Zeba Desalting Products

Thermo Scientific Zeba desalting products are widely used in various research applications that involve the separation of proteins, and other macromolecules from soluble low molecular weight substances (e.g., salts) that may adversely impact the stability of the analytes or interfere with downstream applications. Zeba Desalting products are also used in protein solution buffer exchange protocols for the generation of more appropriate buffers before subsequent applications such as western blotting, immunoprecipitation, activity assays, and mass spectrometry.

Zeba Desalting products yield exceptional desalting and protein-recovery characteristics and provide consistent performance over a wide range of sample sizes and protein concentrations. These desalting products speed up the desalting process by eliminating the time needed for samples to drop out of gravity flow columns. They offer a fast and efficient protocol for the collection and concentration of clean samples in one fraction, require no chromatography system, and permit multi-sample processing.

Choose the desalting product for your experiment ›

Zeba desalting products rely on gel filtration chromatography, where different molecular weight cut-off (MWCO) limits exclude molecules based on size. Compared with dialysis, this technology offers the advantages of speed, compatibility with organic and other solvents, and the ability to concentrate contaminating material down to a relatively small volume, which is useful for work with toxic/radioactive substances.