Product References
TGFβ1+CCR5+ neutrophil subset increases in bone marrow and causes age-related osteoporosis in male mice.
Nature communications
Li J,Yao Z,Liu X,Duan R,Yi X,Ayoub A,Sanders JO,Mesfin A,Xing L,Boyce BF
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Wed Jan 11 00:00:00 EST 2023
Sympathetic Nerves Coordinate Corneal Epithelial Wound Healing by Controlling the Mobilization of Ly6Chi Monocytes From the Spleen to the Injured Cornea.
Investigative ophthalmology & visual science
He S,Liu J,Xue Y,Fu T,Li Z
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2023
Intranasal Delivery of Endothelial Cell-Derived Extracellular Vesicles with Supramolecular Gel Attenuates Myocardial Ischemia-Reperfusion Injury.
International journal of nanomedicine
Wang J,Tan Y,Dai Y,Hu K,Tan X,Jiang S,Li G,Zhang X,Kang L,Wang X,Xu B
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Thu Oct 05 00:00:00 EDT 2023
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J
53-5932-82 was used in Flow Cytometry to establish both direct and indirect roles for ILC2 in peri-aortic CaPO4 injury-induced mouse abdominal aortic aneurysms.
Wed Mar 01 00:00:00 EST 2023
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J
53-5932-82 was used in Flow Cytometry to establish both direct and indirect roles for ILC2 in peri-aortic CaPO4 injury-induced mouse abdominal aortic aneurysms.
Wed Mar 01 00:00:00 EST 2023
Macrophagic AMPKα1 orchestrates regenerative inflammation induced by glucocorticoids.
EMBO reports
Caratti G,Desgeorges T,Juban G,Stifel U,Fessard A,Koenen M,Caratti B,Théret M,Skurk C,Chazaud B,Tuckermann JP,Mounier R
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Mon Feb 06 00:00:00 EST 2023
Soluble TNF mediates amyloid-independent, diet-induced alterations to immune and neuronal functions in an Alzheimer's disease mouse model.
Frontiers in cellular neuroscience
MacPherson KP,Eidson LN,Houser MC,Weiss BE,Gollihue JL,Herrick MK,de Sousa Rodrigues ME,Sniffen L,Weekman EM,Hamilton AM,Kelly SD,Oliver DL,Yang Y,Chang J,Sampson TR,Norris CM,Tansey MG
53-5932-82 was used in Flow cytometry/Cell sorting to show that selective inhibition of soluble tumor necrosis factor signaling via the biologic XPro1595 modulates the effects of an high in fat and sugar (HFHS) diet in 5xFAD mice on peripheral and central immune profiles including CNS-associated CD8+ T cells, the composition of gut microbiota, and long-term potentiation deficits.
Sun May 12 00:00:00 EDT 2024
Group 2 innate lymphoid cells protect mouse heart from myocardial infarction injury via interleukin 5, eosinophils, and dendritic cells.
Cardiovascular research
Liu T,Meng Z,Liu J,Li J,Zhang Y,Deng Z,Luo S,Wang M,Huang Q,Zhang S,Fendt P,Devouassoux J,Li D,McKenzie ANJ,Nahrendorf M,Libby P,Guo J,Shi GP
53-5932-82 was used in Flow cytometry/Cell sorting to reveal an indirect cardiac reparative role of ILC2 in post-MI hearts via the IL5, EOS, and DC mechanism.
Tue May 02 00:00:00 EDT 2023
The NKCC1 ion transporter modulates microglial phenotype and inflammatory response to brain injury in a cell-autonomous manner.
PLoS biology
Tóth K,Lénárt N,Berki P,Fekete R,Szabadits E,Pósfai B,Cserép C,Alatshan A,Benkő S,Kiss D,Hübner CA,Gulyás A,Kaila K,Környei Z,Dénes Á
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2022
Gene-dosage effect of Pfkfb3 on monocyte/macrophage biology in atherosclerosis.
British journal of pharmacology
Guo S,Li A,Fu X,Li Z,Cao K,Song M,Huang S,Li Z,Yan J,Wang L,Dai X,Feng D,Wang Y,He J,Huo Y,Xu Y
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2022
Mineralocorticoid receptor antagonists and glucocorticoids differentially affect skeletal muscle inflammation and pathology in muscular dystrophy.
JCI insight
Howard ZM,Gomatam CK,Rabolli CP,Lowe J,Piepho AB,Bansal SS,Accornero F,Rafael-Fortney JA
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Mon Oct 10 00:00:00 EDT 2022
Therapeutic CFTR Correction Normalizes Systemic and Lung-Specific S1P Level Alterations Associated with Heart Failure.
International journal of molecular sciences
Uhl FE,Vanherle L,Matthes F,Meissner A
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Fri Jan 14 00:00:00 EST 2022
Helminth resistance is mediated by differential activation of recruited monocyte-derived alveolar macrophages and arginine depletion.
Cell reports
Chen F,El-Naccache DW,Ponessa JJ,Lemenze A,Espinosa V,Wu W,Lothstein K,Jin L,Antao O,Weinstein JS,Damani-Yokota P,Khanna K,Murray PJ,Rivera A,Siracusa MC,Gause WC
53-5932-82 was used in Flow Cytometry to indicate that recruited monocytes are selectively programmed in the pulmonary environment to express AM markers and an anti-helminth phenotype.
Tue Jan 11 00:00:00 EST 2022
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Pancreatic Cancer Chemotherapy Is Potentiated by Induction of Tertiary Lymphoid Structures in Mice.
Cellular and molecular gastroenterology and hepatology
Delvecchio FR,Fincham REA,Spear S,Clear A,Roy-Luzarraga M,Balkwill FR,Gribben JG,Bombardieri M,Hodivala-Dilke K,Capasso M,Kocher HM
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Mon Mar 28 00:00:00 EDT 2022
Disrupted Iron Metabolism and Mortality during Co-infection with Malaria and an Intestinal Gram-Negative Extracellular Pathogen.
Cell reports
Dos Santos LI,Torres TA,Diniz SQ,Gonçalves R,Caballero-Flores G,Núñez G,Gazzinelli RT,Maloy KJ,Ribeiro do V Antonelli L
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Myeloid DJ-1 deficiency protects acetaminophen-induced acute liver injury through decreasing inflammatory response.
Aging
Wang B,Li J,Jiao J,Xu M,Luo Y,Wang F,Xia Q,Gao Y,Feng Y,Kong X,Sun X
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Wed Jul 21 00:00:00 EDT 2021
NOX4 regulates macrophage apoptosis resistance to induce fibrotic progression.
The Journal of biological chemistry
Larson-Casey JL,Gu L,Kang J,Dhyani A,Carter AB
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Thu Jul 01 00:00:00 EDT 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
Abraxane-induced bone marrow CD11b+ myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with 64Cu-labeled anti-CD11b and prevented by anti-CSF-1.
Theranostics
Cao Q,Huang Q,Wang YA,Li C
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Fri Jul 23 00:00:00 EDT 2021
Inflammatory resolution and vascular barrier restoration after retinal ischemia reperfusion injury.
Journal of neuroinflammation
Abcouwer SF,Shanmugam S,Muthusamy A,Lin CM,Kong D,Hager H,Liu X,Antonetti DA
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Thu Aug 26 00:00:00 EDT 2021
Roles of lung-recruited monocytes and pulmonary Vascular Endothelial Growth Factor (VEGF) in resolving Ventilator-Induced Lung Injury (VILI).
PloS one
Lin CK,Huang TH,Yang CT,Shi CS
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Immunosuppression by Mutated Calreticulin Released from Malignant Cells.
Molecular cell
Liu P,Zhao L,Loos F,Marty C,Xie W,Martins I,Lachkar S,Qu B,Waeckel-Énée E,Plo I,Vainchenker W,Perez F,Rodriguez D,López-Otin C,van Endert P,Zitvogel L,Kepp O,Kroemer G
53-5932-82 was used in Flow Cytometry to demonstrate the paracrine immunosuppressive effects for exon-9-mutated C-terminally modified calreticulin.
Thu Feb 20 00:00:00 EST 2020
Plaque-associated myeloid cells derive from resident microglia in an Alzheimer's disease model.
The Journal of experimental medicine
Reed-Geaghan EG,Croxford AL,Becher B,Landreth GE
53-5932 was used in Flow cytometry/Cell sorting to genetically label different myeloid populations and unequivocally demonstrate that plaque-associated myeloid cells in the AD brain are derived exclusively from resident microglia.
Mon Apr 06 00:00:00 EDT 2020
Plaque-associated myeloid cells derive from resident microglia in an Alzheimer's disease model.
The Journal of experimental medicine
Reed-Geaghan EG,Croxford AL,Becher B,Landreth GE
53-5932 was used in Flow cytometry/Cell sorting to genetically label different myeloid populations and unequivocally demonstrate that plaque-associated myeloid cells in the AD brain are derived exclusively from resident microglia.
Mon Apr 06 00:00:00 EDT 2020
Proenkephalin+ regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function.
Proceedings of the National Academy of Sciences of the United States of America
Shime H,Odanaka M,Tsuiji M,Matoba T,Imai M,Yasumizu Y,Uraki R,Minohara K,Watanabe M,Bonito AJ,Fukuyama H,Ohkura N,Sakaguchi S,Morita A,Yamazaki S
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Tue Aug 25 00:00:00 EDT 2020
IgE Contributes to Atherosclerosis and Obesity by Affecting Macrophage Polarization, Macrophage Protein Network, and Foam Cell Formation.
Arteriosclerosis, thrombosis, and vascular biology
Zhang X,Li J,Luo S,Wang M,Huang Q,Deng Z,de Febbo C,Daoui A,Liew PX,Sukhova GK,Metso J,Jauhiainen M,Shi GP,Guo J
53-5932 was used in Flow cytometry/Cell sorting to demonstrate that IgE deficiency reduced atherosclerosis lesion burden, lesion lipid deposition, smooth muscle cell and endothelial cell contents, chemokine MCP (monocyte chemoattractant protein)-1 expression and macrophage accumulation.
Sun Mar 01 00:00:00 EST 2020
IgE Contributes to Atherosclerosis and Obesity by Affecting Macrophage Polarization, Macrophage Protein Network, and Foam Cell Formation.
Arteriosclerosis, thrombosis, and vascular biology
Zhang X,Li J,Luo S,Wang M,Huang Q,Deng Z,de Febbo C,Daoui A,Liew PX,Sukhova GK,Metso J,Jauhiainen M,Shi GP,Guo J
53-5932 was used in Flow cytometry/Cell sorting to demonstrate that IgE deficiency reduced atherosclerosis lesion burden, lesion lipid deposition, smooth muscle cell and endothelial cell contents, chemokine MCP (monocyte chemoattractant protein)-1 expression and macrophage accumulation.
Sun Mar 01 00:00:00 EST 2020
Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.
British journal of pharmacology
De Cicco P,Ercolano G,Rubino V,Terrazzano G,Ruggiero G,Cirino G,Ianaro A
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
Temporospatial distribution and transcriptional profile of retinal microglia in the oxygen-induced retinopathy mouse model.
Glia
Boeck M,Thien A,Wolf J,Hagemeyer N,Laich Y,Yusuf D,Backofen R,Zhang P,Boneva S,Stahl A,Hilgendorf I,Agostini H,Prinz M,Wieghofer P,Schlunck G,Schlecht A,Lange C
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2020
Characterization and regulation of osteoclast precursors following chronic Porphyromonas gingivalis infection.
Journal of leukocyte biology
Zhao Y,Li Z,Su L,Ballesteros-Tato A,Katz J,Michalek SM,Feng X,Zhang P
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Deficiency of immunoglobulin E protects mice from experimental abdominal aortic aneurysms.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Li J,Deng Z,Zhang X,Liu F,Yang C,Shi GP
53-5932 was used in Flow cytometry/Cell sorting to support a direct role of IgE in abdominal aortic aneurysm by promoting lesion chemokine expression, inflammatory cell accumulation, MAPK signalling and cytokine expression in mice.
Sat Feb 01 00:00:00 EST 2020
Antitumor Effect and Immune Response of Nanosecond Pulsed Electric Fields in Pancreatic Cancer.
Frontiers in oncology
Zhao J,Chen S,Zhu L,Zhang L,Liu J,Xu D,Tian G,Jiang T
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Fri Oct 28 00:00:00 EDT 2022
MOSPD2 is a therapeutic target for the treatment of CNS inflammation.
Clinical and experimental immunology
Yacov N,Kafri P,Salem Y,Propheta-Meiran O,Feldman B,Breitbart E,Mendel I
53-5932 was used in Flow cytometry/Cell sorting to study the therapeutic potential of MOSPD2 in central nervous system disease.
Sat Aug 01 00:00:00 EDT 2020
Effects of Hypertonic Saline and Hydroxyethyl Starch on Myeloid-Derived Suppressor Cells in Hemorrhagic Shock Mice under Secondary Bacterial Attack.
BioMed research international
Jiang JK,Hong LJ,Lu YQ
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
Site-1 protease ablation in the osterix-lineage in mice results in bone marrow neutrophilia and hematopoietic stem cell alterations.
Biology open
Patra D,Kim J,Zhang Q,Tycksen E,Sandell LJ
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Tue Jun 23 00:00:00 EDT 2020
The impact of Clonorchis sinensis infection on immune response in mice with type II collagen-induced arthritis.
BMC immunology
Li X,Yang Y,Qin S,Kong F,Yan C,Cheng W,Pan W,Yu Q,Hua H,Zheng K,Tang R
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Mon Feb 17 00:00:00 EST 2020
GDF3 Protects Mice against Sepsis-Induced Cardiac Dysfunction and Mortality by Suppression of Macrophage Pro-Inflammatory Phenotype.
Cells
Wang L,Li Y,Wang X,Wang P,Essandoh K,Cui S,Huang W,Mu X,Liu Z,Wang Y,Peng T,Fan GC
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Fri Jan 03 00:00:00 EST 2020
The Transcription Factor Nfix Requires RhoA-ROCK1 Dependent Phagocytosis to Mediate Macrophage Skewing during Skeletal Muscle Regeneration.
Cells
Saclier M,Lapi M,Bonfanti C,Rossi G,Antonini S,Messina G
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Fri Mar 13 00:00:00 EDT 2020
Extracellular miR-146a-5p Induces Cardiac Innate Immune Response and Cardiomyocyte Dysfunction.
ImmunoHorizons
Shimada BK,Yang Y,Zhu J,Wang S,Suen A,Kronstadt SM,Jeyaram A,Jay SM,Zou L,Chao W
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Mon Sep 21 00:00:00 EDT 2020
Resident macrophages acquire innate immune memory in staphylococcal skin infection.
eLife
Feuerstein R,Forde AJ,Lohrmann F,Kolter J,Ramirez NJ,Zimmermann J,Gomez de Agüero M,Henneke P
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Wed Jul 08 00:00:00 EDT 2020
Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway.
eLife
Kim EH,Woodruff MC,Grigoryan L,Maier B,Lee SH,Mandal P,Cortese M,Natrajan MS,Ravindran R,Ma H,Merad M,Gitlin AD,Mocarski ES,Jacob J,Pulendran B
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Tue Jun 09 00:00:00 EDT 2020
Gasdermin D in macrophages restrains colitis by controlling cGAS-mediated inflammation.
Science advances
Ma C,Yang D,Wang B,Wu C,Wu Y,Li S,Liu X,Lassen K,Dai L,Yang S
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Host Cathelicidin Exacerbates Group B Streptococcus Urinary Tract Infection.
mSphere
Patras KA,Coady A,Babu P,Shing SR,Ha AD,Rooholfada E,Brandt SL,Geriak M,Gallo RL,Nizet V
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Wed Apr 22 00:00:00 EDT 2020
A Stromal Niche Defined by Expression of the Transcription Factor WT1 Mediates Programming and Homeostasis of Cavity-Resident Macrophages.
Immunity
Buechler MB,Kim KW,Onufer EJ,Williams JW,Little CC,Dominguez CX,Li Q,Sandoval W,Cooper JE,Harris CA,Junttila MR,Randolph GJ,Turley SJ
53-5932 was used in Flow cytometry/Cell sorting to demonstrate that the GATA6 transcriptional program is a common feature of macrophages residing in all visceral body cavities.
Tue Jul 16 00:00:00 EDT 2019
A Regulatory Circuit Controlling the Dynamics of NFκB cRel Transitions B Cells from Proliferation to Plasma Cell Differentiation.
Immunity
Roy K,Mitchell S,Liu Y,Ohta S,Lin YS,Metzig MO,Nutt SL,Hoffmann A
53-5932-82 was used in Flow Cytometry to provide a mechanistic explanation of how dysregulation of this bi-stable circuit might result in pathologic B cell population phenotypes and thus offer new avenues for diagnostic stratification and treatment.
Tue Mar 19 00:00:00 EDT 2019
Increased flux through the mevalonate pathway mediates fibrotic repair without injury.
The Journal of clinical investigation
Larson-Casey JL,Vaid M,Gu L,He C,Cai GQ,Ding Q,Davis D,Berryhill TF,Wilson LS,Barnes S,Neighbors JD,Hohl RJ,Zimmerman KA,Yoder BK,Longhini ALF,Hanumanthu VS,Surolia R,Antony VB,Carter AB
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2019
The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis.
Cell reports
Hou X,Chen G,Bracamonte-Baran W,Choi HS,Diny NL,Sung J,Hughes D,Won T,Wood MK,Talor MV,Hackam DJ,Klingel K,Davogustto G,Taegtmeyer H,Coppens I,Barin JG,Čiháková D
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Tue Jul 02 00:00:00 EDT 2019
Regulatory T Cells Control the Switch From in situ to Invasive Breast Cancer.
Frontiers in immunology
Martinez LM,Robila V,Clark NM,Du W,Idowu MO,Rutkowski MR,Bos PD
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2020
IL-27 and TCR Stimulation Promote T Cell Expression of Multiple Inhibitory Receptors.
ImmunoHorizons
DeLong JH,O'Hara Hall A,Rausch M,Moodley D,Perry J,Park J,Phan AT,Beiting DP,Kedl RM,Hill JA,Hunter CA
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Tue Jan 15 00:00:00 EST 2019
Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner.
Cell
Thion MS,Low D,Silvin A,Chen J,Grisel P,Schulte-Schrepping J,Blecher R,Ulas T,Squarzoni P,Hoeffel G,Coulpier F,Siopi E,David FS,Scholz C,Shihui F,Lum J,Amoyo AA,Larbi A,Poidinger M,Buttgereit A,Lledo PM,Greter M,Chan JKY,Amit I,Beyer M,Schultze JL,Schlitzer A,Pettersson S,Ginhoux F,Garel S
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
Loss of NF-κB1 Causes Gastric Cancer with Aberrant Inflammation and Expression of Immune Checkpoint Regulators in a STAT-1-Dependent Manner.
Immunity
O'Reilly LA,Putoczki TL,Mielke LA,Low JT,Lin A,Preaudet A,Herold MJ,Yaprianto K,Tai L,Kueh A,Pacini G,Ferrero RL,Gugasyan R,Hu Y,Christie M,Wilcox S,Grumont R,Griffin MDW,O'Connor L,Smyth GK,Ernst M,Waring P,Gerondakis S,Strasser A
53-5932-82 was used in Flow Cytometry to provide mechanistic insight into how polymorphisms that attenuate NFKB1 expression predispose humans to epithelial cancers, highlighting the pro-tumorigenic activity of STAT1 and identifying targetable vulnerabilities in gastric cancer.
Tue Mar 20 00:00:00 EDT 2018
STAT3 Inhibition Combined with CpG Immunostimulation Activates Antitumor Immunity to Eradicate Genetically Distinct Castration-Resistant Prostate Cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research
Moreira D,Adamus T,Zhao X,Su YL,Zhang Z,White SV,Swiderski P,Lu X,DePinho RA,Pal SK,Kortylewski M
53-5932 was used in Flow cytometry/Cell sorting to show a novel strategy combining STAT3 inhibition with Toll-like Receptor 9 (TLR9) stimulation to unleash immune response against prostate cancers regardless of the genetic background.
Sat Dec 01 00:00:00 EST 2018
Nongenetic origins of cell-to-cell variability in B lymphocyte proliferation.
Proceedings of the National Academy of Sciences of the United States of America
Mitchell S,Roy K,Zangle TA,Hoffmann A
53-5932 was used in Flow cytometry/Cell sorting to characterise the role of molecular noise in determining phenotype heterogeneity.
Tue Mar 20 00:00:00 EDT 2018
Cytokine- and TCR-Mediated Regulation of T Cell Expression of Ly6C and Sca-1.
Journal of immunology (Baltimore, Md. : 1950)
DeLong JH,Hall AO,Konradt C,Coppock GM,Park J,Harms Pritchard G,Hunter CA
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2018
Advanced Glycation End Products Enhance Murine Monocyte Proliferation in Bone Marrow and Prime Them into an Inflammatory Phenotype through MAPK Signaling.
Journal of diabetes research
Jin X,Liu L,Zhang Y,Xiang Y,Yin G,Lu Y,Shi L,Dong J,Shen C
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Wed Oct 10 00:00:00 EDT 2018
iRhom2-mediated proinflammatory signalling regulates heart repair following myocardial infarction.
JCI insight
Barnette DN,Cahill TJ,Gunadasa-Rohling M,Carr CA,Freeman M,Riley PR
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Thu Feb 08 00:00:00 EST 2018
Differentiated macrophages acquire a pro-inflammatory and cell death-resistant phenotype due to increasing XIAP and p38-mediated inhibition of RipK1.
The Journal of biological chemistry
Rijal D,Ariana A,Wight A,Kim K,Alturki NA,Aamir Z,Ametepe ES,Korneluk RG,Tiedje C,Menon MB,Gaestel M,McComb S,Sad S
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Fri Jul 27 00:00:00 EDT 2018
The Combined Use of Melatonin and an Indoleamine 2,3-Dioxygenase-1 Inhibitor Enhances Vaccine-Induced Protective Cellular Immunity to HPV16-Associated Tumors.
Frontiers in immunology
Moreno ACR,Porchia BFMM,Pagni RL,Souza PDC,Pegoraro R,Rodrigues KB,Barros TB,Aps LRMM,de Araújo EF,Calich VLG,Ferreira LCS
53-5932 was used in Flow cytometry/Cell sorting to study the use of the combination of melatonin, a neuroimmunomodulator molecule, and an indoleamine 2,3-dioxygenase inhibitor to improve the efficacy of an immunotherapy targeting human papillomavirus.
Thu Sep 19 00:00:00 EDT 2019
Inhibition of Rspo-Lgr4 Facilitates Checkpoint Blockade Therapy by Switching Macrophage Polarization.
Cancer research
Tan B,Shi X,Zhang J,Qin J,Zhang N,Ren H,Qian M,Siwko S,Carmon K,Liu Q,Han H,Du B,Liu M
53-5932-82 was used in Flow cytometry/Cell sorting to identify Lgr4 as a critical switch in TAMs polarization and a potentially good drug target for cancer immune therapy.
Sat Sep 01 00:00:00 EDT 2018
Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity.
The Journal of experimental medicine
Thomas DC,Clare S,Sowerby JM,Pardo M,Juss JK,Goulding DA,van der Weyden L,Storisteanu D,Prakash A,Espéli M,Flint S,Lee JC,Hoenderdos K,Kane L,Harcourt K,Mukhopadhyay S,Umrania Y,Antrobus R,Nathan JA,Adams DJ,Bateman A,Choudhary JS,Lyons PA,Condliffe AM,Chilvers ER,Dougan G,Smith KG
53-5932 was used in Flow cytometry/Cell sorting to describe the key role of the previously uncharacterised protein Eros in host defence.
Mon Apr 03 00:00:00 EDT 2017
Mir-223 regulates the number and function of myeloid-derived suppressor cells in multiple sclerosis and experimental autoimmune encephalomyelitis.
Acta neuropathologica
Cantoni C,Cignarella F,Ghezzi L,Mikesell B,Bollman B,Berrien-Elliott MM,Ireland AR,Fehniger TA,Wu GF,Piccio L
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
CCR2- and CCR2+ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion.
Mucosal immunology
Liu J,Xue Y,Dong D,Xiao C,Lin C,Wang H,Song F,Fu T,Wang Z,Chen J,Pan H,Li Y,Cai D,Li Z
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2017
Infiltrating Myeloid Cells Exert Protumorigenic Actions via Neutrophil Elastase.
Molecular cancer research : MCR
Lerman I,Garcia-Hernandez ML,Rangel-Moreno J,Chiriboga L,Pan C,Nastiuk KL,Krolewski JJ,Sen A,Hammes SR
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2017
Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression.
Nature communications
Kalkavan H,Sharma P,Kasper S,Helfrich I,Pandyra AA,Gassa A,Virchow I,Flatz L,Brandenburg T,Namineni S,Heikenwalder M,Höchst B,Knolle PA,Wollmann G,von Laer D,Drexler I,Rathbun J,Cannon PM,Scheu S,Bauer J,Chauhan J,Häussinger D,Willimsky G,Löhning M,Schadendorf D,Brandau S,Schuler M,Lang PA,Lang KS
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Vaccine adjuvant MF59 promotes the intranodal differentiation of antigen-loaded and activated monocyte-derived dendritic cells.
PloS one
Cioncada R,Maddaluno M,Vo HTM,Woodruff M,Tavarini S,Sammicheli C,Tortoli M,Pezzicoli A,De Gregorio E,Carroll MC,D'Oro U,Piccioli D
53-5932 was used in Flow cytometry/Cell sorting to determine the role of MF59 in the recruitment and transportation of antigen presenting cells during an immune response.
Thu Nov 16 00:00:00 EST 2017
Alternatively activated macrophages determine repair of the infarcted adult murine heart.
The Journal of clinical investigation
Shiraishi M,Shintani Y,Shintani Y,Ishida H,Saba R,Yamaguchi A,Adachi H,Yashiro K,Suzuki K
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.
Immunology
Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Sat Oct 01 00:00:00 EDT 2016
Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model.
Disease models & mechanisms
Chu CJ,Gardner PJ,Copland DA,Liyanage SE,Gonzalez-Cordero A,Kleine Holthaus SM,Luhmann UF,Smith AJ,Ali RR,Dick AD
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2016
MIF Promotes Classical Activation and Conversion of Inflammatory Ly6C(high) Monocytes into TipDCs during Murine Toxoplasmosis.
Mediators of inflammation
Ruiz-Rosado Jde D,Olguín JE,Juárez-Avelar I,Saavedra R,Terrazas LI,Robledo-Avila FH,Vazquez-Mendoza A,Fernández J,Satoskar AR,Partida-Sánchez S,Rodriguez-Sosa M
53-5932 was used in Flow cytometry/Cell sorting to analyse the role of migration inhibitory factor in the maturation of CD11b(+) and CD8α (+) dendritic cells.
Fri Dec 30 00:00:00 EST 2016
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
Nature communications
Ruhland MK,Loza AJ,Capietto AH,Luo X,Knolhoff BL,Flanagan KC,Belt BA,Alspach E,Leahy K,Luo J,Schaffer A,Edwards JR,Longmore G,Faccio R,DeNardo DG,Stewart SA
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Wed Jun 08 00:00:00 EDT 2016
Ranitidine modifies myeloid cell populations and inhibits breast tumor development and spread in mice.
Oncoimmunology
Vila-Leahey A,Oldford SA,Marignani PA,Wang J,Haidl ID,Marshall JS
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Fri Jul 01 00:00:00 EDT 2016
The impact of ranitidine on monocyte responses in the context of solid tumors.
Oncotarget
Vila-Leahey A,Rogers D,Marshall JS
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Tue Mar 08 00:00:00 EST 2016
Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.
Scientific reports
Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Wed Jun 15 00:00:00 EDT 2016
Cysteine cathepsin activity suppresses osteoclastogenesis of myeloid-derived suppressor cells in breast cancer.
Oncotarget
Edgington-Mitchell LE,Rautela J,Duivenvoorden HM,Jayatilleke KM,van der Linden WA,Verdoes M,Bogyo M,Parker BS
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2015
Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.
PloS one
Szulzewsky F,Pelz A,Feng X,Synowitz M,Markovic D,Langmann T,Holtman IR,Wang X,Eggen BJ,Boddeke HW,Hambardzumyan D,Wolf SA,Kettenmann H
Published figure using Ly-6C monoclonal antibody (Product # 53-5932-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2016
