E-Gel Electrophoresis System | Thermo Fisher Scientific

E-Gel Power Snap Systems are compact benchtop instruments that have integrated nucleic acid electrophoresis and gel imaging functionalities. The instrument has two main components: the instrument device base and the camera to capture gel images. The instrument works with precast E-Gel agarose gels, which are buffer-less gels containing SYBR safe DNA stains, and ladders. This eliminates the need to pour gels, prepare buffers, and handle toxic dyes such as ethidium bromide.

The components of the E-Gel Power Snap systems are designed to save time and streamline the nucleic acid electrophoresis workflow. This system facilitates a simple three-step workflow: load, run, and analyze (Figure 1).

Watch video: E-Gel Power Snap Plus System

Load—With precast Invitrogen E-Gel cassettes, mixing and pouring gels is unnecessary
Run—Select a preprogrammed protocol on the intuitive touchscreen interface
Analyze—View results in real time using the camera. Print and transfer results for further analysis*

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A panel of three photographs showing Load, Run, and Analyze steps

Figure 1. Three-step workflow of E-Gel electrophoresis systems

Advantages of E-Gel electrophoresis device and imaging systems

The two models of the E-Gel Precast Agarose Gel Electrophoresis Systems, including the Power Snap and Power Snap Plus, offer flexible sample throughputs and are upgrades over historical gel analyzers and E-Gel imagers, allowing faster setup, gel runs, and analysis. Both systems include:

Real-time visualization: Amber filter to monitor real-time sample migration
Sample safety: Blue-light transilluminator does not damage DNA samples
Intuitive interface: Easy operation with user-friendly touch screen and preset protocols
Flexible throughput: Gels with 11-, 22-, 48-, and 96-wells can be run (model-dependent)
High resolution camera for image capture, with image editing capabilities
Internal storage: Up to 3 months of experimental data can be stored in the device
Small footprint: 6x smaller than traditional gel documentation systems

E-Gel Power Snap Systems: A comparison

	E-Gel Power Snap Plus Electrophoresis System	E-Gel Power Snap Electrophoresis System

Video overview	Watch now	Watch now
Virtual tour	View now	View now
Capability overview	Flexible, high resolution DNA screening; suitable for both high- and low-throughput DNA gel imaging and analysis.	For routine DNA and RNA electrophoresis; suitable for running 11- to 22-well precast agarose gels.
E-Gel agarose gel compatibility	11-, 22-, 48-, and 96-wells*, CloneWell II and SizeSelect II gels with adaptor	11- and 22-wells, CloneWell II and SizeSelect II gels
Camera resolution	13 MP	3 MP
Image storage	64 GB	32 GB
Cloud enabled	Yes	No
iBright Analysis Software compatible	Yes	No
Instrument dimensions (L x W x H)	29.1 x 22.0 x 10.1 cm	23.3 x 21.0 x 7.0 cm
Camera dimensions (L x W x H)	23.3 x 21.0 x 22.8 cm	26 x 13 x 15 cm
Printer compatible	Yes, Sony UP-X898MD thermal printer	No

*Contains additional wells for marker lanes

E-Gel Power Snap Plus Electrophoresis System

Instrument options and pricing

Maintain productivity with extended warranties
Rapid Exchange (REX) one-year extended warranties are available (at an additional charge) for both the E-Gel Power Snap Plus device and camera. If your instrument needs repair, just call our support center and we will exchange your instrument for a factory-certified, refurbished replacement instrument within one business day from the time we determine a replacement is required. Replacement instruments are typically received within three days of shipment and are yours to keep. All parts, labor, and shipping charges are included, and existing warranty contracts will be transferred to replacement units.

Videos

E-Gel Power Snap Plus System

Learn how to perform high throughput gel electrophoresis, monitor DNA migration, and capture gel images with the E-Gel Power Snap Plus System. Find out about the image editing and image storage options.

E-Gel Power Snap Plus How-to: Deconvolution Overview

Discover the unique features of the Power Snap Plus E-Gel system, including how to easily read results with on‑instrument deconvolution and analysis for Invitrogen E-Gel 96-well gels.

E-Gel Power Snap Electrophoresis System

Instrument options and pricing

Videos

Invitrogen E-Gel Power Snap System overview

Simplify electrophoresis with the Invitrogen E-Gel Power Snap System, the platform that integrates gel running and imaging functions. Watch to learn the benefits of the E-Gel Power Snap Electrophoresis System.

Invitrogen E-Gel Power Snap System features

Explore the features of the E-Gel Power Snap Electrophoresis System including the gel image capture and editing functions.

How to quickly purify DNA with E-Gel CloneWell II precast gels

Watch a demo of how to gel purify DNA using the E-Gel Power Snap System and E-Gel CloneWell II gel. Load samples, run the gel, capture bands of interest in the recovery well, and pipette out purified DNA bands. No additional purification steps needed.

How to perform rapid electrophoresis using an E-Gel Power Snap device and E-Gel EX Cassette

Watch a demo of agarose gel electrophoresis using an E-Gel Power Snap System and E-Gel EX Cassette. The ease and simplicity of the process is ideal for research labs.

Image analysis

Image analysis software and upgrades

iBright Image Analysis Software analyzes data from E-Gel images captured by the integrated camera. The gel images and the results of data analysis can be stored on Thermo Fisher’s Connect Platform. iBright Image Analysis is included in the E-Gel Power Snap Plus Electrophoresis System.

Learn more about iBright Image Analysis Software

The E-Gel Power Snap Plus System firmware is periodically updated with fixes and new and enhanced features to offer a rich user experience.

Keep up-to-date on firmware upgrades

E-Gel precast gel electrophoresis systems

See all the benefits of the innovative, fast, and buffer-less system in one place.

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Invitrogen E-Gel products to complete your gel electrophoresis system

For best results, the E-Gel Power Snap and Power Snap Plus System must be used in conjunction with other Invitrogen E-Gel line of products, which include:

Invitrogen E-Gel precast agarose gels

E-Gel Precast Agarose Gels are ideal for fast and convenient results of DNA and RNA fragments and are available in a variety of percentages and well formats.

Explore E-Gel precast gels

A product image of the Invitrogen E-Gel DNA Ladder reagents.

Invitrogen E-Gel DNA ladders and loading buffers

E-Gel DNA ladders and loading buffer are formulated for optimal performance on E-Gel precast agarose gels.

Explore E-Gel ladders and loading buffer

Application notes and manuals

Application note: Simple and fast genotyping workflow
Application note: RT-LAMP of potato spindle tuber viroid RNA using SuperScript IV RT-LAMP Master Mix
Application note: Using SuperScript IV RT-LAMP Master Mix to detect DNA from fungal and fungus-like plant pathogens
Application note: RT-LAMP of clinical SARS-CoV-2 RNA using SuperScript IV RT-LAMP Master Mix
Application note: Successful amplification of AT-rich DNA sequences with Platinum SuperFi II DNA Polymerase
User guide: User guide: E‑Gel Power Snap Plus Electrophoresis System

Resources

Invitrogen E-Gel Power Snap Electrophoresis Systems