Product References
Suppression of preadipocyte determination by SOX4 limits white adipocyte hyperplasia in obesity.
iScience
He T,Wang S,Li S,Shen H,Hou L,Liu Y,Wei Y,Xie F,Zhang Z,Zhao Z,Mo C,Guo H,Huang Q,Zhang R,Shen D,Li B
12-5921-82 was used in Flow Cytometry to highlight the importance of SOX4 in regulating the adipocyte hyperplasia in obesity.
Fri Apr 21 00:00:00 EDT 2023
Heterochronic parabiosis reprograms the mouse brain transcriptome by shifting aging signatures in multiple cell types.
Nature aging
Ximerakis M,Holton KM,Giadone RM,Ozek C,Saxena M,Santiago S,Adiconis X,Dionne D,Nguyen L,Shah KM,Goldstein JM,Gasperini C,Gampierakis IA,Lipnick SL,Simmons SK,Buchanan SM,Wagers AJ,Regev A,Levin JZ,Rubin LL
12-5921-82 was used in Flow cytometry/Cell sorting to suggest new strategies for slowing deterioration and driving regeneration in the aging brain through approaches that do not rely on disease-specific mechanisms or actions of individual circulating factors.
Wed Mar 01 00:00:00 EST 2023
Hypoxia promotes osteogenesis by facilitating acetyl-CoA-mediated mitochondrial-nuclear communication.
The EMBO journal
Pouikli A,Maleszewska M,Parekh S,Yang M,Nikopoulou C,Bonfiglio JJ,Mylonas C,Sandoval T,Schumacher AL,Hinze Y,Matic I,Frezza C,Tessarz P
12-5921-82 was used in Flow Cytometry to study the impact of normoxia on mitochondrial-nuclear communication during stem cell differentiation.
Thu Dec 01 00:00:00 EST 2022
Integrative analysis of scRNA-seq and scATAC-seq revealed transit-amplifying thymic epithelial cells expressing autoimmune regulator.
eLife
Miyao T,Miyauchi M,Kelly ST,Terooatea TW,Ishikawa T,Oh E,Hirai S,Horie K,Takakura Y,Ohki H,Hayama M,Maruyama Y,Seki T,Ishii H,Yabukami H,Yoshida M,Inoue A,Sakaue-Sawano A,Miyawaki A,Muratani M,Minoda A,Akiyama N,Akiyama T
12-5921-82 was used in Flow cytometry/Cell sorting to provide evidence for the existence of transit-amplifying Aire+mTEC precursors during the Aire+mTEC differentiation process of the postnatal thymus.
Tue May 17 00:00:00 EDT 2022
Engineered red blood cells carrying PCSK9 inhibitors persistently lower LDL and prevent obesity.
PloS one
Deshycka R,Sudaryo V,Huang NJ,Xie Y,Smeding LY,Choi MK,Ploegh HL,Lodish HF,Pishesha N
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Fri Dec 24 00:00:00 EST 2021
GRHL3 activates FSCN1 to relax cell-cell adhesions between migrating keratinocytes during wound reepithelialization.
JCI insight
Kashgari G,Venkatesh S,Refuerzo S,Pham B,Bayat A,Klein RH,Ramos R,Ta AP,Plikus MV,Wang PH,Andersen B
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Wed Sep 08 00:00:00 EDT 2021
The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.
eLife
Roy A,Tomaz da Silva M,Bhat R,Bohnert KR,Iwawaki T,Kumar A
12-5921-82 was used in Flow Cytometry to demonstrate that IRE1α (also known as ERN1) and its downstream target, XBP1, are activated in skeletal muscle of mice upon injury.
Tue Nov 23 00:00:00 EST 2021
SnRNA sequencing defines signaling by RBC-derived extracellular vesicles in the murine heart.
Life science alliance
Valkov N,Das A,Tucker NR,Li G,Salvador AM,Chaffin MD,Pereira De Oliveira Junior G,Kur I,Gokulnath P,Ziegler O,Yeri A,Lu S,Khamesra A,Xiao C,Rodosthenous R,Srinivasan S,Toxavidis V,Tigges J,Laurent LC,Momma S,Kitchen R,Ellinor P,Ghiran I,Das S
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Wed Dec 01 00:00:00 EST 2021
Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors.
Cell reports. Medicine
Kosti P,Opzoomer JW,Larios-Martinez KI,Henley-Smith R,Scudamore CL,Okesola M,Taher MYM,Davies DM,Muliaditan T,Larcombe-Young D,Woodman N,Gillett CE,Thavaraj S,Maher J,Arnold JN
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Tue Apr 20 00:00:00 EDT 2021
Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response.
Immunity
Glaros V,Rauschmeier R,Artemov AV,Reinhardt A,Ols S,Emmanouilidi A,Gustafsson C,You Y,Mirabello C,Björklund ÅK,Perez L,King NP,Månsson R,Angeletti D,Loré K,Adameyko I,Busslinger M,Kreslavsky T
12-5921-82 was used in Flow cytometry/Cell sorting to examine the early B cell response to T-dependent antigen in mice by single-cell RNA sequencing.
Tue Sep 14 00:00:00 EDT 2021
The AP-1 Transcription Factor Fosl-2 Regulates Autophagy in Cardiac Fibroblasts during Myocardial Fibrogenesis.
International journal of molecular sciences
Seidenberg J,Stellato M,Hukara A,Ludewig B,Klingel K,Distler O,Błyszczuk P,Kania G
12-5921-82 was used in Flow Cytometry to demonstrate that Fosl-2 regulates autophagocytosis and the TGF-β-Fosl-2-autophagy axis controls differentiation of cardiac fibroblasts.
Sat Feb 13 00:00:00 EST 2021
Sex Matters: Physiological Abundance of Immuno-Regulatory CD71+ Erythroid Cells Impair Immunity in Females.
Frontiers in immunology
Mashhouri S,Koleva P,Huynh M,Okoye I,Shahbaz S,Elahi S
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Mon Dec 20 00:00:00 EST 2021
Inhibition of TGFβ improves hematopoietic stem cell niche and ameliorates cancer-related anemia.
Stem cell research & therapy
Wang B,Wang Y,Chen H,Yao S,Lai X,Qiu Y,Cai J,Huang Y,Wei X,Guan Y,Wang T,Wang J,Xiang AP
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Mon Jan 18 00:00:00 EST 2021
Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas.
Science advances
Heino S,Fang S,Lähde M,Högström J,Nassiri S,Campbell A,Flanagan D,Raven A,Hodder M,Nasreddin N,Xue HH,Delorenzi M,Leedham S,Petrova TV,Sansom O,Alitalo K
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Fri Nov 19 00:00:00 EST 2021
Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease.
Nature communications
Garcia-Gomez A,Li T,de la Calle-Fabregat C,Rodríguez-Ubreva J,Ciudad L,Català-Moll F,Godoy-Tena G,Martín-Sánchez M,San-Segundo L,Muntión S,Morales X,Ortiz-de-Solórzano C,Oyarzabal J,San José-Enériz E,Esteller M,Agirre X,Prosper F,Garayoa M,Ballestar E
12-5921-82 was used in Flow Cytometry to study the efficacy of targeting methylation in myeloma bone disease.
Mon Jan 18 00:00:00 EST 2021
C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor.
Cancer cell
Di Genua C,Valletta S,Buono M,Stoilova B,Sweeney C,Rodriguez-Meira A,Grover A,Drissen R,Meng Y,Beveridge R,Aboukhalil Z,Karamitros D,Belderbos ME,Bystrykh L,Thongjuea S,Vyas P,Nerlov C
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Mon May 11 00:00:00 EDT 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression.
Developmental cell
Marsh T,Kenific CM,Suresh D,Gonzalez H,Shamir ER,Mei W,Tankka A,Leidal AM,Kalavacherla S,Woo K,Werb Z,Debnath J
12-5921 was used in Flow cytometry/Cell sorting to reveal that autophagy gene expression inversely correlates with pro-metastatic differentiation signatures and predicts overall and distant metastasis-free survival.
Mon Mar 09 00:00:00 EDT 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
Methylation of a CGATA element inhibits binding and regulation by GATA-1.
Nature communications
Yang L,Chen Z,Stout ES,Delerue F,Ittner LM,Wilkins MR,Quinlan KGR,Crossley M
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Fri May 22 00:00:00 EDT 2020
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation.
Nature communications
Kim JM,Yang YS,Park KH,Ge X,Xu R,Li N,Song M,Chun H,Bok S,Charles JF,Filhol-Cochet O,Boldyreff B,Dinter T,Yu PB,Kon N,Gu W,Takarada T,Greenblatt MB,Shim JH
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Fri May 08 00:00:00 EDT 2020
Meningeal lymphatics clear erythrocytes that arise from subarachnoid hemorrhage.
Nature communications
Chen J,Wang L,Xu H,Xing L,Zhuang Z,Zheng Y,Li X,Wang C,Chen S,Guo Z,Liang Q,Wang Y
12-5921 was used in Immunohistochemistry-immunofluorescence to demonstrate that the meningeal lymphatics drain extravasated erythrocytes from CSF into CLNs after SAH, while suggesting that modulating this draining may offer therapeutic approaches to alleviate SAH severity.
Mon Jun 22 00:00:00 EDT 2020
Splicing variation of BMP2K balances abundance of COPII assemblies and autophagic degradation in erythroid cells.
eLife
Cendrowski J,Kaczmarek M,Mazur M,Kuzmicz-Kowalska K,Jastrzebski K,Brewinska-Olchowik M,Kominek A,Piwocka K,Miaczynska M
12-5921-81 was used in Flow Cytometry to investigate the role of the longer(L) and shorter(S) splicing variant of bone morphogenetic protein 2-inducible kinase(BMP2K) in endocytosis and cell differentiation.
Fri Aug 14 00:00:00 EDT 2020
Loss of FGFR3 Delays Acute Myeloid Leukemogenesis by Programming Weakly Pathogenic CD117-Positive Leukemia Stem-Like Cells.
Frontiers in pharmacology
Guo C,Ran Q,Sun C,Zhou T,Yang X,Zhang J,Pang S,Xiao Y
12-5921-82 was used in Flow Cytometry to find that FGFR3 had a novel regulatory mechanism for the stemness of LSCs in AML, and provided a promising anti-leukemia approach by interrupting FGFR3.
Tue Feb 16 00:00:00 EST 2021
Polyisocyanide Hydrogels as a Tunable Platform for Mammary Gland Organoid Formation.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Tang C,Span PN,Rowan AE,Aalders TW,Schalken JA,Adema GJ,Kouwer PHJ,Zegers MMP,Ansems M
12-5921 was used in Flow cytometry/Cell sorting to present a well-defined, synthetic biomimetic matrix based on polyisocyanide (PIC) hydrogels that support efficient and reproducible formation of mammary gland organoids (MGOs) in vitro.
Tue Sep 01 00:00:00 EDT 2020
The Innate Immune Response to Infection Induces Erythropoietin-Dependent Replenishment of the Dendritic Cell Compartment.
Frontiers in immunology
Einwächter H,Heiseke A,Schlitzer A,Gasteiger G,Adler H,Voehringer D,Manz MG,Ruzsics Z,Dölken L,Koszinowski UH,Sparwasser T,Reindl W,Jordan S
12-5921-82 was used in Flow Cytometry to investigate the molecular and cellular mechanisms of inflammation-induced dendritic cell generation.
Mon Apr 19 00:00:00 EDT 2021
Id1 and Id3 Maintain Steady-State Hematopoiesis by Promoting Sinusoidal Endothelial Cell Survival and Regeneration.
Cell reports
Gadomski S,Singh SK,Singh S,Sarkar T,Klarmann KD,Berenschot M,Seaman S,Jakubison B,Gudmundsson KO,Lockett S,Keller JR
12-5921 was used in Flow cytometry/Cell sorting to investigate the effects of loss of ld genes on adult endothelial cell.
Tue Apr 28 00:00:00 EDT 2020
Single cell transcriptome dynamics from pluripotency to FLK1+ mesoderm.
Development (Cambridge, England)
Zhao H,Choi K
12-5921 was used in Flow cytometry/Cell sorting to study the continuous developmental process leading to hemangiogenesis by performing single cell RNA sequencing of in vitro-differentiated mouse embryonic stem cells.
Thu Dec 05 00:00:00 EST 2019
Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice.
PLoS genetics
Madaro L,Torcinaro A,De Bardi M,Contino FF,Pelizzola M,Diaferia GR,Imeneo G,Bouchè M,Puri PL,De Santa F
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion.
Immunity
Xia P,Wang S,Ye B,Du Y,Li C,Xiong Z,Qu Y,Fan Z
12-5921 was used in Flow cytometry/Cell sorting to study circular RNA-mediated maintenance of hematopoeitic stem cell homeostasis.
Tue Apr 17 00:00:00 EDT 2018
Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation.
The Journal of experimental medicine
Nagase R,Inoue D,Pastore A,Fujino T,Hou HA,Yamasaki N,Goyama S,Saika M,Kanai A,Sera Y,Horikawa S,Ota Y,Asada S,Hayashi Y,Kawabata KC,Takeda R,Tien HF,Honda H,Abdel-Wahab O,Kitamura T
12-5921 was used in Flow cytometry/Cell sorting to study the effects of physiological expression of a C-terminal truncated AsXenopus laevis1 mutant in vivo.
Mon Jun 04 00:00:00 EDT 2018
MyD88 is required for satellite cell-mediated myofiber regeneration in dystrophin-deficient mdx mice.
Human molecular genetics
Gallot YS,Straughn AR,Bohnert KR,Xiong G,Hindi SM,Kumar A
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2018
Clonal expansion and myeloid leukemia progression modeled by multiplex gene editing of murine hematopoietic progenitor cells.
Experimental hematology
Shi X,Kitano A,Jiang Y,Luu V,Hoegenauer KA,Nakada D
12-5921 was used in Flow cytometry/Cell sorting to establish that the CRISPR/Cas9-mediated multiplex mutagenesis can be used to engineer a variety of murine models of hematological malignancies with complex genetic architectures seen in human disease.
Wed Aug 01 00:00:00 EDT 2018
Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.
Nature communications
Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Fri Jun 22 00:00:00 EDT 2018
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Tue Dec 11 00:00:00 EST 2018
Global loss of leucine carboxyl methyltransferase-1 causes severe defects in fetal liver hematopoiesis.
The Journal of biological chemistry
Lee JA,Wang Z,Sambo D,Bunting KD,Pallas DC
12-5921 was used in Flow cytometry/Cell sorting to reveal a novel role for LCMT-1 as a key player in fetal liver hematopoiesis.
Fri Jun 22 00:00:00 EDT 2018
Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling.
Cell
Ho CCM,Chhabra A,Starkl P,Schnorr PJ,Wilmes S,Moraga I,Kwon HS,Gaudenzio N,Sibilano R,Wehrman TS,Gakovic M,Sockolosky JT,Tiffany MR,Ring AM,Piehler J,Weissman IL,Galli SJ,Shizuru JA,Garcia KC
12-5921 was used in Flow cytometry/Cell sorting to develop a mechanism-based stem cell factor partial agonist that impairs c-Kit dimerisation, truncating downstream signalling amplitude.
Thu Mar 09 00:00:00 EST 2017
Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production.
Immunity
Dalmas E,Lehmann FM,Dror E,Wueest S,Thienel C,Borsigova M,Stawiski M,Traunecker E,Lucchini FC,Dapito DH,Kallert SM,Guigas B,Pattou F,Kerr-Conte J,Maechler P,Girard JP,Konrad D,Wolfrum C,Böni-Schnetzler M,Finke D,Donath MY
12-5921 was used in Flow cytometry/Cell sorting to provide evidence that an immunometabolic crosstalk between islet-derived IL-33, ILC2s, and myeloid cells fosters insulin secretion.
Tue Nov 21 00:00:00 EST 2017
Increased Vascular Permeability in the Bone Marrow Microenvironment Contributes to Disease Progression and Drug Response in Acute Myeloid Leukemia.
Cancer cell
Passaro D,Di Tullio A,Abarrategi A,Rouault-Pierre K,Foster K,Ariza-McNaughton L,Montaner B,Chakravarty P,Bhaw L,Diana G,Lassailly F,Gribben J,Bonnet D
12-5921-82 was used in Flow Cytometry to find several abnormalities in the vascular architecture and function in patient-derived xenografts (PDX), such as vascular leakiness and increased hypoxia.
Mon Sep 11 00:00:00 EDT 2017
Differential cytokine contributions of perivascular haematopoietic stem cell niches.
Nature cell biology
Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis.
The Journal of clinical investigation
Géraud C,Koch PS,Zierow J,Klapproth K,Busch K,Olsavszky V,Leibing T,Demory A,Ulbrich F,Diett M,Singh S,Sticht C,Breitkopf-Heinlein K,Richter K,Karppinen SM,Pihlajaniemi T,Arnold B,Rodewald HR,Augustin HG,Schledzewski K,Goerdt S
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Single cell transcriptomics reveals unanticipated features of early hematopoietic precursors.
Nucleic acids research
Yang J,Tanaka Y,Seay M,Li Z,Jin J,Garmire LX,Zhu X,Taylor A,Li W,Euskirchen G,Halene S,Kluger Y,Snyder MP,Park IH,Pan X,Weissman SM
12-5921 was used in Flow cytometry/Cell sorting to study the effects of cell cycle progression on the expression of lineage specific genes in precursor cells.
Fri Feb 17 00:00:00 EST 2017
Bim suppresses the development of SLE by limiting myeloid inflammatory responses.
The Journal of experimental medicine
Tsai F,Homan PJ,Agrawal H,Misharin AV,Abdala-Valencia H,Haines GK,Dominguez S,Bloomfield CL,Saber R,Chang A,Mohan C,Hutcheson J,Davidson A,Budinger GRS,Bouillet P,Dorfleutner A,Stehlik C,Winter DR,Cuda CM,Perlman H
12-5921 was used in Neutralization to suggest that the Bim may be a novel therapeutic target in the treatment of SLE.
Mon Dec 04 00:00:00 EST 2017
GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia.
Developmental cell
Hewitt KJ,Katsumura KR,Matson DR,Devadas P,Tanimura N,Hebert AS,Coon JJ,Kim JS,Dewey CN,Keles S,Hao S,Paulson RF,Bresnick EH
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Mon Aug 07 00:00:00 EDT 2017
Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease.
Proceedings of the National Academy of Sciences of the United States of America
Pishesha N,Bilate AM,Wibowo MC,Huang NJ,Li Z,Deshycka R,Bousbaine D,Li H,Patterson HC,Dougan SK,Maruyama T,Lodish HF,Ploegh HL
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Tue Mar 21 00:00:00 EDT 2017
Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity.
Breast cancer research : BCR
Chamberlin T,D'Amato JV,Arendt LM
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Wed Nov 29 00:00:00 EST 2017
Human umbilical cord blood-borne fibroblasts contain marrow niche precursors that form a bone/marrow organoid in vivo.
Development (Cambridge, England)
Pievani A,Sacchetti B,Corsi A,Rambaldi B,Donsante S,Scagliotti V,Vergani P,Remoli C,Biondi A,Robey PG,Riminucci M,Serafini M
12-5921 was used in Flow cytometry/Cell sorting to show that human umbilical cord blood-borne fibroblasts are able to recapitulate the conditions by which the bone marrow microenvironment is formed and establish complete hematopoietic stem cell niches.
Wed Mar 15 00:00:00 EDT 2017
The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration.
eLife
Xiong G,Hindi SM,Mann AK,Gallot YS,Bohnert KR,Cavener DR,Whittemore SR,Kumar A
12592182 was used in flow cytometry to examine the impact of the unfolded protein response in satellite cell homeostasis during regenerative myogenesis
Thu Mar 23 00:00:00 EDT 2017
Prolonged activation of IL-5-producing ILC2 causes pulmonary arterial hypertrophy.
JCI insight
Ikutani M,Tsuneyama K,Kawaguchi M,Fukuoka J,Kudo F,Nakae S,Arita M,Nagai Y,Takaki S,Takatsu K
12-5921 was used in Flow cytometry/Cell sorting to demonstrate a previously unrecognized mechanism in the development of pulmonary arterial hypertrophy and the causative roles of ILC2 in the process.
Thu Apr 06 00:00:00 EDT 2017
The mouse Char10 locus regulates severity of pyruvate kinase deficiency and susceptibility to malaria.
PloS one
Laroque A,Min-Oo G,Tam M,Ponka P,Stevenson MM,Gros P
12-5921 was used in Flow cytometry/Cell sorting to study the mechanistic basis of the Char10 effect.
Tue Sep 12 00:00:00 EDT 2017
Age-dependent modulation of vascular niches for haematopoietic stem cells.
Nature
Kusumbe AP,Ramasamy SK,Itkin T,Mäe MA,Langen UH,Betsholtz C,Lapidot T,Adams RH
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Thu Apr 21 00:00:00 EDT 2016
Pyk2 is essential for astrocytes mobility following brain lesion.
Glia
Giralt A,Coura R,Girault JA
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2016
A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.
Nature communications
Jeric I,Maurer G,Cavallo AL,Raguz J,Desideri E,Tarkowski B,Parrini M,Fischer I,Zatloukal K,Baccarini M
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Wed Dec 21 00:00:00 EST 2016
MHC-compatible bone marrow stromal/stem cells trigger fibrosis by activating host T cells in a scleroderma mouse model.
eLife
Ogawa Y,Morikawa S,Okano H,Mabuchi Y,Suzuki S,Yaguchi T,Sato Y,Mukai S,Yaguchi S,Inaba T,Okamoto S,Kawakami Y,Tsubota K,Matsuzaki Y,Shimmura S
12-5921 was used in Flow cytometry/Cell sorting to investigate the fibrosis in a scleroderma mouse model which is triggered by antigen mismatched bone marrow stromal/stem cells.
Tue Jan 26 00:00:00 EST 2016
Clec11a/osteolectin is an osteogenic growth factor that promotes the maintenance of the adult skeleton.
eLife
Yue R,Shen B,Morrison SJ
12-5921 was used in Flow cytometry/Cell sorting to study how Clec11a/Osteolectin maintains the adult skeleton by promoting the differentiation of mesenchymal progenitors into mature osteoblasts.
Tue Dec 13 00:00:00 EST 2016
Hypoxia sensing through β-adrenergic receptors.
JCI insight
Cheong HI,Asosingh K,Stephens OR,Queisser KA,Xu W,Willard B,Hu B,Dermawan JKT,Stark GR,Naga Prasad SV,Erzurum SC
12-5921 was used in Flow cytometry/Cell sorting to study the underlying mechanisms by which cells sense hypoxia.
Thu Dec 22 00:00:00 EST 2016
PPAR-α and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal.
Nature
Lee HY,Gao X,Barrasa MI,Li H,Elmes RR,Peters LL,Lodish HF
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Thu Jun 25 00:00:00 EDT 2015
CD93 Marks a Non-Quiescent Human Leukemia Stem Cell Population and Is Required for Development of MLL-Rearranged Acute Myeloid Leukemia.
Cell stem cell
Iwasaki M,Liedtke M,Gentles AJ,Cleary ML
12-5921 was used in Flow cytometry/Cell sorting to study how CD93 expression may indicate leukaemia initiating stem cells that have a MLL gene rearrangement.
Thu Oct 01 00:00:00 EDT 2015
Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells.
The Journal of clinical investigation
Hadland BK,Varnum-Finney B,Poulos MG,Moon RT,Butler JM,Rafii S,Bernstein ID
12-5921 was used in Flow cytometry/Cell sorting to investigate the critical niche components and resident signals required for hematopoietic stem cell induction and self-renewal ex vivo.
Fri May 01 00:00:00 EDT 2015
Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors.
The Journal of clinical investigation
Henry CJ,Casás-Selves M,Kim J,Zaberezhnyy V,Aghili L,Daniel AE,Jimenez L,Azam T,McNamee EN,Clambey ET,Klawitter J,Serkova NJ,Tan AC,Dinarello CA,DeGregori J
12-5921 was used in Flow cytometry/Cell sorting to conclude that chronic inflammatory microenvironments in old age lead to reductions in the fitness of B cell progenitor populations.
Tue Dec 01 00:00:00 EST 2015
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Genome-wide association study follow-up identifies cyclin A2 as a regulator of the transition through cytokinesis during terminal erythropoiesis.
American journal of hematology
Ludwig LS,Cho H,Wakabayashi A,Eng JC,Ulirsch JC,Fleming MD,Lodish HF,Sankaran VG
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2015
Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis.
Cell death and differentiation
Cho J,Seo J,Lim CH,Yang L,Shiratsuchi T,Lee MH,Chowdhury RR,Kasahara H,Kim JS,Oh SP,Lee YJ,Terada N
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Pretreatment of Mesenchymal Stem Cells Manipulates Their Vasculoprotective Potential While Not Altering Their Homing Within the Injured Gut.
Stem cells (Dayton, Ohio)
Kavanagh DP,Suresh S,Newsome PN,Frampton J,Kalia N
12-5921 was used in Flow cytometry/Cell sorting to demonstrate that MSCs can limit leukocyte recruitment and improve tissue perfusion following intestinal ischemia-reperfusion injury.
Tue Sep 01 00:00:00 EDT 2015
Does FACS perturb gene expression?
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Richardson GM,Lannigan J,Macara IG
12-5921 was used in Flow cytometry/Cell sorting to examine the effects of fluorescence activated cell sorting separation on short-term transcriptional profiles.
Sun Feb 01 00:00:00 EST 2015
Non-invasive imaging and cellular tracking of pulmonary emboli by near-infrared fluorescence and positron-emission tomography.
Nature communications
Page MJ,Lourenço AL,David T,LeBeau AM,Cattaruzza F,Castro HC,VanBrocklin HF,Coughlin SR,Craik CS
12-5921 was used in Immunohistochemistry-immunofluorescence to demonstrate non-invasive detection of thrombin generation in a murine model of pulmonary embolism using protease-activated peptide probes in microscopic clots within the lungs.
Thu Oct 01 00:00:00 EDT 2015
Overexpressing sonic hedgehog peptide restores periosteal bone formation in a murine bone allograft transplantation model.
Molecular therapy : the journal of the American Society of Gene Therapy
Huang C,Tang M,Yehling E,Zhang X
12-5921 was used in Flow cytometry/Cell sorting to show that overexpression of ShhN in mesenchymal progenitors improves bone defect reconstruction.
Sat Feb 01 00:00:00 EST 2014
CD41 is a reliable identification and activation marker for murine basophils in the steady state and during helminth and malarial infections.
European journal of immunology
Bakocevic N,Claser C,Yoshikawa S,Jones LA,Chew S,Goh CC,Malleret B,Larbi A,Ginhoux F,de Lafaille MC,Karasuyama H,Renia L,Ng LG
12-5921 was used in Flow cytometry/Cell sorting to study the CD41 expression within basophils from the blood during both steady state and malarial inections within mice.
Sun Jun 01 00:00:00 EDT 2014
Inactivation of Rb and E2f8 synergizes to trigger stressed DNA replication during erythroid terminal differentiation.
Molecular and cellular biology
Ghazaryan S,Sy C,Hu T,An X,Mohandas N,Fu H,Aladjem MI,Chang VT,Opavsky R,Wu L
12-5921 was used in Flow cytometry/Cell sorting to show that during erythroid terminal differentiation, Rb promotes DNA replication and cell cycle progression.
Fri Aug 01 00:00:00 EDT 2014
Oncostatin M maintains the hematopoietic microenvironment in the bone marrow by modulating adipogenesis and osteogenesis.
PloS one
Sato F,Miyaoka Y,Miyajima A,Tanaka M
12-5921 was used in Flow cytometry/Cell sorting to investigate the mechanisms underlying mesenchymal stromal cell differentiation, showing that oncostatin M maintains the hematopoietic microenvironment in the bone marrow.
Wed May 04 00:00:00 EDT 2016
Oncostatin M maintains the hematopoietic microenvironment in the bone marrow by modulating adipogenesis and osteogenesis.
PloS one
Sato F,Miyaoka Y,Miyajima A,Tanaka M
12-5921 was used in Flow cytometry/Cell sorting to investigate the mechanisms underlying mesenchymal stromal cell differentiation, showing that oncostatin M maintains the hematopoietic microenvironment in the bone marrow.
Wed May 04 00:00:00 EDT 2016
Enteroendocrine cells are specifically marked by cell surface expression of claudin-4 in mouse small intestine.
PloS one
Nagatake T,Fujita H,Minato N,Hamazaki Y
12-5921 was used in Flow cytometry/Cell sorting to demonstrate that enteroendocrine cells selectively express a tight junction membrane protein, claudin-4.
Thu Feb 12 00:00:00 EST 2015
A comprehensive analysis of GATA-1-regulated miRNAs reveals miR-23a to be a positive modulator of erythropoiesis.
Nucleic acids research
Zhu Y,Wang D,Wang F,Li T,Dong L,Liu H,Ma Y,Jiang F,Yin H,Yan W,Luo M,Tang Z,Zhang G,Wang Q,Zhang J,Zhou J,Yu J
12-5921 was used in Flow cytometry/Cell sorting to identify a key GATA-1-miRNA axis in erythroid differentiation.
Mon Apr 01 00:00:00 EDT 2013
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.
Development (Cambridge, England)
Liu B,Liu YF,Du YR,Mardaryev AN,Yang W,Chen H,Xu ZM,Xu CQ,Zhang XR,Botchkarev VA,Zhang Y,Xu GL
12-5921 was used in Flow cytometry/Cell sorting to demonstrate an essential and non-redundant role for Cbx4 in thymic organogenesis.
Fri Feb 01 00:00:00 EST 2013
IL-33 signaling regulates innate and adaptive immunity to Cryptococcus neoformans.
Journal of immunology (Baltimore, Md. : 1950)
Flaczyk A,Duerr CU,Shourian M,Lafferty EI,Fritz JH,Qureshi ST
12-5921 was used in Flow cytometry/Cell sorting to study how allergic patterns of lung inflammation are mediated as a host response to Cryptococcus neoformans infection.
Sun Sep 01 00:00:00 EDT 2013
Disruption of the Hbs1l-Myb locus causes hereditary persistence of fetal hemoglobin in a mouse model.
Molecular and cellular biology
Suzuki M,Yamazaki H,Mukai HY,Motohashi H,Shi L,Tanabe O,Engel JD,Yamamoto M
12-5921 was used in Flow cytometry/Cell sorting to report a new mouse model of hereditary persistence of fetal hemoglobin in which the Hbs1l-Myb locus is disrupted.
Mon Apr 01 00:00:00 EDT 2013
CD8(+) T cell activation by murine erythroblasts infected with malaria parasites.
Scientific reports
Imai T,Ishida H,Suzue K,Hirai M,Taniguchi T,Okada H,Suzuki T,Shimokawa C,Hisaeda H
12-5921 was used in Flow cytometry/Cell sorting to examine the parasitism of erythroblasts by P. falciparum and P. vivax and the immune response towards them.
Mon Sep 16 00:00:00 EDT 2013
Concomitant inactivation of Rb and E2f8 in hematopoietic stem cells synergizes to induce severe anemia.
Blood
Hu T,Ghazaryan S,Sy C,Wiedmeyer C,Chang V,Wu L
Published figure using TER-119 monoclonal antibody (Product # 12-5921-82) in Flow Cytometry
Thu May 10 00:00:00 EDT 2012
NF-Y is necessary for hematopoietic stem cell proliferation and survival.
Blood
Bungartz G,Land H,Scadden DT,Emerson SG
12-5921 was used in Flow cytometry/Cell sorting to show that the trimeric transcription factor NF-Y is critical for the survival of cycling, but not quiescent hematopoietic stem cells.
Thu Feb 09 00:00:00 EST 2012
IKKα-mediated signaling circuitry regulates early B lymphopoiesis during hematopoiesis.
Blood
Balkhi MY,Willette-Brown J,Zhu F,Chen Z,Liu S,Guttridge DC,Karin M,Hu Y
12-5921-82 was used in Flow Cytometry to demonstrate that IKKα regulates B-lineage commitment via combined canonical and noncanonical NF-κB transcriptional activities to target Pax5 expression during hematopoiesis.
Thu Jun 07 00:00:00 EDT 2012
Thymus-autonomous T cell development in the absence of progenitor import.
The Journal of experimental medicine
Martins VC,Ruggiero E,Schlenner SM,Madan V,Schmidt M,Fink PJ,von Kalle C,Rodewald HR
12-5921 was used in Flow cytometry/Cell sorting to characterise the previously unrecognised capacity of the thymus to sustain T cell development during bone marrow progenitor deprivation.
Mon Jul 30 00:00:00 EDT 2012
Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice.
The Journal of experimental medicine
Christopher MJ,Rao M,Liu F,Woloszynek JR,Link DC
12-5921 was used in Flow cytometry/Cell sorting to suggest a model in which G-CSFR signals in bone marrow monocytic cells inhibit the production of trophic factors required for osteoblast lineage cell maintenance.
Mon Feb 14 00:00:00 EST 2011
Role of phosphatidylinositol 3-kinase in friend spleen focus-forming virus-induced erythroid disease.
Journal of virology
Umehara D,Watanabe S,Ochi H,Anai Y,Ahmed N,Kannagi M,Hanson C,Ruscetti S,Nishigaki K
12-5921 was used in Flow cytometry/Cell sorting to indicate that p85alpha may regulate short form-Stk-dependent erythroid proliferation induced by Friend spleen focus-forming virus and stress-induced erythroid hyperplasia.
Sun Aug 01 00:00:00 EDT 2010
Pregnancy alters the proliferation and apoptosis of mouse splenic erythroid lineage cells and leukocytes.
Biology of reproduction
Norton MT,Fortner KA,Bizargity P,Bonney EA
12-5921 was used in Flow cytometry/Cell sorting to show that erythroid-lineage TER-119(+) cells expanded significantly in midgestation because of enhanced proliferation and diminished apoptosis.
Tue Sep 01 00:00:00 EDT 2009
Proper levels of c-Myb are discretely defined at distinct steps of hematopoietic cell development.
Blood
Sakamoto H,Dai G,Tsujino K,Hashimoto K,Huang X,Fujimoto T,Mucenski M,Frampton J,Ogawa M
12-5921 was used in Flow cytometry/Cell sorting to investigate the functional role of c-Myb in hematopoietic cell development from endothelial cells, showing that proper levels of c-Myb are discretely defined at distinct steps of development.
Tue Aug 01 00:00:00 EDT 2006
Beta-catenin is dispensable for hematopoiesis and lymphopoiesis.
The Journal of experimental medicine
Cobas M,Wilson A,Ernst B,Mancini SJ,MacDonald HR,Kemler R,Radtke F
12-5921 was used in Flow cytometry/Cell sorting to investigate an essential role for beta-catenin during hematopoiesis and lymphopoiesis.
Mon Jan 19 00:00:00 EST 2004
