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3D cell cultures have great potential in disease modeling, regenerative medicine, and other models. 3D cell cultures, including spheroid and organoid cultures, offer opportunities to better understand complex biology than 2D cell cultures can provide.
2D cell culture models grown from immortalized cell lines have served as a foundation for disease modeling and drug development for decades. These cell cultures are generally easy to grow and maintain but typically lack biological complexity and physiological relevance.
3D cell cultures are developed to imitate tissue-like or organ-like characteristics that better replicate the cellular environment in vivo than do 2D cell cultures. They exhibit gene and protein expression signatures close to those observed in vivo. 3D cell cultures, such as organoids and spheroids, are now utilized in neurobiology, stem cell research, regenerative medicine, and cancer biology.
While generating in vitro 3D cell cultures can be more challenging, once established they can offer key insights for translational research. With advanced tissue engineering approaches, there has been considerable progression from 2D to 3D cell cultures that is helping provide more physiological relevance to in vitro experiments.
Let’s face it, you are in a difficult position: being asked to transition your research to more physiologically relevant models, but the path to generating and interrogating 3D cell culture models is not always obvious. Our cell model services will help extend your capabilities by deploying our dedicated team of cell biology experts to your custom 3D cell model project. We are a team of experienced researchers with access to the latest tools from the brands you trust. We work closely with cell culture and analysis systems experts to help solve your most difficult research problems.
Options include:
We are now offering free e-Learns to share our expertise and assist with advancing your research. Follow the links below and start your free learning adventure in the basics of 3D cell culture and then progress to our neural organoid training course.
Getting started in 3D cell culture
Neural organoid generation from PSCs
We have simplified our portfolio to show you how our most popular products and services are used as single tools or integrated system solutions. Expedite your search for the right product with our One Cell Biology Portfolio Brochure
Learning Centers
Access cell culture, transfection, and cell analysis educational resources for better experiment planning and execution.
Cell culture and analysis support centers
Find technical support recommendations for your cell culture, transfection, and cell analysis workflows, including tips for experimental setup and in-depth troubleshooting help.
For Research Use Only. Not for use in diagnostic procedures.