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Search Thermo Fisher Scientific
Reliable solutions for every stage of therapeutic antibody development
In your efforts to discover, synthesize, characterize, and optimize antibody candidates, you need reliability. When you’re ready to scale up your manufacturing, you need consistency. We offer reliable, consistent, and innovative solutions for every stage of therapeutic antibody development, to help you ensure the quality and safety of your biologics.
From protein expression systems and immunoassays to bioreactors and plastics, we provide high performing reagents and full-process universal equipment and consumables to effectively minimize cross-contamination and maintain environmental stability. To help you ensure that a recombinant antibody is safe, effective, and accepted by regulatory authorities, we’re here for you with outstanding QA/QC services.
View our comprehensive list of products, services, and technologies to support you at every step of the therapeutic antibody development process.
Research into the biology and progression of a disease allows the identification and validation of druggable disease targets and their suitability for targeting with monoclonal antibody therapies.
Quick links: Genetic analysis | Protein analysis | Cell-based analysis | Commercialization solutions | Resources
Highly potent and specific siRNAs covering human pre-defined gene families and pathways, including the druggable genome
96- or 384-well plate based pre-spotted with dried-down Applied Biosystems TaqMan Gene Expression Assays delivers results in only 30–45 min
Multiplex protein quantitation using the Luminex instrument platform, covering >300 cytokines, chemokines, growth factors, and other protein targets
Designed with features that support sustainability objectives without compromising performance
A rapid, long-read NGS tool for analyzing the immune repertoire to capture the diversity of T cell receptor (TCR) rearrangements.
Best-coverage assays to detect the highest number of transcript variants possible, with gold-standard specificity, sensitivity, and reproducibility.
Advanced gRNA designs for maximum efficiency without sacrificing specificity; arrayed libraries in flexible formats for a wide variety of assays.
Potent and specific siRNAs covering the druggable genome, with proprietary algorithm and chemical modifications.
From targeted gene expression analysis to whole-transcriptome sequencing, combine simple sample preparation and intuitive data analysis.
Understand the functions of individual proteins and their place in complex biological systems with state-of-the-art proteomics mass spectrometry.
Investigate protein and RNA biomarkers in key disease research areas from single-analyte analysis using ELISA formats to multiplex bead-based assays.
Characterize protein interactions through methods such as immunoprecipitation, yeast two-hybrid screening, phage display, and more.
Generate complete structural information, uncover how antibodies function in the body, and show how they bind to antigens.
Make your pH measurements of your buffers and reagents fast and reliable with an extensive range of meters, electrodes and accessories designed to work seamlessly together.
Understand the role of regulatory T cells with reagents for expansion, differentiation and functional studies, and cytokine profiling.
A broad range of cell function and behavior assays and reagents that can be used on multiple instrument platforms.
Closely mimic the in vivo state and generate more physiologically relevant data with complete cell culture systems for mAb discovery.
Simultaneously analyze multiple proteins, gene expression, and cell functions such as oxidation, viability, cell cycle, apoptosis, and proliferation.
Maximise sample protection and user safety, with an emphasis on containment, comfort and convenience, all day, every day.
Generate antibodies that bind to the target, then engineer to improve performance e.g., chimerization, humanization, manufacture of recombinant antibody fragments, bispecific antibodies, and antibody drug conjugates.
Reliable and cost-effective method for obtaining customized DNA constructs with 100% sequence accuracy.
Numerous options for synthesis platforms, purity levels, modifications, and formats to meet a variety of research needs.
Improve accuracy and precision with pipetting systems that incorporate years of experience and innovation for consistent, reproducible results.
Preparation of optimized synthetic, expression-ready genes for stable and increased protein expression or DNA immunization.
Rapidly produce high amounts of protein with integrated expression system solutions that give yield, speed, and cost benefits.
Peptides synthesized using the latest FMOC solid-phase technology, and purified using HPLC.
Immunization adjuvants are used to increase or stimulate immune response when mixed and injected with prepared immunogens.
Chemically defined, protein-free formulation designed for maximum performance.
High-density, serum-free suspension culture and specially designed transfection reagents for the highest yields possible in a transient system.
High-quality magnetic beads with increased surface area for panning saturated phage solutions during phage display.
Platforms and software for cutting-edge images and high content imaging data in no time; exceptional resolution with subcellular, automated detection.
You can achieve your goals faster, more reliably and with less effort, with our technology advancements in contamination control and uniform growth conditions.
Create proteins with characteristics you need for affinity maturation; significantly reduce screening efforts compared to conventional mutagenesis.
The evaluation of biological and molecular/structural characteristics during development and production. Multi-attribute methods based on a combination of peptide mapping and mass spectroscopy are increasingly being used.
A fast, laser-based, automated cellular imaging and analysis platform for quantitative microscopy and phenotypic screening.
High-performance, fully automated, inverted, multi-channel fluorescence and transmitted light imaging system.
Compact, benchtop cell analyser that can be configured with up to four spatially separated lasers to flexibly design, run, and analyse panels of up to 14 colors.
Deliver type 1 ultrapure water straight from your tap and benefit from easy-to-use configurations and lasting economy.
Matched antibody pairs, uncoated and coated-plate ELISA kits, and multiplexing assays for reliability and specificity during ligand binding studies.
Cell-based assays and reagents for key cellular processes, including apoptosis, cell proliferation, cell cycle and viability.
A range of products for imaging biological processes in live animals to understand cellular activity, effects of drugs, and disease progression.
Simultaneously analyze multiple proteins, gene expression, and cell functions such as oxidation, viability, cell cycle, apoptosis, and proliferation.
A new workflow solution to increase throughput, reproducibility, and speed through automated reagent dispensing into a wide selection of plate and volume ranges.
A broad range of protein or peptide quantitation assays for your sample type and application.
SEC HPLC columns for monoclonal antibody, aggregate, and fractions separation.
A unique combination of innovative technologies in a start-to-finish workflow that is designed to be fast, reliable, reproducible, and easy to use.
Obtain maximum insights on your most complex molecules and biological systems, from whole-proteome profiling and quantitation, structural characterization to multiplexed single-cell proteomics.
A range of buffers, ion exchange or hydrophobic interaction column chemistries, and UHPLC instrumentation to meet the needs for robust analysis of charge variants in monoclonal antibodies.
Production of antibodies for clinical trials may include the use of alternative expression systems, continuous biomanufacturing systems, and non-chromatographic separation formats.
We are committed to meeting your toughest challenges with high-performing Gibco products and services customized to your research and production needs.
Our proven, scalable technologies include bioprocessing equipment and automation, and flexible and rigid containment.
Take advantage of our fully validated cGMP media manufacturing services when you are ready for full-scale production.
Providing the most comprehensive range or customizable packaging solutions to protect your high-value liquids.
Integrated stable cell line development solutions to simplify your development workflow and accelerate your processes to commercial manufacture.
Optimize your media and processes for increased titers, quality, and manufacturability with our media development services.
Scalability from research to cGMP manufacturing with a comprehensive bioreactor portfolio.
You can achieve your goals faster, more reliably and with less effort, with our technology advancements in contamination control and uniform growth conditions.
Resins designed specifically for the purification of antibody fragments and novel antibody formats.
For large scale manufacturing of biopharmaceuticals, high-performance and high-throughout resins.
A suite of resins suitable for bind/elute and flow-through applications; purify a wide variety of biomolecules at low salt concentrations.
Complete solution for extraction and quantitation of DNA from biopharmaceutical purification sample matrices.
Help ensure early detection of mycoplasma contamination and same day actionable results, with a sensitive real-time PCR based mycoplasma detection assay.
Get accurate, rapid results from a system that is part of a total workflow solution and lessen your testing challenges in a GMP environment.
An immuno-PCR based quantitation platform for sensitive and robust protein quantitation with a wide dynamic range.
Rapid, accurate identification of thousands of bacterial and fungal species typically in under 5 hours.
Separate biological molecules and polymers according to size using either SDS-PAGE / SEC-HPLC / capillary electrophoresis (reduced & nonreduced).
A universal, magnetic bead–based sample preparation technology for efficient sample clean-up for reproducible contaminant and impurity testing.
Research into the biology and progression of a disease allows the identification and validation of druggable disease targets and their suitability for targeting with monoclonal antibody therapies.
Quick links: Genetic analysis | Protein analysis | Cell-based analysis | Commercialization solutions | Resources
Highly potent and specific siRNAs covering human pre-defined gene families and pathways, including the druggable genome
96- or 384-well plate based pre-spotted with dried-down Applied Biosystems TaqMan Gene Expression Assays delivers results in only 30–45 min
Multiplex protein quantitation using the Luminex instrument platform, covering >300 cytokines, chemokines, growth factors, and other protein targets
Designed with features that support sustainability objectives without compromising performance
A rapid, long-read NGS tool for analyzing the immune repertoire to capture the diversity of T cell receptor (TCR) rearrangements.
Best-coverage assays to detect the highest number of transcript variants possible, with gold-standard specificity, sensitivity, and reproducibility.
Advanced gRNA designs for maximum efficiency without sacrificing specificity; arrayed libraries in flexible formats for a wide variety of assays.
Potent and specific siRNAs covering the druggable genome, with proprietary algorithm and chemical modifications.
From targeted gene expression analysis to whole-transcriptome sequencing, combine simple sample preparation and intuitive data analysis.
Understand the functions of individual proteins and their place in complex biological systems with state-of-the-art proteomics mass spectrometry.
Investigate protein and RNA biomarkers in key disease research areas from single-analyte analysis using ELISA formats to multiplex bead-based assays.
Characterize protein interactions through methods such as immunoprecipitation, yeast two-hybrid screening, phage display, and more.
Generate complete structural information, uncover how antibodies function in the body, and show how they bind to antigens.
Make your pH measurements of your buffers and reagents fast and reliable with an extensive range of meters, electrodes and accessories designed to work seamlessly together.
Understand the role of regulatory T cells with reagents for expansion, differentiation and functional studies, and cytokine profiling.
A broad range of cell function and behavior assays and reagents that can be used on multiple instrument platforms.
Closely mimic the in vivo state and generate more physiologically relevant data with complete cell culture systems for mAb discovery.
Simultaneously analyze multiple proteins, gene expression, and cell functions such as oxidation, viability, cell cycle, apoptosis, and proliferation.
Maximise sample protection and user safety, with an emphasis on containment, comfort and convenience, all day, every day.
Generate antibodies that bind to the target, then engineer to improve performance e.g., chimerization, humanization, manufacture of recombinant antibody fragments, bispecific antibodies, and antibody drug conjugates.
Reliable and cost-effective method for obtaining customized DNA constructs with 100% sequence accuracy.
Numerous options for synthesis platforms, purity levels, modifications, and formats to meet a variety of research needs.
Improve accuracy and precision with pipetting systems that incorporate years of experience and innovation for consistent, reproducible results.
Preparation of optimized synthetic, expression-ready genes for stable and increased protein expression or DNA immunization.
Rapidly produce high amounts of protein with integrated expression system solutions that give yield, speed, and cost benefits.
Peptides synthesized using the latest FMOC solid-phase technology, and purified using HPLC.
Immunization adjuvants are used to increase or stimulate immune response when mixed and injected with prepared immunogens.
Chemically defined, protein-free formulation designed for maximum performance.
High-density, serum-free suspension culture and specially designed transfection reagents for the highest yields possible in a transient system.
High-quality magnetic beads with increased surface area for panning saturated phage solutions during phage display.
Platforms and software for cutting-edge images and high content imaging data in no time; exceptional resolution with subcellular, automated detection.
You can achieve your goals faster, more reliably and with less effort, with our technology advancements in contamination control and uniform growth conditions.
Create proteins with characteristics you need for affinity maturation; significantly reduce screening efforts compared to conventional mutagenesis.
The evaluation of biological and molecular/structural characteristics during development and production. Multi-attribute methods based on a combination of peptide mapping and mass spectroscopy are increasingly being used.
A fast, laser-based, automated cellular imaging and analysis platform for quantitative microscopy and phenotypic screening.
High-performance, fully automated, inverted, multi-channel fluorescence and transmitted light imaging system.
Compact, benchtop cell analyser that can be configured with up to four spatially separated lasers to flexibly design, run, and analyse panels of up to 14 colors.
Deliver type 1 ultrapure water straight from your tap and benefit from easy-to-use configurations and lasting economy.
Matched antibody pairs, uncoated and coated-plate ELISA kits, and multiplexing assays for reliability and specificity during ligand binding studies.
Cell-based assays and reagents for key cellular processes, including apoptosis, cell proliferation, cell cycle and viability.
A range of products for imaging biological processes in live animals to understand cellular activity, effects of drugs, and disease progression.
Simultaneously analyze multiple proteins, gene expression, and cell functions such as oxidation, viability, cell cycle, apoptosis, and proliferation.
A new workflow solution to increase throughput, reproducibility, and speed through automated reagent dispensing into a wide selection of plate and volume ranges.
A broad range of protein or peptide quantitation assays for your sample type and application.
SEC HPLC columns for monoclonal antibody, aggregate, and fractions separation.
A unique combination of innovative technologies in a start-to-finish workflow that is designed to be fast, reliable, reproducible, and easy to use.
Obtain maximum insights on your most complex molecules and biological systems, from whole-proteome profiling and quantitation, structural characterization to multiplexed single-cell proteomics.
A range of buffers, ion exchange or hydrophobic interaction column chemistries, and UHPLC instrumentation to meet the needs for robust analysis of charge variants in monoclonal antibodies.
Production of antibodies for clinical trials may include the use of alternative expression systems, continuous biomanufacturing systems, and non-chromatographic separation formats.
We are committed to meeting your toughest challenges with high-performing Gibco products and services customized to your research and production needs.
Our proven, scalable technologies include bioprocessing equipment and automation, and flexible and rigid containment.
Take advantage of our fully validated cGMP media manufacturing services when you are ready for full-scale production.
Providing the most comprehensive range or customizable packaging solutions to protect your high-value liquids.
Integrated stable cell line development solutions to simplify your development workflow and accelerate your processes to commercial manufacture.
Optimize your media and processes for increased titers, quality, and manufacturability with our media development services.
Scalability from research to cGMP manufacturing with a comprehensive bioreactor portfolio.
You can achieve your goals faster, more reliably and with less effort, with our technology advancements in contamination control and uniform growth conditions.
Resins designed specifically for the purification of antibody fragments and novel antibody formats.
For large scale manufacturing of biopharmaceuticals, high-performance and high-throughout resins.
A suite of resins suitable for bind/elute and flow-through applications; purify a wide variety of biomolecules at low salt concentrations.
Complete solution for extraction and quantitation of DNA from biopharmaceutical purification sample matrices.
Help ensure early detection of mycoplasma contamination and same day actionable results, with a sensitive real-time PCR based mycoplasma detection assay.
Get accurate, rapid results from a system that is part of a total workflow solution and lessen your testing challenges in a GMP environment.
An immuno-PCR based quantitation platform for sensitive and robust protein quantitation with a wide dynamic range.
Rapid, accurate identification of thousands of bacterial and fungal species typically in under 5 hours.
Separate biological molecules and polymers according to size using either SDS-PAGE / SEC-HPLC / capillary electrophoresis (reduced & nonreduced).
A universal, magnetic bead–based sample preparation technology for efficient sample clean-up for reproducible contaminant and impurity testing.
Simplify your new lab set-up. With Jump Start, we can help to design your lab with the products that will set you up for success, all with special discounts.
Simplify processes and enable discovery with our innovative laboratory equipment—the essential infrastructure of science.
Solutions for Biotech scale up to accommodate more samples, more data, and higher production.
Simplify processes and enable discovery with our innovative laboratory consumables—the essential infrastructure of science.
No capacity, time, or resources to handle a project in-house? Outsource it to us and our staff of experts will handle the project for you.
There’s no time for downtime in your lab, our services and support packages keep your lab up and running.
Customization, security of supply, quality, and expertise are values beyond the products and services when you partner with us.
Antibody engineering technologies are constantly advancing, enabling the development of therapeutics with higher affinities and specificities. Download our infographic to learn more about navigating challenges at each stage of mAb development.
Monoclonal antibody therapeutics have been rapidly increasing their market share over the last decade. Read our white paper to learn more about methods for screening target candidates, key assays for functional characterization, analytical methods for the molecular characterization, and much more.
There is a growing need to improve and expand the range of tools for studying therapeutic mAbs as interest in this field of research intensifies. Read more about the latest technologies available to help you study antibody internalization and trafficking.
Thermo Fisher Scientific offers reliable solutions that help you design, characterize, and optimize candidates and maximize yield while also ensuring consistency, quality, and safety as you move toward clinical trials. Learn more about our end-to-end solutions in therapeutic antibody development.
For Research Use Only. Not for use in diagnostic procedures.