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CellModel Services — Stem Cell Characterization
A challenging and often tedious aspect of stem cell research is the need to characterize cells throughout your experiments. Confirming cell identity, pluripotency, gene expression, and other characteristics of stem cells requires a broad set of tools and the expertise to know what to look for in each test.
With access to a complete portfolio of characterization tools and cutting-edge instruments, the CellModel Services team can perform numerous stem cell characterization experiments using cell lines that you provide or ones that we customize for you.
Stem cell characterization services
Characterization services can be provided as a stand-alone service or added to any CellModel Services reprogramming, differentiation, or assay development project.
Genomic analysis
A range of characterization services on genomic analysis are available to confirm normal karyotype, monitor genomic variation, and confirm cell identity.
Our KaryoStat+ Karyotyping Service is a fast and cost-effective alternative to typical G-banded karyotyping that leverages the array-based CytoScan HT-CMA 96F Assay Kit, offering whole-genome coverage for accurate detection of chromosomal aberrations.
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The KaryoStat+ with Cell Identification service leverages the KaryoStat assay to offer accurate detection of chromosomal aberrations and DNA fingerprint-based matching of human cell lines through analysis and correlation of 150k SNPs across the whole genome.
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Oncomine Service is used for the monitoring of genomic variations associated with select cancer hotspots in iPSC samples. The service leverages the Ion Torrent OncomineComprehensive Assay v3M to enable analysis of variants across 161 genes, offering higher detection sensitivity from the next-generation sequencing platform and results in 4 weeks.
Learn more about the new Oncomine service today
Pluripotency services
The following are characterization services we offer for the assessment of pluripotency of your stem cell culture.
Our PluriTest Characterization Service can provide analysis and process the transcriptome of samples against an extensive and well-characterized reference set of previously characterized cell and tissue by leveraging our PrimeView Global Gene Expression Profile Assays in combination with the PluriTest bioinformatics tool.
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Learn more about how researchers use the cost-effective TaqMan hPSC Scorecard Panel to enable verification of pluripotency and determination of lineage bias for both embryonic and induced pluripotent stem cell lines.
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Sterility testing
Confirming the sterility of your stem cell culture is a critical step for your research.
Our Mycoplasma Detection Service is used to detect Mycoplasma contamination. The service leverages the Applied Biosystems MycoSEQ Mycoplasma qPCR Detection Kit to detect over 90 Mycoplasma species, offering the sensitivity to detect less than 10 copies per reaction and results in less than 3 weeks. Add the Mycoplasma service on to your current characterization service request.
Learn more
Genomic analysis
A range of characterization services on genomic analysis are available to confirm normal karyotype, monitor genomic variation, and confirm cell identity.
Our KaryoStat+ Karyotyping Service is a fast and cost-effective alternative to typical G-banded karyotyping that leverages the array-based CytoScan HT-CMA 96F Assay Kit, offering whole-genome coverage for accurate detection of chromosomal aberrations.
Learn more
The KaryoStat+ with Cell Identification service leverages the KaryoStat assay to offer accurate detection of chromosomal aberrations and DNA fingerprint-based matching of human cell lines through analysis and correlation of 150k SNPs across the whole genome.
Learn more
Oncomine Service is used for the monitoring of genomic variations associated with select cancer hotspots in iPSC samples. The service leverages the Ion Torrent OncomineComprehensive Assay v3M to enable analysis of variants across 161 genes, offering higher detection sensitivity from the next-generation sequencing platform and results in 4 weeks.
Learn more about the new Oncomine service today
Pluripotency services
The following are characterization services we offer for the assessment of pluripotency of your stem cell culture.
Our PluriTest Characterization Service can provide analysis and process the transcriptome of samples against an extensive and well-characterized reference set of previously characterized cell and tissue by leveraging our PrimeView Global Gene Expression Profile Assays in combination with the PluriTest bioinformatics tool.
Learn more
Learn more about how researchers use the cost-effective TaqMan hPSC Scorecard Panel to enable verification of pluripotency and determination of lineage bias for both embryonic and induced pluripotent stem cell lines.
Learn more
Sterility testing
Confirming the sterility of your stem cell culture is a critical step for your research.
Our Mycoplasma Detection Service is used to detect Mycoplasma contamination. The service leverages the Applied Biosystems MycoSEQ Mycoplasma qPCR Detection Kit to detect over 90 Mycoplasma species, offering the sensitivity to detect less than 10 copies per reaction and results in less than 3 weeks. Add the Mycoplasma service on to your current characterization service request.
Learn more
Ordering information
Characterization services can be provided as a stand-alone service or added to any CellModel Services reprogramming, differentiation, or assay development project.
| Services available | Life Technologies tools utilized |
|---|---|
| Immunocytochemistry for pluripotency | Floid Cell Imaging Station |
| Fluorescent activated cell sorting for pluripotency | Attune Acoustic Focusing Cytometer |
| Germ layer characterization / embryoid body formation | FLoid Cell Imaging Station |
| Cell identity confirmation | AuthentiFiler PCR Amplification Kit |
| Gene expression analysis | Taqman Gene Expression Kits QuantStudio 12K Flex Real-Time PCR System |
Targeted genomic sequencing (AmpliSeq kits) | Ion Personal Genome Machine (PGM) System |
Contact us today to discuss your stem cell characterization requirements with a technical specialist.
Featured video
Thermo Fisher Cell Biology Services Characterization
A short video describing our service capabilities around characterization for stem cell customers.
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