Product References
NLRP12-expressing dendritic cells mediate both dissemination of infection and adaptive immune responses in visceral leishmaniasis.
iScience
Valadares DG,Clay OS,Chen Y,Scorza BM,Cassel SL,Sutterwala FS,Wilson ME
47-5321-82 was used in Flow Cytometry to hypothesize that Nlrp12-expressing DCs are required for efficient dissemination and immune clearance of L. infantum from the site of initial infection.
Fri Mar 17 00:00:00 EDT 2023
QUAS-R: An SLC1A5-mediated glutamine uptake assay with single-cell resolution reveals metabolic heterogeneity with immune populations.
Cell reports
Pelgrom LR,Davis GM,O'Shaughnessy S,Wezenberg EJM,Van Kasteren SI,Finlay DK,Sinclair LV
47-5321-82 was used in Flow cytometry/Cell sorting to provide an easy sensitive single-cell assay to assess which cells support their function via SLC1A5-mediated uptake.
Tue Aug 29 00:00:00 EDT 2023
Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platform.
Genes & development
Naranjo S,Cabana CM,LaFave LM,Romero R,Shanahan SL,Bhutkar A,Westcott PMK,Schenkel JM,Ghosh A,Liao LZ,Del Priore I,Yang D,Jacks T
47-5321-82 was used in Immunohistochemistry to show that this organoid platform is a powerful, versatile new model system to study LUAD.
Mon Aug 01 00:00:00 EDT 2022
Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation.
Cell reports
Gros M,Segura E,Rookhuizen DC,Baudon B,Heurtebise-Chrétien S,Burgdorf N,Maurin M,Kapp EA,Simpson RJ,Kozik P,Villadangos JA,Bertrand MJM,Burbage M,Amigorena S
47-5321-82 was used in Flow cytometry/Cell sorting to demonstrate that membrane repair proves crucial in containing antigen export to the cytosol and cross-presentation in cDCs.
Tue Aug 16 00:00:00 EDT 2022
Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes.
Nature
Maschalidi S,Mehrotra P,Keçeli BN,De Cleene HKL,Lecomte K,Van der Cruyssen R,Janssen P,Pinney J,van Loo G,Elewaut D,Massie A,Hoste E,Ravichandran KS
47-5321-82 was used in Flow cytometry/Cell sorting to reveal that the membrane transporter SLC7A11 acts as a molecular brake on efferocytosis, the process by which dying cells are removed, and that inhibiting SLC7A11 function can accelerate wound healing.
Wed Jun 01 00:00:00 EDT 2022
Neutrophil-dendritic cell interaction plays an important role in live attenuated Leishmania vaccine induced immunity.
PLoS neglected tropical diseases
Bhattacharya P,Ismail N,Saxena A,Gannavaram S,Dey R,Oljuskin T,Akue A,Takeda K,Yu J,Karmakar S,Dagur PK,McCoy JP,Nakhasi HL
47-5321-82 was used in Flow Cytometry to show that LdCen-/- containing neutrophils phagocytized by DC markedly influence the phenotype and antigen presenting capacity of DCs early on and thus play an immune-regulatory role in shaping vaccine induced host protective response.
Tue Feb 01 00:00:00 EST 2022
Cancer cells dying from ferroptosis impede dendritic cell-mediated anti-tumor immunity.
Nature communications
Wiernicki B,Maschalidi S,Pinney J,Adjemian S,Vanden Berghe T,Ravichandran KS,Vandenabeele P
47-5321-82 was used in Flow cytometry/Cell sorting to show that ferroptosis negatively impacts antigen presenting cells and hence the adaptive immune response, which might hinder therapeutic applications of ferroptosis induction.
Mon Jun 27 00:00:00 EDT 2022
Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota.
Cell
Lima-Junior DS,Krishnamurthy SR,Bouladoux N,Collins N,Han SJ,Chen EY,Constantinides MG,Link VM,Lim AI,Enamorado M,Cataisson C,Gil L,Rao I,Farley TK,Koroleva G,Attig J,Yuspa SH,Fischbach MA,Kassiotis G,Belkaid Y
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Thu Jul 08 00:00:00 EDT 2021
CD11b Deficiency Exacerbates Methicillin-Resistant Staphylococcus aureus-Induced Sepsis by Upregulating Inflammatory Responses of Macrophages.
Immune network
Sim H,Jeong D,Kim HI,Pak S,Thapa B,Kwon HJ,Lee K
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Prostaglandin E2 serves a dual role in regulating the migration of dendritic cells.
International journal of molecular medicine
Diao G,Huang J,Zheng X,Sun X,Tian M,Han J,Guo J
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Wip1 regulates the immunomodulatory effects of murine mesenchymal stem cells in type 1 diabetes mellitus via targeting IFN-α/BST2.
Cell death discovery
Zhou N,Liu W,Zhang W,Liu Y,Li X,Wang Y,Zheng R,Zhang Y
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Fri Oct 29 00:00:00 EDT 2021
Topical arginase inhibition decreases growth of cutaneous squamous cell carcinoma.
Scientific reports
Mittal A,Wang M,Vidyarthi A,Yanez D,Pizzurro G,Thakral D,Tracy E,Colegio OR
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Mon May 24 00:00:00 EDT 2021
Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma.
Cell reports
Budhu S,Giese R,Gupta A,Fitzgerald K,Zappasodi R,Schad S,Hirschhorn D,Campesato LF,De Henau O,Gigoux M,Liu C,Mazo G,Deng L,Barker CA,Wolchok JD,Merghoub T
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway.
Journal of neuroinflammation
Duan RN,Yang CL,Du T,Liu A,Wang AR,Sun WJ,Li X,Li JX,Yan CZ,Liu QJ
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Mon Jun 28 00:00:00 EDT 2021
Frequent amplification of HDAC genes and efficacy of HDAC inhibitor chidamide and PD-1 blockade combination in soft tissue sarcoma.
Journal for immunotherapy of cancer
Que Y,Zhang XL,Liu ZX,Zhao JJ,Pan QZ,Wen XZ,Xiao W,Xu BS,Hong DC,Guo TH,Shen LJ,Fan WJ,Chen HY,Weng DS,Xu HR,Zhou PH,Zhang YZ,Niu XH,Zhang X
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Early activation of the cardiac CX3CL1/CX3CR1 axis delays β-adrenergic-induced heart failure.
Scientific reports
Flamant M,Mougenot N,Balse E,Le Fèvre L,Atassi F,Gautier EL,Le Goff W,Keck M,Nadaud S,Combadière C,Boissonnas A,Pavoine C
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Thu Sep 09 00:00:00 EDT 2021
Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40.
Nature communications
Yang F,He Z,Duan H,Zhang D,Li J,Yang H,Dorsey JF,Zou W,Nabavizadeh SA,Bagley SJ,Abdullah K,Brem S,Zhang L,Xu X,Byrne KT,Vonderheide RH,Gong Y,Fan Y
47-5321-82 was used in Flow Cytometry to investigate if an antibody cocktail-based immunotherapy that combines checkpoint blockade with dual-targeting of IL-6 and CD40 may offer exciting opportunities for glioblastoma and other solid tumors.
Tue Jun 08 00:00:00 EDT 2021
PP2Cδ Controls the Differentiation and Function of Dendritic Cells Through Regulating the NSD2/mTORC2/ACLY Pathway.
Frontiers in immunology
Lv N,Jin S,Liang Z,Wu X,Kang Y,Su L,Dong Y,Wang B,Ma T,Shi L
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Mon Feb 28 00:00:00 EST 2022
Inhibition of the Inflammasome Activity of NLRP3 Attenuates HDM-Induced Allergic Asthma.
Frontiers in immunology
Ma M,Li G,Qi M,Jiang W,Zhou R
47-5321-82 was used in Flow Cytometry to show that NLRP3 in myeloid cells promoted the development and progression of allergic asthma in an inflammasome-dependent manner.
Fri Dec 17 00:00:00 EST 2021
Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis.
Frontiers in immunology
Yang P,Tian H,Zou YR,Chambon P,Ichinose H,Honig G,Diamond B,Kim SJ
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Multi-color Flow Cytometry for Comprehensive Analysis of the Tumor Immune Infiltrate in a Murine Model of Breast Cancer.
Bio-protocol
Almeida AS,Fein MR,Egeblad M
47-5321-82 was used in Flow cytometry/Cell sorting to describe a detailed procedure for preparing a single-cell suspension from mammary tumors of the mouse mammary tumor virus-polyoma middle T (MMTV-PyMT) and analyzing these cells by multi-color flow cytometry.
Sat Jun 05 00:00:00 EDT 2021
Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver.
Immunity
Remmerie A,Martens L,Thoné T,Castoldi A,Seurinck R,Pavie B,Roels J,Vanneste B,De Prijck S,Vanhockerhout M,Binte Abdul Latib M,Devisscher L,Hoorens A,Bonnardel J,Vandamme N,Kremer A,Borghgraef P,Van Vlierberghe H,Lippens S,Pearce E,Saeys Y,Scott CL
47-5321 was used in Flow cytometry/Cell sorting to highlight considerable heterogeneity within the macrophage pool and suggest a need for more specific macrophage targeting strategies in metabolic-associated fatty liver disease (MAFLD).
Tue Sep 15 00:00:00 EDT 2020
Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis.
Immunity
Lou F,Sun Y,Xu Z,Niu L,Wang Z,Deng S,Liu Z,Zhou H,Bai J,Yin Q,Cai X,Sun L,Wang H,Li Q,Wu Z,Chen X,Gu J,Shi YL,Tao W,Ginhoux F,Wang H
47-5321-82 was used in Immunocytochemistry to suggest that urea cycle hyperreactivity and excessive polyamine generation in psoriatic keratinocytes promote self-RNA sensation and PP6 deregulation in keratinocytes is a pivotal event that amplifies the inflammatory circuits in psoriasis.
Tue Jul 14 00:00:00 EDT 2020
Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade.
Immunity
Bonavita E,Bromley CP,Jonsson G,Pelly VS,Sahoo S,Walwyn-Brown K,Mensurado S,Moeini A,Flanagan E,Bell CR,Chiang SC,Chikkanna-Gowda CP,Rogers N,Silva-Santos B,Jaillon S,Mantovani A,Reis e Sousa C,Guerra N,Davis DM,Zelenay S
47-5321-82 was used in Flow Cytometry to search for inflammatory regulators of cancer inhibition using patient datasets across human cancers.
Tue Dec 15 00:00:00 EST 2020
Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection.
Immunity
Bosteels C,Neyt K,Vanheerswynghels M,van Helden MJ,Sichien D,Debeuf N,De Prijck S,Bosteels V,Vandamme N,Martens L,Saeys Y,Louagie E,Lesage M,Williams DL,Tang SC,Mayer JU,Ronchese F,Scott CL,Hammad H,Guilliams M,Lambrecht BN
47-5321 was used in Flow cytometry/Cell sorting to show that monocyte-derived inflammatory DCs’’ are a mixture of monocyte-derived MCs that have little migratory and APC potential and bona fide pre-cDCderived, CD26-expressing inf-cDC2s that depend on Flt3L but not on GM-CSF.
Tue Jun 16 00:00:00 EDT 2020
BCG vaccination-induced emergency granulopoiesis provides rapid protection from neonatal sepsis.
Science translational medicine
Brook B,Harbeson DJ,Shannon CP,Cai B,He D,Ben-Othman R,Francis F,Huang J,Varankovich N,Liu A,Bao W,Bjerregaard-Andersen M,Schaltz-Buchholzer F,Sanca L,Golding CN,Larsen KL,Levy O,Kampmann B,Tan R,Charles A,Wynn JL,Shann F,Aaby P,Benn CS,Tebbutt SJ,Kollmann TR,Amenyogbe N
47-5321 was used in Flow cytometry/Cell sorting to show that BCG was also protective in a mouse model of neonatal polymicrobial sepsis, where it induced granulocyte colony-stimulating factor (G-CSF) within hours of administration.
Wed May 06 00:00:00 EDT 2020
Glufosinate constrains synchronous and metachronous metastasis by promoting anti-tumor macrophages.
EMBO molecular medicine
Menga A,Serra M,Todisco S,Riera-Domingo C,Ammarah U,Ehling M,Palmieri EM,Di Noia MA,Gissi R,Favia M,Pierri CL,Porporato PE,Castegna A,Mazzone M
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Wed Oct 07 00:00:00 EDT 2020
E6‑regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16‑positive cervical lesions.
International journal of oncology
Huang J,Diao G,Zhang Q,Chen Y,Han J,Guo J
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
IFN-β signalling regulates RAW 264.7 macrophage activation, cytokine production, and killing activity.
Innate immunity
Karimi Y,Giles EC,Vahedi F,Chew MV,Nham T,Loukov D,Lee AJ,Bowdish DM,Ashkar AA
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Dietary Glucose Consumption Promotes RALDH Activity in Small Intestinal CD103+CD11b+ Dendritic Cells.
Frontiers in immunology
Ko HJ,Hong SW,Verma R,Jung J,Lee M,Kim N,Kim D,Surh CD,Kim KS,Rudra D,Im SH
47-5321 was used in Flow cytometry/Cell sorting to reveal previously underappreciated role of dietary glucose concentration in establishing regulatory properties in intestinal DCs, thereby extending a potential therapeutic module against intestinal inflammation.
Mon Apr 19 00:00:00 EDT 2021
Dietary Glucose Consumption Promotes RALDH Activity in Small Intestinal CD103+CD11b+ Dendritic Cells.
Frontiers in immunology
Ko HJ,Hong SW,Verma R,Jung J,Lee M,Kim N,Kim D,Surh CD,Kim KS,Rudra D,Im SH
47-5321 was used in Flow cytometry/Cell sorting to reveal previously underappreciated role of dietary glucose concentration in establishing regulatory properties in intestinal DCs, thereby extending a potential therapeutic module against intestinal inflammation.
Mon Apr 19 00:00:00 EDT 2021
GDF3 Protects Mice against Sepsis-Induced Cardiac Dysfunction and Mortality by Suppression of Macrophage Pro-Inflammatory Phenotype.
Cells
Wang L,Li Y,Wang X,Wang P,Essandoh K,Cui S,Huang W,Mu X,Liu Z,Wang Y,Peng T,Fan GC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Fri Jan 03 00:00:00 EST 2020
Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells.
Nature communications
Lucas B,White AJ,Cosway EJ,Parnell SM,James KD,Jones ND,Ohigashi I,Takahama Y,Jenkinson WE,Anderson G
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Mon May 04 00:00:00 EDT 2020
Smooth muscle-derived progenitor cell myofibroblast differentiation through KLF4 downregulation promotes arterial remodeling and fibrosis.
JCI insight
Lu S,Jolly AJ,Strand KA,Dubner AM,Mutryn MF,Moulton KS,Nemenoff RA,Majesky MW,Weiser-Evans MC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Thu Dec 03 00:00:00 EST 2020
Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection.
Cell reports
Dokoshi T,Zhang LJ,Li F,Nakatsuji T,Butcher A,Yoshida H,Shimoda M,Okada Y,Gallo RL
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Tue Jan 07 00:00:00 EST 2020
Ly6cLo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation.
Scientific reports
Alkhani A,Levy CS,Tsui M,Rosenberg KA,Polovina K,Mattis AN,Mack M,Van Dyken S,Wang BM,Maher JJ,Nijagal A
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Tue Apr 28 00:00:00 EDT 2020
MiR-103 protects from recurrent spontaneous abortion via inhibiting STAT1 mediated M1 macrophage polarization.
International journal of biological sciences
Zhu X,Liu H,Zhang Z,Wei R,Zhou X,Wang Z,Zhao L,Guo Q,Zhang Y,Chu C,Wang L,Li X
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Fri Nov 12 00:00:00 EST 2021
Cancer cell-intrinsic expression of MHC II in lung cancer cell lines is actively restricted by MEK/ERK signaling and epigenetic mechanisms.
Journal for immunotherapy of cancer
Neuwelt AJ,Kimball AK,Johnson AM,Arnold BW,Bullock BL,Kaspar RE,Kleczko EK,Kwak JW,Wu MH,Heasley LE,Doebele RC,Li HY,Nemenoff RA,Clambey ET
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Immunomodulatory Effects of Recombinant Mycobacterium smegmatis Expressing Antigen-85B Epitopes in Infected J774A.1 Murine Macrophages.
Pathogens (Basel, Switzerland)
Kadir NA,Acosta A,Sarmiento ME,Norazmi MN
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Sun Nov 29 00:00:00 EST 2020
Artificial Mini Dendritic Cells Boost T Cell-Based Immunotherapy for Ovarian Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Cheng S,Xu C,Jin Y,Li Y,Zhong C,Ma J,Yang J,Zhang N,Li Y,Wang C,Yang Z,Wang Y
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Optimized Protocol for Isolation of Small Extracellular Vesicles from Human and Murine Lymphoid Tissues.
International journal of molecular sciences
Bordas M,Genard G,Ohl S,Nessling M,Richter K,Roider T,Dietrich S,Maaß KK,Seiffert M
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Tue Aug 04 00:00:00 EDT 2020
Skeletal muscle healing by M1-like macrophages produced by transient expression of exogenous GM-CSF.
Stem cell research & therapy
Martins L,Gallo CC,Honda TSB,Alves PT,Stilhano RS,Rosa DS,Koh TJ,Han SW
47-5321 was used in Flow cytometry/Cell sorting to study the show if increasing the number of M1-like macrophages immediately after traumatic muscle injury can promotes muscle recovery with less fibrosis, and if this can be achieved by the transient expression of GM-CSF.
Fri Nov 06 00:00:00 EST 2020
Skeletal muscle healing by M1-like macrophages produced by transient expression of exogenous GM-CSF.
Stem cell research & therapy
Martins L,Gallo CC,Honda TSB,Alves PT,Stilhano RS,Rosa DS,Koh TJ,Han SW
47-5321 was used in Flow cytometry/Cell sorting to study the show if increasing the number of M1-like macrophages immediately after traumatic muscle injury can promotes muscle recovery with less fibrosis, and if this can be achieved by the transient expression of GM-CSF.
Fri Nov 06 00:00:00 EST 2020
Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine.
Nature communications
Campesato LF,Budhu S,Tchaicha J,Weng CH,Gigoux M,Cohen IJ,Redmond D,Mangarin L,Pourpe S,Liu C,Zappasodi R,Zamarin D,Cavanaugh J,Castro AC,Manfredi MG,McGovern K,Merghoub T,Wolchok JD
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Tue Aug 11 00:00:00 EDT 2020
Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses.
Scientific reports
Hrdý J,Alard J,Couturier-Maillard A,Boulard O,Boutillier D,Delacre M,Lapadatescu C,Cesaro A,Blanc P,Pot B,Ryffel B,Chamaillard M,Grangette C
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Tue Mar 24 00:00:00 EDT 2020
Nuclear imaging-guided PD-L1 blockade therapy increases effectiveness of cancer immunotherapy.
Journal for immunotherapy of cancer
Gao H,Wu Y,Shi J,Zhang X,Liu T,Hu B,Jia B,Wan Y,Liu Z,Wang F
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Fri Jun 19 00:00:00 EDT 2020
Pharmacological depletion of microglia and perivascular macrophages prevents Vascular Cognitive Impairment in Ang II-induced hypertension.
Theranostics
Kerkhofs D,van Hagen BT,Milanova IV,Schell KJ,van Essen H,Wijnands E,Goossens P,Blankesteijn WM,Unger T,Prickaerts J,Biessen EA,van Oostenbrugge RJ,Foulquier S
47-5321 was used in Flow cytometry/Cell sorting to support the critical role of brain immune cells in the pathogenesis of hypertension-related cognitive impairment.
Tue Jun 01 00:00:00 EDT 2021
TLR9 Sensing of Self-DNA Controls Cell-Mediated Immunity to Listeria Infection via Rapid Conversion of Conventional CD4+ T Cells to Treg.
Cell reports
Dolina JS,Lee J,Griswold RQ,Labarta-Bajo L,Kannan S,Greenbaum JA,Bahia El Idrissi N,Pont MJ,Croft M,Schoenberger SP
47-5321 was used in Flow cytometry/Cell sorting to resolve long-standing questions regarding the conditional requirement for TH amongst pathogens and reveal a remarkable degree of plasticity in the function of CD4+ T cells, which can be quickly converted to Tregin vivo by infection-mediated immune modulation.
Tue Apr 07 00:00:00 EDT 2020
CDK4/6 inhibition promotes immune infiltration in ovarian cancer and synergizes with PD-1 blockade in a B cell-dependent manner.
Theranostics
Zhang QF,Li J,Jiang K,Wang R,Ge JL,Yang H,Liu SJ,Jia LT,Wang L,Chen BL
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Tue Jun 01 00:00:00 EDT 2021
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Mon Jun 29 00:00:00 EDT 2020
Polyanhydride Nanoparticles Induce Low Inflammatory Dendritic Cell Activation Resulting in CD8+ T Cell Memory and Delayed Tumor Progression.
International journal of nanomedicine
Darling R,Senapati S,Christiansen J,Liu L,Ramer-Tait AE,Narasimhan B,Wannemuehler M
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Mon Dec 07 00:00:00 EST 2020
The cis-Regulatory Atlas of the Mouse Immune System.
Cell
Yoshida H,Lareau CA,Ramirez RN,Rose SA,Maier B,Wroblewska A,Desland F,Chudnovskiy A,Mortha A,Dominguez C,Tellier J,Kim E,Dwyer D,Shinton S,Nabekura T,Qi Y,Yu B,Robinette M,Kim KW,Wagers A,Rhoads A,Nutt SL,Brown BD,Mostafavi S,Buenrostro JD,Benoist C
47-5321-82 was used in Flow Cytometry to generate matched epigenome and transcriptome measurements in 86 primary cell types that span the mouse immune system and its differentiation cascade.
Thu Feb 07 00:00:00 EST 2019
A Macrophage-Pericyte Axis Directs Tissue Restoration via Amphiregulin-Induced Transforming Growth Factor Beta Activation.
Immunity
Minutti CM,Modak RV,Macdonald F,Li F,Smyth DJ,Dorward DA,Blair N,Husovsky C,Muir A,Giampazolias E,Dobie R,Maizels RM,Kendall TJ,Griggs DW,Kopf M,Henderson NC,Zaiss DM
47-5321-82 was used in Flow Cytometry to identify macrophages as a critical source of Amphiregulin, revealing a direct effector mechanism by which these cells contribute to tissue restoration after acute injury.
Tue Mar 19 00:00:00 EDT 2019
cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity.
The Journal of clinical investigation
Wang Z,Chen J,Hu J,Zhang H,Xu F,He W,Wang X,Li M,Lu W,Zeng G,Zhou P,Huang P,Chen S,Li W,Xia LP,Xia X
47-5321 was used in Flow cytometry/Cell sorting to show that teniposide could trigger tumor immunogenicity and enable a potential chemoimmunotherapeutic approach to potentiating the therapeutic efficacy of anti-PD1 immunotherapy.
Tue Aug 13 00:00:00 EDT 2019
cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity.
The Journal of clinical investigation
Wang Z,Chen J,Hu J,Zhang H,Xu F,He W,Wang X,Li M,Lu W,Zeng G,Zhou P,Huang P,Chen S,Li W,Xia LP,Xia X
47-5321 was used in Flow cytometry/Cell sorting to show that teniposide could trigger tumor immunogenicity and enable a potential chemoimmunotherapeutic approach to potentiating the therapeutic efficacy of anti-PD1 immunotherapy.
Tue Aug 13 00:00:00 EDT 2019
Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection-Induced Neuropathic Pain.
Pain research & management
Sheng WS,Chauhan P,Hu S,Prasad S,Lokensgard JR
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Mon Dec 16 00:00:00 EST 2019
MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.
Journal for immunotherapy of cancer
Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Thu Nov 28 00:00:00 EST 2019
Multi-walled carbon nanotube oxidation dependent keratinocyte cytotoxicity and skin inflammation.
Particle and fibre toxicology
Palmer BC,Phelan-Dickenson SJ,DeLouise LA
47-5321 was used in Flow cytometry/Cell sorting to examine the role of carboxylation in multi-walled carbon nanotube skin toxicity.
Tue Jan 08 00:00:00 EST 2019
Transcriptional Signature Derived from Murine Tumor-Associated Macrophages Correlates with Poor Outcome in Breast Cancer Patients.
Cell reports
Tuit S,Salvagno C,Kapellos TS,Hau CS,Seep L,Oestreich M,Klee K,de Visser KE,Ulas T,Schultze JL
47-5321 was used in Flow cytometry/Cell sorting to show that a transgenic mouse tumor model can yield a TAM signature relevant for human breast cancer outcome prognosis and provide a generalizable strategy for determining and applying immune cell signatures provided the murine model reflects the human disease.
Tue Oct 29 00:00:00 EDT 2019
Mast Cells Are Mediators of Fibrosis and Effector Cell Recruitment in Dermal Chronic Graft-vs.-Host Disease.
Frontiers in immunology
Strattan E,Palaniyandi S,Kumari R,Du J,Hakim N,Huang T,Kesler MV,Jennings CD,Sturgill JL,Hildebrandt GC
47-5321-82 was used in Flow cytometry/Cell sorting to show for the first time a role for mast cells in skin chronic graft-vs-host disease that may be targetable for preventive and therapeutic intervention in this disease.
Tue Nov 17 00:00:00 EST 2020
LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy.
Nature communications
Pascual-García M,Bonfill-Teixidor E,Planas-Rigol E,Rubio-Perez C,Iurlaro R,Arias A,Cuartas I,Sala-Hojman A,Escudero L,Martínez-Ricarte F,Huber-Ruano I,Nuciforo P,Pedrosa L,Marques C,Braña I,Garralda E,Vieito M,Squatrito M,Pineda E,Graus F,Espejo C,Sahuquillo J,Tabernero J,Seoane J
47-5321-82 was used in Flow Cytometry to study the effect of the combination of LIF neutralising antibodies with the inhibition of the PD1 immune checkpoint on tumour progression.
Tue Jun 11 00:00:00 EDT 2019
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
Macrophage-specific MHCII expression is regulated by a remote Ciita enhancer controlled by NFAT5.
The Journal of experimental medicine
Buxadé M,Huerga Encabo H,Riera-Borrull M,Quintana-Gallardo L,López-Cotarelo P,Tellechea M,Martínez-Martínez S,Redondo JM,Martín-Caballero J,Flores JM,Bosch E,Rodríguez-Fernández JL,Aramburu J,López-Rodríguez C
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Mon Nov 05 00:00:00 EST 2018
Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation.
The Journal of experimental medicine
Carpier JM,Zucchetti AE,Bataille L,Dogniaux S,Shafaq-Zadah M,Bardin S,Lucchino M,Maurin M,Joannas LD,Magalhaes JG,Johannes L,Galli T,Goud B,Hivroz C
47-5321 was used in Flow cytometry/Cell sorting to study the retrograde traffic of linker for activation of T cells from the plasma membrane to the Golgi-trans-Golgi network.
Mon Apr 02 00:00:00 EDT 2018
MicroRNA-150 controls differentiation of intraepithelial lymphocytes through TGF-β receptor II regulation.
The Journal of allergy and clinical immunology
Seo SH,Jang MS,Kim DJ,Kim SM,Oh SC,Jung CR,Park Y,Ha SJ,Jung H,Park YJ,Yoon SR,Choi I,Kim TD
47-5321 was used in Flow cytometry/Cell sorting to investigate the regulation of intraepithelial lymphocyte differentiation and the underlying mechanisms in mice.
Sun Apr 01 00:00:00 EDT 2018
FACS isolation of live mouse eosinophils at high purity via a protocol that does not target Siglec F.
Journal of immunological methods
Geslewitz WE,Percopo CM,Rosenberg HF
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2018
Myeloid apolipoprotein E controls dendritic cell antigen presentation and T cell activation.
Nature communications
Bonacina F,Coe D,Wang G,Longhi MP,Baragetti A,Moregola A,Garlaschelli K,Uboldi P,Pellegatta F,Grigore L,Da Dalt L,Annoni A,Gregori S,Xiao Q,Caruso D,Mitro N,Catapano AL,Marelli-Berg FM,Norata GD
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Mon Aug 06 00:00:00 EDT 2018
CD4+ T cells are activated in regional lymph nodes and migrate to skin to initiate lymphedema.
Nature communications
García Nores GD,Ly CL,Cuzzone DA,Kataru RP,Hespe GE,Torrisi JS,Huang JJ,Gardenier JC,Savetsky IL,Nitti MD,Yu JZ,Rehal S,Mehrara BJ
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Thu May 17 00:00:00 EDT 2018
Lin-CCR2+ hematopoietic stem and progenitor cells overcome resistance to PD-1 blockade.
Nature communications
Flores CT,Wildes TJ,Drake JA,Moore GL,Dean BD,Abraham RS,Mitchell DA
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Wed Oct 17 00:00:00 EDT 2018
The autophagy receptor SQSTM1/p62 mediates anti-inflammatory actions of the selective NR3C1/glucocorticoid receptor modulator compound A (CpdA) in macrophages.
Autophagy
Mylka V,Deckers J,Ratman D,De Cauwer L,Thommis J,De Rycke R,Impens F,Libert C,Tavernier J,Vanden Berghe W,Gevaert K,De Bosscher K
47-5321-82 was used in Flow cytometry/Cell sorting to demonstrate how off-target mechanisms of selective NR3C1 ligands may contribute to a more efficient anti-inflammatory therapy.
Tue Oct 22 00:00:00 EDT 2019
Epidermal Growth Factor Receptor Expression Licenses Type-2 Helper T Cells to Function in a T Cell Receptor-Independent Fashion.
Immunity
Minutti CM,Drube S,Blair N,Schwartz C,McCrae JC,McKenzie AN,Kamradt T,Mokry M,Coffer PJ,Sibilia M,Sijts AJ,Fallon PG,Maizels RM,Zaiss DM
47-5321 was used in Flow cytometry/Cell sorting to reveal a mechanism by which antigen presentation controls the innate effector function of Th2 cells at the site of inflammation.
Tue Oct 17 00:00:00 EDT 2017
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
The Journal of clinical investigation
Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control.
The Journal of experimental medicine
Schwartz C,Khan AR,Floudas A,Saunders SP,Hams E,Rodewald HR,McKenzie ANJ,Fallon PG
47-5321 was used in Flow cytometry/Cell sorting to study how group 2 innate lymphoid cells regulate adaptive Th2 cell functions.
Mon Sep 04 00:00:00 EDT 2017
Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells.
Frontiers in immunology
Bai WJ,Li CG,Zhang CC,Xu LH,Zeng QZ,Hu B,Hong Z,He XH,Ouyang DY
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice.
Neurobiology of disease
MacPherson KP,Sompol P,Kannarkat GT,Chang J,Sniffen L,Wildner ME,Norris CM,Tansey MG
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
Cross-Presentation of Soluble and Cell-Associated Antigen by Murine Hepatocytes Is Enhanced by Collectrin Expression.
Journal of immunology (Baltimore, Md. : 1950)
Dolina JS,Cechova S,Rudy CK,Sung SJ,Tang WW,Lee J,Hahn YS,Le TH
47-5321 was used in Flow cytometry/Cell sorting to identify the functional role of collectrin in the liver.
Wed Mar 15 00:00:00 EDT 2017
Discrimination of the heterogeneity of bone marrow‑derived dendritic cells.
Molecular medicine reports
Wang J,Dai X,Hsu C,Ming C,He Y,Zhang J,Wei L,Zhou P,Wang CY,Yang J,Gong N
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Wed Nov 01 00:00:00 EDT 2017
Loss of IRF2BP2 in Microglia Increases Inflammation and Functional Deficits after Focal Ischemic Brain Injury.
Frontiers in cellular neuroscience
Cruz SA,Hari A,Qin Z,Couture P,Huang H,Lagace DC,Stewart AFR,Chen HH
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Thu Mar 17 00:00:00 EDT 2022
Role of a novel immune modulating DDR2-expressing population in silica-induced pulmonary fibrosis.
PloS one
McDonald LT,Johnson SD,Russell DL,Young MRI,LaRue AC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Mon Sep 25 00:00:00 EDT 2017
Location of tumor affects local and distant immune cell type and number.
Immunity, inflammation and disease
Hensel JA,Khattar V,Ashton R,Lee C,Siegal GP,Ponnazhagan S
47-5321 was used in Flow cytometry/Cell sorting to demonstrate that location of tumour, and not simply the tumour itself, has a definitive role in regulating immune effectors.
Wed Mar 01 00:00:00 EST 2017
Microvasculature remodeling in the mouse lower gut during inflammaging.
Scientific reports
Jeong JH,Kim K,Lim D,Kim KH,Kim HS,Lee S,Song JH,Moon BG,Choy HE,Park SC
47-5321 was used in Flow cytometry/Cell sorting to show that microvessels in aging mouse intestine were progressively deprived of supportive structures, microvessel-associated pericytes and adherens junction protein vascular endothelial (VE)-cadherin, and became leaky.
Tue Jan 03 00:00:00 EST 2017
Smac mimetics and oncolytic viruses synergize in driving anticancer T-cell responses through complementary mechanisms.
Nature communications
Kim DS,Dastidar H,Zhang C,Zemp FJ,Lau K,Ernst M,Rakic A,Sikdar S,Rajwani J,Naumenko V,Balce DR,Ewanchuk BW,Tailor P,Yates RM,Jenne C,Gafuik C,Mahoney DJ
47-5321 was used in Flow cytometry/Cell sorting to show that SMC and OV therapies combination also synergize in vivo by promoting anticancer immunity through an increase in CD8(+) T-cell response.
Thu Aug 24 00:00:00 EDT 2017
Microglial brain region-dependent diversity and selective regional sensitivities to aging.
Nature neuroscience
Grabert K,Michoel T,Karavolos MH,Clohisey S,Baillie JK,Stevens MP,Freeman TC,Summers KM,McColl BW
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth.
Stem cells translational medicine
Zheng H,Zou W,Shen J,Xu L,Wang S,Fu YX,Fan W
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Recruited monocytes modulate malaria-induced lung injury through CD36-mediated clearance of sequestered infected erythrocytes.
Journal of leukocyte biology
Lagassé HA,Anidi IU,Craig JM,Limjunyawong N,Poupore AK,Mitzner W,Scott AL
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Mon Aug 15 00:00:00 EDT 2016
Effects of ketanserin on experimental colitis in mice and macrophage function.
International journal of molecular medicine
Xiao J,Shao L,Shen J,Jiang W,Feng Y,Zheng P,Liu F
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Repulsive guidance molecule a blockade exerts the immunoregulatory function in DCs stimulated with ABP and LPS.
Human vaccines & immunotherapeutics
Xu X,Gao Y,Zhai Z,Zhang S,Shan F,Feng J
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Tue Aug 02 00:00:00 EDT 2016
Thiol peroxiredoxin, a novel allergen from Bombyx mori, modulates functions of macrophages and dendritic cells.
American journal of translational research
Wang H,Hu W,Liang Z,Zeng L,Li J,Yan H,Yang P,Liu Z,Wang L
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Stroke sensitivity in the aged: sex chromosome complement vs. gonadal hormones.
Aging
McCullough LD,Mirza MA,Xu Y,Bentivegna K,Steffens EB,Ritzel R,Liu F
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Fri Jul 01 00:00:00 EDT 2016
Epidermal RAF prevents allergic skin disease.
eLife
Raguz J,Jeric I,Niault T,Nowacka JD,Kuzet SE,Rupp C,Fischer I,Biggi S,Borsello T,Baccarini M
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Tue Jul 19 00:00:00 EDT 2016
Internalization and presentation of myelin antigens by the brain endothelium guides antigen-specific T cell migration.
eLife
Lopes Pinheiro MA,Kamermans A,Garcia-Vallejo JJ,van Het Hof B,Wierts L,O'Toole T,Boeve D,Verstege M,van der Pol SM,van Kooyk Y,de Vries HE,Unger WW
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Thu Jun 23 00:00:00 EDT 2016
High Fat Diet Inhibits Dendritic Cell and T Cell Response to Allergens but Does Not Impair Inhalational Respiratory Tolerance.
PloS one
Pizzolla A,Oh DY,Luong S,Prickett SR,Henstridge DC,Febbraio MA,O'Hehir RE,Rolland JM,Hardy CL
47-5321 was used in Flow cytometry/Cell sorting to study the relationship between a high fat diet and allergic asthma using an induced-respiratory tolerance model in mice.
Wed Jul 26 00:00:00 EDT 2017
Adaptive Immune Regulation of Mammary Postnatal Organogenesis.
Developmental cell
Plaks V,Boldajipour B,Linnemann JR,Nguyen NH,Kersten K,Wolf Y,Casbon AJ,Kong N,van den Bijgaart RJ,Sheppard D,Melton AC,Krummel MF,Werb Z
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Mon Sep 14 00:00:00 EDT 2015
The late endosomal adaptor molecule p14 (LAMTOR2) regulates TGFβ1-mediated homeostasis of Langerhans cells.
The Journal of investigative dermatology
Sparber F,Tripp CH,Komenda K,Scheffler JM,Clausen BE,Huber LA,Romani N,Stoitzner P
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
Altered lymph node composition in diphtheria toxin receptor-based mouse models to ablate dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
van Blijswijk J,Schraml BU,Rogers NC,Whitney PG,Zelenay S,Acton SE,Reis e Sousa C
47-5321 was used in Flow cytometry/Cell sorting to report that mice in which DTR is expressed on DCs display lymph node hypocellularity and reduced frequency of DCs in the same organs.
Thu Jan 01 00:00:00 EST 2015
Yersinia pestis targets neutrophils via complement receptor 3.
Cellular microbiology
Merritt PM,Nero T,Bohman L,Felek S,Krukonis ES,Marketon MM
47-5321 was used in Flow cytometry/Cell sorting to identify the factors involved in the targeting of murine splenocytes by Yersinia pestis.
Fri May 01 00:00:00 EDT 2015
Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway.
Molecular medicine reports
Huang L,Kong Y,Wang J,Sun J,Shi Q,Qiu YH
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Macrophages Contribute to the Spermatogonial Niche in the Adult Testis.
Cell reports
DeFalco T,Potter SJ,Williams AV,Waller B,Kan MJ,Capel B
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Tue Aug 18 00:00:00 EDT 2015
High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity.
Nature
Schulz MD,Atay C,Heringer J,Romrig FK,Schwitalla S,Aydin B,Ziegler PK,Varga J,Reindl W,Pommerenke C,Salinas-Riester G,Böck A,Alpert C,Blaut M,Polson SC,Brandl L,Kirchner T,Greten FR,Polson SW,Arkan MC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Thu Oct 23 00:00:00 EDT 2014
Immunoglobulin E plays an immunoregulatory role in lupus.
The Journal of experimental medicine
Dema B,Charles N,Pellefigues C,Ricks TK,Suzuki R,Jiang C,Scheffel J,Hasni S,Hoffman V,Jablonski M,Sacré K,Gobert D,Papo T,Daugas E,Crampton S,Bolland S,Rivera J
47-5321 was used in Flow cytometry/Cell sorting to explore the effect of IgE deficiency on the inflammatory response in FcγRIIB-deficient mice, which hastens and results in a more aggressive lupuslike disease.
Mon Oct 20 00:00:00 EDT 2014
Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge.
Human vaccines & immunotherapeutics
Wang S,Wu B,Xue J,Wang M,Chen R,Wang B
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Mon Jan 05 00:00:00 EST 2015
BCG vaccine mediated reduction in the MHC-II expression of macrophages and dendritic cells is reversed by activation of Toll-like receptors 7 and 9.
Cellular immunology
Bakhru P,Sirisaengtaksin N,Soudani E,Mukherjee S,Khan A,Jagannath C
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2014
Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.
PloS one
Xiao GY,Liu IH,Cheng CC,Chang CC,Lee YH,Cheng WT,Wu SC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Thu May 28 00:00:00 EDT 2015
Assessing the role of STAT3 in DC differentiation and autologous DC immunotherapy in mouse models of GBM.
PloS one
Assi H,Espinosa J,Suprise S,Sofroniew M,Doherty R,Zamler D,Lowenstein PR,Castro MG
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Fri Jan 23 00:00:00 EST 2015
Altered leukotriene B4 metabolism in CYP4F18-deficient mice does not impact inflammation following renal ischemia.
Biochimica et biophysica acta
Winslow V,Vaivoda R,Vasilyev A,Dombkowski D,Douaidy K,Stark C,Drake J,Guilliams E,Choudhary D,Preffer F,Stoilov I,Christmas P
47-5321 was used in Flow cytometry/Cell sorting to conclude that CYP4F18 is necessary for omega oxidation of leukotriene B4 in neutrophils, and is not compensated by other CYP enzymes.
Sun Jun 01 00:00:00 EDT 2014
Differential uptake of nanoparticles and microparticles by pulmonary APC subsets induces discrete immunological imprints.
Journal of immunology (Baltimore, Md. : 1950)
Hardy CL,Lemasurier JS,Mohamud R,Yao J,Xiang SD,Rolland JM,O'Hehir RE,Plebanski M
47-5321 was used in Flow cytometry/Cell sorting to study the uptake of different sized particles by lung macrophages and dendritic cells.
Fri Nov 15 00:00:00 EST 2013
Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages.
Blood
He H,Xu J,Warren CM,Duan D,Li X,Wu L,Iruela-Arispe ML
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Thu Oct 11 00:00:00 EDT 2012
Eosinophil contamination of thioglycollate-elicited peritoneal macrophage cultures skews the functional readouts of in vitro assays.
Journal of leukocyte biology
Misharin AV,Saber R,Perlman H
47-5321 was used in Flow cytometry/Cell sorting to examine the presence of other cell types in freshly isolated and cultured thioglycollate-elicited peritoneal cells.
Wed Aug 01 00:00:00 EDT 2012
Isolation and characterization of novel murine epiphysis derived mesenchymal stem cells.
PloS one
Cheng CC,Lian WS,Hsiao FS,Liu IH,Lin SP,Lee YH,Chang CC,Xiao GY,Huang HY,Cheng CF,Cheng WT,Wu SC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Fri Sep 07 00:00:00 EDT 2012
Mycobacterium bovis BCG decreases MHC-II expression in vivo on murine lung macrophages and dendritic cells during aerosol infection.
Cellular immunology
Pecora ND,Fulton SA,Reba SM,Drage MG,Simmons DP,Urankar-Nagy NJ,Boom WH,Harding CV
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 47-5321-82) in Flow Cytometry
Fri Jan 02 00:00:00 EST 2009