Product References
A combination of genetically engineered oncolytic virus and melittin-CpG for cancer viro-chemo-immunotherapy.
BMC medicine
Bahreyni A,Liu H,Mohamud Y,Xue YC,Fan YM,Zhang YL,Luo H
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Immunohistochemistry (Paraffin)
Wed May 24 00:00:00 EDT 2023
Protocol for PPP1R15A-inhibited mouse model establishment with subcutaneous B16F1 tumor and single-cell analysis.
STAR protocols
Wang R,Wang M,Pei S,Zhang Y,Guo S,Guo W,Wu Z,Wang H,Li Y,Zhu Y,Meng LH,Lang J,Jin G,Xiao Y,Hu L,Kong X
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Fri Dec 15 00:00:00 EST 2023
MCL-1 Inhibitor S63845 Distinctively Affects Intramedullary and Extramedullary Hematopoiesis.
Pharmaceutics
Zhang H,Li F,Yang M,Zhang W,He M,Xu H,Wang C,Zhang Y,Wang W,Gao Y,Du X,Li Y
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Tue Mar 28 00:00:00 EDT 2023
Peripheral Neutrophils-Derived Matrix Metallopeptidase-9 Induces Postoperative Cognitive Dysfunction in Aged Mice.
Frontiers in aging neuroscience
Huang L,Tian W,Chen X,Xu H,Dai W,Zhang Y,Wu X,Yu W,Tian J,Su D
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Mon Mar 14 00:00:00 EDT 2022
NK cells require immune checkpoint receptor LILRB4/gp49B to control neurotropic Zika virus infections in mice.
JCI insight
Lee HN,Manangeeswaran M,Lewkowicz AP,Engel K,Chowdhury M,Garige M,Eckhaus MA,Sourbier C,Ireland DD,Verthelyi D
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Tue Feb 08 00:00:00 EST 2022
Valosin-containing protein (VCP/p97) inhibition reduces viral clearance and induces toxicity associated with muscular damage.
Cell death & disease
Del Rio Oliva M,Basler M
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes.
Nature
Maschalidi S,Mehrotra P,Keçeli BN,De Cleene HKL,Lecomte K,Van der Cruyssen R,Janssen P,Pinney J,van Loo G,Elewaut D,Massie A,Hoste E,Ravichandran KS
13-5941-82 was used in In vitro Assay to reveal that the membrane transporter SLC7A11 acts as a molecular brake on efferocytosis, the process by which dying cells are removed, and that inhibiting SLC7A11 function can accelerate wound healing.
Wed Jun 01 00:00:00 EDT 2022
The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude.
The Journal of experimental medicine
Li ZY,Morman RE,Hegermiller E,Sun M,Bartom ET,Maienschein-Cline M,Sigvardsson M,Kee BL
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Mon Jun 07 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
The Effect of miR-520b on Macrophage Polarization and T Cell Immunity by Targeting PTEN in Breast Cancer.
Journal of oncology
Zhu Q,Yuan J,He Y,Hu Y
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Immunohistochemistry
Wed Apr 27 00:00:00 EDT 2022
Exosomal lncRNA SNHG10 derived from colorectal cancer cells suppresses natural killer cell cytotoxicity by upregulating INHBC.
Cancer cell international
Huang Y,Luo Y,Ou W,Wang Y,Dong D,Peng X,Luo Y
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Expression of CCRL2 Inhibits Tumor Growth by Concentrating Chemerin and Inhibiting Neoangiogenesis.
Cancers
Al Delbany D,Robert V,Dubois-Vedrenne I,Del Prete A,Vernimmen M,Radi A,Lefort A,Libert F,Wittamer V,Sozzani S,Parmentier M
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Tue Oct 05 00:00:00 EDT 2021
Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials.
EBioMedicine
Okada R,Furusawa A,Vermeer DW,Inagaki F,Wakiyama H,Kato T,Nagaya T,Choyke PL,Spanos WC,Allen CT,Kobayashi H
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
A novel miR1983-TLR7-IFNβ circuit licenses NK cells to kill glioma cells, and is under the control of galectin-1.
Oncoimmunology
Shah D,Comba A,Faisal SM,Kadiyala P,Baker GJ,Alghamri MS,Doherty R,Zamler D,Nuñez G,Castro MG,Lowenstein PR
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation.
eLife
Wilfahrt D,Philips RL,Lama J,Kizerwetter M,Shapiro MJ,McCue SA,Kennedy MM,Rajcula MJ,Zeng H,Shapiro VS
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Protein Assays and Analysis
Thu Dec 02 00:00:00 EST 2021
Sequencing, cloning, and antigen binding analysis of monoclonal antibodies isolated from single mouse B cells.
STAR protocols
Viant C,Escolano A,Chen ST,Nussenzweig MC
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Fri Jun 18 00:00:00 EDT 2021
The enrichment of neutrophil extracellular traps impair the placentas of systemic lupus erythematosus through accumulating decidual NK cells.
Scientific reports
Jiang M,Shen N,Zhou H,Wang Y,Lin S,Wu J,Di W
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Thu Mar 25 00:00:00 EDT 2021
TNF-α-induced alterations in stromal progenitors enhance leukemic stem cell growth via CXCR2 signaling.
Cell reports
Agarwal P,Li H,Choi K,Hueneman K,He J,Welner RS,Starczynowski DT,Bhatia R
13-5941-82 was used in Flow Cytometry to find that TNF-α-mediated alterations in CML BM stromal niches enhance support of LSC maintenance and growth via CXCL1-CXCR2 signaling and that CXCR2 inhibition effectively depletes CML LSCs.
Tue Jul 13 00:00:00 EDT 2021
The subunits of IL-12, originating from two distinct cells, can functionally synergize to protect against pathogen dissemination in vivo.
Cell reports
Gerber AN,Abdi K,Singh NJ
13-5941-82 was used in Flow cytometry/Cell sorting to suggest that early secretion of IL-12p40 monomers by sentinel cells at the infection site may help prepare distal host tissues for potential pathogen arrival.
Tue Oct 12 00:00:00 EDT 2021
Plasmacytoid Dendritic Cells and Type I Interferon Promote Extrafollicular B Cell Responses to Extracellular Self-DNA.
Immunity
Soni C,Perez OA,Voss WN,Pucella JN,Serpas L,Mehl J,Ching KL,Goike J,Georgiou G,Ippolito GC,Sisirak V,Reizis B
13-5941-82 was used in Flow Cytometry to establish extrafollicular B cell differentiation into short-lived AFCs as a key mechanism of anti-DNA autoreactivity and reveal a major contribution of pDCs, endosomal Toll-like receptors (TLRs), and IFN-I to this pathway.
Tue Jun 16 00:00:00 EDT 2020
Notch2 complements Notch1 to mediate inductive signaling that initiates early T cell development.
The Journal of cell biology
Romero-Wolf M,Shin B,Zhou W,Koizumi M,Rothenberg EV,Hosokawa H
13-5941 was used in Flow cytometry/Cell sorting to define a distinct mechanism of Notch signal response that distinguishes the initial stages of murine T cell development.
Mon Oct 05 00:00:00 EDT 2020
Critical role of WNK1 in MYC-dependent early mouse thymocyte development.
eLife
Köchl R,Vanes L,Llorian Sopena M,Chakravarty P,Hartweger H,Fountain K,White A,Cowan J,Anderson G,Tybulewicz VL
13-5941 was used in Flow cytometry/Cell sorting to ind that WNK1 is required for the transition of double negative (DN) thymocytes through the β-selection checkpoint and subsequent proliferation and differentiation into double positive (DP) thymocytes.
Wed Oct 14 00:00:00 EDT 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Fri Jun 19 00:00:00 EDT 2020
Use of Busulfan to Condition Mice for Bone Marrow Transplantation.
STAR protocols
Montecino-Rodriguez E,Dorshkind K
13-5941 was used in Flow cytometry/Cell sorting to describe a protocol for the use of busulfan to condition mice for bone marrow transplantation and several of the variables to consider for effective implementation.
Fri Dec 18 00:00:00 EST 2020
Dendritic Cells and Myeloid Derived Suppressor Cells Fully Responsive to Stimulation via Toll-Like Receptor 4 Are Rapidly Induced from Bone-Marrow Cells by Granulocyte-Macrophage Colony-Stimulating Factor.
Vaccines
Kong YY,Wilson K,Apostolopoulos V,Plebanski M
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Sat Sep 12 00:00:00 EDT 2020
Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature
Escolano A,Gristick HB,Abernathy ME,Merkenschlager J,Gautam R,Oliveira TY,Pai J,West AP,Barnes CO,Cohen AA,Wang H,Golijanin J,Yost D,Keeffe JR,Wang Z,Zhao P,Yao KH,Bauer J,Nogueira L,Gao H,Voll AV,Montefiori DC,Seaman MS,Gazumyan A,Silva M,McGuire AT,Stamatatos L,Irvine DJ,Wells L,Martin MA,Bjorkman PJ,Nussenzweig MC
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Sat Jun 01 00:00:00 EDT 2019
Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells.
Cell stem cell
Agarwal P,Isringhausen S,Li H,Paterson AJ,He J,Gomariz Á,Nagasawa T,Nombela-Arrieta C,Bhatia R
13-5941-82 was used in Flow Cytometry to highlight a critical role of niche-specific effects of Cxcl12 expression in maintaining quiescence of TKI-resistant LSC populations.
Thu May 02 00:00:00 EDT 2019
SIRT1 regulates metabolism and leukemogenic potential in CML stem cells.
The Journal of clinical investigation
Abraham A,Qiu S,Chacko BK,Li H,Paterson A,He J,Agarwal P,Shah M,Welner R,Darley-Usmar VM,Bhatia R
13-5941 was used in Flow cytometry/Cell sorting to demonstrate an important role for SIRT1 in leukemia development.
Mon Jun 10 00:00:00 EDT 2019
Salmonella infection leads to severe intestinal inflammation and increased CD4+FoxP3+ Treg cells in streptozotocin‑induced hyperglycemic mice.
Molecular medicine reports
Zhang S,Wang M,Wang X,Li H,Tang H,Li X
13-5941-82 was used in Flow Cytometry to use streptozotocin‚induced hyperglycemic mice to model T1DM and induced a Salmonella infection in the mouse model, leading to aggravated inflammation, which resulted in an elevated proportion of CD103+CD11b+ DCs and a significantly elevated proportion of CD4+FoxP3+ Tregs in the intestinal lamina propria.
Sat Jun 01 00:00:00 EDT 2019
Synergized regulation of NK cell education by NKG2A and specific Ly49 family members.
Nature communications
Zhang X,Feng J,Chen S,Yang H,Dong Z
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2019
Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells.
JCI insight
Huang A,Shinde PV,Huang J,Senff T,Xu HC,Margotta C,Häussinger D,Willnow TE,Zhang J,Pandyra AA,Timm J,Weggen S,Lang KS,Lang PA
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Thu Sep 05 00:00:00 EDT 2019
Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia.
Nature communications
Hayashi Y,Goyama S,Liu X,Tamura M,Asada S,Tanaka Y,Fukuyama T,Wunderlich M,O'Brien E,Mizukawa B,Yamazaki S,Matsumoto A,Yamasaki S,Shibata T,Matsuda K,Sashida G,Takizawa H,Kitamura T
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Fri Oct 25 00:00:00 EDT 2019
Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death.
Nature communications
Sasaki K,Himeno A,Nakagawa T,Sasaki Y,Kiyonari H,Iwai K
13-5941-82 was used in Flow Cytometry to show that T cell-mediated killing and sequential autoinflammation are common and crucial for pathogenic diversity during T cell-mediated autoimmune responses.
Wed Aug 28 00:00:00 EDT 2019
Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia.
Nature medicine
Zhang B,Nguyen LXT,Li L,Zhao D,Kumar B,Wu H,Lin A,Pellicano F,Hopcroft L,Su YL,Copland M,Holyoake TL,Kuo CJ,Bhatia R,Snyder DS,Ali H,Stein AS,Brewer C,Wang H,McDonald T,Swiderski P,Troadec E,Chen CC,Dorrance A,Pullarkat V,Yuan YC,Perrotti D,Carlesso N,Forman SJ,Kortylewski M,Kuo YH,Marcucci G
13-5941 was used in Flow cytometry/Cell sorting to demonstrate how bone marrow endothelial cells supply miR-126 to leukemia stem cells in chronic myelogenous leukemia which modulates their quiescence and self-renewal.
Tue May 01 00:00:00 EDT 2018
CD8+ T cells mediate the antitumor activity of frankincense and myrrh in hepatocellular carcinoma.
Journal of translational medicine
Xu C,Lu X,Liu W,Chen A,Meng G,Zhang H,Li B,Zhang Y,Wu J,Wei J
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Mon May 21 00:00:00 EDT 2018
Plasmodium co-infection protects against chikungunya virus-induced pathologies.
Nature communications
Teo TH,Lum FM,Ghaffar K,Chan YH,Amrun SN,Tan JJL,Lee CYP,Chua TK,Carissimo G,Lee WWL,Claser C,Rajarethinam R,Rénia L,Ng LFP
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Tue Sep 25 00:00:00 EDT 2018
Hematopoietic stem cells can differentiate into restricted myeloid progenitors before cell division in mice.
Nature communications
Grinenko T,Eugster A,Thielecke L,Ramasz B,Krüger A,Dietz S,Glauche I,Gerbaulet A,von Bonin M,Basak O,Clevers H,Chavakis T,Wielockx B
13-5941-82 was used in Flow Cytometry to study the mechanisms that control fate decision in adult haematopoietic stem cells.s.
Tue May 15 00:00:00 EDT 2018
A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment.
eLife
Ng KK,Yui MA,Mehta A,Siu S,Irwin B,Pease S,Hirose S,Elowitz MB,Rothenberg EV,Kueh HY
13-5941-82 was used in Flow Cytometry to study the activation of Bcl11b, which controls T-cell fate commitment.
Tue Nov 20 00:00:00 EST 2018
Eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challenge.
Nature communications
Yi S,Zhai J,Niu R,Zhu G,Wang M,Liu J,Huang H,Wang Y,Jing X,Kang L,Song W,Shi Y,Tang H
Mon Sep 24 00:00:00 EDT 2018
A Viral Immunoevasin Controls Innate Immunity by Targeting the Prototypical Natural Killer Cell Receptor Family.
Cell
Aguilar OA,Berry R,Rahim MMA,Reichel JJ,Popović B,Tanaka M,Fu Z,Balaji GR,Lau TNH,Tu MM,Kirkham CL,Mahmoud AB,Mesci A,Krmpotić A,Allan DSJ,Makrigiannis AP,Jonjić S,Rossjohn J,Carlyle JR
13-5941 was used in Flow cytometry/Cell sorting to identify a viral ligand for the inhibitory and activating NKR-P1 receptors.
Thu Mar 23 00:00:00 EDT 2017
Differentiation of human and murine induced pluripotent stem cells to microglia-like cells.
Nature neuroscience
Pandya H,Shen MJ,Ichikawa DM,Sedlock AB,Choi Y,Johnson KR,Kim G,Brown MA,Elkahloun AG,Maric D,Sweeney CL,Gossa S,Malech HL,McGavern DB,Park JK
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells.
Leukemia
Cheadle EJ,Lipowska-Bhalla G,Dovedi SJ,Fagnano E,Klein C,Honeychurch J,Illidge TM
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Sat Jul 01 00:00:00 EDT 2017
Pre/pro-B cells generate macrophage populations during homeostasis and inflammation.
Proceedings of the National Academy of Sciences of the United States of America
Audzevich T,Bashford-Rogers R,Mabbott NA,Frampton D,Freeman TC,Potocnik A,Kellam P,Gilroy DW
13-5941 was used in Flow cytometry/Cell sorting to study the developmental plasticity of immature B cells and their role as the source of tissue resident macrophages.
Tue May 16 00:00:00 EDT 2017
mTORC2 regulates multiple aspects of NKT-cell development and function.
European journal of immunology
Sklarz T,Guan P,Gohil M,Cotton RM,Ge MQ,Haczku A,Das R,Jordan MS
13-5941 was used in Flow cytometry/Cell sorting to define the molecular pathway and role of Rictor in regulating invariant NKT-cell fate.
Wed Mar 01 00:00:00 EST 2017
IL-2/Anti-IL-2 Complex Attenuates Inflammation and BBB Disruption in Mice Subjected to Traumatic Brain Injury.
Frontiers in neurology
Gao W,Li F,Zhou Z,Xu X,Wu Y,Zhou S,Yin D,Sun D,Xiong J,Jiang R,Zhang J
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Loss of HIF-1α in natural killer cells inhibits tumour growth by stimulating non-productive angiogenesis.
Nature communications
Krzywinska E,Kantari-Mimoun C,Kerdiles Y,Sobecki M,Isagawa T,Gotthardt D,Castells M,Haubold J,Millien C,Viel T,Tavitian B,Takeda N,Fandrey J,Vivier E,Sexl V,Stockmann C
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Fri Nov 17 00:00:00 EST 2017
Acidic chitinase primes the protective immune response to gastrointestinal nematodes.
Nature immunology
Vannella KM,Ramalingam TR,Hart KM,de Queiroz Prado R,Sciurba J,Barron L,Borthwick LA,Smith AD,Mentink-Kane M,White S,Thompson RW,Cheever AW,Bock K,Moore I,Fitz LJ,Urban JF,Wynn TA
13-5941 was used in Flow cytometry/Cell sorting to use AMCase-deficient mice as a means to dissect the role of the enzyme in several models of helminth infection and type 2 cytokine-driven airway inflammation.
Sun May 01 00:00:00 EDT 2016
The breast tumor microenvironment alters the phenotype and function of natural killer cells.
Cellular & molecular immunology
Krneta T,Gillgrass A,Chew M,Ashkar AA
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Hypoxia-Inducible Factor-2α Limits Natural Killer T Cell Cytotoxicity in Renal Ischemia/Reperfusion Injury.
Journal of the American Society of Nephrology : JASN
Zhang J,Han C,Dai H,Hou J,Dong Y,Cui X,Xu L,Zhang M,Xia Q
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Nature communications
Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Wed Sep 07 00:00:00 EDT 2016
Restrained Th17 response and myeloid cell infiltration into the central nervous system by human decidua-derived mesenchymal stem cells during experimental autoimmune encephalomyelitis.
Stem cell research & therapy
Bravo B,Gallego MI,Flores AI,Bornstein R,Puente-Bedia A,Hernández J,de la Torre P,García-Zaragoza E,Perez-Tavarez R,Grande J,Ballester A,Ballester S
13-5941 was used in Flow cytometry/Cell sorting to explore the therapeutic potential of DMSCs for treatment of autoimmune disorders.
Thu Mar 17 00:00:00 EDT 2016
Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis.
Circulation research
Ye YX,Calcagno C,Binderup T,Courties G,Keliher EJ,Wojtkiewicz GR,Iwamoto Y,Tang J,Pérez-Medina C,Mani V,Ishino S,Johnbeck CB,Knigge U,Fayad ZA,Libby P,Weissleder R,Tawakol A,Dubey S,Belanger AP,Di Carli MF,Swirski FK,Kjaer A,Mulder WJ,Nahrendorf M
13-5941 was used in Flow cytometry/Cell sorting to perform (18)F-FLT positron emission tomography-computed tomography was performed in mice, rabbits, and humans with atherosclerosis.
Fri Oct 23 00:00:00 EDT 2015
Redundant Function of Plasmacytoid and Conventional Dendritic Cells Is Required To Survive a Natural Virus Infection.
Journal of virology
Kaminsky LW,Sei JJ,Parekh NJ,Davies ML,Reider IE,Krouse TE,Norbury CC
13-5941 was used in Flow cytometry/Cell sorting to explore the roles of individual myeloid cell subsets in the survival of ectromelia virus infection.
Thu Oct 01 00:00:00 EDT 2015
Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.
PloS one
Tähtinen S,Kaikkonen S,Merisalo-Soikkeli M,Grönberg-Vähä-Koskela S,Kanerva A,Parviainen S,Vähä-Koskela M,Hemminki A
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Thu Apr 28 00:00:00 EDT 2016
Metronomic cyclophosphamide eradicates large implanted GL261 gliomas by activating antitumor Cd8+ T-cell responses and immune memory.
Oncoimmunology
Wu J,Waxman DJ
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells.
Nature immunology
Mahmud SA,Manlove LS,Schmitz HM,Xing Y,Wang Y,Owen DL,Schenkel JM,Boomer JS,Green JM,Yagita H,Chi H,Hogquist KA,Farrar MA
13-5941 was used in Flow cytometry/Cell sorting to study the role of TNF receptors in the thymic development of Treg cells..
Thu May 01 00:00:00 EDT 2014
The Cebpa +37-kb enhancer directs transgene expression to myeloid progenitors and to long-term hematopoietic stem cells.
Journal of leukocyte biology
Guo H,Ma O,Friedman AD
13-5941 was used in Flow cytometry/Cell sorting to assess the selectiveness of the C/EBPα enhancer to regulate gene expression in particular cell types.
Mon Sep 01 00:00:00 EDT 2014
Specific microbiota-induced intestinal Th17 differentiation requires MHC class II but not GALT and mesenteric lymph nodes.
Journal of immunology (Baltimore, Md. : 1950)
Geem D,Medina-Contreras O,McBride M,Newberry RD,Koni PA,Denning TL
13-5941 was used in Magnetic cell separation to investigate whether GALT and/or mesenteric lymph nodes are required for intestinal Th17 differentiation, showing that specific microbiota-induced intestinal Th17 differentiation requires MHC class II.
Tue Jul 01 00:00:00 EDT 2014
Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface.
PloS one
Habbeddine M,Verbeke P,Karaz S,Bobé P,Kanellopoulos-Langevin C
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Wed Jun 10 00:00:00 EDT 2015
Thymus-autonomous T cell development in the absence of progenitor import.
The Journal of experimental medicine
Martins VC,Ruggiero E,Schlenner SM,Madan V,Schmidt M,Fink PJ,von Kalle C,Rodewald HR
13-5941 was used in Flow cytometry/Cell sorting to characterise the previously unrecognised capacity of the thymus to sustain T cell development during bone marrow progenitor deprivation.
Mon Jul 30 00:00:00 EDT 2012
Notch, Id2, and RORγt sequentially orchestrate the fetal development of lymphoid tissue inducer cells.
The Journal of experimental medicine
Cherrier M,Sawa S,Eberl G
13-5941 was used in Magnetic cell separation to investigate the development of lymphoid tissue inducer (LTi) cells from common lymphoid progenitors (CLPs) in the fetal liver, showing that sequential changes in expression of Notch, Id2, and RORγt orchestrate the development of LTi cells.
Mon Apr 09 00:00:00 EDT 2012
VEGF receptor inhibitors block the ability of metronomically dosed cyclophosphamide to activate innate immunity-induced tumor regression.
Cancer research
Doloff JC,Waxman DJ
Published figure using NK1.1 monoclonal antibody (Product # 13-5941-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2012
Immature murine NKT cells pass through a stage of developmentally programmed innate IL-4 secretion.
Journal of leukocyte biology
Dickgreber N,Farrand KJ,van Panhuys N,Knight DA,McKee SJ,Chong ML,Miranda-Hernandez S,Baxter AG,Locksley RM,Le Gros G,Hermans IF
13-5941 was used in Flow cytometry/Cell sorting to investigate the regulated pattern of IL-4 expression by maturing NKT cells, which may endow these cells with a capacity to influence the development of surrounding cells in the thymus.
Thu Nov 01 00:00:00 EDT 2012
Differential requirements for IRF-2 in generation of CD1d-independent T cells bearing NK cell receptors.
Journal of immunology (Baltimore, Md. : 1950)
Notake T,Horisawa S,Sanjo H,Miyagawa S,Hida S,Taki S
13-5941 was used in Flow cytometry/Cell sorting to investigate the mechanisms behind the generation and function of NKR(+) T cells.
Tue May 15 00:00:00 EDT 2012
Inflammatory spleen monocytes can upregulate CD11c expression without converting into dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Drutman SB,Kendall JC,Trombetta ES
13-5941 was used in Magnetic cell separation to establish the contribution of inflammatory DCs (iDCs) and conventional DCs (cDCs) in response to anti-CD40 administration in mice.
Sun Apr 15 00:00:00 EDT 2012
Protein kinase C-θ clustering at immunological synapses amplifies effector responses in NK cells.
Journal of immunology (Baltimore, Md. : 1950)
Merino E,Abeyweera TP,Firth MA,Zawislak CL,Basu R,Liu X,Sun JC,Huse M
13-5941 was used in Functional assays to study the role of compartmentalised PKC signalling in natural killer cell activation.
Thu Nov 15 00:00:00 EST 2012
Optimized protocol for the isolation of spleen-resident murine neutrophils.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Coquery CM,Loo W,Buszko M,Lannigan J,Erickson LD
13-5941 was used in Flow cytometry/Cell sorting to develop a protocol to optimally isolate spleen-resistant murine neutrophils.
Sat Sep 01 00:00:00 EDT 2012
Optimized protocol for the isolation of spleen-resident murine neutrophils.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Coquery CM,Loo W,Buszko M,Lannigan J,Erickson LD
13-5941 was used in Flow cytometry/Cell sorting to develop a protocol to optimally isolate spleen-resistant murine neutrophils.
Sat Sep 01 00:00:00 EDT 2012
Global transcriptional analysis of primitive thymocytes reveals accelerated dynamics of T cell specification in fetal stages.
Immunogenetics
Belyaev NN,Biró J,Athanasakis D,Fernandez-Reyes D,Potocnik AJ
13-5941 was used in Magnetic cell separation to compare the development of T cells in foetal and adult stages, showing that adult and foetal T cell progenitors.
Wed Aug 01 00:00:00 EDT 2012
Defective hematopoietic stem cell and lymphoid progenitor development in the Ts65Dn mouse model of Down syndrome: potential role of oxidative stress.
Antioxidants & redox signaling
Lorenzo LP,Chen H,Shatynski KE,Clark S,Yuan R,Harrison DE,Yarowsky PJ,Williams MS
13-5941 was used in Flow cytometry/Cell sorting to identify a link between oxidative stress and diminished IL-7Rα expression and function associated with defective haematologic development in a DS mouse model.
Sat Oct 15 00:00:00 EDT 2011
The central role of CD30L/CD30 interactions in allergic rhinitis pathogenesis in mice.
European journal of immunology
Fuchiwaki T,Sun X,Fujimura K,Yamada H,Shibata K,Muta H,Podack ER,Kawauchi H,Yoshikai Y
13-5941 was used in Flow cytometry/Cell sorting to examine the role of CD30 ligand in allergic rhinitis.
Sat Oct 01 00:00:00 EDT 2011
Growth factor independence 1 protects hematopoietic stem cells against apoptosis but also prevents the development of a myeloproliferative-like disease.
Stem cells (Dayton, Ohio)
Khandanpour C,Kosan C,Gaudreau MC,Dührsen U,Hébert J,Zeng H,Möröy T
13-5941 was used in Flow cytometry/Cell sorting to demonstrate that growth factor independence 1 protects against apoptosis in haematopoietic stem cells and prevents the development of myeloproliferative diseases.
Tue Feb 01 00:00:00 EST 2011
Hepatic stellate cells function as regulatory bystanders.
Journal of immunology (Baltimore, Md. : 1950)
Ichikawa S,Mucida D,Tyznik AJ,Kronenberg M,Cheroutre H
13-5941 was used in Magnetic cell separation to suggest that HSC can function as regulatory bystanders, and therefore, by promoting Tregs and suppressing Th17 differentiation, they might represent key players in the mechanism that drives liver-induced tolerance.
Sun May 15 00:00:00 EDT 2011
IL-1β and TNFα-initiated IL-6-STAT3 pathway is critical in mediating inflammatory cytokines and RANKL expression in inflammatory arthritis.
International immunology
Mori T,Miyamoto T,Yoshida H,Asakawa M,Kawasumi M,Kobayashi T,Morioka H,Chiba K,Toyama Y,Yoshimura A
13-5941 was used in Functional assays to elucidate the role of cytokines in chronic inflammation and joint destruction in rheumatoid arthritis.
Tue Nov 01 00:00:00 EDT 2011
Bioluminescent imaging reveals divergent viral pathogenesis in two strains of Stat1-deficient mice, and in αßγ interferon receptor-deficient mice.
PloS one
Pasieka TJ,Collins L,O'Connor MA,Chen Y,Parker ZM,Berwin BL,Piwnica-Worms DR,Leib DA
13-5941 was used in Flow cytometry/Cell sorting to examine HSV-1 pathogenesis in Stat1(-/-) mice and in IFNαβγR(-/-) mice, showing divergent viral pathogenesis between mouse strains.
Tue Feb 14 00:00:00 EST 2012
Online nanoflow multidimensional fractionation for high efficiency phosphopeptide analysis.
Molecular & cellular proteomics : MCP
Ficarro SB,Zhang Y,Carrasco-Alfonso MJ,Garg B,Adelmant G,Webber JT,Luckey CJ,Marto JA
13-5941 was used in Flow cytometry/Cell sorting to explore two novel multidimensional fractionation strategies for the gathering of phosphoproteomics data.
Tue Nov 01 00:00:00 EDT 2011
Wnt4 enhances murine hematopoietic progenitor cell expansion through a planar cell polarity-like pathway.
PloS one
Heinonen KM,Vanegas JR,Lew D,Krosl J,Perreault C
13-5941 was used in Flow cytometry/Cell sorting to establish a functional role for non-canonical Wnt signalling in hematopoiesis through a pathway involving Wnt4, Fz6, Rac1 and Jnk kinases.
Tue Apr 26 00:00:00 EDT 2011
Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths.
Immunity
Ohnmacht C,Schwartz C,Panzer M,Schiedewitz I,Naumann R,Voehringer D
13-5941 was used in Flow cytometry/Cell sorting to demonstrate that basophils play an important role for protective immunity against helminths and orchestrate chronic allergic inflammation.
Fri Sep 24 00:00:00 EDT 2010
Dendritic cells continue to capture and present antigens after maturation in vivo.
Journal of immunology (Baltimore, Md. : 1950)
Drutman SB,Trombetta ES
13-5941 was used in Magnetic cell separation to study the dynamics of Ag capture and presentation in situ, showing that dendritic cells continue to capture and present antigens after maturation.
Sun Aug 15 00:00:00 EDT 2010
Critical protective role for MCP-1 in pneumonic Burkholderia mallei infection.
Journal of immunology (Baltimore, Md. : 1950)
Goodyear A,Jones A,Troyer R,Bielefeldt-Ohmann H,Dow S
13-5941 was used in Flow cytometry/Cell sorting to assess the role of MCP-1 in immunity to acute pneumonia caused by gram-negative bacteria.
Mon Feb 01 00:00:00 EST 2010
Monocyte trafficking to hepatic sites of bacterial infection is chemokine independent and directed by focal intercellular adhesion molecule-1 expression.
Journal of immunology (Baltimore, Md. : 1950)
Shi C,Velázquez P,Hohl TM,Leiner I,Dustin ML,Pamer EG
13-5941 was used in Flow cytometry/Cell sorting to demonstrate that Ly6C(high) monocyte recruitment from the bloodstream to L. monocytogenes-infected liver is dependent on integrin and extracellular matrix-mediated monocyte adhesion.
Tue Jun 01 00:00:00 EDT 2010
Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappaB signals.
Nature immunology
Derudder E,Cadera EJ,Vahl JC,Wang J,Fox CJ,Zha S,van Loo G,Pasparakis M,Schlissel MS,Schmidt-Supprian M,Rajewsky K
13-5941 was used in Magnetic cell separation to define two distinct, consecutive phases of early B cell development that differ in their dependence on IKK-mediated NF-kappaB signaling.
Mon Jun 01 00:00:00 EDT 2009
Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity.
The Journal of experimental medicine
Ohnmacht C,Pullner A,King SB,Drexler I,Meier S,Brocker T,Voehringer D
13-5941 was used in Flow cytometry/Cell sorting to demonstrate that dendritic cells play an essential role to protect against fatal CD4+ T cell autoimmunity under steady-state conditions in addition to inducing tolerance.
Mon Mar 16 00:00:00 EDT 2009
Viral sequestration of antigen subverts cross presentation to CD8(+) T cells.
PLoS pathogens
Tewalt EF,Grant JM,Granger EL,Palmer DC,Heuss ND,Gregerson DS,Restifo NP,Norbury CC
13-5941 was used in Flow cytometry/Cell sorting to describe an evasion mechanism employed by pathogens to prevent entry into the cross-presentation pathway.
Fri May 01 00:00:00 EDT 2009
Dendritic cells are required for optimal activation of natural killer functions following primary infection with herpes simplex virus type 1.
Journal of virology
Kassim SH,Rajasagi NK,Ritz BW,Pruett SB,Gardner EM,Chervenak R,Jennings SR
13-5941 was used in Flow cytometry/Cell sorting to provide evidence that functional DCs are required for optimal IFN-gamma expression and cytolytic function by NK cells following HSV-1 infection.
Wed Apr 01 00:00:00 EDT 2009
Enhanced NK-cell development and function in BCAP-deficient mice.
Blood
MacFarlane AW,Yamazaki T,Fang M,Sigal LJ,Kurosaki T,Campbell KS
13-5941 was used in Functional assays to show that the B-cell adaptor for phosphatidylinositol 3-kinase is strongly expressed in natural killer cells and plays an important role in their development.
Tue Jul 01 00:00:00 EDT 2008
Enhanced NK-cell development and function in BCAP-deficient mice.
Blood
MacFarlane AW,Yamazaki T,Fang M,Sigal LJ,Kurosaki T,Campbell KS
13-5941 was used in Functional assays to show that the B-cell adaptor for phosphatidylinositol 3-kinase is strongly expressed in natural killer cells and plays an important role in their development.
Tue Jul 01 00:00:00 EDT 2008
E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors.
Journal of immunology (Baltimore, Md. : 1950)
Yang Q,Kardava L,St Leger A,Martincic K,Varnum-Finney B,Bernstein ID,Milcarek C,Borghesi L
13-5941 was used in Flow cytometry/Cell sorting to show E47 controls the developmental integrity and cell cycle quiescence of hematopoietic progenitors.
Sat Nov 01 00:00:00 EDT 2008
Runx proteins are involved in regulation of CD122, Ly49 family and IFN-gamma expression during NK cell differentiation.
International immunology
Ohno S,Sato T,Kohu K,Takeda K,Okumura K,Satake M,Habu S
13-5941 was used in Flow cytometry/Cell sorting to investigate the role of Runx family proteins in NK cells, showing that they are involved in regulation of CD122, Ly49 family and IFN-gamma expression during differentiation.
Tue Jan 01 00:00:00 EST 2008
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling.
Proceedings of the National Academy of Sciences of the United States of America
Tsuji M,Shinkura R,Kuroda K,Yabe D,Honjo T
13-5941-82 was used in Flow Cytometry to o investigate where and how Notch regulates early T cell differentiation by using specific up-regulation of Notch signaling by Mint knockout.
Tue Jan 30 00:00:00 EST 2007
Immature hematopoietic cells display selective requirements for adhesion- and degranulation-promoting adaptor protein in development and homeostatsis.
European journal of immunology
Dluzniewska J,Zou L,Harmon IR,Ellingson MT,Peterson EJ
13-5941-82 was used in Flow Cytometry to highlight the dynamic regulation of ADAP during T cell maturation and document expression patterns that suggest a possible role for ADAP in development of non-T hematopoietic lineages.
Thu Nov 01 00:00:00 EDT 2007
In vivo ablation of CD11c-positive dendritic cells increases susceptibility to herpes simplex virus type 1 infection and diminishes NK and T-cell responses.
Journal of virology
Kassim SH,Rajasagi NK,Zhao X,Chervenak R,Jennings SR
13-5941 was used in Flow cytometry/Cell sorting to investigate the role of different dendritic cell subsets in response to herpes simplex virus type 1 infection in mice.
Sat Apr 01 00:00:00 EST 2006
Basophils play a critical role in the development of IgE-mediated chronic allergic inflammation independently of T cells and mast cells.
Immunity
Mukai K,Matsuoka K,Taya C,Suzuki H,Yokozeki H,Nishioka K,Hirokawa K,Etori M,Yamashita M,Kubota T,Minegishi Y,Yonekawa H,Karasuyama H
13-5941 was used in Flow cytometry/Cell sorting to reveal a novel basophil-induced mechanism of development of chronic allergic inflammation.
Mon Aug 01 00:00:00 EDT 2005
