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Define your DSAs with greater confidence
The powerful next step for HLA donor specific antibody (DSA) testing is available with the Thermo Scientific LABScreen Single Antigen ExPlex Assay.
Building on the trusted LABScreen Single Antigen platform, the ExPlex panel offers extended HLA Antibody coverage with an additional 54 Class I and 24 Class II single antigens. With the option and ability to combine with the original panel on the Thermo Scientific LABScan3D instrument, the ExPlex kit provides cutting-edge capabilities with a total of 151 Class I and 119 Class II Common and Well-Documented alleles in a single well-set up.
These increased specificities may provide broader antibody data to evaluate eplet patterns and complement your molecular donor typing results.
How it works
Simple workflow with a single-well setup
This solid-phase assay applies bead-based multiplexing to deliver broader data for advanced analytics, all in one well using the familiar Single Antigen workflow!
Assay coverage
With these Luminex beads, you can expand your allele coverage to 151 Class I or 119 Class II CWD alleles.
HLA Class I – 54 additional single antigens
| HLA-A | ||
|---|---|---|
| A*01:02 | A*02:10 | A*26:02 |
| A*02:05 | A*02:18 | A*26:03 |
| A*02:07 | A*03:02 | |
| HLA-B | ||
| B*07:14 | B*27:06 | B*40:03 |
| B*15:04 | B*35:02 | B*40:04 |
| B*15:06 | B*35:03 | B*40:05 |
| B*15:07 | B*35:08 | B*41:02 |
| B*15:17 | B*35:12 | B*42:02 |
| B*15:18 | B*38:02 | B*48:02 |
| B*15:20 | B*39:02 | B*50:02 |
| B*15:21 | B*39:04 | B*55:02 |
| B*15:24 | B*39:05 | B*55:04 |
| B*15:27 | B*39:06 | B*56:03 |
| B*27:04 | B*39:13 | |
| HLA-C | ||
| C*01:03 | C*08:02 | C*15:05 |
| C*02:10 | C*08:03 | C*16:02 |
| C*04:03 | C*08:04 | C*17:03 |
| C*07:01 | C*12:02 | C*18:01 |
| C*07:04 | C*14:03 | |
HLA Class II – 24 additional single antigens
| HLA-DR | ||
|---|---|---|
| DRB1*04:06 | DRB1*08:07 | DRB3*02:01 |
| DRB1*04:07 | DRB1*13:02 | DRB5*01:02 |
| DRB1*04:10 | DRB1*14:04 | |
| DRB1*04:11 | DRB1*14:05 | |
| DRB1*08:02 | DRB1*14:06 | |
| DRB1*08:03 | DRB1*14:03 | |
| HLA-DQ | ||
| DQB1*03:19 - DQA1*02:01 | DQB1*05:03 - DQA1*01:01 | |
| HLA-DP | ||
| DPB1*02:02 - DPA1*01:03 | DPB1*40:01 - DPA1*01:05 | |
| DPB1*26:01 - DPA1*03:01 | DPB1*85:01 - DPA1*01:03 | |
| DPB1*30:01 - DPA1*02:01 | DPB1*105:01 - DPA1*02:01 | |
| DPB1*31:01 - DPA1*03:01 | DPB1*107:01 - DPA1*02:01 | |
Not all products are CE marked or have 510(k) clearance for sale in the U.S. Availability of products in each country depends on local regulatory marketing authorization status.