Product References
Cathepsin S inhibition in dendritic cells prevents Th17 cell differentiation in perivascular adipose tissues following vascular injury in diabetic rats.
Journal of biochemical and molecular toxicology
Peng H,Lv Y,Li C,Cheng Z,He S,Wang C,Liu J
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2023
Rapamycin improves Graves' orbitopathy by suppressing CD4+ cytotoxic T lymphocytes.
JCI insight
Zhang M,Chong KK,Chen ZY,Guo H,Liu YF,Kang YY,Li YJ,Shi TT,Lai KK,He MQ,Ye K,Kahaly GJ,Shi BY,Wang Y
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Wed Feb 08 00:00:00 EST 2023
Recurrent visceral leishmaniasis relapses in HIV co-infected patients are characterized by less efficient immune responses and higher parasite load.
iScience
Takele Y,Mulaw T,Adem E,Womersley R,Kaforou M,Franssen SU,Levin M,Taylor GP,Müller I,Cotton JA,Kropf P
11-0049-80 was used in Flow cytometry/Cell sorting to show that the relapse-free survival in patients with recurrent VL/HIV was shorter, that they had higher parasite load, lower weight gain, and lower recovery of all blood cell lineages.
Fri Feb 17 00:00:00 EST 2023
Serum amyloid a, C-reactive protein, and procalcitonin levels in children with Mycoplasma pneumoniae infection.
Journal of clinical laboratory analysis
Jiang Y,Wang W,Zhang Z,Ma X,Sang Y,Wang J,Xu G,Feng Q,Zhao S
11-0049-80 was used in T-Cell Activation to show that SAA, CRP, and PCT were specific markers for diagnosing early MP infection in children.
Tue Mar 01 00:00:00 EST 2022
Induced Human Regulatory T Cells Express the Glucagon-like Peptide-1 Receptor.
Cells
Rode AKO,Buus TB,Mraz V,Al-Jaberi FAH,Lopez DV,Ford SL,Hennen S,Eliasen IP,Klewe IV,Gharehdaghi L,Dragan A,Rosenkilde MM,Woetmann A,Skov L,Ødum N,Bonefeld CM,Kongsbak-Wismann M,Geisler C
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Immunohistochemistry (Paraffin)
Fri Aug 19 00:00:00 EDT 2022
Single-cell RNA sequencing reveals the molecular features of peripheral blood immune cells in children, adults and centenarians.
Frontiers in immunology
Zhong J,Ding R,Jiang H,Li L,Wan J,Feng X,Chen M,Peng L,Li X,Lin J,Yang H,Wang M,Li Q,Chen Q
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Mon Jan 30 00:00:00 EST 2023
Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunity.
Nature communications
McEvoy CM,Murphy JM,Zhang L,Clotet-Freixas S,Mathews JA,An J,Karimzadeh M,Pouyabahar D,Su S,Zaslaver O,Röst H,Arambewela R,Liu LY,Zhang S,Lawson KA,Finelli A,Wang B,MacParland SA,Bader GD,Konvalinka A,Crome SQ
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Sat Dec 10 00:00:00 EST 2022
Decoding the pathogenesis of Diamond-Blackfan anemia using single-cell RNA-seq.
Cell discovery
Wang B,Wang C,Wan Y,Gao J,Ma Y,Zhang Y,Tong J,Zhang Y,Liu J,Chang L,Xu C,Shen B,Chen Y,Jiang E,Kurita R,Nakamura Y,Lim KC,Engel JD,Zhou J,Cheng T,Zhu X,Zhu P,Shi L
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Tue May 10 00:00:00 EDT 2022
Immunological factors, but not clinical features, predict visceral leishmaniasis relapse in patients co-infected with HIV.
Cell reports. Medicine
Takele Y,Mulaw T,Adem E,Shaw CJ,Franssen SU,Womersley R,Kaforou M,Taylor GP,Levin M,Müller I,Cotton JA,Kropf P
11-0049-80 was used in Flow Cytometry to identify three immunological markers associated with visceral leishmaniasis relapse in VL/HIV patients.
Tue Jan 18 00:00:00 EST 2022
Effects of the Antidiabetic Drugs Evogliptin and Sitagliptin on the Immune Function of CD26/DPP4 in Th1 Cells.
Biomolecules & therapeutics
Yoon H,Sung JH,Song MJ
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2021
Murlentamab, a Low Fucosylated Anti-Müllerian Hormone Type II Receptor (AMHRII) Antibody, Exhibits Anti-Tumor Activity through Tumor-Associated Macrophage Reprogrammation and T Cell Activation.
Cancers
Prat M,Salon M,Allain T,Dubreuil O,Noël G,Preisser L,Jean B,Cassard L,Lemée F,Tabah-Fish I,Pipy B,Jeannin P,Prost JF,Barret JM,Coste A
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Tue Apr 13 00:00:00 EDT 2021
Characterization and modulation of anti-αβTCR antibodies and their respective binding sites at the βTCR chain to enrich engineered T cells.
Molecular therapy. Methods & clinical development
Kierkels GJJ,van Diest E,Hernández-López P,Scheper W,de Bruin ACM,Frijlink E,Aarts-Riemens T,van Dooremalen SFJ,Beringer DX,Oostvogels R,Kramer L,Straetemans T,Uckert W,Sebestyén Z,Kuball J
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Fri Sep 10 00:00:00 EDT 2021
Bispecific T-Cell Engaging Antibodies Against MUC16 Demonstrate Efficacy Against Ovarian Cancer in Monotherapy and in Combination With PD-1 and VEGF Inhibition.
Frontiers in immunology
Yeku OO,Rao TD,Laster I,Kononenko A,Purdon TJ,Wang P,Cui Z,Liu H,Brentjens RJ,Spriggs D
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Thu Oct 21 00:00:00 EDT 2021
Identification of two HLA-A*0201 immunogenic epitopes of lactate dehydrogenase C (LDHC): potential novel targets for cancer immunotherapy.
Cancer immunology, immunotherapy : CII
Thomas R,Shaath H,Naik A,Toor SM,Elkord E,Decock J
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2020
HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment.
Journal of Cancer
Kim YD,Park SM,Ha HC,Lee AR,Won H,Cha H,Cho S,Cho JM
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
Involvement of natural killer cells in the pathogenesis of endometriosis in patients with pelvic pain.
The Journal of international medical research
He J,Xu Y,Yi M,Gu C,Zhu Y,Hu G
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2020
Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells.
Frontiers in immunology
Møller SH,Mellergaard M,Madsen M,Bermejo AV,Jepsen SD,Hansen MH,Høgh RI,Aldana BI,Desler C,Rasmussen LJ,Sustarsic EG,Gerhart-Hines Z,Daskalaki E,Wheelock CE,Hiron TK,Lin D,O'Callaghan CA,Wandall HH,Andresen L,Skov S
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Neutralization
Fri Apr 30 00:00:00 EDT 2021
Standardized 11-color flow cytometry panel for the functional phenotyping of human T regulatory cells.
Journal of biological methods
Manuszak C,Brainard M,Thrash E,Hodi FS,Severgnini M
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
MicroRNA‑155 inhibits the proliferation of CD8+ T cells via upregulating regulatory T cells in vitiligo.
Molecular medicine reports
Lv M,Li Z,Liu J,Lin F,Zhang Q,Li Z,Wang Y,Wang K,Xu Y
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses.
Cell
Bradley T,Peppa D,Pedroza-Pacheco I,Li D,Cain DW,Henao R,Venkat V,Hora B,Chen Y,Vandergrift NA,Overman RG,Edwards RW,Woods CW,Tomaras GD,Ferrari G,Ginsburg GS,Connors M,Cohen MS,Moody MA,Borrow P,Haynes BF
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Thu Oct 04 00:00:00 EDT 2018
The Effects of High Mobility Group Box-1 Protein on Peripheral Treg/Th17 Balance in Patients with Atherosclerosis.
Acta Cardiologica Sinica
Ding JW,Zhou T,Zheng XX,Wang XA,Tong XH,Luo CY,Zhang ZQ,Yu B
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
Non-neutralizing Antibodies Alter the Course of HIV-1 Infection In Vivo.
Cell
Horwitz JA,Bar-On Y,Lu CL,Fera D,Lockhart AAK,Lorenzi JCC,Nogueira L,Golijanin J,Scheid JF,Seaman MS,Gazumyan A,Zolla-Pazner S,Nussenzweig MC
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Thu Aug 10 00:00:00 EDT 2017
Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer.
Cell research
Su S,Liao J,Liu J,Huang D,He C,Chen F,Yang L,Wu W,Chen J,Lin L,Zeng Y,Ouyang N,Cui X,Yao H,Su F,Huang JD,Lieberman J,Liu Q,Song E
11-0049 was used in Flow cytometry/Cell sorting to demonstrate that blocking PITPNM3 recognition of CCL18 could be an attractive immunotherapy aproach for treating breast cancer.
Sat Apr 01 00:00:00 EDT 2017
Impact of Enhancer of Zeste Homolog 2 on T Helper Cell-Mediated Allergic Rhinitis.
Frontiers in immunology
Hou TY,Chen MR,Chou YC,Kan PC,Tsai YT,Cha TL
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Protein kinase CK2 controls T-cell polarization through dendritic cell activation in response to contact sensitizers.
Journal of leukocyte biology
de Bourayne M,Gallais Y,El Ali Z,Rousseau P,Damiens MH,Cochet C,Filhol O,Chollet-Martin S,Pallardy M,Kerdine-Römer S
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
CXCL13-producing TFH cells link immune suppression and adaptive memory in human breast cancer.
JCI insight
Gu-Trantien C,Migliori E,Buisseret L,de Wind A,Brohée S,Garaud S,Noël G,Dang Chi VL,Lodewyckx JN,Naveaux C,Duvillier H,Goriely S,Larsimont D,Willard-Gallo K
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Fri Jun 02 00:00:00 EDT 2017
Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions.
Proceedings of the National Academy of Sciences of the United States of America
Jönsson P,Southcombe JH,Santos AM,Huo J,Fernandes RA,McColl J,Lever M,Evans EJ,Hudson A,Chang VT,Hanke T,Godkin A,Dunne PD,Horrocks MH,Palayret M,Screaton GR,Petersen J,Rossjohn J,Fugger L,Dushek O,Xu XN,Davis SJ,Klenerman D
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Immunofluorescence
Tue May 17 00:00:00 EDT 2016
Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions.
Proceedings of the National Academy of Sciences of the United States of America
Jönsson P,Southcombe JH,Santos AM,Huo J,Fernandes RA,McColl J,Lever M,Evans EJ,Hudson A,Chang VT,Hanke T,Godkin A,Dunne PD,Horrocks MH,Palayret M,Screaton GR,Petersen J,Rossjohn J,Fugger L,Dushek O,Xu XN,Davis SJ,Klenerman D
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Immunofluorescence
Tue May 17 00:00:00 EDT 2016
Interaction among activated lymphocytes and mesenchymal cells through podoplanin is critical for a high IL-17 secretion.
Arthritis research & therapy
Noack M,Ndongo-Thiam N,Miossec P
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Thu Jun 23 00:00:00 EDT 2016
CD28 family of receptors on T cells in chronic HBV infection: Expression characteristics, clinical significance and correlations with PD-1 blockade.
Molecular medicine reports
Tang ZS,Hao YH,Zhang EJ,Xu CL,Zhou Y,Zheng X,Yang DL
11-0049 was used in Flow cytometry/Cell sorting to investigate the expression characteristics and clinical significance of CD28, PD-1, CTLA4 and BTLA on T-cells in patients with chronic HBV and the correlations among these receptors.
Mon Aug 01 00:00:00 EDT 2016
Equilibrium of Treg/Th17 cells of peripheral blood in syphilitic patients with sero-resistance.
Experimental and therapeutic medicine
Zhao J,Ma J,Zhang X,Li Q,Yang X
11-0049 was used in Flow cytometry/Cell sorting to examine the proportions of Treg and Th17 cells in the peripheral blood, and their expression of specific transcription factors, in sero-resistant syphilitic patients and healthy donors.
Wed Jun 01 00:00:00 EDT 2016
Tuning of AKT-pathway by Nef and its blockade by protease inhibitors results in limited recovery in latently HIV infected T-cell line.
Scientific reports
Kumar A,Abbas W,Colin L,Khan KA,Bouchat S,Varin A,Larbi A,Gatot JS,Kabeya K,Vanhulle C,Delacourt N,Pasquereau S,Coquard L,Borch A,König R,Clumeck N,De Wit S,Rohr O,Rouzioux C,Fulop T,Van Lint C,Herbein G
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Thu Apr 14 00:00:00 EDT 2016
Lack of T Cell Response to iPSC-Derived Retinal Pigment Epithelial Cells from HLA Homozygous Donors.
Stem cell reports
Sugita S,Iwasaki Y,Makabe K,Kimura T,Futagami T,Suegami S,Takahashi M
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Tue Oct 11 00:00:00 EDT 2016
Heterologous Immunity between Adenoviruses and Hepatitis C Virus: A New Paradigm in HCV Immunity and Vaccines.
PloS one
Singh S,Vedi S,Samrat SK,Li W,Kumar R,Agrawal B
11-0049 was used in Flow cytometry/Cell sorting to investigate the potential of a previously uncharacterized property of natural human adenovirus infection to dictate, modulate and/or alter the course of HCV infection upon exposure.
Tue Jul 19 00:00:00 EDT 2016
Pathological Roles of Interleukin-22 in the Development of Recurrent Hepatitis C after Liver Transplantation.
PloS one
Gao Y,Ren H,Meng F,Li J,Cheung E,Li H,Zhao J,Liu H,Liu Z,Zhang M
11-0049 was used in Flow cytometry/Cell sorting to investigate the role of interleukin-22-producing CD4 positive cells in the pathogenesis of Hepatitis C Virus recurrence after Orthotopic Liver Transplantation.
Fri Mar 24 00:00:00 EDT 2017
Antitumor immunity triggered by melphalan is potentiated by melanoma cell surface-associated calreticulin.
Cancer research
Dudek-Perić AM,Ferreira GB,Muchowicz A,Wouters J,Prada N,Martin S,Kiviluoto S,Winiarska M,Boon L,Mathieu C,van den Oord J,Stas M,Gougeon ML,Golab J,Garg AD,Agostinis P
11-0049 was used in Flow cytometry/Cell sorting to illustrate how melphalan triggers inflammatory cell death that can be leveraged by immunomodulators.
Wed Apr 15 00:00:00 EDT 2015
PD-1+Tim-3+ CD8+ T Lymphocytes Display Varied Degrees of Functional Exhaustion in Patients with Regionally Metastatic Differentiated Thyroid Cancer.
Cancer immunology research
Severson JJ,Serracino HS,Mateescu V,Raeburn CD,McIntyre RC,Sams SB,Haugen BR,French JD
11-0049 was used in Flow cytometry/Cell sorting to determine that the release of PD-1 and Tim-3, and the inhibition of Tregs, may encourage tumour elimination in metastatic differentiated thyroid cancer.
Mon Jun 01 00:00:00 EDT 2015
Levels and function of regulatory T cells in patients with polymorphic light eruption: relation to photohardening.
The British journal of dermatology
Schweintzger N,Gruber-Wackernagel A,Reginato E,Bambach I,Quehenberger F,Byrne SN,Wolf P
11-0049 was used in Flow cytometry/Cell sorting to investigate how a UV-induced increase in the number of Tregs may be a mechanism by which the immune system counteracts susceptibility to PLE.
Sat Aug 01 00:00:00 EDT 2015
CARD9-Dependent Neutrophil Recruitment Protects against Fungal Invasion of the Central Nervous System.
PLoS pathogens
Drummond RA,Collar AL,Swamydas M,Rodriguez CA,Lim JK,Mendez LM,Fink DL,Hsu AP,Zhai B,Karauzum H,Mikelis CM,Rose SR,Ferre EM,Yockey L,Lemberg K,Kuehn HS,Rosenzweig SD,Lin X,Chittiboina P,Datta SK,Belhorn TH,Weimer ET,Hernandez ML,Hohl TM,Kuhns DB,Lionakis MS
11-0049 was used in Flow cytometry/Cell sorting to highlight the role of CARD9-dependant neutrophil trafficking into the CNS and provide insight into the CNS fungal susceptibility of CARD9-deficient humans.
Tue Dec 01 00:00:00 EST 2015
Synovial Regulatory T Cells Occupy a Discrete TCR Niche in Human Arthritis and Require Local Signals To Stabilize FOXP3 Protein Expression.
Journal of immunology (Baltimore, Md. : 1950)
Bending D,Giannakopoulou E,Lom H,Wedderburn LR
11-0049 was used in Flow cytometry/Cell sorting to identify a unique population of Treg cells which arise from separate lineages to conventional T cells in response to chronic inflammatory conditions.
Tue Dec 15 00:00:00 EST 2015
Liposomal Glutathione Supplementation Restores TH1 Cytokine Response to Mycobacterium tuberculosis Infection in HIV-Infected Individuals.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Ly J,Lagman M,Saing T,Singh MK,Tudela EV,Morris D,Anderson J,Daliva J,Ochoa C,Patel N,Pearce D,Venketaraman V
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2015
Fractalkine receptor chemokine (CX3CR1) influences on cervical and lumbar disc herniation.
Indian journal of orthopaedics
Oh IS,Suh DW,Park SR,Ha KY
11-0049 was used in Flow cytometry/Cell sorting to clarify the role of CX3CL1 and CX3CR1 in spinal herniated nucleus pulposus.
Wed May 27 00:00:00 EDT 2015
Distinct patterns of intratumoral immune cell infiltrates in patients with HPV-associated compared to non-virally induced head and neck squamous cell carcinoma.
Oncoimmunology
Partlová S,Bouček J,Kloudová K,Lukešová E,Zábrodský M,Grega M,Fučíková J,Truxová I,Tachezy R,Špíšek R,Fialová A
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.
Nature communications
Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Tue Sep 15 00:00:00 EDT 2015
Investigating the causes for decreased levels of glutathione in individuals with type II diabetes.
PloS one
Lagman M,Ly J,Saing T,Kaur Singh M,Vera Tudela E,Morris D,Chi PT,Ochoa C,Sathananthan A,Venketaraman V
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Wed Dec 30 00:00:00 EST 2015
Severe impairment of regulatory T-cells and Th1-lymphocyte polarization in patients with Gaucher disease.
JIMD reports
Sotiropoulos C,Theodorou G,Repa C,Marinakis T,Verigou E,Solomou E,Karakantza M,Symeonidis A
11-0049 was used in Flow cytometry/Cell sorting to investigate peripheral blood T-lymphocyte subpopulations and intracellular expression of various interleukins and interferons in type I Gaucher disease patients.
Tue Mar 17 00:00:00 EDT 2015
A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3.
Oncoimmunology
Greenfield WW,Stratton SL,Myrick RS,Vaughn R,Donnalley LM,Coleman HN,Mercado M,Moerman-Herzog AM,Spencer HJ,Andrews-Collins NR,Hitt WC,Low GM,Manning NA,McKelvey SS,Smith D,Smith MV,Phillips AM,Quick CM,Jeffus SK,Hutchins LF,Nakagawa M
11-0049 was used in Flow cytometry/Cell sorting to demonstrate the safety of a human papillomavirus therapeutic vaccine, PepCan.
Thu Oct 01 00:00:00 EDT 2015
Immune response to JC virus T antigen in patients with and without colorectal neoplasia.
Gut microbes
Butcher LD,Garcia M,Arnold M,Ueno H,Goel A,Boland CR
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Tue Jul 01 00:00:00 EDT 2014
The disturbance of TH17-Treg cell balance in adenomyosis.
Fertility and sterility
Gui T,Chen C,Zhang Z,Tang W,Qian R,Ma X,Cao P,Wan G
11-0049 was used in Flow cytometry/Cell sorting to investigate the balance between Treg and T(H)17 cells in peripheral blood and uteri of women with adenomyosis.
Sat Feb 01 00:00:00 EST 2014
Hypomethylation at the regulatory T cell-specific demethylated region in CD25hi T cells is decoupled from FOXP3 expression at the inflamed site in childhood arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Bending D,Pesenacker AM,Ursu S,Wu Q,Lom H,Thirugnanabalan B,Wedderburn LR
11-0049 was used in Flow cytometry/Cell sorting to study dissociation of CD25 and FOXP3 in CD4+ T cells at the site of inflammation in patients with juvenile arthritis..
Mon Sep 15 00:00:00 EDT 2014
OMIP-022: Comprehensive assessment of antigen-specific human T-cell functionality and memory.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Graves AJ,Padilla MG,Hokey DA
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Tue Jul 01 00:00:00 EDT 2014
NOD-Rag2null IL-2Rγnull mice: an alternative to NOG mice for generation of humanized mice.
Experimental animals
Katano I,Ito R,Kamisako T,Eto T,Ogura T,Kawai K,Suemizu H,Takahashi T,Kawakami Y,Ito M
11-0049 was used in Flow cytometry/Cell sorting to evaluate the usefulness of NR2G mice as humanised mice by comparing human cell engraftment and differentiation among NOG, NR2G, and NOD-scid mice after HSC transplantation.
Mon Feb 09 00:00:00 EST 2015
Fully human antagonistic antibodies against CCR4 potently inhibit cell signaling and chemotaxis.
PloS one
Hagemann UB,Gunnarsson L,Géraudie S,Scheffler U,Griep RA,Reiersen H,Duncan AR,Kiprijanov SM
11-0049 was used in Flow cytometry/Cell sorting to demonstrate a significant survival benefit for animals treated with newly selected anti-CCR4 antibodies.
Fri Nov 13 00:00:00 EST 2015
Autologous Graft versus Host Disease: An Emerging Complication in Patients with Multiple Myeloma.
Bone marrow research
Batra A,Cottler-Fox M,Harville T,Rhodes-Clark BS,Makhoul I,Nakagawa M
11-0049 was used in Flow cytometry/Cell sorting to compare expression of cell surface molecules on hematopoietic progenitor cell products between healthy individuals and sufferers of autologous graft versus host disease.
Fri May 30 00:00:00 EDT 2014
ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death.
Autophagy
Garg AD,Dudek AM,Ferreira GB,Verfaillie T,Vandenabeele P,Krysko DV,Mathieu C,Agostinis P
11-0049 was used in Flow cytometry/Cell sorting to unravel a role for ROS-induced autophagy in weakening functional interaction between dying cancer cells and the immune system.
Sun Sep 01 00:00:00 EDT 2013
Human regulatory T cells kill tumor cells through granzyme-dependent cytotoxicity upon retargeting with a bispecific antibody.
Cancer immunology research
Choi BD,Gedeon PC,Herndon JE,Archer GE,Reap EA,Sanchez-Perez L,Mitchell DA,Bigner DD,Sampson JH
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Sun Sep 01 00:00:00 EDT 2013
Ribavirin Does Not Impair the Suppressive Activity of Foxp3(+)CD4(+)CD25(+) Regulatory T Cells.
Immune network
Lee J,Choi YS,Shin EC
11-0049 was used in Flow cytometry/Cell sorting to demonstrate that ribavirin did not attenuate the suppressive activity of Foxp3(+)CD4(+)CD25(+) Treg cells.
Fri Feb 01 00:00:00 EST 2013
High CCR6/CCR7 expression and Foxp3+ Treg cell number are positively related to the progression of laryngeal squamous cell carcinoma.
Oncology reports
Chen B,Zhang D,Zhou J,Li Q,Zhou L,Li SM,Zhu L,Chou KY,Zhou L,Tao L,Lu LM
11-0049 was used in Flow cytometry/Cell sorting to evaluate the expression and clinical significance of CCR6, CCR7, their ligands and CD4+CD25+Foxp3+ regulatory T cells in LSCC and LNs.
Sun Sep 01 00:00:00 EDT 2013
Programmed death-1+ T cells and regulatory T cells are enriched in tumor-involved lymph nodes and associated with aggressive features in papillary thyroid cancer.
The Journal of clinical endocrinology and metabolism
French JD,Kotnis GR,Said S,Raeburn CD,McIntyre RC,Klopper JP,Haugen BR
11-0049 was used in Flow cytometry/Cell sorting to characterise the CD4(+) T cell response to metastatic PTC.
Fri Jun 01 00:00:00 EDT 2012
Antigen-specific IL-2 secretion correlates with NK cell responses after immunization of Tanzanian children with the RTS,S/AS01 malaria vaccine.
Journal of immunology (Baltimore, Md. : 1950)
Horowitz A,Hafalla JC,King E,Lusingu J,Dekker D,Leach A,Moris P,Cohen J,Vekemans J,Villafana T,Corran PH,Bejon P,Drakeley CJ,von Seidlein L,Riley EM
11-0049 was used in Flow cytometry/Cell sorting to analyse immune cell responses to RTS,S and P. falciparum circumsporozoite protein component antigens in Tanzanian children.
Tue May 15 00:00:00 EDT 2012
Increased frequencies of Th22 cells as well as Th17 cells in the peripheral blood of patients with ankylosing spondylitis and rheumatoid arthritis.
PloS one
Zhang L,Li YG,Li YH,Qi L,Liu XG,Yuan CZ,Hu NW,Ma DX,Li ZF,Yang Q,Li W,Li JM
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Fri Jul 27 00:00:00 EDT 2012
Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients.
Critical care (London, England)
Zhang Y,Li J,Lou J,Zhou Y,Bo L,Zhu J,Zhu K,Wan X,Cai Z,Deng X
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Wed Dec 07 00:00:00 EST 2011
Anticardiac myosin immunity and chronic allograft vasculopathy in heart transplant recipients.
Journal of immunology (Baltimore, Md. : 1950)
Kalache S,Dinavahi R,Pinney S,Mehrotra A,Cunningham MW,Heeger PS
11-0049 was used in Flow cytometry/Cell sorting to investigate the pathogenesis of chronic allograft vasculopathy in heart transplant failure.
Fri Jul 15 00:00:00 EDT 2011
Modulation of CD4+ T lymphocyte lineage outcomes with targeted, nanoparticle-mediated cytokine delivery.
Molecular pharmaceutics
Park J,Gao W,Whiston R,Strom TB,Metcalfe S,Fahmy TM
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Mon Feb 07 00:00:00 EST 2011
Lymphotoxin signals from positively selected thymocytes regulate the terminal differentiation of medullary thymic epithelial cells.
Journal of immunology (Baltimore, Md. : 1950)
White AJ,Nakamura K,Jenkinson WE,Saini M,Sinclair C,Seddon B,Narendran P,Pfeffer K,Nitta T,Takahama Y,Caamano JH,Lane PJ,Jenkinson EJ,Anderson G
11-0049 was used in Immunofluorescence to explore the mechanisms behind Aire(+) medullary thymic epithelial cell development.
Fri Oct 15 00:00:00 EDT 2010
Sepsis-induced human lymphocyte apoptosis and cytokine production in "humanized" mice.
Journal of leukocyte biology
Unsinger J,McDonough JS,Shultz LD,Ferguson TA,Hotchkiss RS
11-0049 was used in Flow cytometry/Cell sorting to study sepsis-induced human lymphocyte apoptosis and cytokine production in "humanized" mice.
Sat Aug 01 00:00:00 EDT 2009
B cells and monocytes from patients with active multiple sclerosis exhibit increased surface expression of both HERV-H Env and HERV-W Env, accompanied by increased seroreactivity.
Retrovirology
Brudek T,Christensen T,Aagaard L,Petersen T,Hansen HJ,Møller-Larsen A
Published figure using CD4 monoclonal antibody (Product # 11-0049-80) in Flow Cytometry
Mon Nov 16 00:00:00 EST 2009
Expression and function of PDCD1 at the human maternal-fetal interface.
Biology of reproduction
Taglauer ES,Trikhacheva AS,Slusser JG,Petroff MG
11-0049 was used in Flow cytometry/Cell sorting to examine whether human maternal T cells express PDCD1.
Mon Sep 01 00:00:00 EDT 2008
Shared MHC class II-dependent melanoma ribosomal protein L8 identified by phage display.
Cancer research
Swoboda RK,Somasundaram R,Caputo L,Ochoa EM,Gimotty PA,Marincola FM,Van Belle P,Barth S,Elder D,Guerry D,Czerniecki B,Schuchter L,Vonderheide RH,Herlyn D
11-0049 was used in Flow cytometry/Cell sorting to investigate an antigen shared by melanoma and glioma cells that is recognised by T helper cells.
Sun Apr 15 00:00:00 EDT 2007
Functional inactivation of EBV-specific T-lymphocytes in nasopharyngeal carcinoma: implications for tumor immunotherapy.
PloS one
Li J,Zeng XH,Mo HY,Rolén U,Gao YF,Zhang XS,Chen QY,Zhang L,Zeng MS,Li MZ,Huang WL,Wang XN,Zeng YX,Masucci MG
11-0049 was used in Flow cytometry/Cell sorting to assess whether defects of EBV-specific immunity may contribute to tumoural growth.
Wed Nov 07 00:00:00 EST 2007
