Product References
Cell-in-cell structure mediates in-cell killing suppressed by CD44.
Cell discovery
Su Y,Huang H,Luo T,Zheng Y,Fan J,Ren H,Tang M,Niu Z,Wang C,Wang Y,Zhang Z,Liang J,Ruan B,Gao L,Chen Z,Melino G,Wang X,Sun Q
11-3351-82 was used in Immunohistochemistry (Paraffin) to identify CIC-mediated "in-cell killing" as a promising strategy for cancer immunotherapy.
Tue Apr 19 00:00:00 EDT 2022
NK cells in hypoxic skin mediate a trade-off between wound healing and antibacterial defence.
Nature communications
Sobecki M,Krzywinska E,Nagarajan S,Audigé A,Hu¿nh K,Zacharjasz J,Debbache J,Kerdiles Y,Gotthardt D,Takeda N,Fandrey J,Sommer L,Sexl V,Stockmann C
Published figure using CD335 (NKp46) monoclonal antibody (Product # 11-3351-82) in Flow Cytometry
Wed Aug 04 00:00:00 EDT 2021
Interferon Lambda Regulates Cellular and Humoral Immunity in Pristane-Induced Lupus.
International journal of molecular sciences
Aschman T,Schaffer S,Biniaris Georgallis SI,Triantafyllopoulou A,Staeheli P,Voll RE
Published figure using CD335 (NKp46) monoclonal antibody (Product # 11-3351-82) in Flow Cytometry
Fri Oct 29 00:00:00 EDT 2021
Fascin inhibitor increases intratumoral dendritic cell activation and anti-cancer immunity.
Cell reports
Wang Y,Song M,Liu M,Zhang G,Zhang X,Li MO,Ma X,Zhang JJ,Huang XY
11-3351-82 was used in Flow Cytometry to investigate the effects of fascin blockade in anti-tumor immune responses in syngeneic mouse models of various cancers.
Tue Apr 06 00:00:00 EDT 2021
Flow cytometry-based ex vivo murine NK cell cytotoxicity assay.
STAR protocols
Wong P,Wagner JA,Berrien-Elliott MM,Schappe T,Fehniger TA
Published figure using CD335 (NKp46) monoclonal antibody (Product # 11-3351-82) in Flow Cytometry
Fri Mar 19 00:00:00 EDT 2021
Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities.
Nature communications
Cho SX,Rudloff I,Lao JC,Pang MA,Goldberg R,Bui CB,McLean CA,Stock M,Klassert TE,Slevogt H,Mangan NE,Cheng W,Fischer D,Gfroerer S,Sandhu MK,Ngo D,Bujotzek A,Lariviere L,Schumacher F,Tiefenthaler G,Beker F,Collins C,Kamlin COF,König K,Malhotra A,Tan K,Theda C,Veldman A,Ellisdon AM,Whisstock JC,Berger PJ,Nold-Petry CA,Nold MF
Published figure using CD335 (NKp46) monoclonal antibody (Product # 11-3351-82) in Flow Cytometry
Fri Nov 13 00:00:00 EST 2020
Novel CD11b+Gr-1+Sca-1+ myeloid cells drive mortality in bacterial infection.
Science advances
Park MY,Kim HS,Lee HY,Zabel BA,Bae YS
Published figure using CD335 (NKp46) monoclonal antibody (Product # 11-3351-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2020
SCGN deficiency results in colitis susceptibility.
eLife
Sifuentes-Dominguez LF,Li H,Llano E,Liu Z,Singla A,Patel AS,Kathania M,Khoury A,Norris N,Rios JJ,Starokadomskyy P,Park JY,Gopal P,Liu Q,Tan S,Chan L,Ross T,Harrison S,Venuprasad K,Baker LA,Jia D,Burstein E
Published figure using CD335 (NKp46) monoclonal antibody (Product # 11-3351-82) in Flow Cytometry
Wed Oct 30 00:00:00 EDT 2019
Synergized regulation of NK cell education by NKG2A and specific Ly49 family members.
Nature communications
Zhang X,Feng J,Chen S,Yang H,Dong Z
11-3351 was used in Flow cytometry/Cell sorting to provide genetic evidence supporting that NKG2A and the inhibitory members of Ly49 family receptors synergize to regulate NK cell education.
Fri Nov 01 00:00:00 EDT 2019
Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells.
JCI insight
Huang A,Shinde PV,Huang J,Senff T,Xu HC,Margotta C,Häussinger D,Willnow TE,Zhang J,Pandyra AA,Timm J,Weggen S,Lang KS,Lang PA
11-3351 was used in Flow cytometry/Cell sorting to show that progranulin (PGRN) can reduce NK cell cytotoxicity through reduction of NK cell expansion, granzyme B transcription, and NK cell-mediated lysis of target cells.
Thu Sep 05 00:00:00 EDT 2019
Myc Cooperates with Ras by Programming Inflammation and Immune Suppression.
Cell
Kortlever RM,Sodir NM,Wilson CH,Burkhart DL,Pellegrinet L,Brown Swigart L,Littlewood TD,Evan GI
11-3351 was used in Flow cytometry/Cell sorting to show that Myc extensively programs an immune suppressive stroma that is obligatory for tumour progression.
Thu Nov 30 00:00:00 EST 2017
A Viral Immunoevasin Controls Innate Immunity by Targeting the Prototypical Natural Killer Cell Receptor Family.
Cell
Aguilar OA,Berry R,Rahim MMA,Reichel JJ,Popović B,Tanaka M,Fu Z,Balaji GR,Lau TNH,Tu MM,Kirkham CL,Mahmoud AB,Mesci A,Krmpotić A,Allan DSJ,Makrigiannis AP,Jonjić S,Rossjohn J,Carlyle JR
11-3351 was used in Flow cytometry/Cell sorting to identify a viral ligand for the inhibitory and activating NKR-P1 receptors.
Thu Mar 23 00:00:00 EDT 2017
DC subset-specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivo.
The Journal of experimental medicine
Lehmann CHK,Baranska A,Heidkamp GF,Heger L,Neubert K,Lühr JJ,Hoffmann A,Reimer KC,Brückner C,Beck S,Seeling M,Kießling M,Soulat D,Krug AB,Ravetch JV,Leusen JHW,Nimmerjahn F,Dudziak D
11-3351 was used in Flow cytometry/Cell sorting to suggest that targeting antigens to FcγRs on DCs may be a promising approach to raise immunogenic or tolerogenic T cell responses to antigens of choice.
Mon May 01 00:00:00 EDT 2017
Local Delivery of OncoVEXmGM-CSF Generates Systemic Antitumor Immune Responses Enhanced by Cytotoxic T-Lymphocyte-Associated Protein Blockade.
Clinical cancer research : an official journal of the American Association for Cancer Research
Moesta AK,Cooke K,Piasecki J,Mitchell P,Rottman JB,Fitzgerald K,Zhan J,Yang B,Le T,Belmontes B,Ikotun OF,Merriam K,Glaus C,Ganley K,Cordover DH,Boden AM,Ponce R,Beers C,Beltran PJ
11-3351 was used in Immunohistochemistry on frozen tissues to characterise local and systemic anti-tumour immune responses driving efficacy in murine syngeneic models.
Sun Oct 15 00:00:00 EDT 2017
Conventional NK cells and ILC1 are partially ablated in the livers of Ncr1 iCreTbx21 fl/fl mice.
Wellcome open research
Cuff AO,Male V
Published figure using CD335 (NKp46) monoclonal antibody (Product # 11-3351-82) in Flow Cytometry
Sat Jan 09 00:00:00 EST 2021
Loss of HIF-1α in natural killer cells inhibits tumour growth by stimulating non-productive angiogenesis.
Nature communications
Krzywinska E,Kantari-Mimoun C,Kerdiles Y,Sobecki M,Isagawa T,Gotthardt D,Castells M,Haubold J,Millien C,Viel T,Tavitian B,Takeda N,Fandrey J,Vivier E,Sexl V,Stockmann C
Published figure using CD335 (NKp46) monoclonal antibody (Product # 11-3351-82) in Flow Cytometry
Fri Nov 17 00:00:00 EST 2017
Antibody-dependent fragmentation is a newly identified mechanism of cell killing in vivo.
Scientific reports
Liew PX,Kim JH,Lee WY,Kubes P
11-3351 was used in Flow cytometry/Cell sorting to investigate a novel antibody-dependent cell death pathway.
Tue Sep 05 00:00:00 EDT 2017
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using CD335 (NKp46) monoclonal antibody (Product # 11-3351-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
IL-33-Dependent Group 2 Innate Lymphoid Cells Promote Cutaneous Wound Healing.
The Journal of investigative dermatology
Rak GD,Osborne LC,Siracusa MC,Kim BS,Wang K,Bayat A,Artis D,Volk SW
11-3351 was used in Flow cytometry/Cell sorting to demonstrate that cutaneous injury promotes an IL-33-dependent group 2 ILC (ILC2) response and that abrogation of this response can impair efficient wound closure.
Mon Feb 01 00:00:00 EST 2016
Natural Killer Cells and Innate Interferon Gamma Participate in the Host Defense against Respiratory Vaccinia Virus Infection.
Journal of virology
Abboud G,Tahiliani V,Desai P,Varkoly K,Driver J,Hutchinson TE,Salek-Ardakani S
11-3351 was used in Flow cytometry/Cell sorting to provide insight on the role of NK cells in initial host defence against Vaccinia Infection and ultimate clearance by interferon gamma.
Fri Jan 01 00:00:00 EST 2016
NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Nature communications
Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z
Published figure using CD335 (NKp46) monoclonal antibody (Product # 11-3351-82) in Flow Cytometry
Wed Sep 07 00:00:00 EDT 2016
Loss of immune tolerance to IL-2 in type 1 diabetes.
Nature communications
Pérol L,Lindner JM,Caudana P,Nunez NG,Baeyens A,Valle A,Sedlik C,Loirat D,Boyer O,Créange A,Cohen JL,Rogner UC,Yamanouchi J,Marchant M,Leber XC,Scharenberg M,Gagnerault MC,Mallone R,Battaglia M,Santamaria P,Hartemann A,Traggiai E,Piaggio E
11-3351 was used in Flow cytometry/Cell sorting to study the role of the loss of immune tolerance to IL-2 in type 1 diabetes.
Thu Oct 06 00:00:00 EDT 2016
Tim-3 negatively mediates natural killer cell function in LPS-induced endotoxic shock.
PloS one
Hou H,Liu W,Wu S,Lu Y,Peng J,Zhu Y,Lu Y,Wang F,Sun Z
11-3351 was used in Flow cytometry/Cell sorting to study the role of Tim-3 in the regulation of natural killer cells following LPS-induced shock.
Mon Jul 06 00:00:00 EDT 2015
CD8+T cell-specific induction of NKG2D receptor by doxorubicin plus interleukin-12 and its contribution to CD8+T cell accumulation in tumors.
Molecular cancer
Hu J,Zhu S,Xia X,Zhang L,Kleinerman ES,Li S
11-3351 was used in Flow cytometry/Cell sorting to explore the impact of NKG2D expression on CD8+T cell infiltration and antitumour efficacy.
Mon Feb 24 00:00:00 EST 2014
Ganciclovir prophylaxis improves late murine cytomegalovirus-induced renal allograft damage.
Transplantation
Shimamura M,Seleme MC,Guo L,Saunders U,Schoeb TR,George JF,Britt WJ
11-3351 was used in Flow cytometry/Cell sorting to examine the lasting effect of Ganciclovir treatment on renal allografts after the discontinuation of prophylaxis.
Tue Jan 15 00:00:00 EST 2013
Preclinical evaluation of engineered oncolytic herpes simplex virus for the treatment of neuroblastoma.
PloS one
Gillory LA,Megison ML,Stewart JE,Mroczek-Musulman E,Nabers HC,Waters AM,Kelly V,Coleman JM,Markert JM,Gillespie GY,Friedman GK,Beierle EA
11-3351 was used in Flow cytometry/Cell sorting to demonstrate that M002 effectively targets neuroblastoma and has potential for use in paediatric treatment.
Wed Jun 11 00:00:00 EDT 2014
Microfibril-associated glycoprotein 2 (MAGP2) loss of function has pleiotropic effects in vivo.
The Journal of biological chemistry
Combs MD,Knutsen RH,Broekelmann TJ,Toennies HM,Brett TJ,Miller CA,Kober DL,Craft CS,Atkinson JJ,Shipley JM,Trask BC,Mecham RP
11-3351 was used in Flow cytometry/Cell sorting to demonstrate that loss of MAGP2 expression in vivo has pleiotropic effects potentially related to the ability of MAGP2 to regulate growth factors or participate in cell signaling.
Fri Oct 04 00:00:00 EDT 2013
NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors.
Nature medicine
Alvarez-Breckenridge CA,Yu J,Price R,Wojton J,Pradarelli J,Mao H,Wei M,Wang Y,He S,Hardcastle J,Fernandez SA,Kaur B,Lawler SE,Vivier E,Mandelboim O,Moretta A,Caligiuri MA,Chiocca EA
11-3351 was used in Flow cytometry/Cell sorting to demonstrate that glioblastoma virotherapy is limited partially by an antiviral NK cell response involving specific NCRs, uncovering new potential targets to enhance cancer virotherapy.
Sat Dec 01 00:00:00 EST 2012
Differential requirements for IRF-2 in generation of CD1d-independent T cells bearing NK cell receptors.
Journal of immunology (Baltimore, Md. : 1950)
Notake T,Horisawa S,Sanjo H,Miyagawa S,Hida S,Taki S
11-3351 was used in Flow cytometry/Cell sorting to investigate the mechanisms behind the generation and function of NKR(+) T cells.
Tue May 15 00:00:00 EDT 2012
Genomic expression analyses reveal lysosomal, innate immunity proteins, as disease correlates in murine models of a lysosomal storage disorder.
PloS one
Alam MS,Getz M,Safeukui I,Yi S,Tamez P,Shin J,Velázquez P,Haldar K
11-3351 was used in Flow cytometry/Cell sorting to identify Niemann-Pick Type C disease severity correlates, showing that expression of lysosomal, innate immunity proteins correlate with severity.
Mon Apr 01 00:00:00 EDT 2013
IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium.
Nature immunology
Ota N,Wong K,Valdez PA,Zheng Y,Crellin NK,Diehl L,Ouyang W
Sun Aug 28 00:00:00 EDT 2011
Monocytes control natural killer cell differentiation to effector phenotypes.
Blood
Soderquest K,Powell N,Luci C,van Rooijen N,Hidalgo A,Geissmann F,Walzer T,Lord GM,Martín-Fontecha A
11-3351 was used in Flow cytometry/Cell sorting to investigate whether NK-cell subsets have specific roles during antitumour responses and what signals drive their terminal maturation.
Thu Apr 28 00:00:00 EDT 2011
Distinct MHC class I-dependent NK cell-activating receptors control cytomegalovirus infection in different mouse strains.
The Journal of experimental medicine
Pyzik M,Charbonneau B,Gendron-Pontbriand EM,Babić M,Krmpotić A,Jonjić S,Vidal SM
11-3351 was used in Flow cytometry/Cell sorting to study how multiple activating Ly49 receptors may participate in H-2-dependent recognition of MCMV infection, providing a common mechanism of NK cell-mediated resistance against viral infection.
Mon May 09 00:00:00 EDT 2011
Chronic cigarette smoke exposure primes NK cell activation in a mouse model of chronic obstructive pulmonary disease.
Journal of immunology (Baltimore, Md. : 1950)
Motz GT,Eppert BL,Wortham BW,Amos-Kroohs RM,Flury JL,Wesselkamper SC,Borchers MT
11-3351 was used in Flow cytometry/Cell sorting to demonstrate an entirely novel mechanism of NK cell activation resulting from chronic cigarette smoke exposure.
Thu Apr 15 00:00:00 EDT 2010
CCR7 deficiency leads to leukocyte activation and increased clearance in response to pulmonary Pseudomonas aeruginosa infection.
Infection and immunity
Eppert BL,Motz GT,Wortham BW,Flury JL,Borchers MT
11-3351 was used in Flow cytometry/Cell sorting to investigate the roles of CCR7 in the host defense against pulmonary infection, showing that CCR7 deficiency leads to leukocyte activation and increased infection clearance.
Sat May 01 00:00:00 EDT 2010
Impaired NK cytolytic activity and enhanced tumor growth in NK lytic-associated molecule-deficient mice.
Journal of immunology (Baltimore, Md. : 1950)
Hoover RG,Gullickson G,Kornbluth J
11-3351 was used in Flow cytometry/Cell sorting to indicate that NK lytic-associated molecule-deficient mice have diminished capacity to control tumour metastases.
Tue Dec 01 00:00:00 EST 2009
