Product References
A platinum@polymer-catechol nanobraker enables radio-immunotherapy for crippling melanoma tumorigenesis, angiogenesis, and radioresistance.
Bioactive materials
Li W,Yan J,Tian H,Li B,Wang G,Sang W,Zhang Z,Zhang X,Dai Y
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2023
Microbiota-assisted iron uptake promotes immune tolerance in the intestine.
Nature communications
Zhu L,Li G,Liang Z,Qi T,Deng K,Yu J,Peng Y,Zheng J,Song Y,Chang X
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Mon May 15 00:00:00 EDT 2023
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression.
Nature communications
Qi M,Xia Y,Wu Y,Zhang Z,Wang X,Lu L,Dai C,Song Y,Xu K,Ji W,Zhan L
45-0621-82 was used in Flow Cytometry to demonstrate that Lin28B promotes lung metastasis of breast cancer by building an immune-suppressive pre-metastatic niche.
Wed Feb 16 00:00:00 EST 2022
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression.
Nature communications
Qi M,Xia Y,Wu Y,Zhang Z,Wang X,Lu L,Dai C,Song Y,Xu K,Ji W,Zhan L
45-0621-82 was used in Flow Cytometry to demonstrate that Lin28B promotes lung metastasis of breast cancer by building an immune-suppressive pre-metastatic niche.
Wed Feb 16 00:00:00 EST 2022
Amphiphile-CpG vaccination induces potent lymph node activation and COVID-19 immunity in mice and non-human primates.
NPJ vaccines
Seenappa LM,Jakubowski A,Steinbuck MP,Palmer E,Haqq CM,Carter C,Fontenot J,Villinger F,McNeil LK,DeMuth PC
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Fri Oct 28 00:00:00 EDT 2022
Low immunogenicity of malaria pre-erythrocytic stages can be overcome by vaccination.
EMBO molecular medicine
Müller K,Gibbins MP,Roberts M,Reyes-Sandoval A,Hill AVS,Draper SJ,Matuschewski K,Silvie O,Hafalla JCR
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Fri Apr 09 00:00:00 EDT 2021
Sirt6 Regulates the Development of Medullary Thymic Epithelial Cells and Contributes to the Establishment of Central Immune Tolerance.
Frontiers in cell and developmental biology
Zhang Q,Liang Z,Zhang J,Lei T,Dong X,Su H,Chen Y,Zhang Z,Tan L,Zhao Y
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Wed Apr 21 00:00:00 EDT 2021
Trichinella spiralis Paramyosin Induces Colonic Regulatory T Cells to Mitigate Inflammatory Bowel Disease.
Frontiers in cell and developmental biology
Hao C,Wang W,Zhan B,Wang Z,Huang J,Sun X,Zhu X
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Tue Aug 03 00:00:00 EDT 2021
CD8+ T cells in the central nervous system of mice with herpes simplex infection are highly activated and express high levels of CCR5 and CXCR3.
Journal of neurovirology
Lind L,Svensson A,Thörn K,Krzyzowska M,Eriksson K
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
cDC1 Dependent Accumulation of Memory T Cells Is Required for Chronic Autoimmune Inflammation in Murine Testis.
Frontiers in immunology
Jing Y,Cao M,Zhang B,Long X,Wang X
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Fri Sep 24 00:00:00 EDT 2021
Evaluation of DNA-Launched Virus-Like Particle Vaccines in an Immune Competent Mouse Model of Chikungunya Virus Infection.
Vaccines
Rayner JO,Kim JH,Roberts RW,Wood RR,Fouty B,Solodushko V
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Fri Apr 02 00:00:00 EDT 2021
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory.
Cell reports
Cannons JL,Villarino AV,Kapnick SM,Preite S,Shih HY,Gomez-Rodriguez J,Kaul Z,Shibata H,Reilley JM,Huang B,Handon R,McBain IT,Gossa S,Wu T,Su HC,McGavern DB,O'Shea JJ,McGuire PJ,Uzel G,Schwartzberg PL
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Synchronous effects of targeted mitochondrial complex I inhibitors on tumor and immune cells abrogate melanoma progression.
iScience
AbuEid M,McAllister DM,McOlash L,Harwig MC,Cheng G,Drouillard D,Boyle KA,Hardy M,Zielonka J,Johnson BD,Hill RB,Kalyanaraman B,Dwinell MB
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Fri Jun 25 00:00:00 EDT 2021
Theranostic near-infrared-IIb emitting nanoprobes for promoting immunogenic radiotherapy and abscopal effects against cancer metastasis.
Nature communications
Li H,Wang M,Huang B,Zhu SW,Zhou JJ,Chen DR,Cui R,Zhang M,Sun ZJ
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Thu Dec 09 00:00:00 EST 2021
Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma.
Cell reports
Budhu S,Giese R,Gupta A,Fitzgerald K,Zappasodi R,Schad S,Hirschhorn D,Campesato LF,De Henau O,Gigoux M,Liu C,Mazo G,Deng L,Barker CA,Wolchok JD,Merghoub T
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Type 1 Cytotoxic T Cells Increase in Placenta after Intrauterine Inflammation.
Frontiers in immunology
Liu J,Liu Y,Panda S,Liu A,Lei J,Burd I
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Fri Dec 17 00:00:00 EST 2021
Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials.
EBioMedicine
Okada R,Furusawa A,Vermeer DW,Inagaki F,Wakiyama H,Kato T,Nagaya T,Choyke PL,Spanos WC,Allen CT,Kobayashi H
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Inhibition of TLR4 signaling protects mice from sensory and motor dysfunction in an animal model of autoimmune peripheral neuropathy.
Journal of neuroinflammation
Oladiran O,Shi XQ,Yang M,Fournier S,Zhang J
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Mon Mar 22 00:00:00 EDT 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis.
Nature communications
Wang G,Xie L,Li B,Sang W,Yan J,Li J,Tian H,Li W,Zhang Z,Tian Y,Dai Y
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Thu Sep 30 00:00:00 EDT 2021
Graded RhoA GTPase Expression in Treg Cells Distinguishes Tumor Immunity From Autoimmunity.
Frontiers in immunology
Kalim KW,Yang JQ,Modur V,Nguyen P,Li Y,Zheng Y,Guo F
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Tue Jan 11 00:00:00 EST 2022
Rate of Freeze Impacts the Survival and Immune Responses Post Cryoablation of Melanoma.
Frontiers in immunology
Yakkala C,Dagher J,Sempoux C,Chiang CL,Denys A,Kandalaft LE,Koppolu B,Duran R
45-0621-82 was used in Flow Cytometry to study fast freeze and slow freeze rates for their locoregional effectiveness and their ability to elicit immune responses in a B16F10 mouse model of melanoma.
Mon Dec 13 00:00:00 EST 2021
Intratumoral immunotherapy using platelet-cloaked nanoparticles enhances antitumor immunity in solid tumors.
Nature communications
Bahmani B,Gong H,Luk BT,Haushalter KJ,DeTeresa E,Previti M,Zhou J,Gao W,Bui JD,Zhang L,Fang RH,Zhang J
45-0621-82 was used in Immunohistochemistry to highlight the promise of locally delivering immunostimulatory payloads using biomimetic nanocarriers, which possess advantages such as enhanced biocompatibility and natural targeting affinities.
Wed Mar 31 00:00:00 EDT 2021
Analysis of T cells in mouse lymphoid tissue and blood with flow cytometry.
STAR protocols
Skordos I,Demeyer A,Beyaert R
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Fri Mar 19 00:00:00 EDT 2021
Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes.
Nature immunology
Abdelsamed HA,Zebley CC,Nguyen H,Rutishauser RL,Fan Y,Ghoneim HE,Crawford JC,Alfei F,Alli S,Ribeiro SP,Castellaw AH,McGargill MA,Jin H,Boi SK,Speake C,Serti E,Turka LA,Busch ME,Stone M,Deeks SG,Sekaly RP,Zehn D,James EA,Nepom GT,Youngblood B
45-0621 was used in Flow cytometry/Cell sorting to investigate the long-lived nature of these cells, we established a DNA methylation-based T cell 'multipotency index' and found that beta cell-specific CD8+ T cells retained a stem-like epigenetic multipotency score.
Fri May 01 00:00:00 EDT 2020
B Cell Diversification Is Uncoupled from SAP-Mediated Selection Forces in Chronic Germinal Centers within Peyer's Patches.
Cell reports
Biram A,Winter E,Denton AE,Zaretsky I,Dassa B,Bemark M,Linterman MA,Yaari G,Shulman Z
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Tue Feb 11 00:00:00 EST 2020
Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis.
Nature communications
Sidwell T,Liao Y,Garnham AL,Vasanthakumar A,Gloury R,Blume J,Teh PP,Chisanga D,Thelemann C,de Labastida Rivera F,Engwerda CR,Corcoran L,Kometani K,Kurosaki T,Smyth GK,Shi W,Kallies A
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Tue Jan 14 00:00:00 EST 2020
Localized cocktail chemoimmunotherapy after in situ gelation to trigger robust systemic antitumor immune responses.
Science advances
Chao Y,Liang C,Tao H,Du Y,Wu D,Dong Z,Jin Q,Chen G,Xu J,Xiao Z,Chen Q,Wang C,Chen J,Liu Z
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2020
ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.
Nature communications
Cao Y,Trillo-Tinoco J,Sierra RA,Anadon C,Dai W,Mohamed E,Cen L,Costich TL,Magliocco A,Marchion D,Klar R,Michel S,Jaschinski F,Reich RR,Mehrotra S,Cubillos-Ruiz JR,Munn DH,Conejo-Garcia JR,Rodriguez PC
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Wed Mar 20 00:00:00 EDT 2019
Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer.
Cell reports
Choi H,Deng J,Li S,Silk T,Dong L,Brea EJ,Houghton S,Redmond D,Zhong H,Boiarsky J,Akbay EA,Smith PD,Merghoub T,Wong KK,Wolchok JD
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Tue Apr 16 00:00:00 EDT 2019
Activated Peyer's patch B cells sample antigen directly from M cells in the subepithelial dome.
Nature communications
Komban RJ,Strömberg A,Biram A,Cervin J,Lebrero-Fernández C,Mabbott N,Yrlid U,Shulman Z,Bemark M,Lycke N
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Mon Jun 03 00:00:00 EDT 2019
Local immunomodulation Fas ligand-engineered biomaterials achieves allogeneic islet graft acceptance.
Nature materials
Headen DM,Woodward KB,Coronel MM,Shrestha P,Weaver JD,Zhao H,Tan M,Hunckler MD,Bowen WS,Johnson CT,Shea L,Yolcu ES,García AJ,Shirwan H
45-0621 was used in Flow cytometry/Cell sorting to study the effects of localised immunomodulation using microgels presenting an apoptotic form of the Fas ligand with streptavidin in diabetic mice.
Wed Aug 01 00:00:00 EDT 2018
MTOR signaling is essential for the development of thymic epithelial cells and the induction of central immune tolerance.
Autophagy
Liang Z,Zhang L,Su H,Luan R,Na N,Sun L,Zhao Y,Zhang X,Zhang Q,Li J,Zhang L,Zhao Y
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Fri Mar 22 00:00:00 EDT 2019
Varying Immunizations With Plasmodium Radiation-Attenuated Sporozoites Alter Tissue-Specific CD8+ T Cell Dynamics.
Frontiers in immunology
Frank R,Gabel M,Heiss K,Mueller AK,Graw F
Tue Jul 30 00:00:00 EDT 2019
C5aR1 regulates T follicular helper differentiation and chronic graft-versus-host disease bronchiolitis obliterans.
JCI insight
Verghese DA,Chun N,Paz K,Fribourg M,Woodruff TM,Flynn R,Hu Y,Xiong H,Zhang W,Yi Z,Du J,Blazar BR,Heeger PS
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Thu Dec 20 00:00:00 EST 2018
Helminth-induced IL-4 expands bystander memory CD8+ T cells for early control of viral infection.
Nature communications
Rolot M,Dougall AM,Chetty A,Javaux J,Chen T,Xiao X,Machiels B,Selkirk ME,Maizels RM,Hokke C,Denis O,Brombacher F,Vanderplasschen A,Gillet L,Horsnell WGC,Dewals BG
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Tue Oct 30 00:00:00 EDT 2018
Limited Foxp3+ Regulatory T Cells Response During Acute Trypanosoma cruzi Infection Is Required to Allow the Emergence of Robust Parasite-Specific CD8+ T Cell Immunity.
Frontiers in immunology
Araujo Furlan CL,Tosello Boari J,Rodriguez C,Canale FP,Fiocca Vernengo F,Boccardo S,Beccaria CG,Adoue V,Joffre O,Gruppi A,Montes CL,Acosta Rodriguez EV
45-0621 was used in Flow cytometry/Cell sorting to study the role of regulatory T cells during Trypanosoma cruzi infection.
Thu Sep 26 00:00:00 EDT 2019
Stability and function of regulatory T cells expressing the transcription factor T-bet.
Nature
Levine AG,Mendoza A,Hemmers S,Moltedo B,Niec RE,Schizas M,Hoyos BE,Putintseva EV,Chaudhry A,Dikiy S,Fujisawa S,Chudakov DM,Treuting PM,Rudensky AY
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Thu Jun 15 00:00:00 EDT 2017
Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment.
Cancer cell
Turaj AH,Hussain K,Cox KL,Rose-Zerilli MJJ,Testa J,Dahal LN,Chan HTC,James S,Field VL,Carter MJ,Kim HJ,West JJ,Thomas LJ,He LZ,Keler T,Johnson PWM,Al-Shamkhani A,Thirdborough SM,Beers SA,Cragg MS,Glennie MJ,Lim SH
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Mon Dec 11 00:00:00 EST 2017
Excessive expression of miR-27 impairs Treg-mediated immunological tolerance.
The Journal of clinical investigation
Cruz LO,Hashemifar SS,Wu CJ,Cho S,Nguyen DT,Lin LL,Khan AA,Lu LF
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.
The Journal of experimental medicine
Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Mon Jun 05 00:00:00 EDT 2017
Anti-CD137 Suppresses Tumor Growth by Blocking Reverse Signaling by CD137 Ligand.
Cancer research
Kang SW,Lee SC,Park SH,Kim J,Kim HH,Lee HW,Seo SK,Kwon BS,Cho HR,Kwon B
45-0621-82 was used in Flow Cytometry to report findings related to reverse signaling by CD137 ligand (CD137L) in antigen-presenting dendritic cells (DC) in tumors that address these paradoxical results.
Wed Nov 01 00:00:00 EDT 2017
Modulation of Endoplasmic Reticulum Stress Controls CD4+ T-cell Activation and Antitumor Function.
Cancer immunology research
Thaxton JE,Wallace C,Riesenberg B,Zhang Y,Paulos CM,Beeson CC,Liu B,Li Z
45-0621 was used in Flow cytometry/Cell sorting to investigate whether the endoplasmic reticulum stress response may be important for CD4+ T-cell activation and whether gp96 is integral to this process.
Tue Aug 01 00:00:00 EDT 2017
Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice.
Neurobiology of disease
MacPherson KP,Sompol P,Kannarkat GT,Chang J,Sniffen L,Wildner ME,Norris CM,Tansey MG
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
The Ox40/Ox40 Ligand Pathway Promotes Pathogenic Th Cell Responses, Plasmablast Accumulation, and Lupus Nephritis in NZB/W F1 Mice.
Journal of immunology (Baltimore, Md. : 1950)
Sitrin J,Suto E,Wuster A,Eastham-Anderson J,Kim JM,Austin CD,Lee WP,Behrens TW
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Tue Aug 15 00:00:00 EDT 2017
Chemokine Receptor-Dependent Control of Skin Tissue-Resident Memory T Cell Formation.
Journal of immunology (Baltimore, Md. : 1950)
Zaid A,Hor JL,Christo SN,Groom JR,Heath WR,Mackay LK,Mueller SN
45-0621 was used in Flow cytometry/Cell sorting to examine the signals required for the migration of tissue-resident memory T cells within the constrained epidermal environment.
Sun Oct 01 00:00:00 EDT 2017
Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages.
EBioMedicine
Li Y,Liu X,Duan W,Tian H,Zhu G,He H,Yao S,Yi S,Song W,Tang H
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.
Science translational medicine
Dendrou CA,Cortes A,Shipman L,Evans HG,Attfield KE,Jostins L,Barber T,Kaur G,Kuttikkatte SB,Leach OA,Desel C,Faergeman SL,Cheeseman J,Neville MJ,Sawcer S,Compston A,Johnson AR,Everett C,Bell JI,Karpe F,Ultsch M,Eigenbrot C,McVean G,Fugger L
45-0621 was used in Flow cytometry/Cell sorting to reveal a protective homozygous effect that defined a signalling optimum between autoimmunity and immunodeficiency and identified TYK2 as a potential drug target for autoimmune disorders.
Wed Nov 02 00:00:00 EDT 2016
Dendritic cell sphingosine-1-phosphate lyase regulates thymic egress.
The Journal of experimental medicine
Zamora-Pineda J,Kumar A,Suh JH,Zhang M,Saba JD
45-0621 was used in Flow cytometry/Cell sorting to investigate the role of dendritic cell sphingosine-1-phosphate lyase in thymic egress.
Mon Nov 14 00:00:00 EST 2016
Unexpected Role for Adaptive αβTh17 Cells in Acute Respiratory Distress Syndrome.
Journal of immunology (Baltimore, Md. : 1950)
Li JT,Melton AC,Su G,Hamm DE,LaFemina M,Howard J,Fang X,Bhat S,Huynh KM,O'Kane CM,Ingram RJ,Muir RR,McAuley DF,Matthay MA,Sheppard D
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
Targeted Mutation of Nuclear Bone Morphogenetic Protein 2 Impairs Secondary Immune Response in a Mouse Model.
BioMed research international
Olsen DS,Goar WA,Nichols BA,Bailey KT,Christensen SL,Merriam KR,Reynolds PR,Wilson E,Weber KS,Bridgewater LC
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Myelin-specific T helper 17 cells promote adult hippocampal neurogenesis through indirect mechanisms.
F1000Research
Niebling J,E Rünker A,Schallenberg S,Kretschmer K,Kempermann G
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Fri Mar 06 00:00:00 EST 2020
STAT4 is required for IL-23 responsiveness in Th17 memory cells and NKT cells.
JAK-STAT
Glosson-Byers NL,Sehra S,Kaplan MH
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2015
Sequential transcriptional changes dictate safe and effective antigen-specific immunotherapy.
Nature communications
Burton BR,Britton GJ,Fang H,Verhagen J,Smithers B,Sabatos-Peyton CA,Carney LJ,Gough J,Strobel S,Wraith DC
45-0621 was used in Flow cytometry/Cell sorting to study the markers significant for antigen-specific immunotherapy such as regulatory CD4(+) T-cell transcription factors.
Wed Sep 03 00:00:00 EDT 2014
A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models.
The Journal of clinical investigation
Dai X,James RG,Habib T,Singh S,Jackson S,Khim S,Moon RT,Liggitt D,Wolf-Yadlin A,Buckner JH,Rawlings DJ
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Wed May 01 00:00:00 EDT 2013
Cellular-FLIP, Raji isoform (c-FLIP R) modulates cell death induction upon T-cell activation and infection.
European journal of immunology
Telieps T,Ewald F,Gereke M,Annemann M,Rauter Y,Schuster M,Ueffing N,von Smolinski D,Gruber AD,Bruder D,Schmitz I
45-0621 was used in Flow cytometry/Cell sorting to study the induction of endogenous murine cellular-FLIPR in activated lymphocytes.
Sat Jun 01 00:00:00 EDT 2013
Surveillance on the status of immune cells after Echinnococcus granulosus protoscoleces infection in Balb/c mice.
PloS one
Pan W,Zhou HJ,Shen YJ,Wang Y,Xu YX,Hu Y,Jiang YY,Yuan ZY,Ugwu CE,Cao JP
45-0621 was used in Flow cytometry/Cell sorting to investigate the systemic immune status of innate and adaptive immunity at 30, 180, 360 days post-infection in mice infected with E. granulousus.
Tue Jan 07 00:00:00 EST 2014
Breakdown in repression of IFN-γ mRNA leads to accumulation of self-reactive effector CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Chang PP,Lee SK,Hu X,Davey G,Duan G,Cho JH,Karupiah G,Sprent J,Heath WR,Bertram EM,Vinuesa CG
45-0621 was used in Flow cytometry/Cell sorting to identify a novel mechanism that affects the distribution of self-reactive cytotoxic effector cells.
Sun Jul 15 00:00:00 EDT 2012
Requirement for diverse TCR specificities determines regulatory T cell activity in a mouse model of autoimmune arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Oh S,Aitken M,Simons DM,Basehoar A,Garcia V,Kropf E,Caton AJ
45-0621 was used in Flow cytometry/Cell sorting to investigate why CD4(+)CD25(+)Foxp3(+) Tregs allow organ-specific autoimmunity, showing that polyclonal Tregs suppressed Th17 cell formation and prevented arthritis development, but clonotypic Tregs did not, indicating that diverse TCR specificities are required.
Tue May 01 00:00:00 EDT 2012
Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment.
Cell communication and signaling : CCS
Wiechert L,Németh J,Pusterla T,Bauer C,De Ponti A,Manthey S,Marhenke S,Vogel A,Klingmüller U,Hess J,Angel P
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Sat Dec 15 00:00:00 EST 2012
Modeling Sjögren's syndrome with Id3 conditional knockout mice.
Immunology letters
Guo Z,Li H,Han M,Xu T,Wu X,Zhuang Y
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Wed Mar 30 00:00:00 EDT 2011
IL-7 promotes T cell viability, trafficking, and functionality and improves survival in sepsis.
Journal of immunology (Baltimore, Md. : 1950)
Unsinger J,McGlynn M,Kasten KR,Hoekzema AS,Watanabe E,Muenzer JT,McDonough JS,Tschoep J,Ferguson TA,McDunn JE,Morre M,Hildeman DA,Caldwell CC,Hotchkiss RS
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2010
Synergistic antitumor effects of regulatory T cell blockade combined with pemetrexed in murine malignant mesothelioma.
Journal of immunology (Baltimore, Md. : 1950)
Anraku M,Tagawa T,Wu L,Yun Z,Keshavjee S,Zhang L,Johnston MR,de Perrot M
45-0621 was used in Flow cytometry/Cell sorting to evaluate the potential of a combined Treg blockade-permetrexed anti-tumour treatment.
Thu Jul 15 00:00:00 EDT 2010
Modulation of naive CD4+ T-cell responses to an airway antigen during pulmonary mycobacterial infection.
Infection and immunity
Anis MM,Fulton SA,Reba SM,Harding CV,Boom WH
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 45-0621-82) in Flow Cytometry
Tue May 01 00:00:00 EDT 2007