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Vaccine Research and Development
Tools to Improve Health Outcomes
Reliable solutions for all stages of vaccine development
We offer innovative solutions across the vaccine research and development workflow that help you ensure the efficacy, quality, and safety of the therapies you develop. From the identification, synthesis, and optimization of targets to vaccine production, delivery, and testing, Thermo Fisher Scientific provides expertise and an unparalleled array of reliable and scalable tools, services, and support to help you accelerate your productivity and innovation. We invite you to partner with us to reach your vaccine development goals.
View our comprehensive list of products, services, and technologies to support you at every step of vaccine development:
Target discovery
Characterizing the pathogen, understanding the host response, and studying host–pathogen interactions is critical for understanding emerging disease threats and identifying variation among pathogen strains.
Featured products
KingFisher purification systems
Save valuable time with benchtop automation in extraction and purification of DNA, RNA, protein, and cells
Collibri NGS library preparation kits for Illumina systems
Generate NGS libraries quickly with less bias and match the speed and capacity of llumina instruments
Biological safety cabinets
Maximize sample protection and user safety, with containment, comfort and convenience, all day, every day.
ProcartaPlex Immunoassays
Multiplex protein quantitation using the Luminex instrument platform, covering >300 cytokines, chemokines, growth factors, and other protein targets.
Viral or bacterial DNA/RNA isolation
Purify high-quality nucleic acid from a range of sample types both manually and with automated systems, using magnetic bead–based technology.
Viral or bacterial DNA/RNA isolation with vacuum concentration
Achieve efficient concentration and preservation of heat-sensitive biological samples through solvent removal
Sequencing solutions
Wide range of sequencing solutions from gold-standard Sanger sequencing technology, to flexible and scalable next-generation sequencing (NGS) products.
NGS library preparation kits for Illumina platforms
Enhance next-generation sequencing (NGS)-based viral surveillance with higher quality sequences and rapid protocols.
Pathogen protein analysis
Observe biological structures in their near-native states with cryo electron microscopy techniques for structural characterization of pathogens.
Viral proteomics & metabolomics by mass spectrometry
Mass spectrometry (MS) techniques such as proteomics, glycomics and metabolomics help advance the understanding of pathogens.
Pathogen protein expression
High-yield expression systems for expressing recombinant pathogen proteins with more native folding and post-translational modifications
Virus neutralization
High-throughput automated imaging of cell-based virus neutralization assays
Receptors and other entry factors
Gene expression assays for viral targets including a variety of host entry factor targets.
Tracking internalization
An extensive portfolio of cell imaging products and technologies to help researchers track the internalization of viral particles.
High-content screening analysis
Exceptional resolution with subcellular, automated detection and phenotyping with intact, fixed, or live cells.
Gene expression analysis by qPCR
Predesigned qPCR Gene Expression Assays to quantitate expression levels of immunology transcripts involved in the host response to viral infection
NGS
Rapid, multi-dimensional genetic analysis at scale to quickly sequence DNA and RNA to understand the genetics behind viral response
Mass spectrometry
System wide quantitative proteomics with highly sensitive and accurate mass spectrometry. Study thousands of proteins in a single experiment
Immune response analysis by flow cytometry
Flow cytometry instruments, assays, reagents, and antibodies to simultaneously analyze multiple proteins, gene expression, and cell functions
Immunoassays
Matched antibody pairs, uncoated/coated-plate ELISA kits, and multiplexing assays for the Luminex platform. Validated for reliability and specificity
Automated reagent dispensing
Increase throughput, reproducibility, and speed through automated reagent dispensing
Candidate vaccine synthesis & functional analysis
Select a suitable antigen and develop a vaccine that will provide lasting immunity by stimulating a memory T-cell response and driving memory B cell formation.
Quick links: Candidate vaccine synthesis | Functional analysis | Commercialization solutions | Resources
Featured products
GeneArt Gene Synthesis and Protein Services
Reliable and cost-effective method for obtaining customized DNA constructs with 100% sequence accuracy
CellInsight CX7 LZR Pro HCS Platform
A fast, laser-based, automated cellular imaging and analysis platform for quantitative microscopy and phenotypic screening.
Invitrogen EVOS M7000 Imaging System
High-performance, fully automated, inverted, multi-channel fluorescence and transmitted light imaging system
Attenuated vaccine
Serum-free media without compromising growth or titer. A broad selection of animal origin-free formulations that support major vaccine cell lines
Protein subunit vaccine
Superior recombinant protein expression technology systems for consistency, high yields, and rapid protein production.
mRNA vaccine
Breadth and depth of technologies and resources to support production. Scalable systems for mRNA synthesis, purification, formulation and delivery.
Nucleic acid vaccine
A range of phosphoramidites and solid supports for oligonucleotide synthesis from early research to preclinical candidates.
Cell function assays
Cell-based assays and reagents for key cellular processes, including apoptosis, cell proliferation, cell cycle and viability
Biodistribution assays
A range of products for imaging biological processes in live animals to understand cellular activity, effects of drugs, and disease progression
Cell model creation
Closely mimic the in vivo state and generate more physiologically relevant data physiologically relevant data with complete cell culture systems for drug discovery
Immune response analysis by flow cytometry
Simultaneously analyze multiple proteins, gene expression, and cell functions such as oxidation, viability, cell cycle, apoptosis, and proliferation.
Immunoassays
Antibody-based, target-specific protein quantitation reagents, kits, and panels for analysis of intracellular and cell-surface targets
High-content screening
Platforms and software for cutting-edge images and high content imaging data in no time. Exceptional resolution with subcellular, automated detection
Mass spectrometry
Modern, quantitative mass spectrometry analyses to detect and quantify thousands of proteins in a single experiment across multiple conditions
CO2 incubators
Achieve your goals faster, more reliably, and with less effort, in contamination control and uniform growth conditions
Production process development
Solutions for producing vaccine and analytics for next stages.
Featured products
Media manufacturing services
We are committed to meeting your toughest challenges with high-performing Gibco products and services customized to your research and production needs.
Single-use bioprocessing
Our proven, scalable technologies include bioprocessing equipment and automation, and flexible and rigid containment
cGMP custom manufacturing
Take advantage of our fully validated cGMP media manufacturing services when you are ready for full-scale production.
TSX Series ultra-low freezers
Designed with features that support sustainability objectives without compromising performance.
Scale-up vaccine production technologies
Trusted solutions for rapid vaccine design, development, testing and production; improve quality and operational productivity and reduce costs
mRNA vaccine production
Breadth and depth of technologies and resources to support production; scalable systems for mRNA synthesis, purification, formulation and delivery
mRNA vaccine purification
Tailor-made affinity resin for efficient purification of mRNA constructs; scalable and suitable for commercial manufacturing
Bioprocessing centrifugation
Support your applications, from R&D to large-scale production with bioprocessing centrifuges to help maximize capacity, run-to-run reproducibility, and cGMP traceability
Residual host-cell DNA quantitation
Complete solution for extraction and quantitation of host-cell DNA from biopharmaceutical purification sample matrices
Residual plasmid quantitation
Accurate, rapid, and reproducible quantitation of residual plasmid DNA with resDNASEQ Quantitative Plasmid DNA Kit
Adventitious virus testing
Get accurate, rapid results from a system that is part of a total workflow solution and reduce your testing challenges in a GMP environment
AccuSEQ RT-PCR Software
Real-time PCR software that is part of a complete, validated solution for biopharmaceutical contaminant and impurity testing. Designed to help customers meet local regulatory requirements like 21 CFR Part 11 compliance.
Mycoplasma detection testing
Help ensure early detection of mycoplasma contamination and same day actionable results, with a sensitive real-time PCR based mycoplasma detection assay
Microbial identification
Rapid, accurate identification of thousands of bacterial and fungal species typically in under 5 hours
Purity test with SEC-HPLC
Separate biological molecules and polymers according to size using either SDS-PAGE / SEC-HPLC / capillary electrophoresis (reduced & nonreduced)
Sample preparation
A universal, magnetic bead-based sample preparation technology for efficient sample clean up for reproducible contaminant and impurity testing
Stability testing environmental chambers
Achieve testing consistency and regulatory compliance with temperature uniformity and stability
Target discovery
Characterizing the pathogen, understanding the host response, and studying host–pathogen interactions is critical for understanding emerging disease threats and identifying variation among pathogen strains.
Featured products
KingFisher purification systems
Save valuable time with benchtop automation in extraction and purification of DNA, RNA, protein, and cells
Collibri NGS library preparation kits for Illumina systems
Generate NGS libraries quickly with less bias and match the speed and capacity of llumina instruments
Biological safety cabinets
Maximize sample protection and user safety, with containment, comfort and convenience, all day, every day.
ProcartaPlex Immunoassays
Multiplex protein quantitation using the Luminex instrument platform, covering >300 cytokines, chemokines, growth factors, and other protein targets.
Viral or bacterial DNA/RNA isolation
Purify high-quality nucleic acid from a range of sample types both manually and with automated systems, using magnetic bead–based technology.
Viral or bacterial DNA/RNA isolation with vacuum concentration
Achieve efficient concentration and preservation of heat-sensitive biological samples through solvent removal
Sequencing solutions
Wide range of sequencing solutions from gold-standard Sanger sequencing technology, to flexible and scalable next-generation sequencing (NGS) products.
NGS library preparation kits for Illumina platforms
Enhance next-generation sequencing (NGS)-based viral surveillance with higher quality sequences and rapid protocols.
Pathogen protein analysis
Observe biological structures in their near-native states with cryo electron microscopy techniques for structural characterization of pathogens.
Viral proteomics & metabolomics by mass spectrometry
Mass spectrometry (MS) techniques such as proteomics, glycomics and metabolomics help advance the understanding of pathogens.
Pathogen protein expression
High-yield expression systems for expressing recombinant pathogen proteins with more native folding and post-translational modifications
Virus neutralization
High-throughput automated imaging of cell-based virus neutralization assays
Receptors and other entry factors
Gene expression assays for viral targets including a variety of host entry factor targets.
Tracking internalization
An extensive portfolio of cell imaging products and technologies to help researchers track the internalization of viral particles.
High-content screening analysis
Exceptional resolution with subcellular, automated detection and phenotyping with intact, fixed, or live cells.
Gene expression analysis by qPCR
Predesigned qPCR Gene Expression Assays to quantitate expression levels of immunology transcripts involved in the host response to viral infection
NGS
Rapid, multi-dimensional genetic analysis at scale to quickly sequence DNA and RNA to understand the genetics behind viral response
Mass spectrometry
System wide quantitative proteomics with highly sensitive and accurate mass spectrometry. Study thousands of proteins in a single experiment
Immune response analysis by flow cytometry
Flow cytometry instruments, assays, reagents, and antibodies to simultaneously analyze multiple proteins, gene expression, and cell functions
Immunoassays
Matched antibody pairs, uncoated/coated-plate ELISA kits, and multiplexing assays for the Luminex platform. Validated for reliability and specificity
Automated reagent dispensing
Increase throughput, reproducibility, and speed through automated reagent dispensing
Candidate vaccine synthesis & functional analysis
Select a suitable antigen and develop a vaccine that will provide lasting immunity by stimulating a memory T-cell response and driving memory B cell formation.
Quick links: Candidate vaccine synthesis | Functional analysis | Commercialization solutions | Resources
Featured products
GeneArt Gene Synthesis and Protein Services
Reliable and cost-effective method for obtaining customized DNA constructs with 100% sequence accuracy
CellInsight CX7 LZR Pro HCS Platform
A fast, laser-based, automated cellular imaging and analysis platform for quantitative microscopy and phenotypic screening.
Invitrogen EVOS M7000 Imaging System
High-performance, fully automated, inverted, multi-channel fluorescence and transmitted light imaging system
Attenuated vaccine
Serum-free media without compromising growth or titer. A broad selection of animal origin-free formulations that support major vaccine cell lines
Protein subunit vaccine
Superior recombinant protein expression technology systems for consistency, high yields, and rapid protein production.
mRNA vaccine
Breadth and depth of technologies and resources to support production. Scalable systems for mRNA synthesis, purification, formulation and delivery.
Nucleic acid vaccine
A range of phosphoramidites and solid supports for oligonucleotide synthesis from early research to preclinical candidates.
Cell function assays
Cell-based assays and reagents for key cellular processes, including apoptosis, cell proliferation, cell cycle and viability
Biodistribution assays
A range of products for imaging biological processes in live animals to understand cellular activity, effects of drugs, and disease progression
Cell model creation
Closely mimic the in vivo state and generate more physiologically relevant data physiologically relevant data with complete cell culture systems for drug discovery
Immune response analysis by flow cytometry
Simultaneously analyze multiple proteins, gene expression, and cell functions such as oxidation, viability, cell cycle, apoptosis, and proliferation.
Immunoassays
Antibody-based, target-specific protein quantitation reagents, kits, and panels for analysis of intracellular and cell-surface targets
High-content screening
Platforms and software for cutting-edge images and high content imaging data in no time. Exceptional resolution with subcellular, automated detection
Mass spectrometry
Modern, quantitative mass spectrometry analyses to detect and quantify thousands of proteins in a single experiment across multiple conditions
CO2 incubators
Achieve your goals faster, more reliably, and with less effort, in contamination control and uniform growth conditions
Production process development
Solutions for producing vaccine and analytics for next stages.
Featured products
Media manufacturing services
We are committed to meeting your toughest challenges with high-performing Gibco products and services customized to your research and production needs.
Single-use bioprocessing
Our proven, scalable technologies include bioprocessing equipment and automation, and flexible and rigid containment
cGMP custom manufacturing
Take advantage of our fully validated cGMP media manufacturing services when you are ready for full-scale production.
TSX Series ultra-low freezers
Designed with features that support sustainability objectives without compromising performance.
Scale-up vaccine production technologies
Trusted solutions for rapid vaccine design, development, testing and production; improve quality and operational productivity and reduce costs
mRNA vaccine production
Breadth and depth of technologies and resources to support production; scalable systems for mRNA synthesis, purification, formulation and delivery
mRNA vaccine purification
Tailor-made affinity resin for efficient purification of mRNA constructs; scalable and suitable for commercial manufacturing
Bioprocessing centrifugation
Support your applications, from R&D to large-scale production with bioprocessing centrifuges to help maximize capacity, run-to-run reproducibility, and cGMP traceability
Residual host-cell DNA quantitation
Complete solution for extraction and quantitation of host-cell DNA from biopharmaceutical purification sample matrices
Residual plasmid quantitation
Accurate, rapid, and reproducible quantitation of residual plasmid DNA with resDNASEQ Quantitative Plasmid DNA Kit
Adventitious virus testing
Get accurate, rapid results from a system that is part of a total workflow solution and reduce your testing challenges in a GMP environment
AccuSEQ RT-PCR Software
Real-time PCR software that is part of a complete, validated solution for biopharmaceutical contaminant and impurity testing. Designed to help customers meet local regulatory requirements like 21 CFR Part 11 compliance.
Mycoplasma detection testing
Help ensure early detection of mycoplasma contamination and same day actionable results, with a sensitive real-time PCR based mycoplasma detection assay
Microbial identification
Rapid, accurate identification of thousands of bacterial and fungal species typically in under 5 hours
Purity test with SEC-HPLC
Separate biological molecules and polymers according to size using either SDS-PAGE / SEC-HPLC / capillary electrophoresis (reduced & nonreduced)
Sample preparation
A universal, magnetic bead-based sample preparation technology for efficient sample clean up for reproducible contaminant and impurity testing
Stability testing environmental chambers
Achieve testing consistency and regulatory compliance with temperature uniformity and stability
Solutions to enable a robust biotech commercialization strategy
Opening a new lab space?
Simplify your new lab set-up: our Jump Start program can help you design your lab with the products that will set you up for success, all with special discounts.
Essential lab equipment
Simplify processes and enable discovery with our innovative laboratory equipment—the essential infrastructure of science.
Scale-up solutions
Solutions for Biotech scale up to accommodate more samples, more data, and higher production.
Essential lab consumables
Simplify processes and enable discovery with our innovative laboratory consumables—the essential infrastructure of science.
Outsourcing services
No capacity, time, or resources to handle a project in-house? Outsource it to us and our staff of experts will handle the project for you.
Service and support packages
There’s no time for downtime in your lab, our services and support packages keep your lab up and running.
OEM & commercial supply
Customization, security of supply, quality, and expertise are values beyond the products and services when you partner with us.
Resources for navigating vaccine development processes
At the dawn of the era of precision medicine, researchers are finding new ways to develop cost-effective vaccines that target everything from viruses to cancer, using a diverse set of starting materials. From live-attenuated and inactivated to recombinant and toxoid to cutting-edge DNA vaccines, the global need for improved health outcomes is driving endless possibilities for vaccine development.
See our resources for vaccine research and development:
The Future of Vaccine Development infographic
Understanding the history of vaccine development can help to accelerate the creation of future innovations efficiently and safely. Download our infographic to learn more about common challenges in vaccine development and key considerations at each stage of the workflow.
Navigating challenges in vaccine development article
Developing a safe and effective vaccine can be an uphill battle for biotech companies with pathogens constantly evolving, regulatory challenges, and tight timelines. Read our article to learn how novel technologies can help researchers to transverse challenges during research and development.
How to scale up and meet future healthcare needs
For many companies, COVID-19 exposed gaps and weaknesses in critical processes preventing their ability to quickly adapt or scale. In this article, we discuss ways of creating efficiencies across the pipeline to improve processes and accelerate time-to-market.
Products and services for every stage of vaccine development
From the identification, synthesis, and optimization of targets to vaccine production, delivery, and testing, Thermo Fisher Scientific provides an unparalleled array of reliable and scalable solutions and services to help you accelerate productivity across the stages of vaccine development.
Podcast: The power of transient protein expression in vaccine development
Listen to Dr. Henry Chiou, Director of Protein and Viral Expression Systems and Transfection at Thermo Fisher Scientific, discuss how transient protein expression systems offer speed and flexibility to move candidates into clinical trials with the highest chance of success.
Repertoire convergence and its impact on vaccine research and development
Studying convergence and obtaining a deeper understanding of immune response may help improve vaccine efficacy. Read our article to learn more about convergence and the technologies that can assist researchers in studying it.
For Research Use Only. Not for use in diagnostic procedures.
Style Sheet for Global Design System