Product References
TGFβ1+CCR5+ neutrophil subset increases in bone marrow and causes age-related osteoporosis in male mice.
Nature communications
Li J,Yao Z,Liu X,Duan R,Yi X,Ayoub A,Sanders JO,Mesfin A,Xing L,Boyce BF
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Wed Jan 11 00:00:00 EST 2023
Macrophagic AMPKα1 orchestrates regenerative inflammation induced by glucocorticoids.
EMBO reports
Caratti G,Desgeorges T,Juban G,Stifel U,Fessard A,Koenen M,Caratti B,Théret M,Skurk C,Chazaud B,Tuckermann JP,Mounier R
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Mon Feb 06 00:00:00 EST 2023
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
The NKCC1 ion transporter modulates microglial phenotype and inflammatory response to brain injury in a cell-autonomous manner.
PLoS biology
Tóth K,Lénárt N,Berki P,Fekete R,Szabadits E,Pósfai B,Cserép C,Alatshan A,Benkő S,Kiss D,Hübner CA,Gulyás A,Kaila K,Környei Z,Dénes Á
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2022
Gene-dosage effect of Pfkfb3 on monocyte/macrophage biology in atherosclerosis.
British journal of pharmacology
Guo S,Li A,Fu X,Li Z,Cao K,Song M,Huang S,Li Z,Yan J,Wang L,Dai X,Feng D,Wang Y,He J,Huo Y,Xu Y
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2022
Mineralocorticoid receptor antagonists and glucocorticoids differentially affect skeletal muscle inflammation and pathology in muscular dystrophy.
JCI insight
Howard ZM,Gomatam CK,Rabolli CP,Lowe J,Piepho AB,Bansal SS,Accornero F,Rafael-Fortney JA
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Mon Oct 10 00:00:00 EDT 2022
Therapeutic CFTR Correction Normalizes Systemic and Lung-Specific S1P Level Alterations Associated with Heart Failure.
International journal of molecular sciences
Uhl FE,Vanherle L,Matthes F,Meissner A
25-5932-82 was used in Flow cytometry/Cell sorting to suggest an important role for the CFTR-S1P axis in HF-mediated systemic and pulmonary inflammation.
Fri Jan 14 00:00:00 EST 2022
TNF hampers intestinal tissue repair in colitis by restricting IL-22 bioavailability.
Mucosal immunology
Ninnemann J,Winsauer C,Bondareva M,Kühl AA,Lozza L,Durek P,Lissner D,Siegmund B,Kaufmann SHE,Mashreghi MF,Nedospasov SA,Kruglov AA
25-5932-82 was used in Flow cytometry/Cell sorting to show how anti-TNF therapy induces mucosal healing by increasing IL-22 availability and implicates new therapeutic opportunities for IBD.
Fri Apr 01 00:00:00 EDT 2022
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Pancreatic Cancer Chemotherapy Is Potentiated by Induction of Tertiary Lymphoid Structures in Mice.
Cellular and molecular gastroenterology and hepatology
Delvecchio FR,Fincham REA,Spear S,Clear A,Roy-Luzarraga M,Balkwill FR,Gribben JG,Bombardieri M,Hodivala-Dilke K,Capasso M,Kocher HM
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Mon Mar 28 00:00:00 EDT 2022
Disrupted Iron Metabolism and Mortality during Co-infection with Malaria and an Intestinal Gram-Negative Extracellular Pathogen.
Cell reports
Dos Santos LI,Torres TA,Diniz SQ,Gonçalves R,Caballero-Flores G,Núñez G,Gazzinelli RT,Maloy KJ,Ribeiro do V Antonelli L
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Myeloid DJ-1 deficiency protects acetaminophen-induced acute liver injury through decreasing inflammatory response.
Aging
Wang B,Li J,Jiao J,Xu M,Luo Y,Wang F,Xia Q,Gao Y,Feng Y,Kong X,Sun X
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Wed Jul 21 00:00:00 EDT 2021
NOX4 regulates macrophage apoptosis resistance to induce fibrotic progression.
The Journal of biological chemistry
Larson-Casey JL,Gu L,Kang J,Dhyani A,Carter AB
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Thu Jul 01 00:00:00 EDT 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
Abraxane-induced bone marrow CD11b+ myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with 64Cu-labeled anti-CD11b and prevented by anti-CSF-1.
Theranostics
Cao Q,Huang Q,Wang YA,Li C
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Fri Jul 23 00:00:00 EDT 2021
Inflammatory resolution and vascular barrier restoration after retinal ischemia reperfusion injury.
Journal of neuroinflammation
Abcouwer SF,Shanmugam S,Muthusamy A,Lin CM,Kong D,Hager H,Liu X,Antonetti DA
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Thu Aug 26 00:00:00 EDT 2021
Roles of lung-recruited monocytes and pulmonary Vascular Endothelial Growth Factor (VEGF) in resolving Ventilator-Induced Lung Injury (VILI).
PloS one
Lin CK,Huang TH,Yang CT,Shi CS
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
DA-DRD5 signaling controls colitis by regulating colonic M1/M2 macrophage polarization.
Cell death & disease
Liu L,Wu Y,Wang B,Jiang Y,Lin L,Li X,Yang S
25-5932 was used in Flow cytometry/Cell sorting to provide demonstration of DA-DRD5 signaling in colonic macrophages controlling the development of colitis by regulating M1/M2 macrophage polarization.
Mon May 17 00:00:00 EDT 2021
Intestinal barrier dysfunction plays an integral role in arthritis pathology and can be targeted to ameliorate disease.
Med (New York, N.Y.)
Matei DE,Menon M,Alber DG,Smith AM,Nedjat-Shokouhi B,Fasano A,Magill L,Duhlin A,Bitoun S,Gleizes A,Hacein-Bey-Abina S,Manson JJ,Rosser EC,Klein N,Blair PA,Mauri C
25-5932-82 was used in Flow Cytometry to analyze changes in markers of gut permeability, damage, and inflammation in peripheral blood and serum of rheumatoid arthritis patients, as well as relevant organs in engineered arthritic mice.
Fri Jul 09 00:00:00 EDT 2021
Plaque-associated myeloid cells derive from resident microglia in an Alzheimer's disease model.
The Journal of experimental medicine
Reed-Geaghan EG,Croxford AL,Becher B,Landreth GE
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Mon Apr 06 00:00:00 EDT 2020
Proenkephalin+ regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function.
Proceedings of the National Academy of Sciences of the United States of America
Shime H,Odanaka M,Tsuiji M,Matoba T,Imai M,Yasumizu Y,Uraki R,Minohara K,Watanabe M,Bonito AJ,Fukuyama H,Ohkura N,Sakaguchi S,Morita A,Yamazaki S
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Tue Aug 25 00:00:00 EDT 2020
IgE Contributes to Atherosclerosis and Obesity by Affecting Macrophage Polarization, Macrophage Protein Network, and Foam Cell Formation.
Arteriosclerosis, thrombosis, and vascular biology
Zhang X,Li J,Luo S,Wang M,Huang Q,Deng Z,de Febbo C,Daoui A,Liew PX,Sukhova GK,Metso J,Jauhiainen M,Shi GP,Guo J
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2020
Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.
British journal of pharmacology
De Cicco P,Ercolano G,Rubino V,Terrazzano G,Ruggiero G,Cirino G,Ianaro A
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
Temporospatial distribution and transcriptional profile of retinal microglia in the oxygen-induced retinopathy mouse model.
Glia
Boeck M,Thien A,Wolf J,Hagemeyer N,Laich Y,Yusuf D,Backofen R,Zhang P,Boneva S,Stahl A,Hilgendorf I,Agostini H,Prinz M,Wieghofer P,Schlunck G,Schlecht A,Lange C
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2020
Astrocytes promote a protective immune response to brain Toxoplasma gondii infection via IL-33-ST2 signaling.
PLoS pathogens
Still KM,Batista SJ,O'Brien CA,Oyesola OO,Früh SP,Webb LM,Smirnov I,Kovacs MA,Cowan MN,Hayes NW,Thompson JA,Tait Wojno ED,Harris TH
25-5932 was used in Flow cytometry/Cell sorting to show that IL-33 is expressed by oligodendrocytes and astrocytes during T. gondii infection, is released locally into the cerebrospinal fluid of T. gondii-infected animals, and is required for control of infection.
Thu Oct 01 00:00:00 EDT 2020
Characterization and regulation of osteoclast precursors following chronic Porphyromonas gingivalis infection.
Journal of leukocyte biology
Zhao Y,Li Z,Su L,Ballesteros-Tato A,Katz J,Michalek SM,Feng X,Zhang P
25-5932-82 was used in Flow Cytometry to provide new insights into the characterization and regulation of OCP following a chronic bacterial infection.
Thu Oct 01 00:00:00 EDT 2020
Characterization and regulation of osteoclast precursors following chronic Porphyromonas gingivalis infection.
Journal of leukocyte biology
Zhao Y,Li Z,Su L,Ballesteros-Tato A,Katz J,Michalek SM,Feng X,Zhang P
25-5932-82 was used in Flow Cytometry to provide new insights into the characterization and regulation of OCP following a chronic bacterial infection.
Thu Oct 01 00:00:00 EDT 2020
Antitumor Effect and Immune Response of Nanosecond Pulsed Electric Fields in Pancreatic Cancer.
Frontiers in oncology
Zhao J,Chen S,Zhu L,Zhang L,Liu J,Xu D,Tian G,Jiang T
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Fri Oct 28 00:00:00 EDT 2022
Methylprednisolone alleviates multiple sclerosis by expanding myeloid-derived suppressor cells via glucocorticoid receptor β and S100A8/9 up-regulation.
Journal of cellular and molecular medicine
Wang Z,Zheng G,Li G,Wang M,Ma Z,Li H,Wang XY,Yi H
25-5932 was used in Flow cytometry/Cell sorting to suggest that GCs treatment may help relieve the acute phase of MS by expanding MDSC through up-regulating of GR signalling and S100A8/A9 heterodimers.
Tue Dec 01 00:00:00 EST 2020
Effects of Hypertonic Saline and Hydroxyethyl Starch on Myeloid-Derived Suppressor Cells in Hemorrhagic Shock Mice under Secondary Bacterial Attack.
BioMed research international
Jiang JK,Hong LJ,Lu YQ
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
Site-1 protease ablation in the osterix-lineage in mice results in bone marrow neutrophilia and hematopoietic stem cell alterations.
Biology open
Patra D,Kim J,Zhang Q,Tycksen E,Sandell LJ
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Tue Jun 23 00:00:00 EDT 2020
The impact of Clonorchis sinensis infection on immune response in mice with type II collagen-induced arthritis.
BMC immunology
Li X,Yang Y,Qin S,Kong F,Yan C,Cheng W,Pan W,Yu Q,Hua H,Zheng K,Tang R
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Mon Feb 17 00:00:00 EST 2020
The impact of Clonorchis sinensis infection on immune response in mice with type II collagen-induced arthritis.
BMC immunology
Li X,Yang Y,Qin S,Kong F,Yan C,Cheng W,Pan W,Yu Q,Hua H,Zheng K,Tang R
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Mon Feb 17 00:00:00 EST 2020
GDF3 Protects Mice against Sepsis-Induced Cardiac Dysfunction and Mortality by Suppression of Macrophage Pro-Inflammatory Phenotype.
Cells
Wang L,Li Y,Wang X,Wang P,Essandoh K,Cui S,Huang W,Mu X,Liu Z,Wang Y,Peng T,Fan GC
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Fri Jan 03 00:00:00 EST 2020
The Transcription Factor Nfix Requires RhoA-ROCK1 Dependent Phagocytosis to Mediate Macrophage Skewing during Skeletal Muscle Regeneration.
Cells
Saclier M,Lapi M,Bonfanti C,Rossi G,Antonini S,Messina G
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Fri Mar 13 00:00:00 EDT 2020
Extracellular miR-146a-5p Induces Cardiac Innate Immune Response and Cardiomyocyte Dysfunction.
ImmunoHorizons
Shimada BK,Yang Y,Zhu J,Wang S,Suen A,Kronstadt SM,Jeyaram A,Jay SM,Zou L,Chao W
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Mon Sep 21 00:00:00 EDT 2020
Extracellular miR-146a-5p Induces Cardiac Innate Immune Response and Cardiomyocyte Dysfunction.
ImmunoHorizons
Shimada BK,Yang Y,Zhu J,Wang S,Suen A,Kronstadt SM,Jeyaram A,Jay SM,Zou L,Chao W
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Mon Sep 21 00:00:00 EDT 2020
Gasdermin D in macrophages restrains colitis by controlling cGAS-mediated inflammation.
Science advances
Ma C,Yang D,Wang B,Wu C,Wu Y,Li S,Liu X,Lassen K,Dai L,Yang S
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Gasdermin D in macrophages restrains colitis by controlling cGAS-mediated inflammation.
Science advances
Ma C,Yang D,Wang B,Wu C,Wu Y,Li S,Liu X,Lassen K,Dai L,Yang S
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Resident macrophages acquire innate immune memory in staphylococcal skin infection.
eLife
Feuerstein R,Forde AJ,Lohrmann F,Kolter J,Ramirez NJ,Zimmermann J,Gomez de Agüero M,Henneke P
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Wed Jul 08 00:00:00 EDT 2020
Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway.
eLife
Kim EH,Woodruff MC,Grigoryan L,Maier B,Lee SH,Mandal P,Cortese M,Natrajan MS,Ravindran R,Ma H,Merad M,Gitlin AD,Mocarski ES,Jacob J,Pulendran B
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Tue Jun 09 00:00:00 EDT 2020
Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis.
Nature communications
Sidwell T,Liao Y,Garnham AL,Vasanthakumar A,Gloury R,Blume J,Teh PP,Chisanga D,Thelemann C,de Labastida Rivera F,Engwerda CR,Corcoran L,Kometani K,Kurosaki T,Smyth GK,Shi W,Kallies A
25-5932 was used in Flow cytometry/Cell sorting to show homeostasis of thymically-derived and peripherally-derived Treg cells is maintained through the balancing of TCR signaling induced transcriptional activity by Bach2.
Tue Jan 14 00:00:00 EST 2020
Host deficiency in ephrin-A1 inhibits breast cancer metastasis.
F1000Research
Shiuan E,Inala A,Wang S,Song W,Youngblood V,Chen J,Brantley-Sieders DM
25-5932 was used in Flow cytometry/Cell sorting to study how ephrin-A1 host deficiency affects cancer growth and metastasis in a murine model of breast cancer.
Mon Feb 01 00:00:00 EST 2021
Host Cathelicidin Exacerbates Group B Streptococcus Urinary Tract Infection.
mSphere
Patras KA,Coady A,Babu P,Shing SR,Ha AD,Rooholfada E,Brandt SL,Geriak M,Gallo RL,Nizet V
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Wed Apr 22 00:00:00 EDT 2020
Host Cathelicidin Exacerbates Group B Streptococcus Urinary Tract Infection.
mSphere
Patras KA,Coady A,Babu P,Shing SR,Ha AD,Rooholfada E,Brandt SL,Geriak M,Gallo RL,Nizet V
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Wed Apr 22 00:00:00 EDT 2020
Regulatory T Cells Support Breast Cancer Progression by Opposing IFN-γ-Dependent Functional Reprogramming of Myeloid Cells.
Cell reports
Clark NM,Martinez LM,Murdock S,deLigio JT,Olex AL,Effi C,Dozmorov MG,Bos PD
25-5932 was used in Flow cytometry/Cell sorting to highlight the strong myeloid dependency of breast cancer and provide the basis for the development of therapeutic strategies based on manipulation of the IFN-γ signaling pathway in monocytes.
Tue Dec 08 00:00:00 EST 2020
Increased flux through the mevalonate pathway mediates fibrotic repair without injury.
The Journal of clinical investigation
Larson-Casey JL,Vaid M,Gu L,He C,Cai GQ,Ding Q,Davis D,Berryhill TF,Wilson LS,Barnes S,Neighbors JD,Hohl RJ,Zimmerman KA,Yoder BK,Longhini ALF,Hanumanthu VS,Surolia R,Antony VB,Carter AB
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2019
ABRO1 promotes NLRP3 inflammasome activation through regulation of NLRP3 deubiquitination.
The EMBO journal
Ren G,Zhang X,Xiao Y,Zhang W,Wang Y,Ma W,Wang X,Song P,Lai L,Chen H,Zhan Y,Zhang J,Yu M,Ge C,Li C,Yin R,Yang X
25-5932 was used in Flow cytometry/Cell sorting to study an ABRO1-mediated regulatory signaling system that controls activation of the NLRP3 inflammasome.
Fri Mar 15 00:00:00 EDT 2019
TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2.
Journal of immunology (Baltimore, Md. : 1950)
Kotov DI,Mitchell JS,Pengo T,Ruedl C,Way SS,Langlois RA,Fife BT,Jenkins MK
25-5932-82 was used in Flow Cytometry to study TCR affinity and influence on regulation of genes in naive T cells that control the differentiation process in cells.
Wed May 01 00:00:00 EDT 2019
The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis.
Cell reports
Hou X,Chen G,Bracamonte-Baran W,Choi HS,Diny NL,Sung J,Hughes D,Won T,Wood MK,Talor MV,Hackam DJ,Klingel K,Davogustto G,Taegtmeyer H,Coppens I,Barin JG,Čiháková D
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Tue Jul 02 00:00:00 EDT 2019
Regulatory T Cells Control the Switch From in situ to Invasive Breast Cancer.
Frontiers in immunology
Martinez LM,Robila V,Clark NM,Du W,Idowu MO,Rutkowski MR,Bos PD
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2020
Regulatory T Cells Control the Switch From in situ to Invasive Breast Cancer.
Frontiers in immunology
Martinez LM,Robila V,Clark NM,Du W,Idowu MO,Rutkowski MR,Bos PD
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2020
Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner.
Cell
Thion MS,Low D,Silvin A,Chen J,Grisel P,Schulte-Schrepping J,Blecher R,Ulas T,Squarzoni P,Hoeffel G,Coulpier F,Siopi E,David FS,Scholz C,Shihui F,Lum J,Amoyo AA,Larbi A,Poidinger M,Buttgereit A,Lledo PM,Greter M,Chan JKY,Amit I,Beyer M,Schultze JL,Schlitzer A,Pettersson S,Ginhoux F,Garel S
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
Advanced Glycation End Products Enhance Murine Monocyte Proliferation in Bone Marrow and Prime Them into an Inflammatory Phenotype through MAPK Signaling.
Journal of diabetes research
Jin X,Liu L,Zhang Y,Xiang Y,Yin G,Lu Y,Shi L,Dong J,Shen C
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Wed Oct 10 00:00:00 EDT 2018
iRhom2-mediated proinflammatory signalling regulates heart repair following myocardial infarction.
JCI insight
Barnette DN,Cahill TJ,Gunadasa-Rohling M,Carr CA,Freeman M,Riley PR
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Thu Feb 08 00:00:00 EST 2018
Differentiated macrophages acquire a pro-inflammatory and cell death-resistant phenotype due to increasing XIAP and p38-mediated inhibition of RipK1.
The Journal of biological chemistry
Rijal D,Ariana A,Wight A,Kim K,Alturki NA,Aamir Z,Ametepe ES,Korneluk RG,Tiedje C,Menon MB,Gaestel M,McComb S,Sad S
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Fri Jul 27 00:00:00 EDT 2018
The Combined Use of Melatonin and an Indoleamine 2,3-Dioxygenase-1 Inhibitor Enhances Vaccine-Induced Protective Cellular Immunity to HPV16-Associated Tumors.
Frontiers in immunology
Moreno ACR,Porchia BFMM,Pagni RL,Souza PDC,Pegoraro R,Rodrigues KB,Barros TB,Aps LRMM,de Araújo EF,Calich VLG,Ferreira LCS
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Thu Sep 19 00:00:00 EDT 2019
Eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challenge.
Nature communications
Yi S,Zhai J,Niu R,Zhu G,Wang M,Liu J,Huang H,Wang Y,Jing X,Kang L,Song W,Shi Y,Tang H
25-5932 was used in Flow cytometry/Cell sorting to suggest that different lung antigen-presenting cells modulate lung cDC1-mediated eosinophil recruitment dynamically.
Mon Sep 24 00:00:00 EDT 2018
Lack of FcRn Impairs Natural Killer Cell Development and Functions in the Tumor Microenvironment.
Frontiers in immunology
Castaneda DC,Dhommée C,Baranek T,Dalloneau E,Lajoie L,Valayer A,Arnoult C,Demattéi MV,Fouquenet D,Parent C,Heuzé-Vourc'h N,Gouilleux-Gruart V
25-5932 was used in Flow cytometry/Cell sorting to elucidate the consequences of neonatal Fc receptor down-regulation in the anti-tumour immune response.
Mon Oct 21 00:00:00 EDT 2019
CCR2+ Monocyte-Derived Infiltrating Macrophages Are Required for Adverse Cardiac Remodeling During Pressure Overload.
JACC. Basic to translational science
Patel B,Bansal SS,Ismahil MA,Hamid T,Rokosh G,Mack M,Prabhu SD
Sun Apr 01 00:00:00 EDT 2018
Helminth-induced IL-4 expands bystander memory CD8+ T cells for early control of viral infection.
Nature communications
Rolot M,Dougall AM,Chetty A,Javaux J,Chen T,Xiao X,Machiels B,Selkirk ME,Maizels RM,Hokke C,Denis O,Brombacher F,Vanderplasschen A,Gillet L,Horsnell WGC,Dewals BG
25-5932 was used in Flow cytometry/Cell sorting to study whether helminth-induced type 2 immunity functionally affects the T virtual memory cell compartment.
Tue Oct 30 00:00:00 EDT 2018
Non-redundant Functions of IL-6 Produced by Macrophages and Dendritic Cells in Allergic Airway Inflammation.
Frontiers in immunology
Gubernatorova EO,Gorshkova EA,Namakanova OA,Zvartsev RV,Hidalgo J,Drutskaya MS,Tumanov AV,Nedospasov SA
25-5932 was used in Flow cytometry/Cell sorting to indicate that IL-6 plays a pathogenic role in the HDM-induced asthma model and that lung macrophages and dendritic cells are the predominant sources of pathogenic IL-6 but contribute differently to the disease.
Wed Oct 02 00:00:00 EDT 2019
Mir-223 regulates the number and function of myeloid-derived suppressor cells in multiple sclerosis and experimental autoimmune encephalomyelitis.
Acta neuropathologica
Cantoni C,Cignarella F,Ghezzi L,Mikesell B,Bollman B,Berrien-Elliott MM,Ireland AR,Fehniger TA,Wu GF,Piccio L
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
CCR2- and CCR2+ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion.
Mucosal immunology
Liu J,Xue Y,Dong D,Xiao C,Lin C,Wang H,Song F,Fu T,Wang Z,Chen J,Pan H,Li Y,Cai D,Li Z
25-5932 was used in Flow cytometry/Cell sorting to show how CCR2(-) and CCR2(+) corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion.
Fri Sep 01 00:00:00 EDT 2017
Infiltrating Myeloid Cells Exert Protumorigenic Actions via Neutrophil Elastase.
Molecular cancer research : MCR
Lerman I,Garcia-Hernandez ML,Rangel-Moreno J,Chiriboga L,Pan C,Nastiuk KL,Krolewski JJ,Sen A,Hammes SR
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2017
Cardiac inflammation in genetic dilated cardiomyopathy caused by MYBPC3 mutation.
Journal of molecular and cellular cardiology
Lynch TL,Ismahil MA,Jegga AG,Zilliox MJ,Troidl C,Prabhu SD,Sadayappan S
25-5932 was used in Flow cytometry/Cell sorting to show that a robust proinflammatory response occurs in the hearts of mice with dilated cardiomyopathy caused by a mutation in the cardiac myosin binding protein-C gene.
Sun Jan 01 00:00:00 EST 2017
Activation of the NLRP3 Inflammasome Is Associated with Valosin-Containing Protein Myopathy.
Inflammation
Nalbandian A,Khan AA,Srivastava R,Llewellyn KJ,Tan B,Shukr N,Fazli Y,Kimonis VE,BenMohamed L
25-5932 was used in Flow cytometry/Cell sorting to investigate whether the NLRP3 inflammasome plays a role in valosin-containing protein-associated diseases, which classically affects the muscles, bones, and brain.
Wed Feb 01 00:00:00 EST 2017
Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression.
Nature communications
Kalkavan H,Sharma P,Kasper S,Helfrich I,Pandyra AA,Gassa A,Virchow I,Flatz L,Brandenburg T,Namineni S,Heikenwalder M,Höchst B,Knolle PA,Wollmann G,von Laer D,Drexler I,Rathbun J,Cannon PM,Scheu S,Bauer J,Chauhan J,Häussinger D,Willimsky G,Löhning M,Schadendorf D,Brandau S,Schuler M,Lang PA,Lang KS
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Mononuclear Phagocytes Are Dispensable for Cardiac Remodeling in Established Pressure-Overload Heart Failure.
PloS one
Patel B,Ismahil MA,Hamid T,Bansal SS,Prabhu SD
25-5932 was used in Flow cytometry/Cell sorting to assess for alterations in MPs.
Thu Aug 10 00:00:00 EDT 2017
BMP Antagonist Gremlin 2 Limits Inflammation After Myocardial Infarction.
Circulation research
Sanders LN,Schoenhard JA,Saleh MA,Mukherjee A,Ryzhov S,McMaster WG,Nolan K,Gumina RJ,Thompson TB,Magnuson MA,Harrison DG,Hatzopoulos AK
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Fri Jul 22 00:00:00 EDT 2016
Alternatively activated macrophages determine repair of the infarcted adult murine heart.
The Journal of clinical investigation
Shiraishi M,Shintani Y,Shintani Y,Ishida H,Saba R,Yamaguchi A,Adachi H,Yashiro K,Suzuki K
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
Tissue damage negatively regulates LPS-induced macrophage necroptosis.
Cell death and differentiation
Li Z,Scott MJ,Fan EK,Li Y,Liu J,Xiao G,Li S,Billiar TR,Wilson MA,Jiang Y,Fan J
25-5932 was used in Flow cytometry/Cell sorting to investigate the mechanism and role of trauma/tissue damage in the regulation of LPS-induced MΦ necroptosis.
Thu Sep 01 00:00:00 EDT 2016
Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.
Immunology
Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Sat Oct 01 00:00:00 EDT 2016
Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model.
Disease models & mechanisms
Chu CJ,Gardner PJ,Copland DA,Liyanage SE,Gonzalez-Cordero A,Kleine Holthaus SM,Luhmann UF,Smith AJ,Ali RR,Dick AD
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
25-5932 was used in Flow cytometry/Cell sorting to suggest persistent viral lytic gene expression during latency causes chronic inflammatory response inducing exhaustion of resident T cells in the ependyma.
Mon Aug 15 00:00:00 EDT 2016
Trypanosoma cruzi Causes Paralyzing Systemic Necrotizing Vasculitis Driven by Pathogen-Specific Type I Immunity in Mice.
Infection and immunity
Roffê E,Marino APMP,Weaver J,Wan W,de Araújo FF,Hoffman V,Santiago HC,Murphy PM
25-5932 was used in Flow cytometry/Cell sorting to investigate T. cruzi infection as a trigger of vasculitis.
Fri Apr 01 00:00:00 EDT 2016
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
Nature communications
Ruhland MK,Loza AJ,Capietto AH,Luo X,Knolhoff BL,Flanagan KC,Belt BA,Alspach E,Leahy K,Luo J,Schaffer A,Edwards JR,Longmore G,Faccio R,DeNardo DG,Stewart SA
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Wed Jun 08 00:00:00 EDT 2016
Ranitidine modifies myeloid cell populations and inhibits breast tumor development and spread in mice.
Oncoimmunology
Vila-Leahey A,Oldford SA,Marignani PA,Wang J,Haidl ID,Marshall JS
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Fri Jul 01 00:00:00 EDT 2016
The impact of ranitidine on monocyte responses in the context of solid tumors.
Oncotarget
Vila-Leahey A,Rogers D,Marshall JS
25-5932 was used in Flow cytometry/Cell sorting to examine the impact of oral ranitidine treatment on multiple murine tumour models.
Tue Mar 08 00:00:00 EST 2016
Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.
Scientific reports
Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Wed Jun 15 00:00:00 EDT 2016
Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke.
Nature communications
Szalay G,Martinecz B,Lénárt N,Környei Z,Orsolits B,Judák L,Császár E,Fekete R,West BL,Katona G,Rózsa B,Dénes Á
25-5932 was used in Flow cytometry/Cell sorting to investigate the influence of microglia on neuronal activity and survival in the injured brain in vivo.
Tue May 03 00:00:00 EDT 2016
Obesity-associated NLRC4 inflammasome activation drives breast cancer progression.
Nature communications
Kolb R,Phan L,Borcherding N,Liu Y,Yuan F,Janowski AM,Xie Q,Markan KR,Li W,Potthoff MJ,Fuentes-Mattei E,Ellies LG,Knudson CM,Lee MH,Yeung SJ,Cassel SL,Sutterwala FS,Zhang W
25-5932 was used in Flow cytometry/Cell sorting to provide a causal mechanism by which obesity promotes breast cancer progression and lay out a foundation to block NLRC4 inflammasome activation or IL-1β signalling transduction for the treatment of obese cancer patients.
Thu Oct 06 00:00:00 EDT 2016
Cysteine cathepsin activity suppresses osteoclastogenesis of myeloid-derived suppressor cells in breast cancer.
Oncotarget
Edgington-Mitchell LE,Rautela J,Duivenvoorden HM,Jayatilleke KM,van der Linden WA,Verdoes M,Bogyo M,Parker BS
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2015
Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.
PloS one
Szulzewsky F,Pelz A,Feng X,Synowitz M,Markovic D,Langmann T,Holtman IR,Wang X,Eggen BJ,Boddeke HW,Hambardzumyan D,Wolf SA,Kettenmann H
Published figure using Ly-6C monoclonal antibody (Product # 25-5932-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2016