Browse bone biology pathways

Bones are an important tissue, providing support for the body, protecting organs, producing blood cells, and storing minerals. Several pathways are involved in bone development and growth as well as bone remodeling, including the BMP and RANK pathways.

BMP Pathway

Bone morphogenetic proteins (BMPs) are a large subclass of the transforming growth factor-beta (TGF-beta) superfamily.

RANK Pathway

RANKL and its receptor RANK are key regulators of bone remodeling, and are essential for the development and activation of osteoclasts.

RANK Signaling in Osteoclasts

RANKL induces the differentiation of osteoclast precursor cells and stimulates the resorption function and survival of mature osteoclasts.

Antibodies Resource Library

Access a targeted collection of scientific application notes, methods, and cell signaling charts.