Product References
Distinct SARS-CoV-2 specific NLRP3 and IL-1β responses in T cells of aging patients during acute COVID-19 infection.
Frontiers in immunology
Mahalingam SS,Jayaraman S,Arunkumar A,Dudley HM,Anthony DD,Shive CL,Jacobson JM,Pandiyan P
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Flow Cytometry
Thu Oct 12 00:00:00 EDT 2023
Endosialin-positive tumor-derived pericytes promote tumor progression through impeding the infiltration of CD8+ T cells in clear cell renal cell carcinoma.
Cancer immunology, immunotherapy : CII
Lu T,Zhang J,Lu S,Yang F,Gan L,Wu X,Song H,Liu S,Xu C,Han D,Yang B,Wen W,Qin W,Yang L
11-0048-42 was used in Flow Cytometry to analyzed the relationship between endosialin (EN) expression and cytotoxic T-lymphocyte.
Thu Jun 01 00:00:00 EDT 2023
Estrogen Protects against Renal Ischemia-Reperfusion Injury by Regulating Th17/Treg Cell Immune Balance.
Disease markers
Zhang Y,Chang Y,Han Z,Ma K,Zeng X,Li L
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Flow Cytometry
Tue Oct 18 00:00:00 EDT 2022
Dysregulated Peripheral Invariant Natural Killer T Cells in Plaque Psoriasis Patients.
Frontiers in cell and developmental biology
Hu Y,Chen Y,Chen Z,Zhang X,Guo C,Yu Z,Xu P,Sun L,Zhou X,Gong Y,Yu Q,Shi Y
11-0048-42 was used in Flow cytometry/Cell sorting to explore the expression of iNKT cells in psoriasis patients and the effect of secukinumab on them.
Wed Feb 23 00:00:00 EST 2022
Plasma Extracellular Vesicle Subtypes May be Useful as Potential Biomarkers of Immune Activation in People With HIV.
Pathogens & immunity
Bazié WW,Boucher J,Vitry J,Goyer B,Routy JP,Tremblay C,Trottier S,Jenabian MA,Provost P,Alary M,Gilbert C
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Flow Cytometry
Sat Apr 23 00:00:00 EDT 2022
Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma.
Cell reports
Budhu S,Giese R,Gupta A,Fitzgerald K,Zappasodi R,Schad S,Hirschhorn D,Campesato LF,De Henau O,Gigoux M,Liu C,Mazo G,Deng L,Barker CA,Wolchok JD,Merghoub T
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Metabolic Disturbance and Th17/Treg Imbalance Are Associated With Progression of Gingivitis.
Frontiers in immunology
Wang W,Wang X,Lu S,Lv H,Zhao T,Xie G,Du Y,Fan Y,Xu L
11-0048-42 was used in Flow cytometry/Cell sorting to explore the role of metabolic disturbance in immunoregulation of gingivitis targeting T helper 17 cells/regulatory T cells.
Wed Oct 20 00:00:00 EDT 2021
Small-molecule antagonist of VLA-4 (GW559090) attenuated neuro-inflammation by targeting Th17 cell trafficking across the blood-retinal barrier in experimental autoimmune uveitis.
Journal of neuroinflammation
Chen YH,Eskandarpour M,Zhang X,Galatowicz G,Greenwood J,Lightman S,Calder V
11-0048-42 was used in Flow Cytometry to show that the α4β1 integrin inhibitor may exert a modulatory effect in EAU progression by selectively blocking Th17 cell migration across the blood-retinal barrier without affecting systemic CD4+ T cell subsets.
Thu Feb 18 00:00:00 EST 2021
Small-molecule antagonist of VLA-4 (GW559090) attenuated neuro-inflammation by targeting Th17 cell trafficking across the blood-retinal barrier in experimental autoimmune uveitis.
Journal of neuroinflammation
Chen YH,Eskandarpour M,Zhang X,Galatowicz G,Greenwood J,Lightman S,Calder V
11-0048-42 was used in Flow Cytometry to show that the α4β1 integrin inhibitor may exert a modulatory effect in EAU progression by selectively blocking Th17 cell migration across the blood-retinal barrier without affecting systemic CD4+ T cell subsets.
Thu Feb 18 00:00:00 EST 2021
Recombinant human IL-37 inhibited endometriosis development in a mouse model through increasing Th1/Th2 ratio by inducing the maturation of dendritic cells.
Reproductive biology and endocrinology : RB&E
Li L,Liao Z,Ye M,Jiang J
11-0048-42 was used in Flow cytometry/Cell sorting to study recombinant human IL-37 (rhIL-37) is an inhibitor of inflammation.
Tue Aug 24 00:00:00 EDT 2021
A Cross-Reactive Small Protein Binding Domain Provides a Model to Study Off-Tumor CAR-T Cell Toxicity.
Molecular therapy oncolytics
Hammill JA,Kwiecien JM,Dvorkin-Gheva A,Lau VWC,Baker C,Wu Y,Bezverbnaya K,Aarts C,Heslen CW,Denisova GF,Derocher H,Milne K,Nelson BH,Bramson JL
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Flow Cytometry
Fri Jun 26 00:00:00 EDT 2020
Potential of neutrophil to lymphocyte ratio in predicting sustained remission in rheumatoid arthritis compared to other immune activation markers.
The Indian journal of medical research
Chandrashekara S,Lingaraju DC,Renuka P,Anupama KR
11-0048 was used in Flow cytometry/Cell sorting to evaluate the role of cytokines and the immunocompetent cells as biomarkers of remission in rheumatoid arthritis (RA) patients intended to withdraw or reduce disease-modifying anti-rheumatic drug (DMARD) treatment.
Tue Sep 01 00:00:00 EDT 2020
CCL26 regulates the proportion of CD4+CD25+FOXP3+ Tregs and the production of inflammatory factors in peripheral blood mononuclear cells following acute ischemic stroke via the STAT5 pathway.
Experimental and therapeutic medicine
Dong Z,Cao L,Guo L,Hong Y,Cao J,Chen X
11-0048 was used in Flow cytometry/Cell sorting to investigate the role of C-C motif chemokine ligand 26(CCL26) in the regulation of regulatory T cells in acute ischemic stroke.
Thu Oct 01 00:00:00 EDT 2020
The anti-CXCL4 antibody depletes CD4(+)CD25(+)FOXP3(+) regulatory T cells in CD4+ T cells from chronic osteomyelitis patients by the STAT5 pathway.
Annals of palliative medicine
Huang K,Ge S
11-0048 was used in Flow cytometry/Cell sorting to investigate the effect of CXCL4, a member of chemokine family, on Tregs, and the underlying mechanisms.
Tue Sep 01 00:00:00 EDT 2020
The Potential of Nanobody-Targeted Photodynamic Therapy to Trigger Immune Responses.
Cancers
Beltrán Hernández I,Angelier ML,Del Buono D'Ondes T,Di Maggio A,Yu Y,Oliveira S
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Flow Cytometry
Wed Apr 15 00:00:00 EDT 2020
FOXO1 promotes HIV latency by suppressing ER stress in T cells.
Nature microbiology
Vallejo-Gracia A,Chen IP,Perrone R,Besnard E,Boehm D,Battivelli E,Tezil T,Krey K,Raymond KA,Hull PA,Walter M,Habrylo I,Cruz A,Deeks S,Pillai S,Verdin E,Ott M
11-0048 was used in Flow cytometry/Cell sorting to uncover a link of FOXO1, ER stress and HIV infection that could be therapeutically exploited to selectively reverse T-cell quiescence and reduce the size of the latent viral reservoir.
Tue Sep 01 00:00:00 EDT 2020
T-Lymphocyte Subset Distribution and Activity in Patients With Glaucoma.
Investigative ophthalmology & visual science
Yang X,Zeng Q,Göktas E,Gopal K,Al-Aswad L,Blumberg DM,Cioffi GA,Liebmann JM,Tezel G
11-0048 was used in Flow cytometry/Cell sorting to analyse T lymphocytes in patients' blood, to explore the T-cell-mediated component of systemic immunity.
Fri Mar 01 00:00:00 EST 2019
Umbilical cord blood‑derived Helios‑positive regulatory T cells promote angiogenesis in acute lymphoblastic leukemia in mice via CCL22 and the VEGFA‑VEGFR2 pathway.
Molecular medicine reports
Li X,Li D,Shi Q,Huang X,Ju X
11-0048 was used in Flow cytometry/Cell sorting to elucidate the mechanisms underlying the role of regulatory T cells in acute lymphoblastic leukaemia.
Wed May 01 00:00:00 EDT 2019
Increased expression of hub gene CXCL10 in peripheral blood mononuclear cells of patients with systemic lupus erythematosus.
Experimental and therapeutic medicine
Zhang R,Li Y,Pan B,Li Y,Liu A,Li X
11-0048 was used in Flow cytometry/Cell sorting to show that patients with systemic lupus erythematosus display an upregulation of CXCL10 in peripheral blood mononuclear cells.
Fri Nov 01 00:00:00 EDT 2019
Expression of CD20 after viral reactivation renders HIV-reservoir cells susceptible to Rituximab.
Nature communications
Serra-Peinado C,Grau-Expósito J,Luque-Ballesteros L,Astorga-Gamaza A,Navarro J,Gallego-Rodriguez J,Martin M,Curran A,Burgos J,Ribera E,Raventós B,Willekens R,Torrella A,Planas B,Badía R,Garcia F,Castellví J,Genescà M,Falcó V,Buzon MJ
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Flow Cytometry
Fri Aug 16 00:00:00 EDT 2019
TRIM28 promotes HIV-1 latency by SUMOylating CDK9 and inhibiting P-TEFb.
eLife
Ma X,Yang T,Luo Y,Wu L,Jiang Y,Song Z,Pan T,Liu B,Liu G,Liu J,Yu F,He Z,Zhang W,Yang J,Liang L,Guan Y,Zhang X,Li L,Cai W,Tang X,Gao S,Deng K,Zhang H
11-0048-42 was used in Flow Cytometry to show that TRIM28 potently suppresses HIV-1 expression by utilizing both SUMO E3 ligase activity and epigenetic adaptor function.
Thu Jan 17 00:00:00 EST 2019
Accumulation of T-helper 22 cells, interleukin-22 and myeloid-derived suppressor cells promotes gastric cancer progression in elderly patients.
Oncology letters
Chen X,Wang Y,Wang J,Wen J,Jia X,Wang X,Zhang H
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Flow Cytometry
Sun Jul 01 00:00:00 EDT 2018
Dysregulated ICOS+ proinflammatory and suppressive regulatory T cells in patients with rheumatoid arthritis.
Experimental and therapeutic medicine
Wang HX,Kang X,Chu S,Li H,Li X,Yin X,Qiu YR,Lai W
11-0048-42 was used in Flow cytometry/Cell sorting to suggest that ICOS+ Tregs may perform inflammatory and inhibitory functions, and abnormal ICOS+ Tregs numbers and functions may contribute to the pathogenesis of RA.
Mon Oct 01 00:00:00 EDT 2018
IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells.
Nature communications
Hsieh WC,Hsu TS,Chang YJ,Lai MZ
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Flow Cytometry
Wed Jan 31 00:00:00 EST 2018
Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism.
Nature communications
Arbore G,West EE,Rahman J,Le Friec G,Niyonzima N,Pirooznia M,Tunc I,Pavlidis P,Powell N,Li Y,Liu P,Servais A,Couzi L,Fremeaux-Bacchi V,Placais L,Ferraro A,Walsh PR,Kavanagh D,Afzali B,Lavender P,Lachmann HJ,Kemper C
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Flow Cytometry
Wed Oct 10 00:00:00 EDT 2018
High purity high yield tandem B and T helper cell isolation for qRT-PCR analysis suitable for basically equipped laboratories.
Malaria journal
Summerauer AM,Colombo L,Ogwang R,Berger C,Fehr J,Bürgler S
11-0048 was used in Flow cytometry/Cell sorting to describe a protocol that is likely to be of avail for many scientists performing malaria research in rural institutes or hospitals, and thus in countries where malaria is most prevalent.
Mon Oct 29 00:00:00 EDT 2018
Clinically compliant spatial and temporal imaging of chimeric antigen receptor T-cells.
Nature communications
Emami-Shahri N,Foster J,Kashani R,Gazinska P,Cook C,Sosabowski J,Maher J,Papa S
11-0048 was used in Flow cytometry/Cell sorting to show the utility of the human sodium iodide symporter (hNIS) for the temporal and spatial monitoring of CAR T-cell behavior in a cancer-bearing host.
Wed Mar 14 00:00:00 EDT 2018
MicroRNA-31 Targets Thymic Stromal Lymphopoietin in Mucosal Infiltrated CD4+ T Cells: A Role in Achieving Mucosal Healing in Ulcerative Colitis?
Inflammatory bowel diseases
Whiteoak SR,Claridge A,Balendran CA,Harris RJ,Gwiggner M,Bondanese VP,Erlandsson F,Hansen MB,Cummings JRF,Sanchez-Elsner T
11-0048-42 was used in Flow cytometry/Cell sorting to find that TSLP is reduced at both mRNA and protein levels in inflamed UC patients when compared with healthy subjects, in both whole biopsies and biopsy-isolated CD4+ CD25+ T cells.
Fri Oct 12 00:00:00 EDT 2018
Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation.
Cell
Lim AI,Li Y,Lopez-Lastra S,Stadhouders R,Paul F,Casrouge A,Serafini N,Puel A,Bustamante J,Surace L,Masse-Ranson G,David E,Strick-Marchand H,Le Bourhis L,Cocchi R,Topazio D,Graziano P,Muscarella LA,Rogge L,Norel X,Sallenave JM,Allez M,Graf T,Hendriks RW,Casanova JL,Amit I,Yssel H,Di Santo JP
11-0048 was used in Flow cytometry/Cell sorting to identify circulating and tissue ILC precursors in humans that fail to express the transcription factors and cytokine outputs of mature ILCs but have these signature loci in an epigenetically poised configuration.
Thu Mar 09 00:00:00 EST 2017
Landscape of Infiltrating T Cells in Liver Cancer Revealed by Single-Cell Sequencing.
Cell
Zheng C,Zheng L,Yoo JK,Guo H,Zhang Y,Guo X,Kang B,Hu R,Huang JY,Zhang Q,Liu Z,Dong M,Hu X,Ouyang W,Peng J,Zhang Z
11-0048 was used in Flow cytometry/Cell sorting to characterise the RNA expression of infiltrating T cells in liver cancer.
Thu Jun 15 00:00:00 EDT 2017
SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency.
Cell host & microbe
Boehm D,Jeng M,Camus G,Gramatica A,Schwarzer R,Johnson JR,Hull PA,Montano M,Sakane N,Pagans S,Godin R,Deeks SG,Krogan NJ,Greene WC,Ott M
11-0048 was used in Flow cytometry/Cell sorting to propose that a SMYD2-H4K20me1-L3MBTL1 axis contributes to HIV-1 latency and can be targeted with small-molecule SMYD2 inhibitors.
Wed May 10 00:00:00 EDT 2017
Ex vivo culture of human atherosclerotic plaques: A model to study immune cells in atherogenesis.
Atherosclerosis
Lebedeva A,Vorobyeva D,Vagida M,Ivanova O,Felker E,Fitzgerald W,Danilova N,Gontarenko V,Shpektor A,Vasilieva E,Margolis L
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2017
Hormonal vitamin D up-regulates tissue-specific PD-L1 and PD-L2 surface glycoprotein expression in humans but not mice.
The Journal of biological chemistry
Dimitrov V,Bouttier M,Boukhaled G,Salehi-Tabar R,Avramescu RG,Memari B,Hasaj B,Lukacs GL,Krawczyk CM,White JH
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Flow Cytometry
Fri Dec 15 00:00:00 EST 2017
Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation.
JCI insight
Tischner D,Grimm M,Kaur H,Staudenraus D,Carvalho J,Looso M,Günther S,Wanke F,Moos S,Siller N,Breuer J,Schwab N,Zipp F,Waisman A,Kurschus FC,Offermanns S,Wettschureck N
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Flow Cytometry
Thu Aug 03 00:00:00 EDT 2017
Targeted Disruption of TCF12 Reveals HEB as Essential in Human Mesodermal Specification and Hematopoiesis.
Stem cell reports
Li Y,Brauer PM,Singh J,Xhiku S,Yoganathan K,Zúñiga-Pflücker JC,Anderson MK
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Flow Cytometry
Tue Sep 12 00:00:00 EDT 2017
The β20-β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions.
Nature communications
Herschhorn A,Gu C,Moraca F,Ma X,Farrell M,Smith AB,Pancera M,Kwong PD,Schön A,Freire E,Abrams C,Blanchard SC,Mothes W,Sodroski JG
11-0048 was used in Flow cytometry/Cell sorting to identify the gp120 β20-β21 element as a major regulator of HIV-1 viral envelope glycoprotein conformational transitions.
Thu Oct 19 00:00:00 EDT 2017
CD3xPDL1 bi-specific T cell engager (BiTE) simultaneously activates T cells and NKT cells, kills PDL1+ tumor cells, and extends the survival of tumor-bearing humanized mice.
Oncotarget
Horn LA,Ciavattone NG,Atkinson R,Woldergerima N,Wolf J,Clements VK,Sinha P,Poudel M,Ostrand-Rosenberg S
11-0048 was used in Flow cytometry/Cell sorting to suggest that the CD3xPDL1 BiTE may be efficacious for patients with PDL1(+) solid tumors, in combination with other immunotherapies that do not specifically neutralize PD1 pathway-mediated immune suppression.
Tue Aug 29 00:00:00 EDT 2017
CD3xPDL1 bi-specific T cell engager (BiTE) simultaneously activates T cells and NKT cells, kills PDL1+ tumor cells, and extends the survival of tumor-bearing humanized mice.
Oncotarget
Horn LA,Ciavattone NG,Atkinson R,Woldergerima N,Wolf J,Clements VK,Sinha P,Poudel M,Ostrand-Rosenberg S
11-0048 was used in Flow cytometry/Cell sorting to suggest that the CD3xPDL1 BiTE may be efficacious for patients with PDL1(+) solid tumors, in combination with other immunotherapies that do not specifically neutralize PD1 pathway-mediated immune suppression.
Tue Aug 29 00:00:00 EDT 2017
Oroxylin A inhibits the generation of Tregs in non-small cell lung cancer.
Oncotarget
Shen L,Zhang LL,Li H,Liu X,Yu XX,Hu P,Hui H,Guo QL,Zhang S
11-0048 was used in Flow cytometry/Cell sorting to demonstrate that oroxylin A inhibits Treg generation in lung cancer by inhibiting TGF-β1 response and secretion via NF-κB signalling.
Tue Jul 25 00:00:00 EDT 2017
PD-L1 expression and prognostic impact in glioblastoma.
Neuro-oncology
Nduom EK,Wei J,Yaghi NK,Huang N,Kong LY,Gabrusiewicz K,Ling X,Zhou S,Ivan C,Chen JQ,Burks JK,Fuller GN,Calin GA,Conrad CA,Creasy C,Ritthipichai K,Radvanyi L,Heimberger AB
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2016
Altered expression of miR-92a correlates with Th17 cell frequency in patients with primary biliary cirrhosis.
International journal of molecular medicine
Liang DY,Hou YQ,Luo LJ,Ao L
11-0048 was used in Flow cytometry/Cell sorting to study the altered expression of miR-92a and its impact on the frequency of Th17 cells in patients with primary biliary cirrhosis.
Fri Jul 01 00:00:00 EDT 2016
Tax and Semaphorin 4D Released from Lymphocytes Infected with Human Lymphotropic Virus Type 1 and Their Effect on Neurite Growth.
AIDS research and human retroviruses
Quintremil S,Alberti C,Rivera M,Medina F,Puente J,Cartier L,Ramírez E,Tanaka Y,Valenzuela MA
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets.
Scientific reports
Muller L,Mitsuhashi M,Simms P,Gooding WE,Whiteside TL
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Flow Cytometry
Thu Feb 04 00:00:00 EST 2016
PSG9 Stimulates Increase in FoxP3+ Regulatory T-Cells through the TGF-β1 Pathway.
PloS one
Jones K,Ballesteros A,Mentink-Kane M,Warren J,Rattila S,Malech H,Kang E,Dveksler G
11-0048 was used in Flow cytometry/Cell sorting to investigate whether pregnancy-specific glycoprotein 9, a potential predictive biomarker of pre-eclampsia, plays an immunoregulatory role during pregnancy.
Wed Jul 26 00:00:00 EDT 2017
The Expression of Programmed Death-1 on CD4+ and CD8+ T Lymphocytes in Patients with Type 2 Diabetes and Severe Sepsis.
PloS one
Jia Y,Zhao Y,Li C,Shao R
11-0048 was used in Flow cytometry/Cell sorting to investigate the expression of Programmed death-1 on T lymphocytes in patients with type 2 diabetes mellitus and severe sepsis.
Mon Jul 24 00:00:00 EDT 2017
A Systematic Study of the Effect of Different Molecular Weights of Hyaluronic Acid on Mesenchymal Stromal Cell-Mediated Immunomodulation.
PloS one
Gómez-Aristizábal A,Kim KP,Viswanathan S
11-0048 was used in Flow cytometry/Cell sorting to investigate the combined mechanism of action of MSCs and hyaluronic acid.
Wed Jul 06 00:00:00 EDT 2016
Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease.
Nature medicine
Chimen M,McGettrick HM,Apta B,Kuravi SJ,Yates CM,Kennedy A,Odedra A,Alassiri M,Harrison M,Martin A,Barone F,Nayar S,Hitchcock JR,Cunningham AF,Raza K,Filer A,Copland DA,Dick AD,Robinson J,Kalia N,Walker LSK,Buckley CD,Nash GB,Narendran P,Rainger GE
11-0048 was used in Flow cytometry/Cell sorting to demonstrate that exogenous PEPITEM reduces T cell recruitment into inflamed tissues in multiple animal models of autoimmune, inflammatory diseases.
Fri May 01 00:00:00 EDT 2015
Low B and T lymphocyte attenuator expression on CD4+ T cells in the early stage of sepsis is associated with the severity and mortality of septic patients: a prospective cohort study.
Critical care (London, England)
Shao R,Li CS,Fang Y,Zhao L,Hang C
11-0048 was used in Flow cytometry/Cell sorting to investigate B and T lymphocyte attenuator expression on CD4(+) T cells in healthy controls and septic patients.
Fri Aug 28 00:00:00 EDT 2015
The HIV-1 gp120 CD4-bound conformation is preferentially targeted by antibody-dependent cellular cytotoxicity-mediating antibodies in sera from HIV-1-infected individuals.
Journal of virology
Veillette M,Coutu M,Richard J,Batraville LA,Dagher O,Bernard N,Tremblay C,Kaufmann DE,Roger M,Finzi A
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
Skewed T-helper (Th)1/2- and Th17/T regulatory‑cell balances in patients with renal cell carcinoma.
Molecular medicine reports
Li L,Yang C,Zhao Z,Xu B,Zheng M,Zhang C,Min Z,Guo J,Rong R
11-0048 was used in Flow cytometry/Cell sorting to demonstrate that the balance of Th1 and Th2 cells is skewed towards the Th2 profile in the peripheral blood of patients with RCC.
Sun Feb 01 00:00:00 EST 2015
Aging and cytomegalovirus infection differentially and jointly affect distinct circulating T cell subsets in humans.
Journal of immunology (Baltimore, Md. : 1950)
Wertheimer AM,Bennett MS,Park B,Uhrlaub JL,Martinez C,Pulko V,Currier NL,Nikolich-Žugich D,Kaye J,Nikolich-Žugich J
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Flow Cytometry
Sat Mar 01 00:00:00 EST 2014
Calcium signaling via Orai1 is essential for induction of the nuclear orphan receptor pathway to drive Th17 differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Kim KD,Srikanth S,Tan YV,Yee MK,Jew M,Damoiseaux R,Jung ME,Shimizu S,An DS,Ribalet B,Waschek JA,Gwack Y
11-0048 was used in Flow cytometry/Cell sorting to identify a novel class of small molecules that inhibit Ca(2+) release-activated Ca(2+) channel activity.
Wed Jan 01 00:00:00 EST 2014
An increased abundance of tumor-infiltrating regulatory T cells is correlated with the progression and prognosis of pancreatic ductal adenocarcinoma.
PloS one
Tang Y,Xu X,Guo S,Zhang C,Tang Y,Tian Y,Ni B,Lu B,Wang H
11-0048 was used in Flow cytometry/Cell sorting to reveal Tregs may promote PDA progression by inhibiting the antitumour immunity of CD8+ T cells at local intratumoural sites.
Tue Jan 06 00:00:00 EST 2015
An increased abundance of tumor-infiltrating regulatory T cells is correlated with the progression and prognosis of pancreatic ductal adenocarcinoma.
PloS one
Tang Y,Xu X,Guo S,Zhang C,Tang Y,Tian Y,Ni B,Lu B,Wang H
11-0048 was used in Flow cytometry/Cell sorting to reveal Tregs may promote PDA progression by inhibiting the antitumour immunity of CD8+ T cells at local intratumoural sites.
Tue Jan 06 00:00:00 EST 2015
Azithromycin suppresses CD4(+) T-cell activation by direct modulation of mTOR activity.
Scientific reports
Ratzinger F,Haslacher H,Poeppl W,Hoermann G,Kovarik JJ,Jutz S,Steinberger P,Burgmann H,Pickl WF,Schmetterer KG
11-0048 was used in Flow cytometry/Cell sorting to evaluate the in vitro effects of the antibiotics azithromycin and clarithromycin on the activation of CD4(+) T cells.
Thu Dec 11 00:00:00 EST 2014
Association of a NOD2 gene polymorphism and T-helper 17 cells with presumed ocular toxoplasmosis.
The Journal of infectious diseases
Dutra MS,Béla SR,Peixoto-Rangel AL,Fakiola M,Cruz AG,Gazzinelli A,Quites HF,Bahia-Oliveira LM,Peixe RG,Campos WR,Higino-Rocha AC,Miller NE,Blackwell JM,Antonelli LR,Gazzinelli RT
11-0048 was used in Flow cytometry/Cell sorting to suggest that NOD2 influences the production of IL-17A by CD4 T lymphocytes and might contribute to the development of ocular toxoplasmosis.
Tue Jan 01 00:00:00 EST 2013
Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset.
PLoS pathogens
Lindestam Arlehamn CS,Gerasimova A,Mele F,Henderson R,Swann J,Greenbaum JA,Kim Y,Sidney J,James EA,Taplitz R,McKinney DM,Kwok WW,Grey H,Sallusto F,Peters B,Sette A
11-0048 was used in Flow cytometry/Cell sorting to further define the immunological footprint of Mycobacterium tuberculosis CD4 T cell recognition.
Tue Jan 01 00:00:00 EST 2013
Th17/Treg imbalance in patients with liver cystic echinococcosis.
Parasite immunology
Tuxun T,Wang JH,Lin RY,Shan JY,Tai QW,Li T,Zhang JH,Zhao JM,Wen H
11-0048-42 was used in Flow cytometry/Cell sorting to indicate that Th17/Treg functional imbalance exists in patients with chronic cystic echinococcosis, suggesting a potential role for Th17/Treg imbalance in the pathogenesis of immune evasion in echinococcosis.
Thu Nov 01 00:00:00 EDT 2012
Role of gastric epithelial cell-derived transforming growth factor beta in reduced CD4+ T cell proliferation and development of regulatory T cells during Helicobacter pylori infection.
Infection and immunity
Beswick EJ,Pinchuk IV,Earley RB,Schmitt DA,Reyes VE
11-0048 was used in Flow cytometry/Cell sorting to show how TGF-β produced by gastric epithelial cells inhibits CD4+ T cell responses during H. pylori infection, suggesting a possible mechanism of persistence.
Fri Jul 01 00:00:00 EDT 2011
Common gamma chain cytokines promote rapid in vitro expansion of allo-specific human CD8+ suppressor T cells.
PloS one
Yu Y,Zitzner JR,Houlihan J,Herrera N,Xu L,Miller J,Mathew JM,Tambur AR,Luo X
11-0048 was used in Flow cytometry/Cell sorting to demonstrate the use of common γc cytokines in combination with donor APCs as a strategy for generation of donor-specific T cells for immunotherapy.
Mon Aug 27 00:00:00 EDT 2012
Assessment of seasonal influenza A virus-specific CD4 T-cell responses to 2009 pandemic H1N1 swine-origin influenza A virus.
Journal of virology
Ge X,Tan V,Bollyky PL,Standifer NE,James EA,Kwok WW
11-0048 was used in Flow cytometry/Cell sorting to investigate how, without protective antibody responses, individuals vaccinated against seasonal influenza A may still benefit from preexisting cross-reactive memory CD4 T cells reducing their susceptibility to S-OIV infection.
Thu Apr 01 00:00:00 EDT 2010
CD4-CCR5 interaction in intracellular compartments contributes to receptor expression at the cell surface.
Blood
Achour L,Scott MG,Shirvani H,Thuret A,Bismuth G,Labbé-Jullié C,Marullo S
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Immunofluorescence
Thu Feb 26 00:00:00 EST 2009
CD4-CCR5 interaction in intracellular compartments contributes to receptor expression at the cell surface.
Blood
Achour L,Scott MG,Shirvani H,Thuret A,Bismuth G,Labbé-Jullié C,Marullo S
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Immunofluorescence
Thu Feb 26 00:00:00 EST 2009
CD4-CCR5 interaction in intracellular compartments contributes to receptor expression at the cell surface.
Blood
Achour L,Scott MG,Shirvani H,Thuret A,Bismuth G,Labbé-Jullié C,Marullo S
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Immunofluorescence
Thu Feb 26 00:00:00 EST 2009
CD4-CCR5 interaction in intracellular compartments contributes to receptor expression at the cell surface.
Blood
Achour L,Scott MG,Shirvani H,Thuret A,Bismuth G,Labbé-Jullié C,Marullo S
Published figure using CD4 monoclonal antibody (Product # 11-0048-42) in Immunofluorescence
Thu Feb 26 00:00:00 EST 2009
Naive CD4 t cell proliferation is controlled by mammalian target of rapamycin regulation of GRAIL expression.
Journal of immunology (Baltimore, Md. : 1950)
Lin JT,Lineberry NB,Kattah MG,Su LL,Utz PJ,Fathman CG,Wu L
11-0048 was used in Flow cytometry/Cell sorting to investigate the role of GRAIL in CD4 T cells, showing that proliferation is controlled by mTOR regulation of GRAIL expression.
Fri May 15 00:00:00 EDT 2009
T-cell responses to survivin in cancer patients undergoing radiation therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research
Schaue D,Comin-Anduix B,Ribas A,Zhang L,Goodglick L,Sayre JW,Debucquoy A,Haustermans K,McBride WH
11-0048 was used in Flow cytometry/Cell sorting to show that radiation therapy may increase the likelihood of some cancer patients responding to immunotherapy.
Fri Aug 01 00:00:00 EDT 2008
TCR-induced downregulation of protein tyrosine phosphatase PEST augments secondary T cell responses.
Molecular immunology
Arimura Y,Vang T,Tautz L,Williams S,Mustelin T
11-0048 was used in Flow cytometry/Cell sorting to investigate how PTP-PEST is down-regulated following T cell activation, and how that can lead to reduced IL-2 secretion following TCR and CD28 stimulation.
Sun Jun 01 00:00:00 EDT 2008
T regulatory cell levels decrease in people infected with Schistosoma mansoni on effective treatment.
The American journal of tropical medicine and hygiene
Watanabe K,Mwinzi PN,Black CL,Muok EM,Karanja DM,Secor WE,Colley DG
11-0048 was used in Flow cytometry/Cell sorting to investigate the role of Tregs in Schistosoma mansoni infection, showing that Treg levels decrease in people on effective treatment.
Mon Oct 01 00:00:00 EDT 2007
