Product References
Deletion of CD36 exhibits limited impact on normal hematopoiesis and the leukemia microenvironment.
Cellular & molecular biology letters
Meng Y,Pospiech M,Ali A,Chandwani R,Vergel M,Onyemaechi S,Yaghmour G,Lu R,Alachkar H
45-0453-82 was used in Flow cytometry/Cell sorting to investigate whether targeting CD36 has any detrimental impact on normal hematopoietic cells.
Wed May 24 00:00:00 EDT 2023
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J
45-0453-82 was used in Flow Cytometry to establish both direct and indirect roles for ILC2 in peri-aortic CaPO4 injury-induced mouse abdominal aortic aneurysms.
Wed Mar 01 00:00:00 EST 2023
R274X-mutated Phf6 increased the self-renewal and skewed T cell differentiation of hematopoietic stem cells.
iScience
Lan Y,Yuan S,Guo T,Hou S,Zhao F,Yang W,Cao Y,Chu Y,Jiang E,Yuan W,Wang X
45-0453-82 was used in Flow cytometry/Cell sorting to demonstrate that Phf6R274X plays a critical role in fine-tuning T cells and HSC homeostasis.
Fri Jun 16 00:00:00 EDT 2023
Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development.
Nature immunology
Scherer S,Oberle SG,Kanev K,Gerullis AK,Wu M,de Almeida GP,Puleston DJ,Baixauli F,Aly L,Greco A,Nizharadze T,Becker NB,Hoesslin MV,Donhauser LV,Berner J,Chu T,McNamara HA,Esencan Z,Roelli P,Wurmser C,Kleiter I,Vehreschild MJGT,Mayer CA,Knolle P,Klingenspor M,Fumagalli V,Iannacone M,Prlic M,Korn T,Pearce EL,Höfer T,Schulz AM,Zehn D
45-0453-82 was used in Flow cytometry/Cell sorting to show memory T cell precursors are resistant to pyrimidine starvation.
Wed Mar 01 00:00:00 EST 2023
Group 2 innate lymphoid cells protect mouse heart from myocardial infarction injury via interleukin 5, eosinophils, and dendritic cells.
Cardiovascular research
Liu T,Meng Z,Liu J,Li J,Zhang Y,Deng Z,Luo S,Wang M,Huang Q,Zhang S,Fendt P,Devouassoux J,Li D,McKenzie ANJ,Nahrendorf M,Libby P,Guo J,Shi GP
45-0453-82 was used in Flow cytometry/Cell sorting to reveal an indirect cardiac reparative role of ILC2 in post-MI hearts via the IL5, EOS, and DC mechanism.
Tue May 02 00:00:00 EDT 2023
Tet-mediated DNA demethylation regulates specification of hematopoietic stem and progenitor cells during mammalian embryogenesis.
Science advances
Ma L,Tang Q,Gao X,Lee J,Lei R,Suzuki M,Zheng D,Ito K,Frenette PS,Dawlaty MM
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Fri Mar 04 00:00:00 EST 2022
Viral infection engenders bona fide and bystander subsets of lung-resident memory B cells through a permissive mechanism.
Immunity
Gregoire C,Spinelli L,Villazala-Merino S,Gil L,Holgado MP,Moussa M,Dong C,Zarubica A,Fallet M,Navarro JM,Malissen B,Milpied P,Gaya M
45-0453-82 was used in Flow cytometry/Cell sorting to find that combining influenza and SARS-CoV-2 infection with fluorescent-reporter mice produce distinct subsets of MBCs colonized the lung peribronchial niche after infection.
Tue Jul 12 00:00:00 EDT 2022
SETD2 Haploinsufficiency Enhances Germinal Center-Associated AICDA Somatic Hypermutation to Drive B-cell Lymphomagenesis.
Cancer discovery
Leung W,Teater M,Durmaz C,Meydan C,Chivu AG,Chadburn A,Rice EJ,Muley A,Camarillo JM,Arivalagan J,Li Z,Flowers CR,Kelleher NL,Danko CG,Imielinski M,Dave SS,Armstrong SA,Mason CE,Melnick AM
45-0453-82 was used in Flow cytometry/Cell sorting to define a B cell-specific oncogenic effect of SETD2 heterozygous mutation, which unleashes AICDA mutagenesis of nontemplate strand DNA in the GC reaction, resulting in lymphomas with heavy mutational burden.
Wed Jul 06 00:00:00 EDT 2022
Diverging regulation of Bach2 protein and RNA expression determine cell fate in early B cell response.
Cell reports
Hu Q,Xu T,Zhang M,Zhang H,Liu Y,Li HB,Chen C,Zheng J,Zhang Z,Li F,Shen N,Zhang W,Melnick A,Huang C
45-0453-82 was used in Flow cytometry/Cell sorting to reveal that differential dynamics of Bach2 protein and transcripts in activated B cells control their cell-fate outcomes and imprint the fates of their descendant effector cells.
Tue Jul 05 00:00:00 EDT 2022
Meningeal lymphatic drainage promotes T cell responses against Toxoplasma gondii but is dispensable for parasite control in the brain.
eLife
Kovacs MA,Cowan MN,Babcock IW,Sibley LA,Still K,Batista SJ,Labuzan SA,Sethi I,Harris TH
45-0453-82 was used in Flow cytometry/Cell sorting to reveal that CNS lymphatic drainage supports the development of peripheral T cell responses against T. gondii but remains dispensable for immune protection of the brain.
Wed Dec 21 00:00:00 EST 2022
cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory.
Science immunology
Christian DA,Adams TA,Shallberg LA,Phan AT,Smith TE,Abraha M,Perry J,Ruthel G,Clark JT,Pritchard GH,Aronson LR,Gossa S,McGavern DB,Kedl RM,Hunter CA
45-0453-82 was used in Flow Cytometry to investigate how conventional type 1 dendritic cells (cDC1s) in the peritoneal cavity's omentum coordinate innate responses to microbial challenge and provide secondary signals required for CD8+ T cell expansion and memory formation, particularly after intraperitoneal immunization with Toxoplasma gondii.
Fri Sep 30 00:00:00 EDT 2022
Protocol to establish a stable MLL-AF9_AML mouse model.
STAR protocols
Lu J,Zhao H,Yang L,Jiang X
45-0453-82 was used in Flow cytometry/Cell sorting to describe a mouse MLL-AF9_AML model to investigate Acute myeloid leukemia.
Fri Sep 16 00:00:00 EDT 2022
Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation.
Nature immunology
Rivas MA,Meydan C,Chin CR,Challman MF,Kim D,Bhinder B,Kloetgen A,Viny AD,Teater MR,McNally DR,Doane AS,Béguelin W,Fernández MTC,Shen H,Wang X,Levine RL,Chen Z,Tsirigos A,Elemento O,Mason CE,Melnick AM
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
The Journal of experimental medicine
Ho TT,Dellorusso PV,Verovskaya EV,Bakker ST,Flach J,Smith LK,Ventura PB,Lansinger OM,Hérault A,Zhang SY,Kang YA,Mitchell CA,Villeda SA,Passegué E
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling.
Cell reports
Young IC,Wu B,Andricovich J,Chuang ST,Li R,Tzatsos A,Wu RC,Wu MY
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Tue Nov 23 00:00:00 EST 2021
Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies.
Cell reports
Seydoux E,Wan YH,Feng J,Wall A,Aljedani S,Homad LJ,MacCamy AJ,Weidle C,Gray MD,Brumage L,Taylor JJ,Pancera M,Stamatatos L,McGuire AT
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Tue May 04 00:00:00 EDT 2021
Ddb1 Is Essential for the Expansion of CD4+ Helper T Cells by Regulating Cell Cycle Progression and Cell Death.
Frontiers in immunology
Yang L,Chen W,Li L,Xiao Y,Fan S,Zhang Q,Xia T,Li M,Hong Y,Zhao T,Li Q,Liu WH,Xiao N
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Mon Dec 20 00:00:00 EST 2021
Inhibition of Rag GTPase signaling in mice suppresses B cell responses and lymphomagenesis with minimal detrimental trade-offs.
Cell reports
Ortega-Molina A,Lebrero-Fernández C,Sanz A,Deleyto-Seldas N,Plata-Gómez AB,Menéndez C,Graña-Castro O,Caleiras E,Efeyan A
45-0453-82 was used in Flow Cytometry to support the efficacy and safety of moderate inhibition of nutrient signaling against pathological B cells.
Tue Jul 13 00:00:00 EDT 2021
Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism.
Nature communications
Fu Z,Dean JW,Xiong L,Dougherty MW,Oliff KN,Chen ZE,Jobin C,Garrett TJ,Zhou L
45-0453-82 was used in Flow Cytometry to show that IL-22, a cytokine produced by RORγt+ lymphocytes inhibits IL-13-induced tuft cell differentiation in vitro, and suppresses the tuft cell-type 2 immune circuit and small intestine lengthening in vivo, highlighting its key role in gut tissue remodeling.
Thu Jul 22 00:00:00 EDT 2021
The concerted change in the distribution of cell cycle phases and zone composition in germinal centers is regulated by IL-21.
Nature communications
Zotos D,Quast I,Li-Wai-Suen CSN,McKenzie CI,Robinson MJ,Kan A,Smyth GK,Hodgkin PD,Tarlinton DM
45-0453-82 was used in Flow Cytometry to investigate regulation of cell cycle and germinal centres.
Thu Dec 09 00:00:00 EST 2021
TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate.
Cell
Venturutti L,Teater M,Zhai A,Chadburn A,Babiker L,Kim D,Béguelin W,Lee TC,Kim Y,Chin CR,Yewdell WT,Raught B,Phillip JM,Jiang Y,Staudt LM,Green MR,Chaudhuri J,Elemento O,Farinha P,Weng AP,Nissen MD,Steidl C,Morin RD,Scott DW,Privé GG,Melnick AM
45-0453-82 was used in Flow Cytometry to show that TBL1XR1 mutations skew the humoral immune response toward generating abnormal immature memory B cells (MB), while impairing plasma cell differentiation.
Thu Jul 23 00:00:00 EDT 2020
Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics.
Immunity
Zenke S,Palm MM,Braun J,Gavrilov A,Meiser P,Böttcher JP,Beyersdorf N,Ehl S,Gerard A,Lämmermann T,Schumacher TN,Beltman JB,Rohr JC
45-0453 was used in Flow cytometry/Cell sorting to conclude that CD8+ T cell-population-intrinsic mechanisms regulate cellular behavior, thereby promoting robustness of population dynamics.
Tue Feb 18 00:00:00 EST 2020
Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response.
Cancer cell
Béguelin W,Teater M,Meydan C,Hoehn KB,Phillip JM,Soshnev AA,Venturutti L,Rivas MA,Calvo-Fernández MT,Gutierrez J,Camarillo JM,Takata K,Tarte K,Kelleher NL,Steidl C,Mason CE,Elemento O,Allis CD,Kleinstein SH,Melnick AM
45-0453 was used in Flow cytometry/Cell sorting to show that EZH2 mutations initiate FL by attenuating germinal center(GC) B cell requirement for T cell help and driving slow expansion of GC centrocytes that become enmeshed with and dependent on follicular dendritic cells.
Mon May 11 00:00:00 EDT 2020
Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells.
The Journal of clinical investigation
Khiew SH,Jain D,Chen J,Yang J,Yin D,Young JS,Dent A,Sciammas R,Alegre ML,Chong AS
45-0453 was used in Flow cytometry/Cell sorting to showed that alloreactive B cells were not deleted but rapidly lost their ability to differentiate into germinal center B cells and secrete donor-specific antibodies., by using a murine model of heart tolerance.
Wed Jul 01 00:00:00 EDT 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
RIPK3 and Caspase-1/11 Are Necessary for Optimal Antigen-Specific CD8 T Cell Response Elicited by Genetically Modified Listeria monocytogenes.
Frontiers in immunology
Rana A,de Almeida FC,Paico Montero HA,Gonzales Carazas MM,Bortoluci KR,Sad S,Amarante-Mendes GP
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Fri Mar 26 00:00:00 EDT 2021
Critical role of WNK1 in MYC-dependent early mouse thymocyte development.
eLife
Köchl R,Vanes L,Llorian Sopena M,Chakravarty P,Hartweger H,Fountain K,White A,Cowan J,Anderson G,Tybulewicz VL
45-0453 was used in Flow cytometry/Cell sorting to ind that WNK1 is required for the transition of double negative (DN) thymocytes through the β-selection checkpoint and subsequent proliferation and differentiation into double positive (DP) thymocytes.
Wed Oct 14 00:00:00 EDT 2020
SHP-1 Regulates Antigen Cross-Presentation and Is Exploited by Leishmania to Evade Immunity.
Cell reports
Khouili SC,Cook ECL,Hernández-García E,Martínez-López M,Conde-Garrosa R,Iborra S
45-0453 was used in Flow cytometry/Cell sorting to demonstrate that SHP-1 inhibition improves CD11c+ cell-based vaccination against the parasite.
Tue Dec 01 00:00:00 EST 2020
Engineering monocyte/macrophage-specific glucocerebrosidase expression in human hematopoietic stem cells using genome editing.
Nature communications
Scharenberg SG,Poletto E,Lucot KL,Colella P,Sheikali A,Montine TJ,Porteus MH,Gomez-Ospina N
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Fri Jul 03 00:00:00 EDT 2020
Salt Sensing by Serum/Glucocorticoid-Regulated Kinase 1 Promotes Th17-like Inflammatory Adaptation of Foxp3+ Regulatory T Cells.
Cell reports
Yang YH,Istomine R,Alvarez F,Al-Aubodah TA,Shi XQ,Takano T,Thornton AM,Shevach EM,Zhang J,Piccirillo CA
45-0453-82 was used in Flow Cytometry to show that high salt (HS) drives thymic Treg cells to adopt a T helper type 17 (Th17)-like phenotype and enhances generation of Th17-like induced Treg cells in a SGK1-dependent manner, all the while maintaining suppressive function.
Tue Feb 04 00:00:00 EST 2020
Loss of testosterone impairs anti-tumor neutrophil function.
Nature communications
Markman JL,Porritt RA,Wakita D,Lane ME,Martinon D,Noval Rivas M,Luu M,Posadas EM,Crother TR,Arditi M
45-0453-82 was used in Flow cytometry/Cell sorting to show that in castrated male mice, neutrophil maturation and function are impaired, leading to elevated metastatic burden in two models of melanoma.
Tue Mar 31 00:00:00 EDT 2020
Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity.
Immunity
Martínez-López M,Iborra S,Conde-Garrosa R,Mastrangelo A,Danne C,Mann ER,Reid DM,Gaboriau-Routhiau V,Chaparro M,Lorenzo MP,Minnerup L,Saz-Leal P,Slack E,Kemp B,Gisbert JP,Dzionek A,Robinson MJ,Rupérez FJ,Cerf-Bensussan N,Brown GD,Bernardo D,LeibundGut-Landmann S,Sancho D
45-0453-82 was used in Flow Cytometry to conclude that sensing of commensals by Mincle and Syk signaling in CD11c+ cells reinforces intestinal immune barrier and promotes host-microbiota mutualism, preventing systemic inflammation.
Tue Feb 19 00:00:00 EST 2019
CD160 serves as a negative regulator of NKT cells in acute hepatic injury.
Nature communications
Kim TJ,Park G,Kim J,Lim SA,Kim J,Im K,Shin MH,Fu YX,Del Rio ML,Rodriguez-Barbosa JI,Yee C,Suh KS,Kim SJ,Ha SJ,Lee KM
45-0453-82 was used in Flow cytometry/Cell sorting to show that CD160 is not essential for NKT cell development.
Mon Jul 22 00:00:00 EDT 2019
Immune regeneration in irradiated mice is not impaired by the absence of DPP9 enzymatic activity.
Scientific reports
Gall MG,Zhang HE,Lee Q,Jolly CJ,McCaughan GW,Cook A,Roediger B,Gorrell MD
45-0453 was used in Flow cytometry/Cell sorting to study the relative importance of intracellular protease dipeptidyl peptidase 9 in antigen presentation.
Mon May 13 00:00:00 EDT 2019
Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia.
Nature medicine
Zhang B,Nguyen LXT,Li L,Zhao D,Kumar B,Wu H,Lin A,Pellicano F,Hopcroft L,Su YL,Copland M,Holyoake TL,Kuo CJ,Bhatia R,Snyder DS,Ali H,Stein AS,Brewer C,Wang H,McDonald T,Swiderski P,Troadec E,Chen CC,Dorrance A,Pullarkat V,Yuan YC,Perrotti D,Carlesso N,Forman SJ,Kortylewski M,Kuo YH,Marcucci G
45-0453 was used in Flow cytometry/Cell sorting to demonstrate how bone marrow endothelial cells supply miR-126 to leukemia stem cells in chronic myelogenous leukemia which modulates their quiescence and self-renewal.
Tue May 01 00:00:00 EDT 2018
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
Critical Role for the Microbiota in CX3CR1+ Intestinal Mononuclear Phagocyte Regulation of Intestinal T Cell Responses.
Immunity
Kim M,Galan C,Hill AA,Wu WJ,Fehlner-Peach H,Song HW,Schady D,Bettini ML,Simpson KW,Longman RS,Littman DR,Diehl GE
45-0453 was used in Flow cytometry/Cell sorting to identify a cellular mechanism by which the microbiota limits intestinal inflammation and promotes tissue homeostasis.
Tue Jul 17 00:00:00 EDT 2018
A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion.
Immunity
Xia P,Wang S,Ye B,Du Y,Li C,Xiong Z,Qu Y,Fan Z
45-0453 was used in Flow cytometry/Cell sorting to study circular RNA-mediated maintenance of hematopoeitic stem cell homeostasis.
Tue Apr 17 00:00:00 EDT 2018
The H3K4 methyltransferase Setd1b is essential for hematopoietic stem and progenitor cell homeostasis in mice.
eLife
Schmidt K,Zhang Q,Tasdogan A,Petzold A,Dahl A,Arneth BM,Slany R,Fehling HJ,Kranz A,Stewart AF,Anastassiadis K
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Tue Jun 19 00:00:00 EDT 2018
An immune cell spray (ICS) formulation allows for the delivery of functional monocyte/macrophages.
Scientific reports
Beneke V,Küster F,Neehus AL,Hesse C,Lopez-Rodriguez E,Haake K,Rafiei Hashtchin A,Schott JW,Walter D,Braun A,Wolkers WF,Ackermann M,Lachmann N
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Fri Nov 02 00:00:00 EDT 2018
Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression.
Cell
Cimmino L,Dolgalev I,Wang Y,Yoshimi A,Martin GH,Wang J,Ng V,Xia B,Witkowski MT,Mitchell-Flack M,Grillo I,Bakogianni S,Ndiaye-Lobry D,Martín MT,Guillamot M,Banh RS,Xu M,Figueroa ME,Dickins RA,Abdel-Wahab O,Park CY,Tsirigos A,Neel BG,Aifantis I
45-0453 was used in Flow cytometry/Cell sorting to determine the role of TET2 deficiency in leukaemia stem cell maintenance.
Thu Sep 07 00:00:00 EDT 2017
Biopolymers codelivering engineered T cells and STING agonists can eliminate heterogeneous tumors.
The Journal of clinical investigation
Smith TT,Moffett HF,Stephan SB,Opel CF,Dumigan AG,Jiang X,Pillarisetty VG,Pillai SPS,Wittrup KD,Stephan MT
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.
The Journal of experimental medicine
Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Mon Jun 05 00:00:00 EDT 2017
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Thu Aug 25 00:00:00 EDT 2016
TGF-β receptor maintains CD4 T helper cell identity during chronic viral infections.
The Journal of clinical investigation
Lewis GM,Wehrens EJ,Labarta-Bajo L,Streeck H,Zuniga EI
45-0453 was used in Flow cytometry/Cell sorting to uncover an eomesodermin-driven CD4 T cell program that is continuously suppressed by TGF-β signalling.
Mon Oct 03 00:00:00 EDT 2016
NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20.
The Journal of experimental medicine
Drennan MB,Govindarajan S,Verheugen E,Coquet JM,Staal J,McGuire C,Taghon T,Leclercq G,Beyaert R,van Loo G,Lambrecht BN,Elewaut D
45-0453 was used in Flow cytometry/Cell sorting to show that negative regulation of TCR signalling during NKT development controls the differentiation and survival of NKT1 and NKT2 cells.
Mon Sep 19 00:00:00 EDT 2016
Artery Tertiary Lymphoid Organs Control Multilayered Territorialized Atherosclerosis B-Cell Responses in Aged ApoE-/- Mice.
Arteriosclerosis, thrombosis, and vascular biology
Srikakulapu P,Hu D,Yin C,Mohanta SK,Bontha SV,Peng L,Beer M,Weber C,McNamara CA,Grassia G,Maffia P,Manz RA,Habenicht AJ
45-0453 was used in Flow cytometry/Cell sorting to study how artery tertiary lymphoid organs can orchestrate B-cell responses in the diseased aorta.
Wed Jun 01 00:00:00 EDT 2016
Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.
Stem cell reports
Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Tue Aug 09 00:00:00 EDT 2016
MEK1 is required for the development of NRAS-driven leukemia.
Oncotarget
Nowacka JD,Baumgartner C,Pelorosso C,Roth M,Zuber J,Baccarini M
45-0453 was used in Flow cytometry/Cell sorting to consider the use of MEK1 as a tumour suppressor in the context of leukaemogenesis.
Tue Dec 06 00:00:00 EST 2016
IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance.
Nature immunology
Basu R,Whitley SK,Bhaumik S,Zindl CL,Schoeb TR,Benveniste EN,Pear WS,Hatton RD,Weaver CT
45-0453 was used in Flow cytometry/Cell sorting to assess the ability of IL-1 to override retinoic acid-mediated expression of the transcription factor Foxp3 and induce protective TH17 cell responses.
Sun Mar 01 00:00:00 EST 2015
MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice.
Proceedings of the National Academy of Sciences of the United States of America
Wu L,Li N,Zhang M,Xue SL,Cassady K,Lin Q,Riggs AD,Zeng D
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Tue Dec 29 00:00:00 EST 2015
Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis.
Nature communications
Xue J,Sharma V,Hsieh MH,Chawla A,Murali R,Pandol SJ,Habtezion A
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Mon May 18 00:00:00 EDT 2015
Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages.
Cell
Haldar M,Kohyama M,So AY,Kc W,Wu X,Briseño CG,Satpathy AT,Kretzer NM,Arase H,Rajasekaran NS,Wang L,Egawa T,Igarashi K,Baltimore D,Murphy TL,Murphy KM
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Thu Mar 13 00:00:00 EDT 2014
WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.
The Journal of experimental medicine
Xia P,Wang S,Huang G,Zhu P,Li M,Ye B,Du Y,Fan Z
45-0453 was used in Flow cytometry/Cell sorting to show that conditional WASH deletion in the haematopoietic system causes defective blood production of the host.
Mon Sep 22 00:00:00 EDT 2014
Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4⁺ T cell immunity.
Nature immunology
Reis BS,Rogoz A,Costa-Pinto FA,Taniuchi I,Mucida D
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
Arrayed lentiviral barcoding for quantification analysis of hematopoietic dynamics.
Stem cells (Dayton, Ohio)
Grosselin J,Sii-Felice K,Payen E,Chretien S,Tronik-Le Roux D,Leboulch P
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2013
Inhibiting TGFβ1 has a protective effect on mouse bone marrow suppression following ionizing radiation exposure in vitro.
Journal of radiation research
Zhang H,Wang YA,Meng A,Yan H,Wang X,Niu J,Li J,Wang H
45-0453 was used in Flow cytometry/Cell sorting to examine if the TGF1 inhibitor, SB431542, can mitigate ionizing radiation-induced bone marrow suppression, showing that inhibition has a protective effect.
Mon Jul 01 00:00:00 EDT 2013
N-cadherin in osteolineage cells is not required for maintenance of hematopoietic stem cells.
Blood
Greenbaum AM,Revollo LD,Woloszynek JR,Civitelli R,Link DC
45-0453 was used in Flow cytometry/Cell sorting to investigate whether N-cadherin expression on osteoblast lineage cells regulates HSC function and quiescence, showing that it is not required.
Thu Jul 12 00:00:00 EDT 2012
A germinal center-independent pathway generates unswitched memory B cells early in the primary response.
The Journal of experimental medicine
Taylor JJ,Pape KA,Jenkins MK
45-0453 was used in Flow cytometry/Cell sorting to assess the relative contributions of GC-dependent or GC-independent pathways to the polyclonal memory B cell pool.
Mon Mar 12 00:00:00 EDT 2012
In vitro Ag Cross-presentation and in vivo Ag Cross-presentation by Dendritic Cells in the Mouse.
Bio-protocol
Ghosh M,Shapiro LH
Published figure using CD45.1 monoclonal antibody (Product # 45-0453-82) in Flow Cytometry
Thu Dec 20 00:00:00 EST 2012
A role for IL-27 in limiting T regulatory cell populations.
Journal of immunology (Baltimore, Md. : 1950)
Wojno ED,Hosken N,Stumhofer JS,O'Hara AC,Mauldin E,Fang Q,Turka LA,Levin SD,Hunter CA
45-0453 was used in Flow cytometry/Cell sorting to show that mice that overexpress IL-27 had decreased Treg frequencies and developed spontaneous inflammation.
Fri Jul 01 00:00:00 EDT 2011
