Product References
Extracellular Galectin 4 Drives Immune Evasion and Promotes T-cell Apoptosis in Pancreatic Cancer.
Cancer immunology research
Lidström T,Cumming J,Gaur R,Frängsmyr L,Pateras IS,Mickert MJ,Franklin O,Forsell MNE,Arnberg N,Dongre M,Patthey C,Öhlund D
11-0451-82 was used in Flow cytometry/Cell sorting to show that gal 4 is involved in immune evasion and identify galectin 4 as a promising drug target for overcoming immunosuppression in PDAC.
Tue Jan 03 00:00:00 EST 2023
Extracellular Galectin 4 Drives Immune Evasion and Promotes T-cell Apoptosis in Pancreatic Cancer.
Cancer immunology research
Lidström T,Cumming J,Gaur R,Frängsmyr L,Pateras IS,Mickert MJ,Franklin O,Forsell MNE,Arnberg N,Dongre M,Patthey C,Öhlund D
11-0451-82 was used in Flow cytometry/Cell sorting to show that gal 4 is involved in immune evasion and identify galectin 4 as a promising drug target for overcoming immunosuppression in PDAC.
Tue Jan 03 00:00:00 EST 2023
Spleen-targeted neoantigen DNA vaccine for personalized immunotherapy of hepatocellular carcinoma.
EMBO molecular medicine
Wu M,Luo Z,Cai Z,Mao Q,Li Z,Li H,Zhang C,Zhang Y,Zhong A,Wu L,Liu X
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Oct 11 00:00:00 EDT 2023
GSDMD in peripheral myeloid cells regulates microglial immune training and neuroinflammation in Parkinson's disease.
Acta pharmaceutica Sinica. B
Wang B,Ma Y,Li S,Yao H,Gu M,Liu Y,Xue Y,Ding J,Ma C,Yang S,Hu G
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2023
Fibroblastic reticular cells in lymph node potentiate white adipose tissue beiging through neuro-immune crosstalk in male mice.
Nature communications
Cheong LY,Wang B,Wang Q,Jin L,Kwok KHM,Wu X,Shu L,Lin H,Chung SK,Cheng KKY,Hoo RLC,Xu A
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Mar 03 00:00:00 EST 2023
Macrophagic AMPKα1 orchestrates regenerative inflammation induced by glucocorticoids.
EMBO reports
Caratti G,Desgeorges T,Juban G,Stifel U,Fessard A,Koenen M,Caratti B,Théret M,Skurk C,Chazaud B,Tuckermann JP,Mounier R
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Feb 06 00:00:00 EST 2023
Topical Diacerein Decreases Skin and Splenic CD11c+ Dendritic Cells in Psoriasis.
International journal of molecular sciences
Brunner SM,Ramspacher A,Rieser C,Leitner J,Heil H,Ablinger M,Tevini J,Wimmer M,Koller A,Piñón Hofbauer J,Felder TK,Bauer JW,Kofler B,Lang R,Wally V
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Feb 21 00:00:00 EST 2023
Toll-like Receptor Signaling-deficient Cells Enhance Antitumor Activity of Cell-based Immunotherapy by Increasing Tumor Homing.
Cancer research communications
Morales-Molina A,Rodriguez-Milla MÁ,Gambera S,Cejalvo T,de Andrés B,Gaspar ML,García-Castro J
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Wed Mar 01 00:00:00 EST 2023
NAMPT encapsulated by extracellular vesicles from young adipose-derived mesenchymal stem cells treated tendinopathy in a "One-Stone-Two-Birds" manner.
Journal of nanobiotechnology
Wu G,Su Q,Li J,Xue C,Zhu J,Cai Q,Huang J,Ji S,Cheng B,Ge H
11-0451-82 was used in Flow cytometry/Cell sorting to demonstrate an effective novel therapy for tendinopathy and uncovers the influence of donor age on curative effects by clarifying the detailed biological mechanism.
Thu Jan 05 00:00:00 EST 2023
BRCA1 deficiency in mature CD8+ T lymphocytes impairs antitumor immunity.
Journal for immunotherapy of cancer
Wu B,Qi L,Chiang HC,Pan H,Zhang X,Greenbaum A,Stark E,Wang LJ,Chen Y,Haddad BR,Clagett D,Isaacs C,Elledge R,Horvath A,Hu Y,Li R
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2023
BRCA1 deficiency in mature CD8+ T lymphocytes impairs antitumor immunity.
Journal for immunotherapy of cancer
Wu B,Qi L,Chiang HC,Pan H,Zhang X,Greenbaum A,Stark E,Wang LJ,Chen Y,Haddad BR,Clagett D,Isaacs C,Elledge R,Horvath A,Hu Y,Li R
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2023
Bile salt hydrolase in non-enterotoxigenic Bacteroides potentiates colorectal cancer.
Nature communications
Sun L,Zhang Y,Cai J,Rimal B,Rocha ER,Coleman JP,Zhang C,Nichols RG,Luo Y,Kim B,Chen Y,Krausz KW,Harris CC,Patterson AD,Zhang Z,Takahashi S,Gonzalez FJ
11-0451-82 was used in Flow cytometry/Cell sorting to provide insights into the pro-carcinogenetic role of Bacteroides in obesity-related CRC progression and characterize Bile salt hydrolase (BSH) as a potential target for CRC prevention and treatment.
Fri Feb 10 00:00:00 EST 2023
CD11c+ microglia promote white matter repair after ischemic stroke.
Cell death & disease
Jia J,Zheng L,Ye L,Chen J,Shu S,Xu S,Bao X,Xia S,Liu R,Xu Y,Zhang M
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Feb 24 00:00:00 EST 2023
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
The expression of anti-aging protein Klotho is increased during neural differentiation of bone marrow-derived mesenchymal stem cells.
Cell biochemistry and function
Naeeni B,Taha MF,Emami Aleagha MS,Allameh A
11-0451-82 was used in Flow cytometry/Cell sorting to provide insight into the importance of Klotho protein in stem cell differentiation and regeneration in response to cell death in the central nervous system.
Wed Mar 01 00:00:00 EST 2023
Adipocyte-Secreted IL-6 Sensitizes Macrophages to IL-4 Signaling.
Diabetes
Luan D,Dadpey B,Zaid J,Bridge-Comer PE,DeLuca JH,Xia W,Castle J,Reilly SM
11-0451-82 was used in Flow Cytometry to investigate catabolic stimulation of adipocyte IL-6 secretion and its impact on adipose tissue immune cells.
Wed Mar 01 00:00:00 EST 2023
Senolytic elimination of Cox2-expressing senescent cells inhibits the growth of premalignant pancreatic lesions.
Gut
Kolodkin-Gal D,Roitman L,Ovadya Y,Azazmeh N,Assouline B,Schlesinger Y,Kalifa R,Horwitz S,Khalatnik Y,Hochner-Ger A,Imam A,Demma JA,Winter E,Benyamini H,Elgavish S,Khatib AA,Meir K,Atlan K,Pikarsky E,Parnas O,Dor Y,Zamir G,Ben-Porath I,Krizhanovsky V
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Tue Feb 01 00:00:00 EST 2022
The ZIP8/SIRT1 axis regulates alveolar progenitor cell renewal in aging and idiopathic pulmonary fibrosis.
The Journal of clinical investigation
Liang J,Huang G,Liu X,Taghavifar F,Liu N,Wang Y,Deng N,Yao C,Xie T,Kulur V,Dai K,Burman A,Rowan SC,Weigt SS,Belperio J,Stripp B,Parks WC,Jiang D,Noble PW
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2022
Interleukin-10 genetically modified clinical-grade mesenchymal stromal cells markedly reinforced functional recovery after spinal cord injury via directing alternative activation of macrophages.
Cellular & molecular biology letters
Gao T,Huang F,Wang W,Xie Y,Wang B
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Mar 17 00:00:00 EDT 2022
Interleukin-10 genetically modified clinical-grade mesenchymal stromal cells markedly reinforced functional recovery after spinal cord injury via directing alternative activation of macrophages.
Cellular & molecular biology letters
Gao T,Huang F,Wang W,Xie Y,Wang B
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Mar 17 00:00:00 EDT 2022
BEX1 is a critical determinant of viral myocarditis.
PLoS pathogens
Martens CR,Dorn LE,Kenney AD,Bansal SS,Yount JS,Accornero F
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Feb 01 00:00:00 EST 2022
miR-4759 suppresses breast cancer through immune checkpoint blockade.
Computational and structural biotechnology journal
Lin YZ,Liu SH,Wu WR,Shen YC,Wang YL,Liao CC,Lin PL,Chang H,Liu LC,Cheng WC,Wang SC
11-0451-82 was used in Flow Cytometry to demonstrate miR-4759 as a novel non-coding RNA which promotes anti-tumor immunity of breast cancer.
Sat Jan 15 00:00:00 EST 2022
GPR92 activation in islet macrophages controls β cell function in a diet-induced obesity model.
The Journal of clinical investigation
de Souza CO,Paschoal VA,Sun X,Vishvanath L,Zhang Q,Shao M,Onodera T,Chen S,Joffin N,Bueno LM,Gupta RK,Oh DY
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2022
GPR92 activation in islet macrophages controls β cell function in a diet-induced obesity model.
The Journal of clinical investigation
de Souza CO,Paschoal VA,Sun X,Vishvanath L,Zhang Q,Shao M,Onodera T,Chen S,Joffin N,Bueno LM,Gupta RK,Oh DY
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2022
Mineralocorticoid receptor antagonists and glucocorticoids differentially affect skeletal muscle inflammation and pathology in muscular dystrophy.
JCI insight
Howard ZM,Gomatam CK,Rabolli CP,Lowe J,Piepho AB,Bansal SS,Accornero F,Rafael-Fortney JA
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Oct 10 00:00:00 EDT 2022
Comparative analysis of thoracic and abdominal aortic aneurysms across the segment and species at the single-cell level.
Frontiers in pharmacology
Wu H,Xie C,Wang R,Cheng J,Xu Q,Zhao H
11-0451-82 was used in Flow cytometry/Cell sorting to suggest different biological functions and distinct potential pathogenic genes for thoracic and abdominal aortic aneurysms.
Thu Feb 02 00:00:00 EST 2023
Comparative analysis of thoracic and abdominal aortic aneurysms across the segment and species at the single-cell level.
Frontiers in pharmacology
Wu H,Xie C,Wang R,Cheng J,Xu Q,Zhao H
11-0451-82 was used in Flow cytometry/Cell sorting to suggest different biological functions and distinct potential pathogenic genes for thoracic and abdominal aortic aneurysms.
Thu Feb 02 00:00:00 EST 2023
Microglial angiotensin type 2 receptors mediate sex-specific expression of inflammatory cytokines independently of circulating estrogen.
Glia
Garrido-Gil P,Pedrosa MA,Garcia-Garrote M,Pequeño-Valtierra A,Rodríguez-Castro J,García-Souto D,Rodríguez-Pérez AI,Labandeira-Garcia JL
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
Hematopoietic-Mesenchymal Signals Regulate the Properties of Mesenchymal Stem Cells.
International journal of molecular sciences
Kanazawa S,Okada H,Riu D,Mabuchi Y,Akazawa C,Iwata J,Hoshi K,Hikita A
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Jul 26 00:00:00 EDT 2022
Gene-selective transcription promotes the inhibition of tissue reparative macrophages by TNF.
Life science alliance
Dichtl S,Sanin DE,Koss CK,Willenborg S,Petzold A,Tanzer MC,Dahl A,Kabat AM,Lindenthal L,Zeitler L,Satzinger S,Strasser A,Mann M,Roers A,Eming SA,El Kasmi KC,Pearce EJ,Murray PJ
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2022
Intranasal delivery of a small-molecule ErbB inhibitor promotes recovery from acute and late-stage CNS inflammation.
JCI insight
Linnerbauer M,Lößlein L,Vandrey O,Tsaktanis T,Beer A,Naumann UJ,Panier F,Beyer T,Nirschl L,Kuramatsu JB,Winkler J,Quintana FJ,Rothhammer V
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Apr 08 00:00:00 EDT 2022
A single-cell atlas reveals the heterogeneity of meningeal immunity in a mouse model of Methyl CpG binding protein 2 deficiency.
Frontiers in immunology
Li H,Hu M,Huang Z,Wang Y,Xu Y,Deng J,Zhu M,Feng W,Xu X
11-0451-82 was used in Flow cytometry/Cell sorting to provide novel insights into meningeal immunity, which is a less studied aspect of neuroimmune interactions in Mecp2-mutated diseases, and offer an essential resource for comparative analyses and data exploration to better understand the functional role of meningeal immunity in RTT.
Tue Jan 31 00:00:00 EST 2023
Meningeal lymphatic drainage promotes T cell responses against Toxoplasma gondii but is dispensable for parasite control in the brain.
eLife
Kovacs MA,Cowan MN,Babcock IW,Sibley LA,Still K,Batista SJ,Labuzan SA,Sethi I,Harris TH
11-0451-82 was used in Flow cytometry/Cell sorting to reveal that CNS lymphatic drainage supports the development of peripheral T cell responses against T. gondii but remains dispensable for immune protection of the brain.
Wed Dec 21 00:00:00 EST 2022
Trappc9 Deficiency Impairs the Plasticity of Stem Cells.
International journal of molecular sciences
Usman M,Li Y,Ke Y,Chhetri G,Islam MA,Wang Z,Li X
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunocytochemistry
Thu Apr 28 00:00:00 EDT 2022
CD4+ CTLs Act as a Key Effector Population for Allograft Rejection of MSCs in a Donor MHC-II Dependent Manner in Injured Liver.
Aging and disease
Shen S,Li Y,Jin M,Fan D,Pan R,Lin A,Chen Y,Xiang L,Zhao RC,Shao J
11-0451-82 was used in Flow cytometry/Cell sorting to reveal a novel mechanism of MSC allograft rejection mediated by CD4+ CTLs in injured liver, which provided new strategies for improving clinical performance of allo-MSCs in benefiting hepatic injury repair.
Thu Dec 01 00:00:00 EST 2022
IRE1α drives lung epithelial progenitor dysfunction to establish a niche for pulmonary fibrosis.
American journal of physiology. Lung cellular and molecular physiology
Auyeung VC,Downey MS,Thamsen M,Wenger TA,Backes BJ,Sheppard D,Papa FR
11-0451-82 was used in Flow cytometry/Cell sorting to show that the bifunctional kinase/RNase-IRE1α-a central mediator of the unfolded protein response (UPR) to endoplasmic reticulum (ER) stress is a critical promoter of DATP abundance and function.
Fri Apr 01 00:00:00 EDT 2022
TNF hampers intestinal tissue repair in colitis by restricting IL-22 bioavailability.
Mucosal immunology
Ninnemann J,Winsauer C,Bondareva M,Kühl AA,Lozza L,Durek P,Lissner D,Siegmund B,Kaufmann SHE,Mashreghi MF,Nedospasov SA,Kruglov AA
11-0451-82 was used in Flow cytometry/Cell sorting to show how anti-TNF therapy induces mucosal healing by increasing IL-22 availability and implicates new therapeutic opportunities for IBD.
Fri Apr 01 00:00:00 EDT 2022
Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity.
Science advances
Kumar B,Adebayo AK,Prasad M,Capitano ML,Wang R,Bhat-Nakshatri P,Anjanappa M,Simpson E,Chen D,Liu Y,Schilder JM,Colter AB,Maguire C,Temm CJ,Sandusky G,Doud EH,Wijeratne AB,Mosley AL,Broxmeyer HE,Nakshatri H
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Jan 14 00:00:00 EST 2022
The RNA-binding protein IMP2 drives a stromal-Th17 cell circuit in autoimmune neuroinflammation.
JCI insight
Bechara R,Amatya N,Majumder S,Zhou C,Li Y,Liu Q,McGeachy MJ,Gaffen SL
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Feb 08 00:00:00 EST 2022
A Point Mutation R122C in RUNX3 Promotes the Expansion of Isthmus Stem Cells and Inhibits Their Differentiation in the Stomach.
Cellular and molecular gastroenterology and hepatology
Douchi D,Yamamura A,Matsuo J,Lee JW,Nuttonmanit N,Melissa Lim YH,Suda K,Shimura M,Chen S,Pang S,Kohu K,Kaneko M,Kiyonari H,Kaneda A,Yoshida H,Taniuchi I,Osato M,Yang H,Unno M,Bok-Yan So J,Yeoh KG,Chuang LSH,Bae SC,Ito Y
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Mon Apr 18 00:00:00 EDT 2022
Maternal inappropriate calcium intake aggravates dietary-induced obesity in male offspring by affecting the differentiation potential of mesenchymal stem cells.
World journal of stem cells
Li P,Wang Y,Li P,Liu YL,Liu WJ,Chen XY,Tang TT,Qi KM,Zhang Y
11-0451-82 was used in Flow cytometry/Cell sorting to show that early-life abnormal dietary calcium intake might program the adipogenic differentiation potential of BMSCs from male offspring, with significant expressions on the Wnt/β-catenin signaling pathway to aggravate high-fat-diet-induced obesity in adulthood.
Wed Oct 26 00:00:00 EDT 2022
Ccrl2 deficiency deteriorates obesity and insulin resistance through increasing adipose tissue macrophages infiltration.
Genes & diseases
Xu M,Wang YM,Li WQ,Huang CL,Li J,Xie WH,Zeng HX,Tao LF,Li X
11-0451-82 was used in Flow cytometry/Cell sorting to indicate that Ccrl2 has a critical function in obesity and obesity-induced insulin resistance via mediating macrophages chemotaxis.
Tue Mar 01 00:00:00 EST 2022
Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19.
Cell host & microbe
Guo Q,Zhao Y,Li J,Liu J,Yang X,Guo X,Kuang M,Xia H,Zhang Z,Cao L,Luo Y,Bao L,Wang X,Wei X,Deng W,Wang N,Chen L,Chen J,Zhu H,Gao R,Qin C,Wang X,You F
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Feb 10 00:00:00 EST 2021
Stage-specific action of Runx1 and GATA3 controls silencing of PU.1 expression in mouse pro-T cells.
The Journal of experimental medicine
Hosokawa H,Koizumi M,Masuhara K,Romero-Wolf M,Tanaka T,Nakayama T,Rothenberg EV
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
AIM2 controls microglial inflammation to prevent experimental autoimmune encephalomyelitis.
The Journal of experimental medicine
Ma C,Li S,Hu Y,Ma Y,Wu Y,Wu C,Liu X,Wang B,Hu G,Zhou J,Yang S
11-0451 was used in Flow cytometry/Cell sorting to identify a new role for AIM2 in controlling the onset of EAE.
Mon May 03 00:00:00 EDT 2021
Uptake and trafficking of different sized PLGA nanoparticles by dendritic cells in imiquimod-induced psoriasis-like mice model.
Acta pharmaceutica Sinica. B
Lin Z,Xi L,Chen S,Tao J,Wang Y,Chen X,Li P,Wang Z,Zheng Y
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Mapping the origin and fate of myeloid cells in distinct compartments of the eye by single-cell profiling.
The EMBO journal
Wieghofer P,Hagemeyer N,Sankowski R,Schlecht A,Staszewski O,Amann L,Gruber M,Koch J,Hausmann A,Zhang P,Boneva S,Masuda T,Hilgendorf I,Goldmann T,Böttcher C,Priller J,Rossi FM,Lange C,Prinz M
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Mar 15 00:00:00 EDT 2021
Ablation of lysozyme M-positive cells prevents aircraft noise-induced vascular damage without improving cerebral side effects.
Basic research in cardiology
Frenis K,Helmstädter J,Ruan Y,Schramm E,Kalinovic S,Kröller-Schön S,Bayo Jimenez MT,Hahad O,Oelze M,Jiang S,Wenzel P,Sommer CJ,Frauenknecht KBM,Waisman A,Gericke A,Daiber A,Münzel T,Steven S
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Apr 30 00:00:00 EDT 2021
Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degeneration.
Cell death and differentiation
Deng CL,Hu CB,Ling ST,Zhao N,Bao LH,Zhou F,Xiong YC,Chen T,Sui BD,Yu XR,Hu CH
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2021
Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin.
Cell death and differentiation
Velletri T,Huang Y,Wang Y,Li Q,Hu M,Xie N,Yang Q,Chen X,Chen Q,Shou P,Gan Y,Candi E,Annicchiarico-Petruzzelli M,Agostini M,Yang H,Melino G,Shi Y,Wang Y
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Decreased antiviral immune response within the central nervous system of aged mice is associated with increased lethality of West Nile virus encephalitis.
Aging cell
Funk KE,Arutyunov AD,Desai P,White JP,Soung AL,Rosen SF,Diamond MS,Klein RS
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sun Aug 01 00:00:00 EDT 2021
Deletion of mTOR in liver epithelial cells enhances hepatic metastasis of colon cancer.
The Journal of pathology
Jiao L,Eickhoff R,Egners A,Jumpertz S,Roth J,Erdem M,Kroh A,Duimel H,López-Iglesias C,Caro P,Heij LR,Schmeding M,Meierhofer D,Neumann UP,Cramer T
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Mon Nov 01 00:00:00 EDT 2021
Anti-adipogenic signals at the onset of obesity-related inflammation in white adipose tissue.
Cellular and molecular life sciences : CMLS
Caputo T,Tran VDT,Bararpour N,Winkler C,Aguileta G,Trang KB,Giordano Attianese GMP,Wilson A,Thomas A,Pagni M,Guex N,Desvergne B,Gilardi F
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
RANKL from bone marrow adipose lineage cells promotes osteoclast formation and bone loss.
EMBO reports
Hu Y,Li X,Zhi X,Cong W,Huang B,Chen H,Wang Y,Li Y,Wang L,Fang C,Guo J,Liu Y,Cui J,Cao L,Weng W,Zhou Q,Wang S,Chen X,Su J
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Macrophage polarization by MSC-derived CXCL12 determines tumor growth.
Cellular & molecular biology letters
Babazadeh S,Nassiri SM,Siavashi V,Sahlabadi M,Hajinasrollah M,Zamani-Ahmadmahmudi M
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sat Jun 26 00:00:00 EDT 2021
The effects of postmortem delay on mouse and human microglia gene expression.
Glia
Heng Y,Dubbelaar ML,Marie SKN,Boddeke EWGM,Eggen BJL
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
The effects of postmortem delay on mouse and human microglia gene expression.
Glia
Heng Y,Dubbelaar ML,Marie SKN,Boddeke EWGM,Eggen BJL
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Intrinsic DNA damage repair deficiency results in progressive microglia loss and replacement.
Glia
Zhang X,Heng Y,Kooistra SM,van Weering HRJ,Brummer ML,Gerrits E,Wesseling EM,Brouwer N,Nijboer TW,Dubbelaar ML,Boddeke EWGM,Eggen BJL
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2021
Intrinsic DNA damage repair deficiency results in progressive microglia loss and replacement.
Glia
Zhang X,Heng Y,Kooistra SM,van Weering HRJ,Brummer ML,Gerrits E,Wesseling EM,Brouwer N,Nijboer TW,Dubbelaar ML,Boddeke EWGM,Eggen BJL
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2021
PD-L1 overexpression conveys tolerance of mesenchymal stem cell-derived cardiomyocyte-like cells in an allogeneic mouse model.
Journal of cellular physiology
Mardomi A,Limoni SK,Rahbarghazi R,Mohammadi N,Khorashadizadeh M,Ranjbaran H,Nataj HH,Jafari N,Hasani B,Abediankenari S
11-0451-82 was used in Flow Cytometry to verify the potential of PD-L1 overexpression as a preparative strategy for the protection of allogeneic MSCs-derived CLCs against the detrimental alloreaction.© 2021 Wiley Periodicals LLC.
Wed Sep 01 00:00:00 EDT 2021
Intercellular Interactions of an Adipogenic CXCL12-Expressing Stromal Cell Subset in Murine Bone Marrow.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Matsushita Y,Chu AKY,Ono W,Welch JD,Ono N
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunocytochemistry
Tue Jun 01 00:00:00 EDT 2021
Intercellular Interactions of an Adipogenic CXCL12-Expressing Stromal Cell Subset in Murine Bone Marrow.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Matsushita Y,Chu AKY,Ono W,Welch JD,Ono N
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunocytochemistry
Tue Jun 01 00:00:00 EDT 2021
Macrophage LAMTOR1 Deficiency Prevents Dietary Obesity and Insulin Resistance Through Inflammation-Induced Energy Expenditure.
Frontiers in cell and developmental biology
Ying L,Zhang M,Ma X,Si Y,Li X,Su J,Yin J,Bao Y
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Jun 08 00:00:00 EDT 2021
A novel Cytochrome P450 26A1 expressing NK cell subset at the mouse maternal-foetal interface.
Journal of cellular and molecular medicine
Wei DP,Li DD,Gu AQ,Ji WH,Yang Y,Peng JP
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunocytochemistry
Mon Feb 01 00:00:00 EST 2021
The laminin-binding integrins regulate nuclear factor κB-dependent epithelial cell polarity and inflammation.
Journal of cell science
Yazlovitskaya EM,Plosa E,Bock F,Viquez OM,Mernaugh G,Gewin LS,De Arcangelis A,Georges-Labouesse E,Sonnenberg A,Blackwell TS,Pozzi A,Zent R
11-0451-82 was used in Flow cytometry/Cell sorting to suggest that laminin-binding integrins play a key role in the maintenance of kidney tubule epithelial cell polarity and decrease pro-inflammatory cytokine secretion by regulating NF-κB-dependent signaling.
Wed Dec 15 00:00:00 EST 2021
Prevention of EAE by tolerogenic vaccination with PEGylated antigenic peptides.
Therapeutic advances in chronic disease
Pfeil J,Simonetti M,Lauer U,von Thülen B,Durek P,Poulsen C,Pawlowska J,Kröger M,Krähmer R,Leenders F,Hoffmann U,Hamann A
11-0451-82 was used in Flow Cytometry to investigate whether the tolerogenic potential of immunodominant myelin T-cell epitopes can be improved by conjugation to the synthetic carrier polyethylene glycol (PEG) in an experimental autoimmune encephalomyelitis (EAE) mouse model for chronic MS (MOG C57BL/6).
Tue Nov 07 00:00:00 EST 2023
Alterations of macrophage and neutrophil content in skeletal muscle of aged versus young mice.
Muscle & nerve
Kawanishi N,Machida S
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Differential activation of Ca2+ influx channels modulate stem cell potency, their proliferation/viability and tissue regeneration.
NPJ Regenerative medicine
Ahamad N,Sun Y,Nascimento Da Conceicao V,Xavier Paul Ezhilan CRD,Natarajan M,Singh BB
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Wed Oct 20 00:00:00 EDT 2021
Differential activation of Ca2+ influx channels modulate stem cell potency, their proliferation/viability and tissue regeneration.
NPJ Regenerative medicine
Ahamad N,Sun Y,Nascimento Da Conceicao V,Xavier Paul Ezhilan CRD,Natarajan M,Singh BB
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Wed Oct 20 00:00:00 EDT 2021
Differential activation of Ca2+ influx channels modulate stem cell potency, their proliferation/viability and tissue regeneration.
NPJ Regenerative medicine
Ahamad N,Sun Y,Nascimento Da Conceicao V,Xavier Paul Ezhilan CRD,Natarajan M,Singh BB
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Wed Oct 20 00:00:00 EDT 2021
Suppression of mucosal Th17 memory responses by acellular pertussis vaccines enhances nasal Bordetella pertussis carriage.
NPJ vaccines
Dubois V,Chatagnon J,Thiriard A,Bauderlique-Le Roy H,Debrie AS,Coutte L,Locht C
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Jan 08 00:00:00 EST 2021
Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40.
Nature communications
Yang F,He Z,Duan H,Zhang D,Li J,Yang H,Dorsey JF,Zou W,Nabavizadeh SA,Bagley SJ,Abdullah K,Brem S,Zhang L,Xu X,Byrne KT,Vonderheide RH,Gong Y,Fan Y
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Jun 08 00:00:00 EDT 2021
The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia.
Journal of neuroinflammation
Malone K,Diaz Diaz AC,Shearer JA,Moore AC,Waeber C
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sat Jan 30 00:00:00 EST 2021
NOX4 regulates macrophage apoptosis resistance to induce fibrotic progression.
The Journal of biological chemistry
Larson-Casey JL,Gu L,Kang J,Dhyani A,Carter AB
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Jul 01 00:00:00 EDT 2021
The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.
eLife
Roy A,Tomaz da Silva M,Bhat R,Bohnert KR,Iwawaki T,Kumar A
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Nov 23 00:00:00 EST 2021
A decrease in NAD+ contributes to the loss of osteoprogenitors and bone mass with aging.
NPJ aging and mechanisms of disease
Kim HN,Ponte F,Warren A,Ring R,Iyer S,Han L,Almeida M
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Therapeutic Potential of Mesenchymal Stem Cells in a Pre-Clinical Model of Diabetic Kidney Disease and Obesity.
International journal of molecular sciences
Sávio-Silva C,Soinski-Sousa PE,Simplício-Filho A,Bastos RMC,Beyerstedt S,Rangel ÉB
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Feb 04 00:00:00 EST 2021
Therapeutic Potential of Mesenchymal Stem Cells in a Pre-Clinical Model of Diabetic Kidney Disease and Obesity.
International journal of molecular sciences
Sávio-Silva C,Soinski-Sousa PE,Simplício-Filho A,Bastos RMC,Beyerstedt S,Rangel ÉB
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Feb 04 00:00:00 EST 2021
Use of a Self-Delivering Anti-CCL3 FANA Oligonucleotide as an Innovative Approach to Target Inflammation after Spinal Cord Injury.
eNeuro
Pelisch N,Rosas Almanza J,Stehlik KE,Aperi BV,Kroner A
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Jun 18 00:00:00 EDT 2021
T cell-depleting nanoparticles ameliorate bone loss by reducing activated T cells and regulating the Treg/Th17 balance.
Bioactive materials
Yang X,Zhou F,Yuan P,Dou G,Liu X,Liu S,Wang X,Jin R,Dong Y,Zhou J,Lv Y,Deng Z,Liu S,Chen X,Han Y,Jin Y
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2021
Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice.
eLife
Kuhn JA,Vainchtein ID,Braz J,Hamel K,Bernstein M,Craik V,Dahlgren MW,Ortiz-Carpena J,Molofsky AB,Molofsky AV,Basbaum AI
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Oct 15 00:00:00 EDT 2021
Placenta-Expanded Stromal Cell Therapy in a Rodent Model of Simulated Weightlessness.
Cells
Rubinstein L,Paul AM,Houseman C,Abegaz M,Tabares Ruiz S,O'Neil N,Kunis G,Ofir R,Cohen J,Ronca AE,Globus RK,Tahimic CGT
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Apr 19 00:00:00 EDT 2021
Placenta-Expanded Stromal Cell Therapy in a Rodent Model of Simulated Weightlessness.
Cells
Rubinstein L,Paul AM,Houseman C,Abegaz M,Tabares Ruiz S,O'Neil N,Kunis G,Ofir R,Cohen J,Ronca AE,Globus RK,Tahimic CGT
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Apr 19 00:00:00 EDT 2021
Apoptotic vesicles restore liver macrophage homeostasis to counteract type 2 diabetes.
Journal of extracellular vesicles
Zheng C,Sui B,Zhang X,Hu J,Chen J,Liu J,Wu D,Ye Q,Xiang L,Qiu X,Liu S,Deng Z,Zhou J,Liu S,Shi S,Jin Y
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Distinct skeletal stem cell types orchestrate long bone skeletogenesis.
eLife
Ambrosi TH,Sinha R,Steininger HM,Hoover MY,Murphy MP,Koepke LS,Wang Y,Lu WJ,Morri M,Neff NF,Weissman IL,Longaker MT,Chan CK
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Jul 19 00:00:00 EDT 2021
Distinct skeletal stem cell types orchestrate long bone skeletogenesis.
eLife
Ambrosi TH,Sinha R,Steininger HM,Hoover MY,Murphy MP,Koepke LS,Wang Y,Lu WJ,Morri M,Neff NF,Weissman IL,Longaker MT,Chan CK
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Jul 19 00:00:00 EDT 2021
Integrated OMICs unveil the bone-marrow microenvironment in human leukemia.
Cell reports
Passaro D,Garcia-Albornoz M,Diana G,Chakravarty P,Ariza-McNaughton L,Batsivari A,Borràs-Eroles C,Abarrategi A,Waclawiczek A,Ombrato L,Malanchi I,Gribben J,Bonnet D
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue May 11 00:00:00 EDT 2021
PTENα functions as an immune suppressor and promotes immune resistance in PTEN-mutant cancer.
Nature communications
Sun Y,Lu D,Yin Y,Song J,Liu Y,Hao W,Qi F,Zhang G,Zhang X,Liu L,Lin Z,Liang H,Zhao X,Jin Y,Yin Y
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Aug 26 00:00:00 EDT 2021
Cardiac-derived TGF-β1 confers resistance to diet-induced obesity through the regulation of adipocyte size and function.
Molecular metabolism
Longenecker JZ,Petrosino JM,Martens CR,Hinger SA,Royer CJ,Dorn LE,Branch DA,Serrano J,Stanford KI,Kyriazis GA,Baskin KK,Accornero F
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Dec 01 00:00:00 EST 2021
Determining the effect of aging, recovery time, and post-stroke memantine treatment on delayed thalamic gliosis after cortical infarct.
Scientific reports
Kim GS,Stephenson JM,Al Mamun A,Wu T,Goss MG,Min JW,Li J,Liu F,Marrelli SP
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Jun 15 00:00:00 EDT 2021
Cytochrome P450 26A1 Modulates the Polarization of Uterine Macrophages During the Peri-Implantation Period.
Frontiers in immunology
Ji WH,Li DD,Wei DP,Gu AQ,Yang Y,Peng JP
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Feb 10 00:00:00 EST 2022
Cytochrome P450 26A1 Modulates the Polarization of Uterine Macrophages During the Peri-Implantation Period.
Frontiers in immunology
Ji WH,Li DD,Wei DP,Gu AQ,Yang Y,Peng JP
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Feb 10 00:00:00 EST 2022
A molybdenum oxide-based degradable nanosheet for combined chemo-photothermal therapy to improve tumor immunosuppression and suppress distant tumors and lung metastases.
Journal of nanobiotechnology
Qiu N,Yang X,Zhang Y,Zhang J,Ji J,Zhang Y,Kong X,Xi Y,Liu D,Ye L,Zhai G
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sun Dec 19 00:00:00 EST 2021
Visceral adipose tissue imparts peripheral macrophage influx into the hypothalamus.
Journal of neuroinflammation
Chen KE,Lainez NM,Nair MG,Coss D
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Jun 21 00:00:00 EDT 2021
Quantitative in vivo assessment of amyloid-beta phagocytic capacity in an Alzheimer's disease mouse model.
STAR protocols
Lau SF,Wu W,Seo H,Fu AKY,Ip NY
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Mar 19 00:00:00 EDT 2021
Quantitative in vivo assessment of amyloid-beta phagocytic capacity in an Alzheimer's disease mouse model.
STAR protocols
Lau SF,Wu W,Seo H,Fu AKY,Ip NY
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Mar 19 00:00:00 EDT 2021
Wip1 regulates the immunomodulatory effects of murine mesenchymal stem cells in type 1 diabetes mellitus via targeting IFN-α/BST2.
Cell death discovery
Zhou N,Liu W,Zhang W,Liu Y,Li X,Wang Y,Zheng R,Zhang Y
11-0451-82 was used in Flow Cytometry to reveal Wip1 affects MSCs immunomodulation by regulating the expression of IFN-α/BST2.
Fri Oct 29 00:00:00 EDT 2021
Mice with induced pulmonary morbidities display severe lung inflammation and mortality following exposure to SARS-CoV-2.
JCI insight
Falach R,Bar-On L,Lazar S,Kadar T,Mazor O,Aftalion M,Gur D,Evgy Y,Shifman O,Aminov T,Israeli O,Cohen-Gihon I,Zaide G,Gutman H,Vagima Y,Makdasi E,Stein D,Rosenfeld R,Alcalay R,Zahavy E,Levy H,Glinert I,Ben-Shmuel A,Israely T,Melamed S,Politi B,Achdout H,Yitzhaki S,Kronman C,Sabo T
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Jun 22 00:00:00 EDT 2021
Mice with induced pulmonary morbidities display severe lung inflammation and mortality following exposure to SARS-CoV-2.
JCI insight
Falach R,Bar-On L,Lazar S,Kadar T,Mazor O,Aftalion M,Gur D,Evgy Y,Shifman O,Aminov T,Israeli O,Cohen-Gihon I,Zaide G,Gutman H,Vagima Y,Makdasi E,Stein D,Rosenfeld R,Alcalay R,Zahavy E,Levy H,Glinert I,Ben-Shmuel A,Israely T,Melamed S,Politi B,Achdout H,Yitzhaki S,Kronman C,Sabo T
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Jun 22 00:00:00 EDT 2021
Anti-PD-1 Checkpoint Therapy Can Promote the Function and Survival of Regulatory T Cells.
Journal of immunology (Baltimore, Md. : 1950)
Vick SC,Kolupaev OV,Perou CM,Serody JS
11-0451-82 was used in Flow cytometry/Cell sorting to show that this immunotherapy blockade increases proliferation, protection from apoptosis, and suppressive capabilities of Tregs, thus leading to enhanced immunosuppression in the TME.
Mon Nov 15 00:00:00 EST 2021
Modulation of lactate-lysosome axis in dendritic cells by clotrimazole potentiates antitumor immunity.
Journal for immunotherapy of cancer
Wang Z,Xu F,Hu J,Zhang H,Cui L,Lu W,He W,Wang X,Li M,Zhang H,Xiong W,Xie C,Liu Y,Zhou P,Liu J,Huang P,Qin XF,Xia X
11-0451-82 was used in Flow Cytometry to show that clotrimazole could trigger DC activation via the lactate-lysosome axis to promote antigen cross-presentation and could be used as a potential combination therapy approach to improving the therapeutic efficacy of anti-PD1 immunotherapy.
Sat May 01 00:00:00 EDT 2021
Cellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue.
Nature communications
Ribas-Latre A,Santos RB,Fekry B,Tamim YM,Shivshankar S,Mohamed AMT,Baumgartner C,Kwok C,Gebhardt C,Rivera A,Gao Z,Sun K,Heiker JT,Snyder BE,Kolonin MG,Eckel-Mahan KL
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunocytochemistry
Wed Jun 09 00:00:00 EDT 2021
Increased Levels of IL-16 in the Central Nervous System during Neuroinflammation Are Associated with Infiltrating Immune Cells and Resident Glial Cells.
Biology
Hridi SU,Barbour M,Wilson C,Franssen AJ,Harte T,Bushell TJ,Jiang HR
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry (Frozen)
Thu May 27 00:00:00 EDT 2021
IDO1 Expression in Ovarian Cancer Induces PD-1 in T Cells via Aryl Hydrocarbon Receptor Activation.
Frontiers in immunology
Amobi-McCloud A,Muthuswamy R,Battaglia S,Yu H,Liu T,Wang J,Putluri V,Singh PK,Qian F,Huang RY,Putluri N,Tsuji T,Lugade AA,Liu S,Odunsi K
11-0451-82 was used in Flow Cytometry to enable the design of strategies to target the IDO1 and AHR pathways for enhancing anti-tumor immunity in ovarian cancer.
Fri Oct 29 00:00:00 EDT 2021
Mesenchymal stem cell exosome-derived miR-223 alleviates acute graft-versus-host disease via reducing the migration of donor T cells.
Stem cell research & therapy
Liu W,Zhou N,Liu Y,Zhang W,Li X,Wang Y,Zheng R,Zhang Y
11-0451-82 was used in Flow cytometry/Cell sorting to unveil a new role of MSCs-Exo containing miR-223 in the treatment of acute graft-versus-host disease (aGvHD).
Fri Feb 26 00:00:00 EST 2021
Single-cell analyses unravel cell type-specific responses to a vitamin D analog in prostatic precancerous lesions.
Science advances
Abu El Maaty MA,Grelet E,Keime C,Rerra AI,Gantzer J,Emprou C,Terzic J,Lutzing R,Bornert JM,Laverny G,Metzger D
11-0451-82 was used in Flow Cytometry to determine the impact of vitamin D signaling on prostatic precancerous lesions.
Thu Jul 01 00:00:00 EDT 2021
VISTA regulates microglia homeostasis and myelin phagocytosis, and is associated with MS lesion pathology.
Acta neuropathologica communications
Borggrewe M,Kooistra SM,Wesseling EM,Gierschek FL,Brummer ML,Nowak EC,Medeiros-Furquim T,Otto TA,Lee SW,Noelle RJ,Eggen BJL,Laman JD
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Tue May 18 00:00:00 EDT 2021
The Absence of Extracellular Cold-Inducible RNA-Binding Protein (eCIRP) Promotes Pro-Angiogenic Microenvironmental Conditions and Angiogenesis in Muscle Tissue Ischemia.
International journal of molecular sciences
Kübler M,Beck S,Peffenköver LL,Götz P,Ishikawa-Ankerhold H,Preissner KT,Fischer S,Lasch M,Deindl E
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunocytochemistry
Tue Aug 31 00:00:00 EDT 2021
Increasing cytosolic Ca2+ levels restore cell proliferation and stem cell potency in aged MSCs.
Stem cell research
Ahamad N,Sun Y,Singh BB
11-0451-82 was used in Cell Culture to suggest that Ca2+ entry is essential for preventing the loss of aged stem cell function and supplementing Ca2+ not only restored their proliferative potential but, allowed them to develop into younger stem cell lineages that could be critical for regenerative medicine.
Fri Oct 01 00:00:00 EDT 2021
TOX Acts as a Tumor Suppressor by Inhibiting mTOR Signaling in Colorectal Cancer.
Frontiers in immunology
Yang M,Huang Q,Li C,Jiang Z,Sun J,Wang Z,Liang R,Li D,Li B,Zhao H
11-0451-82 was used in Flow Cytometry to highlight the tumor-suppressive role of TOX in CRC, especially in MSI CRC, and provide valuable information that rapamycin alone or combined with PD1 inhibitor has therapeutic potential in CRC.
Wed Oct 06 00:00:00 EDT 2021
C3 Deficiency Leads to Increased Angiogenesis and Elevated Pro-Angiogenic Leukocyte Recruitment in Ischemic Muscle Tissue.
International journal of molecular sciences
Götz P,Braumandl A,Kübler M,Kumaraswami K,Ishikawa-Ankerhold H,Lasch M,Deindl E
11-0451-82 was used in Immunohistochemistry (Frozen) to show that the deficiency of complement factor C3 increased neutrophil and M2-like polarized macrophage accumulation in ischemic muscle tissue, contributing to angiogenesis.
Fri May 28 00:00:00 EDT 2021
C3 Deficiency Leads to Increased Angiogenesis and Elevated Pro-Angiogenic Leukocyte Recruitment in Ischemic Muscle Tissue.
International journal of molecular sciences
Götz P,Braumandl A,Kübler M,Kumaraswami K,Ishikawa-Ankerhold H,Lasch M,Deindl E
11-0451-82 was used in Immunohistochemistry (Frozen) to show that the deficiency of complement factor C3 increased neutrophil and M2-like polarized macrophage accumulation in ischemic muscle tissue, contributing to angiogenesis.
Fri May 28 00:00:00 EDT 2021
C3 Deficiency Leads to Increased Angiogenesis and Elevated Pro-Angiogenic Leukocyte Recruitment in Ischemic Muscle Tissue.
International journal of molecular sciences
Götz P,Braumandl A,Kübler M,Kumaraswami K,Ishikawa-Ankerhold H,Lasch M,Deindl E
11-0451-82 was used in Immunohistochemistry (Frozen) to show that the deficiency of complement factor C3 increased neutrophil and M2-like polarized macrophage accumulation in ischemic muscle tissue, contributing to angiogenesis.
Fri May 28 00:00:00 EDT 2021
Absence of Cold-Inducible RNA-Binding Protein (CIRP) Promotes Angiogenesis and Regeneration of Ischemic Tissue by Inducing M2-Like Macrophage Polarization.
Biomedicines
Kübler M,Beck S,Fischer S,Götz P,Kumaraswami K,Ishikawa-Ankerhold H,Lasch M,Deindl E
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Wed Apr 07 00:00:00 EDT 2021
Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis.
Frontiers in immunology
Yang P,Tian H,Zou YR,Chambon P,Ichinose H,Honig G,Diamond B,Kim SJ
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury.
Nature communications
Jin H,Liu K,Tang J,Huang X,Wang H,Zhang Q,Zhu H,Li Y,Pu W,Zhao H,He L,Li Y,Zhang S,Zhang Z,Zhao Y,Qin Y,Pflanz S,Kasmi KEI,Zhang W,Liu Z,Ginhoux F,Ji Y,He B,Wang L,Zhou B
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry (PFA fixed)
Mon May 17 00:00:00 EDT 2021
Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury.
Nature communications
Jin H,Liu K,Tang J,Huang X,Wang H,Zhang Q,Zhu H,Li Y,Pu W,Zhao H,He L,Li Y,Zhang S,Zhang Z,Zhao Y,Qin Y,Pflanz S,Kasmi KEI,Zhang W,Liu Z,Ginhoux F,Ji Y,He B,Wang L,Zhou B
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry (PFA fixed)
Mon May 17 00:00:00 EDT 2021
Systemic administration of β-glucan induces immune training in microglia.
Journal of neuroinflammation
Heng Y,Zhang X,Borggrewe M,van Weering HRJ,Brummer ML,Nijboer TW,Joosten LAB,Netea MG,Boddeke EWGM,Laman JD,Eggen BJL
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Feb 22 00:00:00 EST 2021
Systemic administration of β-glucan induces immune training in microglia.
Journal of neuroinflammation
Heng Y,Zhang X,Borggrewe M,van Weering HRJ,Brummer ML,Nijboer TW,Joosten LAB,Netea MG,Boddeke EWGM,Laman JD,Eggen BJL
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Feb 22 00:00:00 EST 2021
Differential neurovirulence of Usutu virus lineages in mice and neuronal cells.
Journal of neuroinflammation
Clé M,Constant O,Barthelemy J,Desmetz C,Martin MF,Lapeyre L,Cadar D,Savini G,Teodori L,Monaco F,Schmidt-Chanasit J,Saiz JC,Gonzales G,Lecollinet S,Beck C,Gosselet F,Van de Perre P,Foulongne V,Salinas S,Simonin Y
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Wed Jan 06 00:00:00 EST 2021
Transcriptional Network Analysis Reveals the Role of miR-223-5p During Diabetic Corneal Epithelial Regeneration.
Frontiers in molecular biosciences
Zhang Y,Dou S,Qi X,Zhang Z,Qiao Y,Wang Y,Xie J,Jiang H,Zhang B,Zhou Q,Wang Q,Xie L
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunocytochemistry
Thu Apr 13 00:00:00 EDT 2023
Early Adolescence Prefrontal Cortex Alterations in Female Rats Lacking Dopamine Transporter.
Biomedicines
Illiano P,Leo D,Gainetdinov RR,Pardo M
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Western Blot
Fri Feb 05 00:00:00 EST 2021
Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation.
Nature
Jiao H,Wachsmuth L,Kumari S,Schwarzer R,Lin J,Eren RO,Fisher A,Lane R,Young GR,Kassiotis G,Kaiser WJ,Pasparakis M
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Wed Apr 01 00:00:00 EDT 2020
Macrophages Maintain Epithelium Integrity by Limiting Fungal Product Absorption.
Cell
Chikina AS,Nadalin F,Maurin M,San-Roman M,Thomas-Bonafos T,Li XV,Lameiras S,Baulande S,Henri S,Malissen B,Lacerda Mariano L,Barbazan J,Blander JM,Iliev ID,Matic Vignjevic D,Lennon-Duménil AM
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Oct 15 00:00:00 EDT 2020
The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching.
Immunity
Xu J,Zanvit P,Hu L,Tseng PY,Liu N,Wang F,Liu O,Zhang D,Jin W,Guo N,Han Y,Yin J,Cain A,Hoon MA,Wang S,Chen W
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Aug 18 00:00:00 EDT 2020
Emergence of a High-Plasticity Cell State during Lung Cancer Evolution.
Cancer cell
Marjanovic ND,Hofree M,Chan JE,Canner D,Wu K,Trakala M,Hartmann GG,Smith OC,Kim JY,Evans KV,Hudson A,Ashenberg O,Porter CBM,Bejnood A,Subramanian A,Pitter K,Yan Y,Delorey T,Phillips DR,Shah N,Chaudhary O,Tsankov A,Hollmann T,Rekhtman N,Massion PP,Poirier JT,Mazutis L,Li R,Lee JH,Amon A,Rudin CM,Jacks T,Regev A,Tammela T
11-0451-82 was used in Flow Cytometry to profile cellular transcriptomes of lung tumours at different stages.
Mon Aug 10 00:00:00 EDT 2020
Exposure to diesel exhaust particles increases susceptibility to invasive pneumococcal disease.
The Journal of allergy and clinical immunology
Shears RK,Jacques LC,Naylor G,Miyashita L,Khandaker S,Lebre F,Lavelle EC,Grigg J,French N,Neill DR,Kadioglu A
11-0451 was used in Flow cytometry/Cell sorting to determine whether exposure to DEPs could promote the progression of asymptomatic nasopharyngeal carriage of Streptococcus pneumoniae to invasive pneumococcal disease.
Wed Apr 01 00:00:00 EDT 2020
Exposure to diesel exhaust particles increases susceptibility to invasive pneumococcal disease.
The Journal of allergy and clinical immunology
Shears RK,Jacques LC,Naylor G,Miyashita L,Khandaker S,Lebre F,Lavelle EC,Grigg J,French N,Neill DR,Kadioglu A
11-0451 was used in Flow cytometry/Cell sorting to determine whether exposure to DEPs could promote the progression of asymptomatic nasopharyngeal carriage of Streptococcus pneumoniae to invasive pneumococcal disease.
Wed Apr 01 00:00:00 EDT 2020
FLASH Irradiation Spares Lung Progenitor Cells and Limits the Incidence of Radio-induced Senescence.
Clinical cancer research : an official journal of the American Association for Cancer Research
Fouillade C,Curras-Alonso S,Giuranno L,Quelennec E,Heinrich S,Bonnet-Boissinot S,Beddok A,Leboucher S,Karakurt HU,Bohec M,Baulande S,Vooijs M,Verrelle P,Dutreix M,Londoño-Vallejo A,Favaudon V
11-0451-81 was used in Immunocytochemistry to suggest that FLASH irradiation minimises DNA damage in normal cells, spares lung progenitor cells from excessive damage and reduces the risk of replicative senescence compared to conventional radiotherapy.
Sun Mar 15 00:00:00 EDT 2020
IgE Contributes to Atherosclerosis and Obesity by Affecting Macrophage Polarization, Macrophage Protein Network, and Foam Cell Formation.
Arteriosclerosis, thrombosis, and vascular biology
Zhang X,Li J,Luo S,Wang M,Huang Q,Deng Z,de Febbo C,Daoui A,Liew PX,Sukhova GK,Metso J,Jauhiainen M,Shi GP,Guo J
11-0451 was used in Flow cytometry/Cell sorting to demonstrate that IgE deficiency reduced atherosclerosis lesion burden, lesion lipid deposition, smooth muscle cell and endothelial cell contents, chemokine MCP (monocyte chemoattractant protein)-1 expression and macrophage accumulation.
Sun Mar 01 00:00:00 EST 2020
Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.
British journal of pharmacology
De Cicco P,Ercolano G,Rubino V,Terrazzano G,Ruggiero G,Cirino G,Ianaro A
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
CD49fhigh Defines a Distinct Skin Mesenchymal Stem Cell Population Capable of Hair Follicle Epithelial Cell Maintenance.
The Journal of investigative dermatology
Yang Z,Ma S,Cao R,Liu L,Cao C,Shen Z,Fu X,Yan L,Wang Q,Liu X,Xiao R
11-0451 was used in Flow cytometry/Cell sorting to lead to a deeper understanding of heterogeneity and the function of MSCs in the skin and may facilitate potential translational applications of these cells.
Sun Mar 01 00:00:00 EST 2020
M2 polarization of tumor-associated macrophages is dependent on integrin β3 via peroxisome proliferator-activated receptor-γ up-regulation in breast cancer.
Immunology
Shu Y,Qin M,Song Y,Tang Q,Huang Y,Shen P,Lu Y
11-0451-82 was used in Flow Cytometry to find a connection between integrin β3 and macrophage polarization.
Sat Aug 01 00:00:00 EDT 2020
Membrane expression of the estrogen receptor ERα is required for intercellular communications in the mammary epithelium.
Development (Cambridge, England)
Gagniac L,Rusidzé M,Boudou F,Cagnet S,Adlanmerini M,Jeannot P,Gaide N,Giton F,Besson A,Weyl A,Gourdy P,Raymond-Letron I,Arnal JF,Brisken C,Lenfant F
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Mar 11 00:00:00 EDT 2020
Specific microbiota enhances intestinal IgA levels by inducing TGF-β in T follicular helper cells of Peyer's patches in mice.
European journal of immunology
Beller A,Kruglov A,Durek P,von Goetze V,Werner K,Heinz GA,Ninnemann J,Lehmann K,Maier R,Hoffmann U,Riedel R,Heiking K,Zimmermann J,Siegmund B,Mashreghi MF,Radbruch A,Chang HD
11-0451-82 was used in Flow Cytometry to show that not eosinophils, but specific bacteria determine mucosal IgA production.
Mon Jun 01 00:00:00 EDT 2020
Dysfunction of B Cell Leading to Failure of Immunoglobulin Response Is Ameliorated by Dietary Silk Peptide in 14-Month-Old C57BL/6 Mice.
Frontiers in nutrition
Chei S,Oh HJ,Lee K,Jin H,Lee JY,Lee BY
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Dec 18 00:00:00 EST 2020
Effect of mesenchymal stem cell-derived exosomes on the induction of mouse tolerogenic dendritic cells.
Journal of cellular physiology
Shahir M,Mahmoud Hashemi S,Asadirad A,Varahram M,Kazempour-Dizaji M,Folkerts G,Garssen J,Adcock I,Mortaz E
11-0451 was used in Flow cytometry/Cell sorting to investigate the effects of mesenchymal stem cell-derived exosomes and to understand their role in modulating the mouse tolergenic dendritic cell immune responses.
Thu Oct 01 00:00:00 EDT 2020
Sema3A and HIF1α co-overexpressed iPSC-MSCs/HA scaffold facilitates the repair of calvarial defect in a mouse model.
Journal of cellular physiology
Li J,Wang T,Li C,Wang Z,Wang P,Zheng L
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Detection of Synaptic Proteins in Microglia by Flow Cytometry.
Frontiers in molecular neuroscience
Brioschi S,d'Errico P,Amann LS,Janova H,Wojcik SM,Meyer-Luehmann M,Rajendran L,Wieghofer P,Paolicelli RC,Biber K
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Nov 03 00:00:00 EST 2020
Noncanonical function of long myosin light chain kinase in increasing ER-PM junctions and augmentation of SOCE.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Srivastava N,Tauseef M,Amin R,Joshi B,Joshi JC,Kini V,Klomp J,Li W,Knezevic N,Barbera N,Siddiqui S,Obukhov A,Karginov A,Levitan I,Komarova Y,Mehta D
11-0451 was used in Flow cytometry/Cell sorting to show that thapsigargin and thrombin-induced SOCE was markedly reduced in Mylk-L-/- endothelial cells (EC) or MYLK-L-depleted human EC.
Tue Sep 01 00:00:00 EDT 2020
Quantitative single-cell interactomes in normal and virus-infected mouse lungs.
Disease models & mechanisms
Cain MP,Hernandez BJ,Chen J
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunocytochemistry
Fri Jun 26 00:00:00 EDT 2020
Extracellular HMGB-1 activates inflammatory signaling in tendon cells and tissues.
Therapeutic advances in chronic disease
Zhang C,Gu X,Zhao G,Wang W,Shao J,Zhu J,Yuan T,Sun J,Nie D,Zhou Y
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sun Apr 17 00:00:00 EDT 2022
Extracellular HMGB-1 activates inflammatory signaling in tendon cells and tissues.
Therapeutic advances in chronic disease
Zhang C,Gu X,Zhao G,Wang W,Shao J,Zhu J,Yuan T,Sun J,Nie D,Zhou Y
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sun Apr 17 00:00:00 EDT 2022
Resveratrol rescues TNF‑α‑induced inhibition of osteogenesis in human periodontal ligament stem cells via the ERK1/2 pathway.
Molecular medicine reports
Yuan J,Wang X,Ma D,Gao H,Zheng D,Zhang J
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Effects of CD4+ T lymphocytes from ovariectomized mice on bone marrow mesenchymal stem cell proliferation and osteogenic differentiation.
Experimental and therapeutic medicine
Shao BY,Wang L,Yu Y,Chen L,Gan N,Huang WM
11-0451 was used in Flow cytometry/Cell sorting to investigate the effects of T cells on the proliferation and osteogenic differentiation of bone marrow mesenchymal stem cells (BMMSCs).
Sun Nov 01 00:00:00 EDT 2020
Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers.
Nature communications
Okazaki K,Anzawa H,Liu Z,Ota N,Kitamura H,Onodera Y,Alam MM,Matsumaru D,Suzuki T,Katsuoka F,Tadaka S,Motoike I,Watanabe M,Hayasaka K,Sakurada A,Okada Y,Yamamoto M,Suzuki T,Kinoshita K,Sekine H,Motohashi H
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Nov 20 00:00:00 EST 2020
Eosinophils improve cardiac function after myocardial infarction.
Nature communications
Liu J,Yang C,Liu T,Deng Z,Fang W,Zhang X,Li J,Huang Q,Liu C,Wang Y,Yang D,Sukhova GK,Lindholt JS,Diederichsen A,Rasmussen LM,Li D,Newton G,Luscinskas FW,Liu L,Libby P,Wang J,Guo J,Shi GP
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
Ly6cLo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation.
Scientific reports
Alkhani A,Levy CS,Tsui M,Rosenberg KA,Polovina K,Mattis AN,Mack M,Van Dyken S,Wang BM,Maher JJ,Nijagal A
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Apr 28 00:00:00 EDT 2020
Stromal CCL2 Signaling Promotes Mammary Tumor Fibrosis through Recruitment of Myeloid-Lineage Cells.
Cancers
Kuziel G,Thompson V,D'Amato JV,Arendt LM
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Jul 28 00:00:00 EDT 2020
Small GTPase RAB6 deficiency promotes alveolar progenitor cell renewal and attenuates PM2.5-induced lung injury and fibrosis.
Cell death & disease
Yang L,Liu G,Li X,Xia Z,Wang Y,Lin W,Zhang W,Zhang W,Li X
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sun Oct 04 00:00:00 EDT 2020
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation.
Nature communications
Kim JM,Yang YS,Park KH,Ge X,Xu R,Li N,Song M,Chun H,Bok S,Charles JF,Filhol-Cochet O,Boldyreff B,Dinter T,Yu PB,Kon N,Gu W,Takarada T,Greenblatt MB,Shim JH
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri May 08 00:00:00 EDT 2020
Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement.
eLife
Kalinski AL,Yoon C,Huffman LD,Duncker PC,Kohen R,Passino R,Hafner H,Johnson C,Kawaguchi R,Carbajal KS,Jara JS,Hollis E,Geschwind DH,Segal BM,Giger RJ
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Dec 02 00:00:00 EST 2020
Resolvin D1 supports skeletal myofiber regeneration via actions on myeloid and muscle stem cells.
JCI insight
Markworth JF,Brown LA,Lim E,Floyd C,Larouche J,Castor-Macias JA,Sugg KB,Sarver DC,Macpherson PC,Davis C,Aguilar CA,Maddipati KR,Brooks SV
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations.
Journal of neuroinflammation
Lowe PP,Morel C,Ambade A,Iracheta-Vellve A,Kwiatkowski E,Satishchandran A,Furi I,Cho Y,Gyongyosi B,Catalano D,Lefebvre E,Fischer L,Seyedkazemi S,Schafer DP,Szabo G
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Oct 09 00:00:00 EDT 2020
Delayed microglial depletion after spinal cord injury reduces chronic inflammation and neurodegeneration in the brain and improves neurological recovery in male mice.
Theranostics
Li Y,Ritzel RM,Khan N,Cao T,He J,Lei Z,Matyas JJ,Sabirzhanov B,Liu S,Li H,Stoica BA,Loane DJ,Faden AI,Wu J
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Jun 01 00:00:00 EDT 2021
Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease.
Journal of neuroinflammation
Schröder N,Schaffrath A,Welter JA,Putzka T,Griep A,Ziegler P,Brandt E,Samer S,Heneka MT,Kaddatz H,Zhan J,Kipp E,Pufe T,Tauber SC,Kipp M,Brandenburg LO
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Apr 24 00:00:00 EDT 2020
Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease.
Journal of neuroinflammation
Schröder N,Schaffrath A,Welter JA,Putzka T,Griep A,Ziegler P,Brandt E,Samer S,Heneka MT,Kaddatz H,Zhan J,Kipp E,Pufe T,Tauber SC,Kipp M,Brandenburg LO
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Apr 24 00:00:00 EDT 2020
Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.
JCI insight
Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Aug 20 00:00:00 EDT 2020
Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartments.
Nature communications
Jandke A,Melandri D,Monin L,Ushakov DS,Laing AG,Vantourout P,East P,Nitta T,Narita T,Takayanagi H,Feederle R,Hayday A
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Jul 28 00:00:00 EDT 2020
Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models.
Communications biology
Waaler J,Mygland L,Tveita A,Strand MF,Solberg NT,Olsen PA,Aizenshtadt A,Fauskanger M,Lund K,Brinch SA,Lycke M,Dybing E,Nygaard V,Bøe SL,Heintz KM,Hovig E,Hammarström C,Corthay A,Krauss S
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Apr 24 00:00:00 EDT 2020
The bone marrow niche components are adversely affected in sepsis.
Molecular biomedicine
Yin F,Qian H,Duan C,Ning B
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Oct 20 00:00:00 EDT 2020
A Synthetic Small Molecule F240B Decreases NLRP3 Inflammasome Activation by Autophagy Induction.
Frontiers in immunology
Wu CH,Gan CH,Li LH,Chang JC,Chen ST,Menon MP,Cheng SM,Yang SP,Ho CL,Chernikov OV,Lin CH,Lam Y,Hua KF
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Jun 23 00:00:00 EDT 2021
A Synthetic Small Molecule F240B Decreases NLRP3 Inflammasome Activation by Autophagy Induction.
Frontiers in immunology
Wu CH,Gan CH,Li LH,Chang JC,Chen ST,Menon MP,Cheng SM,Yang SP,Ho CL,Chernikov OV,Lin CH,Lam Y,Hua KF
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Jun 23 00:00:00 EDT 2021
CNS Immune Profiling in a Dengue Virus-Infected Immunocompetent Outbred ICR Mice Strain.
Frontiers in cellular and infection microbiology
Shen TJ,Chen CL,Jhan MK,Tseng PC,Lin CF
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Jun 17 00:00:00 EDT 2021
Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages.
Stem cell research & therapy
Liu J,Qiu X,Lv Y,Zheng C,Dong Y,Dou G,Zhu B,Liu A,Wang W,Zhou J,Liu S,Liu S,Gao B,Jin Y
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Nov 27 00:00:00 EST 2020
Phosphatase SHP1 impedes mesenchymal stromal cell immunosuppressive capacity modulated by JAK1/STAT3 and P38 signals.
Cell & bioscience
Jiang M,Ye J,Wang X,Li N,Wang Y,Shi Y
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Apr 14 00:00:00 EDT 2022
A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors.
eLife
Crowley L,Cambuli F,Aparicio L,Shibata M,Robinson BD,Xuan S,Li W,Hibshoosh H,Loda M,Rabadan R,Shen MM
11-0451 was used in Flow cytometry/Cell sorting to elucidate new prostate epithelial progenitors, and help resolve long-standing questions about anatomical relationships between the mouse and human prostate.
Fri Sep 11 00:00:00 EDT 2020
Osteopontin/secreted phosphoprotein-1 behaves as a molecular brake regulating the neuroinflammatory response to chronic viral infection.
Journal of neuroinflammation
Mahmud FJ,Du Y,Greif E,Boucher T,Dannals RF,Mathews WB,Pomper MG,Sysa-Shah P,Metcalf Pate KA,Lyons C,Carlson B,Chacona M,Brown AM
11-0451 was used in Flow cytometry/Cell sorting to propose that osteopontin may act as a molecular brake within the brain in order to regulate the inflammatory response to chronic viral infections, such as HIV.
Thu Sep 17 00:00:00 EDT 2020
Interstitial Cell Remodeling Promotes Aberrant Adipogenesis in Dystrophic Muscles.
Cell reports
Camps J,Breuls N,Sifrim A,Giarratana N,Corvelyn M,Danti L,Grosemans H,Vanuytven S,Thiry I,Belicchi M,Meregalli M,Platko K,MacDonald ME,Austin RC,Gijsbers R,Cossu G,Torrente Y,Voet T,Sampaolesi M
11-0451 was used in Flow cytometry/Cell sorting to decomplexify interstitial cell populations in healthy and dystrophic skeletal muscles using single-cell RNA sequencing.
Tue May 05 00:00:00 EDT 2020
Mesenchymal stem cells reduce alcoholic hepatitis in mice via suppression of hepatic neutrophil and macrophage infiltration, and of oxidative stress.
PloS one
Wan YM,Li ZQ,Liu C,He YF,Wang MJ,Wu XN,Zhang Y,Li YH
11-0451-82 was used in Flow Cytometry to investigate whether MSCs are effective in treating mice with alcoholic hepatitis (AH) and its underlying mechanism.
Thu May 07 00:00:00 EDT 2020
SPHK2-Generated S1P in CD11b+ Macrophages Blocks STING to Suppress the Inflammatory Function of Alveolar Macrophages.
Cell reports
Joshi JC,Joshi B,Rochford I,Rayees S,Akhter MZ,Baweja S,Chava KR,Tauseef M,Abdelkarim H,Natarajan V,Gaponenko V,Mehta D
11-0451 was used in Flow cytometry/Cell sorting to demonstrate the anti-inflammatory regulation of monocyte-derived macrophages by acting on type 1 interferon gene signalling.
Tue Mar 24 00:00:00 EDT 2020
Gasdermin D in macrophages restrains colitis by controlling cGAS-mediated inflammation.
Science advances
Ma C,Yang D,Wang B,Wu C,Wu Y,Li S,Liu X,Lassen K,Dai L,Yang S
11-0451 was used in Flow cytometry/Cell sorting to provide the first demonstration of GSDMD's role in controlling colitis and a detailed delineation of the underlying mechanism.
Fri May 01 00:00:00 EDT 2020
Digestion of Whole Mouse Eyes for Multi-Parameter Flow Cytometric Analysis of Mononuclear Phagocytes.
Journal of visualized experiments : JoVE
Droho S,Cuda CM,Lavine JA
11-0451 was used in Flow cytometry/Cell sorting to identify different populations of mononuclear phagocytes using whole mouse eyes and flow cytometry.
Wed Jun 17 00:00:00 EDT 2020
Secreted Phospholipase PLA2G2D Contributes to Metabolic Health by Mobilizing ω3 Polyunsaturated Fatty Acids in WAT.
Cell reports
Sato H,Taketomi Y,Miki Y,Murase R,Yamamoto K,Murakami M
11-0451 was used in Flow cytometry/Cell sorting to present findings underscore the contribution of the macrophage-driven PLA2G2D-ω3 PUFA axis to metabolic health.
Tue May 05 00:00:00 EDT 2020
Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output.
Cell
Zhao Q,Liu J,Deng H,Ma R,Liao JY,Liang H,Hu J,Li J,Guo Z,Cai J,Xu X,Gao Z,Su S
11-0451-82 was used in Flow cytometry/Cell sorting to identify a mitochondrial circRNA that drives metaflammation and serves as a therapeutic target for NASH.
Thu Oct 01 00:00:00 EDT 2020
Glucocorticoids Promote the Onset of Acute Experimental Colitis and Cancer by Upregulating mTOR Signaling in Intestinal Epithelial Cells.
Cancers
Zhang Z,Dong L,Jia A,Chen X,Yang Q,Wang Y,Wang Y,Liu R,Cao Y,He Y,Bi Y,Liu G
11-0451 was used in Flow cytometry/Cell sorting to indicate that glucocorticoid-induced mTOR signaling in epithelial cells is required in the early stages of acute ulcerative colitis by modulating the dynamics of innate immune cell recruitment and activation.
Sat Apr 11 00:00:00 EDT 2020
Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity.
Nature communications
von Roemeling CA,Wang Y,Qie Y,Yuan H,Zhao H,Liu X,Yang Z,Yang M,Deng W,Bruno KA,Chan CK,Lee AS,Rosenfeld SS,Yun K,Johnson AJ,Mitchell DA,Jiang W,Kim BYS
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Fri Mar 20 00:00:00 EDT 2020
NPM1 upregulates the transcription of PD-L1 and suppresses T cell activity in triple-negative breast cancer.
Nature communications
Qin G,Wang X,Ye S,Li Y,Chen M,Wang S,Qin T,Zhang C,Li Y,Long Q,Hu H,Shi D,Li J,Zhang K,Zhai Q,Tang Y,Kang T,Lan P,Xie F,Lu J,Deng W
11-0451-82 was used in Flow Cytometry to verify that triple-negative breast cancer (TNBC) has higher PD-L1 expression than other subtypes.
Fri Apr 03 00:00:00 EDT 2020
FAM13A affects body fat distribution and adipocyte function.
Nature communications
Fathzadeh M,Li J,Rao A,Cook N,Chennamsetty I,Seldin M,Zhou X,Sangwung P,Gloudemans MJ,Keller M,Attie A,Yang J,Wabitsch M,Carcamo-Orive I,Tada Y,Lusis AJ,Shin MK,Molony CM,McLaughlin T,Reaven G,Montgomery SB,Reilly D,Quertermous T,Ingelsson E,Knowles JW
11-0451-82 was used in Flow Cytometry to indicate that GWAS-associated variants within the FAM13A locus alter adipose FAM13A expression, which in turn, regulates adipocyte differentiation and contribute to changes in body fat distribution.
Thu Mar 19 00:00:00 EDT 2020
Study of Usutu virus neuropathogenicity in mice and human cellular models.
PLoS neglected tropical diseases
Clé M,Barthelemy J,Desmetz C,Foulongne V,Lapeyre L,Bolloré K,Tuaillon E,Erkilic N,Kalatzis V,Lecollinet S,Beck C,Pirot N,Glasson Y,Gosselet F,Alvarez Martinez MT,Van de Perre P,Salinas S,Simonin Y
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Wed Apr 01 00:00:00 EDT 2020
Zika Virus Infection Promotes Local Inflammation, Cell Adhesion Molecule Upregulation, and Leukocyte Recruitment at the Blood-Brain Barrier.
mBio
Clé M,Desmetz C,Barthelemy J,Martin MF,Constant O,Maarifi G,Foulongne V,Bolloré K,Glasson Y,De Bock F,Blaquiere M,Dehouck L,Pirot N,Tuaillon E,Nisole S,Najioullah F,Van de Perre P,Cabié A,Marchi N,Gosselet F,Simonin Y,Salinas S
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Tue Aug 04 00:00:00 EDT 2020
RNase A Treatment Interferes With Leukocyte Recruitment, Neutrophil Extracellular Trap Formation, and Angiogenesis in Ischemic Muscle Tissue.
Frontiers in physiology
Lasch M,Kumaraswami K,Nasiscionyte S,Kircher S,van den Heuvel D,Meister S,Ishikawa-Ankerhold H,Deindl E
11-0451-82 was used in Immunohistochemistry (Frozen) to investigate whether RNase A shows a pro- or anti-angiogenic effect.
Fri Nov 27 00:00:00 EST 2020
PPARγ inhibition boosts efficacy of PD-L1 Checkpoint Blockade Immunotherapy against Murine Melanoma in a sexually dimorphic manner.
International journal of biological sciences
Wu B,Sun X,Yuan B,Ge F,Gupta HB,Chiang HC,Li J,Hu Y,Curiel TJ,Li R
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Aug 23 00:00:00 EDT 2021
Mesenchymal Stromal Cell-Derived Exosomes Contribute to Epithelial Regeneration in Experimental Inflammatory Bowel Disease.
Cellular and molecular gastroenterology and hepatology
Barnhoorn MC,Plug L,Jonge ESMM,Molenkamp D,Bos E,Schoonderwoerd MJA,Corver WE,van der Meulen-de Jong AE,Verspaget HW,Hawinkels LJAC
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon May 10 00:00:00 EDT 2021
A Subset of Type I Conventional Dendritic Cells Controls Cutaneous Bacterial Infections through VEGFα-Mediated Recruitment of Neutrophils.
Immunity
Janela B,Patel AA,Lau MC,Goh CC,Msallam R,Kong WT,Fehlings M,Hubert S,Lum J,Simoni Y,Malleret B,Zolezzi F,Chen J,Poidinger M,Satpathy AT,Briseno C,Wohn C,Malissen B,Murphy KM,Maini AA,Vanhoutte L,Guilliams M,Vial E,Hennequin L,Newell E,Ng LG,Musette P,Yona S,Hacini-Rachinel F,Ginhoux F
11-0451 was used in Flow cytometry/Cell sorting to show that skin cDC1s are essential regulators of the innate response in cutaneous immunity and have roles beyond classical antigen presentation.
Tue Apr 16 00:00:00 EDT 2019
IGF-2 Preprograms Maturing Macrophages to Acquire Oxidative Phosphorylation-Dependent Anti-inflammatory Properties.
Cell metabolism
Du L,Lin L,Li Q,Liu K,Huang Y,Wang X,Cao K,Chen X,Cao W,Li F,Shao C,Wang Y,Shi Y
11-0451-82 was used in Flow Cytometry to demonstrate that shaping macrophage responsiveness by IGF-2 is effective in managing inflammatory diseases, and the OXPHOS commitment can be preset to determine the anti-inflammatory fate of macrophages.
Tue Jun 04 00:00:00 EDT 2019
Collagenase Nanoparticles Enhance the Penetration of Drugs into Pancreatic Tumors.
ACS nano
Zinger A,Koren L,Adir O,Poley M,Alyan M,Yaari Z,Noor N,Krinsky N,Simon A,Gibori H,Krayem M,Mumblat Y,Kasten S,Ofir S,Fridman E,Milman N,Lübtow MM,Liba L,Shklover J,Shainsky-Roitman J,Binenbaum Y,Hershkovitz D,Gil Z,Dvir T,Luxenhofer R,Satchi-Fainaro R,Schroeder A
11-0451 was used in Flow cytometry/Cell sorting to investigate the effect of pretreatment with a proteolytic enzyme nanoparticle system disassembles the pancreatic ductal adenocarcinoma collagen stroma and increases drug penetration into the tumout.
Tue Oct 22 00:00:00 EDT 2019
Gasdermin D in peripheral myeloid cells drives neuroinflammation in experimental autoimmune encephalomyelitis.
The Journal of experimental medicine
Li S,Wu Y,Yang D,Wu C,Ma C,Liu X,Moynagh PN,Wang B,Hu G,Yang S
11-0451-82 was used in Flow Cytometry to study how GSDMD deficiency in peripheral myeloid cells impaired the infiltration of immune cells into the CNS, leading to the suppression of neuroinflammation and demyelination.
Mon Nov 04 00:00:00 EST 2019
ABRO1 promotes NLRP3 inflammasome activation through regulation of NLRP3 deubiquitination.
The EMBO journal
Ren G,Zhang X,Xiao Y,Zhang W,Wang Y,Ma W,Wang X,Song P,Lai L,Chen H,Zhan Y,Zhang J,Yu M,Ge C,Li C,Yin R,Yang X
11-0451 was used in Flow cytometry/Cell sorting to study an ABRO1-mediated regulatory signaling system that controls activation of the NLRP3 inflammasome.
Fri Mar 15 00:00:00 EDT 2019
Low-Dose Apatinib Optimizes Tumor Microenvironment and Potentiates Antitumor Effect of PD-1/PD-L1 Blockade in Lung Cancer.
Cancer immunology research
Zhao S,Ren S,Jiang T,Zhu B,Li X,Zhao C,Jia Y,Shi J,Zhang L,Liu X,Qiao M,Chen X,Su C,Yu H,Zhou C,Zhang J,Camidge DR,Hirsch FR
11-0451 was used in Flow cytometry/Cell sorting to analyze the impact of apatinib, a smallmolecule VEGFR2-TKI, on the TME in murine Lewis lung carcinoma (LLC) models at different doses alone and in combination with an anti–PD-L1.
Mon Apr 01 00:00:00 EDT 2019
Schistosoma japonicum extracellular vesicle miRNA cargo regulates host macrophage functions facilitating parasitism.
PLoS pathogens
Liu J,Zhu L,Wang J,Qiu L,Chen Y,Davis RE,Cheng G
11-0451-82 was used in Flow Cytometry to report that extracellular vesicles (EVs) released from Schistosoma japonicum are taken up primarily by macrophages and other host peripheral blood immune cells and their miRNA cargo transferred into recipient cells.
Sat Jun 01 00:00:00 EDT 2019
The ROP16III-dependent early immune response determines the subacute CNS immune response and type III Toxoplasma gondii survival.
PLoS pathogens
Tuladhar S,Kochanowsky JA,Bhaskara A,Ghotmi Y,Chandrasekaran S,Koshy AA
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
Distinct Tie2 tyrosine phosphorylation sites dictate phenotypic switching in endothelial progenitor cells.
Journal of cellular physiology
Siavashi V,Nassiri SM,Rahbarghazi R,Mohseni Z,Sharifi AM
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed May 01 00:00:00 EDT 2019
Protumoral bone marrow-derived cells migrate via Gβγ-dependent signaling pathways and exhibit a complex repertoire of RhoGEFs.
Journal of cell communication and signaling
Cervantes-Villagrana RD,Color-Aparicio VM,Reyes-Cruz G,Vázquez-Prado J
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sat Jun 01 00:00:00 EDT 2019
Extracellular RNAs from lung cancer cells activate epithelial cells and induce neutrophil extracellular traps.
International journal of oncology
Li Y,Yang Y,Gan T,Zhou J,Hu F,Hao N,Yuan B,Chen Y,Zhang M
11-0451 was used in Flow cytometry/Cell sorting to investigate the cross‚talk of tumor exRNAs and neutrophil extracellular traps in lung cancer.
Mon Jul 01 00:00:00 EDT 2019
Pericyte transplantation improves skeletal muscle recovery following hindlimb immobilization.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Munroe M,Dvoretskiy S,Lopez A,Leong J,Dyle MC,Kong H,Adams CM,Boppart MD
11-0451 was used in Flow cytometry/Cell sorting to provide the first evidence that pericytes effectively rehabilitate skeletal muscle mass following disuse atrophy.
Sat Jun 01 00:00:00 EDT 2019
Critical Adverse Impact of IL-6 in Acute Pneumovirus Infection.
Journal of immunology (Baltimore, Md. : 1950)
Percopo CM,Ma M,Brenner TA,Krumholz JO,Break TJ,Laky K,Rosenberg HF
11-0451 was used in Flow cytometry/Cell sorting to examine the role of the pleiotropic cytokine IL-6 in acute infection with pneumonia virus of mice.
Fri Feb 01 00:00:00 EST 2019
PD-1 inhibitors dependent CD8+ T cells inhibit mouse colon cancer cell metastasis.
OncoTargets and therapy
Gao CE,Zhang M,Song Q,Dong J
11-0451-82 was used in Flow Cytometry to investigate the function of PD-1 inhibitor on the metastasisi of mouse colon cancer cells.
Mon Apr 11 00:00:00 EDT 2022
Comparison between curcumin and all-trans retinoic acid in the osteogenic differentiation of mouse bone marrow mesenchymal stem cells.
Experimental and therapeutic medicine
Ahmed MF,El-Sayed AK,Chen H,Zhao R,Yusuf MS,Zuo Q,Zhang Y,Li B
11-0451 was used in Flow cytometry/Cell sorting to examine the effects of all-trans retinoic acid and curcumin on the osteogenic differentiation of mouse bone marrow mesenchymal stem cells.
Wed May 01 00:00:00 EDT 2019
Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection-Induced Neuropathic Pain.
Pain research & management
Sheng WS,Chauhan P,Hu S,Prasad S,Lokensgard JR
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Dec 16 00:00:00 EST 2019
Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.
Anti-cancer drugs
Zhou Y,Fu C,Kong Y,Pan D,Wang Y,Huang S,Li Z,Ning Z,Lu X,Shan S,Xin L
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
CSF1R antagonism limits local restimulation of antiviral CD8+ T cells during viral encephalitis.
Journal of neuroinflammation
Funk KE,Klein RS
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Jan 31 00:00:00 EST 2019
Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins.
eLife
Lim J,Park H,Heisler J,Maculins T,Roose-Girma M,Xu M,Mckenzie B,van Lookeren Campagne M,Newton K,Murthy A
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Jul 09 00:00:00 EDT 2019
Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model.
Nature communications
Zhong L,Xu Y,Zhuo R,Wang T,Wang K,Huang R,Wang D,Gao Y,Zhu Y,Sheng X,Chen K,Wang N,Zhu L,Can D,Marten Y,Shinohara M,Liu CC,Du D,Sun H,Wen L,Xu H,Bu G,Chen XF
11-0451-82 was used in Flow Cytometry to demonstrate a protective role of sTREM2 against amyloid pathology and related toxicity and suggests that increasing sTREM2 can be explored for Alzheimer's disease therapy.
Mon Mar 25 00:00:00 EDT 2019
The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression.
Nature communications
Huang J,Zhao L,Fan Y,Liao L,Ma PX,Xiao G,Chen D
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Jun 28 00:00:00 EDT 2019
MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.
Journal for immunotherapy of cancer
Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Nov 28 00:00:00 EST 2019
Early Pregnancy Human Decidua is Enriched with Activated, Fully Differentiated and Pro-Inflammatory Gamma/Delta T Cells with Diverse TCR Repertoires.
International journal of molecular sciences
Terzieva A,Dimitrova V,Djerov L,Dimitrova P,Zapryanova S,Hristova I,Vangelov I,Dimova T
11-0451 was used in Flow cytometry/Cell sorting to investigate the proportion phenotype and TCR γ and δ repertoires of γδ T cells at the maternal-fetal interface and in the blood of pregnant women.
Tue Feb 05 00:00:00 EST 2019
Muscularis Propria Macrophages Alter the Proportion of Nitrergic but Not Cholinergic Gastric Myenteric Neurons.
Cellular and molecular gastroenterology and hepatology
Cipriani G,Terhaar ML,Eisenman ST,Ji S,Linden DR,Wright AM,Sha L,Ordog T,Szurszewski JH,Gibbons SJ,Farrugia G
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Jun 04 00:00:00 EDT 2019
Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis.
eLife
Walsh CM,Hill RZ,Schwendinger-Schreck J,Deguine J,Brock EC,Kucirek N,Rifi Z,Wei J,Gronert K,Brem RB,Barton GM,Bautista DM
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Mon Oct 21 00:00:00 EDT 2019
Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis.
eLife
Walsh CM,Hill RZ,Schwendinger-Schreck J,Deguine J,Brock EC,Kucirek N,Rifi Z,Wei J,Gronert K,Brem RB,Barton GM,Bautista DM
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Mon Oct 21 00:00:00 EDT 2019
Exposure to Cigarette Smoke Augments Post-ischemic Brain Injury and Inflammation via Mobilization of Neutrophils and Monocytes.
Frontiers in immunology
Li H,Li X,Gao S,Wang D,Gao X,Li Y,Wang X,Cui Z,Ma H,Liu Q,Li M
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
Multi-parametric flow cytometry staining procedure for analyzing tumor-infiltrating immune cells following oncolytic herpes simplex virus immunotherapy in intracranial glioblastoma.
Journal of biological methods
Bommareddy PK,Lowe DB,Kaufman HL,Rabkin SD,Saha D
11-0451 was used in Flow cytometry/Cell sorting to describe a step-by-step 11-color protocol to stain tumor-infiltrating immune cells in glioblastoma following oncolytic herpes virotherapy.
Thu Oct 01 00:00:00 EDT 2020
NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis.
Nature communications
Ershaid N,Sharon Y,Doron H,Raz Y,Shani O,Cohen N,Monteran L,Leider-Trejo L,Ben-Shmuel A,Yassin M,Gerlic M,Ben-Baruch A,Pasmanik-Chor M,Apte R,Erez N
11-0451-82 was used in Flow Cytometry to find that fibroblasts sense damage-associated molecular patterns (DAMPs), and in response activate the NLRP3 inflammasome pathway, resulting in instigation of pro-inflammatory signalling and secretion of IL-1β.
Thu Sep 26 00:00:00 EDT 2019
Germ-Free Mice Exhibit Mast Cells With Impaired Functionality and Gut Homing and Do Not Develop Food Allergy.
Frontiers in immunology
Schwarzer M,Hermanova P,Srutkova D,Golias J,Hudcovic T,Zwicker C,Sinkora M,Akgün J,Wiedermann U,Tuckova L,Kozakova H,Schabussova I
11-0451 was used in Flow cytometry/Cell sorting to study the the relationship between gut microbiota and mucosal mast cells in the context of food allergies.
Thu Jan 16 00:00:00 EST 2020
Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy.
Nature communications
Welc SS,Flores I,Wehling-Henricks M,Ramos J,Wang Y,Bertoni C,Tidball JG
11-0451 was used in Flow cytometry/Cell sorting to study the effect of expression of a therapeutic transgene in leukocyte progenitors that invade muscle on selective and timely delivery to diseased muscle.
Wed Jun 26 00:00:00 EDT 2019
Identification of functional lipid metabolism biomarkers of brown adipose tissue aging.
Molecular metabolism
Gohlke S,Zagoriy V,Cuadros Inostroza A,Méret M,Mancini C,Japtok L,Schumacher F,Kuhlow D,Graja A,Stephanowitz H,Jähnert M,Krause E,Wernitz A,Petzke KJ,Schürmann A,Kleuser B,Schulz TJ
11-0451 was used in Flow cytometry/Cell sorting to execute analysis which identifies biomarkers of brown adipose tissue aging and the molecular mechanisms that could contribute to brown adipocyte degradation.
Sat Jun 01 00:00:00 EDT 2019
FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy.
eLife
Diaz Osterman CJ,Ozmadenci D,Kleinschmidt EG,Taylor KN,Barrie AM,Jiang S,Bean LM,Sulzmaier FJ,Jean C,Tancioni I,Anderson K,Uryu S,Cordasco EA,Li J,Chen XL,Fu G,Ojalill M,Rappu P,Heino J,Mark AM,Xu G,Fisch KM,Kolev VN,Weaver DT,Pachter JA,Győrffy B,McHale MT,Connolly DC,Molinolo A,Stupack DG,Schlaepfer DD
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Sep 03 00:00:00 EDT 2019
Club cells form lung adenocarcinomas and maintain the alveoli of adult mice.
eLife
Spella M,Lilis I,Pepe MA,Chen Y,Armaka M,Lamort AS,Zazara DE,Roumelioti F,Vreka M,Kanellakis NI,Wagner DE,Giannou AD,Armenis V,Arendt KA,Klotz LV,Toumpanakis D,Karavana V,Zakynthinos SG,Giopanou I,Marazioti A,Aidinis V,Sotillo R,Stathopoulos GT
11-0451-82 was used in Flow Cytometry to study the cellular origins of environmental-induced lung tumors and of the dysfunctional airway and alveolar epithelial turnover observed with chronic lung diseases by combining mouse models of genetic labeling and ablation of airway (club) and alveolar cells with exposure to environmental noxious and carcinogenic agents.
Wed May 29 00:00:00 EDT 2019
A MST1-FOXO1 cascade establishes endothelial tip cell polarity and facilitates sprouting angiogenesis.
Nature communications
Kim YH,Choi J,Yang MJ,Hong SP,Lee CK,Kubota Y,Lim DS,Koh GY
11-0451-82 was used in Flow Cytometry to delineate a crucial coupling between extracellular hypoxia and an intracellular reactive oxygen species-MST1-FOXO1 cascade in establishing endothelial tip cell polarity during sprouting angiogenesis.
Tue Feb 19 00:00:00 EST 2019
PDGFRα+ stromal adipocyte progenitors transition into epithelial cells during lobulo-alveologenesis in the murine mammary gland.
Nature communications
Joshi PA,Waterhouse PD,Kasaian K,Fang H,Gulyaeva O,Sul HS,Boutros PC,Khokha R
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Apr 15 00:00:00 EDT 2019
Growth Factor Screening in Dystrophic Muscles Reveals PDGFB/PDGFRB-Mediated Migration of Interstitial Stem Cells.
International journal of molecular sciences
Camps J,Grosemans H,Gijsbers R,Maes C,Sampaolesi M
11-0451 was used in Flow cytometry/Cell sorting to determine which chemokines are expressed in dystrophic muscles undergoing tissue remodelling.
Tue Mar 05 00:00:00 EST 2019
Growth Factor Screening in Dystrophic Muscles Reveals PDGFB/PDGFRB-Mediated Migration of Interstitial Stem Cells.
International journal of molecular sciences
Camps J,Grosemans H,Gijsbers R,Maes C,Sampaolesi M
11-0451 was used in Flow cytometry/Cell sorting to determine which chemokines are expressed in dystrophic muscles undergoing tissue remodelling.
Tue Mar 05 00:00:00 EST 2019
Circuit Design Features of a Stable Two-Cell System.
Cell
Zhou X,Franklin RA,Adler M,Jacox JB,Bailis W,Shyer JA,Flavell RA,Mayo A,Alon U,Medzhitov R
11-0451 was used in Flow cytometry/Cell sorting to illustrate principles of cell circuit design and provide a quantitative perspective on cell interactions.
Thu Feb 08 00:00:00 EST 2018
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
Chanzyme TRPM7 Mediates the Ca2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation.
Immunity
Schappe MS,Szteyn K,Stremska ME,Mendu SK,Downs TK,Seegren PV,Mahoney MA,Dixit S,Krupa JK,Stipes EJ,Rogers JS,Adamson SE,Leitinger N,Desai BN
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Jan 16 00:00:00 EST 2018
Gain-of-Function Mutation of Card14 Leads to Spontaneous Psoriasis-like Skin Inflammation through Enhanced Keratinocyte Response to IL-17A.
Immunity
Wang M,Zhang S,Zheng G,Huang J,Songyang Z,Zhao X,Lin X
11-0451 was used in Flow cytometry/Cell sorting to show CARMA2 serves as a key mediator of IL-17A signaling and its constitutive activation in keratinocytes leads to the onset of psoriasis.
Tue Jul 17 00:00:00 EDT 2018
E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.
Immunity
Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Feb 20 00:00:00 EST 2018
Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling.
Cell stem cell
Verma M,Asakura Y,Murakonda BSR,Pengo T,Latroche C,Chazaud B,McLoon LK,Asakura A
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Oct 04 00:00:00 EDT 2018
Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury.
The Journal of clinical investigation
Lau A,Chung H,Komada T,Platnich JM,Sandall CF,Choudhury SR,Chun J,Naumenko V,Surewaard BG,Nelson MC,Ulke-Lemée A,Beck PL,Benediktsson H,Jevnikar AM,Snelgrove SL,Hickey MJ,Senger DL,James MT,Macdonald JA,Kubes P,Jenne CN,Muruve DA
11-0451 was used in Flow cytometry/Cell sorting to show that CI-AKI is a multistep process that involves immune surveillance by resident and infiltrating renal phagocytes, Nlrp3-dependent inflammation, and the tubular reabsorption of contrast via dipeptidase-1.
Mon Jul 02 00:00:00 EDT 2018
Endothelial cells in the innate response to allergens and initiation of atopic asthma.
The Journal of clinical investigation
Asosingh K,Weiss K,Queisser K,Wanner N,Yin M,Aronica M,Erzurum S
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Mon Jul 02 00:00:00 EDT 2018
Defective germline reprogramming rewires the spermatogonial transcriptome.
Nature structural & molecular biology
Vasiliauskaitė L,Berrens RV,Ivanova I,Carrieri C,Reik W,Enright AJ,O'Carroll D
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue May 01 00:00:00 EDT 2018
11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis.
Journal of autoimmunity
Hardy RS,Fenton C,Croft AP,Naylor AJ,Begum R,Desanti G,Buckley CD,Lavery G,Cooper MS,Raza K
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Aug 01 00:00:00 EDT 2018
Inhibition of the JNK/MAPK signaling pathway by myogenesis-associated miRNAs is required for skeletal muscle development.
Cell death and differentiation
Xie SJ,Li JH,Chen HF,Tan YY,Liu SR,Zhang Y,Xu H,Yang JH,Liu S,Zheng LL,Huang MB,Guo YH,Zhang Q,Zhou H,Qu LH
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response.
Cellular and molecular gastroenterology and hepatology
Westendorp BF,Büller NVJA,Karpus ON,van Dop WA,Koster J,Versteeg R,Koelink PJ,Snel CY,Meisner S,Roelofs JJTH,Uhmann A,Ver Loren van Themaat E,Heijmans J,Hahn H,Muncan V,Wildenberg ME,van den Brink GR
11-0451 was used in Flow cytometry/Cell sorting to elucidate the nature of the Indian Hedgehog target cell in the context of intestinal inflammation.
Thu Mar 31 00:00:00 EDT 2022
Shared and independent functions of aPKCλ and Par3 in skin tumorigenesis.
Oncogene
Vorhagen S,Kleefisch D,Persa OD,Graband A,Schwickert A,Saynisch M,Leitges M,Niessen CM,Iden S
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunofluorescence
Sat Sep 01 00:00:00 EDT 2018
VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases.
Glia
Borggrewe M,Grit C,Den Dunnen WFA,Burm SM,Bajramovic JJ,Noelle RJ,Eggen BJL,Laman JD
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2018
A fully-virulent retargeted oncolytic HSV armed with IL-12 elicits local immunity and vaccine therapy towards distant tumors.
PLoS pathogens
Leoni V,Vannini A,Gatta V,Rambaldi J,Sanapo M,Barboni C,Zaghini A,Nanni P,Lollini PL,Casiraghi C,Campadelli-Fiume G
11-0451 was used in Flow cytometry/Cell sorting to analyse the efficacy of a fully-virulent HER2-retargeted oncolytic HSV, demonstrating its ability to elicit a local immune response and systemic therapy vaccine effects.
Wed Aug 01 00:00:00 EDT 2018
Protease-activated receptor-2 signaling through β-arrestin-2 mediates Alternaria alkaline serine protease-induced airway inflammation.
American journal of physiology. Lung cellular and molecular physiology
Yee MC,Nichols HL,Polley D,Saifeddine M,Pal K,Lee K,Wilson EH,Daines MO,Hollenberg MD,Boitano S,DeFea KA
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2018
MyD88 is required for satellite cell-mediated myofiber regeneration in dystrophin-deficient mdx mice.
Human molecular genetics
Gallot YS,Straughn AR,Bohnert KR,Xiong G,Hindi SM,Kumar A
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2018
Isolation of a unique hepatic stellate cell population expressing integrin α8 from embryonic mouse livers.
Developmental dynamics : an official publication of the American Association of Anatomists
Ogawa T,Li Y,Lua I,Hartner A,Asahina K
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunofluorescence
Fri Jun 01 00:00:00 EDT 2018
mTOR Modulates CD8+ T Cell Differentiation in Mice with Invasive Pulmonary Aspergillosis.
Open life sciences
Wang H,Xiao Y,Su L,Cui N,Liu D
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis.
Nature communications
Clemente C,Rius C,Alonso-Herranz L,Martín-Alonso M,Pollán Á,Camafeita E,Martínez F,Mota RA,Núñez V,Rodríguez C,Seiki M,Martínez-González J,Andrés V,Ricote M,Arroyo AG
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Mar 02 00:00:00 EST 2018
In utero electroporation induces cell death and alters embryonic microglia morphology and expression signatures in the developing hypothalamus.
Journal of neuroinflammation
Rosin JM,Kurrasch DM
11-0451 was used in Immunohistochemistry to investigate the effects of in utero electroporation on the microglia in the embryonic brain.
Tue Jun 12 00:00:00 EDT 2018
Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells.
Nature communications
Tosic M,Allen A,Willmann D,Lepper C,Kim J,Duteil D,Schüle R
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
Islr regulates canonical Wnt signaling-mediated skeletal muscle regeneration by stabilizing Dishevelled-2 and preventing autophagy.
Nature communications
Zhang K,Zhang Y,Gu L,Lan M,Liu C,Wang M,Su Y,Ge M,Wang T,Yu Y,Liu C,Li L,Li Q,Zhao Y,Yu Z,Wang F,Li N,Meng Q
11-0451 was used in Flow cytometry/Cell sorting to show that the immunoglobulin superfamily containing leucine-rich repeat stabilises canonical Wnt signalling and promotes skeletal muscle regeneration.
Mon Dec 03 00:00:00 EST 2018
Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice.
Frontiers in immunology
Lainez NM,Jonak CR,Nair MG,Ethell IM,Wilson EH,Carson MJ,Coss D
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Sep 25 00:00:00 EDT 2019
Adipocyte hypertrophy and lipid dynamics underlie mammary gland remodeling after lactation.
Nature communications
Zwick RK,Rudolph MC,Shook BA,Holtrup B,Roth E,Lei V,Van Keymeulen A,Seewaldt V,Kwei S,Wysolmerski J,Rodeheffer MS,Horsley V
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Sep 04 00:00:00 EDT 2018
Simultaneous Inhibition of MEK and Hh Signaling Reduces Pancreatic Cancer Metastasis.
Cancers
Gu D,Lin H,Zhang X,Fan Q,Chen S,Shahda S,Liu Y,Sun J,Xie J
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Fri Oct 26 00:00:00 EDT 2018
Nur77 variants solely comprising the amino-terminal domain activate hypoxia-inducible factor-1α and affect bone marrow homeostasis in mice and humans.
The Journal of biological chemistry
Koenis DS,Medzikovic L,Vos M,Beldman TJ,van Loenen PB,van Tiel CM,Hamers AAJ,Otermin Rubio I,de Waard V,de Vries CJM
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Fri Sep 28 00:00:00 EDT 2018
Nuclear receptor NR2F6 inhibition potentiates responses to PD-L1/PD-1 cancer immune checkpoint blockade.
Nature communications
Klepsch V,Hermann-Kleiter N,Do-Dinh P,Jakic B,Offermann A,Efremova M,Sopper S,Rieder D,Krogsdam A,Gamerith G,Perner S,Tzankov A,Trajanoski Z,Wolf D,Baier G
11-0451 was used in Flow cytometry/Cell sorting to define NR2F6 as an intracellular immune checkpoint with potential as a therapeutic target in cancer treatment.
Wed Apr 18 00:00:00 EDT 2018
ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases.
Frontiers in immunology
Glal D,Sudhakar JN,Lu HH,Liu MC,Chiang HY,Liu YC,Cheng CF,Shui JW
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Sep 26 00:00:00 EDT 2019
Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.
Nature communications
Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Jun 22 00:00:00 EDT 2018
Non-redundant Functions of IL-6 Produced by Macrophages and Dendritic Cells in Allergic Airway Inflammation.
Frontiers in immunology
Gubernatorova EO,Gorshkova EA,Namakanova OA,Zvartsev RV,Hidalgo J,Drutskaya MS,Tumanov AV,Nedospasov SA
11-0451 was used in Flow cytometry/Cell sorting to indicate that IL-6 plays a pathogenic role in the HDM-induced asthma model and that lung macrophages and dendritic cells are the predominant sources of pathogenic IL-6 but contribute differently to the disease.
Wed Oct 02 00:00:00 EDT 2019
Rap1 deficiency-provoked paracrine dysfunction impairs immunosuppressive potency of mesenchymal stem cells in allograft rejection of heart transplantation.
Cell death & disease
Ding Y,Liang X,Zhang Y,Yi L,Shum HC,Chen Q,Chan BP,Fan H,Liu Z,Tergaonkar V,Qi Z,Tse HF,Lian Q
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Mar 07 00:00:00 EST 2018
Partial depletion of CD206-positive M2-like macrophages induces proliferation of beige progenitors and enhances browning after cold stimulation.
Scientific reports
Igarashi Y,Nawaz A,Kado T,Bilal M,Kuwano T,Yamamoto S,Sasahara M,Jiuxiang X,Inujima A,Koizumi K,Imura J,Shibahara N,Usui I,Fujisaka S,Tobe K
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2018
A patient derived xenograft model of cervical cancer and cervical dysplasia.
PloS one
Larmour LI,Cousins FL,Teague JA,Deane JA,Jobling TW,Gargett CE
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunofluorescence
Fri Mar 29 00:00:00 EDT 2019
A patient derived xenograft model of cervical cancer and cervical dysplasia.
PloS one
Larmour LI,Cousins FL,Teague JA,Deane JA,Jobling TW,Gargett CE
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunofluorescence
Fri Mar 29 00:00:00 EDT 2019
CD157 Marks Tissue-Resident Endothelial Stem Cells with Homeostatic and Regenerative Properties.
Cell stem cell
Wakabayashi T,Naito H,Suehiro JI,Lin Y,Kawaji H,Iba T,Kouno T,Ishikawa-Kato S,Furuno M,Takara K,Muramatsu F,Weizhen J,Kidoya H,Ishihara K,Hayashizaki Y,Nishida K,Yoder MC,Takakura N
11-0451-82 was used in Flow cytometry/Cell sorting to show that tissue-resident VESCs display self-renewal capacity and that vascular regeneration potential exists in peripheral blood vessels.
Thu Mar 01 00:00:00 EST 2018
Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation.
Cell
Wang S,Xia P,Chen Y,Qu Y,Xiong Z,Ye B,Du Y,Tian Y,Yin Z,Xu Z,Fan Z
Thu Sep 21 00:00:00 EDT 2017
Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA.
Immunity
Coelho MA,de Carné Trécesson S,Rana S,Zecchin D,Moore C,Molina-Arcas M,East P,Spencer-Dene B,Nye E,Barnouin K,Snijders AP,Lai WS,Blackshear PJ,Downward J
11-0451-82 was used in Flow Cytometry to demonstrate that RAS can drive cell-intrinsic PD-L1 expression, thus presenting therapeutic opportunities to reverse the innately immunoresistant phenotype of RAS mutant cancers.
Tue Dec 19 00:00:00 EST 2017
Differential cytokine contributions of perivascular haematopoietic stem cell niches.
Nature cell biology
Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Adipocyte Accumulation in the Bone Marrow during Obesity and Aging Impairs Stem Cell-Based Hematopoietic and Bone Regeneration.
Cell stem cell
Ambrosi TH,Scialdone A,Graja A,Gohlke S,Jank AM,Bocian C,Woelk L,Fan H,Logan DW,Schürmann A,Saraiva LR,Schulz TJ
11-0451 was used in Flow cytometry/Cell sorting to specify the cellular identities of the adipogenic and osteogenic lineages of the bone.
Thu Jun 01 00:00:00 EDT 2017
Dectin-2 Deficiency Modulates Th1 Differentiation and Improves Wound Healing After Myocardial Infarction.
Circulation research
Yan X,Zhang H,Fan Q,Hu J,Tao R,Chen Q,Iwakura Y,Shen W,Lu L,Zhang Q,Zhang R
11-0451 was used in Flow cytometry/Cell sorting to determine whether Dectin-2 signalling is involved in the healing process and cardiac remodelling after myocardial infarction and to elucidate the underlying molecular mechanisms.
Fri Mar 31 00:00:00 EDT 2017
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
The Journal of clinical investigation
Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Preexisting endothelial cells mediate cardiac neovascularization after injury.
The Journal of clinical investigation
He L,Huang X,Kanisicak O,Li Y,Wang Y,Li Y,Pu W,Liu Q,Zhang H,Tian X,Zhao H,Liu X,Zhang S,Nie Y,Hu S,Miao X,Wang QD,Wang F,Chen T,Xu Q,Lui KO,Molkentin JD,Zhou B
11-0451 was used in Flow cytometry/Cell sorting to indicate that therapeutic strategies for inducing neovascularization should not be based on targeting presumptive lineage transdifferentiation.
Tue Aug 01 00:00:00 EDT 2017
Sphingosine Kinase 2 Deficiency Attenuates Kidney Fibrosis via IFN-γ.
Journal of the American Society of Nephrology : JASN
Bajwa A,Huang L,Kurmaeva E,Ye H,Dondeti KR,Chroscicki P,Foley LS,Balogun ZA,Alexander KJ,Park H,Lynch KR,Rosin DL,Okusa MD
Sat Apr 01 00:00:00 EDT 2017
Anti-CD137 Suppresses Tumor Growth by Blocking Reverse Signaling by CD137 Ligand.
Cancer research
Kang SW,Lee SC,Park SH,Kim J,Kim HH,Lee HW,Seo SK,Kwon BS,Cho HR,Kwon B
11-0451-82 was used in Flow Cytometry to report findings related to reverse signaling by CD137 ligand (CD137L) in antigen-presenting dendritic cells (DC) in tumors that address these paradoxical results.
Wed Nov 01 00:00:00 EDT 2017
Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination.
Cancer research
Jiang H,Rivera-Molina Y,Gomez-Manzano C,Clise-Dwyer K,Bover L,Vence LM,Yuan Y,Lang FF,Toniatti C,Hossain MB,Fueyo J
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sat Jul 15 00:00:00 EDT 2017
Virus-induced inflammasome activation is suppressed by prostaglandin D2/DP1 signaling.
Proceedings of the National Academy of Sciences of the United States of America
Vijay R,Fehr AR,Janowski AM,Athmer J,Wheeler DL,Grunewald M,Sompallae R,Kurup SP,Meyerholz DK,Sutterwala FS,Narumiya S,Perlman S
11-0451 was used in Flow cytometry/Cell sorting to study the role of Prostaglandin D2 signalling in optimal microglia/macrophage activation and interferon expression after infection with a neurotropic coronavirus.
Mon Jul 03 00:00:00 EDT 2017
Sigma-1 receptors control immune-driven peripheral opioid analgesia during inflammation in mice.
Proceedings of the National Academy of Sciences of the United States of America
Tejada MA,Montilla-García A,Cronin SJ,Cikes D,Sánchez-Fernández C,González-Cano R,Ruiz-Cantero MC,Penninger JM,Vela JM,Baeyens JM,Cobos EJ
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2017
FXYD5 Is an Essential Mediator of the Inflammatory Response during Lung Injury.
Frontiers in immunology
Brazee PL,Soni PN,Tokhtaeva E,Magnani N,Yemelyanov A,Perlman HR,Ridge KM,Sznajder JI,Vagin O,Dada LA
11-0451 was used in Flow cytometry/Cell sorting to confirm that FXYD5 induces a range of pro-inflammatory effects.
Fri Mar 18 00:00:00 EDT 2022
Inhibition of the NOD-Like Receptor Protein 3 Inflammasome Is Protective in Juvenile Influenza A Virus Infection.
Frontiers in immunology
Coates BM,Staricha KL,Ravindran N,Koch CM,Cheng Y,Davis JM,Shumaker DK,Ridge KM
11-0451 was used in Flow cytometry/Cell sorting to demonstrate that during Influenza A Virus infection, inhibition of the NOD-like receptor protein 3 inflammasome was successful in alleviating damage to lung tissues, usually caused by the host immune response to the virus.
Mon Apr 25 00:00:00 EDT 2022
Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity.
Breast cancer research : BCR
Chamberlin T,D'Amato JV,Arendt LM
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Nov 29 00:00:00 EST 2017
Ablation of Pericyte-Like Cells in Lungs by Oropharyngeal Aspiration of Diphtheria Toxin.
American journal of respiratory cell and molecular biology
Hung CF,Chow YH,Liles WC,Altemeier WA,Schnapp LM
11-0451 was used in Flow cytometry/Cell sorting to demonstrate the feasibility of administering diphtheria toxin by oropharyngeal aspiration as an approach to ablating FoxD1-derived cells.
Wed Feb 01 00:00:00 EST 2017
Depletion of microglia exacerbates postischemic inflammation and brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Jin WN,Shi SX,Li Z,Li M,Wood K,Gonzales RJ,Liu Q
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
An atypical role for the myeloid receptor Mincle in central nervous system injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Arumugam TV,Manzanero S,Furtado M,Biggins PJ,Hsieh YH,Gelderblom M,MacDonald KP,Salimova E,Li YI,Korn O,Dewar D,Macrae IM,Ashman RB,Tang SC,Rosenthal NA,Ruitenberg MJ,Magnus T,Wells CA
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
Inflammatory stimuli induce acyl-CoA thioesterase 7 and remodeling of phospholipids containing unsaturated long (≥C20)-acyl chains in macrophages.
Journal of lipid research
Wall VZ,Barnhart S,Kramer F,Kanter JE,Vivekanandan-Giri A,Pennathur S,Bolego C,Ellis JM,Gijón MA,Wolfgang MJ,Bornfeldt KE
11-0451 was used in Flow cytometry/Cell sorting to investigate the downstream effects of lipopolysaccharide-induced induction of acyl-CoA thioesterase 7, and its role in inflammatory settings in myeloid cells.
Thu Jun 01 00:00:00 EDT 2017
Tumor Necrosis Factor Alpha-Induced Recruitment of Inflammatory Mononuclear Cells Leads to Inflammation and Altered Brain Development in Murine Cytomegalovirus-Infected Newborn Mice.
Journal of virology
Seleme MC,Kosmac K,Jonjic S,Britt WJ
11-0451 was used in Flow cytometry/Cell sorting to show that during cytomegalovirus (HCMV) infection in infants, tumor necrosis factor alpha plays a key role in brain inflammation and abnormal neurodevelopment. Targeting TNF-α with neutralising antibodies normalized neurodevelopment in infant mice.
Sat Apr 15 00:00:00 EDT 2017
Increased White Matter Inflammation in Aging- and Alzheimer's Disease Brain.
Frontiers in molecular neuroscience
Raj D,Yin Z,Breur M,Doorduin J,Holtman IR,Olah M,Mantingh-Otter IJ,Van Dam D,De Deyn PP,den Dunnen W,Eggen BJL,Amor S,Boddeke E
11-0451 was used in Flow cytometry/Cell sorting to indicate that microglia-induced neuroinflammation is predominant in the white matter of aging mice and humans as well as in EOAD brains.
Thu Oct 01 00:00:00 EDT 2020
Role of Triggering Receptor Expressed on Myeloid Cell-1 Expression in Mammalian Target of Rapamycin Modulation of CD8+ T-cell Differentiation during the Immune Response to Invasive Pulmonary Aspergillosis.
Chinese medical journal
Cui N,Wang H,Su LX,Zhang JH,Long Y,Liu DW
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sat May 20 00:00:00 EDT 2017
Cornea lymphatics drive the CD8+ T-cell response to herpes simplex virus-1.
Immunology and cell biology
Gurung HR,Carr MM,Carr DJ
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
Dimethyl fumarate treatment after traumatic brain injury prevents depletion of antioxidative brain glutathione and confers neuroprotection.
Journal of neurochemistry
Krämer T,Grob T,Menzel L,Hirnet T,Griemert E,Radyushkin K,Thal SC,Methner A,Schaefer MKE
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Fri Dec 01 00:00:00 EST 2017
IL-6 Regulates M2 Polarization and Local Proliferation of Adipose Tissue Macrophages in Obesity.
Journal of immunology (Baltimore, Md. : 1950)
Braune J,Weyer U,Hobusch C,Mauer J,Brüning JC,Bechmann I,Gericke M
11-0451 was used in Flow cytometry/Cell sorting to study how IL-6 acts as a Th2 cytokine in obesity by stimulating M2 polarisation and local adipose tissue macrophages proliferation.
Sat Apr 01 00:00:00 EDT 2017
Cytochrome P450 26A1 modulates natural killer cells in mouse early pregnancy.
Journal of cellular and molecular medicine
Meng CY,Li ZY,Fang WN,Song ZH,Yang DD,Li DD,Yang Y,Peng JP
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
β3-Adrenergic Regulation of EPC Features Through Manipulation of the Bone Marrow MSC Niche.
Journal of cellular biochemistry
Vafaei R,Nassiri SM,Siavashi V
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2017
The common parasite Toxoplasma gondii induces prostatic inflammation and microglandular hyperplasia in a mouse model.
The Prostate
Colinot DL,Garbuz T,Bosland MC,Wang L,Rice SE,Sullivan WJ,Arrizabalaga G,Jerde TJ
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sat Jul 01 00:00:00 EDT 2017
Role of Prolactin in Promotion of Immune Cell Migration into the Mammary Gland.
Journal of mammary gland biology and neoplasia
Dill R,Walker AM
11-0451 was used in Flow cytometry/Cell sorting to investigate the role of prolactin in immune cell recruitment.
Wed Mar 01 00:00:00 EST 2017
Reduced Expression of VAMP8 in Lacrimal Gland Affected by Chronic Graft-versus-Host Disease.
Journal of ophthalmology
Fukui M,Ogawa Y,Mukai S,Kamoi M,Asato T,Kawakami Y,Tsubota K
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunofluorescence
Thu Mar 10 00:00:00 EST 2022
Protein Tyrosine Phosphatase Inhibition Prevents Experimental Cerebral Malaria by Precluding CXCR3 Expression on T Cells.
Scientific reports
Van Den Ham KM,Smith LK,Richer MJ,Olivier M
11-0451 was used in Flow cytometry/Cell sorting to demonstrate that inhibition of protein tyrosine phosphatase activity significantly attenuates T cell sequestration within the brain and prevents the development of neuropathology.
Fri Jul 14 00:00:00 EDT 2017
Herpes simplex virus-1 infects the olfactory bulb shortly following ocular infection and exhibits a long-term inflammatory profile in the form of effector and HSV-1-specific T cells.
Journal of neuroinflammation
Menendez CM,Carr DJJ
11-0451 was used in Flow cytometry/Cell sorting to characterise the capacity of Herpes simplex virus 1 to establish latency within olfactory bulb tissue and profile the local T lymphocyte response.
Fri Jun 23 00:00:00 EDT 2017
The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration.
eLife
Xiong G,Hindi SM,Mann AK,Gallot YS,Bohnert KR,Cavener DR,Whittemore SR,Kumar A
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Mar 23 00:00:00 EDT 2017
microRNA-449a modulates medullary thymic epithelial cell differentiation.
Scientific reports
Chen P,Zhang H,Sun X,Hu Y,Jiang W,Liu Z,Liu S,Zhang X
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Nov 21 00:00:00 EST 2017
Tristetraprolin expression by keratinocytes controls local and systemic inflammation.
JCI insight
Andrianne M,Assabban A,La C,Mogilenko D,Salle DS,Fleury S,Doumont G,Van Simaeys G,Nedospasov SA,Blackshear PJ,Dombrowicz D,Goriely S,Van Maele L
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Jun 02 00:00:00 EDT 2017
The Interleukin (IL)-1R1 pathway is a critical negative regulator of PyMT-mediated mammary tumorigenesis and pulmonary metastasis.
Oncoimmunology
Dagenais M,Dupaul-Chicoine J,Douglas T,Champagne C,Morizot A,Saleh M
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB.
PloS one
Gao SY,Zheng GS,Wang L,Liang YJ,Zhang SE,Lao XM,Li K,Liao GQ
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Sep 18 00:00:00 EDT 2017
Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces.
JCI insight
Azzam KM,Madenspacher JH,Cain DW,Lai L,Gowdy KM,Rai P,Janardhan K,Clayton N,Cunningham W,Jensen H,Patel PS,Kearney JF,Taylor GA,Fessler MB
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Aug 17 00:00:00 EDT 2017
Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis.
Stem cell reports
Redgrave RE,Tual-Chalot S,Davison BJ,Singh E,Hall D,Amirrasouli MM,Gilchrist D,Medvinsky A,Arthur HM
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue May 09 00:00:00 EDT 2017
Heavy Chain-Hyaluronan/Pentraxin 3 from Amniotic Membrane Suppresses Inflammation and Scarring in Murine Lacrimal Gland and Conjunctiva of Chronic Graft-versus-Host Disease.
Scientific reports
Ogawa Y,He H,Mukai S,Imada T,Nakamura S,Su CW,Mahabole M,Tseng SC,Tsubota K
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Mon Feb 06 00:00:00 EST 2017
The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity.
Cell
Moroishi T,Hayashi T,Pan WW,Fujita Y,Holt MV,Qin J,Carson DA,Guan KL
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunofluorescence
Thu Dec 01 00:00:00 EST 2016
Classical dendritic cells are required for dietary antigen-mediated induction of peripheral T(reg) cells and tolerance.
Nature immunology
Esterházy D,Loschko J,London M,Jove V,Oliveira TY,Mucida D
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2016
Macrophage autophagy limits acute toxic liver injury in mice through down regulation of interleukin-1β.
Journal of hepatology
Ilyas G,Zhao E,Liu K,Lin Y,Tesfa L,Tanaka KE,Czaja MJ
11-0451 was used in Flow cytometry/Cell sorting to show that macrophage autophagy functions to limit acute toxin-induced liver injury and death by inhibiting the generation of inflammasome-dependent IL-1β.
Fri Jan 01 00:00:00 EST 2016
Oligodendrocyte death results in immune-mediated CNS demyelination.
Nature neuroscience
Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Non-Cell-Autonomous Regulation of Prostate Epithelial Homeostasis by Androgen Receptor.
Molecular cell
Zhang B,Kwon OJ,Henry G,Malewska A,Wei X,Zhang L,Brinkley W,Zhang Y,Castro PD,Titus M,Chen R,Sayeeduddin M,Raj GV,Mauck R,Roehrborn C,Creighton CJ,Strand DW,Ittmann MM,Xin L
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Sep 15 00:00:00 EDT 2016
Endothelin A receptor activation on mesangial cells initiates Alport glomerular disease.
Kidney international
Dufek B,Meehan DT,Delimont D,Cheung L,Gratton MA,Phillips G,Song W,Liu S,Cosgrove D
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunofluorescence
Mon Aug 01 00:00:00 EDT 2016
Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification.
Annals of surgery
Loder S,Agarwal S,Sorkin M,Breuler C,Li J,Peterson J,Gardenier J,Hsieh HH,Wang SC,Mehrara BJ,Levi B
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
Mesenchymal stromal cell-derived extracellular vesicles rescue radiation damage to murine marrow hematopoietic cells.
Leukemia
Wen S,Dooner M,Cheng Y,Papa E,Del Tatto M,Pereira M,Deng Y,Goldberg L,Aliotta J,Chatterjee D,Stewart C,Carpanetto A,Collino F,Bruno S,Camussi G,Quesenberry P
11045182 was used in flow cytometry to examine the effects of mesenchymal stromal cell-derived extracellular vesicles on bone marrow radiation damage
Tue Nov 01 00:00:00 EDT 2016
IL-33 ameliorates Alzheimer's disease-like pathology and cognitive decline.
Proceedings of the National Academy of Sciences of the United States of America
Fu AK,Hung KW,Yuen MY,Zhou X,Mak DS,Chan IC,Cheung TH,Zhang B,Fu WY,Liew FY,Ip NY
11-0451 was used in Flow cytometry/Cell sorting to investigate the role of IL-33/ST2 signalling in the pathogenesis of Alzheimer's disease, showing that treatment with IL-33 ameliorates Alzheimer's disease-like pathology and cognitive decline.
Tue May 10 00:00:00 EDT 2016
Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America
Nishio M,Sugimachi K,Goto H,Wang J,Morikawa T,Miyachi Y,Takano Y,Hikasa H,Itoh T,Suzuki SO,Kurihara H,Aishima S,Leask A,Sasaki T,Nakano T,Nishina H,Nishikawa Y,Sekido Y,Nakao K,Shin-Ya K,Mimori K,Suzuki A
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunofluorescence
Tue Jan 05 00:00:00 EST 2016
Overexpression of PIK3CA in murine head and neck epithelium drives tumor invasion and metastasis through PDK1 and enhanced TGFβ signaling.
Oncogene
Du L,Chen X,Cao Y,Lu L,Zhang F,Bornstein S,Li Y,Owens P,Malkoski S,Said S,Jin F,Kulesz-Martin M,Gross N,Wang XJ,Lu SL
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Thu Sep 01 00:00:00 EDT 2016
Metabolic reprogramming through fatty acid transport protein 1 (FATP1) regulates macrophage inflammatory potential and adipose inflammation.
Molecular metabolism
Johnson AR,Qin Y,Cozzo AJ,Freemerman AJ,Huang MJ,Zhao L,Sampey BP,Milner JJ,Beck MA,Damania B,Rashid N,Galanko JA,Lee DP,Edin ML,Zeldin DC,Fueger PT,Dietz B,Stahl A,Wu Y,Mohlke KL,Makowski L
11-0451 was used in Flow cytometry/Cell sorting to outline a novel mechanism for regulating adipose tissue homoeostasis and inflammation through metabolic reprogramming of macrophages; directed by fatty acid transport protein 1.
Fri Jul 01 00:00:00 EDT 2016
Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification.
Stem cells (Dayton, Ohio)
Agarwal S,Loder SJ,Sorkin M,Li S,Shrestha S,Zhao B,Mishina Y,James AW,Levi B
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification.
Stem cells (Dayton, Ohio)
Agarwal S,Loder SJ,Sorkin M,Li S,Shrestha S,Zhao B,Mishina Y,James AW,Levi B
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Aug 15 00:00:00 EDT 2016
Mucosal Langerhans Cells Promote Differentiation of Th17 Cells in a Murine Model of Periodontitis but Are Not Required for Porphyromonas gingivalis-Driven Alveolar Bone Destruction.
Journal of immunology (Baltimore, Md. : 1950)
Bittner-Eddy PD,Fischer LA,Kaplan DH,Thieu K,Costalonga M
11-0451 was used in Flow cytometry/Cell sorting to indicate that both Langerhans cells and Th17 cells are redundant in contributing to alveolar bone destruction in a murine model of periodontitis.
Mon Aug 15 00:00:00 EDT 2016
Macrophage migration inhibitory factor promotes cardiac stem cell proliferation and endothelial differentiation through the activation of the PI3K/Akt/mTOR and AMPK pathways.
International journal of molecular medicine
Cui J,Zhang F,Wang Y,Liu J,Ming X,Hou J,Lv B,Fang S,Yu B
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2016
ECM-Dependence of Endothelial Progenitor Cell Features.
Journal of cellular biochemistry
Siavashi V,Nassiri SM,Rahbarghazi R,Vafaei R,Sariri R
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Effects of nerve growth factor and basic fibroblast growth factor dual gene modification on rat bone marrow mesenchymal stem cell differentiation into neuron-like cells in vitro.
Molecular medicine reports
Hu Y,Zhang Y,Tian K,Xun C,Wang S,Lv D
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
A flow cytometric approach to analyzing mature and progenitor endothelial cells following traumatic brain injury.
Journal of neuroscience methods
Assis-Nascimento P,Umland O,Cepero ML,Liebl DJ
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2016
Treatment of radiation-induced acute intestinal injury with bone marrow-derived mesenchymal stem cells.
Experimental and therapeutic medicine
Zheng K,Wu W,Yang S,Huang L,Chen J,Gong C,Fu Z,Lin R,Tan J
11-0451 was used in Flow cytometry/Cell sorting to identify bone marrow-derived mesenchymal stem cells, whose reparative function can be used to treat radiation-induced acute intestinal injury.
Wed Jun 01 00:00:00 EDT 2016
Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development.
Cell reports
Barrett NA,Malouf C,Kapeni C,Bacon WA,Giotopoulos G,Jacobsen SEW,Huntly BJ,Ottersbach K
11-0451 was used in Flow cytometry/Cell sorting to elucidate the contribution of MII-AF4 in B cell acute lymphoblastic leukaemia early development in the mouse embryo.
Tue Jul 26 00:00:00 EDT 2016
A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.
Nature communications
Jeric I,Maurer G,Cavallo AL,Raguz J,Desideri E,Tarkowski B,Parrini M,Fischer I,Zatloukal K,Baccarini M
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Dec 21 00:00:00 EST 2016
Selective Expression of Osteopontin in ALS-resistant Motor Neurons is a Critical Determinant of Late Phase Neurodegeneration Mediated by Matrix Metalloproteinase-9.
Scientific reports
Morisaki Y,Niikura M,Watanabe M,Onishi K,Tanabe S,Moriwaki Y,Okuda T,Ohara S,Murayama S,Takao M,Uchida S,Yamanaka K,Misawa H
11-0451 was used in Immunohistochemistry to report that the extracellular matrix (ECM) protein osteopontin (OPN) is selectively expressed by FR and S MNs and ALS-resistant motor pools, whereas matrix metalloproteinase-9 (MMP-9) is selectively expressed by FF MNs.
Mon Jun 06 00:00:00 EDT 2016
Laminin regulates PDGFRβ(+) cell stemness and muscle development.
Nature communications
Yao Y,Norris EH,Mason CE,Strickland S
11-0451 was used in Flow cytometry/Cell sorting to show that laminin has a critical role in the control of PDGFRBeta(+) cell stemness and that PDGFRBeta(+) may be a drug target for treatment of muscular dystrophy.
Tue May 03 00:00:00 EDT 2016
Regulation of Prostate Development and Benign Prostatic Hyperplasia by Autocrine Cholinergic Signaling via Maintaining the Epithelial Progenitor Cells in Proliferating Status.
Stem cell reports
Wang N,Dong BJ,Quan Y,Chen Q,Chu M,Xu J,Xue W,Huang YR,Yang R,Gao WQ
11-0451 was used in Flow cytometry/Cell sorting to investigate the role of autocrine cholinergic signaling (ASC) in prostate development, showing that development is regulated by ASC.
Tue May 10 00:00:00 EDT 2016
Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney.
JCI insight
Sato Y,Mii A,Hamazaki Y,Fujita H,Nakata H,Masuda K,Nishiyama S,Shibuya S,Haga H,Ogawa O,Shimizu A,Narumiya S,Kaisho T,Arita M,Yanagisawa M,Miyasaka M,Sharma K,Minato N,Kawamoto H,Yanagita M
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Thu Jul 21 00:00:00 EDT 2016
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
Nature communications
Ruhland MK,Loza AJ,Capietto AH,Luo X,Knolhoff BL,Flanagan KC,Belt BA,Alspach E,Leahy K,Luo J,Schaffer A,Edwards JR,Longmore G,Faccio R,DeNardo DG,Stewart SA
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Jun 08 00:00:00 EDT 2016
SCIB1, a huIgG1 antibody DNA vaccination, combined with PD-1 blockade induced efficient therapy of poorly immunogenic tumors.
Oncotarget
Xue W,Brentville VA,Symonds P,Cook KW,Yagita H,Metheringham RL,Durrant LG
11-0451 was used in Flow cytometry/Cell sorting to investigate the anti-tumour effect of a huIgG1 antibody DNA vaccine and PD-1 blockade.
Tue Dec 13 00:00:00 EST 2016
Targeting VEGF-A in myeloid cells enhances natural killer cell responses to chemotherapy and ameliorates cachexia.
Nature communications
Klose R,Krzywinska E,Castells M,Gotthardt D,Putz EM,Kantari-Mimoun C,Chikdene N,Meinecke AK,Schrödter K,Helfrich I,Fandrey J,Sexl V,Stockmann C
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Aug 19 00:00:00 EDT 2016
Protein Kinase D2 Protects against Acute Colitis Induced by Dextran Sulfate Sodium in Mice.
Scientific reports
Xiong J,Zhou MF,Wang YD,Chen LP,Xu WF,Wang YD,Deng F,Liu SD
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Sep 23 00:00:00 EDT 2016
Absence of apolipoprotein E protects mice from cerebral malaria.
Scientific reports
Kassa FA,Van Den Ham K,Rainone A,Fournier S,Boilard E,Olivier M
11-0451 was used in Flow cytometry/Cell sorting to reveal a unique biomarker, apolipoprotein E, for cerebral malaria.
Tue Sep 20 00:00:00 EDT 2016
Preparation of Single Cell Suspensions from Mouse Aorta.
Bio-protocol
Hu D,Yin C,Mohanta SK,Weber C,Habenicht AJ
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sun Jun 05 00:00:00 EDT 2016
Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma.
Oncoimmunology
Vandenberk L,Garg AD,Verschuere T,Koks C,Belmans J,Beullens M,Agostinis P,De Vleeschouwer S,Van Gool SW
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2016
Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.
Scientific reports
Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Jun 15 00:00:00 EDT 2016
LTβR controls thymic portal endothelial cells for haematopoietic progenitor cell homing and T-cell regeneration.
Nature communications
Shi Y,Wu W,Chai Q,Li Q,Hou Y,Xia H,Ren B,Xu H,Guo X,Jin C,Lv M,Wang Z,Fu YX,Zhu M
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Aug 05 00:00:00 EDT 2016
Structural and functional features of central nervous system lymphatic vessels.
Nature
Louveau A,Smirnov I,Keyes TJ,Eccles JD,Rouhani SJ,Peske JD,Derecki NC,Castle D,Mandell JW,Lee KS,Harris TH,Kipnis J
11-0451 was used in Immunofluorescence to investigate the mechanisms governing the entrance and exit of immune cells from the CNS.
Thu Jul 16 00:00:00 EDT 2015
Parent stem cells can serve as niches for their daughter cells.
Nature
Pardo-Saganta A,Tata PR,Law BM,Saez B,Chow RD,Prabhu M,Gridley T,Rajagopal J
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunofluorescence
Thu Jul 30 00:00:00 EDT 2015
Host microbiota constantly control maturation and function of microglia in the CNS.
Nature neuroscience
Erny D,Hrabě de Angelis AL,Jaitin D,Wieghofer P,Staszewski O,David E,Keren-Shaul H,Mahlakoiv T,Jakobshagen K,Buch T,Schwierzeck V,Utermöhlen O,Chun E,Garrett WS,McCoy KD,Diefenbach A,Staeheli P,Stecher B,Amit I,Prinz M
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells.
The Journal of clinical investigation
Gori JL,Butler JM,Chan YY,Chandrasekaran D,Poulos MG,Ginsberg M,Nolan DJ,Elemento O,Wood BL,Adair JE,Rafii S,Kiem HP
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2015
Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus.
EMBO molecular medicine
Herbst S,Shah A,Mazon Moya M,Marzola V,Jensen B,Reed A,Birrell MA,Saijo S,Mostowy S,Shaunak S,Armstrong-James D
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2015
Tracking and Functional Characterization of Epithelial-Mesenchymal Transition and Mesenchymal Tumor Cells during Prostate Cancer Metastasis.
Cancer research
Ruscetti M,Quach B,Dadashian EL,Mulholland DJ,Wu H
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
Atypical chemokine receptor 1 deficiency reduces atherogenesis in ApoE-knockout mice.
Cardiovascular research
Wan W,Liu Q,Lionakis MS,Marino AP,Anderson SA,Swamydas M,Murphy PM
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
Brahma is required for cell cycle arrest and late muscle gene expression during skeletal myogenesis.
EMBO reports
Albini S,Coutinho Toto P,Dall'Agnese A,Malecova B,Cenciarelli C,Felsani A,Caruso M,Bultman SJ,Puri PL
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunofluorescence
Sat Aug 01 00:00:00 EDT 2015
The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma.
eLife
Krah NM,De La O JP,Swift GH,Hoang CQ,Willet SG,Chen Pan F,Cash GM,Bronner MP,Wright CV,MacDonald RJ,Murtaugh LC
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunofluorescence
Tue Jul 07 00:00:00 EDT 2015
Identification of a chronic non-neurodegenerative microglia activation state in a mouse model of peroxisomal β-oxidation deficiency.
Glia
Verheijden S,Beckers L,Casazza A,Butovsky O,Mazzone M,Baes M
11-0451-82 was used in Flow Cytometry to demonstrate that chronic activation of resident microglia does not necessarily lead to phagocytosis nor overt neurotoxicity.
Tue Sep 01 00:00:00 EDT 2015
Impaired gp100-Specific CD8(+) T-Cell Responses in the Presence of Myeloid-Derived Suppressor Cells in a Spontaneous Mouse Melanoma Model.
The Journal of investigative dermatology
Mairhofer DG,Ortner D,Tripp CH,Schaffenrath S,Fleming V,Heger L,Komenda K,Reider D,Dudziak D,Chen S,Becker JC,Flacher V,Stoitzner P
11-0451 was used in Flow cytometry/Cell sorting to characterise the immune status and functional properties of immune cells in a spontaneous melanoma mouse model.
Sun Nov 01 00:00:00 EDT 2015
Transcriptional Pathways in cPGI2-Induced Adipocyte Progenitor Activation for Browning.
Frontiers in endocrinology
Bayindir I,Babaeikelishomi R,Kocanova S,Sousa IS,Lerch S,Hardt O,Wild S,Bosio A,Bystricky K,Herzig S,Vegiopoulos A
11-0451 was used in Flow cytometry/Cell sorting to develop models for the mechanistic investigation of progenitor-mediated beige/brite adipocyte differentiation.
Tue Sep 08 00:00:00 EDT 2015
Experimental design of complement component 5a-induced acute lung injury (C5a-ALI): a role of CC-chemokine receptor type 5 during immune activation by anaphylatoxin.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Russkamp NF,Ruemmler R,Roewe J,Moore BB,Ward PA,Bosmann M
11-0451 was used in Flow cytometry/Cell sorting to determine that the detrimental effects of C5a are partly mediated through CCR5 activation downstream of C5aR1.
Tue Sep 01 00:00:00 EDT 2015
Cartilage stem/progenitor cells are activated in osteoarthritis via interleukin-1β/nerve growth factor signaling.
Arthritis research & therapy
Jiang Y,Hu C,Yu S,Yan J,Peng H,Ouyang HW,Tuan RS
11-0451 was used in Flow cytometry/Cell sorting to elucidate the cellular and molecular interactions between interleukin-1β and nerve growth factor in articular cartilage and osteoarthritis.
Tue Nov 17 00:00:00 EST 2015
Myeloid Cell-Restricted Insulin/IGF-1 Receptor Deficiency Protects against Skin Inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Knuever J,Willenborg S,Ding X,Akyüz MD,Partridge L,Niessen CM,Brüning JC,Eming SA
11-0451 was used in Flow cytometry/Cell sorting to provide evidence for a proinflammatory IR/IGF-1R-dependent pathway in myeloid cells which may be useful in the treatment against DM.
Tue Dec 01 00:00:00 EST 2015
Mouse bone marrow-derived mesenchymal stem cells inhibit leukemia/lymphoma cell proliferation in vitro and in a mouse model of allogeneic bone marrow transplant.
International journal of molecular medicine
Song N,Gao L,Qiu H,Huang C,Cheng H,Zhou H,Lv S,Chen L,Wang J
11-0451 was used in Flow cytometry/Cell sorting to determine that MSCs may be safe and effective when used in allogeneic BMT for the treatment of haemotological malignancies.
Wed Jul 01 00:00:00 EDT 2015
Multi-Drug Resistance ABC Transporter Inhibition Enhances Murine Ventral Prostate Stem/Progenitor Cell Differentiation.
Stem cells and development
Samant MD,Jackson CM,Felix CL,Jones AJ,Goodrich DW,Foster BA,Huss WJ
11-0451 was used in Flow cytometry/Cell sorting to investigate the role of MDR-ABC efflux transporters in prostate differentiation and epithelium regeneration in the murine prostate.
Fri May 15 00:00:00 EDT 2015
Mouse dental pulp stem cells support human umbilical cord blood-derived hematopoietic stem/progenitor cells in vitro.
Cell transplantation
Nakatsuka R,Matsuoka Y,Uemura Y,Sumide K,Iwaki R,Takahashi M,Fujioka T,Sasaki Y,Sonoda Y
11-0451 was used in Flow cytometry/Cell sorting to demonstrate that prospectively isolated murine PDGFRα and Sca-1 double-positive dental pulp stem cells could support primitive human CD34+ and CD34- hematopoietic stem cells in vitro.
Wed Sep 16 00:00:00 EDT 2015
Conditional immortalization of primary adipocyte precursor cells.
Adipocyte
Church C,Brown M,Rodeheffer MS
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Aug 10 00:00:00 EDT 2015
Nonadherent culture method downregulates stem cell antigen-1 expression in mouse bone marrow mesenchymal stem cells.
Experimental and therapeutic medicine
Deng B,Deng W,Xiao P,Zeng K,Zhang S,Zhang H,Deng DY,Yang Y
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.
PloS one
Tähtinen S,Kaikkonen S,Merisalo-Soikkeli M,Grönberg-Vähä-Koskela S,Kanerva A,Parviainen S,Vähä-Koskela M,Hemminki A
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Apr 28 00:00:00 EDT 2016
Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury.
Nature communications
Ito M,Shichita T,Okada M,Komine R,Noguchi Y,Yoshimura A,Morita R
11-0451 was used in Flow cytometry/Cell sorting to report that Bruton's tyrosine kinase (BTK) is an essential component of the NLRP3 inflammasome, in which BTK physically interacts with ASC and NLRP3.
Wed Jun 10 00:00:00 EDT 2015
Distinct in vitro properties of embryonic and extraembryonic fibroblast-like cells are reflected in their in vivo behavior following grafting in the adult mouse brain.
Cell transplantation
Costa R,Bergwerf I,Santermans E,De Vocht N,Praet J,Daans J,Le Blon D,Hoornaert C,Reekmans K,Hens N,Goossens H,Berneman Z,Parolini O,Alviano F,Ponsaerts P
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Nov 16 00:00:00 EST 2015
Distinct in vitro properties of embryonic and extraembryonic fibroblast-like cells are reflected in their in vivo behavior following grafting in the adult mouse brain.
Cell transplantation
Costa R,Bergwerf I,Santermans E,De Vocht N,Praet J,Daans J,Le Blon D,Hoornaert C,Reekmans K,Hens N,Goossens H,Berneman Z,Parolini O,Alviano F,Ponsaerts P
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Nov 16 00:00:00 EST 2015
The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance.
Cell reports
Hermann-Kleiter N,Klepsch V,Wallner S,Siegmund K,Klepsch S,Tuzlak S,Villunger A,Kaminski S,Pfeifhofer-Obermair C,Gruber T,Wolf D,Baier G
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2015
Tissues from equine cadaver ligaments up to 72 hours of post-mortem: a promising reservoir of stem cells.
Stem cell research & therapy
Shikh Alsook MK,Gabriel A,Piret J,Waroux O,Tonus C,Connan D,Baise E,Antoine N
11-0451-82 was used in Flow cytometry/Cell sorting to examine how long equine mesenchymal stem cells can survive post-mortem, assessing their proliferative ability and ability to remain undifferentiated.
Fri Dec 18 00:00:00 EST 2015
Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.
PloS one
Szulzewsky F,Pelz A,Feng X,Synowitz M,Markovic D,Langmann T,Holtman IR,Wang X,Eggen BJ,Boddeke HW,Hambardzumyan D,Wolf SA,Kettenmann H
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2016
Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts.
Stem cell reports
Neri T,Muggeo S,Paulis M,Caldana ME,Crisafulli L,Strina D,Focarelli ML,Faggioli F,Recordati C,Scaramuzza S,Scanziani E,Mantero S,Buracchi C,Sobacchi C,Lombardo A,Naldini L,Vezzoni P,Villa A,Ficara F
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Oct 13 00:00:00 EDT 2015
Iron prevents the development of experimental cerebral malaria by attenuating CXCR3-mediated T cell chemotaxis.
PloS one
Van Den Ham KM,Shio MT,Rainone A,Fournier S,Krawczyk CM,Olivier M
11-0451 was used in Flow cytometry/Cell sorting to study the effect of iron in attenuating CXCR3-mediated T cell chemotaxis and migration to the brain and therefore inhibiting Experimental Cerebral Malaria pathology.
Thu Jan 21 00:00:00 EST 2016
Cardiac telocytes and fibroblasts in primary culture: different morphologies and immunophenotypes.
PloS one
Bei Y,Zhou Q,Fu S,Lv D,Chen P,Chen Y,Wang F,Xiao J
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Nov 11 00:00:00 EST 2015
Galectin-3 deficiency exacerbates hyperglycemia and the endothelial response to diabetes.
Cardiovascular diabetology
Darrow AL,Shohet RV
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Sat Jun 06 00:00:00 EDT 2015
Endothelial Gata5 transcription factor regulates blood pressure.
Nature communications
Messaoudi S,He Y,Gutsol A,Wight A,Hébert RL,Vilmundarson RO,Makrigiannis AP,Chalmers J,Hamet P,Tremblay J,McPherson R,Stewart AFR,Touyz RM,Nemer M
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Nov 30 00:00:00 EST 2015
Endothelial Gata5 transcription factor regulates blood pressure.
Nature communications
Messaoudi S,He Y,Gutsol A,Wight A,Hébert RL,Vilmundarson RO,Makrigiannis AP,Chalmers J,Hamet P,Tremblay J,McPherson R,Stewart AFR,Touyz RM,Nemer M
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Nov 30 00:00:00 EST 2015
Reprogramming human endothelial cells to haematopoietic cells requires vascular induction.
Nature
Sandler VM,Lis R,Liu Y,Kedem A,James D,Elemento O,Butler JM,Scandura JM,Rafii S
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Jul 17 00:00:00 EDT 2014
Spatially restricted Hedgehog signalling regulates HGF-induced branching of the adult prostate.
Nature cell biology
Lim A,Shin K,Zhao C,Kawano S,Beachy PA
11-0451 was used in Flow cytometry/Cell sorting to study how spatially restricting Hedgehog signalling can regulate HGF-induced branching of the adult prostate.
Mon Dec 01 00:00:00 EST 2014
Endothelial C-type natriuretic peptide maintains vascular homeostasis.
The Journal of clinical investigation
Moyes AJ,Khambata RS,Villar I,Bubb KJ,Baliga RS,Lumsden NG,Xiao F,Gane PJ,Rebstock AS,Worthington RJ,Simone MI,Mota F,Rivilla F,Vallejo S,Peiró C,Sánchez Ferrer CF,Djordjevic S,Caulfield MJ,MacAllister RJ,Selwood DL,Ahluwalia A,Hobbs AJ
11-0451 was used in Flow cytometry/Cell sorting to evaluate mice with endothelial-specific deletion of C-type natriuretic peptide (CNP), showing that it is essential for multiple aspects of vascular regulation.
Mon Sep 01 00:00:00 EDT 2014
18-HEPE, an n-3 fatty acid metabolite released by macrophages, prevents pressure overload-induced maladaptive cardiac remodeling.
The Journal of experimental medicine
Endo J,Sano M,Isobe Y,Fukuda K,Kang JX,Arai H,Arita M
11-0451 was used in Flow cytometry/Cell sorting to study the ability of an eicosapentaenoic acid metabolite to inhibit macrophage-mediated proinflammatory activation of cardiac fibroblasts.
Mon Jul 28 00:00:00 EDT 2014
The roles of blood-derived macrophages and resident microglia in the neuroinflammatory response to implanted intracortical microelectrodes.
Biomaterials
Ravikumar M,Sunil S,Black J,Barkauskas DS,Haung AY,Miller RH,Selkirk SM,Capadona JR
11-0451 was used in Flow cytometry/Cell sorting to characterise the role of infiltrating blood-derived cells in mediating neurodegeneration for the purpose of improving implanted microelectrode performance.
Mon Sep 01 00:00:00 EDT 2014
Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells.
Journal of biomedical science
Cheng CC,Lee YH,Lin SP,Huangfu WC,Liu IH
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Mar 13 00:00:00 EDT 2014
Astrocytic transforming growth factor-beta signaling reduces subacute neuroinflammation after stroke in mice.
Glia
Cekanaviciute E,Fathali N,Doyle KP,Williams AM,Han J,Buckwalter MS
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Aug 01 00:00:00 EDT 2014
Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.
Stem cells (Dayton, Ohio)
Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu May 01 00:00:00 EDT 2014
Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.
Stem cells (Dayton, Ohio)
Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu May 01 00:00:00 EDT 2014
Human CD4+ HLA-G+ regulatory T cells are potent suppressors of graft-versus-host disease in vivo.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Pankratz S,Bittner S,Herrmann AM,Schuhmann MK,Ruck T,Meuth SG,Wiendl H
11-0451 was used in Flow cytometry/Cell sorting to compare properties and molecular characteristics of human CD4(+) Treg cells using in vitro and in vivo studies.
Fri Aug 01 00:00:00 EDT 2014
Bone marrow mesenchymal stem cells provide an antibiotic-protective niche for persistent viable Mycobacterium tuberculosis that survive antibiotic treatment.
The American journal of pathology
Beamer G,Major S,Das B,Campos-Neto A
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Dec 01 00:00:00 EST 2014
Prolactin-induced prostate tumorigenesis links sustained Stat5 signaling with the amplification of basal/stem cells and emergence of putative luminal progenitors.
The American journal of pathology
Sackmann-Sala L,Chiche A,Mosquera-Garrote N,Boutillon F,Cordier C,Pourmir I,Pascual-Mathey L,Kessal K,Pigat N,Camparo P,Goffin V
11-0451 was used in Flow cytometry/Cell sorting to provide a deeper understanding of the initial stages of prostate tumorigenesis induced by prolactin.
Sat Nov 01 00:00:00 EDT 2014
CD36-mediated hematoma absorption following intracerebral hemorrhage: negative regulation by TLR4 signaling.
Journal of immunology (Baltimore, Md. : 1950)
Fang H,Chen J,Lin S,Wang P,Wang Y,Xiong X,Yang Q
11-0451 was used in Flow cytometry/Cell sorting to study the function and potential mechanism of CD36 in hematoma absorption using in vitro and in vivo intracerebral hemorrhage models.
Sun Jun 15 00:00:00 EDT 2014
Priming of microglia in a DNA-repair deficient model of accelerated aging.
Neurobiology of aging
Raj DD,Jaarsma D,Holtman IR,Olah M,Ferreira FM,Schaafsma W,Brouwer N,Meijer MM,de Waard MC,van der Pluijm I,Brandt R,Kreft KL,Laman JD,de Haan G,Biber KP,Hoeijmakers JH,Eggen BJ,Boddeke HW
11-0451 was used in Flow cytometry/Cell sorting to study relationship between age and enhanced sensitivity of microglia to inflammatory stimuli.
Mon Sep 01 00:00:00 EDT 2014
Identification of hematopoietic-specific regulatory elements from the CD45 gene and use for lentiviral tracking of transplanted cells.
Experimental hematology
Duong KL,Das S,Yu S,Barr JY,Jena S,Kim E,Zavazava N,Colgan JD,Xue HH,Levasseur DN
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Sep 01 00:00:00 EDT 2014
DNA methylation of E-cadherin is a priming mechanism for prostate development.
Developmental biology
Keil KP,Abler LL,Mehta V,Altmann HM,Laporta J,Plisch EH,Suresh M,Hernandez LL,Vezina CM
11-0451 was used in Flow cytometry/Cell sorting to investigate the parallels between the signalling during prostate cancer development and prostate organogenesis.
Sat Mar 15 00:00:00 EDT 2014
Adipocytes arise from multiple lineages that are heterogeneously and dynamically distributed.
Nature communications
Sanchez-Gurmaches J,Guertin DA
11-0451 was used in Flow cytometry/Cell sorting to establish a framework for adipose tissue development to explain body fat patterning variations in lipodystrophic or obese humans.
Thu Jun 19 00:00:00 EDT 2014
Chronic thoracic spinal cord injury impairs CD8+ T-cell function by up-regulating programmed cell death-1 expression.
Journal of neuroinflammation
Zha J,Smith A,Andreansky S,Bracchi-Ricard V,Bethea JR
11-0451 was used in Flow cytometry/Cell sorting to investigate CD8+ T-cell function by up-regulating programmed cell death-1 expression in chronic thoracic spinal cord injury.
Tue Apr 01 00:00:00 EDT 2014
A new animal model of spontaneous autoimmune peripheral polyneuropathy: implications for Guillain-Barré syndrome.
Acta neuropathologica communications
Yang M,Rainone A,Shi XQ,Fournier S,Zhang J
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Jan 08 00:00:00 EST 2014
Modified extracorporeal photopheresis with cells from a healthy donor for acute graft-versus-host disease in a mouse model.
PloS one
Budde H,Kolb S,Salinas Tejedor L,Wulf G,Reichardt HM,Riggert J,Legler TJ
11-0451 was used in Flow cytometry/Cell sorting to demonstrate that conventional human extracorporeal photopheresis setup is effective in the mouse model of severe acute graft-versus-host disease.
Thu Mar 17 00:00:00 EDT 2016
Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.
PloS one
Xiao GY,Liu IH,Cheng CC,Chang CC,Lee YH,Cheng WT,Wu SC
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu May 28 00:00:00 EDT 2015
Activation of NLRP3 inflammasome by crystalline structures via cell surface contact.
Scientific reports
Hari A,Zhang Y,Tu Z,Detampel P,Stenner M,Ganguly A,Shi Y
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Dec 02 00:00:00 EST 2014
Regulation of PKM2 and Nrf2-ARE pathway during benzoquinone induced oxidative stress in yolk sac hematopoietic stem cells.
PloS one
Zhu J,Bi Z,Yang T,Wang W,Li Z,Huang W,Wang L,Zhang S,Zhou Y,Fan N,Bai Y,Song W,Wang C,Wang H,Bi Y
11-0451 was used in Flow cytometry/Cell sorting to investigate regulation of PKM2 and Nrf2-ARE pathway during benzoquinone induced oxidative stress in yolk sac hematopoietic stem cells.
Tue Sep 15 00:00:00 EDT 2015
The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation.
The Journal of biological chemistry
Eitas TK,Chou WC,Wen H,Gris D,Robbins GR,Brickey J,Oyama Y,Ting JP
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Feb 14 00:00:00 EST 2014
LSD1 promotes oxidative metabolism of white adipose tissue.
Nature communications
Duteil D,Metzger E,Willmann D,Karagianni P,Friedrichs N,Greschik H,Günther T,Buettner R,Talianidis I,Metzger D,Schüle R
11-0451 was used in Flow cytometry/Cell sorting to investigate the role of LSD1 as a key regulator of oxidative metabolism of white adipose tissue.
Tue Jun 10 00:00:00 EDT 2014
p62 links β-adrenergic input to mitochondrial function and thermogenesis.
The Journal of clinical investigation
Müller TD,Lee SJ,Jastroch M,Kabra D,Stemmer K,Aichler M,Abplanalp B,Ananthakrishnan G,Bhardwaj N,Collins S,Divanovic S,Endele M,Finan B,Gao Y,Habegger KM,Hembree J,Heppner KM,Hofmann S,Holland J,Küchler D,Kutschke M,Krishna R,Lehti M,Oelkrug R,Ottaway N,Perez-Tilve D,Raver C,Walch AK,Schriever SC,Speakman J,Tseng YH,Diaz-Meco M,Pfluger PT,Moscat J,Tschöp MH
11-0451 was used in Flow cytometry/Cell sorting to elucidate the mechanisms underlying the role of the scaffold protein p62 in the control of metabolic homeostasis and obesity.
Tue Jan 01 00:00:00 EST 2013
VEGF-A regulated by progesterone governs uterine angiogenesis and vascular remodelling during pregnancy.
EMBO molecular medicine
Kim M,Park HJ,Seol JW,Jang JY,Cho YS,Kim KR,Choi Y,Lydon JP,Demayo FJ,Shibuya M,Ferrara N,Sung HK,Nagy A,Alitalo K,Koh GY
11-0451 was used in Flow cytometry/Cell sorting to investigate the role of two vascular growth factor receptors in the regulation of angiogenesis in rapidly growing and regressing uteri.
Sun Sep 01 00:00:00 EDT 2013
Parental dietary fat intake alters offspring microbiome and immunity.
Journal of immunology (Baltimore, Md. : 1950)
Myles IA,Fontecilla NM,Janelsins BM,Vithayathil PJ,Segre JA,Datta SK
11-0451 was used in Flow cytometry/Cell sorting to reveal that parental fat consumption can leave a "lard legacy", impacting offspring immunity and health.
Sun Sep 15 00:00:00 EDT 2013
Ganciclovir prophylaxis improves late murine cytomegalovirus-induced renal allograft damage.
Transplantation
Shimamura M,Seleme MC,Guo L,Saunders U,Schoeb TR,George JF,Britt WJ
11-0451 was used in Flow cytometry/Cell sorting to examine the lasting effect of Ganciclovir treatment on renal allografts after the discontinuation of prophylaxis.
Tue Jan 15 00:00:00 EST 2013
MiR-193b and miR-365-1 are not required for the development and function of brown fat in the mouse.
RNA biology
Feuermann Y,Kang K,Gavrilova O,Haetscher N,Jang SJ,Yoo KH,Jiang C,Gonzalez FJ,Robinson GW,Hennighausen L
11-0451 was used in Flow cytometry/Cell sorting to investigate the contributions of two microRNAs to the development of brown adipose tissue in vivo using mouse genetics.
Sun Dec 01 00:00:00 EST 2013
Protective role of small pigment epithelium-derived factor (PEDF) peptide in diabetic renal injury.
American journal of physiology. Renal physiology
Awad AS,Gao T,Gvritishvili A,You H,Liu Y,Cooper TK,Reeves WB,Tombran-Tink J
11-0451 was used in Flow cytometry/Cell sorting to demonstrate the therapeutic potential of the pigment epithelium-derived factor fragment, P78-PEDF, for diabetic nephropathy.
Sun Sep 15 00:00:00 EDT 2013
Alveolar epithelial dynamics in postpneumonectomy lung growth.
Anatomical record (Hoboken, N.J. : 2007)
Chamoto K,Gibney BC,Ackermann M,Lee GS,Konerding MA,Tsuda A,Mentzer SJ
11-0451 was used in Flow cytometry/Cell sorting to investigate the relationship between epithelial and endothelial cells within the alveolus in post-pneumonectomy lung growth.
Fri Mar 01 00:00:00 EST 2013
Migration of CD11b+ accessory cells during murine lung regeneration.
Stem cell research
Chamoto K,Gibney BC,Lee GS,Ackermann M,Konerding MA,Tsuda A,Mentzer SJ
11-0451 was used in Flow cytometry/Cell sorting to characterise the factors contributing to neoalveolarization within 21 days of pneumonectomy.
Wed May 01 00:00:00 EDT 2013
Canonical Wnt signaling promotes early hematopoietic progenitor formation and erythroid specification during embryonic stem cell differentiation.
PloS one
Tarafdar A,Dobbin E,Corrigan P,Freeburn R,Wheadon H
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunofluorescence
Tue Jul 29 00:00:00 EDT 2014
Collagen VI regulates satellite cell self-renewal and muscle regeneration.
Nature communications
Urciuolo A,Quarta M,Morbidoni V,Gattazzo F,Molon S,Grumati P,Montemurro F,Tedesco FS,Blaauw B,Cossu G,Vozzi G,Rando TA,Bonaldo P
Mon Dec 30 00:00:00 EST 2013
Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets.
PloS one
El-Zaatari M,Kao JY,Tessier A,Bai L,Hayes MM,Fontaine C,Eaton KA,Merchant JL
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Sep 10 00:00:00 EDT 2013
Tumorigenic cells are common in mouse MPNSTs but their frequency depends upon tumor genotype and assay conditions.
Cancer cell
Buchstaller J,McKeever PE,Morrison SJ
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Feb 14 00:00:00 EST 2012
Autophagy links inflammasomes to atherosclerotic progression.
Cell metabolism
Razani B,Feng C,Coleman T,Emanuel R,Wen H,Hwang S,Ting JP,Virgin HW,Kastan MB,Semenkovich CF
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunofluorescence
Wed Apr 04 00:00:00 EDT 2012
Xenografted islet cell clusters from INSLEA29Y transgenic pigs rescue diabetes and prevent immune rejection in humanized mice.
Diabetes
Klymiuk N,van Buerck L,Bähr A,Offers M,Kessler B,Wuensch A,Kurome M,Thormann M,Lochner K,Nagashima H,Herbach N,Wanke R,Seissler J,Wolf E
11-0451 was used in Flow cytometry/Cell sorting to provide a report on transgenic pigs with β-cell-specific expression of LEA29Y and their application as donors in a xenotransplantation model.
Fri Jun 01 00:00:00 EDT 2012
Identification of a microglia phenotype supportive of remyelination.
Glia
Olah M,Amor S,Brouwer N,Vinet J,Eggen B,Biber K,Boddeke HW
Wed Feb 01 00:00:00 EST 2012
PPARγ/RXRα-induced and CD36-mediated microglial amyloid-β phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Yamanaka M,Ishikawa T,Griep A,Axt D,Kummer MP,Heneka MT
11-0451 was used in Flow cytometry/Cell sorting to demonstrate the potential benefit of microglial clearance for the prevention of Alzheimer's disease.
Wed Nov 28 00:00:00 EST 2012
Etv2 is expressed in the yolk sac hematopoietic and endothelial progenitors and regulates Lmo2 gene expression.
Stem cells (Dayton, Ohio)
Koyano-Nakagawa N,Kweon J,Iacovino M,Shi X,Rasmussen TL,Borges L,Zirbes KM,Li T,Perlingeiro RC,Kyba M,Garry DJ
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Wed Aug 01 00:00:00 EDT 2012
Transgenic expression of interferon-γ in mouse stomach leads to inflammation, metaplasia, and dysplasia.
The American journal of pathology
Syu LJ,El-Zaatari M,Eaton KA,Liu Z,Tetarbe M,Keeley TM,Pero J,Ferris J,Wilbert D,Kaatz A,Zheng X,Qiao X,Grachtchouk M,Gumucio DL,Merchant JL,Samuelson LC,Dlugosz AA
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Sat Dec 01 00:00:00 EST 2012
A model of GAG/MIP-2/CXCR2 interfaces and its functional effects.
Biochemistry
Rajasekaran D,Keeler C,Syed MA,Jones MC,Harrison JK,Wu D,Bhandari V,Hodsdon ME,Lolis EJ
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Jul 17 00:00:00 EDT 2012
Delta-like ligand (DLL)1 expression in early mouse decidua and its localization to uterine natural killer cells.
PloS one
Degaki KY,Chen Z,Yamada AT,Croy BA
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunofluorescence
Tue Jun 25 00:00:00 EDT 2013
Cell type-associated differences in migration, survival, and immunogenicity following grafting in CNS tissue.
Cell transplantation
Praet J,Reekmans K,Lin D,De Vocht N,Bergwerf I,Tambuyzer B,Daans J,Hens N,Goossens H,Pauwels P,Berneman Z,Van der Linden A,Ponsaerts P
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Dec 06 00:00:00 EST 2013
Deleterious effect of the IL-23/IL-17A axis and γδT cells on left ventricular remodeling after myocardial infarction.
Journal of the American Heart Association
Yan X,Shichita T,Katsumata Y,Matsuhashi T,Ito H,Ito K,Anzai A,Endo J,Tamura Y,Kimura K,Fujita J,Shinmura K,Shen W,Yoshimura A,Fukuda K,Sano M
11-0451 was used in Flow cytometry/Cell sorting to explore potential immune pathways involved in left ventricular remodelling as possible preventative therapeutic options.
Mon Oct 01 00:00:00 EDT 2012
Interferon-γ production by neutrophils during bacterial pneumonia in mice.
American journal of respiratory and critical care medicine
Yamada M,Gomez JC,Chugh PE,Lowell CA,Dinauer MC,Dittmer DP,Doerschuk CM
11-0451 was used in Flow cytometry/Cell sorting to reveal that neutrophils produce IFN-γ early in the inflammatory response during pneumonia induced by some bacteria, but not others.
Sun May 15 00:00:00 EDT 2011
Chronic sphingosine 1-phosphate 1 receptor activation attenuates early-stage diabetic nephropathy independent of lymphocytes.
Kidney international
Awad AS,Rouse MD,Khutsishvili K,Huang L,Bolton WK,Lynch KR,Okusa MD
11-0451 was used in Flow cytometry/Cell sorting to test whether the activation of S1P1 receptors (S1P1Rs) ameliorates renal injury in early-stage diabetic nephropathy (DN) in rats.
Sun May 01 00:00:00 EDT 2011
Arginase-2 mediates diabetic renal injury.
Diabetes
Morris SM,Gao T,Cooper TK,Kepka-Lenhart D,Awad AS
11-0451 was used in Flow cytometry/Cell sorting to determine whether renal arginase activity or expression is increased in diabetes and whether arginase plays a role in development of diabetic nephropathy (DN), showing that arginase-2 mediates diabetic renal injury.
Tue Nov 01 00:00:00 EDT 2011
ER71 directs mesodermal fate decisions during embryogenesis.
Development (Cambridge, England)
Rasmussen TL,Kweon J,Diekmann MA,Belema-Bedada F,Song Q,Bowlin K,Shi X,Ferdous A,Li T,Kyba M,Metzger JM,Koyano-Nakagawa N,Garry DJ
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2011
The anti-tumor effect of resveratrol alone or in combination with immunotherapy in a neuroblastoma model.
Cancer immunology, immunotherapy : CII
Soto BL,Hank JA,Van De Voort TJ,Subramanian L,Polans AS,Rakhmilevich AL,Yang RK,Seo S,Kim K,Reisfeld RA,Gillies SD,Sondel PM
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunohistochemistry
Sun May 01 00:00:00 EDT 2011
Effect of topical azithromycin on corneal innate immune responses.
Investigative ophthalmology & visual science
Sadrai Z,Hajrasouliha AR,Chauhan S,Saban DR,Dastjerdi MH,Dana R
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Tue Apr 19 00:00:00 EDT 2011
Monocyte/macrophage chemokine receptor CCR2 mediates diabetic renal injury.
American journal of physiology. Renal physiology
Awad AS,Kinsey GR,Khutsishvili K,Gao T,Bolton WK,Okusa MD
11-0451 was used in Flow cytometry/Cell sorting to study the mediation of diabetic renal injury by monocyte/macrophage chemokine receptor CCR2.
Thu Dec 01 00:00:00 EST 2011
Myeloid cells migrate in response to IL-24.
Cytokine
Buzas K,Oppenheim JJ,Zack Howard OM
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2011
Clinical potential of intravenous neural stem cell delivery for treatment of neuroinflammatory disease in mice?
Cell transplantation
Reekmans KP,Praet J,De Vocht N,Tambuyzer BR,Bergwerf I,Daans J,Baekelandt V,Vanhoutte G,Goossens H,Jorens PG,Ysebaert DK,Chatterjee S,Pauwels P,Van Marck E,Berneman ZN,Van der Linden A,Ponsaerts P
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Fri Dec 09 00:00:00 EST 2011
Angiogenesis gene expression in murine endothelial cells during post-pneumonectomy lung growth.
Respiratory research
Lin M,Chamoto K,Gibney BC,Lee GS,Collings-Simpson D,Houdek J,Konerding MA,Tsuda A,Mentzer SJ
11-0451 was used in Flow cytometry/Cell sorting to investigate the genes involved in an experimental model of alveolar capillary angiogenesis, identifying 22 genes expressed in CD31+ cells with a significantly increased transcription.
Wed Jul 27 00:00:00 EDT 2011
Isolation, cultivation and characterization of adult murine prostate stem cells.
Nature protocols
Lukacs RU,Goldstein AS,Lawson DA,Cheng D,Witte ON
11-0451 was used in Flow cytometry/Cell sorting to develop a protocol to isolate, cultivate and characterise adult murine prostate stem cells, allowing further studies in organ replenishment and their role in cancer initiation.
Thu Apr 01 00:00:00 EDT 2010
Activation of sphingosine-1-phosphate 1 receptor in the proximal tubule protects against ischemia-reperfusion injury.
Journal of the American Society of Nephrology : JASN
Bajwa A,Jo SK,Ye H,Huang L,Dondeti KR,Rosin DL,Haase VH,Macdonald TL,Lynch KR,Okusa MD
11-0451 was used in Flow cytometry/Cell sorting to investigate the effects of sphingosine-1-phosphate receptor agonists on acute kidney injury.
Tue Jun 01 00:00:00 EDT 2010
FLT-3 expression and function on microglia in multiple sclerosis.
Experimental and molecular pathology
DeBoy CA,Rus H,Tegla C,Cudrici C,Jones MV,Pardo CA,Small D,Whartenby KA,Calabresi PA
11-0451 was used in Flow cytometry/Cell sorting to study the expression and function of FLT-3 in microglia in multiple sclerosis, suggesting that FLT-3 could be a therapeutic target to mitigate CNS inflammation.
Fri Oct 01 00:00:00 EDT 2010
Influence of 5 major Salmonella pathogenicity islands on NK cell depletion in mice infected with Salmonella enterica serovar Enteritidis.
BMC microbiology
Karasova D,Sebkova A,Havlickova H,Sisak F,Volf J,Faldyna M,Ondrackova P,Kummer V,Rychlik I
11-0451 was used in Flow cytometry/Cell sorting to investigate the colonisation and early immune response of Balb/C mice to infection with Salmonella Enteritidis and isogenic pathogenicity island free mutants.
Fri Mar 12 00:00:00 EST 2010
Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development.
Hepatology (Baltimore, Md.)
Asahina K,Tsai SY,Li P,Ishii M,Maxson RE,Sucov HM,Tsukamoto H
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunofluorescence
Sun Mar 01 00:00:00 EST 2009
Involvement of IQGAP3, a regulator of Ras/ERK-related cascade, in hepatocyte proliferation in mouse liver regeneration and development.
Journal of cellular physiology
Kunimoto K,Nojima H,Yamazaki Y,Yoshikawa T,Okanoue T,Tsukita S
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Immunofluorescence
Tue Sep 01 00:00:00 EDT 2009
Dynamic imaging of T cell-parasite interactions in the brains of mice chronically infected with Toxoplasma gondii.
Journal of immunology (Baltimore, Md. : 1950)
Schaeffer M,Han SJ,Chtanova T,van Dooren GG,Herzmark P,Chen Y,Roysam B,Striepen B,Robey EA
11-0451 was used in Flow cytometry/Cell sorting to directly observe the dynamics of T cell-parasite interactions within living tissue and further understand immune responses to persistent pathogens in the brain.
Fri May 15 00:00:00 EDT 2009
Early chimerism threshold predicts sustained engraftment and NK-cell tolerance in prenatal allogeneic chimeras.
Blood
Durkin ET,Jones KA,Rajesh D,Shaaban AF
11-0451 was used in Flow cytometry/Cell sorting to study the effect chimerism level on engraftment and host natural killer (NK)-cell education in a murine model of in utero hematopoietic cell transplantation (IUHCT), showing that early chimerism threshold predicts sustained engraftment and NK-cell tolerance in prenatal allogeneic chimeras.
Mon Dec 15 00:00:00 EST 2008
Mechanism of T cell tolerance induction by murine hepatic Kupffer cells.
Hepatology (Baltimore, Md.)
You Q,Cheng L,Kedl RM,Ju C
11-0451 was used in Flow cytometry/Cell sorting to examine the ability of Kupffer cells to present antigens and to suppress T cell activation by splenic dendritic cells.
Mon Sep 01 00:00:00 EDT 2008
Wnt1 expression induces short-range and long-range cell recruitments that modify mammary tumor development and are not induced by a cell-autonomous beta-catenin effector.
Cancer research
Kim YC,Clark RJ,Ranheim EA,Alexander CM
11-0451 was used in Flow cytometry/Cell sorting to show that bone marrow-derived cells are recruited to the stroma of Wnt1-induced tumors, where they differentiate into multiple cell types.
Mon Dec 15 00:00:00 EST 2008
Region-specific expression of immunoregulatory proteins on microglia in the healthy CNS.
Glia
de Haas AH,Boddeke HW,Biber K
11-0451 was used in Flow cytometry/Cell sorting to evaluate the existence of distinct microglia phenotypes in various regions of the healthy, adult mouse central nervous system.
Sun Jun 01 00:00:00 EDT 2008
Loss of extracellular superoxide dismutase leads to acute lung damage in the presence of ambient air: a potential mechanism underlying adult respiratory distress syndrome.
The American journal of pathology
Gongora MC,Lob HE,Landmesser U,Guzik TJ,Martin WD,Ozumi K,Wall SM,Wilson DS,Murthy N,Gravanis M,Fukai T,Harrison DG
11-0451 was used in Flow cytometry/Cell sorting to study the role of acute SOD3 reduction in lung injury.
Wed Oct 01 00:00:00 EDT 2008
G-CSF induction early in uropathogenic Escherichia coli infection of the urinary tract modulates host immunity.
Cellular microbiology
Ingersoll MA,Kline KA,Nielsen HV,Hultgren SJ
11-0451 was used in Immunohistochemistry on frozen tissues to investigate the mechanism of recruitment of neutrophils to the bladder during urinary tract infection, showing that G-CSF induction early in infection modulates host immunity.
Mon Dec 01 00:00:00 EST 2008
Deletion of both ICAM-1 and C3 enhances severity of experimental autoimmune encephalomyelitis compared to C3-deficient mice.
Neuroscience letters
Smith SS,Ludwig M,Wohler JE,Bullard DC,Szalai AJ,Barnum SR
11-0451 was used in Flow cytometry/Cell sorting to examine experimental autoimmune encephalitis in ICAM-1 x C3 double knockout mice.
Fri Sep 12 00:00:00 EDT 2008
Differentiation of mouse embryonic stem cells into blood.
Current protocols in stem cell biology
Ma YD,Lugus JJ,Park C,Choi K
11-0451 was used in Flow cytometry/Cell sorting to develop protocols for the maintenance and differentiation of mouse embryonic stem cells into hematopoietic progenitors.
Tue Jul 01 00:00:00 EDT 2008
Optimized isolation enables ex vivo analysis of microglia from various central nervous system regions.
Glia
de Haas AH,Boddeke HW,Brouwer N,Biber K
Published figure using CD45 monoclonal antibody (Product # 11-0451-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2007
Disruption of the beta2-integrin CD11d (alphaDbeta2) gene fails to protect against experimental autoimmune encephalomyelitis.
Journal of neuroimmunology
Adams JE,Webb MS,Hu X,Staunton D,Barnum SR
11-0451 was used in Flow cytometry/Cell sorting to show that deletion of the β2-integrin CD11d has no effect on the development and progression of EAE.
Thu Mar 01 00:00:00 EST 2007
Lateral compartmentalization of T cell receptor versus CD45 by galectin-N-glycan binding and microfilaments coordinate basal and activation signaling.
The Journal of biological chemistry
Chen IJ,Chen HL,Demetriou M
11-0451 was used in Flow cytometry/Cell sorting to investigate the role of the galectin lattice and actin cytoskeleton in controlling microdomain structure and coordinating signal transduction across the plasma membrane.
Fri Nov 30 00:00:00 EST 2007
