Product References
A single-cell map of dynamic chromatin landscapes of immune cells in renal cell carcinoma.
Nature cancer
Kourtis N,Wang Q,Wang B,Oswald E,Adler C,Cherravuru S,Malahias E,Zhang L,Golubov J,Wei Q,Lemus S,Ni M,Ding Y,Wei Y,Atwal GS,Thurston G,Macdonald LE,Murphy AJ,Dhanik A,Sleeman MA,Tykodi SS,Skokos D
Published figure using EOMES monoclonal antibody (Product # 14-4877-82) in Flow Cytometry
Fri Jul 01 00:00:00 EDT 2022
Transcriptional profiling of human Vδ1 T cells reveals a pathogen-driven adaptive differentiation program.
Cell reports
McMurray JL,von Borstel A,Taher TE,Syrimi E,Taylor GS,Sharif M,Rossjohn J,Remmerswaal EBM,Bemelman FJ,Vieira Braga FA,Chen X,Teichmann SA,Mohammed F,Berry AA,Lyke KE,Williamson KC,Stubbington MJT,Davey MS,Willcox CR,Willcox BE
Published figure using EOMES monoclonal antibody (Product # 14-4877-82) in Flow Cytometry
Tue May 24 00:00:00 EDT 2022
Unified rhombic lip origins of group 3 and group 4 medulloblastoma.
Nature
Smith KS,Bihannic L,Gudenas BL,Haldipur P,Tao R,Gao Q,Li Y,Aldinger KA,Iskusnykh IY,Chizhikov VV,Scoggins M,Zhang S,Edwards A,Deng M,Glass IA,Overman LM,Millman J,Sjoboen AH,Hadley J,Golser J,Mankad K,Sheppard H,Onar-Thomas A,Gajjar A,Robinson GW,Hovestadt V,Orr BA,Patay Z,Millen KJ,Northcott PA
14-4877-82 was used in Immunohistochemistry to find that the molecular and phenotypic features of clinically challenging medulloblastoma subgroups to their unified beginnings in the rhombic lip in the early stages of human development.
Thu Sep 01 00:00:00 EDT 2022
A cytotoxic-skewed immune set point predicts low neutralizing antibody levels after Zika virus infection.
Cell reports
McCarthy EE,Odorizzi PM,Lutz E,Smullin CP,Tenvooren I,Stone M,Simmons G,Hunt PW,Feeney ME,Norris PJ,Busch MP,Spitzer MH,Rutishauser RL
14-4877-82 was used in Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot to identify distinct cellular immune signatures during acute infection that reliably predict the persistence of high versus low ZIKV-specific neutralizing antibody levels 6 months after infection.
Tue May 17 00:00:00 EDT 2022
Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions.
Immunity
Schwabenland M,Salié H,Tanevski J,Killmer S,Lago MS,Schlaak AE,Mayer L,Matschke J,Püschel K,Fitzek A,Ondruschka B,Mei HE,Boettler T,Neumann-Haefelin C,Hofmann M,Breithaupt A,Genc N,Stadelmann C,Saez-Rodriguez J,Bronsert P,Knobeloch KP,Blank T,Thimme R,Glatzel M,Prinz M,Bengsch B
14-4877-82 was used in Mass cytometry to identify profound neuroinflammation with activation of innate and adaptive immune cells as correlates of COVID-19 neuropathology, with implications for potential therapeutic strategies.
Tue Jul 13 00:00:00 EDT 2021
Cell-type-specific effects of genetic variation on chromatin accessibility during human neuronal differentiation.
Nature neuroscience
Liang D,Elwell AL,Aygün N,Krupa O,Wolter JM,Kyere FA,Lafferty MJ,Cheek KE,Courtney KP,Yusupova M,Garrett ME,Ashley-Koch A,Crawford GE,Love MI,de la Torre-Ubieta L,Geschwind DH,Stein JL
14-4877-82 was used in Immunocytochemistry to model the functional impact of common genetic variation on the noncoding genome during human cortical development.
Thu Jul 01 00:00:00 EDT 2021
TBC1D3 promotes neural progenitor proliferation by suppressing the histone methyltransferase G9a.
Science advances
Hou QQ,Xiao Q,Sun XY,Ju XC,Luo ZG
14-4877-82 was used in Immunohistochemistry to demonstrate a mechanism underlying the role of a hominoid-specific gene in promoting cortical expansion.
Fri Jan 01 00:00:00 EST 2021
TBC1D3 promotes neural progenitor proliferation by suppressing the histone methyltransferase G9a.
Science advances
Hou QQ,Xiao Q,Sun XY,Ju XC,Luo ZG
14-4877-82 was used in Immunohistochemistry to demonstrate a mechanism underlying the role of a hominoid-specific gene in promoting cortical expansion.
Fri Jan 01 00:00:00 EST 2021
Culture, expansion, and flow-cytometry-based functional analysis of pteropid bat MR1-restricted unconventional T cells.
STAR protocols
Sia WR,Hey YY,Foo R,Wang LF,Leeansyah E
Published figure using EOMES monoclonal antibody (Product # 14-4877-82) in Flow Cytometry
Fri Jun 18 00:00:00 EDT 2021
Norovirus-Specific CD8+ T Cell Responses in Human Blood and Tissues.
Cellular and molecular gastroenterology and hepatology
Pattekar A,Mayer LS,Lau CW,Liu C,Palko O,Bewtra M,Consortium H,Lindesmith LC,Brewer-Jensen PD,Baric RS,Betts MR,Naji A,Wherry EJ,Tomov VT
Published figure using EOMES monoclonal antibody (Product # 14-4877-82) in Flow Cytometry
Tue Mar 08 00:00:00 EST 2022
Homeostatic Function and Inflammatory Activation of Ileal CD8+ Tissue-Resident T Cells Is Dependent on Mucosal Location.
Cellular and molecular gastroenterology and hepatology
Lutter L,Roosenboom B,Brand EC,Ter Linde JJ,Oldenburg B,van Lochem EG,Horjus Talabur Horje CS,van Wijk F
Published figure using EOMES monoclonal antibody (Product # 14-4877-82) in Flow Cytometry
Mon Mar 28 00:00:00 EDT 2022
Immune cell phenotypes associated with disease severity and long-term neutralizing antibody titers after natural dengue virus infection.
Cell reports. Medicine
Rouers A,Chng MHY,Lee B,Rajapakse MP,Kaur K,Toh YX,Sathiakumar D,Loy T,Thein TL,Lim VWX,Singhal A,Yeo TW,Leo YS,Vora KA,Casimiro D,Lim B,Tucker-Kellogg L,Rivino L,Newell EW,Fink K
14-4877-82 was used in Flow Cytometry to reveal associations between cellular profiles and disease severity, opening opportunities to study immunopathology in dengue disease and the potential predictive value of these parameters.
Tue May 18 00:00:00 EDT 2021
Cell-type-specific 3D epigenomes in the developing human cortex.
Nature
Song M,Pebworth MP,Yang X,Abnousi A,Fan C,Wen J,Rosen JD,Choudhary MNK,Cui X,Jones IR,Bergenholtz S,Eze UC,Juric I,Li B,Maliskova L,Lee J,Liu W,Pollen AA,Li Y,Wang T,Hu M,Kriegstein AR,Shen Y
Published figure using EOMES monoclonal antibody (Product # 14-4877-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2020
A Multiplex Human Pluripotent Stem Cell Platform Defines Molecular and Functional Subclasses of Autism-Related Genes.
Cell stem cell
Cederquist GY,Tchieu J,Callahan SJ,Ramnarine K,Ryan S,Zhang C,Rittenhouse C,Zeltner N,Chung SY,Zhou T,Chen S,Betel D,White RM,Tomishima M,Studer L
14-4877-82 was used in Immunocytochemistry to develop a multiplex human pluripotent stem cell platform for the purposes of testing early-developmental hypotheses of autism.
Thu Jul 02 00:00:00 EDT 2020
Complement opsonization of HIV affects primary infection of human colorectal mucosa and subsequent activation of T cells.
eLife
Bhattacharya P,Ellegård R,Khalid M,Svanberg C,Govender M,Keita ÅV,Söderholm JD,Myrelid P,Shankar EM,Nyström S,Larsson M
Published figure using EOMES monoclonal antibody (Product # 14-4877-82) in Flow Cytometry
Wed Sep 02 00:00:00 EDT 2020
The CD38/NAD/SIRTUIN1/EZH2 Axis Mitigates Cytotoxic CD8 T Cell Function and Identifies Patients with SLE Prone to Infections.
Cell reports
Katsuyama E,Suarez-Fueyo A,Bradley SJ,Mizui M,Marin AV,Mulki L,Krishfield S,Malavasi F,Yoon J,Sui SJH,Kyttaris VC,Tsokos GC
Published figure using EOMES monoclonal antibody (Product # 14-4877-82) in Flow Cytometry
Tue Jan 07 00:00:00 EST 2020
CD19-CAR-T Cells Bearing a KIR/PD-1-Based Inhibitory CAR Eradicate CD19+HLA-C1- Malignant B Cells While Sparing CD19+HLA-C1+ Healthy B Cells.
Cancers
Tao L,Farooq MA,Gao Y,Zhang L,Niu C,Ajmal I,Zhou Y,He C,Zhao G,Yao J,Liu M,Jiang W
Published figure using EOMES monoclonal antibody (Product # 14-4877-82) in Flow Cytometry
Sun Sep 13 00:00:00 EDT 2020
Single-cell transcriptome analysis reveals TOX as a promoting factor for T cell exhaustion and a predictor for anti-PD-1 responses in human cancer.
Genome medicine
Kim K,Park S,Park SY,Kim G,Park SM,Cho JW,Kim DH,Park YM,Koh YW,Kim HR,Ha SJ,Lee I
14-4877 was used in Flow cytometry/Cell sorting to identify the regulatory factors involved in tumor-infiltrating CD8+ T cell exhaustion by analyzing the scRNA-seq data.
Fri Feb 28 00:00:00 EST 2020
C reactive protein impairs adaptive immunity in immune cells of patients with melanoma.
Journal for immunotherapy of cancer
Yoshida T,Ichikawa J,Giuroiu I,Laino AS,Hao Y,Krogsgaard M,Vassallo M,Woods DM,Stephen Hodi F,Weber J
14-4877-82 was used in Flow Cytometry to investigate how CRP impacts the function of T cells and dendritic cells (DCs) from patients with melanoma.
Wed Apr 01 00:00:00 EDT 2020
C reactive protein impairs adaptive immunity in immune cells of patients with melanoma.
Journal for immunotherapy of cancer
Yoshida T,Ichikawa J,Giuroiu I,Laino AS,Hao Y,Krogsgaard M,Vassallo M,Woods DM,Stephen Hodi F,Weber J
14-4877-82 was used in Flow Cytometry to investigate how CRP impacts the function of T cells and dendritic cells (DCs) from patients with melanoma.
Wed Apr 01 00:00:00 EDT 2020
Intermediate progenitors support migration of neural stem cells into dentate gyrus outer neurogenic niches.
eLife
Nelson BR,Hodge RD,Daza RA,Tripathi PP,Arnold SJ,Millen KJ,Hevner RF
14-4877 was used in Immunohistochemistry to show that intermediate progenitors interact with mitotic and migrating NSCs throughout all stages of DG development.
Fri Apr 03 00:00:00 EDT 2020
Exploration of T-Cell Diversity Using Mass Cytometry.
Methods in molecular biology (Clifton, N.J.)
O'Boyle KC,Ohtani T,Manne S,Bengsch B,Henrickson SE,Wherry EJ,Alanio C
14-4877-82 was used in Miscellaneous, Immunohistochemistry (Paraffin), Western Blot to provide R scripts that contain a detailed workflow for initial evaluation of high-dimensional data generated from cohorts of patients.
Tue Jan 26 00:00:00 EST 2021
The TLR9 ligand CpG ODN 2006 is a poor adjuvant for the induction of de novo CD8+ T-cell responses in vitro.
Scientific reports
Papagno L,Kuse N,Lissina A,Gostick E,Price DA,Appay V,Nicoli F
Published figure using EOMES monoclonal antibody (Product # 14-4877-82) in Flow Cytometry
Wed Jul 15 00:00:00 EDT 2020
Multimodal Single-Cell Analysis Reveals Physiological Maturation in the Developing Human Neocortex.
Neuron
Mayer S,Chen J,Velmeshev D,Mayer A,Eze UC,Bhaduri A,Cunha CE,Jung D,Arjun A,Li E,Alvarado B,Wang S,Lovegren N,Gonzales ML,Szpankowski L,Leyrat A,West JAA,Panagiotakos G,Alvarez-Buylla A,Paredes MF,Nowakowski TJ,Pollen AA,Kriegstein AR
14-4877 was used in Immunohistochemistry to show highly specific neurotransmitter signaling during neurogenesis in the developing human neocortex and highlight evolutionarily divergent mechanisms of physiological signaling.
Wed Apr 03 00:00:00 EDT 2019
Immune Checkpoint Inhibitor-induced Reinvigoration of Tumor-infiltrating CD8+ T Cells is Determined by Their Differentiation Status in Glioblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research
Park J,Kwon M,Kim KH,Kim TS,Hong SH,Kim CG,Kang SG,Moon JH,Kim EH,Park SH,Chang JH,Shin EC
14-4877 was used in Flow cytometry/Cell sorting to examine the differentiation status of CD8+ tumor-infiltrating lymphocytes (TIL) from patients with primary GBM and their reinvigoration by ICIs to understand the nature of T-cell exhaustion in GBM.
Mon Apr 15 00:00:00 EDT 2019
Unique transcriptional and protein-expression signature in human lung tissue-resident NK cells.
Nature communications
Marquardt N,Kekäläinen E,Chen P,Lourda M,Wilson JN,Scharenberg M,Bergman P,Al-Ameri M,Hård J,Mold JE,Ljunggren HG,Michaëlsson J
Published figure using EOMES monoclonal antibody (Product # 14-4877-82) in Flow Cytometry
Mon Aug 26 00:00:00 EDT 2019
Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine.
Nature communications
Sagebiel AF,Steinert F,Lunemann S,Körner C,Schreurs RRCE,Altfeld M,Perez D,Reinshagen K,Bunders MJ
Published figure using EOMES monoclonal antibody (Product # 14-4877-82) in Flow Cytometry
Thu Feb 28 00:00:00 EST 2019
Molecular Signatures of a TLR4 Agonist-Adjuvanted HIV-1 Vaccine Candidate in Humans.
Frontiers in immunology
Anderson J,Olafsdottir TA,Kratochvil S,McKay PF,Östensson M,Persson J,Shattock RJ,Harandi AM
14-4877 was used in Flow cytometry/Cell sorting to investigate early transcriptional signatures induced in whole blood of healthy subjects following vaccination with a recombinant HIV-1 envelope glycoprotein subunit CN54gp140 adjuvanted with the TLR4 agonist glucopyranosyl lipid adjuvant-aqueous formulation.
Thu Mar 21 00:00:00 EDT 2019
TCF1 expression marks self-renewing human CD8+ T cells.
Blood advances
Kratchmarov R,Magun AM,Reiner SL
14-4877 was used in Flow cytometry/Cell sorting to show analyses of TCF1 expression from patient specimens may become a useful biomarker for adaptive immune function in response to vaccination, infection, autoimmunity, and cancer.
Tue Jul 24 00:00:00 EDT 2018
Long-term outcomes of a phase I study of agonist CD40 antibody and CTLA-4 blockade in patients with metastatic melanoma.
Oncoimmunology
Bajor DL,Mick R,Riese MJ,Huang AC,Sullivan B,Richman LP,Torigian DA,George SM,Stelekati E,Chen F,Melenhorst JJ,Lacey SF,Xu X,Wherry EJ,Gangadhar TC,Amaravadi RK,Schuchter LM,Vonderheide RH
14-4877 was used in Flow cytometry/Cell sorting to report long-term clinical outcomes and immune responses observed from a phase 1 trial of agonist CD40 monoclonal antibody and blocking CTLA-4 mAb in patients with metastatic melanoma.
Tue Jan 12 00:00:00 EST 2021
GSK3 Inhibition Drives Maturation of NK Cells and Enhances Their Antitumor Activity.
Cancer research
Cichocki F,Valamehr B,Bjordahl R,Zhang B,Rezner B,Rogers P,Gaidarova S,Moreno S,Tuininga K,Dougherty P,McCullar V,Howard P,Sarhan D,Taras E,Schlums H,Abbot S,Shoemaker D,Bryceson YT,Blazar BR,Wolchko S,Cooley S,Miller JS
14-4877 was used in Flow cytometry/Cell sorting to determine the role of GSK3 in the maturation of human natural killer cells.
Sun Oct 15 00:00:00 EDT 2017
Cytokine-mediated activation of human ex vivo-expanded Vγ9Vδ2 T cells.
Oncotarget
Domae E,Hirai Y,Ikeo T,Goda S,Shimizu Y
14-4877 was used in Flow cytometry/Cell sorting to show that interleukin (IL) -12 and IL-18 synergize to activate human ex vivo-expanded Vγ9Vδ2 T cells.
Tue Jul 11 00:00:00 EDT 2017
Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals.
Scientific reports
Tauriainen J,Scharf L,Frederiksen J,Naji A,Ljunggren HG,Sönnerborg A,Lund O,Reyes-Terán G,Hecht FM,Deeks SG,Betts MR,Buggert M,Karlsson AC
14487782 was used in flow cytometry to show T cell immunoglobulin and ITIM domain expression increases over time despite early initiation of antiretroviral treatment
Fri Jan 13 00:00:00 EST 2017
Fixed single-cell transcriptomic characterization of human radial glial diversity.
Nature methods
Thomsen ER,Mich JK,Yao Z,Hodge RD,Doyle AM,Jang S,Shehata SI,Nelson AM,Shapovalova NV,Levi BP,Ramanathan S
14487782 was used in flow cytometry to design Fixed and Recovered Intact Single-cell RNA (FRISCR), a method for profiling the transcriptomes of individual fixed, stained and sorted cells
Fri Jan 01 00:00:00 EST 2016
CD39 Expression Identifies Terminally Exhausted CD8+ T Cells.
PLoS pathogens
Gupta PK,Godec J,Wolski D,Adland E,Yates K,Pauken KE,Cosgrove C,Ledderose C,Junger WG,Robson SC,Wherry EJ,Alter G,Goulder PJ,Klenerman P,Sharpe AH,Lauer GM,Haining WN
14-4877 was used in Flow cytometry/Cell sorting to compare the expression of CD39 by CD8+ T cells from healthy donors and subjects with chronic viral infections.
Thu Oct 01 00:00:00 EDT 2015
