Product References
Cross-protective antibodies against common endemic respiratory viruses.
Nature communications
Cabán M,Rodarte JV,Bibby M,Gray MD,Taylor JJ,Pancera M,Boonyaratanakornkit J
25-0271-82 was used in Flow cytometry/Cell sorting to present the discovery, in vitro characterization, and in vivo efficacy testing of two cross-neutralizing monoclonal antibodies, one targeting both HPIV3 and HPIV1 and the other targeting both RSV and HMPV.
Mon Feb 13 00:00:00 EST 2023
Chronic CD27-CD70 costimulation promotes type 1-specific polarization of effector Tregs.
Frontiers in immunology
Bowakim-Anta N,Acolty V,Azouz A,Yagita H,Leo O,Goriely S,Oldenhove G,Moser M
25-0271-82 was used in Flow cytometry/Cell sorting to conclude that CD27 may regulate the development of Th1 immunity in peripheral tissues as well as the subsequent switch of the effector response into long-term memory.
Thu Apr 06 00:00:00 EDT 2023
The transcription factor Bach2 negatively regulates murine natural killer cell maturation and function.
eLife
Li S,Bern MD,Miao B,Fan C,Xing X,Inoue T,Piersma SJ,Wang T,Colonna M,Kurosaki T,Yokoyama WM
Published figure using CD27 monoclonal antibody (Product # 25-0271-82) in Flow Cytometry
Mon Oct 03 00:00:00 EDT 2022
The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude.
The Journal of experimental medicine
Li ZY,Morman RE,Hegermiller E,Sun M,Bartom ET,Maienschein-Cline M,Sigvardsson M,Kee BL
Published figure using CD27 monoclonal antibody (Product # 25-0271-82) in Flow Cytometry
Mon Jun 07 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using CD27 monoclonal antibody (Product # 25-0271-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory.
Cell reports
Cannons JL,Villarino AV,Kapnick SM,Preite S,Shih HY,Gomez-Rodriguez J,Kaul Z,Shibata H,Reilley JM,Huang B,Handon R,McBain IT,Gossa S,Wu T,Su HC,McGavern DB,O'Shea JJ,McGuire PJ,Uzel G,Schwartzberg PL
Published figure using CD27 monoclonal antibody (Product # 25-0271-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Effect of Subcutaneous Anti-CD20 Antibody-Mediated B Cell Depletion on Susceptibility to Pneumocystis Infection in Mice.
mSphere
Dai G,Noell K,Weckbecker G,Kolls JK
Published figure using CD27 monoclonal antibody (Product # 25-0271-82) in Flow Cytometry
Wed May 05 00:00:00 EDT 2021
Immune cell phenotypes associated with disease severity and long-term neutralizing antibody titers after natural dengue virus infection.
Cell reports. Medicine
Rouers A,Chng MHY,Lee B,Rajapakse MP,Kaur K,Toh YX,Sathiakumar D,Loy T,Thein TL,Lim VWX,Singhal A,Yeo TW,Leo YS,Vora KA,Casimiro D,Lim B,Tucker-Kellogg L,Rivino L,Newell EW,Fink K
Published figure using CD27 monoclonal antibody (Product # 25-0271-82) in Flow Cytometry
Tue May 18 00:00:00 EDT 2021
Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies.
Cell reports
Seydoux E,Wan YH,Feng J,Wall A,Aljedani S,Homad LJ,MacCamy AJ,Weidle C,Gray MD,Brumage L,Taylor JJ,Pancera M,Stamatatos L,McGuire AT
25-0271-82 was used in Flow Cytometry to characterize a panel of anti-idiotypic monoclonal antibodies (ai-mAbs) raised against inferred-germline (iGL) VRC01-class antibodies.
Tue May 04 00:00:00 EDT 2021
Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies.
Cell reports
Seydoux E,Wan YH,Feng J,Wall A,Aljedani S,Homad LJ,MacCamy AJ,Weidle C,Gray MD,Brumage L,Taylor JJ,Pancera M,Stamatatos L,McGuire AT
25-0271-82 was used in Flow Cytometry to characterize a panel of anti-idiotypic monoclonal antibodies (ai-mAbs) raised against inferred-germline (iGL) VRC01-class antibodies.
Tue May 04 00:00:00 EDT 2021
Ontogenic timing, T cell receptor signal strength, and Notch signaling direct γδ T cell functional differentiation in vivo.
Cell reports
Chen ELY,Lee CR,Thompson PK,Wiest DL,Anderson MK,Zúñiga-Pflücker JC
Published figure using CD27 monoclonal antibody (Product # 25-0271-82) in Flow Cytometry
Tue Jun 08 00:00:00 EDT 2021
Interleukin-17A Serves a Priming Role in Autoimmunity by Recruiting IL-1β-Producing Myeloid Cells that Promote Pathogenic T Cells.
Immunity
McGinley AM,Sutton CE,Edwards SC,Leane CM,DeCourcey J,Teijeiro A,Hamilton JA,Boon L,Djouder N,Mills KHG
25-0271 was used in Flow cytometry/Cell sorting to demonstrate that a key function of IL-17A in central nervous system (CNS) autoimmunity is to recruit IL-1β-secreting myeloid cells that prime pathogenic γδT17 and Th17 cells.
Tue Feb 18 00:00:00 EST 2020
Th2 Biased Immunity With Altered B Cell Profiles in Circulation of Patients With Sporotrichosis Caused by Sporothrix globosa.
Frontiers in immunology
Zu J,Yao L,Song Y,Cui Y,Guan M,Chen R,Zhen Y,Li S
Published figure using CD27 monoclonal antibody (Product # 25-0271-82) in Flow Cytometry
Mon May 31 00:00:00 EDT 2021
Stage-Specific Requirement for Eomes in Mature NK Cell Homeostasis and Cytotoxicity.
Cell reports
Wagner JA,Wong P,Schappe T,Berrien-Elliott MM,Cubitt C,Jaeger N,Lee M,Keppel CR,Marin ND,Foltz JA,Marsala L,Neal CC,Sullivan RP,Schneider SE,Keppel MP,Saucier N,Cooper MA,Fehniger TA
25-0271 was used in Flow cytometry/Cell sorting to develop a tamoxifen-inducible, type-1-ILC-specific (Ncr1-targeted) cre mouse and combine this with Eomes-floxed mice.
Tue Jun 02 00:00:00 EDT 2020
CD4+ T Cell Fate Decisions Are Stochastic, Precede Cell Division, Depend on GITR Co-Stimulation, and Are Associated With Uropodium Development.
Frontiers in immunology
Cobbold SP,Adams E,Howie D,Waldmann H
25-0271 was used in Flow cytometry/Cell sorting to develop an in vitro model of T cell differentiation suited to testing how manipulation of components of the microenvironment might be therapeutically exploited.
Mon Jan 31 00:00:00 EST 2022
BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data.
Genome medicine
Upadhyay AA,Kauffman RC,Wolabaugh AN,Cho A,Patel NB,Reiss SM,Havenar-Daughton C,Dawoud RA,Tharp GK,Sanz I,Pulendran B,Crotty S,Lee FE,Wrammert J,Bosinger SE
Published figure using CD27 monoclonal antibody (Product # 25-0271-82) in Flow Cytometry
Tue Mar 20 00:00:00 EDT 2018
Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function.
Nature communications
Wang F,Meng M,Mo B,Yang Y,Ji Y,Huang P,Lai W,Pan X,You T,Luo H,Guan X,Deng Y,Yuan S,Chu J,Namaka M,Hughes T,Ye L,Yu J,Li X,Deng Y
Published figure using CD27 monoclonal antibody (Product # 25-0271-82) in Flow Cytometry
Mon Nov 19 00:00:00 EST 2018
FHL2 Regulates Natural Killer Cell Development and Activation during Streptococcus pneumoniae Infection.
Frontiers in immunology
Baranek T,Morello E,Valayer A,Aimar RF,Bréa D,Henry C,Besnard AG,Dalloneau E,Guillon A,Dequin PF,Narni-Mancinelli E,Vivier E,Laurent F,Wei Y,Paget C,Si-Tahar M
25-0271 was used in Flow cytometry/Cell sorting to determine the expression and role of FHL2 in natural killer cell biology.
Wed Nov 20 00:00:00 EST 2019
Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages.
Oncoimmunology
Kersten K,Coffelt SB,Hoogstraat M,Verstegen NJM,Vrijland K,Ciampricotti M,Doornebal CW,Hau CS,Wellenstein MD,Salvagno C,Doshi P,Lips EH,Wessels LFA,de Visser KE
25-0271 was used in Flow cytometry/Cell sorting to demonstrate mammary tumor-derived CCL2 can facilitate the breast cancer-induced pro-metastatic systemic inflammatory gamma delta T cell-IL17-neutrophil axis.
Sat Jan 29 00:00:00 EST 2022
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using CD27 monoclonal antibody (Product # 25-0271-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Nature communications
Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z
Published figure using CD27 monoclonal antibody (Product # 25-0271-82) in Flow Cytometry
Wed Sep 07 00:00:00 EDT 2016
Production of IL-10 by CD4(+) regulatory T cells during the resolution of infection promotes the maturation of memory CD8(+) T cells.
Nature immunology
Laidlaw BJ,Cui W,Amezquita RA,Gray SM,Guan T,Lu Y,Kobayashi Y,Flavell RA,Kleinstein SH,Craft J,Kaech SM
Published figure using CD27 monoclonal antibody (Product # 25-0271-82) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2015
PD-1+Tim-3+ CD8+ T Lymphocytes Display Varied Degrees of Functional Exhaustion in Patients with Regionally Metastatic Differentiated Thyroid Cancer.
Cancer immunology research
Severson JJ,Serracino HS,Mateescu V,Raeburn CD,McIntyre RC,Sams SB,Haugen BR,French JD
25-0271 was used in Flow cytometry/Cell sorting to determine that the release of PD-1 and Tim-3, and the inhibition of Tregs, may encourage tumour elimination in metastatic differentiated thyroid cancer.
Mon Jun 01 00:00:00 EDT 2015
Activated NKT cells imprint NK-cell differentiation, functionality and education.
European journal of immunology
Riese P,Trittel S,May T,Cicin-Sain L,Chambers BJ,Guzmán CA
25-0271 was used in Flow cytometry/Cell sorting to study the cellular cross-talk between natural killer T cells and natural killer cells.
Mon Jun 01 00:00:00 EDT 2015
The tyrosine phosphatase PTPN22 discriminates weak self peptides from strong agonist TCR signals.
Nature immunology
Salmond RJ,Brownlie RJ,Morrison VL,Zamoyska R
25-0271 was used in Flow cytometry/Cell sorting to study how loss-of-function PTPN22 alleles can lead to the population expansion of effector and/or memory T cells and a predisposition to human autoimmunity.
Mon Sep 01 00:00:00 EDT 2014
Type I interferon signaling enhances CD8+ T cell effector function and differentiation during murine gammaherpesvirus 68 infection.
Journal of virology
Jennings RN,Grayson JM,Barton ES
25-0271 was used in Flow cytometry/Cell sorting to assess T cell responses in IFNAR1(-/-) mice after MHV68 infection.
Mon Dec 01 00:00:00 EST 2014
Human γδ thymocytes are functionally immature and differentiate into cytotoxic type 1 effector T cells upon IL-2/IL-15 signaling.
Journal of immunology (Baltimore, Md. : 1950)
Ribot JC,Ribeiro ST,Correia DV,Sousa AE,Silva-Santos B
25-0271 was used in Flow cytometry/Cell sorting to study how ex vivo-isolated γδ thymocytes produced negligible IFN-γ and lacked cytolytic activity against leukemia cells.
Sat Mar 01 00:00:00 EST 2014
Plasmacytoid dendritic cells are scarcely represented in the human gut mucosa and are not recruited to the celiac lesion.
Mucosal immunology
Ráki M,Beitnes AC,Lundin KE,Jahnsen J,Jahnsen FL,Sollid LM
25-0271 was used in Flow cytometry/Cell sorting to suggest that IFN-α is present in the celiac mucosa and IFN-λ is important in intestinal antiviral defense.
Sun Sep 01 00:00:00 EDT 2013
Markers of nonselective and specific NK cell activation.
Journal of immunology (Baltimore, Md. : 1950)
Fogel LA,Sun MM,Geurs TL,Carayannopoulos LN,French AR
25-0271 was used in Flow cytometry/Cell sorting to demonstrate that a combination of Sca-1, CD27, and KLRG1 can distinguish NK cells based on their mechanism of activation.
Sat Jun 15 00:00:00 EDT 2013
Programmed death-1+ T cells and regulatory T cells are enriched in tumor-involved lymph nodes and associated with aggressive features in papillary thyroid cancer.
The Journal of clinical endocrinology and metabolism
French JD,Kotnis GR,Said S,Raeburn CD,McIntyre RC,Klopper JP,Haugen BR
25-0271 was used in Flow cytometry/Cell sorting to characterise the CD4(+) T cell response to metastatic PTC.
Fri Jun 01 00:00:00 EDT 2012