.
Fri Nov 17 00:00:00 EST 2017
The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome.
Cell
Gury-BenAri M,Thaiss CA,Serafini N,Winter DR,Giladi A,Lara-Astiaso D,Levy M,Salame TM,Weiner A,David E,Shapiro H,Dori-Bachash M,Pevsner-Fischer M,Lorenzo-Vivas E,Keren-Shaul H,Paul F,Harmelin A,Eberl G,Itzkovitz S,Tanay A,Di Santo JP,Elinav E,Amit I
48-0032 was used in Flow cytometry/Cell sorting to investigate the cellular states and regulatory landscapes of innate lymphoid cells.
Thu Aug 25 00:00:00 EDT 2016
Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq.
Cell
Jaitin DA,Weiner A,Yofe I,Lara-Astiaso D,Keren-Shaul H,David E,Salame TM,Tanay A,van Oudenaarden A,Amit I
48-0032 was used in Flow cytometry/Cell sorting to establish CRISP-seq as a broadly applicable, comprehensive, and unbiased approach for elucidating mammalian regulatory circuits.
Thu Dec 15 00:00:00 EST 2016
Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission.
Immunity
Tian Y,Kuo CF,Akbari O,Ou JH
48-0032 was used in Flow cytometry/Cell sorting to show in mice, that maternal hepatitis B virus (HBV) impairs CD8(+) T cell responses to HBV in her offspring, resulting in HBV persistence.
Tue May 17 00:00:00 EDT 2016
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Lymphatic vessels regulate immune microenvironments in human and murine melanoma.
The Journal of clinical investigation
Lund AW,Wagner M,Fankhauser M,Steinskog ES,Broggi MA,Spranger S,Gajewski TF,Alitalo K,Eikesdal HP,Wiig H,Swartz MA
48-0032 was used in Flow cytometry/Cell sorting to suggest that the establishment of tumour-associated inflammation and immunity critically depends on lymphatic vessel remodelling and drainage.
Thu Sep 01 00:00:00 EDT 2016
Expansion of brain T cells in homeostatic conditions in lymphopenic Rag2(-/-) mice.
Brain, behavior, and immunity
Song C,Nicholson JD,Clark SM,Li X,Keegan AD,Tonelli LH
48-0032 was used in Flow cytometry/Cell sorting to study the temporal and anatomical expansion of T cells in the Rag2(-/-) mouse model brain under homeostatic conditions.
Sat Oct 01 00:00:00 EDT 2016
IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization.
The Journal of experimental medicine
Yoon J,Leyva-Castillo JM,Wang G,Galand C,Oyoshi MK,Kumar L,Hoff S,He R,Chervonsky A,Oppenheim JJ,Kuchroo VK,van den Brink MR,Malefyt Rde W,Tessier PA,Fuhlbrigge R,Rosenstiel P,Terhorst C,Murphy G,Geha RS
48-0032 was used in Flow cytometry/Cell sorting to elucidate the mechanisms behind DC-derived IL-23 in a model of skin inflammation.
Mon Sep 19 00:00:00 EDT 2016
Development of Th17-Associated Interstitial Kidney Inflammation in Lupus-Prone Mice Lacking the Gene Encoding STAT-1.
Arthritis & rheumatology (Hoboken, N.J.)
Yiu G,Rasmussen TK,Ajami B,Haddon DJ,Chu AD,Tangsombatvisit S,Haynes WA,Diep V,Steinman L,Faix J,Utz PJ
48-0032 was used in Flow cytometry/Cell sorting to investigate the roles of the type I and type II IFN signaling components in systemic Lupus Erythematosus, showing the development of Th17-associated interstitial kidney inflammation in mice lacking STAT-1.
Sun May 01 00:00:00 EDT 2016
Laminin regulates PDGFRβ(+) cell stemness and muscle development.
Nature communications
Yao Y,Norris EH,Mason CE,Strickland S
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Immunofluorescence
Tue May 03 00:00:00 EDT 2016
CD8(+) T-cell Immune Evasion Enables Oncolytic Virus Immunotherapy.
EBioMedicine
Pourchet A,Fuhrmann SR,Pilones KA,Demaria S,Frey AB,Mulvey M,Mohr I
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Nature communications
Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Wed Sep 07 00:00:00 EDT 2016
TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection.
Cell reports
Schleicher U,Paduch K,Debus A,Obermeyer S,König T,Kling JC,Ribechini E,Dudziak D,Mougiakakos D,Murray PJ,Ostuni R,Körner H,Bogdan C
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Tue May 03 00:00:00 EDT 2016
Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.
Scientific reports
Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Wed Jun 15 00:00:00 EDT 2016
Evaluation of Cross-presentation in Bone Marrow-derived Dendritic Cells in vitro and Splenic Dendritic Cells ex vivo Using Antigen-coated Beads.
Bio-protocol
Alloatti A,Kotsias F,Hoffmann E,Amigorena S
48-0032 was used in Flow cytometry/Cell sorting to develop a protocol for evaluating antigen cross-presentation by dendritic cells, both in vivo and ex vivo.
Sun Nov 20 00:00:00 EST 2016
Lymphocyte Isolation, Th17 Cell Differentiation, Activation, and Staining.
Bio-protocol
Kumar P,Kolls JK
48-0032 was used in Flow cytometry/Cell sorting to describe the tools, reagents and procdedure for a Th17 cell differentiation method.
Mon Dec 05 00:00:00 EST 2016
The stress kinase GCN2 does not mediate suppression of antitumor T cell responses by tryptophan catabolism in experimental melanomas.
Oncoimmunology
Sonner JK,Deumelandt K,Ott M,Thomé CM,Rauschenbach KJ,Schulz S,Munteanu B,Mohapatra S,Adam I,Hofer AC,Feuerer M,Opitz CA,Hopf C,Wick W,Platten M
48-0032 was used in Flow cytometry/Cell sorting to investigate whether GCN2 attenuates tumour rejection in experimental B16 melanoma using T cell-specific Gcn2-KO mice.
Tue Jan 12 00:00:00 EST 2021
Perivascular Mast Cells Govern Shear Stress-Induced Arteriogenesis by Orchestrating Leukocyte Function.
Cell reports
Chillo O,Kleinert EC,Lautz T,Lasch M,Pagel JI,Heun Y,Troidl K,Fischer S,Caballero-Martinez A,Mauer A,Kurz ARM,Assmann G,Rehberg M,Kanse SM,Nieswandt B,Walzog B,Reichel CA,Mannell H,Preissner KT,Deindl E
48-0032 was used in Flow cytometry/Cell sorting to find that perivascular mast cells are central regulators of shear stress-induced arteriogenesis by orchestrating leukocyte function and growth factor/cytokine release.
Tue Aug 23 00:00:00 EDT 2016
A role for multiple chimeric antigen receptor-expressing leukocytes in antigen-specific responses to cancer.
Oncotarget
Yong CS,John LB,Devaud C,Prince MH,Johnstone RW,Trapani JA,Darcy PK,Kershaw MH
48-0032 was used in Flow cytometry/Cell sorting to characterise the function of leukocytes from transgenic mice expressing a chimeric antigen receptor under the control of vav, and determine the ability of these mice to respond to ERB-expressing tumours.
Tue Jun 07 00:00:00 EDT 2016
Timing of CSF-1/CSF-1R signaling blockade is critical to improving responses to CTLA-4 based immunotherapy.
Oncoimmunology
Holmgaard RB,Brachfeld A,Gasmi B,Jones DR,Mattar M,Doman T,Murphy M,Schaer D,Wolchok JD,Merghoub T
Fri Jul 01 00:00:00 EDT 2016
Batf3 maintains autoactivation of Irf8 for commitment of a CD8α(+) conventional DC clonogenic progenitor.
Nature immunology
Grajales-Reyes GE,Iwata A,Albring J,Wu X,Tussiwand R,Kc W,Kretzer NM,Briseño CG,Durai V,Bagadia P,Haldar M,Schönheit J,Rosenbauer F,Murphy TL,Murphy KM
48-0032 was used in Flow cytometry/Cell sorting to investigate the role of the transcription factors Batf3 and IRF8 in the development of CD8α(+) conventional dendritic cells (cDCs)..
Wed Jul 01 00:00:00 EDT 2015
IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis.
The Journal of experimental medicine
Pallangyo CK,Ziegler PK,Greten FR
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Mon Dec 14 00:00:00 EST 2015
Tamm-Horsfall Protein Regulates Granulopoiesis and Systemic Neutrophil Homeostasis.
Journal of the American Society of Nephrology : JASN
Micanovic R,Chitteti BR,Dagher PC,Srour EF,Khan S,Hato T,Lyle A,Tong Y,Wu XR,El-Achkar TM
48-0032 was used in Flow cytometry/Cell sorting to show that Tamm-Horsfall protein deficiency in mice causes systemic neutrophilia through enhanced granulopoiesis in the bone marrow.
Tue Sep 01 00:00:00 EDT 2015
B cell autophagy mediates TLR7-dependent autoimmunity and inflammation.
Autophagy
Weindel CG,Richey LJ,Bolland S,Mehta AJ,Kearney JF,Huber BT
48-0032 was used in Flow cytometry/Cell sorting to demonstrate that autophagy plays an essential role in TLR7 activation of B cells for the induction of systemic lupus erythematosus.
Mon Apr 18 00:00:00 EDT 2016
Cornea-infiltrating and lymph node dendritic cells contribute to CD4+ T cell expansion after herpes simplex virus-1 ocular infection.
Journal of immunology (Baltimore, Md. : 1950)
Buela KA,Hendricks RL
48-0032 was used in Flow cytometry/Cell sorting to determine the contribution of cornea resident, cornea-infiltrating, and DLN resident dendritic cells (DC) to CD4(+) T cell expansion in DLNs and restimulation in corneas.
Thu Jan 01 00:00:00 EST 2015
Adjuvants may reduce in vivo transfection levels for DNA vaccination in mice leading to reduced antigen-specific CD8+ T cell responses.
Human vaccines & immunotherapeutics
Rose AH,Hoffmann FW,Hara JH,Urschitz J,Moisyadi S,Hoffmann PR,Bertino P
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Mon May 16 00:00:00 EDT 2016
IL-33 Enhances Humoral Immunity Against Chronic HBV Infection Through Activating CD4(+)CXCR5(+) TFH Cells.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Zhao PW,Shi X,Li C,Ayana DA,Niu JQ,Feng JY,Wang J,Jiang YF
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling.
Nature communications
Kang YJ,Bang BR,Han KH,Hong L,Shim EJ,Ma J,Lerner RA,Otsuka M
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Fri Sep 18 00:00:00 EDT 2015
Antibiotics in neonatal life increase murine susceptibility to experimental psoriasis.
Nature communications
Zanvit P,Konkel JE,Jiao X,Kasagi S,Zhang D,Wu R,Chia C,Ajami NJ,Smith DP,Petrosino JF,Abbatiello B,Nakatsukasa H,Chen Q,Belkaid Y,Chen ZJ,Chen W
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2015
Expression of a Chimeric Antigen Receptor in Multiple Leukocyte Lineages in Transgenic Mice.
PloS one
Yong CS,Westwood JA,Schröder J,Papenfuss AT,von Scheidt B,Moeller M,Devaud C,Darcy PK,Kershaw MH
48-0032 was used in Flow cytometry/Cell sorting to generate a mouse model expressing chimeric antigen receptors (CARs) specific for a tumour antigen under a pan-hematopoietic promoter.
Wed Jun 08 00:00:00 EDT 2016
α-1-Antitrypsin (AAT)-modified donor cells suppress GVHD but enhance the GVL effect: a role for mitochondrial bioenergetics.
Blood
Marcondes AM,Karoopongse E,Lesnikova M,Margineantu D,Welte T,Dinarello CA,Hockenbery D,Janciauskiene S,Deeg HJ
48-0032 was used in Flow cytometry/Cell sorting to investigate the role of α-1-antitrypsin in graft-versus-host disease, showing that α-1-Antitrypsin-modified donor cells suppress graft-versus-host disease but enhance the graft-versus-leukemia effect.
Thu Oct 30 00:00:00 EDT 2014
TLR2 engagement on CD4(+) T cells enhances effector functions and protective responses to Mycobacterium tuberculosis.
European journal of immunology
Reba SM,Li Q,Onwuzulike S,Ding X,Karim AF,Hernandez Y,Fulton SA,Harding CV,Lancioni CL,Nagy N,Rodriguez ME,Wearsch PA,Rojas RE
48-0032-82 was used in Flow cytometry/Cell sorting to examine the role of CD4(+) T-cell-expressed TLR2 in Mycobacterium tuberculosis (MTB) Ag-specific T-cell priming and in protection against MTB infection in vivo.
Thu May 01 00:00:00 EDT 2014
Prophylaxis with a respiratory syncytial virus (RSV) anti-G protein monoclonal antibody shifts the adaptive immune response to RSV rA2-line19F infection from Th2 to Th1 in BALB/c mice.
Journal of virology
Boyoglu-Barnum S,Chirkova T,Todd SO,Barnum TR,Gaston KA,Jorquera P,Haynes LM,Tripp RA,Moore ML,Anderson LJ
48-0032 was used in Flow cytometry/Cell sorting to suggest that the RSV G protein not only contributes to disease, but also dampens the host immune response to infection.
Mon Sep 01 00:00:00 EDT 2014
Central role of conventional dendritic cells in regulation of bone marrow release and survival of neutrophils.
Journal of immunology (Baltimore, Md. : 1950)
Jiao J,Dragomir AC,Kocabayoglu P,Rahman AH,Chow A,Hashimoto D,Leboeuf M,Kraus T,Moran T,Carrasco-Avino G,Friedman SL,Merad M,Aloman C
48-0032 was used in Flow cytometry/Cell sorting to investigate the role of dendritic cells in neutrophil homeostasis, showing a central role in regulation of bone marrow release and survival of neutrophils.
Tue Apr 01 00:00:00 EDT 2014
Immune selection of tumor cells in TCR β-chain transgenic mice.
Journal of immunotoxicology
Silaeva YY,Grinenko TS,Vagida MS,Kalinina AA,Khromykh LM,Kazansky DB
48-0032 was used in Flow cytometry/Cell sorting to compare the ability of WT and transgenic, immune-compromised mice to reject EL4 thymoma cells.
Wed Oct 01 00:00:00 EDT 2014
A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking β-glucans.
PloS one
Dong B,Li D,Li R,Chen SC,Liu W,Liu W,Chen L,Chen Y,Zhang X,Tong Z,Xia Y,Xia P,Wang Y,Duan Y
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2015
Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface.
PloS one
Habbeddine M,Verbeke P,Karaz S,Bobé P,Kanellopoulos-Langevin C
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Flow Cytometry
Wed Jun 10 00:00:00 EDT 2015
Exposure to combustion generated environmentally persistent free radicals enhances severity of influenza virus infection.
Particle and fibre toxicology
Lee GI,Saravia J,You D,Shrestha B,Jaligama S,Hebert VY,Dugas TR,Cormier SA
48-0032 was used in Flow cytometry/Cell sorting to study how EPFR-induced oxidative stress resulted in increased presence of Tregs in the lungs and subsequent suppression of adaptive immune response to influenza.
Thu Oct 30 00:00:00 EDT 2014
Chronic thoracic spinal cord injury impairs CD8+ T-cell function by up-regulating programmed cell death-1 expression.
Journal of neuroinflammation
Zha J,Smith A,Andreansky S,Bracchi-Ricard V,Bethea JR
48-0032 was used in Flow cytometry/Cell sorting to investigate CD8+ T-cell function by up-regulating programmed cell death-1 expression in chronic thoracic spinal cord injury.
Tue Apr 01 00:00:00 EDT 2014
Influenza virus-induced lung inflammation was modulated by cigarette smoke exposure in mice.
PloS one
Han Y,Ling MT,Mao H,Zheng J,Liu M,Lam KT,Liu Y,Tu W,Lau YL
48-0032 was used in Flow cytometry/Cell sorting to investigate the effect of cigarette smoke on pandemic H1N1 or H9N2 virus infection, showing that virus-induced lung inflammation was modulated by cigarette smoke exposure.
Wed Oct 29 00:00:00 EDT 2014
Host immunity contributes to the anti-melanoma activity of BRAF inhibitors.
The Journal of clinical investigation
Knight DA,Ngiow SF,Li M,Parmenter T,Mok S,Cass A,Haynes NM,Kinross K,Yagita H,Koya RC,Graeber TG,Ribas A,McArthur GA,Smyth MJ
48-0032 was used in Flow cytometry/Cell sorting to investigate the contribution of host immunity to the anti-melanoma activity of BRAF inhibitors.
Fri Mar 01 00:00:00 EST 2013
Cellular-FLIP, Raji isoform (c-FLIP R) modulates cell death induction upon T-cell activation and infection.
European journal of immunology
Telieps T,Ewald F,Gereke M,Annemann M,Rauter Y,Schuster M,Ueffing N,von Smolinski D,Gruber AD,Bruder D,Schmitz I
48-0032 was used in Flow cytometry/Cell sorting to study the induction of endogenous murine cellular-FLIPR in activated lymphocytes.
Sat Jun 01 00:00:00 EDT 2013
Peyer's patch inducer cells play a leading role in the formation of B and T cell zone architecture.
Journal of immunology (Baltimore, Md. : 1950)
Nakagawa R,Togawa A,Nagasawa T,Nishikawa S
48-0032 was used in Flow cytometry/Cell sorting to analyse evidence that CD3(-)IL-7Rα(+) PP inducer cells are involved in the formation of B and T cell zones in neonatal mice.
Mon Apr 01 00:00:00 EDT 2013
Neuronal and nonneuronal cholinergic structures in the mouse gastrointestinal tract and spleen.
The Journal of comparative neurology
Gautron L,Rutkowski JM,Burton MD,Wei W,Wan Y,Elmquist JK
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Immunofluorescence
Fri Nov 01 00:00:00 EDT 2013
Role of NK cell subsets in organ-specific murine melanoma metastasis.
PloS one
Ballas ZK,Buchta CM,Rosean TR,Heusel JW,Shey MR
48-0032 was used in Flow cytometry/Cell sorting to examine the organ-specific functions of natural killer cells.
Thu Jan 16 00:00:00 EST 2014
Heterologous immunity triggered by a single, latent virus in Mus musculus: combined costimulation- and adhesion- blockade decrease rejection.
PloS one
Beus JM,Hashmi SS,Selvaraj SA,Duan D,Stempora LL,Monday SA,Cheeseman JA,Hamby KM,Speck SH,Larsen CP,Kirk AD,Kean LS
48-0032 was used in Flow cytometry/Cell sorting to study changes in CD8(dim) T cell populations in response to a MHV68 rodent model of latent virus-induced heterologous alloimmunity.
Mon Apr 14 00:00:00 EDT 2014
Dynamic in situ cytometry uncovers T cell receptor signaling during immunological synapses and kinapses in vivo.
Immunity
Moreau HD,Lemaître F,Terriac E,Azar G,Piel M,Lennon-Dumenil AM,Bousso P
48-0032 was used in Flow cytometry/Cell sorting to examine how T cells sense TCR ligands of varying affinities in vivo.
Fri Aug 24 00:00:00 EDT 2012
The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology.
Immunity
Hall AO,Beiting DP,Tato C,John B,Oldenhove G,Lombana CG,Pritchard GH,Silver JS,Bouladoux N,Stumhofer JS,Harris TH,Grainger J,Wojno ED,Wagage S,Roos DS,Scott P,Turka LA,Cherry S,Reiner SL,Cua D,Belkaid Y,Elloso MM,Hunter CA
48-0032 was used in Flow cytometry/Cell sorting to study the promotion of distinct Treg cell populations by the cytokines IL-27 and IFN-y, and the role they play in limiting infection induced pathology.
Fri Sep 21 00:00:00 EDT 2012
Monocytes regulate the mechanism of T-cell death by inducing Fas-mediated apoptosis during bacterial infection.
PLoS pathogens
Daigneault M,De Silva TI,Bewley MA,Preston JA,Marriott HM,Mitchell AM,Mitchell TJ,Read RC,Whyte MK,Dockrell DH
48-0032 was used in Flow cytometry/Cell sorting to elucidate the mechanisms that regulate levels of activated T-cells at sites of acute bacterial infection.
Tue Jan 29 00:00:00 EST 2013
Nitric oxide inhibits the accumulation of CD4+CD44hiTbet+CD69lo T cells in mycobacterial infection.
European journal of immunology
Pearl JE,Torrado E,Tighe M,Fountain JJ,Solache A,Strutt T,Swain S,Appelberg R,Cooper AM
48-0032 was used in Flow cytometry/Cell sorting to support the hypothesis that effector T cells in mycobacterial granulomata are not a uniform effector population but exist in distinct subsets with differential susceptibility to the regulatory effects of nitric oxide.
Sat Dec 01 00:00:00 EST 2012
Cutting edge: tumor-targeting antibodies enhance NKG2D-mediated NK cell cytotoxicity by stabilizing NK cell-tumor cell interactions.
Journal of immunology (Baltimore, Md. : 1950)
Deguine J,Breart B,Lemaître F,Bousso P
48-0032 was used in Flow cytometry/Cell sorting to investigate how natural killer cells integrate signals from antibody-coated targets and stress ligands on tumour cells.
Sat Dec 15 00:00:00 EST 2012
Urea amidolyase (DUR1,2) contributes to virulence and kidney pathogenesis of Candida albicans.
PloS one
Navarathna DH,Lionakis MS,Lizak MJ,Munasinghe J,Nickerson KW,Roberts DD
48-0032 was used in Flow cytometry/Cell sorting to demonstrate that Dur1,2p is important for kidney colonisation during disseminated candidiasis and contributes to subsequent renal failure.
Tue Aug 26 00:00:00 EDT 2014
Prostaglandin E2 suppresses the differentiation of retinoic acid-producing dendritic cells in mice and humans.
The Journal of experimental medicine
Stock A,Booth S,Cerundolo V
48-0032 was used in Flow cytometry/Cell sorting to study how PGE2 stimulates the expression of the inducible cyclic AMP early repressor, which appears to directly inhibit RALDH expression in DCs.
Mon Apr 11 00:00:00 EDT 2011
A role for IL-27 in limiting T regulatory cell populations.
Journal of immunology (Baltimore, Md. : 1950)
Wojno ED,Hosken N,Stumhofer JS,O'Hara AC,Mauldin E,Fang Q,Turka LA,Levin SD,Hunter CA
48-0032 was used in Flow cytometry/Cell sorting to show that mice that overexpress IL-27 had decreased Treg frequencies and developed spontaneous inflammation.
Fri Jul 01 00:00:00 EDT 2011
Increased incidence of endometrioid tumors caused by aberrations in E-cadherin promoter of mismatch repair-deficient mice.
Carcinogenesis
Kovtun IV,Harris KJ,Jatoi A,Jevremovic D
Published figure using CD3 monoclonal antibody (Product # 48-0032-82) in Immunohistochemistry
Fri Jul 01 00:00:00 EDT 2011
Localized delivery of interferon-β by Lactobacillus exacerbates experimental colitis.
PloS one
McFarland AP,Savan R,Wagage S,Addison A,Ramakrishnan K,Karwan M,Duong T,Young HA
48-0032 was used in Flow cytometry/Cell sorting to identify a correlation between the loss/down-regulation of IFNAR1 on DCs and exacerbation of colitis.
Fri Feb 18 00:00:00 EST 2011
Antigen-specific immunity and cross-priming by epithelial ovarian carcinoma-induced CD11b(+)Gr-1(+) cells.
Journal of immunology (Baltimore, Md. : 1950)
Tomihara K,Guo M,Shin T,Sun X,Ludwig SM,Brumlik MJ,Zhang B,Curiel TJ,Shin T
48-0032 was used in Flow cytometry/Cell sorting to investigate CD11b(+)Gr-1(+) cells found in epithelial ovarian cancer-bearing mice, which are induced by ovarian cancer cells and undergo antigen-specific immunity and cross-priming.
Tue Jun 01 00:00:00 EDT 2010
