Product References
Platelet factors attenuate inflammation and rescue cognition in ageing.
Nature
Schroer AB,Ventura PB,Sucharov J,Misra R,Chui MKK,Bieri G,Horowitz AM,Smith LK,Encabo K,Tenggara I,Couthouis J,Gross JD,Chan JM,Luke A,Villeda SA
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2023
Deletion of CD36 exhibits limited impact on normal hematopoiesis and the leukemia microenvironment.
Cellular & molecular biology letters
Meng Y,Pospiech M,Ali A,Chandwani R,Vergel M,Onyemaechi S,Yaghmour G,Lu R,Alachkar H
48-0452-82 was used in Flow cytometry/Cell sorting to investigate whether targeting CD36 has any detrimental impact on normal hematopoietic cells.
Wed May 24 00:00:00 EDT 2023
Conserved stromal-immune cell circuits secure B cell homeostasis and function.
Nature immunology
Lütge M,De Martin A,Gil-Cruz C,Perez-Shibayama C,Stanossek Y,Onder L,Cheng HW,Kurz L,Cadosch N,Soneson C,Robinson MD,Stoeckli SJ,Ludewig B,Pikor NB
48-0452-82 was used in Flow cytometry/Cell sorting to reveal that a canonical set of immune cell-provided cues enforce bidirectional signaling programs that sustain functional BRC niches across lymphoid organs and species, thereby securing efficient humoral immunity.
Sat Jul 01 00:00:00 EDT 2023
Transient expansion and myofibroblast conversion of adipogenic lineage precursors mediate bone marrow repair after radiation.
JCI insight
Zhong L,Yao L,Holdreith N,Yu W,Gui T,Miao Z,Elkaim Y,Li M,Gong Y,Pacifici M,Maity A,Busch TM,Joeng KS,Cengel K,Seale P,Tong W,Qin L
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Fri Apr 08 00:00:00 EDT 2022
Lenvatinib for effectively treating antiangiogenic drug-resistant nasopharyngeal carcinoma.
Cell death & disease
Sun Q,Wang Y,Ji H,Sun X,Xie S,Chen L,Li S,Zeng W,Chen R,Tang Q,Zuo J,Hou L,Hosaka K,Lu Y,Liu Y,Ye Y,Yang Y
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Fri Aug 19 00:00:00 EDT 2022
Redox regulation of age-associated defects in generation and maintenance of T cell self-tolerance and immunity to foreign antigens.
Cell reports
Hester AK,Semwal MK,Cepeda S,Xiao Y,Rueda M,Wimberly K,Venables T,Dileepan T,Kraig E,Griffith AV
48-0452-82 was used in Flow Cytometry to find that diminished expression of a model tissue-restricted antigen gene in aged thymic stromal cells correlates with impaired clonal deletion of cognate T cells recognizing an autoantigen involved in atherosclerosis.
Tue Feb 15 00:00:00 EST 2022
Tet-mediated DNA demethylation regulates specification of hematopoietic stem and progenitor cells during mammalian embryogenesis.
Science advances
Ma L,Tang Q,Gao X,Lee J,Lei R,Suzuki M,Zheng D,Ito K,Frenette PS,Dawlaty MM
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Fri Mar 04 00:00:00 EST 2022
Sphk2 deletion is involved in structural abnormalities and Th17 response but does not aggravate colon inflammation induced by sub-chronic stress.
Scientific reports
Martín-Hernández D,Gutiérrez IL,González-Prieto M,MacDowell KS,Robledo-Montaña J,Tendilla-Beltrán H,Calleja-Rodríguez N,Bris ÁG,Ulecia-Morón C,Moreno B,Caso JR,García-Bueno B,Rodrigues-Mascarenhas S,Marín-Jiménez I,Leza JC,Menchén L
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Tue Mar 08 00:00:00 EST 2022
Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration.
Nature communications
Lin C,Yang Q,Guo D,Xie J,Yang YS,Chaugule S,DeSouza N,Oh WT,Li R,Chen Z,John AA,Qiu Q,Zhu LJ,Greenblatt MB,Ghosh S,Li S,Gao G,Haynes C,Emerson CP,Shim JH
48-0452-82 was used in Flow cytometry/Cell sorting to identify mitochondrial oxidative phosphorylation as the prominent energy-driving force for osteogenesis of skeletal progenitors, governing musculoskeletal integrity.
Fri Nov 11 00:00:00 EST 2022
A new murine model of Barth syndrome neutropenia links TAFAZZIN deficiency to increased ER stress-induced apoptosis.
Blood advances
Sohn J,Milosevic J,Brouse T,Aziz N,Elkhoury J,Wang S,Hauschild A,van Gastel N,Cetinbas M,Tufa SF,Keene DR,Sadreyev RI,Pu WT,Sykes DB
48-0452-82 was used in Flow cytometry/Cell sorting to examine myeloid progenitor development within the fetal liver of TAFAZZIN knockout (KO) animals as well as within the adult bone marrow of wild-type recipients transplanted with TAFAZZIN-KO hematopoietic stem cells.
Tue Apr 26 00:00:00 EDT 2022
cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory.
Science immunology
Christian DA,Adams TA,Shallberg LA,Phan AT,Smith TE,Abraha M,Perry J,Ruthel G,Clark JT,Pritchard GH,Aronson LR,Gossa S,McGavern DB,Kedl RM,Hunter CA
48-0452-82 was used in Flow Cytometry to investigate how conventional type 1 dendritic cells (cDC1s) in the peritoneal cavity's omentum coordinate innate responses to microbial challenge and provide secondary signals required for CD8+ T cell expansion and memory formation, particularly after intraperitoneal immunization with Toxoplasma gondii.
Fri Sep 30 00:00:00 EDT 2022
The disordered N-terminal domain of DNMT3A recognizes H2AK119ub and is required for postnatal development.
Nature genetics
Gu T,Hao D,Woo J,Huang TW,Guo L,Lin X,Guzman AG,Tovy A,Rosas C,Jeong M,Zhou Y,Deneen B,Huang Y,Li W,Goodell MA
48-0452-82 was used in Flow Cytometry to demonstrate an isoform-specific role for DNMT3A1 in mouse postnatal development and reveal the N terminus as a necessary regulatory domain for DNMT3A1 chromatin occupancy and functions in the nervous system.
Sun May 01 00:00:00 EDT 2022
Differential Engraftment of Parental A20 PD-L1 WT and PD-L1 KO Leukemia Cells in Semiallogeneic Recipients in the Context of PD-L1/PD-1 Interaction and NK Cell-Mediated Hybrid Resistance.
Frontiers in immunology
Del Rio ML,Perez-Simon JA,Rodriguez-Barbosa JI
48-0452-82 was used in Flow cytometry/Cell sorting to show that PD-L1 expression on A20 leukemia tumor cells modulates CD8 T-cell-mediated responses to tumor-specific antigens but does not contribute to inhibit NK cell-mediated hybrid resistance, which correlates with the inability to detect PD-1 expression on NK cells neither under steady-state conditions nor under inflammatory conditions.
Fri Jul 08 00:00:00 EDT 2022
YTHDF2 suppresses the plasmablast genetic program and promotes germinal center formation.
Cell reports
Grenov A,Hezroni H,Lasman L,Hanna JH,Shulman Z
48-0452-82 was used in Flow Cytometry to reveal how post-transcriptional suppression of gene expression directs appropriate B cell fate commitment during initiation of the adaptive immune response.
Tue May 03 00:00:00 EDT 2022
MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism.
Cancer cell
Ueda K,Kumari R,Schwenger E,Wheat JC,Bohorquez O,Narayanagari SR,Taylor SJ,Carvajal LA,Pradhan K,Bartholdy B,Todorova TI,Goto H,Sun D,Chen J,Shan J,Song Y,Montagna C,Xiong S,Lozano G,Pellagatti A,Boultwood J,Verma A,Steidl U
48-0452-82 was used in Flow cytometry/Cell sorting to identify MDMX overexpression as a pervasive preleukemic-to-AML transition mechanism in different genetically driven disease subtypes, and reveal Wnt/β-Catenin as a non-canonical MDMX-driven pathway with therapeutic potential for progression prevention and cancer interception.
Mon Apr 12 00:00:00 EDT 2021
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
The Journal of experimental medicine
Ho TT,Dellorusso PV,Verovskaya EV,Bakker ST,Flach J,Smith LK,Ventura PB,Lansinger OM,Hérault A,Zhang SY,Kang YA,Mitchell CA,Villeda SA,Passegué E
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Monocyte-derived dendritic cells link localized secretory IgA deficiency to adaptive immune activation in COPD.
Mucosal immunology
Richmond BW,Mansouri S,Serezani A,Novitskiy S,Blackburn JB,Du RH,Fuseini H,Gutor S,Han W,Schaff J,Vasiukov G,Xin MK,Newcomb DC,Jin L,Blackwell TS,Polosukhin VV
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Mon Mar 01 00:00:00 EST 2021
A rapid CRISPR competitive assay for in vitro and in vivo discovery of potential drug targets affecting the hematopoietic system.
Computational and structural biotechnology journal
Shen Y,Jiang L,Iyer VS,Raposo B,Dubnovitsky A,Boddul SV,Kasza Z,Wermeling F
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Wed Nov 10 00:00:00 EST 2021
Murine myeloid cell MCPIP1 suppresses autoimmunity by regulating B-cell expansion and differentiation.
Disease models & mechanisms
Dobosz E,Lorenz G,Ribeiro A,Würf V,Wadowska M,Kotlinowski J,Schmaderer C,Potempa J,Fu M,Koziel J,Lech M
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Thu Mar 18 00:00:00 EDT 2021
Defining the Mechanistic Correlates of Protection Conferred by Whole-Cell Vaccination against Pseudomonas aeruginosa Acute Murine Pneumonia.
Infection and immunity
Sen-Kilic E,Blackwood CB,Huckaby AB,Horspool AM,Weaver KL,Malkowski AC,Witt WT,Bevere JR,Damron FH,Barbier M
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Tue Jan 19 00:00:00 EST 2021
Polyvinyl alcohol hydrolysis rate and molecular weight influence human and murine HSC activity ex vivo.
Stem cell research
Sudo K,Yamazaki S,Wilkinson AC,Nakauchi H,Nakamura Y
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2021
Role of CXCL5 in Regulating Chemotaxis of Innate and Adaptive Leukocytes in Infected Lungs Upon Pulmonary Influenza Infection.
Frontiers in immunology
Guo L,Li N,Yang Z,Li H,Zheng H,Yang J,Chen Y,Zhao X,Mei J,Shi H,Worthen GS,Liu L
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Tue Feb 08 00:00:00 EST 2022
Hypoxia-induced miR-210 modulates the inflammatory response and fibrosis upon acute ischemia.
Cell death & disease
Zaccagnini G,Greco S,Longo M,Maimone B,Voellenkle C,Fuschi P,Carrara M,Creo P,Maselli D,Tirone M,Mazzone M,Gaetano C,Spinetti G,Martelli F
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Sat May 01 00:00:00 EDT 2021
Ibrutinib does not prevent kidney fibrosis following acute and chronic injury.
Scientific reports
Belliere J,Casemayou A,Colliou E,El Hachem H,Kounde C,Piedrafita A,Feuillet G,Schanstra JP,Faguer S
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Mon Jun 07 00:00:00 EDT 2021
High-throughput analysis of lung immune cells in a combined murine model of agriculture dust-triggered airway inflammation with rheumatoid arthritis.
PloS one
Gaurav R,Mikuls TR,Thiele GM,Nelson AJ,Niu M,Guda C,Eudy JD,Barry AE,Wyatt TA,Romberger DJ,Duryee MJ,England BR,Poole JA
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Thu Jul 08 00:00:00 EDT 2021
Proteostasis in dendritic cells is controlled by the PERK signaling axis independently of ATF4.
Life science alliance
Mendes A,Gigan JP,Rodriguez Rodrigues C,Choteau SA,Sanseau D,Barros D,Almeida C,Camosseto V,Chasson L,Paton AW,Paton JC,Argüello RJ,Lennon-Duménil AM,Gatti E,Pierre P
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Mon Feb 01 00:00:00 EST 2021
Impaired HA-specific T follicular helper cell and antibody responses to influenza vaccination are linked to inflammation in humans.
eLife
Hill DL,Whyte CE,Innocentin S,Lee JL,Dooley J,Wang J,James EA,Lee JC,Kwok WW,Zand MS,Liston A,Carr EJ,Linterman MA
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Tue Nov 02 00:00:00 EDT 2021
Metabolic preconditioning in CD4+ T cells restores inducible immune tolerance in lupus-prone mice.
JCI insight
Wilson CS,Stocks BT,Hoopes EM,Rhoads JP,McNew KL,Major AS,Moore DJ
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Fri Oct 08 00:00:00 EDT 2021
The folate cycle enzyme MTHFD2 induces cancer immune evasion through PD-L1 up-regulation.
Nature communications
Shang M,Yang H,Yang R,Chen T,Fu Y,Li Y,Fang X,Zhang K,Zhang J,Li H,Cao X,Gu J,Xiao J,Zhang Q,Liu X,Yu Q,Wang T
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Mon Mar 29 00:00:00 EDT 2021
The folate cycle enzyme MTHFD2 induces cancer immune evasion through PD-L1 up-regulation.
Nature communications
Shang M,Yang H,Yang R,Chen T,Fu Y,Li Y,Fang X,Zhang K,Zhang J,Li H,Cao X,Gu J,Xiao J,Zhang Q,Liu X,Yu Q,Wang T
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Mon Mar 29 00:00:00 EDT 2021
Type 2 diabetic mice enter a state of spontaneous hibernation-like suspended animation following accumulation of uric acid.
The Journal of biological chemistry
Zhao Y,Cheng R,Zhao Y,Ge W,Yang Y,Ding Z,Xu X,Wang Z,Wu Z,Zhang J
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2021
Targeting Ovarian Carcinoma with TSP-1:CD47 Antagonist TAX2 Activates Anti-Tumor Immunity.
Cancers
Jeanne A,Sarazin T,Charlé M,Moali C,Fichel C,Boulagnon-Rombi C,Callewaert M,Andry MC,Diesis E,Delolme F,Rioult D,Dedieu S
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Thu Oct 07 00:00:00 EDT 2021
Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation.
eLife
Wilfahrt D,Philips RL,Lama J,Kizerwetter M,Shapiro MJ,McCue SA,Kennedy MM,Rajcula MJ,Zeng H,Shapiro VS
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Protein Assays and Analysis
Thu Dec 02 00:00:00 EST 2021
Mechanism of a COVID-19 nanoparticle vaccine candidate that elicits a broadly neutralizing antibody response to SARS-CoV-2 variants.
Science advances
Zhang YN,Paynter J,Sou C,Fourfouris T,Wang Y,Abraham C,Ngo T,Zhang Y,He L,Zhu J
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry (Frozen)
Fri Oct 22 00:00:00 EDT 2021
tiRNA signaling via stress-regulated vesicle transfer in the hematopoietic niche.
Cell stem cell
Kfoury YS,Ji F,Mazzola M,Sykes DB,Scherer AK,Anselmo A,Akiyama Y,Mercier F,Severe N,Kokkaliaris KD,Zhao T,Brouse T,Saez B,Seidl J,Papazian A,Ivanov P,Mansour MK,Sadreyev RI,Scadden DT
48-0452-82 was used in Flow cytometry/Cell sorting to show that extracellular vesicle-mediated tiRNA transfer provides a stress-modulated signalling axis, distinct from conventional stress responses, in the bone marow niche.
Thu Dec 02 00:00:00 EST 2021
Depletion of Retinal Dopaminergic Activity in a Mouse Model of Rod Dysfunction Exacerbates Experimental Autoimmune Uveoretinitis: A Role for the Gateway Reflex.
International journal of molecular sciences
Stofkova A,Zloh M,Andreanska D,Fiserova I,Kubovciak J,Hejda J,Kutilek P,Murakami M
48-0452-82 was used in Flow cytometry/Cell sorting to hypothesize that rod photoreceptor dysfunction causes remodeling of retinal neural activity, which influences the blood-retinal barrier and the development of retinal inflammation.
Fri Dec 31 00:00:00 EST 2021
The impact of stress on the transcriptomic signature of iNKT1 cells.
Biochemistry and biophysics reports
Papadogianni G,Ravens I,Hassan A,Dittrich-Breiholz O,Bernhardt G,Georgiev H
48-0452-82 was used in Flow Cytometry to conclude that to avoid erroneous conclusions, a comparison of expression profiles must take into consideration the history of cell preparation.
Wed Dec 01 00:00:00 EST 2021
Mitochondrial ubiquinol oxidation is necessary for tumour growth.
Nature
Martínez-Reyes I,Cardona LR,Kong H,Vasan K,McElroy GS,Werner M,Kihshen H,Reczek CR,Weinberg SE,Gao P,Steinert EM,Piseaux R,Budinger GRS,Chandel NS
48-0452 was used in Flow cytometry/Cell sorting to indicate that tumour growth requires the ETC to oxidize ubiquinol, which is essential to drive the oxidative TCA cycle and DHODH activity.
Tue Sep 01 00:00:00 EDT 2020
SARS-CoV-2 mRNA Vaccines Foster Potent Antigen-Specific Germinal Center Responses Associated with Neutralizing Antibody Generation.
Immunity
Lederer K,Castaño D,Gómez Atria D,Oguin TH,Wang S,Manzoni TB,Muramatsu H,Hogan MJ,Amanat F,Cherubin P,Lundgreen KA,Tam YK,Fan SHY,Eisenlohr LC,Maillard I,Weissman D,Bates P,Krammer F,Sempowski GD,Pardi N,Locci M
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Tue Dec 15 00:00:00 EST 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
Synergistic factors control kinase-phosphatase organization in B-cells engaged with supported bilayers.
Molecular biology of the cell
Núñez MF,Wisser K,Veatch SL
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunocytochemistry
Thu Mar 19 00:00:00 EDT 2020
Pituitary Adenylate Cyclase-Activating Polypeptide Alleviates Intestinal, Extra-Intestinal and Systemic Inflammatory Responses during Acute Campylobacter jejuni-induced Enterocolitis in Mice.
Pathogens (Basel, Switzerland)
Heimesaat MM,Mousavi S,Kløve S,Genger C,Weschka D,Tamas A,Reglodi D,Bereswill S
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry (Paraffin)
Wed Sep 30 00:00:00 EDT 2020
Pituitary Adenylate Cyclase-Activating Polypeptide Alleviates Intestinal, Extra-Intestinal and Systemic Inflammatory Responses during Acute Campylobacter jejuni-induced Enterocolitis in Mice.
Pathogens (Basel, Switzerland)
Heimesaat MM,Mousavi S,Kløve S,Genger C,Weschka D,Tamas A,Reglodi D,Bereswill S
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry (Paraffin)
Wed Sep 30 00:00:00 EDT 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
Toll-Like Receptor-4 Dependent Intestinal and Systemic Sequelae Following Peroral Campylobacter coli Infection of IL10 Deficient Mice Harboring a Human Gut Microbiota.
Pathogens (Basel, Switzerland)
Kløve S,Genger C,Mousavi S,Weschka D,Bereswill S,Heimesaat MM
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Mon May 18 00:00:00 EDT 2020
Ischemia Reperfusion Injury Triggers CXCL13 Release and B-Cell Recruitment After Allogenic Kidney Transplantation.
Frontiers in immunology
Kreimann K,Jang MS,Rong S,Greite R,von Vietinghoff S,Schmitt R,Bräsen JH,Schiffer L,Gerstenberg J,Vijayan V,Dittrich-Breiholz O,Wang L,Karsten CM,Gwinner W,Haller H,Immenschuh S,Gueler F
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Mon Apr 12 00:00:00 EDT 2021
Overcoming Immunological Challenges to Helper-Dependent Adenoviral Vector-Mediated Long-Term CFTR Expression in Mouse Airways.
Genes
Cao H,Duan R,Hu J
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Mon May 18 00:00:00 EDT 2020
Myeloid Cell CK2 Regulates Inflammation and Resistance to Bacterial Infection.
Frontiers in immunology
Larson SR,Bortell N,Illies A,Crisler WJ,Matsuda JL,Lenz LL
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Tue Jul 27 00:00:00 EDT 2021
Shp1 Loss Enhances Macrophage Effector Function and Promotes Anti-Tumor Immunity.
Frontiers in immunology
Myers DR,Abram CL,Wildes D,Belwafa A,Welsh AMN,Schulze CJ,Choy TJ,Nguyen T,Omaque N,Hu Y,Singh M,Hansen R,Goldsmith MA,Quintana E,Smith JAM,Lowell CA
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Mon Jun 14 00:00:00 EDT 2021
Fucoxanthin Ameliorates Atopic Dermatitis Symptoms by Regulating Keratinocytes and Regulatory Innate Lymphoid Cells.
International journal of molecular sciences
Natsume C,Aoki N,Aoyama T,Senda K,Matsui M,Ikegami A,Tanaka K,Azuma YT,Fujita T
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Sun Mar 22 00:00:00 EDT 2020
The Host-Specific Intestinal Microbiota Composition Impacts Campylobacter coli Infection in a Clinical Mouse Model of Campylobacteriosis.
Pathogens (Basel, Switzerland)
Heimesaat MM,Genger C,Klove S,Weschka D,Mousavi S,Bereswill S
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Tue Sep 29 00:00:00 EDT 2020
B Cell Diversification Is Uncoupled from SAP-Mediated Selection Forces in Chronic Germinal Centers within Peyer's Patches.
Cell reports
Biram A,Winter E,Denton AE,Zaretsky I,Dassa B,Bemark M,Linterman MA,Yaari G,Shulman Z
48-0452-82 was used in Flow cytometry/Cell sorting to demonstrate that T cell-derived help to B cells in PPs includes SAP-dependent and SAP-independent functions.
Tue Feb 11 00:00:00 EST 2020
Cep55 overexpression promotes genomic instability and tumorigenesis in mice.
Communications biology
Sinha D,Nag P,Nanayakkara D,Duijf PHG,Burgess A,Raninga P,Smits VAJ,Bain AL,Subramanian G,Wall M,Finnie JW,Kalimutho M,Khanna KK
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Wed Oct 21 00:00:00 EDT 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Fri Jun 19 00:00:00 EDT 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Fri Jun 19 00:00:00 EDT 2020
Aging-Affected MSC Functions and Severity of Periodontal Tissue Destruction in a Ligature-Induced Mouse Periodontitis Model.
International journal of molecular sciences
Aung KT,Akiyama K,Kunitomo M,Mun AY,Tosa I,Nguyen HTT,Zhang J,Kohno T,Ono M,Hara ES,Kuboki T
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunocytochemistry
Fri Oct 30 00:00:00 EDT 2020
Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state.
Nature communications
Kawabe T,Yi J,Kawajiri A,Hilligan K,Fang D,Ishii N,Yamane H,Zhu J,Jankovic D,Kim KS,Trinchieri G,Sher A
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Mon Jul 06 00:00:00 EDT 2020
Human and Mouse Transcriptome Profiling Identifies Cross-Species Homology in Pulmonary and Lymph Node Mononuclear Phagocytes.
Cell reports
Leach SM,Gibbings SL,Tewari AD,Atif SM,Vestal B,Danhorn T,Janssen WJ,Wager TD,Jakubzick CV
48-0452 was used in Flow cytometry/Cell sorting to created a gene expression compendium across 24 distinct human and murine lung and lymph node mononuclear phagocyte (MP), along with human blood and murine spleen MPs, to serve as validation datasets.
Tue Nov 03 00:00:00 EST 2020
Compartmentalized gut lymph node drainage dictates adaptive immune responses.
Nature
Esterházy D,Canesso MCC,Mesin L,Muller PA,de Castro TBR,Lockhart A,ElJalby M,Faria AMC,Mucida D
48-0452 was used in Flow cytometry/Cell sorting to show drainage of gut-draining lymph nodes can resolve conflicting tolerogenic and inflammatory intestinal responses by encouraging antigen targeting to specific gut segments.
Wed May 01 00:00:00 EDT 2019
Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10.
Cell
Rojas OL,Pröbstel AK,Porfilio EA,Wang AA,Charabati M,Sun T,Lee DSW,Galicia G,Ramaglia V,Ward LA,Leung LYT,Najafi G,Khaleghi K,Garcillán B,Li A,Besla R,Naouar I,Cao EY,Chiaranunt P,Burrows K,Robinson HG,Allanach JR,Yam J,Luck H,Campbell DJ,Allman D,Brooks DG,Tomura M,Baumann R,Zamvil SS,Bar-Or A,Horwitz MS,Winer DA,Mortha A,Mackay F,Prat A,Osborne LC,Robbins C,Baranzini SE,Gommerman JL
48-0452-82 was used in Flow Cytometry to show that IgA+ plasmablast and/or plasma cells mobilized from the gut play an role in suppressing neuroinflammation.
Thu Jan 24 00:00:00 EST 2019
The cis-Regulatory Atlas of the Mouse Immune System.
Cell
Yoshida H,Lareau CA,Ramirez RN,Rose SA,Maier B,Wroblewska A,Desland F,Chudnovskiy A,Mortha A,Dominguez C,Tellier J,Kim E,Dwyer D,Shinton S,Nabekura T,Qi Y,Yu B,Robinette M,Kim KW,Wagers A,Rhoads A,Nutt SL,Brown BD,Mostafavi S,Buenrostro JD,Benoist C
48-0452-82 was used in Flow Cytometry to generate matched epigenome and transcriptome measurements in 86 primary cell types that span the mouse immune system and its differentiation cascade.
Thu Feb 07 00:00:00 EST 2019
Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis.
Immunity
Castro-Dopico T,Dennison TW,Ferdinand JR,Mathews RJ,Fleming A,Clift D,Stewart BJ,Jing C,Strongili K,Labzin LI,Monk EJM,Saeb-Parsy K,Bryant CE,Clare S,Parkes M,Clatworthy MR
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunofluorescence
Tue Apr 16 00:00:00 EDT 2019
Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis.
Immunity
Castro-Dopico T,Dennison TW,Ferdinand JR,Mathews RJ,Fleming A,Clift D,Stewart BJ,Jing C,Strongili K,Labzin LI,Monk EJM,Saeb-Parsy K,Bryant CE,Clare S,Parkes M,Clatworthy MR
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunofluorescence
Tue Apr 16 00:00:00 EDT 2019
A Regulatory Circuit Controlling the Dynamics of NFκB cRel Transitions B Cells from Proliferation to Plasma Cell Differentiation.
Immunity
Roy K,Mitchell S,Liu Y,Ohta S,Lin YS,Metzig MO,Nutt SL,Hoffmann A
48-0452-82 was used in Flow Cytometry to provide a mechanistic explanation of how dysregulation of this bi-stable circuit might result in pathologic B cell population phenotypes and thus offer new avenues for diagnostic stratification and treatment.
Tue Mar 19 00:00:00 EDT 2019
Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis.
Cell metabolism
Camell CD,Günther P,Lee A,Goldberg EL,Spadaro O,Youm YH,Bartke A,Hubbard GB,Ikeno Y,Ruddle NH,Schultze J,Dixit VD
48-0452 was used in Flow cytometry/Cell sorting to study the role of ageing within alterations of adipose tissue.
Tue Dec 03 00:00:00 EST 2019
The chemokine receptor CCR7 is a promising target for rheumatoid arthritis therapy.
Cellular & molecular immunology
Moschovakis GL,Bubke A,Friedrichsen M,Ristenpart J,Back JW,Falk CS,Kremmer E,Förster R
48-0452-82 was used in Flow Cytometry to demonstrate that CCR7 signaling is essential for the induction of CIA and identify CCR7 as a potential therapeutic target in RA.
Tue Oct 01 00:00:00 EDT 2019
Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells.
Frontiers in immunology
Xu J,Pei S,Wang Y,Liu J,Qian Y,Huang M,Zhang Y,Xiao Y
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Wed Oct 14 00:00:00 EDT 2020
Bacteroides fragilis polysaccharide A induces IL-10 secreting B and T cells that prevent viral encephalitis.
Nature communications
Ramakrishna C,Kujawski M,Chu H,Li L,Mazmanian SK,Cantin EM
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Tue May 14 00:00:00 EDT 2019
The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells.
Cell reports
Adane B,Ye H,Khan N,Pei S,Minhajuddin M,Stevens BM,Jones CL,D'Alessandro A,Reisz JA,Zaberezhnyy V,Gasparetto M,Ho TC,Kelly KK,Myers JR,Ashton JM,Siegenthaler J,Kume T,Campbell EL,Pollyea DA,Becker MW,Jordan CT
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Tue Apr 02 00:00:00 EDT 2019
In Situ Modification of Tissue Stem and Progenitor Cell Genomes.
Cell reports
Goldstein JM,Tabebordbar M,Zhu K,Wang LD,Messemer KA,Peacker B,Ashrafi Kakhki S,Gonzalez-Celeiro M,Shwartz Y,Cheng JKW,Xiao R,Barungi T,Albright C,Hsu YC,Vandenberghe LH,Wagers AJ
48-0452 was used in Flow cytometry/Cell sorting to demonstrate in vivo transduction of endogenous tissue stem cells in the muscle, blood, and skin by systemic or local administration of adeno-associated viruses (AAVs) encoding genome-modifying enzymes.
Tue Apr 23 00:00:00 EDT 2019
ImmGen report: sexual dimorphism in the immune system transcriptome.
Nature communications
Gal-Oz ST,Maier B,Yoshida H,Seddu K,Elbaz N,Czysz C,Zuk O,Stranger BE,Ner-Gaon H,Shay T
48-0452 was used in Flow cytometry/Cell sorting to show transcriptional sexual dimorphism in macrophages.
Fri Sep 20 00:00:00 EDT 2019
miR-21 Expression Determines the Early Vaccine Immunity Induced by LdCen-/- Immunization.
Frontiers in immunology
Gannavaram S,Bhattacharya P,Siddiqui A,Ismail N,Madhavan S,Nakhasi HL
48-0452-82 was used in Flow Cytometry to demonstrate that LdCen -/- infection suppresses miR-21 expression, enables IL12 mediated induction of adaptive immunity including proliferation of antigen experienced CD4+ T cells and development of a Th1 immunity, and suggest that miR-21 could be an important biomarker for LdCen -/- vaccine immunity in human clinical trials.
Mon Oct 26 00:00:00 EDT 2020
c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells.
Cell reports
Shikatani EA,Besla R,Ensan S,Upadhye A,Khyzha N,Li A,Emoto T,Chiu F,Degousee N,Moreau JM,Perry HM,Thayaparan D,Cheng HS,Pacheco S,Smyth D,Noyan H,Zavitz CCJ,Bauer CMT,Hilgendorf I,Libby P,Swirski FK,Gommerman JL,Fish JE,Stampfli MR,Cybulsky MI,Rubin BB,Paige CJ,Bender TP,McNamara CA,Husain M,Robbins CS
48-0452-82 was used in Flow Cytometry to identify the nuclear transcription factor c-Myb as an important mediator of atherosclerotic disease in mice.
Tue May 21 00:00:00 EDT 2019
K63-linked ubiquitination regulates RIPK1 kinase activity to prevent cell death during embryogenesis and inflammation.
Nature communications
Tang Y,Tu H,Zhang J,Zhao X,Wang Y,Qin J,Lin X
48-0452-82 was used in Flow Cytometry to reveal the mechanism by which K63-linked ubiquitination on K376 regulates RIPK1 kinase activity to control cell death programs.
Fri Sep 13 00:00:00 EDT 2019
Activated Peyer's patch B cells sample antigen directly from M cells in the subepithelial dome.
Nature communications
Komban RJ,Strömberg A,Biram A,Cervin J,Lebrero-Fernández C,Mabbott N,Yrlid U,Shulman Z,Bemark M,Lycke N
48-0452-82 was used in Immunohistochemistry to report a M cell-B cell antigen-specific transporting pathway in PP that is independent of DC. We propose that this antigen transporting pathway has a critical role in gut IgA responses, and should be taken into account when developing mucosal vaccines.
Mon Jun 03 00:00:00 EDT 2019
Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche.
Nature medicine
Maryanovich M,Zahalka AH,Pierce H,Pinho S,Nakahara F,Asada N,Wei Q,Wang X,Ciero P,Xu J,Leftin A,Frenette PS
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Fri Jun 01 00:00:00 EDT 2018
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation.
Immunity
Emgård J,Kammoun H,García-Cassani B,Chesné J,Parigi SM,Jacob JM,Cheng HW,Evren E,Das S,Czarnewski P,Sleiers N,Melo-Gonzalez F,Kvedaraite E,Svensson M,Scandella E,Hepworth MR,Huber S,Ludewig B,Peduto L,Villablanca EJ,Veiga-Fernandes H,Pereira JP,Flavell RA,Willinger T
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunofluorescence
Tue Jan 16 00:00:00 EST 2018
Cbl Ubiquitin Ligases Control B Cell Exit from the Germinal-Center Reaction.
Immunity
Li X,Gadzinsky A,Gong L,Tong H,Calderon V,Li Y,Kitamura D,Klein U,Langdon WY,Hou F,Zou YR,Gu H
48-0452-82 was used in Flow Cytometry to show that deleting E3 ubiquitin ligases Cbl and Cbl-b (Cbls) in GC B cells results in the early exit of high-affinity antigen-specific B cells from the GC reaction and thus impaired clonal expansion.
Tue Mar 20 00:00:00 EDT 2018
PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy.
Cell stem cell
Hsu JI,Dayaram T,Tovy A,De Braekeleer E,Jeong M,Wang F,Zhang J,Heffernan TP,Gera S,Kovacs JJ,Marszalek JR,Bristow C,Yan Y,Garcia-Manero G,Kantarjian H,Vassiliou G,Futreal PA,Donehower LA,Takahashi K,Goodell MA
48-0452 was used in Flow cytometry/Cell sorting to establish the clinical relevance of PPM1D mutations in clonal haematopoiesis and the importance of studying mutation-treatment interactions.
Thu Nov 01 00:00:00 EDT 2018
Human herpesvirus-encoded kinase induces B cell lymphomas in vivo.
The Journal of clinical investigation
Anders PM,Montgomery ND,Montgomery SA,Bhatt AP,Dittmer DP,Damania B
48-0452 was used in Flow cytometry/Cell sorting to analyse the function of viral protein kinase in vivo.
Fri Jun 01 00:00:00 EDT 2018
Microbial symbionts regulate the primary Ig repertoire.
The Journal of experimental medicine
Chen Y,Chaudhary N,Yang N,Granato A,Turner JA,Howard SL,Devereaux C,Zuo T,Shrestha A,Goel RR,Neuberg D,Wesemann DR
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunofluorescence
Mon May 07 00:00:00 EDT 2018
Nongenetic origins of cell-to-cell variability in B lymphocyte proliferation.
Proceedings of the National Academy of Sciences of the United States of America
Mitchell S,Roy K,Zangle TA,Hoffmann A
48-0452 was used in Flow cytometry/Cell sorting to characterise the role of molecular noise in determining phenotype heterogeneity.
Tue Mar 20 00:00:00 EDT 2018
Proapoptotic BIM Impacts B Lymphoid Homeostasis by Limiting the Survival of Mature B Cells in a Cell-Autonomous Manner.
Frontiers in immunology
Liu R,King A,Bouillet P,Tarlinton DM,Strasser A,Heierhorst J
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Wed May 01 00:00:00 EDT 2019
Thymic B Cell-Mediated Attack of Thymic Stroma Precedes Type 1 Diabetes Development.
Frontiers in immunology
Pinto AI,Smith J,Kissack MR,Hogg KG,Green EA
48-0452 was used in Flow cytometry/Cell sorting to suggest that the thymus may be a principal autoimmune target in T1D and contributes to disease progression.
Tue Aug 20 00:00:00 EDT 2019
Host Tumor Suppressor p18INK4c Functions as a Potent Cell-Intrinsic Inhibitor of Murine Gammaherpesvirus 68 Reactivation and Pathogenesis.
Journal of virology
Niemeyer BF,Oko LM,Medina EM,Oldenburg DG,White DW,Cool CD,Clambey ET,van Dyk LF
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Thu Mar 15 00:00:00 EDT 2018
Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Wang Y,Xiao M,Tao C,Chen J,Wang Z,Yang J,Chen Z,Zou Z,Liu A,Cai D,Jiang Y,Ding C,Li M,Bai X
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
Tanshinone IIA and Astragaloside IV promote the angiogenesis of mesenchymal stem cell-derived endothelial cell-like cells via upregulation of Cx37, Cx40 and Cx43.
Experimental and therapeutic medicine
Li Z,Zhang S,Cao L,Li W,Ye YC,Shi ZX,Wang ZR,Sun LX,Wang JW,Jia LT,Wang W
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Thu Feb 01 00:00:00 EST 2018
miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling.
Nature communications
Lam J,van den Bosch M,Wegrzyn J,Parker J,Ibrahim R,Slowski K,Chang L,Martinez-Høyer S,Condorelli G,Boldin M,Deng Y,Umlandt P,Fuller M,Karsan A
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Wed Jun 20 00:00:00 EDT 2018
Anti-inflammatory Effects of the Octapeptide NAP in Human Microbiota-Associated Mice Suffering from Subacute Ileitis.
European journal of microbiology & immunology
Escher U,Giladi E,Dunay IR,Bereswill S,Gozes I,Heimesaat MM
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry (Paraffin)
Mon Jun 25 00:00:00 EDT 2018
Dysregulated TRAF3 and BCL2 Expression Promotes Multiple Classes of Mature Non-hodgkin B Cell Lymphoma in Mice.
Frontiers in immunology
Perez-Chacon G,Adrados M,Vallejo-Cremades MT,Lefebvre S,Reed JC,Zapata JM
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Fri Oct 25 00:00:00 EDT 2019
ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases.
Frontiers in immunology
Glal D,Sudhakar JN,Lu HH,Liu MC,Chiang HY,Liu YC,Cheng CF,Shui JW
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Thu Sep 26 00:00:00 EDT 2019
The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport.
Immunity
Pelka K,Bertheloot D,Reimer E,Phulphagar K,Schmidt SV,Christ A,Stahl R,Watson N,Miyake K,Hacohen N,Haas A,Brinkmann MM,Marshak-Rothstein A,Meissner F,Latz E
48-0452-82 was used in Flow Cytometry to report that UNC93B1 regulates a step upstream of the differential TLR trafficking process.
Tue May 15 00:00:00 EDT 2018
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
48-0452 was used in Flow cytometry/Cell sorting to study paediatric acute myeloid leukaemia biology, and provide murine models that offer the potential for developing paediatric specific therapeutic strategies.
Tue Dec 11 00:00:00 EST 2018
Sphingosine-1-Phosphate Prevents Egress of Hematopoietic Stem Cells From Liver to Reduce Fibrosis.
Gastroenterology
King A,Houlihan DD,Kavanagh D,Haldar D,Luu N,Owen A,Suresh S,Than NN,Reynolds G,Penny J,Sumption H,Ramachandran P,Henderson NC,Kalia N,Frampton J,Adams DH,Newsome PN
48-0452 was used in Flow cytometry/Cell sorting to investigate the role of sphingosine-1-phosphate in the response of hematopoietic stem cells to liver fibrosis in mice.
Sat Jul 01 00:00:00 EDT 2017
Differential cytokine contributions of perivascular haematopoietic stem cell niches.
Nature cell biology
Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target.
Cell stem cell
Schneider RK,Mullally A,Dugourd A,Peisker F,Hoogenboezem R,Van Strien PMH,Bindels EM,Heckl D,Büsche G,Fleck D,Müller-Newen G,Wongboonsin J,Ventura Ferreira M,Puelles VG,Saez-Rodriguez J,Ebert BL,Humphreys BD,Kramann R
48-0452 was used in Flow cytometry/Cell sorting to study the cellular origin of bone marrow fibrosis.
Thu Jun 01 00:00:00 EDT 2017
Anti-tumor immunity of BAM-SiPc-mediated vascular photodynamic therapy in a BALB/c mouse model.
Cellular & molecular immunology
Yeung HY,Lo PC,Ng DK,Fong WP
48-0452 was used in Immunohistochemistry on paraffin embedded tissues to examine the role of both cell-mediated and humoural adaptive immune components in anti-cancer photodynamic therapy.
Wed Feb 01 00:00:00 EST 2017
Combined antiangiogenic and anti-PD-L1 therapy stimulates tumor immunity through HEV formation.
Science translational medicine
Allen E,Jabouille A,Rivera LB,Lodewijckx I,Missiaen R,Steri V,Feyen K,Tawney J,Hanahan D,Michael IP,Bergers G
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Wed Apr 12 00:00:00 EDT 2017
Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma.
The Journal of experimental medicine
Takahashi T,Asano Y,Sugawara K,Yamashita T,Nakamura K,Saigusa R,Ichimura Y,Toyama T,Taniguchi T,Akamata K,Noda S,Yoshizaki A,Tsuruta D,Trojanowska M,Sato S
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Mon Apr 03 00:00:00 EDT 2017
Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma.
The Journal of experimental medicine
Takahashi T,Asano Y,Sugawara K,Yamashita T,Nakamura K,Saigusa R,Ichimura Y,Toyama T,Taniguchi T,Akamata K,Noda S,Yoshizaki A,Tsuruta D,Trojanowska M,Sato S
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Mon Apr 03 00:00:00 EDT 2017
EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop.
Nature communications
Béguelin W,Rivas MA,Calvo Fernández MT,Teater M,Purwada A,Redmond D,Shen H,Challman MF,Elemento O,Singh A,Melnick AM
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Thu Oct 12 00:00:00 EDT 2017
DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice.
Nature communications
Ottina E,Peperzak V,Schoeler K,Carrington E,Sgonc R,Pellegrini M,Preston S,Herold MJ,Strasser A,Villunger A
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Wed Oct 18 00:00:00 EDT 2017
The Interleukin (IL)-1R1 pathway is a critical negative regulator of PyMT-mediated mammary tumorigenesis and pulmonary metastasis.
Oncoimmunology
Dagenais M,Dupaul-Chicoine J,Douglas T,Champagne C,Morizot A,Saleh M
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces.
JCI insight
Azzam KM,Madenspacher JH,Cain DW,Lai L,Gowdy KM,Rai P,Janardhan K,Clayton N,Cunningham W,Jensen H,Patel PS,Kearney JF,Taylor GA,Fessler MB
48-0452 was used in Flow cytometry/Cell sorting to investigate a novel model of Sjogren's syndrome.
Thu Aug 17 00:00:00 EDT 2017
Multiple functional therapeutic effects of TnP: A small stable synthetic peptide derived from fish venom in a mouse model of multiple sclerosis.
PloS one
Komegae EN,Souza TA,Grund LZ,Lima C,Lopes-Ferreira M
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Thu Aug 17 00:00:00 EDT 2017
Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis.
Immunity
Onder L,Mörbe U,Pikor N,Novkovic M,Cheng HW,Hehlgans T,Pfeffer K,Becher B,Waisman A,Rülicke T,Gommerman J,Mueller CG,Sawa S,Scandella E,Ludewig B
48-0452-82 was used in Flow Cytometry to find that initiation of LN development is dependent on LTi-cell-mediated activation of lymphatic endothelial cells (LECs) and that engagement of mesenchymal stromal cells is a succeeding event.
Tue Jul 18 00:00:00 EDT 2017
Regulation of type 1 diabetes development and B-cell activation in nonobese diabetic mice by early life exposure to a diabetogenic environment.
PloS one
De Riva A,Wållberg M,Ronchi F,Coulson R,Sage A,Thorne L,Goodfellow I,McCoy KD,Azuma M,Cooke A,Busch R
48-0452 was used in Flow cytometry/Cell sorting to investigate environmental and immunophenotypic differences between two nonobese diabetic (NOD) mouse colonies, NODlow and NODhigh, as well as the transmissibility of the colony differences in type 1 diabetes development.
Fri Oct 06 00:00:00 EDT 2017
Neutrophil swarming and extracellular trap formation play a significant role in Alum adjuvant activity.
NPJ vaccines
Stephen J,Scales HE,Benson RA,Erben D,Garside P,Brewer JM
48-0452 was used in Flow cytometry/Cell sorting to show that the very early injection site reaction is characterised by inflammatory chemokine production and neutrophil recruitment.
Fri Apr 08 00:00:00 EDT 2022
Group A Streptococcus intranasal infection promotes CNS infiltration by streptococcal-specific Th17 cells.
The Journal of clinical investigation
Dileepan T,Smith ED,Knowland D,Hsu M,Platt M,Bittner-Eddy P,Cohen B,Southern P,Latimer E,Harley E,Agalliu D,Cleary PP
48-0452 was used in Flow cytometry/Cell sorting to elucidate the immunopathological contribution of Group A streptococci (GAS)-specific CD4+ T cells in the induced neuropathology following infection with GAS.
Fri Jan 01 00:00:00 EST 2016
Soluble CD93 Is Involved in Metabolic Dysregulation but Does Not Influence Carotid Intima-Media Thickness.
Diabetes
Strawbridge RJ,Hilding A,Silveira A,Österholm C,Sennblad B,McLeod O,Tsikrika P,Foroogh F,Tremoli E,Baldassarre D,Veglia F,Rauramaa R,Smit AJ,Giral P,Kurl S,Mannarino E,Grossi E,Syvänen AC,Humphries SE,de Faire U,Östenson CG,Maegdefessel L,Hamsten A,Bäcklund A
48-0452 was used in Flow cytometry/Cell sorting to study the role of sCD93 in metabolic dysregulation of carotid intima-media thickness.
Sat Oct 01 00:00:00 EDT 2016
CD4 T Helper Cells Instruct Lymphopenia-Induced Memory-Like CD8 T Cells for Control of Acute LCMV Infection.
Frontiers in immunology
Schmitt ME,Sitte S,Voehringer D
48-0452 was used in Flow cytometry/Cell sorting to determine whether memory-like T cells can efficiently respond to foreign antigen and participate in antiviral immunity.
Wed Nov 20 00:00:00 EST 2019
Bmp signaling in colonic mesenchyme regulates stromal microenvironment and protects from polyposis initiation.
International journal of cancer
Allaire JM,Roy SA,Ouellet C,Lemieux É,Jones C,Paquet M,Boudreau F,Perreault N
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunofluorescence
Wed Jun 01 00:00:00 EDT 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Mon Aug 15 00:00:00 EDT 2016
Dendritic Cells Are Dispensable for T Cell Priming and Control of Acute Lymphocytic Choriomeningitis Virus Infection.
Journal of immunology (Baltimore, Md. : 1950)
Hilpert C,Sitte S,Matthies A,Voehringer D
48-0452 was used in Flow cytometry/Cell sorting to study the role of dendritic cells as antigen presenting cells and a source of type I interferons in acute lymphocytic choriomeningitis virus infection.
Sat Oct 01 00:00:00 EDT 2016
Contamination of DNase Preparations Confounds Analysis of the Role of DNA in Alum-Adjuvanted Vaccines.
Journal of immunology (Baltimore, Md. : 1950)
Noges LE,White J,Cambier JC,Kappler JW,Marrack P
48-0452 was used in Flow cytometry/Cell sorting to investigate the contribution of host DNA released at the site of vaccine injection to the adjuvant activity of alum.
Mon Aug 15 00:00:00 EDT 2016
Low dose of GRP78-targeting subtilase cytotoxin improves the efficacy of photodynamic therapy in vivo.
Oncology reports
Gabrysiak M,Wachowska M,Barankiewicz J,Pilch Z,Ratajska A,Skrzypek E,Winiarska M,Domagala A,Rygiel TP,Jozkowicz A,Boon L,Golab J,Firczuk M
48-0452 was used in Flow cytometry/Cell sorting to identify factors allowing for the most immunogenic response to photodynamic therapy.
Wed Jun 01 00:00:00 EDT 2016
Postnatal lethality and abnormal development of foregut and spleen in Ndrg4 mutant mice.
Biochemical and biophysical research communications
Qu X,Li J,Baldwin HS
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunofluorescence
Fri Feb 12 00:00:00 EST 2016
Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.
Stem cell reports
Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Tue Aug 09 00:00:00 EDT 2016
Regulation of Inflammation by IL-17A and IL-17F Modulates Non-Alcoholic Fatty Liver Disease Pathogenesis.
PloS one
Giles DA,Moreno-Fernandez ME,Stankiewicz TE,Cappelletti M,Huppert SS,Iwakura Y,Dong C,Shanmukhappa SK,Divanovic S
48-0452 was used in Flow cytometry/Cell sorting to indicate that the IL-17 axis also plays a role in a MCDD-induced model of NAFLD pathogenesis.
Tue Jul 19 00:00:00 EDT 2016
Efficient generation of monoclonal antibodies against peptide in the context of MHCII using magnetic enrichment.
Nature communications
Spanier JA,Frederick DR,Taylor JJ,Heffernan JR,Kotov DI,Martinov T,Osum KC,Ruggiero JL,Rust BJ,Landry SJ,Jenkins MK,McLachlan JB,Fife BT
48-0452 was used in Flow cytometry/Cell sorting to develop a novel approach for the generation and screening of peptide:MHCII reactive mAbs that exploits the use of recombinant peptide:MHC monomers as immunogens.
Mon Jun 13 00:00:00 EDT 2016
High Fat Diet Inhibits Dendritic Cell and T Cell Response to Allergens but Does Not Impair Inhalational Respiratory Tolerance.
PloS one
Pizzolla A,Oh DY,Luong S,Prickett SR,Henstridge DC,Febbraio MA,O'Hehir RE,Rolland JM,Hardy CL
48-0452 was used in Flow cytometry/Cell sorting to study the relationship between a high fat diet and allergic asthma using an induced-respiratory tolerance model in mice.
Wed Jul 26 00:00:00 EDT 2017
The microRNA miR-22 inhibits the histone deacetylase HDAC4 to promote T(H)17 cell-dependent emphysema.
Nature immunology
Lu W,You R,Yuan X,Yang T,Samuel EL,Marcano DC,Sikkema WK,Tour JM,Rodriguez A,Kheradmand F,Corry DB
48-0452 was used in Flow cytometry/Cell sorting to show that miR-22 expression was upregulated as a consequence of smoking and contributes to the development of emphysema.
Sun Nov 01 00:00:00 EDT 2015
Batf3 maintains autoactivation of Irf8 for commitment of a CD8α(+) conventional DC clonogenic progenitor.
Nature immunology
Grajales-Reyes GE,Iwata A,Albring J,Wu X,Tussiwand R,Kc W,Kretzer NM,Briseño CG,Durai V,Bagadia P,Haldar M,Schönheit J,Rosenbauer F,Murphy TL,Murphy KM
48-0452 was used in Flow cytometry/Cell sorting to investigate the role of the transcription factors Batf3 and IRF8 in the development of CD8α(+) conventional dendritic cells (cDCs)..
Wed Jul 01 00:00:00 EDT 2015
Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors.
The Journal of clinical investigation
Henry CJ,Casás-Selves M,Kim J,Zaberezhnyy V,Aghili L,Daniel AE,Jimenez L,Azam T,McNamee EN,Clambey ET,Klawitter J,Serkova NJ,Tan AC,Dinarello CA,DeGregori J
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2015
BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival.
The Journal of experimental medicine
Jacque E,Schweighoffer E,Tybulewicz VL,Ley SC
48-0452 was used in Flow cytometry/Cell sorting to reveal a potentially critical role for the MEK5-ERK5 MAP kinase signalling pathway in BAFF-induced mature B cell survival and homeostatic maintenance of B2 cell numbers.
Mon Jun 01 00:00:00 EDT 2015
MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice.
Proceedings of the National Academy of Sciences of the United States of America
Wu L,Li N,Zhang M,Xue SL,Cassady K,Lin Q,Riggs AD,Zeng D
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunofluorescence
Tue Dec 29 00:00:00 EST 2015
Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis.
Cell death and differentiation
Cho J,Seo J,Lim CH,Yang L,Shiratsuchi T,Lee MH,Chowdhury RR,Kasahara H,Kim JS,Oh SP,Lee YJ,Terada N
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
The immunosenescence-related gene Zizimin2 is associated with early bone marrow B cell development and marginal zone B cell formation.
Immunity & ageing : I & A
Matsuda T,Yanase S,Takaoka A,Maruyama M
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunofluorescence
Mon Mar 02 00:00:00 EST 2015
Antigen presentation kinetics control T cell/dendritic cell interactions and follicular helper T cell generation in vivo.
eLife
Benson RA,MacLeod MK,Hale BG,Patakas A,Garside P,Brewer JM
48-0452 was used in Flow cytometry/Cell sorting to investigate the conditions affecting follicular helper T cell differentiation and antigen presentation in an influenza infection model.
Mon Aug 10 00:00:00 EDT 2015
Nanoparticulate carbon black in cigarette smoke induces DNA cleavage and Th17-mediated emphysema.
eLife
You R,Lu W,Shan M,Berlin JM,Samuel EL,Marcano DC,Sun Z,Sikkema WK,Yuan X,Song L,Hendrix AY,Tour JM,Corry DB,Kheradmand F
48-0452 was used in Flow cytometry/Cell sorting to show that insoluble nanoparticulate carbon black accumulates in human myeloid dendritic cells (mDCs) from emphysematous lung and in CD11c(+) lung antigen presenting cells of mice exposed to smoke.
Mon Oct 05 00:00:00 EDT 2015
Early virus-host interactions dictate the course of a persistent infection.
PLoS pathogens
Sullivan BM,Teijaro JR,de la Torre JC,Oldstone MB
48-0452 was used in Flow cytometry/Cell sorting to investigate the very early host-virus interactions that determine the establishment of viral persistence.
Thu Jan 01 00:00:00 EST 2015
Syk tyrosine kinase is critical for B cell antibody responses and memory B cell survival.
Journal of immunology (Baltimore, Md. : 1950)
Ackermann JA,Nys J,Schweighoffer E,McCleary S,Smithers N,Tybulewicz VL
48-0452 was used in Flow cytometry/Cell sorting to define the contribution of Syk to B cell function.
Fri May 15 00:00:00 EDT 2015
Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance.
Carcinogenesis
Dabydeen SA,Kang K,Díaz-Cruz ES,Alamri A,Axelrod ML,Bouker KB,Al-Kharboosh R,Clarke R,Hennighausen L,Furth PA
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Thu Jan 01 00:00:00 EST 2015
Limited miR-17-92 overexpression drives hematologic malignancies.
Leukemia research
Danielson LS,Reavie L,Coussens M,Davalos V,Castillo-Martin M,Guijarro MV,Coffre M,Cordon-Cardo C,Aifantis I,Ibrahim S,Liu C,Koralov SB,Hernando E
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Sun Mar 01 00:00:00 EST 2015
Endothelial Gata5 transcription factor regulates blood pressure.
Nature communications
Messaoudi S,He Y,Gutsol A,Wight A,Hébert RL,Vilmundarson RO,Makrigiannis AP,Chalmers J,Hamet P,Tremblay J,McPherson R,Stewart AFR,Touyz RM,Nemer M
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Mon Nov 30 00:00:00 EST 2015
Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice.
Nature communications
Singh NK,Kotla S,Dyukova E,Traylor JG,Orr AW,Chernoff J,Marion TN,Rao GN
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Wed Jun 24 00:00:00 EDT 2015
KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR.
Nature communications
Kamimura D,Katsunuma K,Arima Y,Atsumi T,Jiang JJ,Bando H,Meng J,Sabharwal L,Stofkova A,Nishikawa N,Suzuki H,Ogura H,Ueda N,Tsuruoka M,Harada M,Kobayashi J,Hasegawa T,Yoshida H,Koseki H,Miura I,Wakana S,Nishida K,Kitamura H,Fukada T,Hirano T,Murakami M
48-0452 was used in Flow cytometry/Cell sorting to investigate the mechanism by which KDEL receptor 1 regulates the integration of stress responses in T cells.
Wed Jun 17 00:00:00 EDT 2015
Agonistic induction of PPARγ reverses cigarette smoke-induced emphysema.
The Journal of clinical investigation
Shan M,You R,Yuan X,Frazier MV,Porter P,Seryshev A,Hong JS,Song LZ,Zhang Y,Hilsenbeck S,Whitehead L,Zarinkamar N,Perusich S,Corry DB,Kheradmand F
48-0452 was used in Flow cytometry/Cell sorting to reveal a proinflammatory pathway, in which reduced PPARγ activity promotes emphysema.
Sat Mar 01 00:00:00 EST 2014
Group 2 innate lymphoid cells facilitate sensitization to local, but not systemic, TH2-inducing allergen exposures.
The Journal of allergy and clinical immunology
Gold MJ,Antignano F,Halim TY,Hirota JA,Blanchet MR,Zaph C,Takei F,McNagny KM
48-0452 was used in Flow cytometry/Cell sorting to reveal a critical role for ILC2s in the development of adaptive type 2 responses to local antigen exposure.
Tue Apr 01 00:00:00 EDT 2014
Transcription elongation factor ELL2 drives Ig secretory-specific mRNA production and the unfolded protein response.
Journal of immunology (Baltimore, Md. : 1950)
Park KS,Bayles I,Szlachta-McGinn A,Paul J,Boiko J,Santos P,Liu J,Wang Z,Borghesi L,Milcarek C
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Sat Nov 01 00:00:00 EDT 2014
IκBε is a key regulator of B cell expansion by providing negative feedback on cRel and RelA in a stimulus-specific manner.
Journal of immunology (Baltimore, Md. : 1950)
Alves BN,Tsui R,Almaden J,Shokhirev MN,Davis-Turak J,Fujimoto J,Birnbaum H,Ponomarenko J,Hoffmann A
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Tue Apr 01 00:00:00 EDT 2014
Chromosome instability underlies hematopoietic stem cell dysfunction and lymphoid neoplasia associated with impaired Fbw7-mediated cyclin E regulation.
Molecular and cellular biology
Siu KT,Xu Y,Swartz KL,Bhattacharyya M,Gurbuxani S,Hua Y,Minella AC
48-0452 was used in Flow cytometry/Cell sorting to investigate the contribution of individual substrate ubiquitination pathways to hematopoietic stem cell homeostasis, showing that impaired Fbw7-mediated cyclin E regulation leads to chromosome instability.
Mon Sep 01 00:00:00 EDT 2014
Rhof promotes murine marginal zone B cell development.
Nagoya journal of medical science
Kishimoto M,Matsuda T,Yanase S,Katsumi A,Suzuki N,Ikejiri M,Takagi A,Ikawa M,Kojima T,Kunishima S,Kiyoi H,Naoe T,Matsushita T,Maruyama M
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Fri Aug 01 00:00:00 EDT 2014
B-cell-intrinsic hepatitis C virus expression leads to B-cell-lymphomagenesis and induction of NF-κB signalling.
PloS one
Kasama Y,Mizukami T,Kusunoki H,Peveling-Oberhag J,Nishito Y,Ozawa M,Kohara M,Mizuochi T,Tsukiyama-Kohara K
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Mon Dec 22 00:00:00 EST 2014
B-cell-intrinsic hepatitis C virus expression leads to B-cell-lymphomagenesis and induction of NF-κB signalling.
PloS one
Kasama Y,Mizukami T,Kusunoki H,Peveling-Oberhag J,Nishito Y,Ozawa M,Kohara M,Mizuochi T,Tsukiyama-Kohara K
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Mon Dec 22 00:00:00 EST 2014
Genetic deletion of SEPT7 reveals a cell type-specific role of septins in microtubule destabilization for the completion of cytokinesis.
PLoS genetics
Menon MB,Sawada A,Chaturvedi A,Mishra P,Schuster-Gossler K,Galla M,Schambach A,Gossler A,Förster R,Heuser M,Kotlyarov A,Kinoshita M,Gaestel M
48-0452 was used in Flow cytometry/Cell sorting to reveal septins are essential for completion of mammalian cytokinesis in fibroblasts, but dispensable for cytokinesis in cells of the haematopoietic system.
Fri Aug 01 00:00:00 EDT 2014
Natural IgG antibodies provide innate protection against ficolin-opsonized bacteria.
The EMBO journal
Panda S,Zhang J,Tan NS,Ho B,Ding JL
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunofluorescence
Wed Nov 13 00:00:00 EST 2013
Reciprocal effects of rab7 deletion in activated and neglected T cells.
Autophagy
Roy SG,Stevens MW,So L,Edinger AL
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Mon Jul 01 00:00:00 EDT 2013
Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America
McKee AS,Burchill MA,Munks MW,Jin L,Kappler JW,Friedman RS,Jacobelli J,Marrack P
48-0452 was used in Flow cytometry/Cell sorting to study how aluminium acts as an adjuvant by introducing host DNA into the cytoplasm of dendritic cells, where it engages receptors promoting MHC II presentation.
Tue Mar 19 00:00:00 EDT 2013
A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis.
eLife
Olive V,Sabio E,Bennett MJ,De Jong CS,Biton A,McGann JC,Greaney SK,Sodir NM,Zhou AY,Balakrishnan A,Foth M,Luftig MA,Goga A,Speed TP,Xuan Z,Evan GI,Wan Y,Minella AC,He L
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Tue Oct 15 00:00:00 EDT 2013
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.
Development (Cambridge, England)
Liu B,Liu YF,Du YR,Mardaryev AN,Yang W,Chen H,Xu ZM,Xu CQ,Zhang XR,Botchkarev VA,Zhang Y,Xu GL
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunofluorescence
Fri Feb 01 00:00:00 EST 2013
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.
Development (Cambridge, England)
Liu B,Liu YF,Du YR,Mardaryev AN,Yang W,Chen H,Xu ZM,Xu CQ,Zhang XR,Botchkarev VA,Zhang Y,Xu GL
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunofluorescence
Fri Feb 01 00:00:00 EST 2013
Distinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells.
Development (Cambridge, England)
Tober J,Yzaguirre AD,Piwarzyk E,Speck NA
48-0452 was used in Flow cytometry/Cell sorting to study how the requirements for Runx1 in erythroid/myeloid progenitors and hematopoietic stem cell formation are temporally distinct.
Sun Sep 01 00:00:00 EDT 2013
CD22 is required for protection against West Nile virus Infection.
Journal of virology
Ma DY,Suthar MS,Kasahara S,Gale M,Clark EA
48-0452 was used in Flow cytometry/Cell sorting to elucidate the immunological requirements for an antibody response following West Nile virus infection.
Fri Mar 01 00:00:00 EST 2013
Differential uptake of nanoparticles and microparticles by pulmonary APC subsets induces discrete immunological imprints.
Journal of immunology (Baltimore, Md. : 1950)
Hardy CL,Lemasurier JS,Mohamud R,Yao J,Xiang SD,Rolland JM,O'Hehir RE,Plebanski M
48-0452 was used in Flow cytometry/Cell sorting to study the uptake of different sized particles by lung macrophages and dendritic cells.
Fri Nov 15 00:00:00 EST 2013
AID-expressing germinal center B cells cluster normally within lymph node follicles in the absence of FDC-M1+ CD35+ follicular dendritic cells but dissipate prematurely.
Journal of immunology (Baltimore, Md. : 1950)
Boulianne B,Le MX,Ward LA,Meng L,Haddad D,Li C,Martin A,Gommerman JL
48-0452 was used in Flow cytometry/Cell sorting to provide a spatial-temporal analysis of Ag-specific B cell activation and AID expression in the context of a peripheral lymph node that lacks FDC-M1(+) CD35(+) FDC and other LT-sensitive cell types.
Fri Nov 01 00:00:00 EDT 2013
Peptidoglycan recognition protein 1 enhances experimental asthma by promoting Th2 and Th17 and limiting regulatory T cell and plasmacytoid dendritic cell responses.
Journal of immunology (Baltimore, Md. : 1950)
Park SY,Jing X,Gupta D,Dziarski R
48-0452 was used in Flow cytometry/Cell sorting to demonstrate the proinflammatory effect of peptidoglycan recognition protein (Pglyrp)1 during the development of allergic asthma.
Mon Apr 01 00:00:00 EDT 2013
Identification of gingipain-specific I-A(b) -restricted CD4+ T cells following mucosal colonization with Porphyromonas gingivalis in C57BL/6 mice.
Molecular oral microbiology
Bittner-Eddy PD,Fischer LA,Costalonga M
48-0452 was used in Flow cytometry/Cell sorting to investigate whether MHC class II I-A(b) -binding peptides are presented to CD4(+) T cells during P. gingivalis oral colonisation.
Sun Dec 01 00:00:00 EST 2013
Neuronal and nonneuronal cholinergic structures in the mouse gastrointestinal tract and spleen.
The Journal of comparative neurology
Gautron L,Rutkowski JM,Burton MD,Wei W,Wan Y,Elmquist JK
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunofluorescence
Fri Nov 01 00:00:00 EDT 2013
TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo.
PLoS genetics
Gómez-Herreros F,Romero-Granados R,Zeng Z,Alvarez-Quilón A,Quintero C,Ju L,Umans L,Vermeire L,Huylebroeck D,Caldecott KW,Cortés-Ledesma F
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Thu Jun 13 00:00:00 EDT 2013
Bisphosphonates target B cells to enhance humoral immune responses.
Cell reports
Tonti E,Jiménez de Oya N,Galliverti G,Moseman EA,Di Lucia P,Amabile A,Sammicheli S,De Giovanni M,Sironi L,Chevrier N,Sitia G,Gennari L,Guidotti LG,von Andrian UH,Iannacone M
48-0452 was used in Flow cytometry/Cell sorting to demonstrate that the administration of clinically relevant doses of bisphosphonates in mice has an adjuvant effect.
Thu Oct 31 00:00:00 EDT 2013
DAP12 overexpression induces osteopenia and impaired early hematopoiesis.
PloS one
Despars G,Pandruvada SN,Anginot A,Domenget C,Jurdic P,Mazzorana M
48-0452 was used in Flow cytometry/Cell sorting to analyse the bone phenotype of mice overexpressing the human ITAM-bearing transmembrane signalling adaptor DAP12.
Thu Jan 16 00:00:00 EST 2014
Cigarette smoke induction of osteopontin (SPP1) mediates T(H)17 inflammation in human and experimental emphysema.
Science translational medicine
Shan M,Yuan X,Song LZ,Roberts L,Zarinkamar N,Seryshev A,Zhang Y,Hilsenbeck S,Chang SH,Dong C,Corry DB,Kheradmand F
48-0452 was used in Flow cytometry/Cell sorting to show that cigarette smoke increases the expression of IL-17A in both CD4+ and γδ T cells from mouse lung.
Wed Jan 18 00:00:00 EST 2012
Critical role of B cell lymphoma 10 in BAFF-regulated NF-κB activation and survival of anergic B cells.
Journal of immunology (Baltimore, Md. : 1950)
Yu M,Chen Y,He Y,Podd A,Fu G,Wright JA,Kleiman E,Khan WN,Wen R,Wang D
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2012
Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase.
Journal of immunology (Baltimore, Md. : 1950)
Hasham MG,Snow KJ,Donghia NM,Branca JA,Lessard MD,Stavnezer J,Shopland LS,Mills KD
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2012
Arthritogenic self-reactive CD4+ T cells acquire an FR4hiCD73hi anergic state in the presence of Foxp3+ regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Martinez RJ,Zhang N,Thomas SR,Nandiwada SL,Jenkins MK,Binstadt BA,Mueller DL
48-0452 was used in Flow cytometry/Cell sorting to suggest that autoimmune arthritis develops in the setting of lymphopenia when Foxp3(+)CD4(+) regulatory T cells are insufficient to functionally inactivate all autoreactive CD4(+) T cells that encounter self-Ag.
Sun Jan 01 00:00:00 EST 2012
CD28 promotes CD4+ T cell clonal expansion during infection independently of its YMNM and PYAP motifs.
Journal of immunology (Baltimore, Md. : 1950)
Pagán AJ,Pepper M,Chu HH,Green JM,Jenkins MK
48-0452 was used in Flow cytometry/Cell sorting to track polyclonal peptide:MHCII-specific CD4+ T cells in vivo, in mice with mutations in two sites within the cytoplasmic tail of CD28.
Sat Sep 15 00:00:00 EDT 2012
The specialized unfolded protein response of B lymphocytes: ATF6α-independent development of antibody-secreting B cells.
Molecular immunology
Aragon IV,Barrington RA,Jackowski S,Mori K,Brewer JW
48-0452 was used in Flow cytometry/Cell sorting to demonstrate that a specialised B cell UPR relies exclusively on the IRE1-XBP1 pathway to remodel the ER and expand secretory capacity.
Sun Jul 01 00:00:00 EDT 2012
Nuclear export of the NF-κB inhibitor IκBα is required for proper B cell and secondary lymphoid tissue formation.
Immunity
Wuerzberger-Davis SM,Chen Y,Yang DT,Kearns JD,Bates PW,Lynch C,Ladell NC,Yu M,Podd A,Zeng H,Huang TT,Wen R,Hoffmann A,Wang D,Miyamoto S
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Fri Feb 25 00:00:00 EST 2011
Nuclear export of the NF-κB inhibitor IκBα is required for proper B cell and secondary lymphoid tissue formation.
Immunity
Wuerzberger-Davis SM,Chen Y,Yang DT,Kearns JD,Bates PW,Lynch C,Ladell NC,Yu M,Podd A,Zeng H,Huang TT,Wen R,Hoffmann A,Wang D,Miyamoto S
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Immunohistochemistry
Fri Feb 25 00:00:00 EST 2011
Local renal autoantibody production in lupus nephritis.
Journal of the American Society of Nephrology : JASN
Espeli M,Bökers S,Giannico G,Dickinson HA,Bardsley V,Fogo AB,Smith KG
48-0452 was used in Flow cytometry/Cell sorting to identify the kidney as a major reservoir of autoreactive plasma cells in murine models of lupus nephritis that may contribute significantly to disease progression.
Tue Feb 01 00:00:00 EST 2011
PAD4-mediated neutrophil extracellular trap formation is not required for immunity against influenza infection.
PloS one
Hemmers S,Teijaro JR,Arandjelovic S,Mowen KA
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Tue Nov 15 00:00:00 EST 2011
A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation.
Blood
Schuman J,Chen Y,Podd A,Yu M,Liu HH,Wen R,Chen ZJ,Wang D
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Thu May 07 00:00:00 EDT 2009
p27 deficiency cooperates with Bcl-2 but not Bax to promote T-cell lymphoma.
PloS one
Cheng N,van de Wetering CI,Knudson CM
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Wed Apr 02 00:00:00 EDT 2008
Phospholipase Cgamma2 contributes to light-chain gene activation and receptor editing.
Molecular and cellular biology
Bai L,Chen Y,He Y,Dai X,Lin X,Wen R,Wang D
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2007
Essential role of phospholipase C gamma 2 in early B-cell development and Myc-mediated lymphomagenesis.
Molecular and cellular biology
Wen R,Chen Y,Bai L,Fu G,Schuman J,Dai X,Zeng H,Yang C,Stephan RP,Cleveland JL,Wang D
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2006
A role for brain-derived neurotrophic factor in B cell development.
Journal of neuroimmunology
Schuhmann B,Dietrich A,Sel S,Hahn C,Klingenspor M,Lommatzsch M,Gudermann T,Braun A,Renz H,Nockher WA
Wed Jun 01 00:00:00 EDT 2005
Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene.
Molecular and cellular biology
Pan L,Sato S,Frederick JP,Sun XH,Zhuang Y
Published figure using CD45R (B220) monoclonal antibody (Product # 48-0452-82) in Flow Cytometry
Wed Sep 01 00:00:00 EDT 1999
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-RA3-6B2-RE-AV-20170920122035.jpg?time=20220826?time=20220826 "CD45R (B220) Antibody (48-0452-82)")
