Product References
A combination of genetically engineered oncolytic virus and melittin-CpG for cancer viro-chemo-immunotherapy.
BMC medicine
Bahreyni A,Liu H,Mohamud Y,Xue YC,Fan YM,Zhang YL,Luo H
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Immunohistochemistry
Wed May 24 00:00:00 EDT 2023
Protocol for PPP1R15A-inhibited mouse model establishment with subcutaneous B16F1 tumor and single-cell analysis.
STAR protocols
Wang R,Wang M,Pei S,Zhang Y,Guo S,Guo W,Wu Z,Wang H,Li Y,Zhu Y,Meng LH,Lang J,Jin G,Xiao Y,Hu L,Kong X
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Fri Dec 15 00:00:00 EST 2023
MCL-1 Inhibitor S63845 Distinctively Affects Intramedullary and Extramedullary Hematopoiesis.
Pharmaceutics
Zhang H,Li F,Yang M,Zhang W,He M,Xu H,Wang C,Zhang Y,Wang W,Gao Y,Du X,Li Y
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Tue Mar 28 00:00:00 EDT 2023
Targeting adrenergic receptors to mitigate invariant natural killer T cells-induced acute liver injury.
iScience
Gonzatti MB,Freire BM,Antunes MM,de Menezes GB,Talbot J,Peron JPS,Basso AS,Keller AC
11-5941-82 was used in Flow Cytometry to suggest that the modulation of the adrenergic signaling can be a complementary approach to αGC-based immunotherapy to mitigate iNKT-induced liver injury without compromising its antitumoral activity.
Fri Oct 20 00:00:00 EDT 2023
Peripheral Neutrophils-Derived Matrix Metallopeptidase-9 Induces Postoperative Cognitive Dysfunction in Aged Mice.
Frontiers in aging neuroscience
Huang L,Tian W,Chen X,Xu H,Dai W,Zhang Y,Wu X,Yu W,Tian J,Su D
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Mon Mar 14 00:00:00 EDT 2022
NK cells require immune checkpoint receptor LILRB4/gp49B to control neurotropic Zika virus infections in mice.
JCI insight
Lee HN,Manangeeswaran M,Lewkowicz AP,Engel K,Chowdhury M,Garige M,Eckhaus MA,Sourbier C,Ireland DD,Verthelyi D
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Tue Feb 08 00:00:00 EST 2022
Valosin-containing protein (VCP/p97) inhibition reduces viral clearance and induces toxicity associated with muscular damage.
Cell death & disease
Del Rio Oliva M,Basler M
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
JAK1 signaling in dendritic cells promotes peripheral tolerance in autoimmunity through PD-L1-mediated regulatory T cell induction.
Cell reports
Vogel A,Martin K,Soukup K,Halfmann A,Kerndl M,Brunner JS,Hofmann M,Oberbichler L,Korosec A,Kuttke M,Datler H,Kieler M,Musiejovsky L,Dohnal A,Sharif O,Schabbauer G
11-5941-82 was used in Flow Cytometry to conclude that DC-intrinsic JAK1 promotes peripheral tolerance, suggesting potential unwarranted DC-mediated effects of Jakinibs in autoimmune diseases.
Tue Feb 22 00:00:00 EST 2022
Oncolytic vaccinia virus expressing a bispecific T-cell engager enhances immune responses in EpCAM positive solid tumors.
Frontiers in immunology
Wei M,Zuo S,Chen Z,Qian P,Zhang Y,Kong L,Gao H,Wei J,Dong J
11-5941-82 was used in Flow cytometry/Cell sorting to show that VV-EpCAM BiTE sophistically combines the antitumor advantages of bispecific antibodies and oncolytic viruses, which provides preclinical evidence for the therapeutic potential of VV-EpCAM BiTE.
Fri Dec 02 00:00:00 EST 2022
The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude.
The Journal of experimental medicine
Li ZY,Morman RE,Hegermiller E,Sun M,Bartom ET,Maienschein-Cline M,Sigvardsson M,Kee BL
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Mon Jun 07 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Fasudil prevents liver fibrosis via activating natural killer cells and suppressing hepatic stellate cells.
World journal of gastroenterology
Han QJ,Mu YL,Zhao HJ,Zhao RR,Guo QJ,Su YH,Zhang J
11-5941-82 was used in Flow cytometry/Cell sorting to evaluate the anti-fibrotic effects of Fasudil in a mouse model of liver fibrosis induced by thioacetamide.
Mon Jun 28 00:00:00 EDT 2021
The Effect of miR-520b on Macrophage Polarization and T Cell Immunity by Targeting PTEN in Breast Cancer.
Journal of oncology
Zhu Q,Yuan J,He Y,Hu Y
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Immunohistochemistry
Wed Apr 27 00:00:00 EDT 2022
Exosomal lncRNA SNHG10 derived from colorectal cancer cells suppresses natural killer cell cytotoxicity by upregulating INHBC.
Cancer cell international
Huang Y,Luo Y,Ou W,Wang Y,Dong D,Peng X,Luo Y
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Expression of CCRL2 Inhibits Tumor Growth by Concentrating Chemerin and Inhibiting Neoangiogenesis.
Cancers
Al Delbany D,Robert V,Dubois-Vedrenne I,Del Prete A,Vernimmen M,Radi A,Lefort A,Libert F,Wittamer V,Sozzani S,Parmentier M
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Tue Oct 05 00:00:00 EDT 2021
Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials.
EBioMedicine
Okada R,Furusawa A,Vermeer DW,Inagaki F,Wakiyama H,Kato T,Nagaya T,Choyke PL,Spanos WC,Allen CT,Kobayashi H
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
A novel miR1983-TLR7-IFNβ circuit licenses NK cells to kill glioma cells, and is under the control of galectin-1.
Oncoimmunology
Shah D,Comba A,Faisal SM,Kadiyala P,Baker GJ,Alghamri MS,Doherty R,Zamler D,Nuñez G,Castro MG,Lowenstein PR
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation.
eLife
Wilfahrt D,Philips RL,Lama J,Kizerwetter M,Shapiro MJ,McCue SA,Kennedy MM,Rajcula MJ,Zeng H,Shapiro VS
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Protein Assays and Analysis
Thu Dec 02 00:00:00 EST 2021
Sequencing, cloning, and antigen binding analysis of monoclonal antibodies isolated from single mouse B cells.
STAR protocols
Viant C,Escolano A,Chen ST,Nussenzweig MC
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Fri Jun 18 00:00:00 EDT 2021
The enrichment of neutrophil extracellular traps impair the placentas of systemic lupus erythematosus through accumulating decidual NK cells.
Scientific reports
Jiang M,Shen N,Zhou H,Wang Y,Lin S,Wu J,Di W
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Thu Mar 25 00:00:00 EDT 2021
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist.
eLife
Glassman CR,Su L,Majri-Morrison SS,Winkelmann H,Mo F,Li P,Pérez-Cruz M,Ho PP,Koliesnik I,Nagy N,Hnizdilova T,Picton LK,Kovar M,Bollyky P,Steinman L,Meyer E,Piehler J,Leonard WJ,Garcia KC
11-5941 was used in Flow cytometry/Cell sorting to show that cytokine partial agonists can be used to calibrate intrinsic differences in response thresholds across responding cell types to narrow pleiotropic actions, which may be generalizable to other cytokine and growth factor systems.
Tue May 18 00:00:00 EDT 2021
An engineered oncolytic vaccinia virus encoding a single-chain variable fragment against TIGIT induces effective antitumor immunity and synergizes with PD-1 or LAG-3 blockade.
Journal for immunotherapy of cancer
Zuo S,Wei M,Xu T,Kong L,He B,Wang S,Wang S,Wu J,Dong J,Wei J
11-5941-82 was used in Flow cytometry/Cell sorting to conclude that oncolytic virotherapy using engineered VV-scFv-TIGIT was an effective strategy for cancer immunotherapy.
Wed Dec 01 00:00:00 EST 2021
Astrocytes promote a protective immune response to brain Toxoplasma gondii infection via IL-33-ST2 signaling.
PLoS pathogens
Still KM,Batista SJ,O'Brien CA,Oyesola OO,Früh SP,Webb LM,Smirnov I,Kovacs MA,Cowan MN,Hayes NW,Thompson JA,Tait Wojno ED,Harris TH
11-5941 was used in Flow cytometry/Cell sorting to show that IL-33 is expressed by oligodendrocytes and astrocytes during T. gondii infection, is released locally into the cerebrospinal fluid of T. gondii-infected animals, and is required for control of infection.
Thu Oct 01 00:00:00 EDT 2020
MicroRNA-9 Fine-Tunes Dendritic Cell Function by Suppressing Negative Regulators in a Cell-Type-Specific Manner.
Cell reports
Cordeiro B,Jeon P,Boukhaled GM,Corrado M,Lapohos O,Roy DG,Williams K,Jones RG,Gruenheid S,Sagan SM,Krawczyk CM
11-5941 was used in Flow cytometry/Cell sorting to demonstrate that miR-9 facilitates the transition of DCs from steady state to mature state by regulating the expression of several negative regulators of DC function in a cell-type-specific manner.
Tue May 05 00:00:00 EDT 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Fri Jun 19 00:00:00 EDT 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Fri Jun 19 00:00:00 EDT 2020
ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms.
Cell reports
Viaud M,Abdel-Wahab O,Gall J,Ivanov S,Guinamard R,Sore S,Merlin J,Ayrault M,Guilbaud E,Jacquel A,Auberger P,Wang N,Levine RL,Tall AR,Yvan-Charvet L
11-5941 was used in Flow cytometry/Cell sorting to identify somatic mutations in ABCA1 that subvert its anti-proliferative and cholesterol efflux functions and permit the progression of myeloid neoplasms.
Tue Mar 10 00:00:00 EDT 2020
Neurokinin-1 Receptor Signaling Is Required for Efficient Ca2+ Flux in T-Cell-Receptor-Activated T Cells.
Cell reports
Morelli AE,Sumpter TL,Rojas-Canales DM,Bandyopadhyay M,Chen Z,Tkacheva O,Shufesky WJ,Wallace CT,Watkins SC,Berger A,Paige CJ,Falo LD,Larregina AT
11-5941 was used in Flow cytometry/Cell sorting to demonstrate an effect of the NK1R in T cells that is relevant for immunotherapies based on pro-inflammatory neuropeptides and its receptors.
Tue Mar 10 00:00:00 EDT 2020
Dendritic Cells and Myeloid Derived Suppressor Cells Fully Responsive to Stimulation via Toll-Like Receptor 4 Are Rapidly Induced from Bone-Marrow Cells by Granulocyte-Macrophage Colony-Stimulating Factor.
Vaccines
Kong YY,Wilson K,Apostolopoulos V,Plebanski M
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Sat Sep 12 00:00:00 EDT 2020
Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature
Escolano A,Gristick HB,Abernathy ME,Merkenschlager J,Gautam R,Oliveira TY,Pai J,West AP,Barnes CO,Cohen AA,Wang H,Golijanin J,Yost D,Keeffe JR,Wang Z,Zhao P,Yao KH,Bauer J,Nogueira L,Gao H,Voll AV,Montefiori DC,Seaman MS,Gazumyan A,Silva M,McGuire AT,Stamatatos L,Irvine DJ,Wells L,Martin MA,Bjorkman PJ,Nussenzweig MC
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Sat Jun 01 00:00:00 EDT 2019
Deletion of C-C Motif Chemokine Ligand 5 Worsens Invariant Natural Killer T-Cell-Mediated Hepatitis via Compensatory Up-regulation of CXCR2-Related Chemokine Activity.
Cellular and molecular gastroenterology and hepatology
Chen L,Gu J,Qian Y,Li M,Qian Y,Xu M,Li J,Wen Y,Xia L,Li J,Xia Q,Kong X,Wu H
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Tue Jun 04 00:00:00 EDT 2019
Synergized regulation of NK cell education by NKG2A and specific Ly49 family members.
Nature communications
Zhang X,Feng J,Chen S,Yang H,Dong Z
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2019
Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells.
JCI insight
Huang A,Shinde PV,Huang J,Senff T,Xu HC,Margotta C,Häussinger D,Willnow TE,Zhang J,Pandyra AA,Timm J,Weggen S,Lang KS,Lang PA
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Thu Sep 05 00:00:00 EDT 2019
Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia.
Nature communications
Hayashi Y,Goyama S,Liu X,Tamura M,Asada S,Tanaka Y,Fukuyama T,Wunderlich M,O'Brien E,Mizukawa B,Yamazaki S,Matsumoto A,Yamasaki S,Shibata T,Matsuda K,Sashida G,Takizawa H,Kitamura T
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Fri Oct 25 00:00:00 EDT 2019
Myeloid Cells Restrict MCMV and Drive Stress-Induced Extramedullary Hematopoiesis through STAT1.
Cell reports
Gawish R,Bulat T,Biaggio M,Lassnig C,Bago-Horvath Z,Macho-Maschler S,Poelzl A,Simonović N,Prchal-Murphy M,Rom R,Amenitsch L,Ferrarese L,Kornhoff J,Lederer T,Svinka J,Eferl R,Bosmann M,Kalinke U,Stoiber D,Sexl V,Krmpotić A,Jonjić S,Müller M,Strobl B
11-5941 was used in Flow cytometry/Cell sorting to provide genetic evidence that signaling through STAT1 in myeloid cells is required to restrict MCMV at early time points post-infection and to induce compensatory hematopoiesis in the spleen.
Tue Feb 26 00:00:00 EST 2019
Virus-Induced Interferon-γ Causes Insulin Resistance in Skeletal Muscle and Derails Glycemic Control in Obesity.
Immunity
Šestan M,Marinović S,Kavazović I,Cekinović Đ,Wueest S,Turk Wensveen T,Brizić I,Jonjić S,Konrad D,Wensveen FM,Polić B
11-5941 was used in Flow cytometry/Cell sorting to study how viral infection effects insulin resistance.
Tue Jul 17 00:00:00 EDT 2018
Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells.
Immunity
Hu G,Cui K,Fang D,Hirose S,Wang X,Wangsa D,Jin W,Ried T,Liu P,Zhu J,Rothenberg EV,Zhao K
11-5941 was used in Flow cytometry/Cell sorting to find that abrupt genome-wide changes at all three levels of chromatin organization occur during the transition from double-negative stage 2 (DN2) to DN3, accompanying the T lineage commitment.
Tue Feb 20 00:00:00 EST 2018
Dysregulation of Kupffer Cells/Macrophages and Natural Killer T Cells in Steatohepatitis in LXRα Knockout Male Mice.
Endocrinology
Endo-Umeda K,Nakashima H,Umeda N,Seki S,Makishima M
11-5941 was used in Flow cytometry/Cell sorting to study the role fof LXRα in the pathogenesis of steatohepatitis.
Thu Mar 01 00:00:00 EST 2018
CD8+ T cells mediate the antitumor activity of frankincense and myrrh in hepatocellular carcinoma.
Journal of translational medicine
Xu C,Lu X,Liu W,Chen A,Meng G,Zhang H,Li B,Zhang Y,Wu J,Wei J
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Mon May 21 00:00:00 EDT 2018
Plasmodium co-infection protects against chikungunya virus-induced pathologies.
Nature communications
Teo TH,Lum FM,Ghaffar K,Chan YH,Amrun SN,Tan JJL,Lee CYP,Chua TK,Carissimo G,Lee WWL,Claser C,Rajarethinam R,Rénia L,Ng LFP
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Tue Sep 25 00:00:00 EDT 2018
Type 2 Innate Lymphocytes Actuate Immunity Against Tumours and Limit Cancer Metastasis.
Scientific reports
Saranchova I,Han J,Zaman R,Arora H,Huang H,Fenninger F,Choi KB,Munro L,Pfeifer CG,Welch I,Takei F,Jefferies WA
11-5941 was used in Flow cytometry/Cell sorting to study the role of type 2 innate lymphoid cells in enhancing anti-cancer immunity and controlling metastasis.
Tue Feb 13 00:00:00 EST 2018
Group 2 innate lymphoid cells protect lung endothelial cells from pyroptosis in sepsis.
Cell death & disease
Lai D,Tang J,Chen L,Fan EK,Scott MJ,Li Y,Billiar TR,Wilson MA,Fang X,Shu Q,Fan J
11-5941 was used in Flow cytometry/Cell sorting to describe the function of ILC2 in the regulation of lung inflammation by protecting lung endothelial cell from pyroptosis.
Tue Mar 06 00:00:00 EST 2018
Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate.
Cell
Isoda T,Moore AJ,He Z,Chandra V,Aida M,Denholtz M,Piet van Hamburg J,Fisch KM,Chang AN,Fahl SP,Wiest DL,Murre C
11-5941 was used in Flow cytometry/Cell sorting to study the repositioning of the Bcl11b enhancer to dictate the fate of developing T cells.
Thu Sep 21 00:00:00 EDT 2017
Differentiation of human and murine induced pluripotent stem cells to microglia-like cells.
Nature neuroscience
Pandya H,Shen MJ,Ichikawa DM,Sedlock AB,Choi Y,Johnson KR,Kim G,Brown MA,Elkahloun AG,Maric D,Sweeney CL,Gossa S,Malech HL,McGavern DB,Park JK
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
Maintaining unperturbed cerebral blood flow is key in the study of brain metastasis and its interactions with stress and inflammatory responses.
Brain, behavior, and immunity
Benbenishty A,Segev-Amzaleg N,Shaashua L,Melamed R,Ben-Eliyahu S,Blinder P
11-5941 was used in Flow cytometry/Cell sorting to demonstrate the importance of maintaining unperturbed cerebral blood flow while studying brain metastasis and interactions with stress and inflammatory responses.
Mon May 01 00:00:00 EDT 2017
A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells.
Leukemia
Cheadle EJ,Lipowska-Bhalla G,Dovedi SJ,Fagnano E,Klein C,Honeychurch J,Illidge TM
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Sat Jul 01 00:00:00 EDT 2017
Bacillus anthracis lethal toxin negatively modulates ILC3 function through perturbation of IL-23-mediated MAPK signaling.
PLoS pathogens
Seshadri S,Allan DSJ,Carlyle JR,Zenewicz LA
11-5941 was used in Flow cytometry/Cell sorting to study the effects of MAPK signalling pathways in group 3 innate immune lymphocytes using Bacillus anthracis.
Sun Oct 01 00:00:00 EDT 2017
Adenoviral production of interleukin-2 at the tumor site removes the need for systemic postconditioning in adoptive cell therapy.
International journal of cancer
Santos JM,Havunen R,Siurala M,Cervera-Carrascon V,Tähtinen S,Sorsa S,Anttila M,Karell P,Kanerva A,Hemminki A
11-5941-82 was used in Flow Cytometry to study the efficacy and safety of intratumorally administered IL-2 coding adenoviruses in combination with lymphocyte therapy in Syrian hamsters bearing pancreatic tumours.
Sun Oct 01 00:00:00 EDT 2017
Toll like Receptor 2 engagement on CD4+ T cells promotes TH9 differentiation and function.
European journal of immunology
Karim AF,Reba SM,Li Q,Boom WH,Rojas RE
11-5941 was used in Flow cytometry/Cell sorting to study the role of T-cell expressed TLR2 on CD4+ T-cell differentiation and function.
Fri Sep 01 00:00:00 EDT 2017
Regulatory T Cells Promote Myositis and Muscle Damage in Toxoplasma gondii Infection.
Journal of immunology (Baltimore, Md. : 1950)
Jin RM,Blair SJ,Warunek J,Heffner RR,Blader IJ,Wohlfert EA
11-5941 was used in Flow cytometry/Cell sorting to study how the tissue environment established by Toxoplasma gondii leads to a pathogenic role for regulatory T cells.
Sun Jan 01 00:00:00 EST 2017
Retinoic Acid Regulates Immune Responses by Promoting IL-22 and Modulating S100 Proteins in Viral Hepatitis.
Journal of immunology (Baltimore, Md. : 1950)
Jie Z,Liang Y,Yi P,Tang H,Soong L,Cong Y,Zhang K,Sun J
11-5941 was used in Flow cytometry/Cell sorting to determine the role of retinoic acid in IL-22 production during hepatitis infection.
Mon May 01 00:00:00 EDT 2017
IL-2/Anti-IL-2 Complex Attenuates Inflammation and BBB Disruption in Mice Subjected to Traumatic Brain Injury.
Frontiers in neurology
Gao W,Li F,Zhou Z,Xu X,Wu Y,Zhou S,Yin D,Sun D,Xiong J,Jiang R,Zhang J
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Loss of HIF-1α in natural killer cells inhibits tumour growth by stimulating non-productive angiogenesis.
Nature communications
Krzywinska E,Kantari-Mimoun C,Kerdiles Y,Sobecki M,Isagawa T,Gotthardt D,Castells M,Haubold J,Millien C,Viel T,Tavitian B,Takeda N,Fandrey J,Vivier E,Sexl V,Stockmann C
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Fri Nov 17 00:00:00 EST 2017
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Hypoxia-Inducible Factor-2α Limits Natural Killer T Cell Cytotoxicity in Renal Ischemia/Reperfusion Injury.
Journal of the American Society of Nephrology : JASN
Zhang J,Han C,Dai H,Hou J,Dong Y,Cui X,Xu L,Zhang M,Xia Q
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
Mast cell depletion in the preclinical phase of collagen-induced arthritis reduces clinical outcome by lowering the inflammatory cytokine profile.
Arthritis research & therapy
van der Velden D,Lagraauw HM,Wezel A,Launay P,Kuiper J,Huizinga TW,Toes RE,Bot I,Stoop JN
11-5941 was used in Flow cytometry/Cell sorting to suggest that mast cells may play a role in the regulation of the adaptive immune response during the development of arthritis.
Mon Jun 13 00:00:00 EDT 2016
Flt3 Ligand Regulates the Development of Innate Lymphoid Cells in Fetal and Adult Mice.
Journal of immunology (Baltimore, Md. : 1950)
Baerenwaldt A,von Burg N,Kreuzaler M,Sitte S,Horvath E,Peter A,Voehringer D,Rolink AG,Finke D
11-5941 was used in Flow cytometry/Cell sorting to investigate the role of the Flt3 ligand in the development and regulation of innate lymphoid cells in fetal and adult mice.
Tue Mar 15 00:00:00 EDT 2016
NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Nature communications
Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Wed Sep 07 00:00:00 EDT 2016
Tumor sialylation impedes T cell mediated anti-tumor responses while promoting tumor associated-regulatory T cells.
Oncotarget
Perdicchio M,Cornelissen LA,Streng-Ouwehand I,Engels S,Verstege MI,Boon L,Geerts D,van Kooyk Y,Unger WW
11-5941 was used in Flow cytometry/Cell sorting to study the influence of B16 melanoma hypersialylation on tumour growth.
Tue Feb 23 00:00:00 EST 2016
CXCL16-positive dendritic cells enhance invariant natural killer T cell-dependent IFNγ production and tumor control.
Oncoimmunology
Veinotte L,Gebremeskel S,Johnston B
11-5941 was used in Flow cytometry/Cell sorting to study the co-stimulatory role of CXCR6/CXCL16 interactions in glycolipid-dependent invariant natural killer T (iNKT) cell activation and tumour control, showing that CXCL16-positive dendritic cells enhance iNKT cell-dependent IFNγ production and tumor control.
Wed Jun 01 00:00:00 EDT 2016
Proteinase 3 on apoptotic cells disrupts immune silencing in autoimmune vasculitis.
The Journal of clinical investigation
Millet A,Martin KR,Bonnefoy F,Saas P,Mocek J,Alkan M,Terrier B,Kerstein A,Tamassia N,Satyanarayanan SK,Ariel A,Ribeil JA,Guillevin L,Cassatella MA,Mueller A,Thieblemont N,Lamprecht P,Mouthon L,Perruche S,Witko-Sarsat V
11-5941 was used in Flow cytometry/Cell sorting to investigate disruption of immune silencing by proteinase 3 on apoptotic cells.
Mon Nov 02 00:00:00 EST 2015
Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells.
The Journal of clinical investigation
Hadland BK,Varnum-Finney B,Poulos MG,Moon RT,Butler JM,Rafii S,Bernstein ID
11-5941 was used in Flow cytometry/Cell sorting to investigate the critical niche components and resident signals required for hematopoietic stem cell induction and self-renewal ex vivo.
Fri May 01 00:00:00 EDT 2015
The Flavonoid Isoliquiritigenin Reduces Lung Inflammation and Mouse Morbidity during Influenza Virus Infection.
Antimicrobial agents and chemotherapy
Traboulsi H,Cloutier A,Boyapelly K,Bonin MA,Marsault É,Cantin AM,Richter MV
11-5941 was used in Flow cytometry/Cell sorting to investigate the anti-inflammatory and antiviral activities of isoliquiritigenin during influenza virus infection.
Thu Oct 01 00:00:00 EDT 2015
Diverse roles for T-bet in the effector responses required for resistance to infection.
Journal of immunology (Baltimore, Md. : 1950)
Harms Pritchard G,Hall AO,Christian DA,Wagage S,Fang Q,Muallem G,John B,Glatman Zaretsky A,Dunn WG,Perrigoue J,Reiner SL,Hunter CA
11-5941 was used in Flow cytometry/Cell sorting to highlight T-bet-independent pathways to IFN-γ production and reveal a novel role for this transcription factor in coordinating the T cell responses necessary to control infection in peripheral tissues.
Sun Feb 01 00:00:00 EST 2015
Spred1, a Suppressor of the Ras-ERK Pathway, Negatively Regulates Expansion and Function of Group 2 Innate Lymphoid Cells.
Journal of immunology (Baltimore, Md. : 1950)
Suzuki M,Morita R,Hirata Y,Shichita T,Yoshimura A
11-5941 was used in Flow cytometry/Cell sorting to demonstrate that Spred1, a negative regulator of the Ras-ERK pathway, plays an important role in the proliferation and apoptosis of ILC2s and in cytokine secretion from ILC2s.
Sat Aug 01 00:00:00 EDT 2015
Toll-Like receptor 2 (TLR2) and TLR9 play opposing roles in host innate immunity against Salmonella enterica serovar Typhimurium infection.
Infection and immunity
Zhan R,Han Q,Zhang C,Tian Z,Zhang J
11-5941 was used in Flow cytometry/Cell sorting to investigate the roles of TLR2 and TLR9 in regulating innate immunity against oral infection of Salmonella enterica serovar Typhimurium in mice.
Wed Apr 01 00:00:00 EDT 2015
Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.
PloS one
Tähtinen S,Kaikkonen S,Merisalo-Soikkeli M,Grönberg-Vähä-Koskela S,Kanerva A,Parviainen S,Vähä-Koskela M,Hemminki A
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Thu Apr 28 00:00:00 EDT 2016
Metronomic cyclophosphamide eradicates large implanted GL261 gliomas by activating antitumor Cd8+ T-cell responses and immune memory.
Oncoimmunology
Wu J,Waxman DJ
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Microbiota modulate tumoral immune surveillance in lung through a γδT17 immune cell-dependent mechanism.
Cancer research
Cheng M,Qian L,Shen G,Bian G,Xu T,Xu W,Shen G,Hu S
11-5941 was used in Flow cytometry/Cell sorting to investigate the mechanism by which commensal bacteria modulate the efficiency of tumoral immune surveillance in mucosal tissues.
Fri Aug 01 00:00:00 EDT 2014
IL-17-producing NKT cells depend exclusively on IL-7 for homeostasis and survival.
Mucosal immunology
Webster KE,Kim HO,Kyparissoudis K,Corpuz TM,Pinget GV,Uldrich AP,Brink R,Belz GT,Cho JH,Godfrey DI,Sprent J
11-5941 was used in Flow cytometry/Cell sorting to elucidate the factors that maintain the natural killer T cell population in the periphery.
Mon Sep 01 00:00:00 EDT 2014
Parasite fate and involvement of infected cells in the induction of CD4+ and CD8+ T cell responses to Toxoplasma gondii.
PLoS pathogens
Dupont CD,Christian DA,Selleck EM,Pepper M,Leney-Greene M,Harms Pritchard G,Koshy AA,Wagage S,Reuter MA,Sibley LD,Betts MR,Hunter CA
11-5941 was used in Flow cytometry/Cell sorting to identify a critical role for actively infected host cells in initiating T. gondii-specific CD4+ and CD8+ T cell responses.
Tue Apr 01 00:00:00 EDT 2014
TLR2 engagement on CD4(+) T cells enhances effector functions and protective responses to Mycobacterium tuberculosis.
European journal of immunology
Reba SM,Li Q,Onwuzulike S,Ding X,Karim AF,Hernandez Y,Fulton SA,Harding CV,Lancioni CL,Nagy N,Rodriguez ME,Wearsch PA,Rojas RE
11-5941-82 was used in Flow cytometry/Cell sorting to examine the role of CD4(+) T-cell-expressed TLR2 in Mycobacterium tuberculosis (MTB) Ag-specific T-cell priming and in protection against MTB infection in vivo.
Thu May 01 00:00:00 EDT 2014
17β-estradiol protects females against influenza by recruiting neutrophils and increasing virus-specific CD8 T cell responses in the lungs.
Journal of virology
Robinson DP,Hall OJ,Nilles TL,Bream JH,Klein SL
11-5941 was used in Flow cytometry/Cell sorting to demonstrate that estradiol is a potent anti-inflammatory hormone that reduces the severity of influenza A virus infection in females.
Thu May 01 00:00:00 EDT 2014
Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in viral infection.
Journal of immunology (Baltimore, Md. : 1950)
Jie Z,Liang Y,Hou L,Dong C,Iwakura Y,Soong L,Cong Y,Sun J
11-5941 was used in Flow cytometry/Cell sorting to investigate the source and regulation of the IL-17 surge in the liver microenvironment that occurs early in the response to viral infection.
Tue Apr 01 00:00:00 EDT 2014
Differential requirement for CCR4 and CCR7 during the development of innate and adaptive αβT cells in the adult thymus.
Journal of immunology (Baltimore, Md. : 1950)
Cowan JE,McCarthy NI,Parnell SM,White AJ,Bacon A,Serge A,Irla M,Lane PJ,Jenkinson EJ,Jenkinson WE,Anderson G
11-5941 was used in Flow cytometry/Cell sorting to identify novel roles for CCR7 during intrathymic T cell development, highlighting its importance in enabling multiple αβT cell lineages to access the thymic medulla.
Fri Aug 01 00:00:00 EDT 2014
Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface.
PloS one
Habbeddine M,Verbeke P,Karaz S,Bobé P,Kanellopoulos-Langevin C
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Wed Jun 10 00:00:00 EDT 2015
Perturbation of NK cell peripheral homeostasis accelerates prostate carcinoma metastasis.
The Journal of clinical investigation
Liu G,Lu S,Wang X,Page ST,Higano CS,Plymate SR,Greenberg NM,Sun S,Li Z,Wu JD
11-5941 was used in Flow cytometry/Cell sorting to provide evidence in vivo that soluble and membrane-restricted NKG2D ligands pose opposite impacts on cancer progression.
Tue Oct 01 00:00:00 EDT 2013
Host immunity contributes to the anti-melanoma activity of BRAF inhibitors.
The Journal of clinical investigation
Knight DA,Ngiow SF,Li M,Parmenter T,Mok S,Cass A,Haynes NM,Kinross K,Yagita H,Koya RC,Graeber TG,Ribas A,McArthur GA,Smyth MJ
11-5941 was used in Flow cytometry/Cell sorting to investigate the contribution of host immunity to the anti-melanoma activity of BRAF inhibitors.
Fri Mar 01 00:00:00 EST 2013
Lipidoid Nanoparticles Containing PD-L1 siRNA Delivered In Vivo Enter Kupffer Cells and Enhance NK and CD8(+) T Cell-mediated Hepatic Antiviral Immunity.
Molecular therapy. Nucleic acids
Dolina JS,Sung SS,Novobrantseva TI,Nguyen TM,Hahn YS
11-5941 was used in Flow cytometry/Cell sorting to demonstrate that PD-L1 knockdown on KCs is central in determining the outcome of liver viral infections, and they represent a new class of gene therapy.
Tue Feb 19 00:00:00 EST 2013
A new immuno-, dystrophin-deficient model, the NSG-mdx(4Cv) mouse, provides evidence for functional improvement following allogeneic satellite cell transplantation.
Stem cells (Dayton, Ohio)
Arpke RW,Darabi R,Mader TL,Zhang Y,Toyama A,Lonetree CL,Nash N,Lowe DA,Perlingeiro RC,Kyba M
11-5941 was used in Flow cytometry/Cell sorting to highlight the potency of satellite cells to improve muscle function and the utility of the NSG-mdx(4Cv) model for studies on muscle regeneration.
Thu Aug 01 00:00:00 EDT 2013
Cutting edge: IL-25 elicits innate lymphoid type 2 and type II NKT cells that regulate obesity in mice.
Journal of immunology (Baltimore, Md. : 1950)
Hams E,Locksley RM,McKenzie AN,Fallon PG
11-5941 was used in Flow cytometry/Cell sorting to investigate the role of IL-25-responsive innate cells in regulating weight and glucose homeostasis.
Sun Dec 01 00:00:00 EST 2013
Glucocorticoid receptor-dependent immunomodulatory effect of ursodeoxycholic acid on liver lymphocytes in mice.
American journal of physiology. Gastrointestinal and liver physiology
Takigawa T,Miyazaki H,Kinoshita M,Kawarabayashi N,Nishiyama K,Hatsuse K,Ono S,Saitoh D,Seki S,Yamamoto J
11-5941 was used in Flow cytometry/Cell sorting to investigate the immunomodulatory effect of ursodeoxycholic acid on experimental hepatitis, endotoxin shock, and bacterial infection in mice.
Sun Sep 15 00:00:00 EDT 2013
VEGF receptor inhibitors block the ability of metronomically dosed cyclophosphamide to activate innate immunity-induced tumor regression.
Cancer research
Doloff JC,Waxman DJ
Published figure using NK1.1 monoclonal antibody (Product # 11-5941-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2012
Unexpected role for MHC II-peptide complexes in shaping CD8 T-cell expansion and differentiation in vivo.
Proceedings of the National Academy of Sciences of the United States of America
Do JS,Valujskikh A,Vignali DA,Fairchild RL,Min B
11-5941 was used in Flow cytometry/Cell sorting to reveal a previously undefined MHC II-dependent regulation that tunes CD8 T-cell reactivity.
Tue Jul 31 00:00:00 EDT 2012
Augmentation of natural cytotoxicity by chronic low-dose ionizing radiation in murine natural killer cells primed by IL-2.
Journal of radiation research
Sonn CH,Choi JR,Kim TJ,Yu YB,Kim K,Shin SC,Park GH,Shirakawa T,Kim HS,Lee KM
11-5941 was used in Flow cytometry/Cell sorting to demonstrate how exposure to LDR can lead to subtle immune-enhancing effects on NK cells.
Thu Nov 01 00:00:00 EDT 2012
PML-RARA can increase hematopoietic self-renewal without causing a myeloproliferative disease in mice.
The Journal of clinical investigation
Welch JS,Yuan W,Ley TJ
11-5941 was used in Flow cytometry/Cell sorting to study a platform for more accurately dissecting the early events in acute promyelocytic leukemia pathogenesis.
Fri Apr 01 00:00:00 EDT 2011
Bioluminescent imaging reveals divergent viral pathogenesis in two strains of Stat1-deficient mice, and in αßγ interferon receptor-deficient mice.
PloS one
Pasieka TJ,Collins L,O'Connor MA,Chen Y,Parker ZM,Berwin BL,Piwnica-Worms DR,Leib DA
11-5941 was used in Flow cytometry/Cell sorting to examine HSV-1 pathogenesis in Stat1(-/-) mice and in IFNαβγR(-/-) mice, showing divergent viral pathogenesis between mouse strains.
Tue Feb 14 00:00:00 EST 2012
CD169(+) macrophages present lipid antigens to mediate early activation of iNKT cells in lymph nodes.
Nature immunology
Barral P,Polzella P,Bruckbauer A,van Rooijen N,Besra GS,Cerundolo V,Batista FD
11-5941 was used in Flow cytometry/Cell sorting to investigate how and where invariant natural killer T cells encounter antigens in vivo.
Thu Apr 01 00:00:00 EDT 2010
Cutting edge: spontaneous development of IL-17-producing gamma delta T cells in the thymus occurs via a TGF-beta 1-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950)
Do JS,Fink PJ,Li L,Spolski R,Robinson J,Leonard WJ,Letterio JJ,Min B
11-5941 was used in Flow cytometry/Cell sorting to investigate the mechanisms underlying the generation of gammadelta T cells, showing that it occurs via a TGF-beta 1-dependent mechanism.
Mon Feb 15 00:00:00 EST 2010
Mice that overexpress human heat shock protein 27 have increased renal injury following ischemia reperfusion.
Kidney international
Chen SW,Kim M,Kim M,Song JH,Park SW,Wells D,Brown K,Belleroche Jd,D'Agati VD,Lee HT
11-5941 was used in Flow cytometry/Cell sorting to investigate increased renal injury in mice that overexpress human heat shock protein 27 following ischemia reperfusion.
Sun Mar 01 00:00:00 EST 2009
Yin-Yang 1 regulates effector cytokine gene expression and T(H)2 immune responses.
The Journal of allergy and clinical immunology
Guo J,Lin X,Williams MA,Hamid Q,Georas SN
Tue Jul 01 00:00:00 EDT 2008
Runx proteins are involved in regulation of CD122, Ly49 family and IFN-gamma expression during NK cell differentiation.
International immunology
Ohno S,Sato T,Kohu K,Takeda K,Okumura K,Satake M,Habu S
11-5941 was used in Flow cytometry/Cell sorting to investigate the role of Runx family proteins in NK cells, showing that they are involved in regulation of CD122, Ly49 family and IFN-gamma expression during differentiation.
Tue Jan 01 00:00:00 EST 2008
Role of natural killer cells in modulating dendritic cell responses to Leishmania amazonensis infection.
Infection and immunity
Sanabria MX,Vargas-Inchaustegui DA,Xin L,Soong L
11-5941 was used in Flow cytometry/Cell sorting to suggest differential roles of DC-NK cell cross talk at different stages of Leishmania infection.
Sat Nov 01 00:00:00 EDT 2008
The Pten/PI3K pathway governs the homeostasis of Valpha14iNKT cells.
Blood
Kishimoto H,Ohteki T,Yajima N,Kawahara K,Natsui M,Kawarasaki S,Hamada K,Horie Y,Kubo Y,Arase S,Taniguchi M,Vanhaesebroeck B,Mak TW,Nakano T,Koyasu S,Sasaki T,Suzuki A
11-5941 was used in Flow cytometry/Cell sorting to describe the phenotype of Pten-deficient Valpha14iNKT cells.
Sun Apr 15 00:00:00 EDT 2007
Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation.
The Journal of experimental medicine
Besseyrias V,Fiorini E,Strobl LJ,Zimber-Strobl U,Dumortier A,Koch U,Arcangeli ML,Ezine S,Macdonald HR,Radtke F
11-5941 was used in Flow cytometry/Cell sorting to study the Notch-Delta interactions that promote T cell development.
Mon Feb 19 00:00:00 EST 2007
Poly I:C prevents T cell-mediated hepatitis via an NK-dependent mechanism.
Journal of hepatology
Wang J,Sun R,Wei H,Dong Z,Gao B,Tian Z
11-5941 was used in Magnetic cell separation to study the prevention of T-cell mediated hepatitis by Poly I:C via an NK-dependent mechanism.
Wed Mar 01 00:00:00 EST 2006
T-bet concomitantly controls migration, survival, and effector functions during the development of Valpha14i NKT cells.
Blood
Matsuda JL,Zhang Q,Ndonye R,Richardson SK,Howell AR,Gapin L
11-5941 was used in Flow cytometry/Cell sorting to identify some of the genetic targets of T-bet during V14i NKT-cell lineage development.
Sat Apr 01 00:00:00 EST 2006
De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent.
Cancer cell
de Visser KE,Korets LV,Coussens LM
11-5941 was used in Flow cytometry/Cell sorting to suggest that B lymphocytes are required for establishing chronic inflammatory states that promote de novo carcinogenesis.
Sun May 01 00:00:00 EDT 2005
