mRNA Bioprocessing Solutions

Purpose-built to pioneer the single-use technology market by delivering a rigorous solution for microbial fermentation applications while offering the flexibility, ease of use, and efficiency found in single-use systems.

Chemically defined, animal origin free (AOF), dry powder medium designed to support high cell density cultures of Escherichia coli.

We offer an extensive portfolio of nutritionally diverse animal-origin (AO) and animal-origin-free (AOF) peptones for a variety of microbial cultures.

Gibco Water for Injection (WFI) for Cell Culture is high-quality water for use as a solvent in the preparation of cell culture media, laboratory reagents, buffers, and bioprocess liquids.

CentriPAK BioProcess Container chambers, manifold, labtainer (sterilized) with the connection. Designed for use in the Sorvall BIOS 16 Bioprocessing Centrifuge and 6 x 2,000 mL or 8 x 2,000 mL Swing Bucket Rotor.

The Sorvall BIOS 16 centrifuge is designed for high-quality harvesting, separation, and purification bioprocessing methods that require run-to-run reproducibility and traceability. With an enhanced capacity of up to 16 L of sample volume, a compact footprint, and innovative features to optimize operations, maximizing productivity and efficiency is simplified.

The imPULSE Single-Use Mixer (S.U.M.) can be utilized for many bioprocess mixing applications. The imPULSE design features include innovative disc mixing technology, configurable high-end controls, and monitors to fit specific process requirements. These features all enable uniform, superior mixing—scalable from 30 L to 5,000 L.

Our Process Liquid Preparation Services can help simplify your weigh-dispense-hydration (formulation) workflow for process liquid and buffer manufacturing by leveraging ready-to-hydrate (trusted-weight dry powders) and ready-to-use (pre-made liquids) chemicals.

The DynaChrom Single-Use Chromatography System offers a wide range of flow rates and process volumes, making it a highly versatile and efficient choice for customers working in pilot to scale-up operations.

Ideally suited for the purification of larger molecules such as plasmids, the POROS XQ resin is a next–generation, high-capacity, high-resolution, salt–tolerant, strong anion exchange resin that enables >140 mg/mL dynamic binding capacity in the presence of up to 6.6 mS/cm NaCl, while delivering exceptional separation performance.

The POROS HIC resin utilizes a novel coating procedure for functionalization with unique hydrophobic ligands, making it suitable for bind/elute and flow-through applications at lower salt concentrations and with higher binding capacity and resolution than classical HIC resins.

Gibco Process Liquids are designed to help streamline in-house hydration processes associated with buffer preparation and to alleviate storage challenges. These solutions are cGMP-manufactured, comply with multi-compendial specifications, and come in a variety of package sizes.

High-throughput, automated approaches offer the advantage of quickly processing many samples, with a high degree of reproducibility and is easily adaptable to a 96-well plate format.

The AccuSEQ Real-Time PCR Detection Software is designed to work with the 7500 Fast Real-Time PCR instrument and the SEQ family of analytical detection and quantitation assays. Security, audit, and signature capabilities help enable 21 CFR compliance.

The resDNASEQ system is a fully integrated assay leveraging real-time PCR technology for the quantitation of residual host cell DNA with a qualified DNA reference standard. This established GMP-compliant solution is widely adopted for routine use in major global biopharma companies.

Offering easy operation and rapid assembly with the highest standards of materials and surface finish, available in 1, 3, 7, and 15 L sizes.

The HyPerforma Rocker Bioreactor is controlled by a HyPerforma G3Lab Controller and TruBio software, and is compatible with a 10 L, 20 L, or 50 L Thermo Scientific Rock-it BioProcess Container (BPC), allowing from 5 L to 25 L of working volume.

This HyPerforma DynaDrive S.U.B. and its cube-shaped tank and stirred-tank design utilize a novel drive train with multiple impellers. The mixing capability of the bioreactor is superior, which enables optimal mixing in working volumes from 5 L to 50 L.

Providing easy process scale-up or scale-down and the configurability to modify control strategies along with your process.

POROS Oligo (dT)25 Affinity Resin selectively captures mRNA via the polyadenylated (polyA) tail using simple salt and water purification steps, contributing to its ideal use in the purification and isolation of mRNA from in vitro transcription (IVT) manufacturing processes.

A cost-effective docking station solution, consisting of a mixing station and a plastic support container that holds a BioProcess Container (BPC) or tank liners. Optional dollies are available to maneuver the support containers.

Gibco Process Liquids are designed to help streamline in-house hydration processes associated with buffer preparation and to alleviate storage challenges. These solutions are cGMP-manufactured, comply with multi-compendial specifications, and come in a variety of package sizes.

Designed to quantitate residual plasmid DNA with any common alleles of KanR genes in bioproduction.

The MicroSEQ Rapid Microbial Identification System is ideal for environmental monitoring, contamination investigation, root cause analysis, raw materials testing, and microbial identification.

Thermo Scientific Bioprocess Containers (BPCs) and transfer assemblies are ready-to-use, single-use flexible containment systems for critical sterile liquid handling applications in the biopharmaceutical industry. Available from 50 mL to 3,000 L volumes.

Designed for a range of upstream and downstream applications—media and buffer preparation to biomass re-suspension and lysis process.

Our access to a global network of suppliers ensures a comprehensive portfolio that covers all chemical categories across the bioprocessing workflow and addresses any needs specific to a project or product development.

Customizable and engineered-to-order, the Fill Finish Solution helps provide outstanding integrity assurance, excellent lead times, and a range of easy-to-use, single-use consumables for compounding, final filtration, and final fill applications to enable high product quality while optimizing your workflow.

The Labtainer Pro BPC is a versatile product for high-value liquid-handling applications. With design flexibility throughout the portfolio, you can trust our high-quality films to help eliminate leaks and provide reliable liquid containment solutions from 50 mL to 20 L.