Product References
TGFβ1+CCR5+ neutrophil subset increases in bone marrow and causes age-related osteoporosis in male mice.
Nature communications
Li J,Yao Z,Liu X,Duan R,Yi X,Ayoub A,Sanders JO,Mesfin A,Xing L,Boyce BF
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Wed Jan 11 00:00:00 EST 2023
Sympathetic Nerves Coordinate Corneal Epithelial Wound Healing by Controlling the Mobilization of Ly6Chi Monocytes From the Spleen to the Injured Cornea.
Investigative ophthalmology & visual science
He S,Liu J,Xue Y,Fu T,Li Z
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2023
Intranasal Delivery of Endothelial Cell-Derived Extracellular Vesicles with Supramolecular Gel Attenuates Myocardial Ischemia-Reperfusion Injury.
International journal of nanomedicine
Wang J,Tan Y,Dai Y,Hu K,Tan X,Jiang S,Li G,Zhang X,Kang L,Wang X,Xu B
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Thu Oct 05 00:00:00 EDT 2023
Monocytes reprogrammed by tumor microparticle vaccine inhibit tumorigenesis and tumor development.
Cancer nanotechnology
Sun W,Dai L,Cao Y,Pan P,Zhi L,Wang X,Yuan X,Gao Z,Guo S,Liu G,Yin J,Xie L,Wang L,Wang Y,Li W,Li H,Jia Y
17-5932-82 was used in Flow cytometry/Cell sorting to provide novel vaccination strategy for the development of tumor vaccines and facilitate the application of T-MPs for clinic oncotherapy.
Tue Apr 25 00:00:00 EDT 2023
Monocytes reprogrammed by tumor microparticle vaccine inhibit tumorigenesis and tumor development.
Cancer nanotechnology
Sun W,Dai L,Cao Y,Pan P,Zhi L,Wang X,Yuan X,Gao Z,Guo S,Liu G,Yin J,Xie L,Wang L,Wang Y,Li W,Li H,Jia Y
17-5932-82 was used in Flow cytometry/Cell sorting to provide novel vaccination strategy for the development of tumor vaccines and facilitate the application of T-MPs for clinic oncotherapy.
Tue Apr 25 00:00:00 EDT 2023
Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE.
Nature
Pernet E,Sun S,Sarden N,Gona S,Nguyen A,Khan N,Mawhinney M,Tran KA,Chronopoulos J,Amberkar D,Sadeghi M,Grant A,Wali S,Prevel R,Ding J,Martin JG,Thanabalasuriar A,Yipp BG,Barreiro LB,Divangahi M
17-5932-82 was used in Flow cytometry/Cell sorting to highlight the complexity of prenatal RTM programming and reveal their dependency on in trans eicosanoid production by neutrophils for lifelong self-renewal.
Wed Feb 01 00:00:00 EST 2023
Macrophagic AMPKα1 orchestrates regenerative inflammation induced by glucocorticoids.
EMBO reports
Caratti G,Desgeorges T,Juban G,Stifel U,Fessard A,Koenen M,Caratti B,Théret M,Skurk C,Chazaud B,Tuckermann JP,Mounier R
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Mon Feb 06 00:00:00 EST 2023
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
NLRP3 in tumor-associated macrophages predicts a poor prognosis and promotes tumor growth in head and neck squamous cell carcinoma.
Cancer immunology, immunotherapy : CII
Chen L,Wan SC,Mao L,Huang CF,Bu LL,Sun ZJ
17-5932-82 was used in Flow cytometry/Cell sorting to find that NLRP3 was highly expressed in tumor-associated macrophages (TAMs) in both mouse and human HNSCC, and the expression of NLRP3 was positively correlated with the density of TAMs according to immunohistochemistry, immunofluorescence, and flow cytometry analyses.
Thu Jun 01 00:00:00 EDT 2023
The NKCC1 ion transporter modulates microglial phenotype and inflammatory response to brain injury in a cell-autonomous manner.
PLoS biology
Tóth K,Lénárt N,Berki P,Fekete R,Szabadits E,Pósfai B,Cserép C,Alatshan A,Benkő S,Kiss D,Hübner CA,Gulyás A,Kaila K,Környei Z,Dénes Á
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2022
Mesenchymal stromal cells equipped by IFNα empower T cells with potent anti-tumor immunity.
Oncogene
Zhang T,Wang Y,Li Q,Lin L,Xu C,Xue Y,Hu M,Shi Y,Wang Y
17-5932-82 was used in Flow Cytometry to conclude that IFNα-MSCs represent a novel tumor immunotherapy strategy, especially when combined with PD-L1 blockade.
Tue Mar 01 00:00:00 EST 2022
Gene-dosage effect of Pfkfb3 on monocyte/macrophage biology in atherosclerosis.
British journal of pharmacology
Guo S,Li A,Fu X,Li Z,Cao K,Song M,Huang S,Li Z,Yan J,Wang L,Dai X,Feng D,Wang Y,He J,Huo Y,Xu Y
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2022
Mineralocorticoid receptor antagonists and glucocorticoids differentially affect skeletal muscle inflammation and pathology in muscular dystrophy.
JCI insight
Howard ZM,Gomatam CK,Rabolli CP,Lowe J,Piepho AB,Bansal SS,Accornero F,Rafael-Fortney JA
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Mon Oct 10 00:00:00 EDT 2022
Therapeutic CFTR Correction Normalizes Systemic and Lung-Specific S1P Level Alterations Associated with Heart Failure.
International journal of molecular sciences
Uhl FE,Vanherle L,Matthes F,Meissner A
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Fri Jan 14 00:00:00 EST 2022
BECN2 (beclin 2) Negatively Regulates Inflammasome Sensors Through ATG9A-Dependent but ATG16L1- and LC3-Independent Non-Canonical Autophagy.
Autophagy
Deng G,Li C,Chen L,Xing C,Fu C,Qian C,Liu X,Wang HY,Zhu M,Wang RF
17-5932-82 was used in Flow cytometry/Cell sorting to study the role of beclin 2 on regulation of inflammasome sensors.
Tue Feb 01 00:00:00 EST 2022
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression.
Nature communications
Qi M,Xia Y,Wu Y,Zhang Z,Wang X,Lu L,Dai C,Song Y,Xu K,Ji W,Zhan L
17-5932-82 was used in Flow Cytometry to demonstrate that Lin28B promotes lung metastasis of breast cancer by building an immune-suppressive pre-metastatic niche.
Wed Feb 16 00:00:00 EST 2022
A novel ZsGreen knock-in melanoma cell line reveals the function of CD11b in tumor phagocytosis.
Immunology and cell biology
Zhang L,Feng X,Shen Y,Wang Y,Liu Z,Ma Y,Gu Y,Guo G,Duan L,Lu L,Liang Y,Lawrence T,Huang R
17-5932-82 was used in Flow cytometry/Cell sorting to demonstrate that the ZsGreen-expressing YUMM1.7 melanoma model provides a valuable tool for the study of phagocytosis in vivo.
Sat Oct 01 00:00:00 EDT 2022
Environmental eustress improves postinfarction cardiac repair via enhancing cardiac macrophage survival.
Science advances
Bai PY,Chen SQ,Jia DL,Pan LH,Liu CB,Liu J,Luo W,Yang Y,Sun MY,Wan NF,Rong WW,Sun AJ,Ge JB
17-5932-82 was used in Flow cytometry/Cell sorting to demonstrate that EE optimizes postinfarction cardiac repair and highlights the significance of EE as a previously unidentified strategy for impeding adverse ventricular remodeling.
Fri Apr 29 00:00:00 EDT 2022
Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells.
Immunity
Shmuel-Galia L,Humphries F,Lei X,Ceglia S,Wilson R,Jiang Z,Ketelut-Carneiro N,Foley SE,Pechhold S,Houghton J,Muneeruddin K,Shaffer SA,McCormick BA,Reboldi A,Ward D,Marshak-Rothstein A,Fitzgerald KA
17-5932-82 was used in Flow cytometry/Cell sorting to suggest a positive feedback loop wherein dysbiosis foments the accumulation of STING in intestinal myeloid cells, driving intestinal inflammation.
Tue Jun 08 00:00:00 EDT 2021
The deubiquitinase OTUB1 augments NF-κB-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13.
Cellular & molecular immunology
Mulas F,Wang X,Song S,Nishanth G,Yi W,Brunn A,Larsen PK,Isermann B,Kalinke U,Barragan A,Naumann M,Deckert M,Schlüter D
17-5932 was used in Flow cytometry/Cell sorting to reveal that the deubiquitinase OTU domain, ubiquitin aldehyde binding 1 (OTUB1) is upregulated in DCs upon murine Toxoplasma gondii infection and lipopolysaccharide challenge.
Tue Jun 01 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
17-5932-82 was used in Flow Cytometry to show a persistent accumulation of T cells in mice and human autopsy samples for more than 1 mo after stroke.
Mon Aug 02 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
17-5932-82 was used in Flow Cytometry to show a persistent accumulation of T cells in mice and human autopsy samples for more than 1 mo after stroke.
Mon Aug 02 00:00:00 EDT 2021
Pancreatic Cancer Chemotherapy Is Potentiated by Induction of Tertiary Lymphoid Structures in Mice.
Cellular and molecular gastroenterology and hepatology
Delvecchio FR,Fincham REA,Spear S,Clear A,Roy-Luzarraga M,Balkwill FR,Gribben JG,Bombardieri M,Hodivala-Dilke K,Capasso M,Kocher HM
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Mon Mar 28 00:00:00 EDT 2022
Disrupted Iron Metabolism and Mortality during Co-infection with Malaria and an Intestinal Gram-Negative Extracellular Pathogen.
Cell reports
Dos Santos LI,Torres TA,Diniz SQ,Gonçalves R,Caballero-Flores G,Núñez G,Gazzinelli RT,Maloy KJ,Ribeiro do V Antonelli L
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Myeloid DJ-1 deficiency protects acetaminophen-induced acute liver injury through decreasing inflammatory response.
Aging
Wang B,Li J,Jiao J,Xu M,Luo Y,Wang F,Xia Q,Gao Y,Feng Y,Kong X,Sun X
17-5932-82 was used in Flow Cytometry to suggest DJ-1 as a potential therapeutic and/or prophylactic target of APAP-induced acute liver injury.
Wed Jul 21 00:00:00 EDT 2021
Myeloid DJ-1 deficiency protects acetaminophen-induced acute liver injury through decreasing inflammatory response.
Aging
Wang B,Li J,Jiao J,Xu M,Luo Y,Wang F,Xia Q,Gao Y,Feng Y,Kong X,Sun X
17-5932-82 was used in Flow Cytometry to suggest DJ-1 as a potential therapeutic and/or prophylactic target of APAP-induced acute liver injury.
Wed Jul 21 00:00:00 EDT 2021
NOX4 regulates macrophage apoptosis resistance to induce fibrotic progression.
The Journal of biological chemistry
Larson-Casey JL,Gu L,Kang J,Dhyani A,Carter AB
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Thu Jul 01 00:00:00 EDT 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
Abraxane-induced bone marrow CD11b+ myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with 64Cu-labeled anti-CD11b and prevented by anti-CSF-1.
Theranostics
Cao Q,Huang Q,Wang YA,Li C
17-5932-82 was used in Flow Cytometry to conclude that Abraxane-induced bone marrow CD11b+ myeloid cell depletion in tumor-bearing mice could be noninvasively assessed by µPET-CT with 64Cu-αCD11b and prevented by αCSF-1.
Fri Jul 23 00:00:00 EDT 2021
Abraxane-induced bone marrow CD11b+ myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with 64Cu-labeled anti-CD11b and prevented by anti-CSF-1.
Theranostics
Cao Q,Huang Q,Wang YA,Li C
17-5932-82 was used in Flow Cytometry to conclude that Abraxane-induced bone marrow CD11b+ myeloid cell depletion in tumor-bearing mice could be noninvasively assessed by µPET-CT with 64Cu-αCD11b and prevented by αCSF-1.
Fri Jul 23 00:00:00 EDT 2021
Inflammatory resolution and vascular barrier restoration after retinal ischemia reperfusion injury.
Journal of neuroinflammation
Abcouwer SF,Shanmugam S,Muthusamy A,Lin CM,Kong D,Hager H,Liu X,Antonetti DA
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Thu Aug 26 00:00:00 EDT 2021
Roles of lung-recruited monocytes and pulmonary Vascular Endothelial Growth Factor (VEGF) in resolving Ventilator-Induced Lung Injury (VILI).
PloS one
Lin CK,Huang TH,Yang CT,Shi CS
17-5932 was used in Flow cytometry/Cell sorting to identify the phenotypes of monocytes recruited to the lungs during the resolution of VILI and investigated the contributions of monocytes and VEGF to lung repair.
Tue Oct 12 00:00:00 EDT 2021
Roles of lung-recruited monocytes and pulmonary Vascular Endothelial Growth Factor (VEGF) in resolving Ventilator-Induced Lung Injury (VILI).
PloS one
Lin CK,Huang TH,Yang CT,Shi CS
17-5932 was used in Flow cytometry/Cell sorting to identify the phenotypes of monocytes recruited to the lungs during the resolution of VILI and investigated the contributions of monocytes and VEGF to lung repair.
Tue Oct 12 00:00:00 EDT 2021
Plasmacytoid Dendritic Cells and Type I Interferon Promote Extrafollicular B Cell Responses to Extracellular Self-DNA.
Immunity
Soni C,Perez OA,Voss WN,Pucella JN,Serpas L,Mehl J,Ching KL,Goike J,Georgiou G,Ippolito GC,Sisirak V,Reizis B
17-5932-82 was used in Flow Cytometry to establish extrafollicular B cell differentiation into short-lived AFCs as a key mechanism of anti-DNA autoreactivity and reveal a major contribution of pDCs, endosomal Toll-like receptors (TLRs), and IFN-I to this pathway.
Tue Jun 16 00:00:00 EDT 2020
Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair.
Cell stem cell
Shook BA,Wasko RR,Mano O,Rutenberg-Schoenberg M,Rudolph MC,Zirak B,Rivera-Gonzalez GC,López-Giráldez F,Zarini S,Rezza A,Clark DA,Rendl M,Rosenblum MD,Gerstein MB,Horsley V
17-5932-82 was used in Flow Cytometry to identify an essential role for adipocyte lipolysis in regulating inflammation and repair after injury in skin.
Thu Jun 04 00:00:00 EDT 2020
Plaque-associated myeloid cells derive from resident microglia in an Alzheimer's disease model.
The Journal of experimental medicine
Reed-Geaghan EG,Croxford AL,Becher B,Landreth GE
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Mon Apr 06 00:00:00 EDT 2020
Proenkephalin+ regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function.
Proceedings of the National Academy of Sciences of the United States of America
Shime H,Odanaka M,Tsuiji M,Matoba T,Imai M,Yasumizu Y,Uraki R,Minohara K,Watanabe M,Bonito AJ,Fukuyama H,Ohkura N,Sakaguchi S,Morita A,Yamazaki S
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Tue Aug 25 00:00:00 EDT 2020
IgE Contributes to Atherosclerosis and Obesity by Affecting Macrophage Polarization, Macrophage Protein Network, and Foam Cell Formation.
Arteriosclerosis, thrombosis, and vascular biology
Zhang X,Li J,Luo S,Wang M,Huang Q,Deng Z,de Febbo C,Daoui A,Liew PX,Sukhova GK,Metso J,Jauhiainen M,Shi GP,Guo J
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2020
Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.
British journal of pharmacology
De Cicco P,Ercolano G,Rubino V,Terrazzano G,Ruggiero G,Cirino G,Ianaro A
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
Characterization and regulation of osteoclast precursors following chronic Porphyromonas gingivalis infection.
Journal of leukocyte biology
Zhao Y,Li Z,Su L,Ballesteros-Tato A,Katz J,Michalek SM,Feng X,Zhang P
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Antitumor Effect and Immune Response of Nanosecond Pulsed Electric Fields in Pancreatic Cancer.
Frontiers in oncology
Zhao J,Chen S,Zhu L,Zhang L,Liu J,Xu D,Tian G,Jiang T
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Fri Oct 28 00:00:00 EDT 2022
Divergent effects of genetic and pharmacological inhibition of Nox2 NADPH oxidase on insulin resistance-related vascular damage.
American journal of physiology. Cell physiology
Maqbool A,Watt NT,Haywood N,Viswambharan H,Skromna A,Makava N,Visnagri A,Shawer HM,Bridge K,Muminov SK,Griffin K,Beech DJ,Wheatcroft SB,Porter KE,Simmons KJ,Sukumar P,Shah AM,Cubbon RM,Kearney MT,Yuldasheva NY
17-5932 was used in Flow cytometry/Cell sorting to demonstrate that insulin resistance is characterized by increased Nox2-derived vascular superoxide.
Wed Jul 01 00:00:00 EDT 2020
Effects of Hypertonic Saline and Hydroxyethyl Starch on Myeloid-Derived Suppressor Cells in Hemorrhagic Shock Mice under Secondary Bacterial Attack.
BioMed research international
Jiang JK,Hong LJ,Lu YQ
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
Site-1 protease ablation in the osterix-lineage in mice results in bone marrow neutrophilia and hematopoietic stem cell alterations.
Biology open
Patra D,Kim J,Zhang Q,Tycksen E,Sandell LJ
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Tue Jun 23 00:00:00 EDT 2020
The impact of Clonorchis sinensis infection on immune response in mice with type II collagen-induced arthritis.
BMC immunology
Li X,Yang Y,Qin S,Kong F,Yan C,Cheng W,Pan W,Yu Q,Hua H,Zheng K,Tang R
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Mon Feb 17 00:00:00 EST 2020
GDF3 Protects Mice against Sepsis-Induced Cardiac Dysfunction and Mortality by Suppression of Macrophage Pro-Inflammatory Phenotype.
Cells
Wang L,Li Y,Wang X,Wang P,Essandoh K,Cui S,Huang W,Mu X,Liu Z,Wang Y,Peng T,Fan GC
17-5932-82 was used in Flow Cytometry to show that serum GDF3 levels in septic patients are elevated and strongly correlate with severity of sepsis and 28-day mortality.
Fri Jan 03 00:00:00 EST 2020
GDF3 Protects Mice against Sepsis-Induced Cardiac Dysfunction and Mortality by Suppression of Macrophage Pro-Inflammatory Phenotype.
Cells
Wang L,Li Y,Wang X,Wang P,Essandoh K,Cui S,Huang W,Mu X,Liu Z,Wang Y,Peng T,Fan GC
17-5932-82 was used in Flow Cytometry to show that serum GDF3 levels in septic patients are elevated and strongly correlate with severity of sepsis and 28-day mortality.
Fri Jan 03 00:00:00 EST 2020
The Transcription Factor Nfix Requires RhoA-ROCK1 Dependent Phagocytosis to Mediate Macrophage Skewing during Skeletal Muscle Regeneration.
Cells
Saclier M,Lapi M,Bonfanti C,Rossi G,Antonini S,Messina G
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Fri Mar 13 00:00:00 EDT 2020
Extracellular miR-146a-5p Induces Cardiac Innate Immune Response and Cardiomyocyte Dysfunction.
ImmunoHorizons
Shimada BK,Yang Y,Zhu J,Wang S,Suen A,Kronstadt SM,Jeyaram A,Jay SM,Zou L,Chao W
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Mon Sep 21 00:00:00 EDT 2020
Resident macrophages acquire innate immune memory in staphylococcal skin infection.
eLife
Feuerstein R,Forde AJ,Lohrmann F,Kolter J,Ramirez NJ,Zimmermann J,Gomez de Agüero M,Henneke P
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Wed Jul 08 00:00:00 EDT 2020
Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway.
eLife
Kim EH,Woodruff MC,Grigoryan L,Maier B,Lee SH,Mandal P,Cortese M,Natrajan MS,Ravindran R,Ma H,Merad M,Gitlin AD,Mocarski ES,Jacob J,Pulendran B
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Tue Jun 09 00:00:00 EDT 2020
Gasdermin D in macrophages restrains colitis by controlling cGAS-mediated inflammation.
Science advances
Ma C,Yang D,Wang B,Wu C,Wu Y,Li S,Liu X,Lassen K,Dai L,Yang S
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Host Cathelicidin Exacerbates Group B Streptococcus Urinary Tract Infection.
mSphere
Patras KA,Coady A,Babu P,Shing SR,Ha AD,Rooholfada E,Brandt SL,Geriak M,Gallo RL,Nizet V
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Wed Apr 22 00:00:00 EDT 2020
IGFBP-1 in Cardiometabolic Pathophysiology-Insights From Loss-of-Function and Gain-of-Function Studies in Male Mice.
Journal of the Endocrine Society
Haywood NJ,Slater TA,Drozd M,Warmke N,Matthews C,Cordell PA,Smith J,Rainford J,Cheema H,Maher C,Bridge KI,Yuldasheva NY,Cubbon RM,Kearney MT,Wheatcroft SB
17-5932-82 was used in Flow Cytometry to provide new insights into the role of IGFBP-1 in metabolic and vascular pathophysiology.
Wed Jan 01 00:00:00 EST 2020
Prodrug-Loaded Zirconium Carbide Nanosheets as a Novel Biophotonic Nanoplatform for Effective Treatment of Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Liu Q,Xie Z,Qiu M,Shim I,Yang Y,Xie S,Yang Q,Wang D,Chen S,Fan T,Ding B,Guo Z,Adah D,Yao X,Zhang Y,Wu H,Wu Z,Wei C,Wang H,Kim HS,Zou Q,Yan Q,Cai Z,Kim JS,Liu LP,Zhang H,Cao Y
17-5932-82 was used in Flow Cytometry to unravel a promising biphotonic strategy for precision treatment of cancer.
Tue Dec 01 00:00:00 EST 2020
MicroRNA-99a mimics inhibit M1 macrophage phenotype and adipose tissue inflammation by targeting TNFα.
Cellular & molecular immunology
Jaiswal A,Reddy SS,Maurya M,Maurya P,Barthwal MK
17-5932 was used in Flow cytometry/Cell sorting to study the influence of miR-99a on macrophage phenotype and tissue inflammation.
Wed May 01 00:00:00 EDT 2019
A maresin 1/RORα/12-lipoxygenase autoregulatory circuit prevents inflammation and progression of nonalcoholic steatohepatitis.
The Journal of clinical investigation
Han YH,Shin KO,Kim JY,Khadka DB,Kim HJ,Lee YM,Cho WJ,Cha JY,Lee BJ,Lee MO
17-5932 was used in Flow cytometry/Cell sorting to study the hepatic microenvironments that support the function of RORa as a polarity regulator.
Mon Mar 11 00:00:00 EDT 2019
Oral ferroportin inhibitor ameliorates ineffective erythropoiesis in a model of β-thalassemia.
The Journal of clinical investigation
Manolova V,Nyffenegger N,Flace A,Altermatt P,Varol A,Doucerain C,Sundstrom H,Dürrenberger F
17-5932-82 was used in Flow Cytometry to identified oral ferroportin inhibitors by screening a library of small molecular weight compounds for modulators of ferroportin internalization.
Mon Dec 09 00:00:00 EST 2019
Depression-Induced Neuropeptide Y Secretion Promotes Prostate Cancer Growth by Recruiting Myeloid Cells.
Clinical cancer research : an official journal of the American Association for Cancer Research
Cheng Y,Tang XY,Li YX,Zhao DD,Cao QH,Wu HX,Yang HB,Hao K,Yang Y
17-5932 was used in Flow cytometry/Cell sorting to show that depression promotes myeloid cell infiltration and increases IL6 levels by a sympathetic-NPY signal. Sympathetic-NPY inhibition may be a promising strategy for patients with prostate cancer with high score of psychologic depression.
Mon Apr 15 00:00:00 EDT 2019
Low-Dose Apatinib Optimizes Tumor Microenvironment and Potentiates Antitumor Effect of PD-1/PD-L1 Blockade in Lung Cancer.
Cancer immunology research
Zhao S,Ren S,Jiang T,Zhu B,Li X,Zhao C,Jia Y,Shi J,Zhang L,Liu X,Qiao M,Chen X,Su C,Yu H,Zhou C,Zhang J,Camidge DR,Hirsch FR
17-5932 was used in Flow cytometry/Cell sorting to analyze the impact of apatinib, a smallmolecule VEGFR2-TKI, on the TME in murine Lewis lung carcinoma (LLC) models at different doses alone and in combination with an anti–PD-L1.
Mon Apr 01 00:00:00 EDT 2019
GM-CSF Promotes Antitumor Immunity by Inducing Th9 Cell Responses.
Cancer immunology research
Kim IK,Koh CH,Jeon I,Shin KS,Kang TS,Bae EA,Seo H,Ko HJ,Kim BS,Chung Y,Kang CY
17-5932-82 was used in Flow Cytometry to demonstrate that GM-CSF potentiates the efficacy of cancer vaccines through IL9-producing Th (Th9) cells.
Fri Mar 01 00:00:00 EST 2019
The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis.
Cell reports
Hou X,Chen G,Bracamonte-Baran W,Choi HS,Diny NL,Sung J,Hughes D,Won T,Wood MK,Talor MV,Hackam DJ,Klingel K,Davogustto G,Taegtmeyer H,Coppens I,Barin JG,Čiháková D
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Tue Jul 02 00:00:00 EDT 2019
Regulatory T Cells Control the Switch From in situ to Invasive Breast Cancer.
Frontiers in immunology
Martinez LM,Robila V,Clark NM,Du W,Idowu MO,Rutkowski MR,Bos PD
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2020
Critical Roles of E2F3 in Growth and Musculo-skeletal Phenotype in Mice.
International journal of medical sciences
Kim HR,Rahman FU,Kim KS,Kim EK,Cho SM,Lee K,Moon OS,Seo YW,Yoon WK,Won YS,Kang H,Kim HC,Nam KH
17-5932-82 was used in Flow Cytometry to suggest that E2F3 has a pivotal role in muscle and bone development, and affect normal mouse growth.
Thu Apr 30 00:00:00 EDT 2020
Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by IL-1Ra.
Nature microbiology
Ji DX,Yamashiro LH,Chen KJ,Mukaida N,Kramnik I,Darwin KH,Vance RE
17-5932 was used in Flow cytometry/Cell sorting to show that enhanced production of type I IFNs was responsible for the susceptibility of B6.Sst1S mice to Mycobacterium tuberculosis (Mtb).
Sun Dec 01 00:00:00 EST 2019
Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner.
Cell
Thion MS,Low D,Silvin A,Chen J,Grisel P,Schulte-Schrepping J,Blecher R,Ulas T,Squarzoni P,Hoeffel G,Coulpier F,Siopi E,David FS,Scholz C,Shihui F,Lum J,Amoyo AA,Larbi A,Poidinger M,Buttgereit A,Lledo PM,Greter M,Chan JKY,Amit I,Beyer M,Schultze JL,Schlitzer A,Pettersson S,Ginhoux F,Garel S
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion.
Immunity
Xia P,Wang S,Ye B,Du Y,Li C,Xiong Z,Qu Y,Fan Z
17-5932 was used in Flow cytometry/Cell sorting to study circular RNA-mediated maintenance of hematopoeitic stem cell homeostasis.
Tue Apr 17 00:00:00 EDT 2018
Advanced Glycation End Products Enhance Murine Monocyte Proliferation in Bone Marrow and Prime Them into an Inflammatory Phenotype through MAPK Signaling.
Journal of diabetes research
Jin X,Liu L,Zhang Y,Xiang Y,Yin G,Lu Y,Shi L,Dong J,Shen C
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Wed Oct 10 00:00:00 EDT 2018
Regulated Release of Cryptococcal Polysaccharide Drives Virulence and Suppresses Immune Cell Infiltration into the Central Nervous System.
Infection and immunity
Denham ST,Verma S,Reynolds RC,Worne CL,Daugherty JM,Lane TE,Brown JCS
17-5932 was used in Flow cytometry/Cell sorting to show that exo-glucuronoxylomannan (exo-GXM) performs a different role from capsule GXM during infection, altering cell size and suppressing inflammation.
Thu Mar 01 00:00:00 EST 2018
Antiasthmatic Effects of Sanglong Pingchuan Decoction through Inducing a Balanced Th1/Th2 Immune Response.
Evidence-based complementary and alternative medicine : eCAM
Zhu B,Dong J,Gao X,He Y,Sun H
17-5932 was used in Flow cytometry/Cell sorting to investigate the antiasthmatic effects of Sanglong pingchuan decoction and to explore its mechanisms of action.
Fri Mar 18 00:00:00 EDT 2022
iRhom2-mediated proinflammatory signalling regulates heart repair following myocardial infarction.
JCI insight
Barnette DN,Cahill TJ,Gunadasa-Rohling M,Carr CA,Freeman M,Riley PR
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Thu Feb 08 00:00:00 EST 2018
Differentiated macrophages acquire a pro-inflammatory and cell death-resistant phenotype due to increasing XIAP and p38-mediated inhibition of RipK1.
The Journal of biological chemistry
Rijal D,Ariana A,Wight A,Kim K,Alturki NA,Aamir Z,Ametepe ES,Korneluk RG,Tiedje C,Menon MB,Gaestel M,McComb S,Sad S
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Fri Jul 27 00:00:00 EDT 2018
The Combined Use of Melatonin and an Indoleamine 2,3-Dioxygenase-1 Inhibitor Enhances Vaccine-Induced Protective Cellular Immunity to HPV16-Associated Tumors.
Frontiers in immunology
Moreno ACR,Porchia BFMM,Pagni RL,Souza PDC,Pegoraro R,Rodrigues KB,Barros TB,Aps LRMM,de Araújo EF,Calich VLG,Ferreira LCS
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Thu Sep 19 00:00:00 EDT 2019
AMPK Activation Regulates LTBP4-Dependent TGF-β1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy.
Cell reports
Juban G,Saclier M,Yacoub-Youssef H,Kernou A,Arnold L,Boisson C,Ben Larbi S,Magnan M,Cuvellier S,Théret M,Petrof BJ,Desguerre I,Gondin J,Mounier R,Chazaud B
17-5932 was used in Flow cytometry/Cell sorting to conclude that an AMPK-LTBP4 axis in inflammatory macrophages controls the production of TGF-β1, which is further activated by and acts on fibroblastic cells, leading to fibrosis in DMD.
Tue Nov 20 00:00:00 EST 2018
A Gut Commensal-Produced Metabolite Mediates Colonization Resistance to Salmonella Infection.
Cell host & microbe
Jacobson A,Lam L,Rajendram M,Tamburini F,Honeycutt J,Pham T,Van Treuren W,Pruss K,Stabler SR,Lugo K,Bouley DM,Vilches-Moure JG,Smith M,Sonnenburg JL,Bhatt AS,Huang KC,Monack D
17-5932-82 was used in flow cytometry to provide mechanistic understanding into the role of individualized microbial communities in host-to-host variability of pathogen transmission.
Wed Aug 08 00:00:00 EDT 2018
Mechanical strain determines the site-specific localization of inflammation and tissue damage in arthritis.
Nature communications
Cambré I,Gaublomme D,Burssens A,Jacques P,Schryvers N,De Muynck A,Meuris L,Lambrecht S,Carter S,de Bleser P,Saeys Y,Van Hoorebeke L,Kollias G,Mack M,Simoens P,Lories R,Callewaert N,Schett G,Elewaut D
17-5932 was used in Flow cytometry/Cell sorting to study the role of mechanical strain in controlling site-specific localisation of inflammation and tissue damage in arthritis.
Mon Nov 05 00:00:00 EST 2018
A cell-extrinsic ligand acquired by activated T cells in lymph node can bridge L-selectin and P-selectin.
PloS one
Carlow DA,Tra MC,Ziltener HJ
17-5932 was used in Flow cytometry to examine P-selectin ligand expression on activated CD8+ T cells in murine adoptive transfer models.
Tue Mar 26 00:00:00 EDT 2019
Inhibiting Glycogen Synthase Kinase 3 Reverses Obesity-Induced White Adipose Tissue Inflammation by Regulating Apoptosis Inhibitor of Macrophage/CD5L-Mediated Macrophage Migration.
Arteriosclerosis, thrombosis, and vascular biology
Wang L,Wang Y,Zhang C,Li J,Meng Y,Dou M,Noguchi CT,Di L
17-5932-82 was used in Flow cytometry/Cell sorting to examine the potential mechanism by which GSK3 in modulating obesity-induced visceral adipose tissue (VAT) inflammation.
Sat Sep 01 00:00:00 EDT 2018
Characterization of Multiple Cytokine Combinations and TGF-β on Differentiation and Functions of Myeloid-Derived Suppressor Cells.
International journal of molecular sciences
Lee CR,Lee W,Cho SK,Park SG
17-5932 was used in Flow cytometry/Cell sorting to examine the effect of various cytokine combinations with transforming growth factor-β on myeloid-derived suppressor cells derived from bone marrow cells.
Thu Mar 15 00:00:00 EDT 2018
Peripheral myeloid cells contribute to brain injury in male neonatal mice.
Journal of neuroinflammation
Smith PLP,Mottahedin A,Svedin P,Mohn CJ,Hagberg H,Ek J,Mallard C
17-5932 was used in Flow cytometry/Cell sorting to investigate the role of peripheral myeloid cells in neonatal hypoxic-ischaemic brain injury.
Tue Oct 30 00:00:00 EDT 2018
The G2A Receptor Controls Polarization of Macrophage by Determining Their Localization Within the Inflamed Tissue.
Frontiers in immunology
Kern K,Schäfer SMG,Cohnen J,Pierre S,Osthues T,Tarighi N,Hohmann S,Ferreiros N,Brüne B,Weigert A,Geisslinger G,Sisignano M,Scholich K
17-5932 was used in Flow cytometry to study the role of the G-protein coupled receptor, G2A, in chemotactic migration and polarisation of macrophages, using the zymosan-model of acute inflammation.
Mon Oct 21 00:00:00 EDT 2019
NF-κB c-Rel Is Crucial for the Regulatory T Cell Immune Checkpoint in Cancer.
Cell
Grinberg-Bleyer Y,Oh H,Desrichard A,Bhatt DM,Caron R,Chan TA,Schmid RM,Klein U,Hayden MS,Ghosh S
17-5932-82 was used in Flow cytometry/Cell sorting to understand the mechanisms governing regulatory T cells homeostasis.
Thu Sep 07 00:00:00 EDT 2017
Mir-223 regulates the number and function of myeloid-derived suppressor cells in multiple sclerosis and experimental autoimmune encephalomyelitis.
Acta neuropathologica
Cantoni C,Cignarella F,Ghezzi L,Mikesell B,Bollman B,Berrien-Elliott MM,Ireland AR,Fehniger TA,Wu GF,Piccio L
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
CCR2- and CCR2+ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion.
Mucosal immunology
Liu J,Xue Y,Dong D,Xiao C,Lin C,Wang H,Song F,Fu T,Wang Z,Chen J,Pan H,Li Y,Cai D,Li Z
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2017
Infiltrating Myeloid Cells Exert Protumorigenic Actions via Neutrophil Elastase.
Molecular cancer research : MCR
Lerman I,Garcia-Hernandez ML,Rangel-Moreno J,Chiriboga L,Pan C,Nastiuk KL,Krolewski JJ,Sen A,Hammes SR
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2017
Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression.
Nature communications
Kalkavan H,Sharma P,Kasper S,Helfrich I,Pandyra AA,Gassa A,Virchow I,Flatz L,Brandenburg T,Namineni S,Heikenwalder M,Höchst B,Knolle PA,Wollmann G,von Laer D,Drexler I,Rathbun J,Cannon PM,Scheu S,Bauer J,Chauhan J,Häussinger D,Willimsky G,Löhning M,Schadendorf D,Brandau S,Schuler M,Lang PA,Lang KS
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Loss of IRF2BP2 in Microglia Increases Inflammation and Functional Deficits after Focal Ischemic Brain Injury.
Frontiers in cellular neuroscience
Cruz SA,Hari A,Qin Z,Couture P,Huang H,Lagace DC,Stewart AFR,Chen HH
17-5932 was used in Flow cytometry/Cell sorting to identify that IRF2 binding protein 2 expression in macrophages/microglia is important in limiting inflammation and stroke injury, by mediating the beneficial effect of interferon beta.
Thu Mar 17 00:00:00 EDT 2022
Boosting the hypoxic response in myeloid cells accelerates resolution of fibrosis and regeneration of the liver in mice.
Oncotarget
Kantari-Mimoun C,Krzywinska E,Castells M,Milien C,Klose R,Meinecke AK,Lemberger U,Mathivet T,Gojkovic M,Schrödter K,Österreicher C,Fandrey J,Rundqvist H,Stockmann C
17-5932 was used in Flow cytometry/Cell sorting to show that the resolution of fibrosis can be accelerated by deleting VHL, a negative regulator of HIFs and VEGF, specifically in myeloid cells in mice.
Tue Feb 28 00:00:00 EST 2017
Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes.
Proceedings of the National Academy of Sciences of the United States of America
Hara T,Nakaoka HJ,Hayashi T,Mimura K,Hoshino D,Inoue M,Nagamura F,Murakami Y,Seiki M,Sakamoto T
17-5932-82 was used in Flow cytometry/Cell sorting to report that APBA3-deficient mice show reduced metastasis, with no apparent effect on primary tumor growth.
Tue May 30 00:00:00 EDT 2017
Analysis of the developmental stages, kinetics, and phenotypes exhibited by myeloid cells driven by GM-CSF in vitro.
PloS one
Rogers PB,Driessnack MG,Hiltbold Schwartz E
17-5932 was used in Flow cytometry/Cell sorting to study the developmental pathway of monocyte-derived, GM-CSF-driven dendritic cells.
Fri Sep 29 00:00:00 EDT 2017
Alternatively activated macrophages determine repair of the infarcted adult murine heart.
The Journal of clinical investigation
Shiraishi M,Shintani Y,Shintani Y,Ishida H,Saba R,Yamaguchi A,Adachi H,Yashiro K,Suzuki K
17-5932 was used in Flow cytometry/Cell sorting to study repair of the infarcted adult murine heart determined by alternatively activated macrophages.
Wed Jun 01 00:00:00 EDT 2016
Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.
Immunology
Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Sat Oct 01 00:00:00 EDT 2016
Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model.
Disease models & mechanisms
Chu CJ,Gardner PJ,Copland DA,Liyanage SE,Gonzalez-Cordero A,Kleine Holthaus SM,Luhmann UF,Smith AJ,Ali RR,Dick AD
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2016
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
Nature communications
Ruhland MK,Loza AJ,Capietto AH,Luo X,Knolhoff BL,Flanagan KC,Belt BA,Alspach E,Leahy K,Luo J,Schaffer A,Edwards JR,Longmore G,Faccio R,DeNardo DG,Stewart SA
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Wed Jun 08 00:00:00 EDT 2016
Ranitidine modifies myeloid cell populations and inhibits breast tumor development and spread in mice.
Oncoimmunology
Vila-Leahey A,Oldford SA,Marignani PA,Wang J,Haidl ID,Marshall JS
17-5932 was used in Flow cytometry/Cell sorting to study the effect of the histamine receptor 2 antagonist, Ranitidine, on immune cell function and tumour growth in breast cancer models.
Fri Jul 01 00:00:00 EDT 2016
The impact of ranitidine on monocyte responses in the context of solid tumors.
Oncotarget
Vila-Leahey A,Rogers D,Marshall JS
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Tue Mar 08 00:00:00 EST 2016
Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.
Scientific reports
Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Wed Jun 15 00:00:00 EDT 2016
Myeloid cell expressed proprotein convertase FURIN attenuates inflammation.
Oncotarget
Cordova ZM,Grönholm A,Kytölä V,Taverniti V,Hämäläinen S,Aittomäki S,Niininen W,Junttila I,Ylipää A,Nykter M,Pesu M
17593282 was used in flow cytometry to investigate the role of FURIN in LysM positive myeloid cells in vivo
Tue Aug 23 00:00:00 EDT 2016
Involvement of Receptor Activator of Nuclear Factor-κB Ligand (RANKL)-induced Incomplete Cytokinesis in the Polyploidization of Osteoclasts.
The Journal of biological chemistry
Takegahara N,Kim H,Mizuno H,Sakaue-Sawano A,Miyawaki A,Tomura M,Kanagawa O,Ishii M,Choi Y
17-5932 was used in Flow cytometry/Cell sorting to determine the mechanisms by which polyploidization of osteoclasts are controlled- an essential process for bone-resorbing activity.
Fri Feb 12 00:00:00 EST 2016
Taxanes enhance trastuzumab-mediated ADCC on tumor cells through NKG2D-mediated NK cell recognition.
Oncotarget
Di Modica M,Sfondrini L,Regondi V,Varchetta S,Oliviero B,Mariani G,Bianchi GV,Generali D,Balsari A,Triulzi T,Tagliabue E
17-5932 was used in Flow cytometry/Cell sorting to indicate that taxanes increase tumor susceptibility to ADCC by acting on tumor and NK cells.
Tue Jan 05 00:00:00 EST 2016
Apoptotic CD8 T-lymphocytes disable macrophage-mediated immunity to Trypanosoma cruzi infection.
Cell death & disease
Cabral-Piccin MP,Guillermo LV,Vellozo NS,Filardy AA,Pereira-Marques ST,Rigoni TS,Pereira-Manfro WF,DosReis GA,Lopes MF
17-5932 was used in Flow cytometry/Cell sorting to demonstrate that disposal of apoptotic CD8 T cells increases M2-macrophage differentiation and contributes to parasite persistence.
Thu May 19 00:00:00 EDT 2016
Novel whole blood assay for phenotyping platelet reactivity in mice identifies ICAM-1 as a mediator of platelet-monocyte interaction.
Blood
Armstrong PC,Kirkby NS,Chan MV,Finsterbusch M,Hogg N,Nourshargh S,Warner TD
17-5932 was used in Flow cytometry/Cell sorting to describe a novel method for testing platelet function using lower blood volumes, for use in the cardiovascular phenotyping of mice.
Thu Sep 03 00:00:00 EDT 2015
Cardiac-Restricted IGF-1Ea Overexpression Reduces the Early Accumulation of Inflammatory Myeloid Cells and Mediates Expression of Extracellular Matrix Remodelling Genes after Myocardial Infarction.
Mediators of inflammation
Gallego-Colon E,Sampson RD,Sattler S,Schneider MD,Rosenthal N,Tonkin J
17-5932 was used in Flow cytometry/Cell sorting to investigate the underlying molecular and cellular mechanisms behind the enhanced functional recovery following overexpression of IGF-1Ea.
Mon Aug 15 00:00:00 EDT 2016
Cysteine cathepsin activity suppresses osteoclastogenesis of myeloid-derived suppressor cells in breast cancer.
Oncotarget
Edgington-Mitchell LE,Rautela J,Duivenvoorden HM,Jayatilleke KM,van der Linden WA,Verdoes M,Bogyo M,Parker BS
17-5932 was used in Flow cytometry/Cell sorting to suggest that cysteine protease inhibition is associated with enhanced osteoclastogenesis of myeloid-derived suppressor cells in breast cancer.
Tue Sep 29 00:00:00 EDT 2015
Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.
PloS one
Szulzewsky F,Pelz A,Feng X,Synowitz M,Markovic D,Langmann T,Holtman IR,Wang X,Eggen BJ,Boddeke HW,Hambardzumyan D,Wolf SA,Kettenmann H
Published figure using Ly-6C monoclonal antibody (Product # 17-5932-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2016
Severity of DSS-induced colitis is reduced in Ido1-deficient mice with down-regulation of TLR-MyD88-NF-kB transcriptional networks.
Scientific reports
Shon WJ,Lee YK,Shin JH,Choi EY,Shin DM
17-5932 was used in Flow cytometry/Cell sorting to explore the role of IDO1 in producing inflammatory responses and modulating transcriptional networks during the development of colitis.
Fri Nov 27 00:00:00 EST 2015
BMP4 inhibits breast cancer metastasis by blocking myeloid-derived suppressor cell activity.
Cancer research
Cao Y,Slaney CY,Bidwell BN,Parker BS,Johnstone CN,Rautela J,Eckhardt BL,Anderson RL
17-5932 was used in Flow cytometry/Cell sorting to assess the potential for therapies based on the activation of BMP4 signalling for the treatment of breast cancer.
Mon Sep 15 00:00:00 EDT 2014
Intranasal vaccination promotes detrimental Th17-mediated immunity against influenza infection.
PLoS pathogens
Maroof A,Yorgensen YM,Li Y,Evans JT
17-5932 was used in Flow cytometry/Cell sorting to highlight the importance of both route of vaccination and adjuvant selection in vaccine development.
Wed Jan 01 00:00:00 EST 2014
Pneumolysin expression by streptococcus pneumoniae protects colonized mice from influenza virus-induced disease.
Virology
Wolf AI,Strauman MC,Mozdzanowska K,Williams KL,Osborne LC,Shen H,Liu Q,Garlick D,Artis D,Hensley SE,Caton AJ,Weiser JN,Erikson J
17-5932-82 was used in Flow Cytometry to investigate severity of influenza virus response with respiratory microbe presence.
Fri Aug 01 00:00:00 EDT 2014
Methotrexate treatment causes early onset of disease in a mouse model of Ross River virus-induced inflammatory disease through increased monocyte production.
PloS one
Taylor A,Sheng KC,Herrero LJ,Chen W,Rulli NE,Mahalingam S
17-5932 was used in Flow cytometry/Cell sorting to study infiltration of inflammatory cells to skeletal muscle in Ross River virus disease in response to MTX treatment.
Thu Mar 06 00:00:00 EST 2014
MT1-MMP regulates the PI3Kδ·Mi-2/NuRD-dependent control of macrophage immune function.
Genes & development
Shimizu-Hirota R,Xiong W,Baxter BT,Kunkel SL,Maillard I,Chen XW,Sabeh F,Liu R,Li XY,Weiss SJ
17-5932 was used in Flow cytometry/Cell sorting to investigate the role of macrophage-derived proteinases in immune regulation.
Wed Feb 15 00:00:00 EST 2012
Myeloid-derived suppressor cells from tumor-bearing mice impair TGF-β-induced differentiation of CD4+CD25+FoxP3+ Tregs from CD4+CD25-FoxP3- T cells.
Journal of leukocyte biology
Centuori SM,Trad M,LaCasse CJ,Alizadeh D,Larmonier CB,Hanke NT,Kartchner J,Janikashvili N,Bonnotte B,Larmonier N,Katsanis E
17-5932 was used in Flow cytometry/Cell sorting to indicate that gr-MDSCs from TB hosts have the unanticipated ability to restrict immunosuppressive Tregs.
Thu Nov 01 00:00:00 EDT 2012
Anti-Gr-1 antibody depletion fails to eliminate hepatic myeloid-derived suppressor cells in tumor-bearing mice.
Journal of leukocyte biology
Ma C,Kapanadze T,Gamrekelashvili J,Manns MP,Korangy F,Greten TF
17-5932 was used in Flow cytometry/Cell sorting to examine the effect of systemic RB6-8C5 treatment on hepatic myeloid-derived suppressor cells in tumour-bearing mice.
Sat Dec 01 00:00:00 EST 2012
MicroRNA-33 deficiency reduces the progression of atherosclerotic plaque in ApoE-/- mice.
Journal of the American Heart Association
Horie T,Baba O,Kuwabara Y,Chujo Y,Watanabe S,Kinoshita M,Horiguchi M,Nakamura T,Chonabayashi K,Hishizawa M,Hasegawa K,Kume N,Yokode M,Kita T,Kimura T,Ono K
17-5932 was used in Flow cytometry/Cell sorting to investigate the impact of the genetic loss of miR-33 in a mouse model of atherosclerosis.
Sat Dec 01 00:00:00 EST 2012
In vivo structure/function and expression analysis of the CX3C chemokine fractalkine.
Blood
Kim KW,Vallon-Eberhard A,Zigmond E,Farache J,Shezen E,Shakhar G,Ludwig A,Lira SA,Jung S
17-5932 was used in Flow cytometry/Cell sorting to study the CX3C chemokine interface in tissues of live animals.
Thu Nov 24 00:00:00 EST 2011
IL-1-induced inflammation promotes development of leishmaniasis in susceptible BALB/c mice.
International immunology
Voronov E,Dotan S,Gayvoronsky L,White RM,Cohen I,Krelin Y,Benchetrit F,Elkabets M,Huszar M,El-On J,Apte RN
17-5932 was used in Flow cytometry/Cell sorting to assess the role of host derived IL-1 on the course of Leishmania major infection in susceptible BLAB/c mice.
Thu Apr 01 00:00:00 EDT 2010
