One Lambda Devyser Chimerism for NGS

Join the next generation of chimerism testing with the One Lambda Devyser Chimerism NGS Assay offers a high-throughput, sensitive solution for the detection of chimerism and microchimerism. 


Key features and benefits

  • Comprehensive coverage: Utilizes 24 indel markers to detect microchimerism in post-hematopoietic stem cell transplantation (HSCT) samples
  • Confidence in results: Achieves results with sensitivity down to >0.05%
  • Efficient workflow: Utilize a single universal mix and one workflow, reducing hands-on time in as little as 45 minutes, and delivers next-day sequencing results
  • Simplified analysis: User-friendly software simplifies chimerism assessment, enables flexible data presentation, and provides longitudinal tracking, all within one dedicated software
  • Professional support: Our dedicated team of scientists and specialists are available to answer your questions and guide you towards optimal use of One Lambda Devyser NGS Assay

What is the One Lambda Devyser Chimerism NGS Assay?

The next generation of chimerism testing

Designed to provide accurate and sensitive detection of microchimerism levels in samples, the One Lambda Devyser Chimerism NGS Assay is an excellent solution for HLA and molecular core labs. It offers a fast and repeatable workflow from sample to report and a unified workflow. One tube per sample avoids any need for sample splitting, and the single measurement method is independent of mixed chimerism levels. Leveraging next-generation sequencing (NGS) technology, our assay offers an unparalleled limit of detection of 0.05%, enabling the identification of even the smallest changes in chimerism status.

 

Fig. 1. Measured vs theoretical target chimerism %.

How does One Lambda Devyser Chimerism Assay work?

Easy workflow for maximum efficiency

Our One Lambda Devyser Chimerism NGS Assay offers an easy workflow that requires as little as 45 minutes of hands-on time, delivers results within 24 hours, and helps ensure maximum efficiency in your laboratory. By utilizing a single protocol, you can eliminate the need for sample-specific primers and marker tracking. The universal reagent mix allows for cost-effective testing, reducing reagent wastage and the need to keep multiple reagents in stock.

 

Highly accurate results with exceptional sensitivity

The One Lambda Devyser Chimerism NGS Assay combines the sensitivity of real-time PCR analysis and the precision of STR based analysis. The unique 24-indel panel allows for accurate detection of microchimerism, irrespective of mixed chimerism levels. With one tube per sample, there's no need for sample splitting, ensuring optimal sample integrity and reliable results.

 

Fig. 2. Genetic markers distributed over 17 chromosomes.

Dedicated software for fast and accurate result analysis

You can easily assess chimerism, sample type, and longitudinal tracking with the One Lambda Devyser Chimerism NGS Assay and its dedicated software. The dedicated data analysis software delivers precise and speedy chimerism status information. The user-friendly interface and flexible data display simplify data interpretation. With this comprehensive sample-to-result solution, you can optimize your lab resources while providing top-quality results. 

Fig. 3. User interface example.

Download Advyser Chimerism Software

Advyser Chimerism transforms chimerism analysis, offering a seamless, secure, and easy-to-use experience. With its easy integration, robust security, and a focus on user experience, Advyser Chimerism is the ideal software solution for laboratories committed to providing the highest standard of care in chimerism monitoring.

Take control of molecular research with Devyser Chimerism NGS Assay and Advyser Software

 

For Research Use Only. Not for use in diagnostic procedures. Availability of product in each country depends on local regulatory marketing authorization status.