Product References
A high OXPHOS CD8 T cell subset is predictive of immunotherapy resistance in melanoma patients.
The Journal of experimental medicine
Li C,Phoon YP,Karlinsey K,Tian YF,Thapaliya S,Thongkum A,Qu L,Matz AJ,Cameron M,Cameron C,Menoret A,Funchain P,Song JM,Diaz-Montero CM,Tamilselvan B,Golden JB,Cartwright M,Rodriguez A,Bonin C,Vella A,Zhou B,Gastman BR
MHCD0817 was used in Flow cytometry/Cell sorting to conclude that CD8+ TOXPHOS cells represent a critical immune population to assess ICI response with the potential to be a new target to improve outcomes in melanoma patients.
Mon Jan 03 00:00:00 EST 2022
Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates.
PLoS pathogens
Cai F,Chen WH,Wu W,Jones JA,Choe M,Gohain N,Shen X,LaBranche C,Eaton A,Sutherland L,Lee EM,Hernandez GE,Wu NR,Scearce R,Seaman MS,Moody MA,Santra S,Wiehe K,Tomaras GD,Wagh K,Korber B,Bonsignori M,Montefiori DC,Haynes BF,de Val N,Joyce MG,Saunders KO
MHCD0817 was used in Flow Cytometry to support rational vaccine design for HIV-1 that aims to reproducibly elicit, in genetically diverse primates, nAbs with specific paratope structures capable of binding conserved epitopes.
Tue Jun 01 00:00:00 EDT 2021
Protein/AS01B vaccination elicits stronger, more Th2-skewed antigen-specific human T follicular helper cell responses than heterologous viral vectors.
Cell reports. Medicine
Nielsen CM,Ogbe A,Pedroza-Pacheco I,Doeleman SE,Chen Y,Silk SE,Barrett JR,Elias SC,Miura K,Diouf A,Bardelli M,Dabbs RA,Barfod L,Long CA,Haynes BF,Payne RO,Minassian AM,Bradley T,Draper SJ,Borrow P
MHCD0817 was used in Flow Cytometry to highlight the impact of vaccine platform on the cTfh cell response driving humoral immunity, associating a high-magnitude, Th2-biased cTfh response with potent antibody production.
Tue Mar 16 00:00:00 EDT 2021
Protein/AS01B vaccination elicits stronger, more Th2-skewed antigen-specific human T follicular helper cell responses than heterologous viral vectors.
Cell reports. Medicine
Nielsen CM,Ogbe A,Pedroza-Pacheco I,Doeleman SE,Chen Y,Silk SE,Barrett JR,Elias SC,Miura K,Diouf A,Bardelli M,Dabbs RA,Barfod L,Long CA,Haynes BF,Payne RO,Minassian AM,Bradley T,Draper SJ,Borrow P
MHCD0817 was used in Flow Cytometry to highlight the impact of vaccine platform on the cTfh cell response driving humoral immunity, associating a high-magnitude, Th2-biased cTfh response with potent antibody production.
Tue Mar 16 00:00:00 EDT 2021
Single-Cell Analysis Reveals Fibroblast Clusters Linked to Immunotherapy Resistance in Cancer.
Cancer discovery
Kieffer Y,Hocine HR,Gentric G,Pelon F,Bernard C,Bourachot B,Lameiras S,Albergante L,Bonneau C,Guyard A,Tarte K,Zinovyev A,Baulande S,Zalcman G,Vincent-Salomon A,Mechta-Grigoriou F
MHCD0817 was used in Flow cytometry/Cell sorting to provide a significant advance in characterizing and understanding FAP+ CAF in cancer.
Tue Sep 01 00:00:00 EDT 2020
Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations.
Nature communications
Han Q,Jones JA,Nicely NI,Reed RK,Shen X,Mansouri K,Louder M,Trama AM,Alam SM,Edwards RJ,Bonsignori M,Tomaras GD,Korber B,Montefiori DC,Mascola JR,Seaman MS,Haynes BF,Saunders KO
MHCD0817 was used in Flow cytometry/Cell sorting to determine that open conformations of Env with V3 exposed are present on a subset of otherwise neutralization-resistant virions, therefore neutralization of tier 2 HIV-1 does not always indicate bnAb induction.
Mon Jul 01 00:00:00 EDT 2019
Non-conventional Inhibitory CD4+Foxp3-PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity.
Cancer cell
Zappasodi R,Budhu S,Hellmann MD,Postow MA,Senbabaoglu Y,Manne S,Gasmi B,Liu C,Zhong H,Li Y,Huang AC,Hirschhorn-Cymerman D,Panageas KS,Wherry EJ,Merghoub T,Wolchok JD
MHCD0817 was used in Flow cytometry/Cell sorting to provide evidence that mouse and human circulating and intra-tumor 4PD1hi inhibit T cell functions in a PD-1/PD-L1 dependent fashion and resemble follicular helper T cell-like cells.
Mon Jun 11 00:00:00 EDT 2018
Correlation of APRIL with production of inflammatory cytokines during acute malaria in the Brazilian Amazon.
Immunity, inflammation and disease
Pinna RA,Dos Santos AC,Perce-da-Silva DS,da Silva LA,da Silva RNR,Alves MR,Santos F,de Oliveira Ferreira J,Lima-Junior JC,Villa-Verde DM,De Luca PM,Carvalho-Pinto CE,Banic DM
MHCD0817 was used in Flow cytometry/Cell sorting to study the effect of A proliferation-inducing ligand and B cell activation factor plasma concentrations on the inflammatory responses associated with malaria infection.
Fri Jun 01 00:00:00 EDT 2018
Targeting CD8(+) T cells prevents psoriasis development.
The Journal of allergy and clinical immunology
Di Meglio P,Villanova F,Navarini AA,Mylonas A,Tosi I,Nestle FO,Conrad C
MHCD0817 was used in flow cytometry to Targeting CD8(+) T cells prevents psoriasis development
Fri Jul 01 00:00:00 EDT 2016
Activation of Innate and Adaptive Immunity by a Recombinant Human Cytomegalovirus Strain Expressing an NKG2D Ligand.
PLoS pathogens
Tomić A,Varanasi PR,Golemac M,Malić S,Riese P,Borst EM,Mischak-Weissinger E,Guzmán CA,Krmpotić A,Jonjić S,Messerle M
MHCD0817 was used in Flow cytometry/Cell sorting to investigate a strategy for an HCMV vaccine that aims at the simultaneous activation of innate and adaptive immune responses.
Thu Dec 01 00:00:00 EST 2016
Statin modulation of monocyte phenotype and function: implications for HIV-1-associated neurocognitive disorders.
Journal of neurovirology
Yadav A,Betts MR,Collman RG
MHCD0817 was used in flow cytometry to assess if statins modulate the monocyte phenotype and function associated with HIV-1 neuropathogenesis
Sat Oct 01 00:00:00 EDT 2016
Predictive value of human cytomegalovirus (HCMV) T-cell response in the control of HCMV infection by seropositive solid-organ transplant recipients according to different assays and stimuli.
The new microbiologica
Gabanti E,Bruno F,Scaramuzzi L,Mangione F,Zelini P,Gerna G,Lilleri D
MHCD0817 was used in flow cytometry to evaluate the predictive values of the protective T-cell response for human cytomegalovirus disease
Sat Oct 01 00:00:00 EDT 2016
Plasmacytoid dendritic cells promote HIV-1-induced group 3 innate lymphoid cell depletion.
The Journal of clinical investigation
Zhang Z,Cheng L,Zhao J,Li G,Zhang L,Chen W,Nie W,Reszka-Blanco NJ,Wang FS,Su L
Published figure using CD8 monoclonal antibody (Product # MHCD0817) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Critical Role for the Adenosine Pathway in Controlling Simian Immunodeficiency Virus-Related Immune Activation and Inflammation in Gut Mucosal Tissues.
Journal of virology
He T,Brocca-Cofano E,Gillespie DG,Xu C,Stock JL,Ma D,Policicchio BB,Raehtz KD,Rinaldo CR,Apetrei C,Jackson EK,Macatangay BJ,Pandrea I
MHCD0817 was used in flow cytometry to elucidate the role of the adenosine pathway in human immunodeficiency virus type 1/simian immunodeficiency virus infection
Tue Sep 01 00:00:00 EDT 2015
Comparable Genital Tract Infection, Pathology, and Immunity in Rhesus Macaques Inoculated with Wild-Type or Plasmid-Deficient Chlamydia trachomatis Serovar D.
Infection and immunity
Qu Y,Frazer LC,O'Connell CM,Tarantal AF,Andrews CW,O'Connor SL,Russell AN,Sullivan JE,Poston TB,Vallejo AN,Darville T
MHCD0817 was used in Flow cytometry/Cell sorting to assess the potential for plasmid-deficient Chlamydia trachomatis to serve as a live attenuated vaccine in the genital tract.
Thu Oct 01 00:00:00 EDT 2015
Plasmacytoid dendritic cells suppress HIV-1 replication but contribute to HIV-1 induced immunopathogenesis in humanized mice.
PLoS pathogens
Li G,Cheng M,Nunoya J,Cheng L,Guo H,Yu H,Liu YJ,Su L,Zhang L
Published figure using CD8 monoclonal antibody (Product # MHCD0817) in Flow Cytometry
Tue Jul 01 00:00:00 EDT 2014
Treatment of SIV-infected sooty mangabeys with a type-I IFN agonist results in decreased virus replication without inducing hyperimmune activation.
Blood
Vanderford TH,Slichter C,Rogers KA,Lawson BO,Obaede R,Else J,Villinger F,Bosinger SE,Silvestri G
MHCD0817 was used in flow cytometry to test if low levels of IFN-I signaling prevent chronic immune activation and disease progression in SIV-infected sooty mangabeys
Thu Jun 14 00:00:00 EDT 2012
CCR5 blockade is well tolerated and induces changes in the tissue distribution of CCR5+ and CD25+ T cells in healthy, SIV-uninfected rhesus macaques.
Journal of medical primatology
Taaffe JE,Bosinger SE,Del Prete GQ,Else JG,Ratcliffe S,Ward CD,Migone T,Paiardini M,Silvestri G
MHCD0817 was used in flow cytometry to test if CCR5 signaling suppression reduces HIV-associated chronic immune activation
Wed Feb 01 00:00:00 EST 2012
Efficient infection, activation, and impairment of pDCs in the BM and peripheral lymphoid organs during early HIV-1 infection in humanized rag2⁻/⁻γ C⁻/⁻ mice in vivo.
Blood
Zhang L,Jiang Q,Li G,Jeffrey J,Kovalev GI,Su L
MHCD0817 was used in flow cytometry to study the relationship between plasmacytoid dendritic cells and HIV-1 pathogenesis
Thu Jun 09 00:00:00 EDT 2011
Simian immunodeficiency virus infection in rhesus macaques induces selective tissue specific B cell defects in double positive CD21+CD27+ memory B cells.
Clinical immunology (Orlando, Fla.)
Das A,Veazey RS,Wang X,Lackner AA,Xu H,Pahar B
MHCD0817 was used in flow cytometry to investigate memory B cell proliferation during SIV infection.
Thu Sep 01 00:00:00 EDT 2011
Distinct expression patterns of CD69 in mucosal and systemic lymphoid tissues in primary SIV infection of rhesus macaques.
PloS one
Wang X,Xu H,Alvarez X,Pahar B,Moroney-Rasmussen T,Lackner AA,Veazey RS
MHCD0817 was used in flow cytometry to compare CD69 expression on T cells from the intestine, spleen, lymph nodes, and blood of normal and SIV-infected macaques
Tue Apr 10 00:00:00 EDT 2012
Double-positive CD21+CD27+ B cells are highly proliferating memory cells and their distribution differs in mucosal and peripheral tissues.
PloS one
Das A,Xu H,Wang X,Yau CL,Veazey RS,Pahar B
MHCD0817 was used in flow cytometry to identify and characterize memory B cells in normal rhesus macaques.
Thu Jan 27 00:00:00 EST 2011
Effect of anti-IgE therapy on food allergen specific T cell responses in eosinophil associated gastrointestinal disorders.
Clinical and molecular allergy : CMA
Foster B,Foroughi S,Yin Y,Prussin C
MHCD0817 was used in flow cytometry to test if anti-IgE therapy attenuates allergen specific T helper 2 cell responses
Thu Apr 28 00:00:00 EDT 2011
Transcriptional reprogramming in nonhuman primate (rhesus macaque) tuberculosis granulomas.
PloS one
Mehra S,Pahar B,Dutta NK,Conerly CN,Philippi-Falkenstein K,Alvarez X,Kaushal D
MHCD0817 was used in flow cytometry to determine the gene expression profile of Mtb isolated from non-primate granuloma
Tue Aug 31 00:00:00 EDT 2010
Intestinal double-positive CD4+CD8+ T cells of neonatal rhesus macaques are proliferating, activated memory cells and primary targets for SIVMAC251 infection.
Blood
Wang X,Das A,Lackner AA,Veazey RS,Pahar B
Published figure using CD8 monoclonal antibody (Product # MHCD0817) in Flow Cytometry
Mon Dec 15 00:00:00 EST 2008
Single epitope mucosal vaccine delivered via immuno-stimulating complexes induces low level of immunity against simian-HIV.
Vaccine
Pahar B,Cantu MA,Zhao W,Kuroda MJ,Veazey RS,Montefiori DC,Clements JD,Aye PP,Lackner AA,Lovgren-Bengtsson K,Sestak K
MHCD0817 was used in flow cytometry to examine HIV/SIV-derived peptide vaccines.
Fri Nov 17 00:00:00 EST 2006
Peripheral immature CD2-/low T cell development from type 2 to type 1 cytokine production.
Journal of immunology (Baltimore, Md. : 1950)
Loza MJ,Perussia B
MHCD0817 was used in flow cytometry to identify and characterize immature CD2(-/low) T cells in peripheral blood.
Sun Sep 15 00:00:00 EDT 2002
