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Understanding brain and neuro-functions
Studying the brain and neuro-functions requires the knowledge of a vast selection of experimental methods, from cell preparation to image acquisition and analysis. Thermo Scientific Amira Software supports you in the most frequently used image analysis techniques, such as filament tracing and editing, DTI analysis, brain perfusion analysis, and object tracking. Combining Amira Software's versatility with state-of-the-art 3D visualization and image processing enables you to create custom workflows that extract exactly the desired type of information from an image.
Imaging data
Processing
Visualization
Analysis
可靠
凭借功能 强大的 分割和 图像 处理能力 与工作流程以及与科学界和数千名研究人员超过 20 年 的合作， 现已证明，我们基于数字成像的工作流程为 生物医学和生命科学研究提供了 可靠解决方案。
定制
由于您的需求独一无二且不断变化，我们的软件解决方案非常灵活并且可以定制。借助我们的脚本编写界面（Python、TCL）、与 MATLAB 桥接以及编程 API，您可以扩展我们的软件解决方案并整合您自己的 IP（知识产权）。如果需要，我们的专业服务团队可以帮助设计符合您需求的独特解决方案。
Insight from your peers
Explore industry-leading insights and research that can support your lab workflow. Amira Software can empower your lab with a cutting-edge, comprehensive imaging data analysis toolbox.
Helping scientists answer questions that enable breakthrough discoveries in life sciences, materials science, and industry.
 | Correlative Microscopy: Using Amira Software to Understand the Spread of Cancer Read more |
 | Amira Software Accelerates Veterinary Research with 3D Visualization and Analysis Read more |
 | Molecular Clarity—Discovering What’s Possible with Cryo-Electron Tomography Read more |
 | Cryo-Electron Tomography and 3D Software Advances Coronavirus Research Read more |
Understanding the complexity of cancer with correlative light electron microscopy and Amira Software
Understanding the interconnectivity of the brain is essential for functional brain research. This allows researchers to better understand how different parts of the brain jointly orchestrate higher cognitive functions and motor skills.
With Amira Software, you are able to perform the entire DTI analysis workflow by first converting images into Talairach coordinates. You are then able to map multiple brain images onto a reference brain. Once the brain images are aligned, gradient images can be converted into a tensor field, and nerve fiber bundles can be tracked and visualized with our state-of-the-art visualization tools.
With Amira Software, you are able to trace, analyze, and quantify 3D images of filamentous structures such as neurons and blood vessels. Filamentous networks can be reconstructed, and measures such as length, thickness, orientation, ranks, etc., can be computed and visualized in compelling 3D renderings. Tracing can be performed automatically or interactively, depending on the application and needs.
Our template-matching algorithm allows automatic detection and tracing of fine filaments in noisy cryo-EM data. Amira Software also enables you to edit the resulting graphs to remove image features erroneously identified as a filament or to add missing parts of a network.
Brain perfusion studies help researchers and scientist to understand the impact of strokes or other brain tissue diseases such as Alzheimer and dementia. The exact location and duration of a stroke can determine functional impact of the event.
With Amira Software, you are able to analyze brain perfusion in perfusion-weighted MRI and CT images. This analysis includes computation of mean transit time (MTT), cerebral blood flow (CBF), and cerebral blood volume (CBV).
In vitro neuroscience research has grown considerably in neurodegenerative, neurogenesis, and neurotoxicology applications. Neurite outgrowth and synaptogenesis are the gold standards for evaluating health and functionality of neurons. However, even in vitro, identification of neuronal outgrowth morphology is difficult.
Researchers manually tracing neurites and synaptogenic spots face variability and non-scalability. Amira Software’s three-dimensional neuroscience abilities can accurately and efficiently quantify neuronal morphology in 3D models to facilitate the high-throughput demands of this research.
Understanding the interconnectivity of the brain is essential for functional brain research. This allows researchers to better understand how different parts of the brain jointly orchestrate higher cognitive functions and motor skills.
With Amira Software, you are able to perform the entire DTI analysis workflow by first converting images into Talairach coordinates. You are then able to map multiple brain images onto a reference brain. Once the brain images are aligned, gradient images can be converted into a tensor field, and nerve fiber bundles can be tracked and visualized with our state-of-the-art visualization tools.
With Amira Software, you are able to trace, analyze, and quantify 3D images of filamentous structures such as neurons and blood vessels. Filamentous networks can be reconstructed, and measures such as length, thickness, orientation, ranks, etc., can be computed and visualized in compelling 3D renderings. Tracing can be performed automatically or interactively, depending on the application and needs.
Our template-matching algorithm allows automatic detection and tracing of fine filaments in noisy cryo-EM data. Amira Software also enables you to edit the resulting graphs to remove image features erroneously identified as a filament or to add missing parts of a network.
Brain perfusion studies help researchers and scientist to understand the impact of strokes or other brain tissue diseases such as Alzheimer and dementia. The exact location and duration of a stroke can determine functional impact of the event.
With Amira Software, you are able to analyze brain perfusion in perfusion-weighted MRI and CT images. This analysis includes computation of mean transit time (MTT), cerebral blood flow (CBF), and cerebral blood volume (CBV).
In vitro neuroscience research has grown considerably in neurodegenerative, neurogenesis, and neurotoxicology applications. Neurite outgrowth and synaptogenesis are the gold standards for evaluating health and functionality of neurons. However, even in vitro, identification of neuronal outgrowth morphology is difficult.
Researchers manually tracing neurites and synaptogenic spots face variability and non-scalability. Amira Software’s three-dimensional neuroscience abilities can accurately and efficiently quantify neuronal morphology in 3D models to facilitate the high-throughput demands of this research.
入门培训
通过专门为 Amira、Avizo 和 PerGeos 软件新用户设计的入门培训，缩短学习曲线，使投资收益最大化。
课程包括一个讲座及互动提问环节。培训材料重点讲述 Amira、Avizo 和 PerGeos 软件的基本特点和功能。
高级培训
通过专为 Amira、Avizo 和 PerGeos 软件的现有用户设计的高级培训使投资收益最大化并缩短取得成果的时间。
课程包括一个讲座及互动提问环节。培训材料重点讲述 Amira、Avizo 和 PerGeos 软件的高级特点和功能。
定制开发
赛默飞世尔科技在 3D 和图像处理方面拥有超过 25 年的经验，向众多小型和大型机构交付了数百个定制项目，可根据您的特定需求为您提供量身定制的解决方案。
我们可以定制和扩展我们不同级别的软件解决方案。
Visualization of the results of a Diffusion Tensor Imaging study of the human head Courtesy of Prof. Dr. Alexander Brawanski, University Hospital of Regensburg1001.
Visualization of a brain of Mus musculus.
Fertilizers effects on neuronal outgrowth and synapse expression by IUF – Leibniz Research Institute for Environmental Medicine.
Analysis of the neurites of a neurospheroid. Data courtesy of Dr. Stefan Masjosthusmann, IUF – Leibniz Research Institute for Environmental Medicine.
Visualization of the results of a Diffusion Tensor Imaging study of the human head. Courtesy of Prof. Dr. Alexander Brawanski, University Hospital of Regensburg.
Volume rendering of cleared spinal cord as imaged with 2-photon microscopy. Data courtesy of Ali Ertürk, Max Planck Institute of Neurobiology.
Tube rendering of traced axons colorized according to axon thickness. Data courtesy of Ali Ertürk, Max Planck Institute of Neurobiology.
Paired Helical Filaments (PHF). Data courtesy of The Medical Research Council Laboratory of Molecular Biology. Fitzpatrick et al., 2017.Data courtesy of The Medical Research Council Laboratory of Molecular Biology. Fitzpatrick et al., 2017.
Visualization of the results of a Diffusion Tensor Imaging study of the human head Courtesy of Prof. Dr. Alexander Brawanski, University Hospital of Regensburg1001.
Visualization of a brain of Mus musculus.
Fertilizers effects on neuronal outgrowth and synapse expression by IUF – Leibniz Research Institute for Environmental Medicine.
Analysis of the neurites of a neurospheroid. Data courtesy of Dr. Stefan Masjosthusmann, IUF – Leibniz Research Institute for Environmental Medicine.
Visualization of the results of a Diffusion Tensor Imaging study of the human head. Courtesy of Prof. Dr. Alexander Brawanski, University Hospital of Regensburg.
Volume rendering of cleared spinal cord as imaged with 2-photon microscopy. Data courtesy of Ali Ertürk, Max Planck Institute of Neurobiology.
Tube rendering of traced axons colorized according to axon thickness. Data courtesy of Ali Ertürk, Max Planck Institute of Neurobiology.
Paired Helical Filaments (PHF). Data courtesy of The Medical Research Council Laboratory of Molecular Biology. Fitzpatrick et al., 2017.Data courtesy of The Medical Research Council Laboratory of Molecular Biology. Fitzpatrick et al., 2017.
导入和处理您的成像数据
- 处理任何规模、任何大小及任何模态的数据：
- 生物数据格式
- 位图格式
- 显微镜：电子和光学
- 医学和神经图像格式
- 分子格式
- 其他图像采集设备（MRI、放射摄影术等）
- 有限元建模、几何建模、CAD
- 支持多数据/多视图、多通道、时间序列、超大数据
- 缩放、校准、转换、重新采样
- 图像增强、能满足各种需求的滤波和卷积、傅立叶变换
- 伪影消除算法
- 先进的多模式 2D/3D 自动配准
- 图像对齐、算术运算、相关、融合
轻松分割成像数据
- 阈值和自动分割、对象分离、自动标记
- 区域生长、活动轮廓、插值、卷绕、平滑
- 形态学处理，包括分水岭和盆地
- 基于机器学习的分割
- 自动追踪单个纤维和丝状体
- 骨架化和纤丝网络提取
- 交互式工具，用于生成或编辑分割和空间图形
- 3D 表面重建
- FEA/CFD 载网生成
导出您的分析和可视化工作以便无缝发布并演示
- 动画和视频生成
- 高级关键帧和物体动画
- 混合图像、几何模型、测量和模拟
- 注释、测量图例、柱状图和曲线图
- 导出电子表格、3D 模型和高质量图像
- 主动和被动 3D 立体视觉
- 单屏和多屏显示
- 沉浸式环境
For Research Use Only. Not for use in diagnostic procedures.
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