Chromatography and Mass Spectrometry Instruments for Clinical Research and Toxicology Applications

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CategoryTitleAnalyteInstrument
Clinical researchStreamlined workflow for absolute quantitation of therapeutic monoclonal antibodies using Promise Proteomics mAbXmise kits and a TSQ Altis Plus mass spectrometerMonoclonal AntibodiesTriple Quadrupole
Clinical researchQuantification of Antiepileptics in Human Plasma or Serum by LC-HRAM(MS) for Clinical ResearchAntiepilepticsHRAM MS
Clinical researchQuantification of Tricyclic Antidepressants in Human Plasma or Serum by Liquid Chromatography-Tandem Mass Spectrometry for Clinical ResearchAntidepressantsTriple Quadrupole
Clinical researchQuantification of Antiepileptics in Human Plasma or Serum by Liquid Chromatography-Tandem Mass Spectrometry for Clinical ResearchAntiepilepticsTriple Quadrupole
Clinical researchQuantification of Antidepressants in Human Plasma or Serum by Liquid Chromatography-Tandem Mass Spectrometry for Clinical ResearchAntidepressantsTriple Quadrupole
Clinical researchQuantification of Antimycotics in Human Plasma or Serum by Liquid Chromatography-Tandem Mass Spectrometry for Clinical ResearchAntimycoticsTriple Quadrupole
Clinical researchQuantification of Mycophenolic Acid in Human Plasma by Liquid Chromatography-Tandem Mass Spectrometry for Clinical ResearchMycophenolic AcidTriple Quadrupole
Clinical researchQuantification of Thirty-One Antidepressants in Human Serum by Turboflow Chromatography Coupled to High-Resolution Orbitrap Mass Spectrometry for Clinical ResearchAntidepressantsHRAM MS
Clinical researchAnalytical Evaluation for the Quantitation of Fifteen Antibiotics in Plasma by Liquid Chromatography Coupled to High-Resolution, Accurate-Mass Measurements for Clinical ResearchAntibioticsHRAM MS
Clinical researchQuantitative Analysis of Antifungal Drugs using PaperSpray Tandem Mass for Clinical ResearchAntifungalsTriple Quadrupole / Paper Spray
Clinical researchQuantification of nine antimycotic drugs in human plasma or serum by LC-HRAM(MS) for clinical researchAntimycoticsHRAM MS
Clinical researchRobust, Reproducible, and Easy-to-Implement Plasma Protein Profiling Workflow using High-Flow UHPLC/MS/MS Without DepletionPlasma ProteomeHRAM MS
Clinical researchQuantification of Mycophenolic Acid in Human Plasma by LC-HRAM Mass Spectrometry for Clinical ResearchMycophenolic AcidHRAM MS
Clinical researchQuantification of 25-Hydroxyvitamin D2 and D3 in Human Plasma by LC-HRAM-MS for Clinical ResearchVitamin DHRAM MS
Clinical researchQuantification of 15 Tricyclic Antidepressants in Human Plasma by Liquid Chromatography-Tandem Mass Spectrometry for Clinical ResearchAntidepressantsTriple Quadrupole
Clinical researchQuantification of Eight Antimycotics in Human Plasma by Liquid Chromatography-Tandem Mass Spectrometry for Clinical ResearchAntimycoticsTriple Quadrupole
ToxicologyQuantitation of 22 fentanyl analog compounds with a TSQ Altis MD mass spectrometerDrugs of AbuseTriple Quadrupole
ToxicologySimultaneous quantitation of 77 therapeutic and clinical toxicology drugs in dried blood spots using the fully automated Transcend DSX-1 systemTherapeutic, Drugs of AbuseHRAM MS
ToxicologyDetection of Controlled Substances in Blood Samples using the Verispray Ion Source with TSQ Altis MS for Clinical Research and Forensic ToxicologyDrugs of AbuseTriple Quadrupole / Verispray
ToxicologyQuantification of 78 Drugs of Abuse in Human Blood by Liquid chromatography – HRAM Orbitrap Mass Spectrometry for Clinical ResearchDrugs of AbuseHRAM MS
ToxicologyImproving Limit of Quantification in Clinical Research by Combining Paperspray with FAIMS TechnologyAmitriptylineTriple Quadrupole
ToxicologyQuantification of Benzodiazepines in Human Plasma or Serum by Liquid Chromatography Tandem Mass Spectrometry for Clinical ResearchBenzodiazepinesTriple Quadrupole
ToxicologyTomorrow’s Quantitation with LC-MS/MS: Fast Screening and Quantitation of Drugs of Abuse in Urine for Forensic ToxicologyDrugs of AbuseTriple Quadrupole
ToxicologyForensic Toxicology Quantitation of 30 Benzodiazepines in Whole Blood using a High-Resolution, Accurate-Mass (HRAM) Mass SpectrometerBenzodiazepinesHRAM MS
ToxicologyDetermination of Cannabinoids in Low-Volume Human Whole Blood Samples by Online Extraction using Turbulent Flow Chromatography and HRAM Orbitrap MSCannabinoidsHRAM MS
ToxicologyTargeted Forensic Screening and Semi-Quantitation of Drugs in Plasma using High-Resolution, Accurate Mass Detection and Online Sample PreparationDrugs of AbuseHRAM MS
ToxicologyQuantification of 36 benzodiazepines in human plasma or serum by LC-HRAM(MS) for clinical researchBenzodiazepinesHRAM MS
ToxicologyQuantification of methylmalonic acid in human plasma or serum for use in clinical researchMethylmalonic acidTriple Quadrupole
ToxicologyQuantification of Ethyl Glucuronide and Ethyl Sulfate in Human Urine by LC-HRAM(MS) for Clinical ResearchEtG, EtSHRAM MS
ToxicologyQuantification of Phosphatidylethanol (PEth) 16:0/18:1 in Whole Blood with High-Resolution Accurate Mass Spectrometry for Clinical ResearchPethHRAM MS
ToxicologyQuantitation of 22 fentanyl analog compounds on an Orbitrap Exploris 120 mass spectrometerFentanylsHRAM MS
ToxicologyScreening and Semi-Quantitation of 212 Fentanyl Analog Compounds by the Orbitrap Exploris 120 Mass SpectrometerFentanylHRAM MS
ToxicologyQuantification of Eight Antimycotics in Human Plasma by LC-HRAM-MS for Clinical ResearchAntimycoticsHRAM MS
ToxicologyQuantification of 34 Benzodiazepines in Human Plasma by LC-HRAM-MS for Clinical ResearchBenzodiazepinesHRAM MS
BiomarkersFast and accurate quantitation of intact IGF-1 from serum by HRAM LC-MS for clinical researchIGF-1HRAM MS
BiomarkersQuantification of Insulin-Like Growth Factor 1 in Human Serum by Vanquish UHPLC with Q Exactive High-Resolution Accurate-Mass Mass Spectrometry for Clinical ResearchIGF-1HRAM MS
EndocrinologyQuantification of 25-Hydroxyvitamin D2 and D3 in Human Plasma by Liquid Chromatography-Tandem Mass Spectrometry for Clinical ResearchVitamin DTriple Quadrupole
EndocrinologyConfident Quantitation of 25-Hydroxyvitamin D2 and D3 in Human Plasma for Clinical Research by Liquid Chromatography-Tandem Mass Spectrometry with Simple, Robust Sample PreparationVitamin DTriple Quadrupole
EndocrinologyAchieving High Sensitivity and Robustness – Analysis of Estrone and Estradiol in Human Serum by Tsq Altis Mass Spectrometer for Clinical ResearchEstrone/EstradiolTriple Quadrupole
EndocrinologyQuantification of 25-Hydroxyvitamin D2 and D3 in Human Plasma by Liquid Chromatography Coupled to High-Resolution Orbitrap Mass Spectrometry for Clinical ResearchVitamin DTriple Quadrupole
EndocrinologyQuantitation of 25-OH Vit D in human plasma and serum for clinical research by LC-MS/MSVitamin DTriple Quadrupole
EndocrinologyConfident Quantification of Steroids: Analysis in Human Plasma or Serum by Liquid Chromatography Tandem Mass Spectrometry for Clinical ResearchSteroidsTriple Quadrupole
EndocrinologyQuantitative Analysis of Estradiol and Testosterone in Plasma for Clinical Research using the TSQ Altis Triple Quadrupole Mass SpectrometerEstradiol/TestosteroneTriple Quadrupole
EndocrinologyCortisol and cortisone in human urine by LC-MS: Quantification by high-resolution Orbitrap mass spectrometryCortisol/CortisoneHRAM MS
EndocrinologyQuantification of six steroids in human serum by TurboFlow chromatography coupled to tandem mass spectrometrySteroidsTriple Quadrupole
EndocrinologyBlood serum rT3 quantitation by LC-MS/MS: Using liquid-liquid extraction following protein precipitation for researchrT3Triple Quadrupole
EndocrinologyQuantification of vitamins B1, B2, and B6 in human blood by liquid chromatography-tandem mass spectrometry for clinical researchVitamin BTriple Quadrupole
Therapeutic drug monitoringCombined Paperspray and FAIMS Technology for Rapid Quantification of Immunosuppressants in Whole Blood for Clinical ResearchImmunosuppressantsTriple Quadrupole / Verispray / FAIMS
Therapeutic drug monitoringTomorrow’s Quantitation: Increased Robustness for Quantitation of Immunosuppressant Drugs in Blood with the TSQ Fortis MS for Clinical ResearchImmunosuppressantsTriple Quadrupole
Therapeutic drug monitoringQuantification of Immunosuppressants in Human Blood by Liquid Chromatography-Tandem Mass Spectrometry for Clinical ResearchImmunosuppressantsTriple Quadrupole
Therapeutic drug monitoringTesting Robustness: Immunosuppressant Drugs in Blood with a TSQ Quantis MS for Clinical ResearchImmunosuppressantsTriple Quadrupole
Therapeutic drug monitoringConfident quantification of immunosuppressants in human whole blood by LC-MS for clinical researchImmunosuppressantsTriple Quadrupole
Therapeutic drug monitoringFast and robust quantification of 36 antidepressants in human plasma by LC-HRAM(MS) using the Orbitrap Exploris 120 mass spectrometer for clinical researchAntidepressantsHRAM MS
Therapeutic drug monitoringQuantification of immunosuppressants in human blood by LC-HRAM mass spectrometry for clinical researchImmunosuppressantsHRAM MS
Disease & disordersQuantification of free metanephrines in human plasma by LC-MS/MS for clinical research Triple Quadrupole
Disease & disordersQuantification of Total Homocysteine in Human Plasma or Serum by Liquid Chromatography-Tandem Mass Spectrometry for use in Clinical Research Triple Quadrupole
Disease & disordersRobust, Reliable Assay to Quantify Total Homocysteine in Human Plasma or Serum by Liquid Chromatography Tandem Mass Spectrometry for use in Clinical Research Triple Quadrupole
Disease & disordersDetermination of inborn errors of metabolism: Quantification of amino acids and acylcarnitines in dried blood spots Triple Quadrupole
Disease & disordersQuantification of amino acids and acylcarnitines in dried blood spots by FIA-MS/MS Triple Quadrupole
Disease & disordersComparison of three automated data processing and reporting approaches for inborn errors of metabolism by LC-MS FIA Triple Quadrupole
Disease & disordersSimultaneous Analysis of Amino Acids, Acylcarnitines, and Succinylacetone in Dried Blood Spots for Research using Nonderivatized and Derivatized Methods Triple Quadrupole
Disease & disordersLC-MS for detection of SARS-CoV-2 viral and host proteins Triple Quadrupole / HRAM MS
Disease & disordersA quick and robust mass spectrometry-based method for the detection of SARS-CoV-2SARS-CoV-2 InstrumentTriple Quadrupole
Clinical ResearchQuantification of Eight Antimycotics in Human Plasma using an Orbitrap Exploris 120AntimycoticsHRAM MS
Disease & disorders  Quantification of Free Metanephrines in Human Plasma by LC-HRAM Mass Spectrometry for Clinical ResearchMetanephrinesHRAM MS
Disease & disorders  Quantification of Mycophenolic Acid in Human Plasma using an Orbitrap Exploris 120Mycophenolic acidHRAM MS
Clinical researchFast and Robust Quantification of 15 Tricyclic Antidepressants in Human Plasma by LC-HRAM(MS)AntidepressantsHRAM MS
Clinical researchQuantification of Total Homocysteine in Human Plasma or Serum by LC-HRAM-MS for Clinical ResearchAntidepressantsLC-HRAM-MS
Therapeutic drug monitoringQuantification of 28 Neuroleptics in Human Plasma by LC-HRAM-MS for Clinical ResearchAntipsychoticsHRAM MS
Therapeutic drug monitoringQuantification of Free Metanephrines in Human Plasma by LC-HRAM Mass Spectrometry for Clinical ResearchAntipsychoticsHRAM MS
ToxicologyQuantification of 35 Benzodiazepines in Human Plasma by LC-HRAM-MS for Clinical ResearchBenzodiazepines InstrumentHRAM MS
Therapeutic Drug MonitoringQuantification of Four Immunosuppressants in Human Blood by LC-HRAM-MS for Clinical ResearchImmunosuppressantsHRAM MS
Therapeutic Drug MonitoringQuantification of 36 Antidepressants in Human Plasma by LC-HRAM-MS for Clinical ResearchAntidepressants InstrumentHRAM MS
Clinical ResearchQuantification of 27 Antiepileptics in Human Plasma by LC-HRAM-MS for Clinical ResearchAntiepileptics InstrumentHRAM MS
Therapeutic drug monitoringQuantification of 28 Neuroleptics in Human Plasma by LC-HRAM-MS for Clinical ResearchAntipsychoticsHRAM MS
ToxicologyFully Automated Dried Spot Analysis for the Rapid Quantitation of Tramadol and its Metabolites in Various MatricesTramadolTriple Quadrupole
Clinical ResearchQuantitative analysis of 28 trace elements in human plasma and serum by triple quadrupole inductively coupled plasmaTrace ElementsTriple Quadrupole / ICP-MS
ToxicologyDirect quantitation of phosphatidylethanol (PEth) in volume-controlled dried whole blood spots using the fully automated Transcend DSX-1 systemPEthTriple Quadrupole
ToxicologyHRAM screening, quantitation, and confirmation of drugs with Tox Explorer Orbitrap Exploris platformDrugs of AbuseHRAM MS
ToxicologyAll-in-one LC-MS/MS toxicology solution for drugs of abuse quantitation using the TSQ Quantis Plus mass spectrometerDrugs of AbuseTriple quadrupole
ToxicologyQuantitative analysis of cannabinoids in urine and oral fluid using reactive paper spray tandem mass spectrometry for clinical research and forensic toxicologyCannabinoidsTriple Quadrupole/Verispray
Clinical ResearchMonitoring the intact light chain of therapeutic monoclonal antibodies in human serum using an Orbitrap Exploris 240 mass spectrometer for clinical researchMonoclonal AntibodiesHRAM
Diseases and disordersA reliable and simple FIA-MS/MS method for the quantitation of amino acids, acylcarnitines, succinylacetone, and argininosuccinic acid in dried blood spotsAmino acids, acylcarnitinesTriple Quadrupole
Diseases and DisordersA reliable and simple FIA-MS/MS method for the quantitation of amino acids and acylcarnitines in dried blood spotsAmino acids, acylcarnitinesTriple Quadrupole
Therapeutic drug monitoringImmunosuppressants in dried blood spots by Transcend DSX-1 systemImmunosuppressantsTriple Quadrupole
EndocrinologyComparison of ionization types and precursor ions for quantitative analysis of 25-hydroxyvitamin D on TSQ Altis MD mass spectrometerVitamin DTriple Quadrupole
ToxicologyUtilizing HRAM Orbitrap mass spectrometry to quantitate 106 drugs of abuse in urineDrugs of AbuseHRAM MS
ToxicologyTriple Quadrupole LC-MS/MS method to quantitate 106 drugs of abuse in urineDrugs of AbuseTriple Quadrupole
Diseases and DisordersQuantitation of amino acids and acylcarnitines in DBS by FIA-Orbitrap mass spectrometry for Inborn Errors of MetabolismAmino acids and acylcarnitinesHRAM MS
Diseases and DisordersQuantification of amino acids, acylcarnitines, and succinylacetone in DBS by FIA-MS/MS for Inborn Errors of MetabolismAmino acids, acylcarnitines, and succinylacetoneTriple Quadrupole
Diseases and DisordersEnhancing detection of hemoglobin variants in clinical research using dried blood spot and high-resolution accurate mass (HRAM) Orbitrap mass spectrometryHemoglobinopathiesHRAM MS
BiomarkersQuantitation of lysosphingolipids in dried blood spots and plasma using high-resolution mass spectrometry for sphingolipidosesLysosphingolipids HRAM MS
Clinical researchImproved specificity for targeted LC-MS/MS measurements of 2,3-dinor-11β-prostaglandin F2α in urine using FAIMS technologyProstaglandinTriple Quadrupole / FAIMS