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Dye-Labeled Phosphoramidites |
Dye-labeled phosphoramidites are intended for oligonucleotide synthesis designed for molecular assays, microscopy, and microarrays. A broad range of labeling options are available with coupling efficiency, emission, and absorption spectra comparable to other commercially available dyes.
These phosphoramidites may be used on automated DNA synthesizers following standard synthesis and deprotection procedures. Fluorescent tags can be incorporated at the 5′ end of an oligonucleotide.
Thermo Scientific DyLight (DY) fluorescent labels offer choices with spectrally distinct colors for oligonucleotide labeling with ß-cyanoethyl phosphoramidites (CEP). Oligo labeling with ß-cyanoethyl phosphoramidites (CEP). Available to use in research applications without the constraints of licensing and royalty fees.
DY547 CEP | DY647 CEP | DY677 CEP | |
---|---|---|---|
Cat. No. | SY6332 | SY6334 | SY6336 |
Formula | C38H54IN4O2P | C47H63N4O5PS | C55H67N4O5PS |
Molecular weight | 756.74 g/mol | 827.07 g/mol | 927.18 g/mol |
HPLC purity | ≥90% at 547 nm | ≥85% at 647 nm | ≥85% at 677 nm |
Identity | UV-Vis spectrum conforms to that of the authentic sample | ||
Shipping / storage condition | Dry ice / –20°C | ||
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Phosphoramidites with fluoresceine and its derivatives like 6-carboxyfluorescein (6-FAM), hexachlorofluorescein (HEX), tetrachlorofluorescein (TET) are also available to provide you with flexibility in oligo labeling.
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Fluorescein CEP | 6-FAM CEP | HEX CEP | TET CEP | ||
---|---|---|---|---|---|
Cat. No. | 27-1606 | 27-1608 | SY6342 | SY6341 | |
Chemical name | [(3′,6′-dipivaloylfluoresceinyl)-5,6-carboamidohexyl]-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | Fluorescein dipivalate phosphoramidite, 6-isomer | 6-(4,7,2′,4′,5′,7′-hexachloro-3′,6′-dipivaloylfluoresceinyl-6-carboxamido)-hexyl-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | 5′-tetrachloro-fluorescein phosphoramidite | |
Formula | C46H58N3O10P | C46H58N3O10P | C46H52N3O10Cl6P | C46H54N3O10Cl4P | |
Molecular weight | 843.95 g/mol | 843.94 g/mol | 1050.63 g/mol | 981.73 g/mol | |
CAS / PubChem# | N/A | 204697-37-0 / 58114954 | 1360547-55-2 | 877049-90-6 | |
HPLC purity | ≥90% | ≥90% | ≥95% | ≥95% | |
31P NMR purity | 85% | ≥95% (6-isomer) | N/A | N/A | |
Shipping / storage condition | Dry ice / –20°C | ||||
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For Research Use Only. Not for use in diagnostic procedures.