Product References
Perinatal murine cytomegalovirus infection reshapes the transcriptional profile and functionality of NK cells.
Nature communications
Rožmanić C,Lisnić B,Pribanić Matešić M,Mihalić A,Hiršl L,Park E,Lesac Brizić A,Indenbirken D,Viduka I,Šantić M,Adler B,Yokoyama WM,Krmpotić A,Juranić Lisnić V,Jonjić S,Brizić I
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Thu Oct 12 00:00:00 EDT 2023
The Potential of Dendritic-Cell-Based Vaccines to Modulate Type 3 Innate Lymphoid Cell Populations.
International journal of molecular sciences
Chan L,Mehrani Y,Minott JA,Bridle BW,Karimi K
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Thu Jan 26 00:00:00 EST 2023
GM-CSF-activated human dendritic cells promote type 1 T follicular helper cell polarization in a CD40-dependent manner.
Journal of cell science
Korniotis S,Saichi M,Trichot C,Hoffmann C,Amblard E,Viguier A,Grondin S,Noel F,Mattoo H,Soumelis V
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2022
Agr2-associated ER stress promotes adherent-invasive E. coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis.
Cell reports
Viladomiu M,Khounlotham M,Dogan B,Lima SF,Elsaadi A,Cardakli E,Castellanos JG,Ng C,Herzog J,Schoenborn AA,Ellermann M,Liu B,Zhang S,Gulati AS,Sartor RB,Simpson KW,Lipkin SM,Longman RS
50-5825-82 was used in Flow cytometry/Cell sorting to reveal a specific and reciprocal interaction of the expansion of the CD pathobiont AIEC with ER-stress-associated ileocolitis and highlight a distinct cellular mechanism for IL-23-dependent ileocolitis.
Tue Nov 15 00:00:00 EST 2022
Agr2-associated ER stress promotes adherent-invasive E. coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis.
Cell reports
Viladomiu M,Khounlotham M,Dogan B,Lima SF,Elsaadi A,Cardakli E,Castellanos JG,Ng C,Herzog J,Schoenborn AA,Ellermann M,Liu B,Zhang S,Gulati AS,Sartor RB,Simpson KW,Lipkin SM,Longman RS
50-5825-82 was used in Flow cytometry/Cell sorting to reveal a specific and reciprocal interaction of the expansion of the CD pathobiont AIEC with ER-stress-associated ileocolitis and highlight a distinct cellular mechanism for IL-23-dependent ileocolitis.
Tue Nov 15 00:00:00 EST 2022
Development of Tbet- and CD11c-expressing B cells in a viral infection requires T follicular helper cells outside of germinal centers.
Immunity
Song W,Antao OQ,Condiff E,Sanchez GM,Chernova I,Zembrzuski K,Steach H,Rubtsova K,Angeletti D,Lemenze A,Laidlaw BJ,Craft J,Weinstein JS
50-5825-82 was used in Flow Cytometry to conclude that Tbet+CD11c+ B cells comprise a GC-independent memory subset capable of rapid and robust recall responses.
Tue Feb 08 00:00:00 EST 2022
Multi-tissue single-cell analysis deconstructs the complex programs of mouse natural killer and type 1 innate lymphoid cells in tissues and circulation.
Immunity
McFarland AP,Yalin A,Wang SY,Cortez VS,Landsberger T,Sudan R,Peng V,Miller HL,Ricci B,David E,Faccio R,Amit I,Colonna M
50-5825-82 was used in Flow cytometry/Cell sorting to identify gene expression programs of tissue-specific ILC1s, tissue-specific NK cells, and non-tissue-specific populations in blood, spleen, and other tissues largely corresponding to circulating cells.
Tue Jun 08 00:00:00 EDT 2021
Adherent-invasive E. coli metabolism of propanediol in Crohn's disease regulates phagocytes to drive intestinal inflammation.
Cell host & microbe
Viladomiu M,Metz ML,Lima SF,Jin WB,Chou L,Guo CJ,Diehl GE,Simpson KW,Scherl EJ,Longman RS
50-5825-82 was used in flow cytometry to identify MNPs as metabolic sensors linking AIEC metabolism with intestinal inflammation and identify microbial metabolism as a potential therapeutic target in Crohn's disease treatment.
Wed Apr 14 00:00:00 EDT 2021
Adherent-invasive E. coli metabolism of propanediol in Crohn's disease regulates phagocytes to drive intestinal inflammation.
Cell host & microbe
Viladomiu M,Metz ML,Lima SF,Jin WB,Chou L,Guo CJ,Diehl GE,Simpson KW,Scherl EJ,Longman RS
50-5825-82 was used in flow cytometry to identify MNPs as metabolic sensors linking AIEC metabolism with intestinal inflammation and identify microbial metabolism as a potential therapeutic target in Crohn's disease treatment.
Wed Apr 14 00:00:00 EDT 2021
ADAM12 is a costimulatory molecule that determines Th1 cell fate and mediates tissue inflammation.
Cellular & molecular immunology
Liu Y,Bockermann R,Hadi M,Safari I,Carrion B,Kveiborg M,Issazadeh-Navikas S
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Sun Aug 01 00:00:00 EDT 2021
Imbalance between T helper 1 and regulatory T cells plays a detrimental role in experimental Parkinson's disease in mice.
The Journal of international medical research
Li W,Luo Y,Xu H,Ma Q,Yao Q
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection.
Nature communications
Zhao Z,Wang H,Shi M,Zhu T,Pediongco T,Lim XY,Meehan BS,Nelson AG,Fairlie DP,Mak JYW,Eckle SBG,de Lima Moreira M,Tumpach C,Bramhall M,Williams CG,Lee HJ,Haque A,Evrard M,Rossjohn J,McCluskey J,Corbett AJ,Chen Z
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Fri Jul 16 00:00:00 EDT 2021
Heterologous arenavirus vector prime-boost overrules self-tolerance for efficient tumor-specific CD8 T cell attack.
Cell reports. Medicine
Bonilla WV,Kirchhammer N,Marx AF,Kallert SM,Krzyzaniak MA,Lu M,Darbre S,Schmidt S,Raguz J,Berka U,Vincenti I,Pauzuolis M,Kerber R,Hoepner S,Günther S,Magnus C,Merkler D,Orlinger KK,Zippelius A,Pinschewer DD
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Tue Mar 16 00:00:00 EDT 2021
Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma.
Cell reports
Budhu S,Giese R,Gupta A,Fitzgerald K,Zappasodi R,Schad S,Hirschhorn D,Campesato LF,De Henau O,Gigoux M,Liu C,Mazo G,Deng L,Barker CA,Wolchok JD,Merghoub T
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Culture, expansion, and flow-cytometry-based functional analysis of pteropid bat MR1-restricted unconventional T cells.
STAR protocols
Sia WR,Hey YY,Foo R,Wang LF,Leeansyah E
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Fri Jun 18 00:00:00 EDT 2021
Role of nuclear localization in the regulation and function of T-bet and Eomes in exhausted CD8 T cells.
Cell reports
McLane LM,Ngiow SF,Chen Z,Attanasio J,Manne S,Ruthel G,Wu JE,Staupe RP,Xu W,Amaravadi RK,Xu X,Karakousis GC,Mitchell TC,Schuchter LM,Huang AC,Freedman BD,Betts MR,Wherry EJ
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Immunocytochemistry
Tue May 11 00:00:00 EDT 2021
C-Reactive Protein Suppresses the Th17 Response Indirectly by Attenuating the Antigen Presentation Ability of Monocyte Derived Dendritic Cells in Experimental Autoimmune Encephalomyelitis.
Frontiers in immunology
Shen ZY,Zheng Y,Pecsok MK,Wang K,Li W,Gong MJ,Wu F,Zhang L
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Western Blot
Thu Jul 01 00:00:00 EDT 2021
Graded RhoA GTPase Expression in Treg Cells Distinguishes Tumor Immunity From Autoimmunity.
Frontiers in immunology
Kalim KW,Yang JQ,Modur V,Nguyen P,Li Y,Zheng Y,Guo F
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Tue Jan 11 00:00:00 EST 2022
CD4+ effector T cells accelerate Alzheimer's disease in mice.
Journal of neuroinflammation
Machhi J,Yeapuri P,Lu Y,Foster E,Chikhale R,Herskovitz J,Namminga KL,Olson KE,Abdelmoaty MM,Gao J,Quadros RM,Kiyota T,Jingjing L,Kevadiya BD,Wang X,Liu Y,Poluektova LY,Gurumurthy CB,Mosley RL,Gendelman HE
50-5825-82 was used in Flow Cytometry to investigate the role of effector immunity and how it could affect cellular-level disease pathobiology in an alzheimer's disease animal model.
Fri Nov 19 00:00:00 EST 2021
Lymph node-resident dendritic cells drive TH2 cell development involving MARCH1.
Science immunology
Castellanos CA,Ren X,Gonzalez SL,Li HK,Schroeder AW,Liang HE,Laidlaw BJ,Hu D,Mak ACY,Eng C,Rodríguez-Santana JR,LeNoir M,Yan Q,Celedón JC,Burchard EG,Zamvil SS,Ishido S,Locksley RM,Cyster JG,Huang X,Shin JS
50-5825-82 was used in Flow cytometry/Cell sorting to suggest that TH2 cell development depends on ubiquitin-mediated clearance of antigen-presenting and costimulatory molecules by LN-resident DCs and consequent control of TCR signaling.
Fri Oct 15 00:00:00 EDT 2021
Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy.
Immunity
Milner JJ,Toma C,He Z,Kurd NS,Nguyen QP,McDonald B,Quezada L,Widjaja CE,Witherden DA,Crowl JT,Shaw LA,Yeo GW,Chang JT,Omilusik KD,Goldrath AW
50-5825 was used in Flow cytometry/Cell sorting to identify discrete lineages of intestinal antigen-specific CD8+ T cells, including a Blimp1hiId3lo tissue-resident effector cell population most prominent in the early phase of acute viral and bacterial infections and a molecularly distinct Blimp1loId3hi tissue-resident memory population that subsequently accumulated at later infection time points.
Tue May 19 00:00:00 EDT 2020
Antigen discovery unveils resident memory and migratory cell roles in antifungal resistance.
Mucosal immunology
Dobson HE,Dias LDS,Kohn EM,Fites S,Wiesner DL,Dileepan T,Kujoth GC,Abraham A,Ostroff GR,Klein BS,Wüthrich M
50-5825 was used in Flow cytometry/Cell sorting to report the identification of a novel fungal antigen that we harnessed for mucosal vaccination and tetramer generation to test whether we can elicit protective, antigen-specific tissue-resident memory (Trm) CD4+ T cells in the lung parenchyma.
Fri May 01 00:00:00 EDT 2020
MiR-1165-3p Suppresses Th2 Differentiation via Targeting IL-13 and PPM1A in a Mouse Model of Allergic Airway Inflammation.
Allergy, asthma & immunology research
Wang Z,Ji N,Chen Z,Sun Z,Wu C,Yu W,Hu F,Huang M,Zhang M
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2020
Ribosome profiling unveils translational regulation of metabolic enzymes in primary CD4+ Th1 cells.
Developmental and comparative immunology
Manfrini N,Ricciardi S,Alfieri R,Ventura G,Calamita P,Favalli A,Biffo S
50-5825 was used in Flow cytometry/Cell sorting to show that translation regulates the metabolic asset of effector T cells.
Sat Aug 01 00:00:00 EDT 2020
CD19-CAR-T Cells Bearing a KIR/PD-1-Based Inhibitory CAR Eradicate CD19+HLA-C1- Malignant B Cells While Sparing CD19+HLA-C1+ Healthy B Cells.
Cancers
Tao L,Farooq MA,Gao Y,Zhang L,Niu C,Ajmal I,Zhou Y,He C,Zhao G,Yao J,Liu M,Jiang W
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Sun Sep 13 00:00:00 EDT 2020
Programming Multifaceted Pulmonary T Cell Immunity by Combination Adjuvants.
Cell reports. Medicine
Marinaik CB,Kingstad-Bakke B,Lee W,Hatta M,Sonsalla M,Larsen A,Neldner B,Gasper DJ,Kedl RM,Kawaoka Y,Suresh M
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Tue Sep 22 00:00:00 EDT 2020
Th2 Biased Immunity With Altered B Cell Profiles in Circulation of Patients With Sporotrichosis Caused by Sporothrix globosa.
Frontiers in immunology
Zu J,Yao L,Song Y,Cui Y,Guan M,Chen R,Zhen Y,Li S
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Mon May 31 00:00:00 EDT 2021
Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells.
Nature communications
Lucas B,White AJ,Cosway EJ,Parnell SM,James KD,Jones ND,Ohigashi I,Takahama Y,Jenkinson WE,Anderson G
50-5825 was used in Flow cytometry/Cell sorting to study the mechanism that controls the development of αβ T cell lineages in the thymus.
Mon May 04 00:00:00 EDT 2020
Inhibition of EZH2 ameliorates bacteria-induced liver injury by repressing RUNX1 in dendritic cells.
Cell death & disease
Wang Y,Wang Q,Wang B,Gu Y,Yu H,Yang W,Ren X,Qian F,Zhao X,Xiao Y,Zhang Y,Jin M,Zhu M
50-5825 was used in Flow cytometry/Cell sorting to show enhancer of zeste homolog 2 can mediate anti-inflammatory effects by inhibiting RUNX1 in dendritic cells.
Tue Dec 01 00:00:00 EST 2020
Adjuvant-free nanofiber vaccine induces in situ lung dendritic cell activation and TH17 responses.
Science advances
Si Y,Tian Q,Zhao F,Kelly SH,Shores LS,Camacho DF,Sperling AI,Andrade MS,Collier JH,Chong AS
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2020
B cells induced by Schistosoma japonicum infection display diverse regulatory phenotypes and modulate CD4+ T cell response.
Parasites & vectors
Xiao J,Guan F,Sun L,Zhang Y,Zhang X,Lu S,Liu W
50-5825-82 was used in Flow Cytometry to show that Schistosoma japonicum infection modulates the differentiation of B cell subsets that have the capability to affect the CD4+ T cell response.
Fri Mar 20 00:00:00 EDT 2020
Polychromic Reporter Mice Reveal Unappreciated Innate Lymphoid Cell Progenitor Heterogeneity and Elusive ILC3 Progenitors in Bone Marrow.
Immunity
Walker JA,Clark PA,Crisp A,Barlow JL,Szeto A,Ferreira ACF,Rana BMJ,Jolin HE,Rodriguez-Rodriguez N,Sivasubramaniam M,Pannell R,Cruickshank J,Daly M,Haim-Vilmovsky L,Teichmann SA,McKenzie ANJ
50-5825 was used in Flow cytometry/Cell sorting to identify a discrete ILC2-committed population and delineated transition states between early progenitors and a highly heterogeneous ILC1, ILC3, and NK precursor cell cluster.
Tue Jul 16 00:00:00 EDT 2019
FCRL5+ Memory B Cells Exhibit Robust Recall Responses.
Cell reports
Kim CC,Baccarella AM,Bayat A,Pepper M,Fontana MF
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Tue Apr 30 00:00:00 EDT 2019
Keap1-Nrf2 System Plays an Important Role in Invariant Natural Killer T Cell Development and Homeostasis.
Cell reports
Pyaram K,Kumar A,Kim YH,Noel S,Reddy SP,Rabb H,Chang CH
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Tue Apr 16 00:00:00 EDT 2019
Single-Cell Profiling Defines Transcriptomic Signatures Specific to Tumor-Reactive versus Virus-Responsive CD4+ T Cells.
Cell reports
Magen A,Nie J,Ciucci T,Tamoutounour S,Zhao Y,Mehta M,Tran B,McGavern DB,Hannenhalli S,Bosselut R
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Tue Dec 03 00:00:00 EST 2019
The Obese Liver Environment Mediates Conversion of NK Cells to a Less Cytotoxic ILC1-Like Phenotype.
Frontiers in immunology
Cuff AO,Sillito F,Dertschnig S,Hall A,Luong TV,Chakraverty R,Male V
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Wed Oct 21 00:00:00 EDT 2020
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
TRPM2 Exacerbates Central Nervous System Inflammation in Experimental Autoimmune Encephalomyelitis by Increasing Production of CXCL2 Chemokines.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Tsutsui M,Hirase R,Miyamura S,Nagayasu K,Nakagawa T,Mori Y,Shirakawa H,Kaneko S
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Wed Sep 26 00:00:00 EDT 2018
PDL-1 Blockade Prevents T Cell Exhaustion, Inhibits Autophagy, and Promotes Clearance of Leishmania donovani.
Infection and immunity
Habib S,El Andaloussi A,Elmasry K,Handoussa A,Azab M,Elsawey A,Al-Hendy A,Ismail N
50-5825 was used in Flow cytometry/Cell sorting to examine the role of PD1/PDL-1 in the pathogenesis of visceral leishmaniasis.
Fri Jun 01 00:00:00 EDT 2018
Regulation of chitinase-3-like-1 in T cell elicits Th1 and cytotoxic responses to inhibit lung metastasis.
Nature communications
Kim DH,Park HJ,Lim S,Koo JH,Lee HG,Choi JO,Oh JH,Ha SJ,Kang MJ,Lee CM,Lee CG,Elias JA,Choi JM
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Mon Feb 05 00:00:00 EST 2018
The Combination Therapy of Dietary Galacto-Oligosaccharides With Budesonide Reduces Pulmonary Th2 Driving Mediators and Mast Cell Degranulation in a Murine Model of House Dust Mite Induced Asthma.
Frontiers in immunology
Verheijden KAT,Braber S,Leusink-Muis T,Jeurink PV,Thijssen S,Kraneveld AD,Garssen J,Folkerts G,Willemsen LEM
50-5825 was used in Flow cytometry/Cell sorting to compare the efficacy of budesonide or different doses of galacto-oligosaccharides alone or with a combination therapy of budesonide and galacto-oligosaccharides on house dust mite-allergic responses in mice.
Mon Sep 30 00:00:00 EDT 2019
Regulatory T Cells Promote Myositis and Muscle Damage in Toxoplasma gondii Infection.
Journal of immunology (Baltimore, Md. : 1950)
Jin RM,Blair SJ,Warunek J,Heffner RR,Blader IJ,Wohlfert EA
50-5825 was used in Flow cytometry/Cell sorting to study how the tissue environment established by Toxoplasma gondii leads to a pathogenic role for regulatory T cells.
Sun Jan 01 00:00:00 EST 2017
Huai Qi Huang corrects the balance of Th1/Th2 and Treg/Th17 in an ovalbumin-induced asthma mouse model.
Bioscience reports
Liang P,Peng S,Zhang M,Ma Y,Zhen X,Li H
50-5825 was used in Flow cytometry/Cell sorting to determine the immunoregulatory effects of Huai Qi Huang on regulatory and helper T cell balance in ovalbumin induced asthma.
Fri Dec 22 00:00:00 EST 2017
Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APPSWE/PS1ΔE9 murine model of Alzheimer's disease.
Scientific reports
Minter MR,Hinterleitner R,Meisel M,Zhang C,Leone V,Zhang X,Oyler-Castrillo P,Zhang X,Musch MW,Shen X,Jabri B,Chang EB,Tanzi RE,Sisodia SS
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Tue Sep 05 00:00:00 EDT 2017
Conventional NK cells and ILC1 are partially ablated in the livers of Ncr1 iCreTbx21 fl/fl mice.
Wellcome open research
Cuff AO,Male V
Sat Jan 09 00:00:00 EST 2021
Resistance to TGFβ suppression and improved anti-tumor responses in CD8+ T cells lacking PTPN22.
Nature communications
Brownlie RJ,Garcia C,Ravasz M,Zehn D,Salmond RJ,Zamoyska R
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Tue Nov 07 00:00:00 EST 2017
Eomesodermin and T-bet mark developmentally distinct human natural killer cells.
JCI insight
Collins A,Rothman N,Liu K,Reiner SL
50-5825 was used in Flow cytometry/Cell sorting to demonstrate the expression pattern of signature NK cell transcription factors during developmental maturation.
Thu Mar 09 00:00:00 EST 2017
Characterisation of innate lymphoid cell populations at different sites in mice with defective T cell immunity.
Wellcome open research
Dutton EE,Camelo A,Sleeman M,Herbst R,Carlesso G,Belz GT,Withers DR
50-5825 was used in Flow cytometry/Cell sorting to compare the innate lymphoid cell populations at different sites in mice with defective T cell immunity.
Sat Jan 09 00:00:00 EST 2021
Splenic CD4+ T Cells in Progressive Visceral Leishmaniasis Show a Mixed Effector-Regulatory Phenotype and Impair Macrophage Effector Function through Inhibitory Receptor Expression.
PloS one
Medina-Colorado AA,Osorio EY,Saldarriaga OA,Travi BL,Kong F,Spratt H,Soong L,Melby PC
50-5825 was used in Flow cytometry/Cell sorting to show the expression of counter-regulatory molecules on splenic CD4+ T cells and macrophages promotes a permissive macrophage phenotype, attenuating intracellular parasite control.
Mon Aug 07 00:00:00 EDT 2017
Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche.
Cell
Clever D,Roychoudhuri R,Constantinides MG,Askenase MH,Sukumar M,Klebanoff CA,Eil RL,Hickman HD,Yu Z,Pan JH,Palmer DC,Phan AT,Goulding J,Gattinoni L,Goldrath AW,Belkaid Y,Restifo NP
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Thu Aug 25 00:00:00 EDT 2016
The cytotoxic T cell proteome and its shaping by the kinase mTOR.
Nature immunology
Hukelmann JL,Anderson KE,Sinclair LV,Grzes KM,Murillo AB,Hawkins PT,Stephens LR,Lamond AI,Cantrell DA
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Western Blot
Fri Jan 01 00:00:00 EST 2016
B-cell anergy induces a Th17 shift in a novel B lymphocyte transgenic NOD mouse model, the 116C-NOD mouse.
European journal of immunology
Carrascal J,Carrillo J,Arpa B,Egia-Mendikute L,Rosell-Mases E,Pujol-Autonell I,Planas R,Mora C,Mauricio D,Ampudia RM,Vives-Pi M,Verdaguer J
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Characterization of Human CD8 T Cell Responses in Dengue Virus-Infected Patients from India.
Journal of virology
Chandele A,Sewatanon J,Gunisetty S,Singla M,Onlamoon N,Akondy RS,Kissick HT,Nayak K,Reddy ES,Kalam H,Kumar D,Verma A,Panda H,Wang S,Angkasekwinai N,Pattanapanyasat K,Chokephaibulkit K,Medigeshi GR,Lodha R,Kabra S,Ahmed R,Murali-Krishna K
50-5825 was used in Flow cytometry/Cell sorting to reveal that the vast majority of CD8 T cells from dengue patients become cytokine unresponsive due to TCR signalling deficiencies.
Thu Dec 15 00:00:00 EST 2016
Human Head and Neck Squamous Cell Carcinoma-Associated Semaphorin 4D Induces Expansion of Myeloid-Derived Suppressor Cells.
Journal of immunology (Baltimore, Md. : 1950)
Younis RH,Han KL,Webb TJ
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2016
ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation.
eLife
Pearson C,Thornton EE,McKenzie B,Schaupp AL,Huskens N,Griseri T,West N,Tung S,Seddon BP,Uhlig HH,Powrie F
50-5825 was used in Flow cytometry/Cell sorting to investigate how a small population of innate lymphoid cells (ILCs) has large effects on immune homeostasis, showing that ILC3s produce GM-CSF to orchestrate acute intestinal inflammation.
Mon Jan 18 00:00:00 EST 2016
The transduction pattern of IL-12-encoding lentiviral vectors shapes the immunological outcome.
European journal of immunology
Goyvaerts C,Broos K,Escors D,Heirman C,Raes G,De Baetselier P,Thielemans K,Breckpot K
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2015
Diverse roles for T-bet in the effector responses required for resistance to infection.
Journal of immunology (Baltimore, Md. : 1950)
Harms Pritchard G,Hall AO,Christian DA,Wagage S,Fang Q,Muallem G,John B,Glatman Zaretsky A,Dunn WG,Perrigoue J,Reiner SL,Hunter CA
50-5825 was used in Flow cytometry/Cell sorting to highlight T-bet-independent pathways to IFN-γ production and reveal a novel role for this transcription factor in coordinating the T cell responses necessary to control infection in peripheral tissues.
Sun Feb 01 00:00:00 EST 2015
Cutaneous Infection with Leishmania major Mediates Heterologous Protection against Visceral Infection with Leishmania infantum.
Journal of immunology (Baltimore, Md. : 1950)
Romano A,Doria NA,Mendez J,Sacks DL,Peters NC
50-5825 was used in Flow cytometry/Cell sorting to demonstrate that cutaneous infection with Leishmania major provides heterologous protection against visceral infection with Leishmania infantum.
Thu Oct 15 00:00:00 EDT 2015
Intranasal Administration of Lentiviral miR-135a Regulates Mast Cell and Allergen-Induced Inflammation by Targeting GATA-3.
PloS one
Deng YQ,Yang YQ,Wang SB,Li F,Liu MZ,Hua QQ,Tao ZZ
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Tue May 31 00:00:00 EDT 2016
IFN-γ and IL-21 Double Producing T Cells Are Bcl6-Independent and Survive into the Memory Phase in Plasmodium chabaudi Infection.
PloS one
Carpio VH,Opata MM,Montañez ME,Banerjee PP,Dent AL,Stephens R
50-5825 was used in Flow cytometry/Cell sorting to elucidate the lineage of a specific Ifng+ CD4 T cell subset generated during Plasmodium chabaudi infection in mice.
Sun Jun 26 00:00:00 EDT 2016
CD4CD8αα lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease.
PLoS biology
Sarrabayrouse G,Bossard C,Chauvin JM,Jarry A,Meurette G,Quévrain E,Bridonneau C,Preisser L,Asehnoune K,Labarrière N,Altare F,Sokol H,Jotereau F
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Tue Apr 01 00:00:00 EDT 2014
Nuclear role of WASp in gene transcription is uncoupled from its ARP2/3-dependent cytoplasmic role in actin polymerization.
Journal of immunology (Baltimore, Md. : 1950)
Sadhukhan S,Sarkar K,Taylor M,Candotti F,Vyas YM
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Tue Jul 01 00:00:00 EDT 2014
IFN-γ-producing and IL-17-producing γδ T cells differentiate at distinct developmental stages in murine fetal thymus.
Journal of immunology (Baltimore, Md. : 1950)
Shibata K,Yamada H,Nakamura M,Hatano S,Katsuragi Y,Kominami R,Yoshikai Y
50-5825 was used in Flow cytometry/Cell sorting to compare the functions of γδ T cells derived from double-negative 2 and double-negative 3 cells in the murine fetal thymus.
Sat Mar 01 00:00:00 EST 2014
Bhlhe40 controls cytokine production by T cells and is essential for pathogenicity in autoimmune neuroinflammation.
Nature communications
Lin CC,Bradstreet TR,Schwarzkopf EA,Sim J,Carrero JA,Chou C,Cook LE,Egawa T,Taneja R,Murphy TL,Russell JH,Edelson BT
50-5825 was used in Flow cytometry/Cell sorting to study the factors affecting pathogenicity of TH cells in experimental autoimmune encephalomyelitis (EAE), showing that Bhlhe40 controls cytokine production by T cells and is essential for pathogenicity in EAE.
Thu Apr 03 00:00:00 EDT 2014
Clonal analysis of the T-cell response to in vivo expressed Mycobacterium tuberculosis protein Rv2034, using a CD154 expression based T-cell cloning method.
PloS one
Commandeur S,Coppola M,Dijkman K,Friggen AH,van Meijgaarden KE,van den Eeden SJ,Wilson L,van der Ploeg-van Schip JJ,Franken KL,Geluk A,Ottenhoff TH
50-5825 was used in Flow cytometry/Cell sorting to identify T-cell subsets that likely play a significant role in controlling Mtb infection.
Fri Jan 08 00:00:00 EST 2016
Mesenchymal stem cells alleviate TNBS-induced colitis by modulating inflammatory and autoimmune responses.
World journal of gastroenterology
Chen QQ,Yan L,Wang CZ,Wang WH,Shi H,Su BB,Zeng QH,Du HT,Wan J
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Western Blot
Wed Aug 07 00:00:00 EDT 2013
Mitral and tufted cells are potential cellular targets of nitration in the olfactory bulb of aged mice.
PloS one
Yang MJ,Sim S,Jeon JH,Jeong E,Kim HC,Park YJ,Kim IB
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Immunohistochemistry
Tue Sep 17 00:00:00 EDT 2013
The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology.
Immunity
Hall AO,Beiting DP,Tato C,John B,Oldenhove G,Lombana CG,Pritchard GH,Silver JS,Bouladoux N,Stumhofer JS,Harris TH,Grainger J,Wojno ED,Wagage S,Roos DS,Scott P,Turka LA,Cherry S,Reiner SL,Cua D,Belkaid Y,Elloso MM,Hunter CA
50-5825 was used in Flow cytometry/Cell sorting to study the promotion of distinct Treg cell populations by the cytokines IL-27 and IFN-y, and the role they play in limiting infection induced pathology.
Fri Sep 21 00:00:00 EDT 2012
Distinct requirements for T-bet in gut innate lymphoid cells.
The Journal of experimental medicine
Sciumé G,Hirahara K,Takahashi H,Laurence A,Villarino AV,Singleton KL,Spencer SP,Wilhelm C,Poholek AC,Vahedi G,Kanno Y,Belkaid Y,O'Shea JJ
50-5825 was used in Flow cytometry/Cell sorting to determine whether the transcription factor T-bet can control the development and function of a distinct interleukin-22-producing innate lymphoid cell subset.
Mon Dec 17 00:00:00 EST 2012
CD134 plus CD137 dual costimulation induces Eomesodermin in CD4 T cells to program cytotoxic Th1 differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Qui HZ,Hagymasi AT,Bandyopadhyay S,St Rose MC,Ramanarasimhaiah R,Ménoret A,Mittler RS,Gordon SM,Reiner SL,Vella AT,Adler AJ
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Sat Oct 01 00:00:00 EDT 2011
Increase in Th17 and T-reg lymphocytes and decrease of IL22 correlate with the recovery phase of acute EAE in rat.
PloS one
Almolda B,Costa M,Montoya M,González B,Castellano B
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Mon Mar 26 00:00:00 EDT 2012
Cytokine requirements for the differentiation and expansion of IL-17A- and IL-22-producing human Vgamma2Vdelta2 T cells.
Journal of immunology (Baltimore, Md. : 1950)
Ness-Schwickerath KJ,Jin C,Morita CT
Published figure using T-bet monoclonal antibody (Product # 50-5825-82) in Flow Cytometry
Tue Jun 15 00:00:00 EDT 2010
