Product References
Berberine plays a cardioprotective role by inhibiting macrophage Wnt5a/β-catenin pathway in the myocardium of mice after myocardial infarction.
Phytotherapy research : PTR
Tian CX,Li MY,Shuai XX,Jiang F,Dong YL,Gui Y,Zhang ZL,Qin RJ,Kang ZY,Lin L,Sarapultsev A,Wu B,Luo SS,Hu DS
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2023
Tumor-specific cholinergic CD4+ T lymphocytes guide immunosurveillance of hepatocellular carcinoma.
Nature cancer
Zheng C,Snow BE,Elia AJ,Nechanitzky R,Dominguez-Brauer C,Liu S,Tong Y,Cox MA,Focaccia E,Wakeham AC,Haight J,Tobin C,Hodgson K,Gill KT,Ma W,Berger T,Heikenwälder M,Saunders ME,Fortin J,Leung SY,Mak TW
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2023
PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation.
Nature communications
Linnerbauer M,Beyer T,Nirschl L,Farrenkopf D,Lößlein L,Vandrey O,Peter A,Tsaktanis T,Kebir H,Laplaud D,Oellinger R,Engleitner T,Alvarez JI,Rad R,Korn T,Hemmer B,Quintana FJ,Rothhammer V
15-5773-82 was used in Flow cytometry/Cell sorting to suggest the glial PD-L1/PD-1 axis as a potential therapeutic target for both acute and progressive MS stages.
Sat Sep 09 00:00:00 EDT 2023
Immunotherapy targeting plasma ASM is protective in a mouse model of Alzheimer's disease.
Nature communications
Choi BJ,Park MH,Park KH,Han WH,Yoon HJ,Jung HY,Hong JY,Chowdhury MR,Kim KY,Lee J,Song IS,Pang M,Choi MK,Gulbins E,Reichel M,Kornhuber J,Hong CW,Kim C,Kim SH,Schuchman EH,Jin HK,Bae JS
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Mar 24 00:00:00 EDT 2023
Crosstalk between microbiome, regulatory T cells and HCA2 orchestrates the inflammatory response in a murine psoriasis model.
Frontiers in immunology
Schwarz A,Philippsen R,Piticchio SG,Hartmann JN,Häsler R,Rose-John S,Schwarz T
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Mar 27 00:00:00 EDT 2023
SARS-CoV-2 spike protein promotes inflammatory cytokine activation and aggravates rheumatoid arthritis.
Cell communication and signaling : CCS
Lee AR,Woo JS,Lee SY,Lee YS,Jung J,Lee CR,Park SH,Cho ML
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu Mar 02 00:00:00 EST 2023
IFN-γ signature enables selection of neoadjuvant treatment in patients with stage III melanoma.
The Journal of experimental medicine
Reijers ILM,Rao D,Versluis JM,Menzies AM,Dimitriadis P,Wouters MW,Spillane AJ,Klop WMC,Broeks A,Bosch LJW,Lopez-Yurda M,van Houdt WJ,Rawson RV,Grijpink-Ongering LG,Gonzalez M,Cornelissen S,Bouwman J,Sanders J,Plasmeijer E,Elshot YS,Scolyer RA,van de Wiel BA,Peeper DS,van Akkooi ACJ,Long GV,Blank CU
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2023
Multiparametric flow cytometry to characterize vaccine-induced polyfunctional T cell responses and T cell/NK cell exhaustion and memory phenotypes in mouse immuno-oncology models.
Frontiers in immunology
Moi D,Zeng B,Minnie SA,Bhatt R,Wood J,Sester DP,Mazzieri R,Dolcetti R
15-5773-82 was used in Flow cytometry/Cell sorting to report the development and application of two 21-color flow cytometry panels allowing a comprehensive characterization of T cell and natural killer cell exhaustion and memory phenotypes in mice with a particular focus on preclinical cancer models.
Tue Apr 25 00:00:00 EDT 2023
TRAF6 controls T cell homeostasis by maintaining the equilibrium of MALT1 scaffolding and protease functions.
Frontiers in immunology
O'Neill TJ,Gewies A,Seeholzer T,Krappmann D
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Feb 13 00:00:00 EST 2023
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
Aiolos represses CD4+ T cell cytotoxic programming via reciprocal regulation of TFH transcription factors and IL-2 sensitivity.
Nature communications
Read KA,Jones DM,Pokhrel S,Hales EDS,Varkey A,Tuazon JA,Eisele CD,Abdouni O,Saadey A,Leonard MR,Warren RT,Powell MD,Boss JM,Hemann EA,Yount JS,Xin G,Ghoneim HE,Lio CJ,Freud AG,Collins PL,Oestreich KJ
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Mar 24 00:00:00 EDT 2023
miR-126 ameliorates multiple organ dysfunction in septic rats by regulating the differentiation of Th17/Treg.
Molecular biology reports
Zou Q,Liu C,Hu N,Wang W,Wang H
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2022
Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity.
Cancer cell
Chryplewicz A,Scotton J,Tichet M,Zomer A,Shchors K,Joyce JA,Homicsko K,Hanahan D
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Oct 10 00:00:00 EDT 2022
Twelve-week high-fat diet for improving adverse ventricular remodeling post-myocardial infarction by alleviating local inflammation.
Annals of translational medicine
Yang J,Mai B,Su Y,Liang S,Su Z,Chen Y,Xie S
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Sat Oct 01 00:00:00 EDT 2022
Protocol to assess cell-intrinsic regulatory mechanisms using an ex vivo murine T cell polarization and co-culture system.
STAR protocols
Ma S,Hernandez JE,Huang WJM
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Sep 16 00:00:00 EDT 2022
Nucleolin Therapeutic Targeting Decreases Pancreatic Cancer Immunosuppression.
Cancers
Ponzo M,Debesset A,Cossutta M,Chalabi-Dchar M,Houppe C,Pilon C,Nicolas-Boluda A,Meunier S,Raineri F,Thiolat A,Nicolle R,Maione F,Brundu S,Cojocaru CF,Bouvet P,Bousquet C,Gazeau F,Tournigand C,Courty J,Giraudo E,Cohen JL,Cascone I
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Aug 31 00:00:00 EDT 2022
Lactate induces metabolic and epigenetic reprogramming of pro-inflammatory Th17 cells.
EMBO reports
Lopez Krol A,Nehring HP,Krause FF,Wempe A,Raifer H,Nist A,Stiewe T,Bertrams W,Schmeck B,Luu M,Leister H,Chung HR,Bauer UM,Adhikary T,Visekruna A
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Dec 06 00:00:00 EST 2022
Impaired Treg-DC interactions contribute to autoimmunity in leukocyte adhesion deficiency type 1.
JCI insight
Klaus T,Wilson AS,Vicari E,Hadaschik E,Klein M,Helbich SSC,Kamenjarin N,Hodapp K,Schunke J,Haist M,Butsch F,Probst HC,Enk AH,Mahnke K,Waisman A,Bednarczyk M,Bros M,Bopp T,Grabbe S
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu Dec 22 00:00:00 EST 2022
Pharmacologic Tumor PDL1 Depletion with Cefepime or Ceftazidime Promotes DNA Damage and Sensitivity to DNA-Damaging Agents.
International journal of molecular sciences
Murray C,Galvan E,Ontiveros C,Deng Y,Bai H,Padron AS,Hinchee-Rodriguez K,Garcia MG,Kornepati A,Conejo-Garcia J,Curiel TJ
15-5773-82 was used in Flow cytometry/Cell sorting to highlight the rapidly translated potential for PDL1-depleting drugs to inhibit tumor-intrinsic PDL1 signals and improve DNA-damaging agents and immunotherapy efficacy.
Wed May 04 00:00:00 EDT 2022
Galectin-9 Mediates the Therapeutic Effect of Mesenchymal Stem Cells on Experimental Endotoxemia.
Frontiers in cell and developmental biology
Zhao Y,Yu D,Wang H,Jin W,Li X,Hu Y,Qin Y,Kong D,Li G,Ellen A,Wang H
15-5773-82 was used in Flow cytometry/Cell sorting to reveal that the optimized immunoregulatory effect of MSCs is strongly correlated with Gal-9 high expression, which provides a novel idea for the investigation of MSC immunomodulatory mechanisms and offers a potential strategy for the treatment of endotoxemia in clinical settings.
Wed Mar 09 00:00:00 EST 2022
Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections.
Immunity
Harb H,Benamar M,Lai PS,Contini P,Griffith JW,Crestani E,Schmitz-Abe K,Chen Q,Fong J,Marri L,Filaci G,Del Zotto G,Pishesha N,Kolifrath S,Broggi A,Ghosh S,Gelmez MY,Oktelik FB,Cetin EA,Kiykim A,Kose M,Wang Z,Cui Y,Yu XG,Li JZ,Berra L,Stephen-Victor E,Charbonnier LM,Zanoni I,Ploegh H,Deniz G,De Palma R,Chatila TA
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Jun 08 00:00:00 EDT 2021
Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility.
The Journal of experimental medicine
Wirasinha RC,Davies AR,Srivastava M,Sheridan JM,Sng XYX,Delmonte OM,Dobbs K,Loh KL,Miosge LA,Lee CE,Chand R,Chan A,Yap JY,Keller MD,Chen K,Rossjohn J,La Gruta NL,Vinuesa CG,Reid HH,Lionakis MS,Notarangelo LD,Gray DHD,Goodnow CC,Cook MC,Daley SR
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Ubiquitin-specific peptidase 18 regulates the differentiation and function of Treg cells.
Genes & diseases
Yang L,Jing Y,Kang D,Jiang P,Li N,Zhou X,Chen Y,Westerberg LS,Liu C
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Thymic atrophy creates holes in Treg-mediated immuno-regulation via impairment of an antigen-specific clone.
Immunology
Thomas R,Oh J,Wang W,Su DM
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Sun Aug 01 00:00:00 EDT 2021
Romidepsin (FK228) regulates the expression of the immune checkpoint ligand PD-L1 and suppresses cellular immune functions in colon cancer.
Cancer immunology, immunotherapy : CII
Shi Y,Fu Y,Zhang X,Zhao G,Yao Y,Guo Y,Ma G,Bai S,Li H
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Sirt6 Regulates the Development of Medullary Thymic Epithelial Cells and Contributes to the Establishment of Central Immune Tolerance.
Frontiers in cell and developmental biology
Zhang Q,Liang Z,Zhang J,Lei T,Dong X,Su H,Chen Y,Zhang Z,Tan L,Zhao Y
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Apr 21 00:00:00 EDT 2021
Transfer of Th17 from Adult Spontaneous Hypertensive Rats Accelerates Development of Hypertension in Juvenile Spontaneous Hypertensive Rats.
BioMed research international
Kim JY,Lee E,Koo S,Kim CW,Kim I
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue May 25 00:00:00 EDT 2021
Imbalance between T helper 1 and regulatory T cells plays a detrimental role in experimental Parkinson's disease in mice.
The Journal of international medical research
Li W,Luo Y,Xu H,Ma Q,Yao Q
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Intratumoral expression of interleukin 23 variants using oncolytic vaccinia virus elicit potent antitumor effects on multiple tumor models via tumor microenvironment modulation.
Theranostics
Chen L,Chen H,Ye J,Ge Y,Wang H,Dai E,Ren J,Liu W,Ma C,Ju S,Guo ZS,Liu Z,Bartlett DL
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Aug 04 00:00:00 EDT 2021
Alphavirus-Driven Interferon Gamma (IFNg) Expression Inhibits Tumor Growth in Orthotopic 4T1 Breast Cancer Model.
Vaccines
Trofimova O,Korotkaja K,Skrastina D,Jansons J,Spunde K,Isaguliants M,Zajakina A
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Oct 27 00:00:00 EDT 2021
IDO1 Expression in Ovarian Cancer Induces PD-1 in T Cells via Aryl Hydrocarbon Receptor Activation.
Frontiers in immunology
Amobi-McCloud A,Muthuswamy R,Battaglia S,Yu H,Liu T,Wang J,Putluri V,Singh PK,Qian F,Huang RY,Putluri N,Tsuji T,Lugade AA,Liu S,Odunsi K
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Oct 29 00:00:00 EDT 2021
The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia.
Journal of neuroinflammation
Malone K,Diaz Diaz AC,Shearer JA,Moore AC,Waeber C
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Sat Jan 30 00:00:00 EST 2021
ILC3s control airway inflammation by limiting T cell responses to allergens and microbes.
Cell reports
Teng F,Tachó-Piñot R,Sung B,Farber DL,Worgall S,Hammad H,Lambrecht BN,Hepworth MR,Sonnenberg GF
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Nov 23 00:00:00 EST 2021
Dual Role of Interleukin-10 in Murine NZB/W F1 Lupus.
International journal of molecular sciences
Amend A,Wickli N,Schäfer AL,Sprenger DTL,Manz RA,Voll RE,Chevalier N
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Jan 29 00:00:00 EST 2021
Aging-associated deficit in CCR7 is linked to worsened glymphatic function, cognition, neuroinflammation, and β-amyloid pathology.
Science advances
Da Mesquita S,Herz J,Wall M,Dykstra T,de Lima KA,Norris GT,Dabhi N,Kennedy T,Baker W,Kipnis J
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota.
Theranostics
Tong L,Hao H,Zhang Z,Lv Y,Liang X,Liu Q,Liu T,Gong P,Zhang L,Cao F,Pastorin G,Lee CN,Chen X,Wang JW,Yi H
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Jan 28 00:00:00 EST 2022
Rodent Models of Spondyloarthritis Have Decreased White and Bone Marrow Adipose Tissue Depots.
Frontiers in immunology
Furesi G,Fert I,Beaufrère M,Araujo LM,Glatigny S,Baschant U,von Bonin M,Hofbauer LC,Horwood NJ,Breban M,Rauner M
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Oct 25 00:00:00 EDT 2021
A Biological Circuit Involving Mef2c, Mef2d, and Hdac9 Controls the Immunosuppressive Functions of CD4+Foxp3+ T-Regulatory Cells.
Frontiers in immunology
Di Giorgio E,Wang L,Xiong Y,Christensen LM,Akimova T,Han R,Samanta A,Trevisanut M,Brancolini C,Beier UH,Hancock WW
15-5773-82 was used in Flow Cytometry to report that as with Mef2d, the deletion of Mef2c in Tregs switches off the expression of Il10 and Icos and leads to enhanced antitumor immunity in syngeneic models of lung cancer.
Fri Dec 17 00:00:00 EST 2021
Astrocyte-Derived Pleiotrophin Mitigates Late-Stage Autoimmune CNS Inflammation.
Frontiers in immunology
Linnerbauer M,Lößlein L,Farrenkopf D,Vandrey O,Tsaktanis T,Naumann U,Rothhammer V
15-5773-82 was used in Flow Cytometry to demonstrate in vivo that astrocyte-derived pleiotrophin is critical for the recovery phase of autoimmune encephalomyelitis and limits chronic CNS inflammation.
Mon Feb 14 00:00:00 EST 2022
Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis.
Frontiers in immunology
Yang P,Tian H,Zou YR,Chambon P,Ichinose H,Honig G,Diamond B,Kim SJ
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Cooperation Between Distinct Cancer Driver Genes Underlies Intertumor Heterogeneity in Hepatocellular Carcinoma.
Gastroenterology
Molina-Sánchez P,Ruiz de Galarreta M,Yao MA,Lindblad KE,Bresnahan E,Bitterman E,Martin TC,Rubenstein T,Nie K,Golas J,Choudhary S,Bárcena-Varela M,Elmas A,Miguela V,Ding Y,Kan Z,Grinspan LT,Huang KL,Parsons RE,Shields DJ,Rollins RA,Lujambio A
15-5773 was used in Flow cytometry/Cell sorting to establish a novel collection of hepatocellular carcinoma mouse models that captured human hepatocellular carcinoma diversity.
Tue Dec 01 00:00:00 EST 2020
Protein arginine methyltransferase 5 promotes cholesterol biosynthesis-mediated Th17 responses and autoimmunity.
The Journal of clinical investigation
Webb LM,Sengupta S,Edell C,Piedra-Quintero ZL,Amici SA,Miranda JN,Bevins M,Kennemer A,Laliotis G,Tsichlis PN,Guerau-de-Arellano M
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
MEF2D sustains activation of effector Foxp3+ Tregs during transplant survival and anticancer immunity.
The Journal of clinical investigation
Di Giorgio E,Wang L,Xiong Y,Akimova T,Christensen LM,Han R,Samanta A,Trevisanut M,Bhatti TR,Beier UH,Hancock WW
15-5773 was used in Flow cytometry/Cell sorting to study the role played by MEF2D in sustaining effector Foxp3+ Treg functions without abrogating their basal actions suggests its suitability for drug discovery efforts in cancer therapy.
Tue Dec 01 00:00:00 EST 2020
Protection of Batf3-deficient mice from experimental cerebral malaria correlates with impaired cytotoxic T-cell responses and immune regulation.
Immunology
Kuehlwein JM,Borsche M,Korir PJ,Risch F,Mueller AK,Hübner MP,Hildner K,Hoerauf A,Dunay IR,Schumak B
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
Activated pathogenic Th17 lymphocytes induce hypertension following high-fructose intake in Dahl salt-sensitive but not Dahl salt-resistant rats.
Disease models & mechanisms
Lee E,Kim N,Kang J,Yoon S,Lee HA,Jung H,Kim SH,Kim I
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed May 27 00:00:00 EDT 2020
Enhanced alleviation of aGVHD by TGF-β1-modified mesenchymal stem cells in mice through shifting MΦ into M2 phenotype and promoting the differentiation of Treg cells.
Journal of cellular and molecular medicine
Wu R,Liu C,Deng X,Chen L,Hao S,Ma L
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2020
A novel inhibitory role of microRNA-224 in particulate matter 2.5-induced asthmatic mice by inhibiting TLR2.
Journal of cellular and molecular medicine
Li P,Wang J,Guo F,Zheng B,Zhang X
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2020
A Phase I, Dose Escalation, Single Dose Trial of Oral Attenuated Salmonella typhimurium Containing Human IL-2 in Patients With Metastatic Gastrointestinal Cancers.
Journal of immunotherapy (Hagerstown, Md. : 1997)
Gniadek TJ,Augustin L,Schottel J,Leonard A,Saltzman D,Greeno E,Batist G
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2020
HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment.
Journal of Cancer
Kim YD,Park SM,Ha HC,Lee AR,Won H,Cha H,Cho S,Cho JM
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
Japanese Kampo Medicine Juzentaihoto Enhances Antitumor Immunity in CD1d-/- Mice Lacking NKT Cells.
Integrative cancer therapies
Takaku S,Shimizu M,Takahashi H
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Mar 23 00:00:00 EDT 2020
Horses with equine recurrent uveitis have an activated CD4+ T-cell phenotype that can be modulated by mesenchymal stem cells in vitro.
Veterinary ophthalmology
Saldinger LK,Nelson SG,Bellone RR,Lassaline M,Mack M,Walker NJ,Borjesson DL
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2020
Dietary Glucose Consumption Promotes RALDH Activity in Small Intestinal CD103+CD11b+ Dendritic Cells.
Frontiers in immunology
Ko HJ,Hong SW,Verma R,Jung J,Lee M,Kim N,Kim D,Surh CD,Kim KS,Rudra D,Im SH
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Apr 19 00:00:00 EDT 2021
Lysosomal Acid Lipase Is Required for Donor T Cells to Induce Graft-versus-Host Disease.
Cell reports
Nguyen HD,Ticer T,Bastian D,Kuril S,Li H,Du H,Yan C,Yu XZ
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Oct 27 00:00:00 EDT 2020
Assessing IL-2-Induced STAT5 Phosphorylation in Fixed, Permeabilized Foxp3+ Treg Cells by Multiparameter Flow Cytometry.
STAR protocols
Li C,Park JH
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Dec 18 00:00:00 EST 2020
Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5.
Cell reports
Vanderleyden I,Fra-Bido SC,Innocentin S,Stebegg M,Okkenhaug H,Evans-Bailey N,Pierson W,Denton AE,Linterman MA
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Jan 21 00:00:00 EST 2020
FOXD3 Regulates VISTA Expression in Melanoma.
Cell reports
Rosenbaum SR,Knecht M,Mollaee M,Zhong Z,Erkes DA,McCue PA,Chervoneva I,Berger AC,Lo JA,Fisher DE,Gershenwald JE,Davies MA,Purwin TJ,Aplin AE
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Jan 14 00:00:00 EST 2020
Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy.
Nature communications
Baumann D,Hägele T,Mochayedi J,Drebant J,Vent C,Blobner S,Noll JH,Nickel I,Schumacher C,Boos SL,Daniel AS,Wendler S,Volkmar M,Strobel O,Offringa R
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses.
Scientific reports
Hrdý J,Alard J,Couturier-Maillard A,Boulard O,Boutillier D,Delacre M,Lapadatescu C,Cesaro A,Blanc P,Pot B,Ryffel B,Chamaillard M,Grangette C
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Mar 24 00:00:00 EDT 2020
Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses.
Scientific reports
Hrdý J,Alard J,Couturier-Maillard A,Boulard O,Boutillier D,Delacre M,Lapadatescu C,Cesaro A,Blanc P,Pot B,Ryffel B,Chamaillard M,Grangette C
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Mar 24 00:00:00 EDT 2020
Donor bone-marrow CXCR4+ Foxp3+ T-regulatory cells are essential for costimulation blockade-induced long-term survival of murine limb transplants.
Scientific reports
Wang L,Wang Z,Han R,Samanta A,Ge G,Levin LS,Levine MH,Hancock WW
15-5773 was used in Flow cytometry/Cell sorting to tested whether peri-transplant costimulation blockade could prolong VCA survival and required donor bone-marrow cells, given that bone-marrow might promote graft immunogenicity or graft-versus-host disease.
Tue Jun 09 00:00:00 EDT 2020
Donor bone-marrow CXCR4+ Foxp3+ T-regulatory cells are essential for costimulation blockade-induced long-term survival of murine limb transplants.
Scientific reports
Wang L,Wang Z,Han R,Samanta A,Ge G,Levin LS,Levine MH,Hancock WW
15-5773 was used in Flow cytometry/Cell sorting to tested whether peri-transplant costimulation blockade could prolong VCA survival and required donor bone-marrow cells, given that bone-marrow might promote graft immunogenicity or graft-versus-host disease.
Tue Jun 09 00:00:00 EDT 2020
Host deficiency in ephrin-A1 inhibits breast cancer metastasis.
F1000Research
Shiuan E,Inala A,Wang S,Song W,Youngblood V,Chen J,Brantley-Sieders DM
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Respiratory Syncytial Virus Infection Reduces Kynurenic Acid Production and Reverses Th17/Treg Balance by Modulating Indoleamine 2,3-Dioxygenase (IDO) Molecules in Plasmacytoid Dendritic Cells.
Medical science monitor : international medical journal of experimental and clinical research
Jin L,Hu Q,Hu Y,Chen Z,Liao W
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Dec 02 00:00:00 EST 2020
Treatment of mice with a ligand binding blocking anti-CD28 monoclonal antibody improves healing after myocardial infarction.
PloS one
Gladow N,Hollmann C,Ramos G,Frantz S,Kerkau T,Beyersdorf N,Hofmann U
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Jul 06 00:00:00 EDT 2020
3'-Sialyllactose prebiotics prevents skin inflammation via regulatory T cell differentiation in atopic dermatitis mouse models.
Scientific reports
Kang LJ,Oh E,Cho C,Kwon H,Lee CG,Jeon J,Lee H,Choi S,Han SJ,Nam J,Song CU,Jung H,Kim HY,Park EJ,Choi EJ,Kim J,Eyun SI,Yang S
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Mar 27 00:00:00 EDT 2020
Ginsenoside RG1 enhances the paracrine effects of bone marrow-derived mesenchymal stem cells on radiation induced intestinal injury.
Aging
Luo Y,Wang B,Liu J,Ma F,Luo D,Zheng Z,Lu Q,Zhou W,Zheng Y,Zhang C,Wang Q,Sha W,Chen H
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu Dec 03 00:00:00 EST 2020
Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Restructures the Immune Contexture to Improve Checkpoint Blockade Efficacy.
Biomedicines
Ebelt ND,Zuniga E,Marzagalli M,Zamloot V,Blazar BR,Salgia R,Manuel ER
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine.
Nature communications
Campesato LF,Budhu S,Tchaicha J,Weng CH,Gigoux M,Cohen IJ,Redmond D,Mangarin L,Pourpe S,Liu C,Zappasodi R,Zamarin D,Cavanaugh J,Castro AC,Manfredi MG,McGovern K,Merghoub T,Wolchok JD
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Aug 11 00:00:00 EDT 2020
A micropeptide encoded by lncRNA MIR155HG suppresses autoimmune inflammation via modulating antigen presentation.
Science advances
Niu L,Lou F,Sun Y,Sun L,Cai X,Liu Z,Zhou H,Wang H,Wang Z,Bai J,Yin Q,Zhang J,Chen L,Peng D,Xu Z,Gao Y,Tang S,Fan L,Wang H
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Axenic Caenorhabditis elegans antigen protects against development of type-1 diabetes in NOD mice.
Journal of translational autoimmunity
Jackson-Thompson BM,Torrero M,Mitre BK,Long J,Packiam M,Mitre E
15-5773-82 was used in Flow Cytometry to investigate whether soluble antigens obtained from Caenorhabditis elegans can confer protection against inflammatory disease.
Mon Sep 28 00:00:00 EDT 2020
Axenic Caenorhabditis elegans antigen protects against development of type-1 diabetes in NOD mice.
Journal of translational autoimmunity
Jackson-Thompson BM,Torrero M,Mitre BK,Long J,Packiam M,Mitre E
15-5773-82 was used in Flow Cytometry to investigate whether soluble antigens obtained from Caenorhabditis elegans can confer protection against inflammatory disease.
Mon Sep 28 00:00:00 EDT 2020
Compartmentalized gut lymph node drainage dictates adaptive immune responses.
Nature
Esterházy D,Canesso MCC,Mesin L,Muller PA,de Castro TBR,Lockhart A,ElJalby M,Faria AMC,Mucida D
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed May 01 00:00:00 EDT 2019
Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy.
Cell research
Zhang Y,Du X,Liu M,Tang F,Zhang P,Ai C,Fields JK,Sundberg EJ,Latinovic OS,Devenport M,Zheng P,Liu Y
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu Aug 01 00:00:00 EDT 2019
Consequences of early postnatal lipopolysaccharide exposure on developing lungs in mice.
American journal of physiology. Lung cellular and molecular physiology
Shrestha AK,Bettini ML,Menon RT,Gopal VYN,Huang S,Edwards DP,Pammi M,Barrios R,Shivanna B
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2019
Characterization of immune cell subtypes in three commonly used mouse strains reveals gender and strain-specific variations.
Laboratory investigation; a journal of technical methods and pathology
Hensel JA,Khattar V,Ashton R,Ponnazhagan S
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2019
Interleukin 10 Gene-Modified Bone Marrow-Derived Dendritic Cells Attenuate Liver Fibrosis in Mice by Inducing Regulatory T Cells and Inhibiting the TGF-β/Smad Signaling Pathway.
Mediators of inflammation
Xu Y,Tang X,Yang M,Zhang S,Li S,Chen Y,Liu M,Guo Y,Lu M
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Jun 11 00:00:00 EDT 2019
Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.
Anti-cancer drugs
Zhou Y,Fu C,Kong Y,Pan D,Wang Y,Huang S,Li Z,Ning Z,Lu X,Shan S,Xin L
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
Mast Cells Are Mediators of Fibrosis and Effector Cell Recruitment in Dermal Chronic Graft-vs.-Host Disease.
Frontiers in immunology
Strattan E,Palaniyandi S,Kumari R,Du J,Hakim N,Huang T,Kesler MV,Jennings CD,Sturgill JL,Hildebrandt GC
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Nov 17 00:00:00 EST 2020
Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells.
Frontiers in immunology
Xu J,Pei S,Wang Y,Liu J,Qian Y,Huang M,Zhang Y,Xiao Y
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Oct 14 00:00:00 EDT 2020
Loss of TET2 and TET3 in regulatory T cells unleashes effector function.
Nature communications
Yue X,Lio CJ,Samaniego-Castruita D,Li X,Rao A
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed May 01 00:00:00 EDT 2019
Bacteroides fragilis polysaccharide A induces IL-10 secreting B and T cells that prevent viral encephalitis.
Nature communications
Ramakrishna C,Kujawski M,Chu H,Li L,Mazmanian SK,Cantin EM
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue May 14 00:00:00 EDT 2019
Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth.
Nature communications
Kusano T,Ehirchiou D,Matsumura T,Chobaz V,Nasi S,Castelblanco M,So A,Lavanchy C,Acha-Orbea H,Nishino T,Okamoto K,Busso N
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Oct 28 00:00:00 EDT 2019
Systemic inhibition of tissue-nonspecific alkaline phosphatase alters the brain-immune axis in experimental sepsis.
Scientific reports
Brichacek AL,Benkovic SA,Chakraborty S,Nwafor DC,Wang W,Jun S,Dakhlallah D,Geldenhuys WJ,Pinkerton AB,Millán JL,Brown CM
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Dec 11 00:00:00 EST 2019
A20 as an immune tolerance factor can determine islet transplant outcomes.
JCI insight
Zammit NW,Walters SN,Seeberger KL,O'Connell PJ,Korbutt GS,Grey ST
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2019
Anti-IL-6 eluting immunomodulatory biomaterials prolong skin allograft survival.
Scientific reports
Uehara M,Li X,Sheikhi A,Zandi N,Walker B,Saleh B,Banouni N,Jiang L,Ordikhani F,Dai L,Yonar M,Vohra I,Kasinath V,Orgill DP,Khademhosseini A,Annabi N,Abdi R
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu Apr 25 00:00:00 EDT 2019
Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function.
Cell reports
Fu Z,Ye J,Dean JW,Bostick JW,Weinberg SE,Xiong L,Oliff KN,Chen ZE,Avram D,Chandel NS,Zhou L
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Jul 02 00:00:00 EDT 2019
Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation.
Cell reports
Ciecko AE,Foda B,Barr JY,Ramanathan S,Atkinson MA,Serreze DV,Geurts AM,Lieberman SM,Chen YG
15-5773-82 was used in Flow Cytometry to reveal that IL-27 contributes to autoimmunity in NOD mice through multiple mechanisms and provides substantial evidence to support its pathogenic role in human T1D.
Tue Dec 03 00:00:00 EST 2019
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
Commensals Suppress Intestinal Epithelial Cell Retinoic Acid Synthesis to Regulate Interleukin-22 Activity and Prevent Microbial Dysbiosis.
Immunity
Grizotte-Lake M,Zhong G,Duncan K,Kirkwood J,Iyer N,Smolenski I,Isoherranen N,Vaishnava S
15-5773 was used in Flow cytometry/Cell sorting to define a regulatory circuit wherein bacterial regulation of IEC-intrinsic RA synthesis protects microbial communities in the gut from excessive immune activity, achieving a balance that prevents colonization by enteric pathogens.
Tue Dec 18 00:00:00 EST 2018
PPARγ deacetylation dissociates thiazolidinedione's metabolic benefits from its adverse effects.
The Journal of clinical investigation
Kraakman MJ,Liu Q,Postigo-Fernandez J,Ji R,Kon N,Larrea D,Namwanje M,Fan L,Chan M,Area-Gomez E,Fu W,Creusot RJ,Qiang L
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Jun 01 00:00:00 EDT 2018
Nox2 in regulatory T cells promotes angiotensin II-induced cardiovascular remodeling.
The Journal of clinical investigation
Emmerson A,Trevelin SC,Mongue-Din H,Becker PD,Ortiz C,Smyth LA,Peng Q,Elgueta R,Sawyer G,Ivetic A,Lechler RI,Lombardi G,Shah AM
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Jul 02 00:00:00 EDT 2018
MTOR signaling is essential for the development of thymic epithelial cells and the induction of central immune tolerance.
Autophagy
Liang Z,Zhang L,Su H,Luan R,Na N,Sun L,Zhao Y,Zhang X,Zhang Q,Li J,Zhang L,Zhao Y
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Mar 22 00:00:00 EDT 2019
Pre-existing Immunity to Oncolytic Virus Potentiates Its Immunotherapeutic Efficacy.
Molecular therapy : the journal of the American Society of Gene Therapy
Ricca JM,Oseledchyk A,Walther T,Liu C,Mangarin L,Merghoub T,Wolchok JD,Zamarin D
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Apr 04 00:00:00 EDT 2018
Bryostatin-1 alleviates experimental multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America
Kornberg MD,Smith MD,Shirazi HA,Calabresi PA,Snyder SH,Kim PM
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Feb 27 00:00:00 EST 2018
Cambogin suppresses dextran sulphate sodium-induced colitis by enhancing Treg cell stability and function.
British journal of pharmacology
Lu Y,Kim NM,Jiang YW,Zhang H,Zheng D,Zhu FX,Liang R,Li B,Xu HX
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
Tolerogenic Nanoparticles Induce Antigen-Specific Regulatory T Cells and Provide Therapeutic Efficacy and Transferrable Tolerance against Experimental Autoimmune Encephalomyelitis.
Frontiers in immunology
LaMothe RA,Kolte PN,Vo T,Ferrari JD,Gelsinger TC,Wong J,Chan VT,Ahmed S,Srinivasan A,Deitemeyer P,Maldonado RA,Kishimoto TK
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu Mar 21 00:00:00 EDT 2019
CD4+ T Cell Fate Decisions Are Stochastic, Precede Cell Division, Depend on GITR Co-Stimulation, and Are Associated With Uropodium Development.
Frontiers in immunology
Cobbold SP,Adams E,Howie D,Waldmann H
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Jan 31 00:00:00 EST 2022
Gut Microbiota Confers Resistance of Albino Oxford Rats to the Induction of Experimental Autoimmune Encephalomyelitis.
Frontiers in immunology
Stanisavljević S,Dinić M,Jevtić B,Đedović N,Momčilović M,Đokić J,Golić N,Mostarica Stojković M,Miljković Đ
15-5773 was used in Flow cytometry/Cell sorting to study the effects of modulating the gut microbiota of albino oxford rats using antibiotics.
Mon Jul 01 00:00:00 EDT 2019
Indirect presentation in the thymus limits naive and regulatory T-cell differentiation by promoting deletion of self-reactive thymocytes.
Immunology
Yap JY,Wirasinha RC,Chan A,Howard DR,Goodnow CC,Daley SR
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Sun Jul 01 00:00:00 EDT 2018
TRPM2 Exacerbates Central Nervous System Inflammation in Experimental Autoimmune Encephalomyelitis by Increasing Production of CXCL2 Chemokines.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Tsutsui M,Hirase R,Miyamura S,Nagayasu K,Nakagawa T,Mori Y,Shirakawa H,Kaneko S
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Sep 26 00:00:00 EDT 2018
PDL-1 Blockade Prevents T Cell Exhaustion, Inhibits Autophagy, and Promotes Clearance of Leishmania donovani.
Infection and immunity
Habib S,El Andaloussi A,Elmasry K,Handoussa A,Azab M,Elsawey A,Al-Hendy A,Ismail N
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Jun 01 00:00:00 EDT 2018
Immunological effects of a low-dose cytarabine, aclarubicin and granulocyte-colony stimulating factor priming regimen on a mouse leukemia model.
Oncology letters
Chen J,Yang N,Liu H,Yao H,Wang J,Yang Y,Zhang W
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
Combined treatment with simvastatin and rapamycin attenuates cardiac allograft rejection through the regulation of T helper 17 and regulatory T cells.
Experimental and therapeutic medicine
Liu Y,Sun L,Chen W,Chuai J,Shang Y,Zhang D,Fu B,Tian H,Jiang S
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu Feb 01 00:00:00 EST 2018
Assessment of tumor growth factor-β1 neutralizing antibody in the treatment of allergic rhinitis and asthma.
Experimental and therapeutic medicine
Wei Y,Zhang Z,Wang F,Zhou S
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype.
Nature communications
Chen D,Xie J,Fiskesund R,Dong W,Liang X,Lv J,Jin X,Liu J,Mo S,Zhang T,Cheng F,Zhou Y,Zhang H,Tang K,Ma J,Liu Y,Huang B
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Feb 28 00:00:00 EST 2018
Lymphotoxin α fine-tunes T cell clonal deletion by regulating thymic entry of antigen-presenting cells.
Nature communications
Lopes N,Charaix J,Cédile O,Sergé A,Irla M
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Mar 28 00:00:00 EDT 2018
Blimp-1 Functions as a Molecular Switch to Prevent Inflammatory Activity in Foxp3+RORγt+ Regulatory T Cells.
Cell reports
Ogawa C,Bankoti R,Nguyen T,Hassanzadeh-Kiabi N,Nadeau S,Porritt RA,Couse M,Fan X,Dhall D,Eberl G,Ohnmacht C,Martins GA
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Oct 02 00:00:00 EDT 2018
Neuregulin-1 elicits a regulatory immune response following traumatic spinal cord injury.
Journal of neuroinflammation
Alizadeh A,Santhosh KT,Kataria H,Gounni AS,Karimi-Abdolrezaee S
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Feb 21 00:00:00 EST 2018
Loss of Sirt2 increases and prolongs a caerulein-induced pancreatitis permissive phenotype and induces spontaneous oncogenic Kras mutations in mice.
Scientific reports
Quan S,Principe DR,Dean AE,Park SH,Grippo PJ,Gius D,Horikoshi N
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Nov 07 00:00:00 EST 2018
Modifying the cancer-immune set point using vaccinia virus expressing re-designed interleukin-2.
Nature communications
Liu Z,Ge Y,Wang H,Ma C,Feist M,Ju S,Guo ZS,Bartlett DL
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu Nov 08 00:00:00 EST 2018
REV-ERBα Regulates TH17 Cell Development and Autoimmunity.
Cell reports
Amir M,Chaudhari S,Wang R,Campbell S,Mosure SA,Chopp LB,Lu Q,Shang J,Pelletier OB,He Y,Doebelin C,Cameron MD,Kojetin DJ,Kamenecka TM,Solt LA
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Dec 26 00:00:00 EST 2018
Topical Application of TGF-β-Activating Peptide, KRFK, Prevents Inflammatory Manifestations in the TSP-1-Deficient Mouse Model of Chronic Ocular Inflammation.
International journal of molecular sciences
Soriano-Romaní L,Contreras-Ruiz L,López-García A,Diebold Y,Masli S
15-5773 was used in Flow cytometry/Cell sorting to identify the KRFK peptide as a novel therapeutic option to prevent the development of chronic inflammatory manifestations of the ocular surface.
Thu Dec 20 00:00:00 EST 2018
IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells.
Nature communications
Hsieh WC,Hsu TS,Chang YJ,Lai MZ
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Jan 31 00:00:00 EST 2018
High dietary salt intake correlates with modulated Th17-Treg cell balance resulting in enhanced bone loss and impaired bone-microarchitecture in male mice.
Scientific reports
Dar HY,Singh A,Shukla P,Anupam R,Mondal RK,Mishra PK,Srivastava RK
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Feb 06 00:00:00 EST 2018
An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression.
Cancer cell
Palazon A,Tyrakis PA,Macias D,Veliça P,Rundqvist H,Fitzpatrick S,Vojnovic N,Phan AT,Loman N,Hedenfalk I,Hatschek T,Lövrot J,Foukakis T,Goldrath AW,Bergh J,Johnson RS
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Nov 13 00:00:00 EST 2017
Autoreactive T Cells and Chronic Fungal Infection Drive Esophageal Carcinogenesis.
Cell host & microbe
Zhu F,Willette-Brown J,Song NY,Lomada D,Song Y,Xue L,Gray Z,Zhao Z,Davis SR,Sun Z,Zhang P,Wu X,Zhan Q,Richie ER,Hu Y
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Apr 12 00:00:00 EDT 2017
Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvironment.
The Journal of clinical investigation
Wang YT,Chen J,Chang CW,Jen J,Huang TY,Chen CM,Shen R,Liang SY,Cheng IC,Yang SC,Lai WW,Cheng KH,Hsieh TS,Lai MZ,Cheng HC,Wang YC,Chen RH
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2017
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
The Journal of clinical investigation
Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Excessive expression of miR-27 impairs Treg-mediated immunological tolerance.
The Journal of clinical investigation
Cruz LO,Hashemifar SS,Wu CJ,Cho S,Nguyen DT,Lin LL,Khan AA,Lu LF
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
PTEN drives Th17 cell differentiation by preventing IL-2 production.
The Journal of experimental medicine
Kim HS,Jang SW,Lee W,Kim K,Sohn H,Hwang SS,Lee GR
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Nov 06 00:00:00 EST 2017
IL-2 prevents deletion of developing T-regulatory cells in the thymus.
Cell death and differentiation
Hu DY,Wirasinha RC,Goodnow CC,Daley SR
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
A bidirectional association between the gut microbiota and CNS disease in a biphasic murine model of multiple sclerosis.
Gut microbes
Colpitts SL,Kasper EJ,Keever A,Liljenberg C,Kirby T,Magori K,Kasper LH,Ochoa-Repáraz J
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu Nov 02 00:00:00 EDT 2017
The Ox40/Ox40 Ligand Pathway Promotes Pathogenic Th Cell Responses, Plasmablast Accumulation, and Lupus Nephritis in NZB/W F1 Mice.
Journal of immunology (Baltimore, Md. : 1950)
Sitrin J,Suto E,Wuster A,Eastham-Anderson J,Kim JM,Austin CD,Lee WP,Behrens TW
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Aug 15 00:00:00 EDT 2017
Azacitidine Mitigates Graft-versus-Host Disease via Differential Effects on the Proliferation of T Effectors and Natural Regulatory T Cells In Vivo.
Journal of immunology (Baltimore, Md. : 1950)
Cooper ML,Choi J,Karpova D,Vij K,Ritchey J,Schroeder MA,DiPersio JF
15-5773 was used in Flow cytometry/Cell sorting to demonstrate that natural regulatory T cells are essential for azacitidine to fully protect against graft-versus-host disease and have important clinical implications for future clinical trials testing AzaC as a novel method of GvHD prophylaxis.
Mon May 01 00:00:00 EDT 2017
Dichloroacetate induces regulatory T-cell differentiation and suppresses Th17-cell differentiation by pyruvate dehydrogenase kinase-independent mechanism.
The Journal of pharmacy and pharmacology
Makita N,Ishiguro J,Suzuki K,Nara F
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
SH479, a Betulinic Acid Derivative, Ameliorates Experimental Autoimmune Encephalomyelitis by Regulating the T Helper 17/Regulatory T Cell Balance.
Molecular pharmacology
Li J,Jing J,Bai Y,Li Z,Xing R,Tan B,Ma X,Qiu WW,Du C,Du B,Yang F,Tang J,Siwko S,Liu M,Chen H,Luo J
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
Placenta‑derived mesenchymal stem cells improve airway hyperresponsiveness and inflammation in asthmatic rats by modulating the Th17/Treg balance.
Molecular medicine reports
Li Y,Li H,Cao Y,Wu F,Ma W,Wang Y,Sun S
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2017
Anti-CD20 monoclonal antibody combined with adenovirus vector-mediated IL-10 regulates spleen CD4+/CD8+ T cells and T-bet/GATA-3 expression in NOD mice.
Molecular medicine reports
Tang A,Li C,Chen Z,Li T
15-5773 was used in Flow cytometry/Cell sorting to suggest that anti-CD20 and IL-10 treatment in NOD mice can modulate the immune functions by up-regulating GATA-3 and IL-4 expression as well as down-regulating T-bet and IFN-γ expression.
Sun Oct 01 00:00:00 EDT 2017
B cells inhibit the antitumor immunity against an established murine fibrosarcoma.
Oncology letters
Maglioco A,Machuca DG,Badano MN,Nannini P,Camerano GV,Costa H,Meiss R,Ruggiero RA,Giordano M,Dran GI
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
Enhancement of antitumor immunity by combination of anti-CTLA-4 antibody and radioimmunotherapy through the suppression of Tregs.
Oncology letters
Son CH,Bae J,Lee HR,Yang K,Park YS
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
Immunological effects of vaccines combined with granulocyte colony-stimulating factor on a murine WEHI-3 leukemia model.
Oncology letters
Chen J,Zhang M,Zhou F,Wang J,Niu B,Zhang W
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Proteomic changes of CD4+/CD25+/forkhead box p3+ regulatory T cells in a 30-day rat model of sepsis survival.
Experimental and therapeutic medicine
Jiao Y,Tan S,Xiong J
15-5773 was used in Flow cytometry/Cell sorting to explain the mechanism by which regulatory T-cells (Tregs) naturally recover and indicate that Tregs in the blood and spleen vary.
Fri Dec 01 00:00:00 EST 2017
Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APPSWE/PS1ΔE9 murine model of Alzheimer's disease.
Scientific reports
Minter MR,Hinterleitner R,Meisel M,Zhang C,Leone V,Zhang X,Oyler-Castrillo P,Zhang X,Musch MW,Shen X,Jabri B,Chang EB,Tanzi RE,Sisodia SS
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Sep 05 00:00:00 EDT 2017
Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages.
EBioMedicine
Li Y,Liu X,Duan W,Tian H,Zhu G,He H,Yao S,Yi S,Song W,Tang H
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function.
Scientific reports
Huang J,Wang L,Dahiya S,Beier UH,Han R,Samanta A,Bergman J,Sotomayor EM,Seto E,Kozikowski AP,Hancock WW
15-5773 was used in Flow cytometry/Cell sorting to examine the effects of global histone/protein deacetylase inhibition on regulatory T cell function.
Thu Aug 17 00:00:00 EDT 2017
Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation.
Scientific reports
Zhang H,Qi Y,Yuan Y,Cai L,Xu H,Zhang L,Su B,Nie H
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Feb 06 00:00:00 EST 2017
Rational combination of oncolytic vaccinia virus and PD-L1 blockade works synergistically to enhance therapeutic efficacy.
Nature communications
Liu Z,Ravindranathan R,Kalinski P,Guo ZS,Bartlett DL
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Mar 27 00:00:00 EDT 2017
MSC-derived Extracellular Vesicles Attenuate Immune Responses in Two Autoimmune Murine Models: Type 1 Diabetes and Uveoretinitis.
Stem cell reports
Shigemoto-Kuroda T,Oh JY,Kim DK,Jeong HJ,Park SY,Lee HJ,Park JW,Kim TW,An SY,Prockop DJ,Lee RH
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue May 09 00:00:00 EDT 2017
The effects of freeze-dried Ganoderma lucidum mycelia on a recurrent oral ulceration rat model.
BMC complementary and alternative medicine
Xie L,Zhong X,Liu D,Liu L,Xia Z
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2017
Compensatory upregulation of PD-1, LAG-3, and CTLA-4 limits the efficacy of single-agent checkpoint blockade in metastatic ovarian cancer.
Oncoimmunology
Huang RY,Francois A,McGray AR,Miliotto A,Odunsi K
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Multiple functional therapeutic effects of TnP: A small stable synthetic peptide derived from fish venom in a mouse model of multiple sclerosis.
PloS one
Komegae EN,Souza TA,Grund LZ,Lima C,Lopes-Ferreira M
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu Aug 17 00:00:00 EDT 2017
Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction.
The Journal of biological chemistry
Hayakawa M,Hayakawa H,Petrova T,Ritprajak P,Sutavani RV,Jiménez-Andrade GY,Sano Y,Choo MK,Seavitt J,Venigalla RKC,Otsu K,Georgopoulos K,Arthur JSC,Park JM
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Feb 03 00:00:00 EST 2017
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity.
Nature communications
Zamarin D,Holmgaard RB,Ricca J,Plitt T,Palese P,Sharma P,Merghoub T,Wolchok JD,Allison JP
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Feb 13 00:00:00 EST 2017
Splenic CD4+ T Cells in Progressive Visceral Leishmaniasis Show a Mixed Effector-Regulatory Phenotype and Impair Macrophage Effector Function through Inhibitory Receptor Expression.
PloS one
Medina-Colorado AA,Osorio EY,Saldarriaga OA,Travi BL,Kong F,Spratt H,Soong L,Melby PC
15-5773 was used in Flow cytometry/Cell sorting to show the expression of counter-regulatory molecules on splenic CD4+ T cells and macrophages promotes a permissive macrophage phenotype, attenuating intracellular parasite control.
Mon Aug 07 00:00:00 EDT 2017
Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche.
Cell
Clever D,Roychoudhuri R,Constantinides MG,Askenase MH,Sukumar M,Klebanoff CA,Eil RL,Hickman HD,Yu Z,Pan JH,Palmer DC,Phan AT,Goulding J,Gattinoni L,Goldrath AW,Belkaid Y,Restifo NP
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu Aug 25 00:00:00 EDT 2016
B-cell anergy induces a Th17 shift in a novel B lymphocyte transgenic NOD mouse model, the 116C-NOD mouse.
European journal of immunology
Carrascal J,Carrillo J,Arpa B,Egia-Mendikute L,Rosell-Mases E,Pujol-Autonell I,Planas R,Mora C,Mauricio D,Ampudia RM,Vives-Pi M,Verdaguer J
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Natural genetic variation profoundly regulates gene expression in immune cells and dictates susceptibility to CNS autoimmunity.
Genes and immunity
Bearoff F,Del Rio R,Case LK,Dragon JA,Nguyen-Vu T,Lin CY,Blankenhorn EP,Teuscher C,Krementsov DN
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
Rapamycin ameliorates CCl4-induced liver fibrosis in mice through reciprocal regulation of the Th17/Treg cell balance.
Molecular medicine reports
Gu L,Deng WS,Sun XF,Zhou H,Xu Q
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Genomic and immunologic factors associated with viral pathogenesis in a lethal EV71 infected neonatal mouse model.
Molecular medicine reports
Yue Y,Li P,Song N,Li B,Li Z,Guo Y,Zhang W,Wei MQ,Gai Z,Meng H,Wang J,Qin L
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2016
Age-dependent divergent effects of OX40L treatment on the development of diabetes in NOD mice.
Autoimmunity
Haddad CS,Bhattacharya P,Alharshawi K,Marinelarena A,Kumar P,El-Sayed O,Elshabrawy HA,Epstein AL,Prabhakar BS
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Porcine Treg depletion with a novel diphtheria toxin-based anti-human CCR4 immunotoxin.
Veterinary immunology and immunopathology
Wang Z,Navarro-Alvarez N,Shah JA,Zhang H,Huang Q,Zheng Q,Madsen JC,Sachs DH,Huang CA,Wang Z
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
Kappa opioid receptor activation alleviates experimental autoimmune encephalomyelitis and promotes oligodendrocyte-mediated remyelination.
Nature communications
Du C,Duan Y,Wei W,Cai Y,Chai H,Lv J,Du X,Zhu J,Xie X
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Apr 04 00:00:00 EDT 2016
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
Nature communications
Ruhland MK,Loza AJ,Capietto AH,Luo X,Knolhoff BL,Flanagan KC,Belt BA,Alspach E,Leahy K,Luo J,Schaffer A,Edwards JR,Longmore G,Faccio R,DeNardo DG,Stewart SA
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Wed Jun 08 00:00:00 EDT 2016
Tubular Dickkopf-3 promotes the development of renal atrophy and fibrosis.
JCI insight
Federico G,Meister M,Mathow D,Heine GH,Moldenhauer G,Popovic ZV,Nordström V,Kopp-Schneider A,Hielscher T,Nelson PJ,Schaefer F,Porubsky S,Fliser D,Arnold B,Gröne HJ
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu Jan 21 00:00:00 EST 2016
Vitamin D3 improves the effects of low dose Der p 2 allergoid treatment in Der p 2 sensitized BALB/c mice.
Clinical and molecular allergy : CMA
Petrarca C,Clemente E,Amato V,Gatta A,Cortese S,Lamolinara A,Rossi C,Zanotta S,Mistrello G,Paganelli R,Di Gioacchino M
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Aug 08 00:00:00 EDT 2016
Viral Infection of the Central Nervous System Exacerbates Interleukin-10 Receptor Deficiency-Mediated Colitis in SJL Mice.
PloS one
Uhde AK,Herder V,Akram Khan M,Ciurkiewicz M,Schaudien D,Teich R,Floess S,Baumgärtner W,Huehn J,Beineke A
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Aug 25 00:00:00 EDT 2017
Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy.
Nature communications
Shi LZ,Fu T,Guan B,Chen J,Blando JM,Allison JP,Xiong L,Subudhi SK,Gao J,Sharma P
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Aug 08 00:00:00 EDT 2016
Exploring the induction of preproinsulin-specific Foxp3(+) CD4(+) Treg cells that inhibit CD8(+) T cell-mediated autoimmune diabetes by DNA vaccination.
Scientific reports
Stifter K,Schuster C,Schlosser M,Boehm BO,Schirmbeck R
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Jul 11 00:00:00 EDT 2016
Proteinase 3 on apoptotic cells disrupts immune silencing in autoimmune vasculitis.
The Journal of clinical investigation
Millet A,Martin KR,Bonnefoy F,Saas P,Mocek J,Alkan M,Terrier B,Kerstein A,Tamassia N,Satyanarayanan SK,Ariel A,Ribeil JA,Guillevin L,Cassatella MA,Mueller A,Thieblemont N,Lamprecht P,Mouthon L,Perruche S,Witko-Sarsat V
15-5773 was used in Flow cytometry/Cell sorting to investigate disruption of immune silencing by proteinase 3 on apoptotic cells.
Mon Nov 02 00:00:00 EST 2015
FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3.
The Journal of clinical investigation
Wang L,Liu Y,Han R,Beier UH,Bhatti TR,Akimova T,Greene MI,Hiebert SW,Hancock WW
15-5773 was used in Flow cytometry/Cell sorting to show that histone/protein deacetylase 3 is essential for the normal development and suppressive functions of thymic and peripheral FOXP3+ Tregs.
Mon Mar 02 00:00:00 EST 2015
Towards programming immune tolerance through geometric manipulation of phosphatidylserine.
Biomaterials
Roberts RA,Eitas TK,Byrne JD,Johnson BM,Short PJ,McKinnon KP,Reisdorf S,Luft JC,DeSimone JM,Ting JP
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2015
MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice.
Proceedings of the National Academy of Sciences of the United States of America
Wu L,Li N,Zhang M,Xue SL,Cassady K,Lin Q,Riggs AD,Zeng D
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Dec 29 00:00:00 EST 2015
Intermuscular and perimuscular fat expansion in obesity correlates with skeletal muscle T cell and macrophage infiltration and insulin resistance.
International journal of obesity (2005)
Khan IM,Perrard XY,Brunner G,Lui H,Sparks LM,Smith SR,Wang X,Shi ZZ,Lewis DE,Wu H,Ballantyne CM
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2015
Leptin receptor signaling in T cells is required for Th17 differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Reis BS,Lee K,Fanok MH,Mascaraque C,Amoury M,Cohn LB,Rogoz A,Dallner OS,Moraes-Vieira PM,Domingos AI,Mucida D
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
Effect of Retinoic Acid in a Mouse Model of Allergic Rhinitis.
Allergy, asthma & immunology research
Son HL,Park HR,Park YJ,Kim SW
15-5773 was used in Flow cytometry/Cell sorting to investigate the effects of all-trans retinoic acid in an allergic rhinitis mouse model.
Sun Nov 01 00:00:00 EDT 2015
Deficits in endogenous adenosine formation by ecto-5'-nucleotidase/CD73 impair neuromuscular transmission and immune competence in experimental autoimmune myasthenia gravis.
Mediators of inflammation
Oliveira L,Correia A,Cristina Costa A,Guerra-Gomes S,Ferreirinha F,Magalhães-Cardoso MT,Vilanova M,Correia-de-Sá P
15-5773 was used in Flow cytometry/Cell sorting to investigate the role of ecto-5'-nucleotidase/CD73 in a rat model of experimental autoimmune myasthenia gravis.
Mon Jan 11 00:00:00 EST 2016
Loss of Immunization-Induced Epitope-Specific CD4 T-Cell Response following Anaplasma marginale Infection Requires Presence of the T-Cell Epitope on the Pathogen and Is Not Associated with an Increase in Lymphocytes Expressing Known Regulatory Cell Phenotypes.
Clinical and vaccine immunology : CVI
Brown WC,Turse JE,Lawrence PK,Johnson WC,Scoles GA,Deringer JR,Sutten EL,Han S,Norimine J
15-5773 was used in Flow cytometry/Cell sorting to study the induction of T-cell exhaustion following infection with A. marginale and study the correlation with an increase in CD4(+) CD25(+) Foxp3(+) T cells.
Wed Jul 01 00:00:00 EDT 2015
Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology.
Nature communications
Baruch K,Rosenzweig N,Kertser A,Deczkowska A,Sharif AM,Spinrad A,Tsitsou-Kampeli A,Sarel A,Cahalon L,Schwartz M
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Aug 18 00:00:00 EDT 2015
Vesicular stomatitis virus expressing interferon-β is oncolytic and promotes antitumor immune responses in a syngeneic murine model of non-small cell lung cancer.
Oncotarget
Patel MR,Jacobson BA,Ji Y,Drees J,Tang S,Xiong K,Wang H,Prigge JE,Dash AS,Kratzke AK,Mesev E,Etchison R,Federspiel MJ,Russell SJ,Kratzke RA
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Oct 20 00:00:00 EDT 2015
Promotion of regulatory T cell induction by immunomodulatory herbal medicine licorice and its two constituents.
Scientific reports
Guo A,He D,Xu HB,Geng CA,Zhao J
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Sep 15 00:00:00 EDT 2015
Antibiotics in neonatal life increase murine susceptibility to experimental psoriasis.
Nature communications
Zanvit P,Konkel JE,Jiao X,Kasagi S,Zhang D,Wu R,Chia C,Ajami NJ,Smith DP,Petrosino JF,Abbatiello B,Nakatsukasa H,Chen Q,Belkaid Y,Chen ZJ,Chen W
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2015
MicroRNA-146a regulates ICOS-ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres.
Nature communications
Pratama A,Srivastava M,Williams NJ,Papa I,Lee SK,Dinh XT,Hutloff A,Jordan MA,Zhao JL,Casellas R,Athanasopoulos V,Vinuesa CG
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Mar 06 00:00:00 EST 2015
Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression.
Cancer cell
Xu C,Fillmore CM,Koyama S,Wu H,Zhao Y,Chen Z,Herter-Sprie GS,Akbay EA,Tchaicha JH,Altabef A,Reibel JB,Walton Z,Ji H,Watanabe H,Jänne PA,Castrillon DH,Rustgi AK,Bass AJ,Freeman GJ,Padera RF,Dranoff G,Hammerman PS,Kim CF,Wong KK
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon May 12 00:00:00 EDT 2014
The adaptor TRAF5 limits the differentiation of inflammatory CD4(+) T cells by antagonizing signaling via the receptor for IL-6.
Nature immunology
Nagashima H,Okuyama Y,Asao A,Kawabe T,Yamaki S,Nakano H,Croft M,Ishii N,So T
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu May 01 00:00:00 EDT 2014
Foxp3+ CD4+ T cells improve healing after myocardial infarction by modulating monocyte/macrophage differentiation.
Circulation research
Weirather J,Hofmann UD,Beyersdorf N,Ramos GC,Vogel B,Frey A,Ertl G,Kerkau T,Frantz S
15-5773 was used in Flow cytometry/Cell sorting to determine the mechanisms by which regulatory T cells promote an appropriate healing response after a heart attack.
Fri Jun 20 00:00:00 EDT 2014
Ultraviolet B light attenuates the systemic immune response in central nervous system autoimmunity.
Annals of neurology
Breuer J,Schwab N,Schneider-Hohendorf T,Marziniak M,Mohan H,Bhatia U,Gross CC,Clausen BE,Weishaupt C,Luger TA,Meuth SG,Loser K,Wiendl H
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu May 01 00:00:00 EDT 2014
Tryptophan catabolism restricts IFN-γ-expressing neutrophils and Clostridium difficile immunopathology.
Journal of immunology (Baltimore, Md. : 1950)
El-Zaatari M,Chang YM,Zhang M,Franz M,Shreiner A,McDermott AJ,van der Sluijs KF,Lutter R,Grasberger H,Kamada N,Young VB,Huffnagle GB,Kao JY
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Jul 15 00:00:00 EDT 2014
Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge.
Human vaccines & immunotherapeutics
Wang S,Wu B,Xue J,Wang M,Chen R,Wang B
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Jan 05 00:00:00 EST 2015
High-dose interferon-γ promotes abortion in mice by suppressing Treg and Th17 polarization.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Liu HY,Liu ZK,Chao H,Li Z,Song Z,Yang Y,Peng JP
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu May 01 00:00:00 EDT 2014
Direct detection of FoxP3 expression in thymic double-negative CD4-CD8- cells by flow cytometry.
Scientific reports
Liu G,Li Z,Wei Y,Lin Y,Yang C,Liu T
15-5773 was used in Flow cytometry/Cell sorting to suggest that Foxp3 expression in double-negative CD4+CD8+ T-cell precursors can directly be detected by flow cytometry.
Fri Jul 25 00:00:00 EDT 2014
Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4⁺ T cell immunity.
Nature immunology
Reis BS,Rogoz A,Costa-Pinto FA,Taniuchi I,Mucida D
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
Genetic deletion of chemokine receptor Ccr7 exacerbates atherogenesis in ApoE-deficient mice.
Cardiovascular research
Wan W,Lionakis MS,Liu Q,Roffê E,Murphy PM
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
Double deficiency in IL-17 and IFN-γ signalling significantly suppresses the development of diabetes in the NOD mouse.
Diabetologia
Kuriya G,Uchida T,Akazawa S,Kobayashi M,Nakamura K,Satoh T,Horie I,Kawasaki E,Yamasaki H,Yu L,Iwakura Y,Sasaki H,Nagayama Y,Kawakami A,Abiru N
15-5773 was used in Flow cytometry/Cell sorting to study the suppression of diabetes in NOD mice due to IL-17 and IFN-γ deficiency.
Thu Aug 01 00:00:00 EDT 2013
Mycophenolic acid derivative 118 improves outcome of skin grafts by suppressing IL-17 production.
Acta pharmacologica Sinica
Kong FY,Chen W,He SJ,Lin ZM,Li X,Zhang XH,Yang XQ,Zhu FH,Tong XK,Zhou Y,Tang W,Duan WH,Zuo JP
15-5773 was used in Flow cytometry/Cell sorting to investigate the interaction between the mycophenolic acid derivative, 118, and the immune environment in a murine allogeneic skin graft model.
Mon Jul 01 00:00:00 EDT 2013
PLG scaffold delivered antigen-specific regulatory T cells induce systemic tolerance in autoimmune diabetes.
Tissue engineering. Part A
Graham JG,Zhang X,Goodman A,Pothoven K,Houlihan J,Wang S,Gower RM,Luo X,Shea LD
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Sat Jun 01 00:00:00 EDT 2013
Nod2 activates NF-kB in CD4+ T cells but its expression is dispensable for T cell-induced colitis.
PloS one
Zanello G,Goethel A,Forster K,Geddes K,Philpott DJ,Croitoru K
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Thu Jul 31 00:00:00 EDT 2014
Regulatory T cells are protective in systemic inflammation response syndrome induced by zymosan in mice.
PloS one
Jia W,Cao L,Yang S,Dong H,Zhang Y,Wei H,Jing W,Hou L,Wang C
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Dec 17 00:00:00 EST 2013
Artemisinin analogue SM934 ameliorates murine experimental autoimmune encephalomyelitis through enhancing the expansion and functions of regulatory T cell.
PloS one
Li X,Li TT,Zhang XH,Hou LF,Yang XQ,Zhu FH,Tang W,Zuo JP
15-5773 was used in Flow cytometry/Cell sorting to explore the effects of SM934 on Th1, Th17 and Treg cell differentiation.
Wed Apr 16 00:00:00 EDT 2014
Activation of CD4+ T lymphocytes improves wound healing and survival after experimental myocardial infarction in mice.
Circulation
Hofmann U,Beyersdorf N,Weirather J,Podolskaya A,Bauersachs J,Ertl G,Kerkau T,Frantz S
15-5773 was used in Flow cytometry/Cell sorting to investigate the role of CD4+ T lymphocytes in wound healing after experimental myocardial infarction in mice.
Tue Apr 03 00:00:00 EDT 2012
Gene therapy-mediated reprogramming tumor infiltrating T cells using IL-2 and inhibiting NF-κB signaling improves the efficacy of immunotherapy in a brain cancer model.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Mineharu Y,Muhammad AK,Yagiz K,Candolfi M,Kroeger KM,Xiong W,Puntel M,Liu C,Levy E,Lugo C,Kocharian A,Allison JP,Curran MA,Lowenstein PR,Castro MG
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2012
Role of donor-specific regulatory T cells in long-term acceptance of rat hind limb allograft.
PloS one
Wang Y,Zheng Z,Wang Y,Liu J,Li N,Hu X,Han F,Liu Y,Hu D
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Feb 19 00:00:00 EST 2013
Pharyngeal microflora disruption by antibiotics promotes airway hyperresponsiveness after respiratory syncytial virus infection.
PloS one
Ni K,Li S,Xia Q,Zang N,Deng Y,Xie X,Luo Z,Luo Y,Wang L,Fu Z,Liu E
15-5773 was used in Flow cytometry/Cell sorting to demonstrate that antibiotic treatment clears pharyngeal commensal bacteria and depletes levels of pulmonary Tregs.
Wed Nov 28 00:00:00 EST 2012
CD4(+) CD25(+) FoxP3(+) regulatory T cells suppress cytotoxicity of CD8(+) effector T cells: implications for their capacity to limit inflammatory central nervous system damage at the parenchymal level.
Journal of neuroinflammation
Göbel K,Bittner S,Melzer N,Pankratz S,Dreykluft A,Schuhmann MK,Meuth SG,Wiendl H
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Feb 28 00:00:00 EST 2012
Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2.
The American journal of pathology
Yamamoto Y,Otani S,Hirai H,Nagata K,Aritake K,Urade Y,Narumiya S,Yokozeki H,Nakamura M,Satoh T
15-5773 was used in Flow cytometry/Cell sorting to demonstrate that prostaglandin D2 signals through CRTH2 and DP to mediate contact hypersensitivity.
Fri Jul 01 00:00:00 EDT 2011
MHC class I family proteins retard systemic lupus erythematosus autoimmunity and B cell lymphomagenesis.
Journal of immunology (Baltimore, Md. : 1950)
McPhee CG,Sproule TJ,Shin DM,Bubier JA,Schott WH,Steinbuck MP,Avenesyan L,Morse HC,Roopenian DC
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2011
Restricted microbiota and absence of cognate TCR antigen leads to an unbalanced generation of Th17 cells.
Journal of immunology (Baltimore, Md. : 1950)
Lochner M,Bérard M,Sawa S,Hauer S,Gaboriau-Routhiau V,Fernandez TD,Snel J,Bousso P,Cerf-Bensussan N,Eberl G
15-5773 was used in Flow cytometry/Cell sorting to demonstrate that a complex microbiota and cognate antigen are required to generate a properly regulated set of Foxp3+RORγt+ T cells and Th17 cells.
Tue Feb 01 00:00:00 EST 2011
CXCR3 deficiency exacerbates liver disease and abrogates tolerance in a mouse model of immune-mediated hepatitis.
Journal of immunology (Baltimore, Md. : 1950)
Erhardt A,Wegscheid C,Claass B,Carambia A,Herkel J,Mittrücker HW,Panzer U,Tiegs G
15-5773 was used in Flow cytometry/Cell sorting to discovered that CXCR3(+)T-bet(+)IL-10(+) Tregs are generated in the liver, disseminate into the organism and migrate into the liver, limiting immune-mediated liver damage.
Sun May 01 00:00:00 EDT 2011
In vivo administration of hypomethylating agents mitigate graft-versus-host disease without sacrificing graft-versus-leukemia.
Blood
Choi J,Ritchey J,Prior JL,Holt M,Shannon WD,Deych E,Piwnica-Worms DR,DiPersio JF
15-5773 was used in Flow cytometry/Cell sorting to demonstrate that hypomethylating agents, decitabine and azacitidine, induce FOXP3 expression in CD4(+)CD25(-) T cells both in vitro and in vivo.
Thu Jul 08 00:00:00 EDT 2010
CCR6 marks regulatory T cells as a colon-tropic, IL-10-producing phenotype.
Journal of immunology (Baltimore, Md. : 1950)
Kitamura K,Farber JM,Kelsall BL
15-5773 was used in Flow cytometry/Cell sorting to conclude that CCR6 expression on Treg cells was required for the full function of Treg cell-mediated suppression in a model of colitis.
Wed Sep 15 00:00:00 EDT 2010
Development of a nanoparticulate formulation of retinoic acid that suppresses Th17 cells and upregulates regulatory T cells.
Self/nonself
Capurso NA,Look M,Jeanbart L,Nowyhed H,Abraham C,Craft J,Fahmy TM
Published figure using FOXP3 monoclonal antibody (Product # 15-5773-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2010
Naturally-existing CD4(+)CD25(+)Foxp3(+) regulatory T cells are required for tolerance to experimental autoimmune thyroiditis induced by either exogenous or endogenous autoantigen.
Journal of autoimmunity
Morris GP,Brown NK,Kong YC
15-5773 was used in Flow cytometry/Cell sorting to highlight the important role of Tregs in mediating self-tolerance in relation to experimental autoimmune thyroiditis.
Sat Aug 01 00:00:00 EDT 2009
In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells.
The Journal of experimental medicine
Lochner M,Peduto L,Cherrier M,Sawa S,Langa F,Varona R,Riethmacher D,Si-Tahar M,Di Santo JP,Eberl G
15-5773 was used in Flow cytometry/Cell sorting to study how potentially antagonistic pro-inflammatory IL-17-producing and regulatory Foxp3(+) RORgamma t(+) T cells coexist and are tightly controlled.
Mon Jun 09 00:00:00 EDT 2008
