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Thermo Fisher Scientific offers an array of imaging reagents and kits to detect cells undergoing apoptosis. Select from a wide variety of caspase activity assays, DNA fragmentation and TUNEL assays, annexin V staining reagents and mitochondrial assays.
Many different approaches are used in the study of programmed cell death, or apoptosis. Cell death cascades are complex and dynamic, underscoring the importance of a multi-parametric approach for accurate assessment. Understanding the mechanisms of cell death and survival can represent a critical aspect of toxicological profiling and drug discovery. See our range of imaging assays to detect apoptotic cells undergoing processes ranging from caspase activation to phosphatidylserine translocation.
Annexin V staining is used to detect a hallmark of apoptosis, translocation of phosphatidylserine to the outer leaflet of the plasma membrane.
Activation of caspase enzymes is a distinctive feature of apoptosis.
DNA fragmentation and chromatin condensation are observed changes during apoptosis.
Disruption of mitochondria function is a distinguishing feature of apoptosis.
Apoptosis Pathways
Apoptosis is the tightly regulated process of controlled cell death in multicellular organisms. Learn more about several of the important pathways.
Apoptosis Information in Cell Analysis Learning Center
Access application notes, webinars and other useful educational resources to help you navigate the complex world of apoptosis research.
Cell Analysis Support Center
Find technical information, tips and tricks, and answers to everyday problems.
For Research Use Only. Not for use in diagnostic procedures.