Product References
Spleen-targeted neoantigen DNA vaccine for personalized immunotherapy of hepatocellular carcinoma.
EMBO molecular medicine
Wu M,Luo Z,Cai Z,Mao Q,Li Z,Li H,Zhang C,Zhang Y,Zhong A,Wu L,Liu X
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Wed Oct 11 00:00:00 EDT 2023
Involvement of langerin in the protective function of a keratan sulfate-based disaccharide in an emphysema mouse model.
The Journal of biological chemistry
Ohkawa Y,Kanto N,Nakano M,Fujinawa R,Kizuka Y,Johnson EL,Harada Y,Tamura JI,Taniguchi N
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2023
Oncolytic virus M1 functions as a bifunctional checkpoint inhibitor to enhance the antitumor activity of DC vaccine.
Cell reports. Medicine
Dan J,Cai J,Zhong Y,Wang C,Huang S,Zeng Y,Fan Z,Xu C,Hu L,Zhang J,Hu J,Liu Y,Su X,Zhu W,Yan G,Liang J,Lin Y
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2023
Toxin expression during Staphylococcus aureus infection imprints host immunity to inhibit vaccine efficacy.
NPJ vaccines
Teymournejad O,Li Z,Beesetty P,Yang C,Montgomery CP
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Tue Jan 24 00:00:00 EST 2023
Anti-tumor effects of anti-programmed cell death-1 antibody treatment are attenuated in streptozotocin-induced diabetic mice.
Scientific reports
Ito M,Iwama S,Sugiyama D,Yasuda Y,Okuji T,Kobayashi T,Zhou X,Yamagami A,Onoue T,Miyata T,Sugiyama M,Hagiwara D,Suga H,Banno R,Nishikawa H,Arima H
14-0114-82 was used in Immunohistochemistry to suggest that the STZ-induced hyperglycemia impairs the effect of PD-1-Ab treatment on MC38 tumor growth, and is accompanied by reduced infiltration of DCs and CD8+ T cells and decreased expression of CCL7 and CXCL9.
Wed Apr 12 00:00:00 EDT 2023
Topical Diacerein Decreases Skin and Splenic CD11c+ Dendritic Cells in Psoriasis.
International journal of molecular sciences
Brunner SM,Ramspacher A,Rieser C,Leitner J,Heil H,Ablinger M,Tevini J,Wimmer M,Koller A,Piñón Hofbauer J,Felder TK,Bauer JW,Kofler B,Lang R,Wally V
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Tue Feb 21 00:00:00 EST 2023
Outer Membrane Vesicle-Coated Nanoparticle Vaccine Protects Against Acinetobacter baumannii Pneumonia and Sepsis.
Advanced nanobiomed research
Bjanes E,Zhou J,Qayum T,Krishnan N,Zurich RH,Menon ND,Hoffman A,Fang RH,Zhang L,Nizet V
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2023
CD11c+ microglia promote white matter repair after ischemic stroke.
Cell death & disease
Jia J,Zheng L,Ye L,Chen J,Shu S,Xu S,Bao X,Xia S,Liu R,Xu Y,Zhang M
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Feb 24 00:00:00 EST 2023
CD11c+ microglia promote white matter repair after ischemic stroke.
Cell death & disease
Jia J,Zheng L,Ye L,Chen J,Shu S,Xu S,Bao X,Xia S,Liu R,Xu Y,Zhang M
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Feb 24 00:00:00 EST 2023
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
P. gingivalis Infection Upregulates PD-L1 Expression on Dendritic Cells, Suppresses CD8+ T-cell Responses, and Aggravates Oral Cancer.
Cancer immunology research
Ren J,Han X,Lohner H,Hoyle RG,Li J,Liang S,Wang H
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
Monocytes reprogrammed by tumor microparticle vaccine inhibit tumorigenesis and tumor development.
Cancer nanotechnology
Sun W,Dai L,Cao Y,Pan P,Zhi L,Wang X,Yuan X,Gao Z,Guo S,Liu G,Yin J,Xie L,Wang L,Wang Y,Li W,Li H,Jia Y
14-0114-82 was used in Flow cytometry/Cell sorting to provide novel vaccination strategy for the development of tumor vaccines and facilitate the application of T-MPs for clinic oncotherapy.
Tue Apr 25 00:00:00 EDT 2023
Inhibition of Macrophage-Specific CHIT1 as an Approach to Treat Airway Remodeling in Severe Asthma.
International journal of molecular sciences
Sklepkiewicz P,Dymek B,Mlacki M,Zagozdzon A,Salamon M,Siwińska AM,Mazurkiewicz MP,de Souza Xavier Costa N,Mazur M,Mauad T,Gołębiowski A,Dzwonek K,Gołąb J,Zasłona Z
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
MHC class I and MHC class II reporter mice enable analysis of immune oligodendroglia in mouse models of multiple sclerosis.
eLife
Harrington EP,Catenacci RB,Smith MD,Heo D,Miller CE,Meyers KR,Glatzer J,Bergles DE,Calabresi PA
14-0114-82 was used in Immunohistochemistry to define oligodendrocytes and their progenitors in response to inflammatory demyelination, providing a means to monitor MHC activation in diverse cell types in living mice and define their roles in aging, injury, and disease.
Fri Apr 14 00:00:00 EDT 2023
Targeted inhibition of osteoclastogenesis reveals the pathogenesis and therapeutics of bone loss under sympathetic neurostress.
International journal of oral science
Sui B,Liu J,Zheng C,Dang L,Chen J,Cao Y,Zhang K,Liu L,Dang M,Zhang L,Chen N,He T,Xuan K,Jin F,Zhang G,Jin Y,Hu C
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunohistochemistry
Mon Aug 01 00:00:00 EDT 2022
Meningeal lymphatic drainage promotes T cell responses against Toxoplasma gondii but is dispensable for parasite control in the brain.
eLife
Kovacs MA,Cowan MN,Babcock IW,Sibley LA,Still K,Batista SJ,Labuzan SA,Sethi I,Harris TH
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Wed Dec 21 00:00:00 EST 2022
Interferon-γ Stimulates Interleukin-27 Derived from Dendritic Cells to Regulate Th9 Differentiation through STAT1/3 Pathway.
Disease markers
Xiong P,Liu T,Chen Y,Xu Q,Hu X,Han F,Shi L
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Mon Oct 31 00:00:00 EDT 2022
Neutrophil-dendritic cell interaction plays an important role in live attenuated Leishmania vaccine induced immunity.
PLoS neglected tropical diseases
Bhattacharya P,Ismail N,Saxena A,Gannavaram S,Dey R,Oljuskin T,Akue A,Takeda K,Yu J,Karmakar S,Dagur PK,McCoy JP,Nakhasi HL
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Tue Feb 01 00:00:00 EST 2022
Self-Tolerance of Vascular Tissues Is Broken Down by Vascular Dendritic Cells in Response to Systemic Inflammation to Initiate Regional Autoinflammation.
Frontiers in immunology
Sun L,Zhang W,Zhao L,Zhao Y,Wang F,Lew AM,Xu Y
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunohistochemistry
Fri Apr 01 00:00:00 EDT 2022
Nucleolin Therapeutic Targeting Decreases Pancreatic Cancer Immunosuppression.
Cancers
Ponzo M,Debesset A,Cossutta M,Chalabi-Dchar M,Houppe C,Pilon C,Nicolas-Boluda A,Meunier S,Raineri F,Thiolat A,Nicolle R,Maione F,Brundu S,Cojocaru CF,Bouvet P,Bousquet C,Gazeau F,Tournigand C,Courty J,Giraudo E,Cohen JL,Cascone I
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Wed Aug 31 00:00:00 EDT 2022
Single-cell transcriptomics reveals distinct cell response between acute and chronic pulmonary infection of Pseudomonas aeruginosa.
MedComm
Hu X,Wu M,Ma T,Zhang Y,Zou C,Wang R,Zhang Y,Ren Y,Li Q,Liu H,Li H,Wang T,Sun X,Yang Y,Tang M,Li X,Li J,Gao X,Li T,Zhou X
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunohistochemistry
Thu Dec 01 00:00:00 EST 2022
Single-cell transcriptomics reveals distinct cell response between acute and chronic pulmonary infection of Pseudomonas aeruginosa.
MedComm
Hu X,Wu M,Ma T,Zhang Y,Zou C,Wang R,Zhang Y,Ren Y,Li Q,Liu H,Li H,Wang T,Sun X,Yang Y,Tang M,Li X,Li J,Gao X,Li T,Zhou X
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunohistochemistry
Thu Dec 01 00:00:00 EST 2022
TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration.
Nature neuroscience
Xie M,Liu YU,Zhao S,Zhang L,Bosco DB,Pang YP,Zhong J,Sheth U,Martens YA,Zhao N,Liu CC,Zhuang Y,Wang L,Dickson DW,Mattson MP,Bu G,Wu LJ
14-0114-82 was used in Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation to highlight that TDP-43 is a possible ligand for microglial TREM2 and that this interaction mediates neuroprotection of microglia in TDP-43-related neurodegeneration.
Sat Jan 01 00:00:00 EST 2022
An immunocompetent rectal cancer model to study radiation therapy.
Cell reports methods
Kim JK,Wu C,Del Latto M,Gao Y,Choi SH,Kierstead M,Gabriel Sauvé CE,Firat C,Perez AC,Sillanpaa J,Chen CT,Lawrence KE,Paty PB,Barriga FM,Wilkinson JE,Shia J,Sawyers CL,Lowe SW,García-Aguilar J,Romesser PB,Smith JJ
14-0114-82 was used in Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation to describe a mouse model of rectal cancer (RC) involving rapid tumor organoid engraftment via orthotopic transplantation in an immunocompetent setting.
Mon Dec 19 00:00:00 EST 2022
Immunological conversion of solid tumours using a bispecific nanobioconjugate for cancer immunotherapy.
Nature nanotechnology
Lu Y,Huntoon K,Lee D,Wang Y,Ha J,Qie Y,Li X,Schrank BR,Dong S,Gallup TD,Kang M,Zhao H,An Y,Yang Z,Li J,Kim BYS,Jiang W
14-0114-82 was used in Immunohistochemistry-immunofluorescence to support an immunological conversion strategy that uses nano-adjuvants to improve the effectiveness of immunotherapies for solid tumours.
Thu Dec 01 00:00:00 EST 2022
Candida tropicalis Infection Modulates the Gut Microbiome and Confers Enhanced Susceptibility to Colitis in Mice.
Cellular and molecular gastroenterology and hepatology
Di Martino L,De Salvo C,Buela KA,Hager C,Ghannoum M,Osme A,Buttò L,Bamias G,Pizarro TT,Cominelli F
14-0114-82 was used in Flow Cytometry to determine the effects and mechanisms of action of Candida tropicalis on intestinal inflammation and injury in mouse models.
Mon Apr 04 00:00:00 EDT 2022
Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia.
The Journal of experimental medicine
Zhao N,Qiao W,Li F,Ren Y,Zheng J,Martens YA,Wang X,Li L,Liu CC,Chen K,Zhu Y,Ikezu TC,Li Z,Meneses AD,Jin Y,Knight JA,Chen Y,Bastea L,Linares C,Sonustun B,Job L,Smith ML,Xie M,Liu YU,Umpierre AD,Haruwaka K,Quicksall ZS,Storz P,Asmann YW,Wu LJ,Bu G
14-0114-82 was used in Immunohistochemistry-immunofluorescence to highlight the dynamic effects of TREM2 in modulating AD pathogenesis and emphasize the beneficial effect of enhancing TREM2 function in the early stage of AD development.
Mon Dec 05 00:00:00 EST 2022
Neutrophil-specific gain-of-function mutations in Nlrp3 promote development of cryopyrin-associated periodic syndrome.
The Journal of experimental medicine
Stackowicz J,Gaudenzio N,Serhan N,Conde E,Godon O,Marichal T,Starkl P,Balbino B,Roers A,Bruhns P,Jönsson F,Moguelet P,Georgin-Lavialle S,Broderick L,Hoffman HM,Galli SJ,Reber LL
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunohistochemistry
Mon Oct 04 00:00:00 EDT 2021
Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin.
Cell death and differentiation
Velletri T,Huang Y,Wang Y,Li Q,Hu M,Xie N,Yang Q,Chen X,Chen Q,Shou P,Gan Y,Candi E,Annicchiarico-Petruzzelli M,Agostini M,Yang H,Melino G,Shi Y,Wang Y
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Depletion of Adipocyte Becn1 Leads to Lipodystrophy and Metabolic Dysregulation.
Diabetes
Jin Y,Ji Y,Song Y,Choe SS,Jeon YG,Na H,Nam TW,Kim HJ,Nahmgoong H,Kim SM,Kim JW,Nam KT,Seong JK,Hwang D,Park CB,Lee IH,Kim JB,Lee HW
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Depletion of Adipocyte Becn1 Leads to Lipodystrophy and Metabolic Dysregulation.
Diabetes
Jin Y,Ji Y,Song Y,Choe SS,Jeon YG,Na H,Nam TW,Kim HJ,Nahmgoong H,Kim SM,Kim JW,Nam KT,Seong JK,Hwang D,Park CB,Lee IH,Kim JB,Lee HW
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Depletion of Adipocyte Becn1 Leads to Lipodystrophy and Metabolic Dysregulation.
Diabetes
Jin Y,Ji Y,Song Y,Choe SS,Jeon YG,Na H,Nam TW,Kim HJ,Nahmgoong H,Kim SM,Kim JW,Nam KT,Seong JK,Hwang D,Park CB,Lee IH,Kim JB,Lee HW
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Induction of IL-12p40 and type 1 immunity by Toxoplasma gondii in the absence of the TLR-MyD88 signaling cascade.
PLoS pathogens
Snyder LM,Doherty CM,Mercer HL,Denkers EY
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Oct 01 00:00:00 EDT 2021
Pancreatic Cancer Chemotherapy Is Potentiated by Induction of Tertiary Lymphoid Structures in Mice.
Cellular and molecular gastroenterology and hepatology
Delvecchio FR,Fincham REA,Spear S,Clear A,Roy-Luzarraga M,Balkwill FR,Gribben JG,Bombardieri M,Hodivala-Dilke K,Capasso M,Kocher HM
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Mon Mar 28 00:00:00 EDT 2022
T cell-derived tumor necrosis factor induces cytotoxicity by activating RIPK1-dependent target cell death.
JCI insight
Chun N,Ang RL,Chan M,Fairchild RL,Baldwin WM,Horwitz JK,Gelles JD,Chipuk JE,Kelliher MA,Pavlov VI,Li Y,Homann D,Heeger PS,Ting AT
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Wed Dec 22 00:00:00 EST 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
Enrichment of Neurodegenerative Microglia Signature in Brain-Derived Extracellular Vesicles Isolated from Alzheimer's Disease Mouse Models.
Journal of proteome research
Muraoka S,Jedrychowski MP,Iwahara N,Abdullah M,Onos KD,Keezer KJ,Hu J,Ikezu S,Howell GR,Gygi SP,Ikezu T
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Western Blot
Fri Mar 05 00:00:00 EST 2021
Intratumoral injection of TLR9 agonist promotes an immunopermissive microenvironment transition and causes cooperative antitumor activity in combination with anti-PD1 in pancreatic cancer.
Journal for immunotherapy of cancer
Carbone C,Piro G,Agostini A,Delfino P,De Sanctis F,Nasca V,Spallotta F,Sette C,Martini M,Ugel S,Corbo V,Cappello P,Bria E,Scarpa A,Tortora G
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Wed Sep 01 00:00:00 EDT 2021
STING activation normalizes the intraperitoneal vascular-immune microenvironment and suppresses peritoneal carcinomatosis of colon cancer.
Journal for immunotherapy of cancer
Lee SJ,Yang H,Kim WR,Lee YS,Lee WS,Kong SJ,Lee HJ,Kim JH,Cheon J,Kang B,Chon HJ,Kim C
14-0114-82 was used in Flow Cytometry to elucidate the immune-evasion mechanisms during the peritoneal carcinomatosis of colon cancer and developed a novel immunotherapy by activating the stimulator of interferon genes (STING) pathway.
Tue Jun 01 00:00:00 EDT 2021
Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer.
Cell research
Wang S,Qu Y,Xia P,Chen Y,Zhu X,Zhang J,Wang G,Tian Y,Ying J,Fan Z
14-0114-82 was used in Flow Cytometry to profile tumor infiltrating innate lymphoid cells in colorectal cancer at early and late stages.
Wed Jul 01 00:00:00 EDT 2020
Dual-Wavelength Photosensitive Nano-in-Micro Scaffold Regulates Innate and Adaptive Immune Responses for Osteogenesis.
Nano-micro letters
Zhao Q,Shi M,Yin C,Zhao Z,Zhang J,Wang J,Shen K,Zhang L,Tang H,Xiao Y,Zhang Y
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Sat Nov 21 00:00:00 EST 2020
Dual-Wavelength Photosensitive Nano-in-Micro Scaffold Regulates Innate and Adaptive Immune Responses for Osteogenesis.
Nano-micro letters
Zhao Q,Shi M,Yin C,Zhao Z,Zhang J,Wang J,Shen K,Zhang L,Tang H,Xiao Y,Zhang Y
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Sat Nov 21 00:00:00 EST 2020
B cells are sufficient to prime the dominant CD4+ Tfh response to Plasmodium infection.
The Journal of experimental medicine
Arroyo EN,Pepper M
14-0114-82 was used in Flow Cytometry to study antigen-specific CD4+ T follicular helper (Tfh) cells responding to Plasmodium infection in order to understand the generation and maintenance of the Tfh response.
Mon Feb 03 00:00:00 EST 2020
Glufosinate constrains synchronous and metachronous metastasis by promoting anti-tumor macrophages.
EMBO molecular medicine
Menga A,Serra M,Todisco S,Riera-Domingo C,Ammarah U,Ehling M,Palmieri EM,Di Noia MA,Gissi R,Favia M,Pierri CL,Porporato PE,Castegna A,Mazzone M
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunohistochemistry (Paraffin)
Wed Oct 07 00:00:00 EDT 2020
Glufosinate constrains synchronous and metachronous metastasis by promoting anti-tumor macrophages.
EMBO molecular medicine
Menga A,Serra M,Todisco S,Riera-Domingo C,Ammarah U,Ehling M,Palmieri EM,Di Noia MA,Gissi R,Favia M,Pierri CL,Porporato PE,Castegna A,Mazzone M
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunohistochemistry (Paraffin)
Wed Oct 07 00:00:00 EDT 2020
Glufosinate constrains synchronous and metachronous metastasis by promoting anti-tumor macrophages.
EMBO molecular medicine
Menga A,Serra M,Todisco S,Riera-Domingo C,Ammarah U,Ehling M,Palmieri EM,Di Noia MA,Gissi R,Favia M,Pierri CL,Porporato PE,Castegna A,Mazzone M
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunohistochemistry (Paraffin)
Wed Oct 07 00:00:00 EDT 2020
Glufosinate constrains synchronous and metachronous metastasis by promoting anti-tumor macrophages.
EMBO molecular medicine
Menga A,Serra M,Todisco S,Riera-Domingo C,Ammarah U,Ehling M,Palmieri EM,Di Noia MA,Gissi R,Favia M,Pierri CL,Porporato PE,Castegna A,Mazzone M
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunohistochemistry (Paraffin)
Wed Oct 07 00:00:00 EDT 2020
Inflammation shapes pathogenesis of murine arrhythmogenic cardiomyopathy.
Basic research in cardiology
Lubos N,van der Gaag S,Gerçek M,Kant S,Leube RE,Krusche CA
14-0114 was used in Immunohistochemistry to investigate if specific immune cell populations and chemokine expression profiles modulate inflammatory and repair processes throughout arrhythmogenic cardiomyopathy progression.
Fri Jun 12 00:00:00 EDT 2020
Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.
British journal of pharmacology
De Cicco P,Ercolano G,Rubino V,Terrazzano G,Ruggiero G,Cirino G,Ianaro A
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
oHSV2 Can Target Murine Colon Carcinoma by Altering the Immune Status of the Tumor Microenvironment and Inducing Antitumor Immunity.
Molecular therapy oncolytics
Zhang W,Hu X,Liang J,Zhu Y,Zeng B,Feng L,Zhao C,Liu S,Liu B,Zhang K
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Mar 27 00:00:00 EDT 2020
oHSV2 Can Target Murine Colon Carcinoma by Altering the Immune Status of the Tumor Microenvironment and Inducing Antitumor Immunity.
Molecular therapy oncolytics
Zhang W,Hu X,Liang J,Zhu Y,Zeng B,Feng L,Zhao C,Liu S,Liu B,Zhang K
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Mar 27 00:00:00 EDT 2020
Secreted Phospholipase A2 Group X Acts as an Adjuvant for Type 2 Inflammation, Leading to an Allergen-Specific Immune Response in the Lung.
Journal of immunology (Baltimore, Md. : 1950)
Ogden HL,Lai Y,Nolin JD,An D,Frevert CW,Gelb MH,Altemeier WA,Hallstrand TS
14-0114-82 was used in Flow Cytometry to demonstrate that exogenous and endogenous sPLA2s play an important role in peripheral sensitization, resulting in airway responses to inhaled Ags.
Mon Jun 15 00:00:00 EDT 2020
Wounding Induces Facultative Opn5-Dependent Circadian Photoreception in the Murine Cornea.
Investigative ophthalmology & visual science
Díaz NM,Lang RA,Van Gelder RN,Buhr ED
14-0114 was used in Immunohistochemistry to demonstrate that opsin-dependent direct light sensitivity can be facultatively induced in the murine cornea.
Wed Jun 03 00:00:00 EDT 2020
RIG-I Promotes Cell Death in Hepatocellular Carcinoma by Inducing M1 Polarization of Perineal Macrophages Through the RIG-I/MAVS/NF-κB Pathway.
OncoTargets and therapy
Zhou B,Li C,Yang Y,Wang Z
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Sun Apr 17 00:00:00 EDT 2022
Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells.
Nature communications
Lucas B,White AJ,Cosway EJ,Parnell SM,James KD,Jones ND,Ohigashi I,Takahama Y,Jenkinson WE,Anderson G
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Mon May 04 00:00:00 EDT 2020
Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement.
eLife
Kalinski AL,Yoon C,Huffman LD,Duncker PC,Kohen R,Passino R,Hafner H,Johnson C,Kawaguchi R,Carbajal KS,Jara JS,Hollis E,Geschwind DH,Segal BM,Giger RJ
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Wed Dec 02 00:00:00 EST 2020
CD103+ cDC1 and endogenous CD8+ T cells are necessary for improved CD40L-overexpressing CAR T cell antitumor function.
Nature communications
Kuhn NF,Lopez AV,Li X,Cai W,Daniyan AF,Brentjens RJ
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Wed Dec 02 00:00:00 EST 2020
Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.
JCI insight
Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Thu Aug 20 00:00:00 EDT 2020
Hepatocytes trap and silence coxsackieviruses, protecting against systemic disease in mice.
Communications biology
Kimura T,Flynn CT,Whitton JL
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Oct 16 00:00:00 EDT 2020
CNS Immune Profiling in a Dengue Virus-Infected Immunocompetent Outbred ICR Mice Strain.
Frontiers in cellular and infection microbiology
Shen TJ,Chen CL,Jhan MK,Tseng PC,Lin CF
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Thu Jun 17 00:00:00 EDT 2021
Phenotypical Characterization of Spleen Remodeling in Murine Experimental Visceral Leishmaniasis.
Frontiers in immunology
de Melo CVB,Hermida MD,Mesquita BR,Fontes JLM,Koning JJ,Solcà MDS,Benevides BB,Mota GBS,Freitas LAR,Mebius RE,Dos-Santos WLC
14-0114 was used in Flow cytometry/Cell sorting to emphasize the potential role of spleen remodeling in the control of severe forms of Visceral leishmaniasis (VL) and highlight features potentially involved in this process.
Thu Apr 01 00:00:00 EDT 2021
Novel CD11b+Gr-1+Sca-1+ myeloid cells drive mortality in bacterial infection.
Science advances
Park MY,Kim HS,Lee HY,Zabel BA,Bae YS
14-0114-82 was used in Flow Cytometry to find a previously unidentified pathogenic CD11b+Gr-1+ myeloid cell population that expresses stem cell antigen-1 (Sca-1) induced upon experimental infection with Staphylococcus aureus.
Wed Jan 01 00:00:00 EST 2020
Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity.
Nature communications
Toubal A,Kiaf B,Beaudoin L,Cagninacci L,Rhimi M,Fruchet B,da Silva J,Corbett AJ,Simoni Y,Lantz O,Rossjohn J,McCluskey J,Lesnik P,Maguin E,Lehuen A
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Jul 24 00:00:00 EDT 2020
PGE2 accounts for bidirectional changes in alveolar macrophage self-renewal with aging and smoking.
Life science alliance
Penke LR,Speth JM,Draijer C,Zaslona Z,Chen J,Mancuso P,Freeman CM,Curtis JL,Goldstein DR,Peters-Golden M
14-0114-82 was used in Flow Cytometry to demonstrate that PGE2 functions as a tunable brake on AM numbers under physiologic and pathophysiological conditions.
Sun Nov 01 00:00:00 EDT 2020
Liver Is a Generative Site for the B Cell Response to Ehrlichia muris.
Immunity
Trivedi N,Weisel F,Smita S,Joachim S,Kader M,Radhakrishnan A,Clouser C,Rosenfeld AM,Chikina M,Vigneault F,Hershberg U,Ismail N,Shlomchik MJ
14-0114-82 was used in Flow Cytometry to investigate the nature of liver B cell and spleen response to Ehrlichia muris.
Tue Dec 17 00:00:00 EST 2019
An Nfil3-Zeb2-Id2 pathway imposes Irf8 enhancer switching during cDC1 development.
Nature immunology
Bagadia P,Huang X,Liu TT,Durai V,Grajales-Reyes GE,Nitschké M,Modrusan Z,Granja JM,Satpathy AT,Briseño CG,Gargaro M,Iwata A,Kim S,Chang HY,Shaw AS,Murphy TL,Murphy KM
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Sun Sep 01 00:00:00 EDT 2019
Mechanisms of action of ruxolitinib in murine models of hemophagocytic lymphohistiocytosis.
Blood
Albeituni S,Verbist KC,Tedrick PE,Tillman H,Picarsic J,Bassett R,Nichols KE
14-0114-82 was used in Flow Cytometry to show that ruxolitinib operates through IFN-γ-dependent and -independent mechanisms to dampen HLH by targeting the deleterious effects of T cells and neutrophils, with the latter representing an unappreciated and understudied cell type that contributes to HLH pathogenesis.
Thu Jul 11 00:00:00 EDT 2019
Antigen-presenting ILC3 regulate T cell-dependent IgA responses to colonic mucosal bacteria.
The Journal of experimental medicine
Melo-Gonzalez F,Kammoun H,Evren E,Dutton EE,Papadopoulou M,Bradford BM,Tanes C,Fardus-Reid F,Swann JR,Bittinger K,Mabbott NA,Vallance BA,Willinger T,Withers DR,Hepworth MR
14-0114-82 was used in Flow Cytometry to study the mechanisms that modulate the magnitude and quality of T cell-dependent IgA responses.
Mon Apr 01 00:00:00 EDT 2019
Tissue-Resident Macrophages Promote Renal Cystic Disease.
Journal of the American Society of Nephrology : JASN
Zimmerman KA,Song CJ,Li Z,Lever JM,Crossman DK,Rains A,Aloria EJ,Gonzalez NM,Bassler JR,Zhou J,Crowley MR,Revell DZ,Yan Z,Shan D,Benveniste EN,George JF,Mrug M,Yoder BK
14-0114 was used in Immunohistochemistry-immunofluorescence to investigate the role of resident macrophages during rapid cyst progression in mice.
Tue Oct 01 00:00:00 EDT 2019
IL-33 drives influenza-induced asthma exacerbations by halting innate and adaptive antiviral immunity.
The Journal of allergy and clinical immunology
Ravanetti L,Dijkhuis A,Dekker T,Sabogal Pineros YS,Ravi A,Dierdorp BS,Erjefält JS,Mori M,Pavlidis S,Adcock IM,Rao NL,Lutter R
14-0114-82 was used in Flow Cytometry to show that IL-33 drives this increased airway hyperresponsiveness and viral replication and that both lymphoid and myeloid populations infiltrate into the airway lumen and parenchyma, whereas thymic stromal lymphopoietin was redundant in this model.
Mon Apr 01 00:00:00 EDT 2019
Inhibition of T cell activation and function by the adaptor protein CIN85.
Science signaling
Kong MS,Hashimoto-Tane A,Kawashima Y,Sakuma M,Yokosuka T,Kometani K,Onishi R,Carpino N,Ohara O,Kurosaki T,Phua KK,Saito T
14-0114-82 was used in Flow Cytometry to show that CIN85 (Cbl-interacting protein of 85 kDa) limited T cell responses to T cell receptor stimulation.
Tue Feb 05 00:00:00 EST 2019
CD1d highly expressed on DCs reduces lung tumor burden by enhancing antitumor immunity.
Oncology reports
Li Y,Zhao C,Liu J,Lu Z,Lu M,Gu J,Liu R
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Wed May 01 00:00:00 EDT 2019
Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells.
Frontiers in immunology
Xu J,Pei S,Wang Y,Liu J,Qian Y,Huang M,Zhang Y,Xiao Y
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Wed Oct 14 00:00:00 EDT 2020
Knockdown of Ant2 Reduces Adipocyte Hypoxia And Improves Insulin Resistance in Obesity.
Nature metabolism
Seo JB,Riopel M,Cabrales P,Huh JY,Bandyopadhyay GK,Andreyev AY,Murphy AN,Beeman SC,Smith GI,Klein S,Lee YS,Olefsky JM
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2019
Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population.
Cell reports
Leylek R,Alcántara-Hernández M,Lanzar Z,Lüdtke A,Perez OA,Reizis B,Idoyaga J
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Tue Dec 10 00:00:00 EST 2019
Early Transcriptional Signature in Dendritic Cells and the Induction of Protective T Cell Responses Upon Immunization With VLPs Containing TLR Ligands-A Role for CCL2.
Frontiers in immunology
Gomes AC,Mohsen MO,Mueller JE,Leoratti FMS,Cabral-Miranda G,Bachmann MF
14-0114 was used in Flow cytometry/Cell sorting to use virus-like particles(VLPs) associated to Toll-like receptor(TLR) ligands as tools to modulate cytotoxic response mediated by CD8+ T cells and provide further insight in the development of T cell-based immunotherapy.
Tue Oct 13 00:00:00 EDT 2020
Sequential Sensing by TLR2 and Mincle Directs Immature Myeloid Cells to Protect against Invasive Group A Streptococcal Infection in Mice.
Cell reports
Matsumura T,Ikebe T,Arikawa K,Hosokawa M,Aiko M,Iguchi A,Togashi I,Kai S,Ohara S,Ohara N,Ohnishi M,Watanabe H,Kobayashi K,Takeyama H,Yamasaki S,Takahashi Y,Ato M
14-0114-82 was used in Flow Cytometry to show IFN-γ-producing immature myeloid cells can provide protection to mice in invasive group A Streptococcus infection.
Tue Apr 09 00:00:00 EDT 2019
Discrete viral E2 lysine residues and scavenger receptor MARCO are required for clearance of circulating alphaviruses.
eLife
Carpentier KS,Davenport BJ,Haist KC,McCarthy MK,May NA,Robison A,Ruckert C,Ebel GD,Morrison TE
14-0114-82 was used in Flow Cytometry to reveal a previously unrecognized innate immune pathway that controls alphavirus viremia and dissemination in vertebrate hosts, ultimately influencing disease severity and likely transmission efficiency.
Wed Oct 09 00:00:00 EDT 2019
Immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy to eradicate colorectal tumors.
Nature communications
Duan X,Chan C,Han W,Guo N,Weichselbaum RR,Lin W
14-0114 was used in Flow cytometry/Cell sorting to conclude that the intrinsically biodegradable, well tolerated, and systemically available immunostimulatory NCP promises to enter clinical testing as an immunotherapy against colorectal cancer.
Tue Apr 23 00:00:00 EDT 2019
Female and male mouse lung group 2 innate lymphoid cells differ in gene expression profiles and cytokine production.
PloS one
Mathä L,Shim H,Steer CA,Yin YH,Martinez-Gonzalez I,Takei F
14-0114-82 was used in Flow Cytometry to suggest that female ILC2s are more readily activated than male ILC2s due to their gene expression at the naïve state, which is potentially influenced by the lung environment.
Mon Dec 16 00:00:00 EST 2019
Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells.
Nature
Garaycoechea JI,Crossan GP,Langevin F,Mulderrig L,Louzada S,Yang F,Guilbaud G,Park N,Roerink S,Nik-Zainal S,Stratton MR,Patel KJ
14-0114 was used in Flow cytometry/Cell sorting to identify how the choice of DNA-repair pathway and a stringent p53 response limit the transmission of aldehyde-induced mutations in stem cells.
Thu Jan 11 00:00:00 EST 2018
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control.
Cell
Böttcher JP,Bonavita E,Chakravarty P,Blees H,Cabeza-Cabrerizo M,Sammicheli S,Rogers NC,Sahai E,Zelenay S,Reis e Sousa C
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Thu Feb 22 00:00:00 EST 2018
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Thu Jun 28 00:00:00 EDT 2018
A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy.
Cell research
Du X,Tang F,Liu M,Su J,Zhang Y,Wu W,Devenport M,Lazarski CA,Zhang P,Wang X,Ye P,Wang C,Hwang E,Zhu T,Xu T,Zheng P,Liu Y
14-0114 was used in in vitro experiments to show that at high concentrations, the anti-CTLA-4 antibody Ipilimumab blocks neither B7 trans-endocytosis by CTLA-4 nor CTLA-4 binding to immobilized or cell-associated B7.
Sun Apr 01 00:00:00 EDT 2018
Insulin resistance causes inflammation in adipose tissue.
The Journal of clinical investigation
Shimobayashi M,Albert V,Woelnerhanssen B,Frei IC,Weissenberger D,Meyer-Gerspach AC,Clement N,Moes S,Colombi M,Meier JA,Swierczynska MM,Jenö P,Beglinger C,Peterli R,Hall MN
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Mon Apr 02 00:00:00 EDT 2018
Granulocyte-CSF links destructive inflammation and comorbidities in obstructive lung disease.
The Journal of clinical investigation
Tsantikos E,Lau M,Castelino CM,Maxwell MJ,Passey SL,Hansen MJ,McGregor NE,Sims NA,Steinfort DP,Irving LB,Anderson GP,Hibbs ML
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Jun 01 00:00:00 EDT 2018
Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival.
The Journal of clinical investigation
Bahmani B,Uehara M,Jiang L,Ordikhani F,Banouni N,Ichimura T,Solhjou Z,Furtmüller GJ,Brandacher G,Alvarez D,von Andrian UH,Uchimura K,Xu Q,Vohra I,Yilmam OA,Haik Y,Azzi J,Kasinath V,Bromberg JS,McGrath MM,Abdi R
14-0114 was used in Immunohistochemistry to synthesize a nanoparticle (NP) as a carrier of anti-CD3, and optimized the conjugation strategy to coat the NP surface with MECA79 mAb (MECA79-anti-CD3-NP) to enhance LN accumulation.
Thu Nov 01 00:00:00 EDT 2018
The E3 ligase VHL controls alveolar macrophage function via metabolic-epigenetic regulation.
The Journal of experimental medicine
Zhang W,Li Q,Li D,Li J,Aki D,Liu YC
14-0114 was used in Flow cytometry/Cell sorting to show VHL regulates alveolar macrophages and acts as a crucial egulatory factor in lung inflammation and fibrosis.
Mon Dec 03 00:00:00 EST 2018
Continuous activity of Foxo1 is required to prevent anergy and maintain the memory state of CD8+ T cells.
The Journal of experimental medicine
Delpoux A,Michelini RH,Verma S,Lai CY,Omilusik KD,Utzschneider DT,Redwood AJ,Goldrath AW,Benedict CA,Hedrick SM
14-0114 was used in Flow cytometry/Cell sorting to show that FOXO1 is continuously required for all the phenotypic characteristics of memory-effector T cells.
Mon Feb 05 00:00:00 EST 2018
Personalized Tumor RNA Loaded Lipid-Nanoparticles Prime the Systemic and Intratumoral Milieu for Response to Cancer Immunotherapy.
Nano letters
Sayour EJ,Grippin A,De Leon G,Stover B,Rahman M,Karachi A,Wummer B,Moore G,Castillo-Caro P,Fredenburg K,Sarkisian MR,Huang J,Deleyrolle LP,Sahay B,Carrera-Justiz S,Mendez-Gomez HR,Mitchell DA
14-0114 was used in Immunohistochemistry to demonstrate that widespread immune activation from tumour loaded RNA-NPs concomitant with inducible PD-L1 expression can be therapeutically exploited in cancer immunotherapy.
Wed Oct 10 00:00:00 EDT 2018
Integrin β1 Optimizes Diabetogenic T Cell Migration and Function in the Pancreas.
Frontiers in immunology
Espinosa-Carrasco G,Le Saout C,Fontanaud P,Michau A,Mollard P,Hernandez J,Schaeffer M
14-0114 was used in Immunohistochemistry-immunofluorescence to study the tissue-dependent mechanisms controlling effector T cell motility.
Fri Aug 16 00:00:00 EDT 2019
Cleavage of TL1A Differentially Regulates Its Effects on Innate and Adaptive Immune Cells.
Journal of immunology (Baltimore, Md. : 1950)
Ferdinand JR,Richard AC,Meylan F,Al-Shamkhani A,Siegel RM
14-0114 was used in Flow cytometry/Cell sorting to suggest differential roles for membrane and soluble TL1A on adaptive and innate immune cells and have implications for the consequences of blocking these two forms of TL1A.
Thu Feb 15 00:00:00 EST 2018
Photodynamic therapy reduces the inhibitory effect of osteosarcoma cells on dendritic cells by upregulating HSP70.
Oncology letters
Zhang F,Zhu Y,Fan G,Hu S
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2018
FACS isolation of live mouse eosinophils at high purity via a protocol that does not target Siglec F.
Journal of immunological methods
Geslewitz WE,Percopo CM,Rosenberg HF
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2018
Macrophage Depletion Protects against Cigarette Smoke-Induced Inflammatory Response in the Mouse Colon and Lung.
Frontiers in physiology
Lim D,Kim W,Lee C,Bae H,Kim J
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Wed Sep 30 00:00:00 EDT 2020
Characterization of Multiple Cytokine Combinations and TGF-β on Differentiation and Functions of Myeloid-Derived Suppressor Cells.
International journal of molecular sciences
Lee CR,Lee W,Cho SK,Park SG
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Thu Mar 15 00:00:00 EDT 2018
Primary Lung Dendritic Cell Cultures to Assess Efficacy of Spectinamide-1599 Against Intracellular Mycobacterium tuberculosis.
Frontiers in microbiology
Santos K,Lukka PB,Grzegorzewicz A,Jackson M,Trivedi A,Pavan F,Chorilli M,Braunstein M,Hickey A,Meibohm B,Gonzalez-Juarrero M
14-0114 was used in Flow cytometry/Cell sorting to demonstrate that monotherapy with either spectinamide-1599 or pyrazinamide can reduce the intracellular bacterial burden by more than 99.9%.
Thu Oct 01 00:00:00 EDT 2020
CCL7 Is a Negative Regulator of Cutaneous Inflammation Following Leishmania major Infection.
Frontiers in immunology
Ford J,Hughson A,Lim K,Bardina SV,Lu W,Charo IF,Lim JK,Fowell DJ
14-0114 was used in Flow cytometry/Cell sorting to determine the role of CCL7 in Leishmania major infection.
Mon Oct 21 00:00:00 EDT 2019
Early cellular interactions and immune transcriptome profiles in human factor VIII-exposed hemophilia A mice.
Journal of thrombosis and haemostasis : JTH
Lai JD,Cartier D,Hartholt RB,Swystun LL,van Velzen AS,den Haan JMM,Hough C,Voorberg J,Lillicrap D
14-0114 was used in Immunohistochemistry to assess cellular interactions and expression profiles in hemophilia A mice.
Thu Mar 01 00:00:00 EST 2018
Rapid clearance of heavy chain-modified hyaluronan during resolving acute lung injury.
Respiratory research
Ni K,Gill A,Tseng V,Mikosz AM,Koike K,Beatman EL,Xu CY,Cao D,Gally F,Mould KJ,Serban KA,Schweitzer KS,March KL,Janssen WJ,Nozik-Grayck E,Garantziotis S,Petrache I
14-0114 was used in Flow cytometry/Cell sorting to show the covalent HC-HA binding, which is exclusively mediated by tumor necrosis factor α (TNFα)-stimulated-gene-6 (TSG-6), may play an important role in the onset or the resolution of lung inflammation in acute lung injury (ALI) induced by respiratory infection.
Thu May 31 00:00:00 EDT 2018
Ozanimod (RPC1063), a selective S1PR1 and S1PR5 modulator, reduces chronic inflammation and alleviates kidney pathology in murine systemic lupus erythematosus.
PloS one
Taylor Meadows KR,Steinberg MW,Clemons B,Stokes ME,Opiteck GJ,Peach R,Scott FL
14-0114 was used in Flow cytometry/Cell sorting to show RP-101075 lowered the number of plasmacytoid dendritic cells, a major source of interferon alpha in lupus patients, and reduced all B and T cell subsets in the spleen.
Wed Jul 18 00:00:00 EDT 2018
Bispecific antibody targets multiple Pseudomonas aeruginosa evasion mechanisms in the lung vasculature.
The Journal of clinical investigation
Thanabalasuriar A,Surewaard BG,Willson ME,Neupane AS,Stover CK,Warrener P,Wilson G,Keller AE,Sellman BR,DiGiandomenico A,Kubes P
14-0114 was used in Flow cytometry/Cell sorting to highlight the need to block multiple evasion and subversion mechanisms in tandem to kill P. aeruginosa.
Thu Jun 01 00:00:00 EDT 2017
Combined antiangiogenic and anti-PD-L1 therapy stimulates tumor immunity through HEV formation.
Science translational medicine
Allen E,Jabouille A,Rivera LB,Lodewijckx I,Missiaen R,Steri V,Feyen K,Tawney J,Hanahan D,Michael IP,Bergers G
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunofluorescence
Wed Apr 12 00:00:00 EDT 2017
Mast cells acquire MHCII from dendritic cells during skin inflammation.
The Journal of experimental medicine
Dudeck J,Medyukhina A,Fröbel J,Svensson CM,Kotrba J,Gerlach M,Gradtke AC,Schröder B,Speier S,Figge MT,Dudeck A
14-0114 was used in Flow cytometry/Cell sorting to identify an innate intercellular communication arming resident mast cells with key dendritic cell(DC) functions that might contribute to the acute defence potential during critical periods of migration-based DC absence.
Mon Dec 04 00:00:00 EST 2017
RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease.
EMBO molecular medicine
Zhu H,Lou F,Yin Q,Gao Y,Sun Y,Bai J,Xu Z,Liu Z,Cai W,Ke F,Zhang L,Zhou H,Wang H,Wang G,Chen X,Zhang H,Wang Z,Ginhoux F,Lu C,Su B,Wang H
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
Continual renewal and replication of persistent Leishmania major parasites in concomitantly immune hosts.
Proceedings of the National Academy of Sciences of the United States of America
Mandell MA,Beverley SM
14-0114 was used in Flow cytometry/Cell sorting to investigate whether persistent parasites undergo replication.
Tue Jan 31 00:00:00 EST 2017
Mitogenic stimulation accelerates influenza-induced mortality by increasing susceptibility of alveolar type II cells to infection.
Proceedings of the National Academy of Sciences of the United States of America
Nikolaidis NM,Noel JG,Pitstick LB,Gardner JC,Uehara Y,Wu H,Saito A,Lewnard KE,Liu H,White MR,Hartshorn KL,McCormack FX
14-0114 was used in Flow cytometry/Cell sorting to investigate the role of mitogenic stimulation in susceptibility to pneumonia.
Tue Aug 08 00:00:00 EDT 2017
FcεRI γ-Chain Negatively Modulates Dectin-1 Responses in Dendritic Cells.
Frontiers in immunology
Pan YG,Yu YL,Lin CC,Lanier LL,Chu CL
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
CD4+ T Helper Cells Play a Key Role in Maintaining Diabetogenic CD8+ T Cell Function in the Pancreas.
Frontiers in immunology
Espinosa-Carrasco G,Le Saout C,Fontanaud P,Stratmann T,Mollard P,Schaeffer M,Hernandez J
14-0114 was used in Immunohistochemistry to provide novel insight in the cellular mechanisms regulating effector T cell functionality in peripheral tissues with important implications for immunotherapies.
Wed Nov 20 00:00:00 EST 2019
Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation.
The Journal of cell biology
Vander Lugt B,Riddell J,Khan AA,Hackney JA,Lesch J,DeVoss J,Weirauch MT,Singh H,Mellman I
14-0114 was used in Flow cytometry/Cell sorting to study how DCs modulate their ability to prime tolerogenic or immunogenic T cells by expressing a core antigen presentation module that is overlaid by distinctive regulatory modules to promote either tolerance or immunity.
Mon Mar 06 00:00:00 EST 2017
Early IL-6 signalling promotes IL-27 dependent maturation of regulatory T cells in the lungs and resolution of viral immunopathology.
PLoS pathogens
Pyle CJ,Uwadiae FI,Swieboda DP,Harker JA
14-0114-82 was used in Flow Cytometry to show that during respiratory virus infection the prototypic inflammatory cytokine IL-6 is a critical anti-inflammatory regulator of viral induced immunopathology in the respiratory tract through its induction of IL-27.
Fri Sep 01 00:00:00 EDT 2017
NCR1-deficiency diminishes the generation of protective murine cytomegalovirus antibodies by limiting follicular helper T-cell maturation.
European journal of immunology
Miletic A,Lenartic M,Popovic B,Brizic I,Trsan T,Miklic K,Mandelboim O,Krmpotic A,Jonjic S
14-0114 was used in Flow cytometry/Cell sorting to provide evidence for the role of NCR1 in antibody response to mouse cytomegalovirus infection.
Fri Sep 01 00:00:00 EDT 2017
Increased White Matter Inflammation in Aging- and Alzheimer's Disease Brain.
Frontiers in molecular neuroscience
Raj D,Yin Z,Breur M,Doorduin J,Holtman IR,Olah M,Mantingh-Otter IJ,Van Dam D,De Deyn PP,den Dunnen W,Eggen BJL,Amor S,Boddeke E
14-0114 was used in Immunohistochemistry to indicate that microglia-induced neuroinflammation is predominant in the white matter of aging mice and humans as well as in EOAD brains.
Thu Oct 01 00:00:00 EDT 2020
Cornea lymphatics drive the CD8+ T-cell response to herpes simplex virus-1.
Immunology and cell biology
Gurung HR,Carr MM,Carr DJ
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
Identification of different macrophage subpopulations with distinct activities in a mouse model of oxygen-induced retinopathy.
International journal of molecular medicine
Zhu Y,Zhang L,Lu Q,Gao Y,Cai Y,Sui A,Su T,Shen X,Xie B
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunofluorescence
Tue Aug 01 00:00:00 EDT 2017
Discrimination of the heterogeneity of bone marrow‑derived dendritic cells.
Molecular medicine reports
Wang J,Dai X,Hsu C,Ming C,He Y,Zhang J,Wei L,Zhou P,Wang CY,Yang J,Gong N
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Wed Nov 01 00:00:00 EDT 2017
The Second-Generation PGI2 Analogue Treprostinil Fails to Chemoprevent Tumors in a Murine Lung Adenocarcinoma Model.
Cancer prevention research (Philadelphia, Pa.)
Dwyer-Nield L,Hickey GA,Friedman M,Choo K,McArthur DG,Tennis MA,New ML,Geraci M,Keith RL
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Wed Nov 01 00:00:00 EDT 2017
Calreticulin is an effective immunologic adjuvant to tumor-associated antigens.
Experimental and therapeutic medicine
Wang J,Gao ZP,Qin S,Liu CB,Zou LL
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy.
Scientific reports
Gao S,Li C,Zhu Y,Wang Y,Sui A,Zhong Y,Xie B,Shen X
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Feb 17 00:00:00 EST 2017
PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy.
Scientific reports
Gao S,Li C,Zhu Y,Wang Y,Sui A,Zhong Y,Xie B,Shen X
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Feb 17 00:00:00 EST 2017
CD11c+ resident macrophages drive hepatocyte death-triggered liver fibrosis in a murine model of nonalcoholic steatohepatitis.
JCI insight
Itoh M,Suganami T,Kato H,Kanai S,Shirakawa I,Sakai T,Goto T,Asakawa M,Hidaka I,Sakugawa H,Ohnishi K,Komohara Y,Asano K,Sakaida I,Tanaka M,Ogawa Y
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunohistochemistry
Thu Nov 16 00:00:00 EST 2017
CD11c+ resident macrophages drive hepatocyte death-triggered liver fibrosis in a murine model of nonalcoholic steatohepatitis.
JCI insight
Itoh M,Suganami T,Kato H,Kanai S,Shirakawa I,Sakai T,Goto T,Asakawa M,Hidaka I,Sakugawa H,Ohnishi K,Komohara Y,Asano K,Sakaida I,Tanaka M,Ogawa Y
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunohistochemistry
Thu Nov 16 00:00:00 EST 2017
Precision-cut Mouse Lung Slices to Visualize Live Pulmonary Dendritic Cells.
Journal of visualized experiments : JoVE
Lyons-Cohen MR,Thomas SY,Cook DN,Nakano H
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunofluorescence
Wed Apr 05 00:00:00 EDT 2017
BEX1 is an RNA-dependent mediator of cardiomyopathy.
Nature communications
Accornero F,Schips TG,Petrosino JM,Gu SQ,Kanisicak O,van Berlo JH,Molkentin JD
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Thu Nov 30 00:00:00 EST 2017
Commensal microbiota maintains alveolar macrophages with a low level of CCL24 production to generate anti-metastatic tumor activity.
Scientific reports
Cheng M,Chen Y,Wang L,Chen W,Yang L,Shen G,Xu T,Shen G,Tian Z,Hu S
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Mon Aug 07 00:00:00 EDT 2017
Alternative activation generates IL-10 producing type 2 innate lymphoid cells.
Nature communications
Seehus CR,Kadavallore A,Torre B,Yeckes AR,Wang Y,Tang J,Kaye J
14-0114 was used in Flow Cytometry to demonstrate the generation of a previously unappreciated IL-10 producing type 2 innate lymphoid cell effector cell population.
Fri Dec 01 00:00:00 EST 2017
Indole-3-carbinol, a plant nutrient and AhR-Ligand precursor, supports oral tolerance against OVA and improves peanut allergy symptoms in mice.
PloS one
Hammerschmidt-Kamper C,Biljes D,Merches K,Steiner I,Daldrup T,Bol-Schoenmakers M,Pieters RHH,Esser C
14-0114 was used in Flow cytometry/Cell sorting to determine whether a common plant-derived, dietary aryl hydrocarbon receptor-ligand modulates oral tolerance.
Fri Oct 06 00:00:00 EDT 2017
Functional characterization of the lysosomal membrane protein TMEM192 in mice.
Oncotarget
Nguyen TL,Schneppenheim J,Rudnik S,Lüllmann-Rauch R,Bernreuther C,Hermans-Borgmeyer I,Glatzel M,Saftig P,Schröder B
14-0114-82 was used in Flow Cytometry to conclude that under basal conditions in vivo the loss of TMEM192 can be efficiently compensated by alternative pathways.
Tue Jul 04 00:00:00 EDT 2017
High fat diet exacerbates murine psoriatic dermatitis by increasing the number of IL-17-producing γδ T cells.
Scientific reports
Nakamizo S,Honda T,Adachi A,Nagatake T,Kunisawa J,Kitoh A,Otsuka A,Dainichi T,Nomura T,Ginhoux F,Ikuta K,Egawa G,Kabashima K
14-0114 was used in Flow cytometry/Cell sorting to indicate that HFD is a key element in exacerbation of IMQ-induced psoriatic dermatitis, and further raise the possibility of HFD as a factor that links obesity and psoriasis.
Thu Oct 26 00:00:00 EDT 2017
Identification of apoB-100 Peptide-Specific CD8+ T Cells in Atherosclerosis.
Journal of the American Heart Association
Dimayuga PC,Zhao X,Yano J,Lio WM,Zhou J,Mihailovic PM,Cercek B,Shah PK,Chyu KY
14-0114-82 was used in Flow Cytometry to identify and characterize endogenous, antigenspecific CD8+ T cells in atherosclerosis.
Sat Jul 15 00:00:00 EDT 2017
WASH maintains NKp46+ ILC3 cells by promoting AHR expression.
Nature communications
Xia P,Liu J,Wang S,Ye B,Du Y,Xiong Z,Han ZG,Tong L,Fan Z
14-0114 was used in Flow cytometry/Cell sorting to study how WASH-mediated AHR expression has a critical function in the maintenance of NKp46(+) ILC3s.
Wed Jun 07 00:00:00 EDT 2017
Human and Mouse Hematopoietic Stem Cells Are a Depot for Dormant Mycobacterium tuberculosis.
PloS one
Tornack J,Reece ST,Bauer WM,Vogelzang A,Bandermann S,Zedler U,Stingl G,Kaufmann SH,Melchers F
14-0114-82 was used in Flow Cytometry to conclude that LT-pHSCs, together with MSCs of Mtb-infected humans and mice serve as a hitherto unappreciated quiescent cellular depot for Mtb during latent TB infection.
Tue Sep 05 00:00:00 EDT 2017
Heavy Chain-Hyaluronan/Pentraxin 3 from Amniotic Membrane Suppresses Inflammation and Scarring in Murine Lacrimal Gland and Conjunctiva of Chronic Graft-versus-Host Disease.
Scientific reports
Ogawa Y,He H,Mukai S,Imada T,Nakamura S,Su CW,Mahabole M,Tseng SC,Tsubota K
14-0114 was used in Western Blotting to help prove the concept that subcutaneous and subconjunctival injection of HC-HA/PTX3 is a novel approach to prevent dry eye disease caused by cGVHD.
Mon Feb 06 00:00:00 EST 2017
Advax, a Delta Inulin Microparticle, Potentiates In-built Adjuvant Property of Co-administered Vaccines.
EBioMedicine
Hayashi M,Aoshi T,Haseda Y,Kobiyama K,Wijaya E,Nakatsu N,Igarashi Y,Standley DM,Yamada H,Honda-Okubo Y,Hara H,Saito T,Takai T,Coban C,Petrovsky N,Ishii KJ
14-0114 was used in Flow cytometry/Cell sorting to study the immunological characteristics and mechanism of action of delta inulin-derived microparticle Advax.
Wed Feb 01 00:00:00 EST 2017
Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.
Cell
Chudnovskiy A,Mortha A,Kana V,Kennard A,Ramirez JD,Rahman A,Remark R,Mogno I,Ng R,Gnjatic S,Amir ED,Solovyov A,Greenbaum B,Clemente J,Faith J,Belkaid Y,Grigg ME,Merad M
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Thu Oct 06 00:00:00 EDT 2016
Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation.
Nature immunology
Monticelli LA,Buck MD,Flamar AL,Saenz SA,Tait Wojno ED,Yudanin NA,Osborne LC,Hepworth MR,Tran SV,Rodewald HR,Shah H,Cross JR,Diamond JM,Cantu E,Christie JD,Pearce EL,Artis D
14-0114 was used in Flow cytometry/Cell sorting to identify Arg1 as a key regulator of group 2 innate lymphoid cell bioenergetics that control proliferative capacity and pro-inflammatory functions.
Wed Jun 01 00:00:00 EDT 2016
Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure.
Circulation research
Sager HB,Hulsmans M,Lavine KJ,Moreira MB,Heidt T,Courties G,Sun Y,Iwamoto Y,Tricot B,Khan OF,Dahlman JE,Borodovsky A,Fitzgerald K,Anderson DG,Weissleder R,Libby P,Swirski FK,Nahrendorf M
14-0114 was used in Flow cytometry/Cell sorting to elucidate the origin and roles of macrophages in the post-myocardial infarction remodelling of nonischaemic remote myocardium.
Fri Sep 16 00:00:00 EDT 2016
Loss of gastrokine-2 drives premalignant gastric inflammation and tumor progression.
The Journal of clinical investigation
Menheniott TR,O'Connor L,Chionh YT,Däbritz J,Scurr M,Rollo BN,Ng GZ,Jacobs S,Catubig A,Kurklu B,Mercer S,Minamoto T,Ong DE,Ferrero RL,Fox JG,Wang TC,Sutton P,Judd LM,Giraud AS
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2016
Migratory CD103+ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12.
The Journal of experimental medicine
Everts B,Tussiwand R,Dreesen L,Fairfax KC,Huang SC,Smith AM,O'Neill CM,Lam WY,Edelson BT,Urban JF,Murphy KM,Pearce EJ
14-0114 was used in Flow cytometry/Cell sorting to investigate the role of CD8α+ and CD103+ dendritic cells in suppressing helminth-driven type 2 immune responses.
Mon Jan 11 00:00:00 EST 2016
Dysbiosis-induced IL-33 contributes to impaired antiviral immunity in the genital mucosa.
Proceedings of the National Academy of Sciences of the United States of America
Oh JE,Kim BC,Chang DH,Kwon M,Lee SY,Kang D,Kim JY,Hwang I,Yu JW,Nakae S,Lee HK
14-0114 was used in Flow cytometry/Cell sorting to provide insight into the mechanisms of homeostasis maintained by commensal bacteria, and reveal a deleterious consequence of dysbiosis in antiviral immune defense.
Tue Feb 09 00:00:00 EST 2016
Protective Role for B-1b B Cells and IgM in Obesity-Associated Inflammation, Glucose Intolerance, and Insulin Resistance.
Arteriosclerosis, thrombosis, and vascular biology
Harmon DB,Srikakulapu P,Kaplan JL,Oldham SN,McSkimming C,Garmey JC,Perry HM,Kirby JL,Prohaska TA,Gonen A,Hallowell P,Schirmer B,Tsimikas S,Taylor AM,Witztum JL,McNamara CA
14-0114 was used in Flow cytometry/Cell sorting to investigate the role of B-cell functions in obesity-induced metabolic dysfunction.
Fri Apr 01 00:00:00 EDT 2016
CD11c(+) monocyte/macrophages promote chronic Helicobacter hepaticus-induced intestinal inflammation through the production of IL-23.
Mucosal immunology
Arnold IC,Mathisen S,Schulthess J,Danne C,Hegazy AN,Powrie F
14-0114 was used in Flow cytometry/Cell sorting to investigate the mechanism by which IL-23 produced by CD11c+ monocytes/macrophages promotes chronic Helicobacter hepaticus-induced intestinal inflammation.
Tue Mar 01 00:00:00 EST 2016
Survival and Functionality of Human Induced Pluripotent Stem Cell-Derived Oligodendrocytes in a Nonhuman Primate Model for Multiple Sclerosis.
Stem cells translational medicine
Thiruvalluvan A,Czepiel M,Kap YA,Mantingh-Otter I,Vainchtein I,Kuipers J,Bijlard M,Baron W,Giepmans B,Brück W,'t Hart BA,Boddeke E,Copray S
14-0114 was used in Immunohistochemistry to study the use of human induced pluripotent stem cell-derived oligodendrocyte precursor cells in a nonhuman primate model of progressive multiple sclerosis.
Tue Nov 01 00:00:00 EDT 2016
IL-33-Dependent Group 2 Innate Lymphoid Cells Promote Cutaneous Wound Healing.
The Journal of investigative dermatology
Rak GD,Osborne LC,Siracusa MC,Kim BS,Wang K,Bayat A,Artis D,Volk SW
14-0114 was used in Flow cytometry/Cell sorting to demonstrate that cutaneous injury promotes an IL-33-dependent group 2 ILC (ILC2) response and that abrogation of this response can impair efficient wound closure.
Mon Feb 01 00:00:00 EST 2016
IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid.
PLoS pathogens
Naujoks J,Tabeling C,Dill BD,Hoffmann C,Brown AS,Kunze M,Kempa S,Peter A,Mollenkopf HJ,Dorhoi A,Kershaw O,Gruber AD,Sander LE,Witzenrath M,Herold S,Nerlich A,Hocke AC,van Driel I,Suttorp N,Bedoui S,Hilbi H,Trost M,Opitz B
14-0114 was used in Flow cytometry/Cell sorting to explore the overall role IFNs play in inducing substantial remodeling of bacterial vacuoles and in stimulating production of IRG1-derived itaconic acid which targets intravacuolar pathogens.
Mon Feb 01 00:00:00 EST 2016
An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens.
PLoS pathogens
Meliopoulos VA,Van de Velde LA,Van de Velde NC,Karlsson EA,Neale G,Vogel P,Guy C,Sharma S,Duan S,Surman SL,Jones BG,Johnson MD,Bosio C,Jolly L,Jenkins RG,Hurwitz JL,Rosch JW,Sheppard D,Thomas PG,Murray PJ,Schultz-Cherry S
14-0114 was used in Immunohistochemistry to show that upregulation of the epithelial integrin αVβ6 during influenza infection is involved in disease pathogenesis.
Mon Aug 01 00:00:00 EDT 2016
A20 Deficiency in Lung Epithelial Cells Protects against Influenza A Virus Infection.
PLoS pathogens
Maelfait J,Roose K,Vereecke L,Mc Guire C,Sze M,Schuijs MJ,Willart M,Ibañez LI,Hammad H,Lambrecht BN,Beyaert R,Saelens X,van Loo G
14-0114 was used in Flow cytometry/Cell sorting to investigate the function of A20 in club cells in antiviral immunity, showing that deficiency in A20 protects against influenza virus infection.
Fri Jan 01 00:00:00 EST 2016
Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity.
PLoS pathogens
Nice TJ,Osborne LC,Tomov VT,Artis D,Wherry EJ,Virgin HW
14-0114 was used in Flow cytometry/Cell sorting to study type I interferon signalling in dendritic cells during Murine norovirus infection.
Wed Jun 01 00:00:00 EDT 2016
Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.
Immunology
Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Sat Oct 01 00:00:00 EDT 2016
Identification of a Hematopoietic Cell Dedifferentiation-Inducing Factor.
Journal of cellular physiology
Li Y,Adomat H,Guns ET,Hojabrpour P,Duronio V,Curran TA,Jalili RB,Jia W,Delwar Z,Zhang Y,Elizei SS,Ghahary A
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunocytochemistry
Wed Jun 01 00:00:00 EDT 2016
TNF and CD28 Signaling Play Unique but Complementary Roles in the Systemic Recruitment of Innate Immune Cells after Staphylococcus aureus Enterotoxin A Inhalation.
Journal of immunology (Baltimore, Md. : 1950)
Svedova J,Tsurutani N,Liu W,Khanna KM,Vella AT
14-0114 was used in Flow cytometry/Cell sorting to investigate how Staphylococcus aureus enterotoxins spread systemically and trigger inflammatory cascades.
Wed Jun 01 00:00:00 EDT 2016
T Cell Priming by Activated Nlrc5-Deficient Dendritic Cells Is Unaffected despite Partially Reduced MHC Class I Levels.
Journal of immunology (Baltimore, Md. : 1950)
Rota G,Ludigs K,Siegert S,Tardivel A,Morgado L,Reith W,De Gassart A,Guarda G
14-0114 was used in Flow cytometry/Cell sorting to show that Nlrc5 deficiency is not sufficient to hinder T cell activation, highlighting the robustness of the T cell priming process by activated dendritic cells.
Fri Apr 01 00:00:00 EDT 2016
Semaphorin 7A Promotes Chemokine-Driven Dendritic Cell Migration.
Journal of immunology (Baltimore, Md. : 1950)
van Rijn A,Paulis L,te Riet J,Vasaturo A,Reinieren-Beeren I,van der Schaaf A,Kuipers AJ,Schulte LP,Jongbloets BC,Pasterkamp RJ,Figdor CG,van Spriel AB,Buschow SI
14-0114 was used in Immunohistochemistry on frozen tissues to define the molecules that induce the migratory phenotype of dendritic cells.
Fri Jan 01 00:00:00 EST 2016
Semaphorin 7A Promotes Chemokine-Driven Dendritic Cell Migration.
Journal of immunology (Baltimore, Md. : 1950)
van Rijn A,Paulis L,te Riet J,Vasaturo A,Reinieren-Beeren I,van der Schaaf A,Kuipers AJ,Schulte LP,Jongbloets BC,Pasterkamp RJ,Figdor CG,van Spriel AB,Buschow SI
14-0114 was used in Immunohistochemistry on frozen tissues to define the molecules that induce the migratory phenotype of dendritic cells.
Fri Jan 01 00:00:00 EST 2016
Blood Stem Cell Activity Is Arrested by Th1-Mediated Injury Preventing Engraftment following Nonmyeloablative Conditioning.
Journal of immunology (Baltimore, Md. : 1950)
Müller AM,Florek M,Kohrt HE,Küpper NJ,Filatenkov A,Linderman JA,Hadeiba H,Negrin RS,Shizuru JA
14-0114 was used in Flow cytometry/Cell sorting to shed new light on the effects of CD4+ T cells on HSC biology.
Tue Nov 15 00:00:00 EST 2016
Comparison of RELMα and RELMβ Single- and Double-Gene-Deficient Mice Reveals that RELMα Expression Dictates Inflammation and Worm Expulsion in Hookworm Infection.
Infection and immunity
Chen G,Wang SH,Jang JC,Odegaard JI,Nair MG
14-0114 was used in Flow cytometry/Cell sorting to delineate the function of two resistin-like molecules, RELMα and RELMβ, following infection with hookworm.
Fri Apr 01 00:00:00 EDT 2016
Age-dependent divergent effects of OX40L treatment on the development of diabetes in NOD mice.
Autoimmunity
Haddad CS,Bhattacharya P,Alharshawi K,Marinelarena A,Kumar P,El-Sayed O,Elshabrawy HA,Epstein AL,Prabhakar BS
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
CD80 and CD86 knockdown in dendritic cells regulates Th1/Th2 cytokine production in asthmatic mice.
Experimental and therapeutic medicine
Li JG,DU YM,Yan ZD,Yan J,Zhuansun YX,Chen R,Zhang W,Feng SL,Ran PX
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Flagellin is a strong vaginal adjuvant of a therapeutic vaccine for genital cancer.
Oncoimmunology
Lee SE,Hong SH,Verma V,Lee YS,Duong TN,Jeong K,Uthaman S,Sung YC,Lee JT,Park IK,Min JJ,Rhee JH
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunofluorescence
Mon Feb 01 00:00:00 EST 2016
Flagellin is a strong vaginal adjuvant of a therapeutic vaccine for genital cancer.
Oncoimmunology
Lee SE,Hong SH,Verma V,Lee YS,Duong TN,Jeong K,Uthaman S,Sung YC,Lee JT,Park IK,Min JJ,Rhee JH
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunofluorescence
Mon Feb 01 00:00:00 EST 2016
Thymic exosomes promote the final maturation of thymocytes.
Scientific reports
Lundberg V,Berglund M,Skogberg G,Lindgren S,Lundqvist C,Gudmundsdottir J,Thörn K,Telemo E,Ekwall O
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Tue Nov 08 00:00:00 EST 2016
Antigen presenting cell abnormalities in the Cln3(-/-) mouse model of juvenile neuronal ceroid lipofuscinosis.
Biochimica et biophysica acta
Hersrud SL,Kovács AD,Pearce DA
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Western Blot
Fri Jul 01 00:00:00 EDT 2016
Antigen presenting cell abnormalities in the Cln3(-/-) mouse model of juvenile neuronal ceroid lipofuscinosis.
Biochimica et biophysica acta
Hersrud SL,Kovács AD,Pearce DA
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Western Blot
Fri Jul 01 00:00:00 EDT 2016
Antigen presenting cell abnormalities in the Cln3(-/-) mouse model of juvenile neuronal ceroid lipofuscinosis.
Biochimica et biophysica acta
Hersrud SL,Kovács AD,Pearce DA
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Western Blot
Fri Jul 01 00:00:00 EDT 2016
Antigen presenting cell abnormalities in the Cln3(-/-) mouse model of juvenile neuronal ceroid lipofuscinosis.
Biochimica et biophysica acta
Hersrud SL,Kovács AD,Pearce DA
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Western Blot
Fri Jul 01 00:00:00 EDT 2016
Laser Therapy Inhibits Tumor Growth in Mice by Promoting Immune Surveillance and Vessel Normalization.
EBioMedicine
Ottaviani G,Martinelli V,Rupel K,Caronni N,Naseem A,Zandonà L,Perinetti G,Gobbo M,Di Lenarda R,Bussani R,Benvenuti F,Giacca M,Biasotto M,Zacchigna S
14-0114 was used in Flow cytometry/Cell sorting to explore the anti-cancer effect of three laser protocols in B16F10 melanoma and oral carcinogenesis mouse models.
Thu Sep 01 00:00:00 EDT 2016
A Novel Model of Asymptomatic Plasmodium Parasitemia That Recapitulates Elements of the Human Immune Response to Chronic Infection.
PloS one
Fontana MF,Baccarella A,Craft JF,Boyle MJ,McIntyre TI,Wood MD,Thorn KS,Anidi C,Bayat A,Chung MR,Hamburger R,Kim CY,Pearman E,Pham J,Tang JJ,Boon L,Kamya MR,Dorsey G,Feeney ME,Kim CC
14-0114 was used in Flow cytometry/Cell sorting to investigate aspects of the human immune response to asymptomatic persistent Plasmodium infection using a novel animal model.
Wed Aug 02 00:00:00 EDT 2017
Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells.
Nature communications
Göbel K,Pankratz S,Asaridou CM,Herrmann AM,Bittner S,Merker M,Ruck T,Glumm S,Langhauser F,Kraft P,Krug TF,Breuer J,Herold M,Gross CC,Beckmann D,Korb-Pap A,Schuhmann MK,Kuerten S,Mitroulis I,Ruppert C,Nolte MW,Panousis C,Klotz L,Kehrel B,Korn T,Langer HF,Pap T,Nieswandt B,Wiendl H,Chavakis T,Kleinschnitz C,Meuth SG
14-0114 was used in Flow cytometry/Cell sorting to study how immune activation by FXII is mediated by dendritic cells in a CD87-dependent manner, and involves alterations in intracellular cyclic AMP formation.
Wed May 18 00:00:00 EDT 2016
Epigallocatechin-3-gallate (EGCG) inhibits imiquimod-induced psoriasis-like inflammation of BALB/c mice.
BMC complementary and alternative medicine
Zhang S,Liu X,Mei L,Wang H,Fang F
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Wed Aug 31 00:00:00 EDT 2016
Altered gp130 signalling ameliorates experimental colitis via myeloid cell-specific STAT3 activation and myeloid-derived suppressor cells.
Scientific reports
Däbritz J,Judd LM,Chalinor HV,Menheniott TR,Giraud AS
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Feb 05 00:00:00 EST 2016
Epidermal RAF prevents allergic skin disease.
eLife
Raguz J,Jeric I,Niault T,Nowacka JD,Kuzet SE,Rupp C,Fischer I,Biggi S,Borsello T,Baccarini M
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Tue Jul 19 00:00:00 EDT 2016
Epidermal RAF prevents allergic skin disease.
eLife
Raguz J,Jeric I,Niault T,Nowacka JD,Kuzet SE,Rupp C,Fischer I,Biggi S,Borsello T,Baccarini M
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Tue Jul 19 00:00:00 EDT 2016
CXXC finger protein 1 is critical for T-cell intrathymic development through regulating H3K4 trimethylation.
Nature communications
Cao W,Guo J,Wen X,Miao L,Lin F,Xu G,Ma R,Yin S,Hui Z,Chen T,Guo S,Chen W,Huang Y,Liu Y,Wang J,Wei L,Wang L
14-0114 was used in Flow cytometry/Cell sorting to investigate whether the CpG-binding protein Cxxc1 plays a role in thymocyte development.
Mon May 23 00:00:00 EDT 2016
Loss of the Ubiquitin-conjugating Enzyme UBE2W Results in Susceptibility to Early Postnatal Lethality and Defects in Skin, Immune, and Male Reproductive Systems.
The Journal of biological chemistry
Wang B,Merillat SA,Vincent M,Huber AK,Basrur V,Mangelberger D,Zeng L,Elenitoba-Johnson K,Miller RA,Irani DN,Dlugosz AA,Schnell S,Scaglione KM,Paulson HL
14-0114 was used in Flow cytometry/Cell sorting to establish that UBE2W is an important protein for early postnatal survival and the normal functioning of multiple organ systems.
Fri Feb 05 00:00:00 EST 2016
Stat3 Signaling Promotes Survival And Maintenance Of Medullary Thymic Epithelial Cells.
PLoS genetics
Lomada D,Jain M,Bolner M,Reeh KA,Kang R,Reddy MC,DiGiovanni J,Richie ER
14-0114 was used in Flow cytometry/Cell sorting to demonstrate that in addition to the NFkB pathway, Stat3-mediated signals play an essential role in regulating mTEC cellularity and medullary region homeostasis.
Fri Jan 01 00:00:00 EST 2016
PD-1 pathway-mediated regulation of islet-specific CD4+ T cell subsets in autoimmune diabetes.
Immunoendocrinology (Houston, Tex.)
Martinov T,Spanier JA,Pauken KE,Fife BT
14-0114 was used in Flow cytometry/Cell sorting to understand the role of PD-1 in maintaining islet-specific tolerance in diabetes-resistant strains.
Wed Mar 30 00:00:00 EDT 2022
Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.
Scientific reports
Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Wed Jun 15 00:00:00 EDT 2016
KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.
Nature medicine
Shankman LS,Gomez D,Cherepanova OA,Salmon M,Alencar GF,Haskins RM,Swiatlowska P,Newman AA,Greene ES,Straub AC,Isakson B,Randolph GJ,Owens GK
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection.
Nature
Kimmey JM,Huynh JP,Weiss LA,Park S,Kambal A,Debnath J,Virgin HW,Stallings CL
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Thu Dec 24 00:00:00 EST 2015
Structural and functional features of central nervous system lymphatic vessels.
Nature
Louveau A,Smirnov I,Keyes TJ,Eccles JD,Rouhani SJ,Peske JD,Derecki NC,Castle D,Mandell JW,Lee KS,Harris TH,Kipnis J
14-0114 was used in Immunohistochemistry-wholemount to investigate the mechanisms governing the entrance and exit of immune cells from the CNS.
Thu Jul 16 00:00:00 EDT 2015
Commensal-dendritic-cell interaction specifies a unique protective skin immune signature.
Nature
Naik S,Bouladoux N,Linehan JL,Han SJ,Harrison OJ,Wilhelm C,Conlan S,Himmelfarb S,Byrd AL,Deming C,Quinones M,Brenchley JM,Kong HH,Tussiwand R,Murphy KM,Merad M,Segre JA,Belkaid Y
14-0114 was used in Flow cytometry/Cell sorting to demonstrate that defined commensals dominantly affect skin immunity and identify the cellular mediators involved in this specification.
Thu Apr 02 00:00:00 EDT 2015
Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia.
Nature
Wong TN,Ramsingh G,Young AL,Miller CA,Touma W,Welch JS,Lamprecht TL,Shen D,Hundal J,Fulton RS,Heath S,Baty JD,Klco JM,Ding L,Mardis ER,Westervelt P,DiPersio JF,Walter MJ,Graubert TA,Ley TJ,Druley T,Link DC,Wilson RK
14-0114 was used in Flow cytometry/Cell sorting to investigate how prior exposure to cytotoxic therapy influences leukemogenesis and TP53 mutations in t-AML/t-MDS patients.
Thu Feb 26 00:00:00 EST 2015
Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy.
Nature biotechnology
Kim J,Li WA,Choi Y,Lewin SA,Verbeke CS,Dranoff G,Mooney DJ
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease.
Blood
Flynn R,Allen JL,Luznik L,MacDonald KP,Paz K,Alexander KA,Vulic A,Du J,Panoskaltsis-Mortari A,Taylor PA,Poe JC,Serody JS,Murphy WJ,Hill GR,Maillard I,Koreth J,Cutler CS,Soiffer RJ,Antin JH,Ritz J,Chao NJ,Clynes RA,Sarantopoulos S,Blazar BR
14-0114 was used in Flow cytometry/Cell sorting to further evaluate the role of the spleen tyrosine kinase in graft-versus-host disease in multiple murine models and human peripheral blood cells.
Thu Jun 25 00:00:00 EDT 2015
Immature myeloid cells directly contribute to skin tumor development by recruiting IL-17-producing CD4+ T cells.
The Journal of experimental medicine
Ortiz ML,Kumar V,Martner A,Mony S,Donthireddy L,Condamine T,Seykora J,Knight SC,Malietzis G,Lee GH,Moorghen M,Lenox B,Luetteke N,Celis E,Gabrilovich D
14-0114 was used in Immunohistochemistry on frozen tissues to investigate the cellular mechanisms linking chronic inflammation with cancer, showing that immature myeloid cells contribute to skin tumour development by recruiting IL-17-producing CD4+ T cells.
Mon Mar 09 00:00:00 EDT 2015
Bcl11b is essential for group 2 innate lymphoid cell development.
The Journal of experimental medicine
Walker JA,Oliphant CJ,Englezakis A,Yu Y,Clare S,Rodewald HR,Belz G,Liu P,Fallon PG,McKenzie AN
14-0114 was used in Flow cytometry/Cell sorting to study the role of Bcl11b in the differentiation of group 2 innate lymphoid cells.
Mon Jun 01 00:00:00 EDT 2015
Phospholipid oxidation generates potent anti-inflammatory lipid mediators that mimic structurally related pro-resolving eicosanoids by activating Nrf2.
EMBO molecular medicine
Bretscher P,Egger J,Shamshiev A,Trötzmüller M,Köfeler H,Carreira EM,Kopf M,Freigang S
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2015
β-catenin promotes regulatory T-cell responses in tumors by inducing vitamin A metabolism in dendritic cells.
Cancer research
Hong Y,Manoharan I,Suryawanshi A,Majumdar T,Angus-Hill ML,Koni PA,Manicassamy B,Mellor AL,Munn DH,Manicassamy S
14-0114 was used in Flow cytometry/Cell sorting to show that dendritic cells in the tumour microenvironment acquire the ability to metabolise vitamin A to produce retinoic acid, driving immune tolerance.
Sun Feb 15 00:00:00 EST 2015
Atypical chemokine receptor 1 deficiency reduces atherogenesis in ApoE-knockout mice.
Cardiovascular research
Wan W,Liu Q,Lionakis MS,Marino AP,Anderson SA,Swamydas M,Murphy PM
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
Visualized macrophage dynamics and significance of S100A8 in obese fat.
Proceedings of the National Academy of Sciences of the United States of America
Sekimoto R,Fukuda S,Maeda N,Tsushima Y,Matsuda K,Mori T,Nakatsuji H,Nishizawa H,Kishida K,Kikuta J,Maijima Y,Funahashi T,Ishii M,Shimomura I
14-0114 was used in Flow cytometry/Cell sorting to identified the early event exhibiting increased mobility of macrophages, which may be triggered by increased expression of adipose S100A8.
Tue Apr 21 00:00:00 EDT 2015
SOCS3 Deficiency in Myeloid Cells Promotes Tumor Development: Involvement of STAT3 Activation and Myeloid-Derived Suppressor Cells.
Cancer immunology research
Yu H,Liu Y,McFarland BC,Deshane JS,Hurst DR,Ponnazhagan S,Benveniste EN,Qin H
14-0114 was used in Flow cytometry/Cell sorting to assess the effect of genetic deletion of SOCS3 in myeloid cells on tumour growth.
Wed Jul 01 00:00:00 EDT 2015
ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells.
PLoS biology
Gallego-Ortega D,Ledger A,Roden DL,Law AM,Magenau A,Kikhtyak Z,Cho C,Allerdice SL,Lee HJ,Valdes-Mora F,Herrmann D,Salomon R,Young AI,Lee BY,Sergio CM,Kaplan W,Piggin C,Conway JR,Rabinovich B,Millar EK,Oakes SR,Chtanova T,Swarbrick A,Naylor MJ,O'Toole S,Green AR,Timpson P,Gee JM,Ellis IO,Clark SJ,Ormandy CJ
14-0114 was used in Flow cytometry/Cell sorting to implicate ELF5 as a defining factor in the acquisition of the key aspects of the lethal phenotype in luminal A breast cancer.
Tue Dec 01 00:00:00 EST 2015
Characterization of distinct subpopulations of hepatic macrophages in HFD/obese mice.
Diabetes
Morinaga H,Mayoral R,Heinrichsdorff J,Osborn O,Franck N,Hah N,Walenta E,Bandyopadhyay G,Pessentheiner AR,Chi TJ,Chung H,Bogner-Strauss JG,Evans RM,Olefsky JM,Oh DY
14-0114 was used in Flow cytometry/Cell sorting to assess whether Kupffer cells or recruited hepatic macrophages represent the major liver inflammatory cell type in obesity.
Wed Apr 01 00:00:00 EDT 2015
Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells.
Frontiers in immunology
Vogel AJ,Brown DM
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Jul 10 00:00:00 EDT 2015
LynA regulates an inflammation-sensitive signaling checkpoint in macrophages.
eLife
Freedman TS,Tan YX,Skrzypczynska KM,Manz BN,Sjaastad FV,Goodridge HS,Lowell CA,Weiss A
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Oct 30 00:00:00 EDT 2015
Transcription factor c-Rel plays a crucial role in driving anti-CD40-mediated innate colitis.
Mucosal immunology
Visekruna A,Linnerz T,Martinic V,Vachharajani N,Hartmann S,Harb H,Joeris T,Pfefferle PI,Hofer MJ,Steinhoff U
14-0114 was used in Flow cytometry/Cell sorting to investigate the role c-Rel plays in regulating innate lymphoid cells which induce anti-CD40-mediated innate colitis in mice.
Sun Mar 01 00:00:00 EST 2015
The late endosomal adaptor molecule p14 (LAMTOR2) regulates TGFβ1-mediated homeostasis of Langerhans cells.
The Journal of investigative dermatology
Sparber F,Tripp CH,Komenda K,Scheffler JM,Clausen BE,Huber LA,Romani N,Stoitzner P
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
Low doses of imatinib induce myelopoiesis and enhance host anti-microbial immunity.
PLoS pathogens
Napier RJ,Norris BA,Swimm A,Giver CR,Harris WA,Laval J,Napier BA,Patel G,Crump R,Peng Z,Bornmann W,Pulendran B,Buller RM,Weiss DS,Tirouvanziam R,Waller EK,Kalman D
14-0114 was used in Flow cytometry/Cell sorting to demonstrate that potentiation of the immune response by imatinib may facilitate clearance of diverse microbial pathogens.
Sun Mar 01 00:00:00 EST 2015
Low doses of imatinib induce myelopoiesis and enhance host anti-microbial immunity.
PLoS pathogens
Napier RJ,Norris BA,Swimm A,Giver CR,Harris WA,Laval J,Napier BA,Patel G,Crump R,Peng Z,Bornmann W,Pulendran B,Buller RM,Weiss DS,Tirouvanziam R,Waller EK,Kalman D
14-0114 was used in Flow cytometry/Cell sorting to demonstrate that potentiation of the immune response by imatinib may facilitate clearance of diverse microbial pathogens.
Sun Mar 01 00:00:00 EST 2015
The neurotrophic receptor Ntrk2 directs lymphoid tissue neovascularization during Leishmania donovani infection.
PLoS pathogens
Dalton JE,Glover AC,Hoodless L,Lim EK,Beattie L,Kirby A,Kaye PM
14-0114 was used in Flow cytometry/Cell sorting to investigate how Ntrk2 plays a role in the pathologic remodeling of the spleen that accompanies chronic infection.
Sun Feb 01 00:00:00 EST 2015
Peptide-MHC-I from Endogenous Antigen Outnumber Those from Exogenous Antigen, Irrespective of APC Phenotype or Activation.
PLoS pathogens
Sei JJ,Haskett S,Kaminsky LW,Lin E,Truckenmiller ME,Bellone CJ,Buller RM,Norbury CC
14-0114 was used in Flow cytometry/Cell sorting to suggest that direct antigen presentation is the dominant pathway in mice during mousepox.
Mon Jun 01 00:00:00 EDT 2015
The expression of mouse CLEC-2 on leucocyte subsets varies according to their anatomical location and inflammatory state.
European journal of immunology
Lowe KL,Navarro-Núñez L,Bénézech C,Nayar S,Kingston BL,Nieswandt B,Barone F,Watson SP,Buckley CD,Desanti GE
14011482 was used in flow cytometry to assess surface expression of C-type lectin-like receptor 2 on hematopoietic cells from peripheral blood and secondary lymphoid organs
Tue Sep 01 00:00:00 EDT 2015
Oncolytic HSV virotherapy in murine sarcomas differentially triggers an antitumor T-cell response in the absence of virus permissivity.
Molecular therapy oncolytics
Leddon JL,Chen CY,Currier MA,Wang PY,Jung FA,Denton NL,Cripe KM,Haworth KB,Arnold MA,Gross AC,Eubank TD,Goins WF,Glorioso JC,Cohen JB,Grandi P,Hildeman DA,Cripe TP
14-0114 was used in Flow cytometry/Cell sorting to explore the beneficial antitumour cytotoxic T cell response promoted by virotherapy.
Wed Apr 27 00:00:00 EDT 2016
In vivo compartmental analysis of leukocytes in mouse lungs.
American journal of physiology. Lung cellular and molecular physiology
Patel BV,Tatham KC,Wilson MR,O'Dea KP,Takata M
14-0114 was used in Flow cytometry/Cell sorting to present an in vivo antibody-labeling methodology to analyze the subsets of myeloid cells within the three compartments of the lung.
Thu Oct 01 00:00:00 EDT 2015
Enhancement of the proapoptotic properties of newcastle disease virus promotes tumor remission in syngeneic murine cancer models.
Molecular cancer therapeutics
Cuadrado-Castano S,Ayllon J,Mansour M,de la Iglesia-Vicente J,Jordan S,Tripathi S,García-Sastre A,Villar E
14-0114 was used in Flow cytometry/Cell sorting to demonstrate an augmented agent for cancer therapy which exploits the oncolytic properties of Newcastle disease virus.
Fri May 01 00:00:00 EDT 2015
The atypical chemokine receptor ACKR2 suppresses Th17 responses to protein autoantigens.
Immunology and cell biology
Hansell CA,MacLellan LM,Oldham RS,Doonan J,Chapple KJ,Anderson EJ,Linington C,McInnes IB,Nibbs RJ,Goodyear CS
14-0114 was used in Flow cytometry/Cell sorting to investigate the role of ACKR2 in autoimmunity, showing that it suppresses Th17 responses to protein autoantigens.
Sun Feb 01 00:00:00 EST 2015
Intermuscular and perimuscular fat expansion in obesity correlates with skeletal muscle T cell and macrophage infiltration and insulin resistance.
International journal of obesity (2005)
Khan IM,Perrard XY,Brunner G,Lui H,Sparks LM,Smith SR,Wang X,Shi ZZ,Lewis DE,Wu H,Ballantyne CM
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2015
Natural IgM Switches the Function of Lipopolysaccharide-Activated Murine Bone Marrow-Derived Dendritic Cells to a Regulatory Dendritic Cell That Suppresses Innate Inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Lobo PI,Schlegel KH,Bajwa A,Huang L,Kurmaeva E,Wang B,Ye H,Tedder TF,Kinsey GR,Okusa MD
14-0114 was used in Flow cytometry/Cell sorting to investigate how natural IgM anti-leukocyte Abs can switch BMDC to a regulatory phenotype despite the presence of LPS that ordinarily induces BMDC maturation.
Tue Dec 01 00:00:00 EST 2015
Dendritic Cell-Based Vaccines that Utilize Myeloid Rather than Plasmacytoid Cells Offer a Superior Survival Advantage in Malignant Glioma.
Journal of immunology (Baltimore, Md. : 1950)
Dey M,Chang AL,Miska J,Wainwright DA,Ahmed AU,Balyasnikova IV,Pytel P,Han Y,Tobias A,Zhang L,Qiao J,Lesniak MS
14-0114 was used in Flow cytometry/Cell sorting to compare the ability of myeloid and plasmacytoid dendritic cells to generate effective antiglioma immunity.
Wed Jul 01 00:00:00 EDT 2015
Ly6C(high) monocytes control cerebral toxoplasmosis.
Journal of immunology (Baltimore, Md. : 1950)
Biswas A,Bruder D,Wolf SA,Jeron A,Mack M,Heimesaat MM,Dunay IR
14-0114 was used in Flow cytometry/Cell sorting to indicate the critical importance of recruited Ly6C monocytes upon cerebral toxoplasmosis.
Wed Apr 01 00:00:00 EDT 2015
TARM1 Is a Novel Leukocyte Receptor Complex-Encoded ITAM Receptor That Costimulates Proinflammatory Cytokine Secretion by Macrophages and Neutrophils.
Journal of immunology (Baltimore, Md. : 1950)
Radjabova V,Mastroeni P,Skjødt K,Zaccone P,de Bono B,Goodall JC,Chilvers ER,Juss JK,Jones DC,Trowsdale J,Barrow AD
14-0114 was used in Flow cytometry/Cell sorting to identify a novel leukocyte receptor, TARM1, and investigate the mechanisms underlying its proinflammatory effects.
Thu Oct 01 00:00:00 EDT 2015
Cutting edge: NF-κB p65 and c-Rel control epidermal development and immune homeostasis in the skin.
Journal of immunology (Baltimore, Md. : 1950)
Grinberg-Bleyer Y,Dainichi T,Oh H,Heise N,Klein U,Schmid RM,Hayden MS,Ghosh S
14-0114-82 was used in Flow Cytometry to analyse the function of canonical NF-κB in the epidermis using CRE-mediated deletion of p65 and c-Rel in keratinocytes.
Sun Mar 15 00:00:00 EDT 2015
Canonical wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation.
Journal of immunology (Baltimore, Md. : 1950)
Suryawanshi A,Manoharan I,Hong Y,Swafford D,Majumdar T,Taketo MM,Manicassamy B,Koni PA,Thangaraju M,Sun Z,Mellor AL,Munn DH,Manicassamy S
14-0114 was used in Flow cytometry/Cell sorting to study the factors in the tissue microenvironment and signalling networks critical for programming dendritic cells to control chronic inflammation and promote tolerance, showing that Th1/Th17 responses are regulated by canonical Wnt signalling in dendritic cells and suppresses autoimmune neuroinflammation.
Wed Apr 01 00:00:00 EDT 2015
Syk tyrosine kinase is critical for B cell antibody responses and memory B cell survival.
Journal of immunology (Baltimore, Md. : 1950)
Ackermann JA,Nys J,Schweighoffer E,McCleary S,Smithers N,Tybulewicz VL
14-0114 was used in Flow cytometry/Cell sorting to define the contribution of Syk to B cell function.
Fri May 15 00:00:00 EDT 2015
JUNB is a key transcriptional modulator of macrophage activation.
Journal of immunology (Baltimore, Md. : 1950)
Fontana MF,Baccarella A,Pancholi N,Pufall MA,Herbert DR,Kim CC
14-0114 was used in Flow cytometry/Cell sorting to validate putative key transcription factors that control macrophage activation, showing that JUNB is a key transcriptional modulator of activation.
Thu Jan 01 00:00:00 EST 2015
Toll-Like Receptor 4 Is an Essential Upstream Regulator of On-Time Parturition and Perinatal Viability in Mice.
Endocrinology
Wahid HH,Dorian CL,Chin PY,Hutchinson MR,Rice KC,Olson DM,Moldenhauer LM,Robertson SA
14-0114 was used in Flow cytometry/Cell sorting to describe TLR4-mediated regulation of the inflammatory response acting to drive uterine activation and control the timing of labour.
Thu Oct 01 00:00:00 EDT 2015
A far-red fluorescent probe for flow cytometry and image-based functional studies of xenobiotic sequestering macrophages.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Keswani RK,Yoon GS,Sud S,Stringer KA,Rosania GR
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Adjuvants may reduce in vivo transfection levels for DNA vaccination in mice leading to reduced antigen-specific CD8+ T cell responses.
Human vaccines & immunotherapeutics
Rose AH,Hoffmann FW,Hara JH,Urschitz J,Moisyadi S,Hoffmann PR,Bertino P
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Mon May 16 00:00:00 EDT 2016
Inadequate activation of the HBsAg-specific Th cells by APCs leads to hyporesponsiveness to HBsAg vaccine in B10.S mice.
Human vaccines & immunotherapeutics
Li X,Xu J,Lv Z,Wang J,Sun S,Zhu W,Wang B,He R,Qu D
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Tue Apr 19 00:00:00 EDT 2016
Intracellular Listeria monocytogenes comprises a minimal but vital fraction of the intestinal burden following foodborne infection.
Infection and immunity
Jones GS,Bussell KM,Myers-Morales T,Fieldhouse AM,Bou Ghanem EN,D'Orazio SE
14-0114 was used in Flow cytometry/Cell sorting to investigate how mouse-adapted and wild-type L. monocytogenes strains spread to the mesenteric lymph nodes in a foodborne model of listeriosis.
Sat Aug 01 00:00:00 EDT 2015
Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway.
Molecular medicine reports
Huang L,Kong Y,Wang J,Sun J,Shi Q,Qiu YH
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Advanced Glycation End Products Enhance Macrophages Polarization into M1 Phenotype through Activating RAGE/NF-κB Pathway.
BioMed research international
Jin X,Yao T,Zhou Z,Zhu J,Zhang S,Hu W,Shen C
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Mar 18 00:00:00 EDT 2016
Vitamin A Impairs the Reprogramming of Tregs into IL-17-Producing Cells during Intestinal Inflammation.
BioMed research international
Tejón G,Manríquez V,De Calisto J,Flores-Santibáñez F,Hidalgo Y,Crisóstomo N,Fernández D,Sauma D,Mora JR,Bono MR,Rosemblatt M
14-0114 was used in Flow cytometry/Cell sorting to study the contribution of different factors to the reprogramming of iTregs into IL-17-producing cells, showing that vitamin A impairs reprogramming during intestinal inflammation.
Fri Sep 02 00:00:00 EDT 2016
Targeted Mutation of Nuclear Bone Morphogenetic Protein 2 Impairs Secondary Immune Response in a Mouse Model.
BioMed research international
Olsen DS,Goar WA,Nichols BA,Bailey KT,Christensen SL,Merriam KR,Reynolds PR,Wilson E,Weber KS,Bridgewater LC
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
M cell-derived vesicles suggest a unique pathway for trans-epithelial antigen delivery.
Tissue barriers
Sakhon OS,Ross B,Gusti V,Pham AJ,Vu K,Lo DD
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunofluorescence
Fri Apr 03 00:00:00 EDT 2015
M cell-derived vesicles suggest a unique pathway for trans-epithelial antigen delivery.
Tissue barriers
Sakhon OS,Ross B,Gusti V,Pham AJ,Vu K,Lo DD
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunofluorescence
Fri Apr 03 00:00:00 EDT 2015
Granulocyte/Macrophage Colony-stimulating Factor-dependent Dendritic Cells Restrain Lean Adipose Tissue Expansion.
The Journal of biological chemistry
Pamir N,Liu NC,Irwin A,Becker L,Peng Y,Ronsein GE,Bornfeldt KE,Duffield JS,Heinecke JW
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Jun 05 00:00:00 EDT 2015
Filter-Dense Multicolor Microscopy.
PloS one
Kijani S,Yrlid U,Heyden M,Levin M,Borén J,Fogelstrand P
14-0114 was used in Immunofluorescence to demonstrate an enhanced multi-fluorescence setup based on condensed filter sets that significantly increases the number of channels in multicolour microscopy.
Tue Jan 19 00:00:00 EST 2016
dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.
Nature communications
Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Tue Sep 15 00:00:00 EDT 2015
CCR7-dependent trafficking of RORγ⁺ ILCs creates a unique microenvironment within mucosal draining lymph nodes.
Nature communications
Mackley EC,Houston S,Marriott CL,Halford EE,Lucas B,Cerovic V,Filbey KJ,Maizels RM,Hepworth MR,Sonnenberg GF,Milling S,Withers DR
14-0114 was used in Flow cytometry/Cell sorting to investigate whether group 3 innate lymphoid cells migrate from their mucosal and peripheral sites to local draining secondary lymphoid tissues.
Fri Jan 09 00:00:00 EST 2015
IL-21-mediated non-canonical pathway for IL-1β production in conventional dendritic cells.
Nature communications
Wan CK,Li P,Spolski R,Oh J,Andraski AB,Du N,Yu ZX,Dillon CP,Green DR,Leonard WJ
14-0114 was used in Flow cytometry/Cell sorting to investigate the mechanism by which IL-21 induces IL-1β production.
Thu Aug 13 00:00:00 EDT 2015
Testing the role of the FcγRIIB immunoreceptor tyrosine-based inhibitory motif in regulation of the B cell immune response.
Immunity, inflammation and disease
Vuyyuru R,Shen S,Manser T
14-0114 was used in Flow cytometry/Cell sorting to test the role of the FcγRIIB ITIM motif in the regulation of B cell immune response in vivo, showing that a functional ITIM motif is not required for all inhibitory activity of this receptor, however further investigation is required to confirm this.
Tue Sep 01 00:00:00 EDT 2015
Deficient Natural Killer Dendritic Cell Responses Underlay the Induction of Theiler's Virus-Induced Autoimmunity.
mBio
Chastain EM,Getts DR,Miller SD
14-0114 was used in Flow cytometry/Cell sorting to determine that disease-susceptible SJL/J mice lacked a unique innate immune population, which plays a role in early CNS virus clearance.
Tue Aug 04 00:00:00 EDT 2015
Anti-Inflammatory Effects of IL-27 in Zymosan-Induced Peritonitis: Inhibition of Neutrophil Recruitment Partially Explained by Impaired Mobilization from Bone Marrow and Reduced Chemokine Levels.
PloS one
Watzlawick R,Kenngott EE,Liu FD,Schwab JM,Hamann A
14-0114 was used in Flow cytometry/Cell sorting to determine the role of IL-27 in innate immune responses.
Tue May 24 00:00:00 EDT 2016
Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice.
Nature communications
Singh NK,Kotla S,Dyukova E,Traylor JG,Orr AW,Chernoff J,Marion TN,Rao GN
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Wed Jun 24 00:00:00 EDT 2015
Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction.
Nature communications
Rouhani SJ,Eccles JD,Riccardi P,Peske JD,Tewalt EF,Cohen JN,Liblau R,Mäkinen T,Engelhard VH
14-0114 was used in Flow cytometry/Cell sorting to demonstrate that when β-galactosidase (β-gal) is expressed in LECs, β-gal-specific CD8 T cells undergo deletion via the PD-1/PD-L1 and LAG-3/MHC-II pathways.
Fri Apr 10 00:00:00 EDT 2015
Depletion of B220+NK1.1+ cells enhances the rejection of established melanoma by tumor-specific CD4+ T cells.
Oncoimmunology
Wilson KA,Goding SR,Neely HR,Harris KM,Antony PA
14-0114 was used in Flow cytometry/Cell sorting to show that interferon-producing killer dendritic cells are an important inhibitor of the CD4(+) T cell response to melanoma.
Sat Aug 01 00:00:00 EDT 2015
Disease severity and mortality can be independently regulated in a mouse model of experimental graft versus host disease.
PloS one
Galvani RG,Lemos R,Areal RB,Salvador PA,Zamboni DS,Wanderley JL,Bonomo A
14-0114 was used in Magnetic cell separation to investigate the exact cause of death in graft versus host disease, showing that disease severity and mortality can be independently regulated.
Mon Oct 19 00:00:00 EDT 2015
Latent virus infection upregulates CD40 expression facilitating enhanced autoimmunity in a model of multiple sclerosis.
Scientific reports
Casiraghi C,Márquez AC,Shanina I,Horwitz MS
14-0114 was used in Flow cytometry/Cell sorting to investigate the cause of enhanced experimental autoimmune encephalomyelitis following infection with murine γ-herpesvirus 68.
Thu Sep 10 00:00:00 EDT 2015
Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes.
Nature medicine
Clatworthy MR,Aronin CE,Mathews RJ,Morgan NY,Smith KG,Germain RN
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunofluorescence
Mon Dec 01 00:00:00 EST 2014
Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes.
Nature medicine
Clatworthy MR,Aronin CE,Mathews RJ,Morgan NY,Smith KG,Germain RN
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunofluorescence
Mon Dec 01 00:00:00 EST 2014
Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity.
Nature
Westphalen K,Gusarova GA,Islam MN,Subramanian M,Cohen TS,Prince AS,Bhattacharya J
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunofluorescence
Thu Feb 27 00:00:00 EST 2014
High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity.
Nature
Schulz MD,Atay C,Heringer J,Romrig FK,Schwitalla S,Aydin B,Ziegler PK,Varga J,Reindl W,Pommerenke C,Salinas-Riester G,Böck A,Alpert C,Blaut M,Polson SC,Brandl L,Kirchner T,Greten FR,Polson SW,Arkan MC
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Thu Oct 23 00:00:00 EDT 2014
Transmigrating neutrophils shape the mucosal microenvironment through localized oxygen depletion to influence resolution of inflammation.
Immunity
Campbell EL,Bruyninckx WJ,Kelly CJ,Glover LE,McNamee EN,Bowers BE,Bayless AJ,Scully M,Saeedi BJ,Golden-Mason L,Ehrentraut SF,Curtis VF,Burgess A,Garvey JF,Sorensen A,Nemenoff R,Jedlicka P,Taylor CT,Kominsky DJ,Colgan SP
14-0114 was used in Flow cytometry/Cell sorting to investigate whether transmigrating neutrophils influence the transcriptional profile of the surrounding mucosa.
Thu Jan 16 00:00:00 EST 2014
Reducing macrophage proteoglycan sulfation increases atherosclerosis and obesity through enhanced type I interferon signaling.
Cell metabolism
Gordts PLSM,Foley EM,Lawrence R,Sinha R,Lameda-Diaz C,Deng L,Nock R,Glass CK,Erbilgin A,Lusis AJ,Witztum JL,Esko JD
14-0114 was used in Flow cytometry/Cell sorting to investigate the role of heparan sulfate proteoglycans in atherogenesis, showing that reducing macrophage proteoglycan sulfation increases atherosclerosis and obesity.
Tue Nov 04 00:00:00 EST 2014
Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells.
Nature immunology
Mahmud SA,Manlove LS,Schmitz HM,Xing Y,Wang Y,Owen DL,Schenkel JM,Boomer JS,Green JM,Yagita H,Chi H,Hogquist KA,Farrar MA
14-0114 was used in Flow cytometry/Cell sorting to study the role of TNF receptors in the thymic development of Treg cells..
Thu May 01 00:00:00 EDT 2014
Immune cell trafficking from the brain maintains CNS immune tolerance.
The Journal of clinical investigation
Mohammad MG,Tsai VW,Ruitenberg MJ,Hassanpour M,Li H,Hart PH,Breit SN,Sawchenko PE,Brown DA
14-0114 was used in Immunohistochemistry on frozen tissues to investigate pathways for immune cells to traffic from the brain.
Sat Mar 01 00:00:00 EST 2014
Intrinsic TGF-β signaling promotes age-dependent CD8+ T cell polyfunctionality attrition.
The Journal of clinical investigation
Bhadra R,Moretto MM,Castillo JC,Petrovas C,Ferrando-Martinez S,Shokal U,Leal M,Koup RA,Eleftherianos I,Khan IA
14-0114 was used in Flow cytometry/Cell sorting to investigate the progressive loss of CD8+ T cell polyfunctionality during aging, using animals challenged with the obligate intracellular pathogen Encephalitozoon cuniculi.
Sun Jun 01 00:00:00 EDT 2014
Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection.
The Journal of experimental medicine
Penaloza-MacMaster P,Kamphorst AO,Wieland A,Araki K,Iyer SS,West EE,O'Mara L,Yang S,Konieczny BT,Sharpe AH,Freeman GJ,Rudensky AY,Ahmed R
14-0114 was used in Flow cytometry/Cell sorting to investigate a role for T reg cells in exhaustion of virus-specific CD8 T cells.
Mon Aug 25 00:00:00 EDT 2014
Antiviral drug ganciclovir is a potent inhibitor of microglial proliferation and neuroinflammation.
The Journal of experimental medicine
Ding Z,Mathur V,Ho PP,James ML,Lucin KM,Hoehne A,Alabsi H,Gambhir SS,Steinman L,Luo J,Wyss-Coray T
14-0114 was used in Flow cytometry/Cell sorting to suggest that the antiviral drug ganciclovir (GCV) may have beneficial effects in the CNS beyond its antiviral properties.
Mon Feb 10 00:00:00 EST 2014
BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups.
The Journal of experimental medicine
Berres ML,Lim KP,Peters T,Price J,Takizawa H,Salmon H,Idoyaga J,Ruzo A,Lupo PJ,Hicks MJ,Shih A,Simko SJ,Abhyankar H,Chakraborty R,Leboeuf M,Beltrão M,Lira SA,Heym KM,Bigley V,Collin M,Manz MG,McClain K,Merad M,Allen CE
14-0114 was used in Immunofluorescence on frozen tissues to investigate the role of BRAF-V600E mutations in langerhans cell histiocytosis, showing that expression in precursor versus differentiated dendritic cells defines clinically distinct risk groups.
Mon Apr 07 00:00:00 EDT 2014
BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups.
The Journal of experimental medicine
Berres ML,Lim KP,Peters T,Price J,Takizawa H,Salmon H,Idoyaga J,Ruzo A,Lupo PJ,Hicks MJ,Shih A,Simko SJ,Abhyankar H,Chakraborty R,Leboeuf M,Beltrão M,Lira SA,Heym KM,Bigley V,Collin M,Manz MG,McClain K,Merad M,Allen CE
14-0114 was used in Immunofluorescence on frozen tissues to investigate the role of BRAF-V600E mutations in langerhans cell histiocytosis, showing that expression in precursor versus differentiated dendritic cells defines clinically distinct risk groups.
Mon Apr 07 00:00:00 EDT 2014
Progressive replacement of embryo-derived cardiac macrophages with age.
The Journal of experimental medicine
Molawi K,Wolf Y,Kandalla PK,Favret J,Hagemeyer N,Frenzel K,Pinto AR,Klapproth K,Henri S,Malissen B,Rodewald HR,Rosenthal NA,Bajenoff M,Prinz M,Jung S,Sieweke MH
14-0114 was used in Flow cytometry/Cell sorting to report that the embryo-derived population of cardiac macrophages is progressively substituted for monocyte-derived macrophages within the first weeks after birth.
Mon Oct 20 00:00:00 EDT 2014
Modulation of leukocyte infiltration and phenotype in microporous tissue engineering scaffolds via vector induced IL-10 expression.
Biomaterials
Gower RM,Boehler RM,Azarin SM,Ricci CF,Leonard JN,Shea LD
14-0114 was used in Flow cytometry/Cell sorting to investigate if lentiviral IL-10 gene delivery can reduce inflammation following biomaterial implantation.
Sat Feb 01 00:00:00 EST 2014
Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNγ.
Cancer research
Ho PC,Meeth KM,Tsui YC,Srivastava B,Bosenberg MW,Kaech SM
14-0114 was used in Flow cytometry/Cell sorting to investigate whether B-Raf(V600E) inhibitors promote tumor regression with the help of host immunity, showing that they rely on signaling by CD40L and IFNγ.
Sun Jun 15 00:00:00 EDT 2014
Disruption of the immune-checkpoint VISTA gene imparts a proinflammatory phenotype with predisposition to the development of autoimmunity.
Proceedings of the National Academy of Sciences of the United States of America
Wang L,Le Mercier I,Putra J,Chen W,Liu J,Schenk AD,Nowak EC,Suriawinata AA,Li J,Noelle RJ
14-0114 was used in Flow cytometry/Cell sorting to study the effect of VISTA genetic deficiency on T-cell-mediated inflammation, showing that the threshold for activation was lowered and that there was increased susceptibility to autoimmunity.
Tue Oct 14 00:00:00 EDT 2014
Dietary supplementation with high doses of regular vitamin D3 safely reduces diabetes incidence in NOD mice when given early and long term.
Diabetes
Takiishi T,Ding L,Baeke F,Spagnuolo I,Sebastiani G,Laureys J,Verstuyf A,Carmeliet G,Dotta F,Van Belle TL,Gysemans CA,Mathieu C
14-0114 was used in Flow cytometry/Cell sorting to investigate the effect of vitamin D3 administration during different periods of life on diabetes prevention in NOD mice.
Sun Jun 01 00:00:00 EDT 2014
Distinct progenitor origin distinguishes a lineage of dendritic-like cells in spleen.
Frontiers in immunology
Petvises S,O'Neill HC
14-0114 was used in Flow cytometry/Cell sorting to study how a lineage of dendritic-like cells in the spleen are distinguished by distinct progenitor origins.
Wed Jan 15 00:00:00 EST 2014
Central memory CD4+ T cells are responsible for the recombinant Bacillus Calmette-Guérin ΔureC::hly vaccine's superior protection against tuberculosis.
The Journal of infectious diseases
Vogelzang A,Perdomo C,Zedler U,Kuhlmann S,Hurwitz R,Gengenbacher M,Kaufmann SH
14-0114 was used in Flow cytometry/Cell sorting to investigate the T-cell population required for recombinant Bacillus Calmette-Guérin δureC::hly vaccine's enhanced protection against tuberculosis.
Mon Dec 15 00:00:00 EST 2014
Bacterial superantigens promote acute nasopharyngeal infection by Streptococcus pyogenes in a human MHC Class II-dependent manner.
PLoS pathogens
Kasper KJ,Zeppa JJ,Wakabayashi AT,Xu SX,Mazzuca DM,Welch I,Baroja ML,Kotb M,Cairns E,Cleary PP,Haeryfar SM,McCormick JK
14-0114 was used in Flow cytometry/Cell sorting to study how secreted superantigens contribute to the fitness and evolution of S. pyogenes.
Thu May 01 00:00:00 EDT 2014
Distinct APC subtypes drive spatially segregated CD4+ and CD8+ T-cell effector activity during skin infection with HSV-1.
PLoS pathogens
Macleod BL,Bedoui S,Hor JL,Mueller SN,Russell TA,Hollett NA,Heath WR,Tscharke DC,Brooks AG,Gebhardt T
14-0114 was used in Flow cytometry/Cell sorting to study the regulation of T-cell effector function in situ at sites of pathogen replication.
Fri Aug 01 00:00:00 EDT 2014
Few Foxp3⁺ regulatory T cells are sufficient to protect adult mice from lethal autoimmunity.
European journal of immunology
Mayer CT,Ghorbani P,Kühl AA,Stüve P,Hegemann M,Berod L,Gershwin ME,Sparwasser T
14-0114 was used in Flow cytometry/Cell sorting to study the mechanisms underlying why regulatory T cell-depletion fails to cause autoimmunity in adult Depletion of REGulatory T cells mice.
Wed Oct 01 00:00:00 EDT 2014
MyD88-dependent immunity to a natural model of vaccinia virus infection does not involve Toll-like receptor 2.
Journal of virology
Davies ML,Sei JJ,Siciliano NA,Xu RH,Roscoe F,Sigal LJ,Eisenlohr LC,Norbury CC
14-0114 was used in Flow cytometry/Cell sorting to investigate the ability of the innate sensing molecule Toll-like receptor 2 and the signalling molecule MyD88 to influence the innate and adaptive immune response to vaccinia virus following systemic or dermal infection.
Sat Mar 01 00:00:00 EST 2014
Paradoxical resistance to high-fat diet-induced obesity and altered macrophage polarization in mineralocorticoid receptor-overexpressing mice.
American journal of physiology. Endocrinology and metabolism
Kuhn E,Bourgeois C,Keo V,Viengchareun S,Muscat A,Meduri G,Le Menuet D,Fève B,Lombès M
14-0114 was used in Flow cytometry/Cell sorting to investigate the in vivo metabolic impact of the mineralocorticoid receptor (MR), showing that overexpression of MR leads to resistance to high-fat diet-induced obesity and altered macrophage polarisation.
Wed Jan 01 00:00:00 EST 2014
Internalization and TLR-dependent type I interferon production by monocytes in response to Toxoplasma gondii.
Immunology and cell biology
Han SJ,Melichar HJ,Coombes JL,Chan SW,Koshy AA,Boothroyd JC,Barton GM,Robey EA
14-0114 was used in Flow cytometry/Cell sorting to show that inflammatory monocytes, but not neutrophils, produce IFN-β in response to T. gondii infection.
Sat Nov 01 00:00:00 EDT 2014
Colitogenic effector T cells: roles of gut-homing integrin, gut antigen specificity and γδ T cells.
Immunology and cell biology
Do JS,Visperas A,Freeman ML,Iwakura Y,Oukka M,Min B
14-0114 was used in Flow cytometry/Cell sorting to demonstrate that T-cell colitogenicity is achieved through multiple processes, offering a therapeutic rationale by intervening these pathways.
Wed Jan 01 00:00:00 EST 2014
TLR2-dependent activation of β-catenin pathway in dendritic cells induces regulatory responses and attenuates autoimmune inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Manoharan I,Hong Y,Suryawanshi A,Angus-Hill ML,Sun Z,Mellor AL,Munn DH,Manicassamy S
14-0114 was used in Flow cytometry/Cell sorting to investigate how diametric signals from the pathogen recognition receptors TLR2 and dectin-1 are coordinated in dendritic cells to regulate or incite immunity.
Wed Oct 15 00:00:00 EDT 2014
Characterization of conventional and atypical receptors for the chemokine CCL2 on mouse leukocytes.
Journal of immunology (Baltimore, Md. : 1950)
Ford LB,Cerovic V,Milling SW,Graham GJ,Hansell CA,Nibbs RJ
14-0114 was used in Flow cytometry/Cell sorting to define the expression profile, scavenging activity, and ligand specificity of CCL2 receptors on mouse leukocytes.
Tue Jul 01 00:00:00 EDT 2014
IRF4 in dendritic cells inhibits IL-12 production and controls Th1 immune responses against Leishmania major.
Journal of immunology (Baltimore, Md. : 1950)
Akbari M,Honma K,Kimura D,Miyakoda M,Kimura K,Matsuyama T,Yui K
14-0114 was used in Flow cytometry/Cell sorting to investigate the roles of the transcription factor IRF4 in dendritic cells and macrophages in vivo.
Sat Mar 01 00:00:00 EST 2014
IL-21 receptor signalling partially mediates Th2-mediated allergic airway responses.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Lajoie S,Lewkowich I,Herman NS,Sproles A,Pesce JT,Wynn TA,Grusby MJ,Hamid Q,Wills-Karp M
14-0114 was used in Flow cytometry/Cell sorting to suggest that IL-21 plays an important role in the allergic diathesis by enhancing Th2 cytokine production through multiple mechanisms.
Tue Jul 01 00:00:00 EDT 2014
Yersinia pseudotuberculosis efficiently escapes polymorphonuclear neutrophils during early infection.
Infection and immunity
Westermark L,Fahlgren A,Fällman M
14-0114 was used in Immunofluorescence to analyse bacterium-immune cell interactions in the intestinal lymphoid tissues of mice during early Yersinia pseudotuberculosis infection.
Sat Mar 01 00:00:00 EST 2014
Mice deficient in intestinal epithelium cytochrome P450 reductase are prone to acute toxin-induced mucosal damage.
Scientific reports
Ahlawat S,Xie F,Zhu Y,D'Hondt R,Ding X,Zhang QY,Mantis NJ
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunofluorescence
Thu Jul 03 00:00:00 EDT 2014
Systemic sensitization with the protein allergen ovalbumin augments local sensitization in atopic dermatitis.
Journal of inflammation research
Yoo J,Manicone AM,McGuire JK,Wang Y,Parks WC
14-0114 was used in Immunofluorescence to reveal a mouse model of atopic dermatitis that reveals novel insights into the pathogenesis of this complex disease.
Thu Mar 27 00:00:00 EDT 2014
A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking β-glucans.
PloS one
Dong B,Li D,Li R,Chen SC,Liu W,Liu W,Chen L,Chen Y,Zhang X,Tong Z,Xia Y,Xia P,Wang Y,Duan Y
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2015
Identification of Toll-like receptor 9 as parapoxvirus ovis-sensing receptor in plasmacytoid dendritic cells.
PloS one
von Buttlar H,Siegemund S,Büttner M,Alber G
14-0114 was used in an ELISA assay to identify endosomal TLR9 as PPVO-sensing receptor in pDC.
Tue Nov 10 00:00:00 EST 2015
A flagellin-derived toll-like receptor 5 agonist stimulates cytotoxic lymphocyte-mediated tumor immunity.
PloS one
Leigh ND,Bian G,Ding X,Liu H,Aygun-Sunar S,Burdelya LG,Gudkov AV,Cao X
14-0114 was used in Flow cytometry/Cell sorting to assess the immunogenic capabilities of CBLB502, a toll-like receptor 5 agonist.
Wed Sep 17 00:00:00 EDT 2014
Nfatc2 and Tob1 have non-overlapping function in T cell negative regulation and tumorigenesis.
PloS one
May SL,Zhou Q,Lewellen M,Carter CM,Coffey D,Highfill SL,Bucher CM,Matise I,Morse HC,O'Sullivan MG,Schutten M,Johnson C,Bellgrau D,Blazar BR,Modiano JF
14-0114 was used in Flow cytometry/Cell sorting to study how Nfatc2 and Tob1 are non-redundant regulators of lymphocyte homeostasis.
Mon Oct 19 00:00:00 EDT 2015
P2X7 receptor modulates inflammatory and functional pulmonary changes induced by silica.
PloS one
Monção-Ribeiro LC,Faffe DS,Santana PT,Vieira FS,da Graça CL,Marques-da-Silva C,Machado MN,Caruso-Neves C,Zin WA,Borojevic R,Takiya CM,Coutinho-Silva R
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2015
Hematopoietic progenitor cell lines with myeloid and lymphoid potential.
Nature methods
Redecke V,Wu R,Zhou J,Finkelstein D,Chaturvedi V,High AA,Häcker H
14-0114 was used in Flow cytometry/Cell sorting to develop methods to investigate immune-cell differentiation and function, showing that immortalised hematopoietic progenitor cell lines can be produced, with myeloid and lymphoid potential.
Thu Aug 01 00:00:00 EDT 2013
Innate signaling promotes formation of regulatory nitric oxide-producing dendritic cells limiting T-cell expansion in experimental autoimmune myocarditis.
Circulation
Kania G,Siegert S,Behnke S,Prados-Rosales R,Casadevall A,Lüscher TF,Luther SA,Kopf M,Eriksson U,Blyszczuk P
14-0114 was used in Flow cytometry/Cell sorting to investigate how activation of innate pattern-recognition receptors is critical not only for disease induction but also for counterregulatory mechanisms, protecting the heart from exaggerated autoimmunity.
Tue Jun 11 00:00:00 EDT 2013
Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis.
Nature immunology
Taketomi Y,Ueno N,Kojima T,Sato H,Murase R,Yamamoto K,Tanaka S,Sakanaka M,Nakamura M,Nishito Y,Kawana M,Kambe N,Ikeda K,Taguchi R,Nakamizo S,Kabashima K,Gelb MH,Arita M,Yokomizo T,Nakamura M,Watanabe K,Hirai H,Nakamura M,Okayama Y,Ra C,Aritake K,Urade Y,Morimoto K,Sugimoto Y,Shimizu T,Narumiya S,Hara S,Murakami M
14-0114 was used in Flow cytometry/Cell sorting to report that PLA2G3, a mammalian homolog of anaphylactic bee venom phospholipase A2, regulates mast cell maturation via a lipid mediator circuit.
Sat Jun 01 00:00:00 EDT 2013
Shared and distinct transcriptional programs underlie the hybrid nature of iNKT cells.
Nature immunology
Cohen NR,Brennan PJ,Shay T,Watts GF,Brigl M,Kang J,Brenner MB
14-0114 was used in Flow cytometry/Cell sorting to profile gene expression in invariant natural killer T cells during ontogeny and in peripheral subsets.
Tue Jan 01 00:00:00 EST 2013
Inflammatory neovascularization during graft-versus-host disease is regulated by αv integrin and miR-100.
Blood
Leonhardt F,Grundmann S,Behe M,Bluhm F,Dumont RA,Braun F,Fani M,Riesner K,Prinz G,Hechinger AK,Gerlach UV,Dierbach H,Penack O,Schmitt-Gräff A,Finke J,Weber WA,Zeiser R
14-0114-82 was used in Flow Cytometry to identify negative regulation of GvHD-related neovascularization by miR-100.
Thu Apr 25 00:00:00 EDT 2013
Direct and indirect antigen presentation lead to deletion of donor-specific T cells after in utero hematopoietic cell transplantation in mice.
Blood
Nijagal A,Derderian C,Le T,Jarvis E,Nguyen L,Tang Q,Mackenzie TC
14-0114 was used in Flow cytometry/Cell sorting to investigate the mechanisms of antigen presentation that induce a tolerant post-transplant immune response.
Thu May 30 00:00:00 EDT 2013
Immune response to RB1-regulated senescence limits radiation-induced osteosarcoma formation.
The Journal of clinical investigation
Kansara M,Leong HS,Lin DM,Popkiss S,Pang P,Garsed DW,Walkley CR,Cullinane C,Ellul J,Haynes NM,Hicks R,Kuijjer ML,Cleton-Jansen AM,Hinds PW,Smyth MJ,Thomas DM
14-0114 was used in Flow cytometry/Cell sorting to indicate that overcoming the immune response to senescence is a rate-limiting step in the formation of IR-induced osteosarcoma.
Sun Dec 01 00:00:00 EST 2013
B and T lymphocyte attenuator expression on CD4+ T-cells associates with sepsis and subsequent infections in ICU patients.
Critical care (London, England)
Shubin NJ,Monaghan SF,Heffernan DS,Chung CS,Ayala A
14-0114 was used in Flow cytometry/Cell sorting to evaluate the role of B and T lymphocyte attenuator, an immune-regulatory receptor, in driving lymphocyte dysfunction and apoptosis during sepsis.
Fri Nov 29 00:00:00 EST 2013
Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation.
The Journal of experimental medicine
Mielke LA,Jones SA,Raverdeau M,Higgs R,Stefanska A,Groom JR,Misiak A,Dungan LS,Sutton CE,Streubel G,Bracken AP,Mills KH
14-0114 was used in Flow cytometry/Cell sorting to provide novel insights into the molecular events controlling IL-22 transcription.
Mon Jun 03 00:00:00 EDT 2013
Genetic deletion of chemokine receptor Ccr7 exacerbates atherogenesis in ApoE-deficient mice.
Cardiovascular research
Wan W,Lionakis MS,Liu Q,Roffê E,Murphy PM
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
Motile invaded neutrophils in the small intestine of Toxoplasma gondii-infected mice reveal a potential mechanism for parasite spread.
Proceedings of the National Academy of Sciences of the United States of America
Coombes JL,Charsar BA,Han SJ,Halkias J,Chan SW,Koshy AA,Striepen B,Robey EA
14-0114 was used in Flow cytometry/Cell sorting to explore the parasite-host interaction between Toxoplasma gondii and intestinal immune cells.
Tue May 21 00:00:00 EDT 2013
Anti-CTLA-4 antibodies of IgG2a isotype enhance antitumor activity through reduction of intratumoral regulatory T cells.
Cancer immunology research
Selby MJ,Engelhardt JJ,Quigley M,Henning KA,Chen T,Srinivasan M,Korman AJ
14-0114 was used in Flow cytometry/Cell sorting to analyse the mechanism of action of anti-CTLA-4 antibodies against tumours in greater detail.
Mon Jul 01 00:00:00 EDT 2013
Generation of hypoallergenic neoglycoconjugates for dendritic cell targeted vaccination: a novel tool for specific immunotherapy.
Journal of controlled release : official journal of the Controlled Release Society
Weinberger EE,Himly M,Myschik J,Hauser M,Altmann F,Isakovic A,Scheiblhofer S,Thalhamer J,Weiss R
14-0114 was used in Flow cytometry/Cell sorting to investigate carbohydrate-mediated targeting of allergens to dermal antigen-presenting cells and its influence on immunogenicity and allergenicity.
Mon Jan 28 00:00:00 EST 2013
Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation.
PLoS biology
Peine M,Rausch S,Helmstetter C,Fröhlich A,Hegazy AN,Kühl AA,Grevelding CG,Höfer T,Hartmann S,Löhning M
14-0114 was used in Flow cytometry/Cell sorting to characterise Th1/Th2 hybrid cells and assess their role in inflammation.
Thu Mar 06 00:00:00 EST 2014
CX(3)CR1(+) macrophages support IL-22 production by innate lymphoid cells during infection with Citrobacter rodentium.
Mucosal immunology
Manta C,Heupel E,Radulovic K,Rossini V,Garbi N,Riedel CU,Niess JH
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2013
CX(3)CR1(+) macrophages support IL-22 production by innate lymphoid cells during infection with Citrobacter rodentium.
Mucosal immunology
Manta C,Heupel E,Radulovic K,Rossini V,Garbi N,Riedel CU,Niess JH
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2013
Programmed death receptor-1/programmed death receptor ligand-1 blockade after transient lymphodepletion to treat myeloma.
Journal of immunology (Baltimore, Md. : 1950)
Kearl TJ,Jing W,Gershan JA,Johnson BD
14-0114 was used in Flow cytometry/Cell sorting to demonstrate that a blockade of the PD-1/PD-L1 pathway yields positive antitumour results.
Sat Jun 01 00:00:00 EDT 2013
Syndecan-1, a cell surface proteoglycan, negatively regulates initial leukocyte recruitment to the brain across the choroid plexus in murine experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950)
Zhang X,Wu C,Song J,Götte M,Sorokin L
14-0114 was used in Flow cytometry/Cell sorting to investigate how the choroid plexus epithelium is a novel source of IL-6 in EAE and demonstrate that its expression negatively correlates with syndecan-1 expression at this site.
Fri Nov 01 00:00:00 EDT 2013
The influence of T cell Ig mucin-3 signaling on central nervous system autoimmune disease is determined by the effector function of the pathogenic T cells.
Journal of immunology (Baltimore, Md. : 1950)
Lee SY,Goverman JM
14-0114 was used in Flow cytometry/Cell sorting to analyse the role of Tim-3 signalling within various innate immune cells on the development of experimental autoimmune encephalomyelitis.
Wed May 15 00:00:00 EDT 2013
Inoculation dose of Mycobacterium tuberculosis does not influence priming of T cell responses in lymph nodes.
Journal of immunology (Baltimore, Md. : 1950)
Myers AJ,Marino S,Kirschner DE,Flynn JL
14-0114 was used in Flow cytometry/Cell sorting to investigate whether infection with higher aerosolised inocula would lead to increased priming of M. tuberculosis-specific T cells in the lung-draining lymph node.
Wed May 01 00:00:00 EDT 2013
Examining T cells at vaccine sites of tumor-bearing hosts provides insights to dysfunctional T-cell immunity.
Journal of immunotherapy (Hagerstown, Md. : 1997)
Barr KM,Jing W,Hallett WH,Gershan JA,Johnson BD
14-0114 was used in Flow cytometry/Cell sorting to examine immune effectors at vaccine sites to identify mechanisms responsible for the generation of ineffective antitumor immunity, providing insights to dysfunctional T-cell immunity.
Tue Jan 01 00:00:00 EST 2013
SAP modulates B cell functions in a genetic background-dependent manner.
Immunology letters
Detre C,Yigit B,Keszei M,Castro W,Magelky EM,Terhorst C
14-0114 was used in Flow cytometry/Cell sorting to investigate the mechanism by which SLAM-associated protein modulates B cell functions.
Sat Jun 01 00:00:00 EDT 2013
Toll-like receptor 7 mediates early innate immune responses to malaria.
Infection and immunity
Baccarella A,Fontana MF,Chen EC,Kim CC
14-0114 was used in Flow cytometry/Cell sorting to investigate other MYD88-dependent receptors contributing to antimalarial responses, showing that toll-like receptor 7 mediates early innate immune responses to malaria.
Sun Dec 01 00:00:00 EST 2013
Hepatic crown-like structure: a unique histological feature in non-alcoholic steatohepatitis in mice and humans.
PloS one
Itoh M,Kato H,Suganami T,Konuma K,Marumoto Y,Terai S,Sakugawa H,Kanai S,Hamaguchi M,Fukaishi T,Aoe S,Akiyoshi K,Komohara Y,Takeya M,Sakaida I,Ogawa Y
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunofluorescence
Sun Oct 12 00:00:00 EDT 2014
Gr1(int)CD11b+ myeloid-derived suppressor cells in Mycobacterium tuberculosis infection.
PloS one
Obregón-Henao A,Henao-Tamayo M,Orme IM,Ordway DJ
14-0114 was used in Flow cytometry/Cell sorting to compare the bacterial burden, lung pathology and Gr1(int)CD11b(+) myeloid-derived suppressor cell immune responses in M. tuberculosis infected mice.
Fri Jun 20 00:00:00 EDT 2014
Bile acid receptor activation modulates hepatic monocyte activity and improves nonalcoholic fatty liver disease.
The Journal of biological chemistry
McMahan RH,Wang XX,Cheng LL,Krisko T,Smith M,El Kasmi K,Pruzanski M,Adorini L,Golden-Mason L,Levi M,Rosen HR
14-0114 was used in Flow cytometry/Cell sorting to demonstrate that FXR/TGR5 activation coordinates the immune phenotype of monocytes and macrophages.
Fri Apr 26 00:00:00 EDT 2013
Neutralization of TSLP inhibits airway remodeling in a murine model of allergic asthma induced by chronic exposure to house dust mite.
PloS one
Chen ZG,Zhang TT,Li HT,Chen FH,Zou XL,Ji JZ,Chen H
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Tue Aug 20 00:00:00 EDT 2013
Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/- mice.
Nature
Devkota S,Wang Y,Musch MW,Leone V,Fehlner-Peach H,Nadimpalli A,Antonopoulos DA,Jabri B,Chang EB
14-0114 was used in Flow cytometry/Cell sorting to show that different dietary fat change the conditions for microbial assemblage in the digestive system in a T helper 1 cell dependent manner.
Thu Jul 05 00:00:00 EDT 2012
IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia.
Nature immunology
Wang Y,Szretter KJ,Vermi W,Gilfillan S,Rossini C,Cella M,Barrow AD,Diamond MS,Colonna M
14-0114 was used in Flow cytometry/Cell sorting to investigate whether IL-34 is responsible for the lack of Langerhans cells and microglia in CSF1R-deficient mice.
Sun Jun 24 00:00:00 EDT 2012
Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells.
Blood
Tewalt EF,Cohen JN,Rouhani SJ,Guidi CJ,Qiao H,Fahl SP,Conaway MR,Bender TP,Tung KS,Vella AT,Adler AJ,Chen L,Engelhard VH
14-0114 was used in Flow cytometry/Cell sorting to demonstrate that LECs mediate deletion only via programmed cell death-1 (PD-1) ligand 1.
Thu Dec 06 00:00:00 EST 2012
Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice.
The Journal of experimental medicine
Billiard F,Lobry C,Darrasse-Jèze G,Waite J,Liu X,Mouquet H,DaNave A,Tait M,Idoyaga J,Leboeuf M,Kyratsous CA,Burton J,Kalter J,Klinakis A,Zhang W,Thurston G,Merad M,Steinman RM,Murphy AJ,Yancopoulos GD,Aifantis I,Skokos D
14-0114 was used in Immunofluorescence on frozen tissues to investigate how Dll4-Notch signaling affects pro-T cell fate and thymic DC development, showing that it is a novel Flt3-independent pathway for DC development and autoimmunity.
Mon May 07 00:00:00 EDT 2012
Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice.
The Journal of experimental medicine
Billiard F,Lobry C,Darrasse-Jèze G,Waite J,Liu X,Mouquet H,DaNave A,Tait M,Idoyaga J,Leboeuf M,Kyratsous CA,Burton J,Kalter J,Klinakis A,Zhang W,Thurston G,Merad M,Steinman RM,Murphy AJ,Yancopoulos GD,Aifantis I,Skokos D
14-0114 was used in Immunofluorescence on frozen tissues to investigate how Dll4-Notch signaling affects pro-T cell fate and thymic DC development, showing that it is a novel Flt3-independent pathway for DC development and autoimmunity.
Mon May 07 00:00:00 EDT 2012
Identification of a genetic locus controlling bacteria-driven colitis and associated cancer through effects on innate inflammation.
The Journal of experimental medicine
Boulard O,Kirchberger S,Royston DJ,Maloy KJ,Powrie FM
14-0114 was used in Flow cytometry/Cell sorting to investigate the genetic factors influencing the progression from Helicobacter hepaticus-driven colitis to tumorigenesis in a mouse model.
Mon Jul 02 00:00:00 EDT 2012
Lymphotoxin-beta receptor blockade induces inflammation and fibrosis in tolerized cardiac allografts.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Nakayama Y,Bromberg JS
14-0114 was used in Immunohistochemistry to study the effect of LTβRIg treatment in a murine cardiac allograft model.
Sat Sep 01 00:00:00 EDT 2012
Lack of IL-4 receptor expression on T helper cells reduces T helper 2 cell polyfunctionality and confers resistance in allergic bronchopulmonary mycosis.
Mucosal immunology
Müller U,Piehler D,Stenzel W,Köhler G,Frey O,Held J,Grahnert A,Richter T,Eschke M,Kamradt T,Brombacher F,Alber G
14-0114 was used in Flow cytometry/Cell sorting to study the function of the interleukin-4 receptor on T helper cells in pulmonary cryptococcosis.
Tue May 01 00:00:00 EDT 2012
Lung B cells promote early pathogen dissemination and hasten death from inhalation anthrax.
Mucosal immunology
Rayamajhi M,Delgado C,Condon TV,Riches DW,Lenz LL
14-0114 was used in Flow cytometry/Cell sorting to investigate mechanisms of Bacillus anthracis spore traffic from the lungs to the lung-draining lymph nodes in a mouse model of inhalation anthrax.
Sun Jul 01 00:00:00 EDT 2012
Serpinb9 (Spi6)-deficient mice are impaired in dendritic cell-mediated antigen cross-presentation.
Immunology and cell biology
Rizzitelli A,Meuter S,Vega Ramos J,Bird CH,Mintern JD,Mangan MS,Villadangos J,Bird PI
14-0114 was used in Flow cytometry/Cell sorting to investigate the role of Serpinb9 in dendritic cells.
Mon Oct 01 00:00:00 EDT 2012
Tal1 regulates osteoclast differentiation through suppression of the master regulator of cell fusion DC-STAMP.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Courtial N,Smink JJ,Kuvardina ON,Leutz A,Göthert JR,Lausen J
14-0114 was used in Flow cytometry/Cell sorting to show that Tal1 is expressed in osteoclasts and that loss of Tal1 in osteoclast progenitors leads to altered expression of >1200 genes.
Wed Feb 01 00:00:00 EST 2012
Epithelial expression of the cytosolic retinoid chaperone cellular retinol binding protein II is essential for in vivo imprinting of local gut dendritic cells by lumenal retinoids.
The American journal of pathology
McDonald KG,Leach MR,Brooke KWM,Wang C,Wheeler LW,Hanly EK,Rowley CW,Levin MS,Wagner M,Li E,Newberry RD
14-0114 was used in Flow cytometry/Cell sorting to study dendritic cell production of all-trans retinoic acid (ATRA) in vivo.
Thu Mar 01 00:00:00 EST 2012
A TLR5 agonist enhances CD8(+) T cell-mediated graft-versus-tumor effect without exacerbating graft-versus-host disease.
Journal of immunology (Baltimore, Md. : 1950)
Ding X,Bian G,Leigh ND,Qiu J,McCarthy PL,Liu H,Aygun-Sunar S,Burdelya LG,Gudkov AV,Cao X
14-0114 was used in Flow cytometry/Cell sorting to investigate the effect of CBLB502 on graft-versus-tumour activity.
Thu Nov 15 00:00:00 EST 2012
RGS16 attenuates pulmonary Th2/Th17 inflammatory responses.
Journal of immunology (Baltimore, Md. : 1950)
Shankar SP,Wilson MS,DiVietro JA,Mentink-Kane MM,Xie Z,Wynn TA,Druey KM
14-0114 was used in Flow cytometry/Cell sorting to show that RGS16 constrains pulmonary inflammation by regulating chemokine-induced T cell trafficking.
Fri Jun 15 00:00:00 EDT 2012
Glucocorticoids relieve collectin-driven suppression of apoptotic cell uptake in murine alveolar macrophages through downregulation of SIRPα.
Journal of immunology (Baltimore, Md. : 1950)
McCubbrey AL,Sonstein J,Ames TM,Freeman CM,Curtis JL
14-0114 was used in Flow cytometry/Cell sorting to determine whether glucocorticoid treatment acts to increase apoptotic cell uptake by differentiated tissue macrophages.
Sun Jul 01 00:00:00 EDT 2012
Exposure to nicotine adversely affects the dendritic cell system and compromises host response to vaccination.
Journal of immunology (Baltimore, Md. : 1950)
Nouri-Shirazi M,Guinet E
14-0114 was used in Flow cytometry/Cell sorting to investigate the causal relationship between nicotine-induced dendritic cell alterations and host response to vaccines.
Thu Mar 01 00:00:00 EST 2012
An anti-nucleic acid antibody delivers antigen to the cross-presentation pathway in dendritic cells and potentiates therapeutic antitumor effects.
Journal of immunology (Baltimore, Md. : 1950)
Pham CD,Woo MY,Kim YS,Park S,Kwon MH
14-0114 was used in Flow cytometry/Cell sorting to report a new antigenic carrier molecule which facilitates the inhibition of in vivo tumour growth.
Sat Dec 15 00:00:00 EST 2012
Alum increases antigen uptake, reduces antigen degradation and sustains antigen presentation by DCs in vitro.
Immunology letters
Ghimire TR,Benson RA,Garside P,Brewer JM
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2012
Differential gene expression in mice infected with distinct Toxoplasma strains.
Infection and immunity
Hill RD,Gouffon JS,Saxton AM,Su C
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2012
Depletion of B2 but not B1a B cells in BAFF receptor-deficient ApoE mice attenuates atherosclerosis by potently ameliorating arterial inflammation.
PloS one
Kyaw T,Tay C,Hosseini H,Kanellakis P,Gadowski T,MacKay F,Tipping P,Bobik A,Toh BH
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunohistochemistry
Mon May 14 00:00:00 EDT 2012
Extra-thymic physiological T lineage progenitor activity is exclusively confined to cells expressing either CD127, CD90, or high levels of CD117.
PloS one
Saran N,Pommerencke J,Witzlau K,Regelin M,Krueger A
14-0114 was used in Flow cytometry/Cell sorting to suggest that a physiological thymic microenvironment does not optimally support T cell differentiation from triple negative precursors.
Mon Jun 18 00:00:00 EDT 2012
Engineered hepatitis B virus surface antigen L protein particles for in vivo active targeting of splenic dendritic cells.
International journal of nanomedicine
Matsuo H,Yoshimoto N,Iijima M,Niimi T,Jung J,Jeong SY,Choi EK,Sewaki T,Arakawa T,Kuroda S
14-0114 was used in Blocking experiments to demonstrate that the α-CD11cZZ-BNC complex is a useful probe for in vivo imaging of dendritic cells.
Thu Feb 21 00:00:00 EST 2013
Pilus adhesin RrgA interacts with complement receptor 3, thereby affecting macrophage function and systemic pneumococcal disease.
mBio
Orrskog S,Rounioja S,Spadafina T,Gallotta M,Norman M,Hentrich K,Fälker S,Ygberg-Eriksson S,Hasenberg M,Johansson B,Uotila LM,Gahmberg CG,Barocchi M,Gunzer M,Normark S,Henriques-Normark B
14-0114 was used in Blocking experiments to investigate the role of the pilus-associated RrgA adhesin in pneumococcal interactions with murine and human macrophages.
Wed Dec 26 00:00:00 EST 2012
The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor.
Nature immunology
Papadopoulou AS,Dooley J,Linterman MA,Pierson W,Ucar O,Kyewski B,Zuklys S,Hollander GA,Matthys P,Gray DH,De Strooper B,Liston A
14-0114 was used in Flow cytometry/Cell sorting to find that the microRNA network dependent on the endoribonuclease Dicer, was critical for diminishing the sensitivity of the thymic epithelium to simulated infection signals.
Sun Dec 18 00:00:00 EST 2011
A novel role for IL-22R1 as a driver of inflammation.
Blood
Savan R,McFarland AP,Reynolds DA,Feigenbaum L,Ramakrishnan K,Karwan M,Shirota H,Klinman DM,Dunleavy K,Pittaluga S,Anderson SK,Donnelly RP,Wilson WH,Young HA
14-0114 was used in Flow cytometry/Cell sorting to document a previously unknown role of IL-22R1 in inflammation and identifies the involvement of IL-22R1/IL-22 in ALK(+)ALCL.
Thu Jan 13 00:00:00 EST 2011
Tissue-specific expression of B7x protects from CD4 T cell-mediated autoimmunity.
The Journal of experimental medicine
Wei J,Loke P,Zang X,Allison JP
14-0114 was used in Flow cytometry/Cell sorting to investigate the role of B7x in maintaining peripheral tolerance and protecting from CD4 T cell-mediated autoimmunity.
Mon Aug 01 00:00:00 EDT 2011
IFN-γ- and IL-10-expressing virus epitope-specific Foxp3(+) T reg cells in the central nervous system during encephalomyelitis.
The Journal of experimental medicine
Zhao J,Zhao J,Fett C,Trandem K,Fleming E,Perlman S
14-0114 was used in Flow cytometry/Cell sorting to show that pathogen epitope-specific Foxp3(+) T reg cells can be identified on the basis of cytokine production.
Mon Aug 01 00:00:00 EDT 2011
Chemokines control naive CD8+ T cell selection of optimal lymph node antigen presenting cells.
The Journal of experimental medicine
Hickman HD,Li L,Reynoso GV,Rubin EJ,Skon CN,Mays JW,Gibbs J,Schwartz O,Bennink JR,Yewdell JW
14-0114 was used in Flow cytometry/Cell sorting to demonstrate the ability of chemokines to assist antiviral CD8(+) T cells in distinguishing between antigen presenting cells.
Mon Nov 21 00:00:00 EST 2011
Chemokines control naive CD8+ T cell selection of optimal lymph node antigen presenting cells.
The Journal of experimental medicine
Hickman HD,Li L,Reynoso GV,Rubin EJ,Skon CN,Mays JW,Gibbs J,Schwartz O,Bennink JR,Yewdell JW
14-0114 was used in Flow cytometry/Cell sorting to demonstrate the ability of chemokines to assist antiviral CD8(+) T cells in distinguishing between antigen presenting cells.
Mon Nov 21 00:00:00 EST 2011
VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses.
The Journal of experimental medicine
Wang L,Rubinstein R,Lines JL,Wasiuk A,Ahonen C,Guo Y,Lu LF,Gondek D,Wang Y,Fava RA,Fiser A,Almo S,Noelle RJ
14-0114 was used in Flow cytometry/Cell sorting to show that VISTA has functional activities that are nonredundant with other Ig superfamily members and may play a role in the development of autoimmunity.
Mon Mar 14 00:00:00 EDT 2011
Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORgamma t and LTi cells.
The Journal of experimental medicine
Lochner M,Ohnmacht C,Presley L,Bruhns P,Si-Tahar M,Sawa S,Eberl G
14-0114 was used in Immunofluorescence to investigate potential for intestinal immunodeficiency compensation by increased lymphoid tissue genesis.
Mon Jan 17 00:00:00 EST 2011
Induction of potent anti-tumor responses while eliminating systemic side effects via liposome-anchored combinatorial immunotherapy.
Biomaterials
Kwong B,Liu H,Irvine DJ
14-0114 was used in Flow cytometry/Cell sorting to investigate whether systemic exposure to immuno-agonist compounds could be limited to local tumour tissue, showing that liposome-anchored combinatorial immunotherapy could induce potent anti-tumor response.
Mon Aug 01 00:00:00 EDT 2011
Maximal T cell-mediated antitumor responses rely upon CCR5 expression in both CD4(+) and CD8(+) T cells.
Cancer research
González-Martín A,Gómez L,Lustgarten J,Mira E,Mañes S
14-0114 was used in Flow cytometry/Cell sorting to investigate the relevance of the chemokine receptor CCR5 in tumoural immune control.
Mon Aug 15 00:00:00 EDT 2011
Memory type 2 helper T cells induce long-lasting antitumor immunity by activating natural killer cells.
Cancer research
Kitajima M,Ito T,Tumes DJ,Endo Y,Onodera A,Hashimoto K,Motohashi S,Yamashita M,Nishimura T,Ziegler SF,Nakayama T
14-0114 was used in Flow cytometry/Cell sorting to demonstrate that memory Th2 cells can induce antitumor immunity through IL-4-induced activation of NK cells.
Fri Jul 15 00:00:00 EDT 2011
High-mobility group box protein 1 neutralization reduces development of diet-induced atherosclerosis in apolipoprotein e-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology
Kanellakis P,Agrotis A,Kyaw TS,Koulis C,Ahrens I,Mori S,Takahashi HK,Liu K,Peter K,Nishibori M,Bobik A
14-0114 was used in Immunohistochemistry to reveal that HMGB1 augments atherosclerotic lesion development by stimulating macrophage migration and modulating proinflammatory mediators, and represents a potential therapeutic target for atherosclerosis.
Tue Feb 01 00:00:00 EST 2011
CD11b⁺, Ly6G⁺ cells produce type I interferon and exhibit tissue protective properties following peripheral virus infection.
PLoS pathogens
Fischer MA,Davies ML,Reider IE,Heipertz EL,Epler MR,Sei JJ,Ingersoll MA,Rooijen NV,Randolph GJ,Norbury CC
14-0114 was used in Flow cytometry/Cell sorting to demonstrate that innate immune effector cells contain a peripheral poxvirus infection, preventing systemic spread of the virus.
Tue Nov 01 00:00:00 EDT 2011
CCAAT/enhancer binding protein-δ expression by dendritic cells regulates CNS autoimmune inflammatory disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Tsai VW,Mohammad MG,Tolhurst O,Breit SN,Sawchenko PE,Brown DA
14-0114 was used in Immunohistochemistry to investigate the mechanisms involving C/EBPδ in mediating bystander neuronal injury and CNS autoimmune inflammatory disease.
Wed Nov 30 00:00:00 EST 2011
Macrophages counteract demyelination in a mouse model of globoid cell leukodystrophy.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Kondo Y,Adams JM,Vanier MT,Duncan ID
14-0114 was used in Immunofluorescence to suggest that in globoid cell leukodystrophy, macrophages promote myelin repair.
Wed Mar 09 00:00:00 EST 2011
A critical role for granzymes in antigen cross-presentation through regulating phagocytosis of killed tumor cells.
Journal of immunology (Baltimore, Md. : 1950)
Hoves S,Sutton VR,Haynes NM,Hawkins ED,Fernández Ruiz D,Baschuk N,Sedelies KA,Schnurr M,Stagg J,Andrews DM,Villadangos JA,Trapani JA
14-0114 was used in Flow cytometry/Cell sorting to reveal a critical and previously unsuspected role for granzymes A and B in dictating immunogenicity by influencing the mode of tumour cell death.
Mon Aug 01 00:00:00 EDT 2011
Differential expression of NLRP3 among hematopoietic cells.
Journal of immunology (Baltimore, Md. : 1950)
Guarda G,Zenger M,Yazdi AS,Schroder K,Ferrero I,Menu P,Tardivel A,Mattmann C,Tschopp J
14-0114 was used in Flow cytometry/Cell sorting to characterize NOD-like receptor pyrin domain 3 (NLRP3) expression due to importance in health and disease.
Tue Feb 15 00:00:00 EST 2011
The transport and inactivation kinetics of bacterial lipopolysaccharide influence its immunological potency in vivo.
Journal of immunology (Baltimore, Md. : 1950)
Lu M,Munford RS
14-0114 was used in Flow cytometry/Cell sorting to investigate what happens to LPS within animal tissue.
Thu Sep 15 00:00:00 EDT 2011
Presentation of type B peptide-MHC complexes from hen egg white lysozyme by TLR ligands and type I IFNs independent of H2-DM regulation.
Journal of immunology (Baltimore, Md. : 1950)
Strong BS,Unanue ER
14-0114 was used in Flow cytometry/Cell sorting to study the role of TLR ligands and interferons on the assembly of peptide-MHC II complexes.
Thu Sep 01 00:00:00 EDT 2011
PAD4-mediated neutrophil extracellular trap formation is not required for immunity against influenza infection.
PloS one
Hemmers S,Teijaro JR,Arandjelovic S,Mowen KA
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Tue Nov 15 00:00:00 EST 2011
Localized delivery of interferon-β by Lactobacillus exacerbates experimental colitis.
PloS one
McFarland AP,Savan R,Wagage S,Addison A,Ramakrishnan K,Karwan M,Duong T,Young HA
14-0114 was used in Flow cytometry/Cell sorting to identify a correlation between the loss/down-regulation of IFNAR1 on DCs and exacerbation of colitis.
Fri Feb 18 00:00:00 EST 2011
Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis.
Nature communications
Mkhikian H,Grigorian A,Li CF,Chen HL,Newton B,Zhou RW,Beeton C,Torossian S,Tatarian GG,Lee SU,Lau K,Walker E,Siminovitch KA,Chandy KG,Yu Z,Dennis JW,Demetriou M
14-0114 was used in Flow cytometry/Cell sorting to discover that genetic and the environment converge to dysregulate N-glycosylation in multiple sclerosis.
Tue Sep 20 00:00:00 EDT 2011
Lymphoid organ-resident dendritic cells exhibit unique transcriptional fingerprints based on subset and site.
PloS one
Elpek KG,Bellemare-Pelletier A,Malhotra D,Reynoso ED,Lukacs-Kornek V,DeKruyff RH,Turley SJ
14-0114 was used in Flow cytometry/Cell sorting to investigate whether local environments can influence the transcriptome of DC subsets, showing that lymphoid organ-resident dendritic cells exhibit unique transcriptomes based on site.
Fri Feb 24 00:00:00 EST 2012
The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut.
Immunity
Suzuki K,Maruya M,Kawamoto S,Sitnik K,Kitamura H,Agace WW,Fagarasan S
14-0114 was used in Flow cytometry/Cell sorting to investigate whether follicular dendritic cells within the germinal centers directly contribute to the IgA production in Peyer's patches, showing that sensing of environmental stimuli promotes IgA production.
Fri Jul 23 00:00:00 EDT 2010
Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8(+) T cell responses to influenza.
Nature immunology
Ballesteros-Tato A,León B,Lund FE,Randall TD
14-0114 was used in Flow cytometry/Cell sorting to show that influenza-specific CD8(+) T cell priming was controlled by different dendritic cells at different times after infection.
Mon Mar 01 00:00:00 EST 2010
Comparison of gene expression profiles between human and mouse monocyte subsets.
Blood
Ingersoll MA,Spanbroek R,Lottaz C,Gautier EL,Frankenberger M,Hoffmann R,Lang R,Haniffa M,Collin M,Tacke F,Habenicht AJ,Ziegler-Heitbrock L,Randolph GJ
14-0114 was used in Flow cytometry/Cell sorting to identify how human and mouse monocyte subsets are far more broadly conserved than currently recognised.
Thu Jan 21 00:00:00 EST 2010
Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant.
Blood
Freire T,Zhang X,Dériaud E,Ganneau C,Vichier-Guerre S,Azria E,Launay O,Lo-Man R,Bay S,Leclerc C
14-0114 was used in Flow cytometry/Cell sorting to study dendritic cell antigen uptake and presentation by targeting the antigen receptor, macrophage galactose-type lectin (MGL), with tumor-associated Tn antigens.
Thu Nov 04 00:00:00 EDT 2010
Skin-draining lymph nodes contain dermis-derived CD103(-) dendritic cells that constitutively produce retinoic acid and induce Foxp3(+) regulatory T cells.
Blood
Guilliams M,Crozat K,Henri S,Tamoutounour S,Grenot P,Devilard E,de Bovis B,Alexopoulou L,Dalod M,Malissen B
14-0114 was used in Flow cytometry/Cell sorting to analyse retinoic acid-producing dendritic cell populations in lymphoid and non-lymphoid mouse tissues, and their T reg-inducing abilities.
Thu Mar 11 00:00:00 EST 2010
Separation of graft-versus-host disease from graft-versus-leukemia responses by targeting CC-chemokine receptor 7 on donor T cells.
Blood
Coghill JM,Carlson MJ,Panoskaltsis-Mortari A,West ML,Burgents JE,Blazar BR,Serody JS
14-0114 was used in Flow cytometry/Cell sorting to investigate the role of MHC disparity between donor and recipient, in the attenuated graft-versus-host disease responses of murine T cells lacking CCR7.
Thu Jun 10 00:00:00 EDT 2010
Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation.
The Journal of experimental medicine
Nishikawa Y,Hirota F,Yano M,Kitajima H,Miyazaki J,Kawamoto H,Mouri Y,Matsumoto M
14-0114 was used in Flow cytometry/Cell sorting to investigate the production and maintenance of Aire-expressing medullary thymic epithelial cells.
Mon May 10 00:00:00 EDT 2010
Gap junctions between regulatory T cells and dendritic cells prevent sensitization of CD8(+) T cells.
The Journal of allergy and clinical immunology
Ring S,Karakhanova S,Johnson T,Enk AH,Mahnke K
14-0114 was used in Immunohistochemistry to determine that Treg cells suppress CD8+ T cell sensitisation by interfering with the T-cell stimulatory activity of dendritic cells via intercellular gap junctions.
Fri Jan 01 00:00:00 EST 2010
Notch dimerization is required for leukemogenesis and T-cell development.
Genes & development
Liu H,Chi AW,Arnett KL,Chiang MY,Xu L,Shestova O,Wang H,Li YM,Bhandoola A,Aster JC,Blacklow SC,Pear WS
14-0114 was used in Flow cytometry/Cell sorting to show that dimeric Notch transcriptional complexes are required for T-cell maturation and leukemic transformation but are dispensable for T-cell fate specification from a multipotential precursor.
Mon Nov 01 00:00:00 EDT 2010
Dynamic macrophage "probing" is required for the efficient capture of phagocytic targets.
The Journal of cell biology
Flannagan RS,Harrison RE,Yip CM,Jaqaman K,Grinstein S
14-0114 was used in Flow cytometry/Cell sorting to investigate the process of ligand binding to immunoreceptors.
Mon Dec 13 00:00:00 EST 2010
Moderate oxygen augments lipopolysaccharide-induced lung injury in mice.
American journal of physiology. Lung cellular and molecular physiology
Aggarwal NR,D'Alessio FR,Tsushima K,Files DC,Damarla M,Sidhaye VK,Fraig MM,Polotsky VY,King LS
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2010
Potent anti-tumor responses to immunization with dendritic cells loaded with tumor tissue and an NKT cell ligand.
Immunology and cell biology
Petersen TR,Sika-Paotonu D,Knight DA,Dickgreber N,Farrand KJ,Ronchese F,Hermans IF
14-0114 was used in Flow cytometry/Cell sorting to investigate the impact of eliciting T-cell help from activated iNKT cells using alpha-galactosylceramide, showing potent anti-tumour response.
Thu Jul 01 00:00:00 EDT 2010
Recipient Toll-like receptors contribute to chronic graft dysfunction by both MyD88- and TRIF-dependent signaling.
Disease models & mechanisms
Wang S,Schmaderer C,Kiss E,Schmidt C,Bonrouhi M,Porubsky S,Gretz N,Schaefer L,Kirschning CJ,Popovic ZV,Gröne HJ
14-0114 was used in Flow cytometry/Cell sorting to test whether toll-like receptors influence chronic fibrosing inflammation.
Wed Mar 10 00:00:00 EST 2010
Cutting edge: adaptive versus innate receptor signals selectively control the pool sizes of murine IFN-γ- or IL-17-producing γδ T cells upon infection.
Journal of immunology (Baltimore, Md. : 1950)
Ribot JC,Chaves-Ferreira M,d'Orey F,Wencker M,Gonçalves-Sousa N,Decalf J,Simas JP,Hayday AC,Silva-Santos B
14-0114 was used in Flow cytometry/Cell sorting to investigate the properties of γδ T lymphocytes for adaptive and innate immunity.
Wed Dec 01 00:00:00 EST 2010
Expression of the chemokine binding protein M3 promotes marked changes in the accumulation of specific leukocytes subsets within the intestine.
Gastroenterology
Shang L,Thirunarayanan N,Viejo-Borbolla A,Martin AP,Bogunovic M,Marchesi F,Unkeless JC,Ho Y,Furtado GC,Alcami A,Merad M,Mayer L,Lira SA
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2009
Dendritic cells are crucial for maintenance of tertiary lymphoid structures in the lung of influenza virus-infected mice.
The Journal of experimental medicine
GeurtsvanKessel CH,Willart MA,Bergen IM,van Rijt LS,Muskens F,Elewaut D,Osterhaus AD,Hendriks R,Rimmelzwaan GF,Lambrecht BN
14-0114 was used in Immunohistochemistry to study the role of CD11c+ dendritic cells in tertiary lymphoid organs organisation.
Mon Oct 26 00:00:00 EDT 2009
Differential roles of migratory and resident DCs in T cell priming after mucosal or skin HSV-1 infection.
The Journal of experimental medicine
Lee HK,Zamora M,Linehan MM,Iijima N,Gonzalez D,Haberman A,Iwasaki A
14-0114 was used in Flow cytometry/Cell sorting to show that migrant and resident dendritic cells play an important role in priming CD8 and CD4 T cell responses, and their relative importance depends on the mode of infection in vivo.
Mon Feb 16 00:00:00 EST 2009
Migratory and antigen presentation functions of IFN-producing killer dendritic cells.
Cancer research
Himoudi N,Yan M,Bouma G,Morgenstern D,Wallace R,Seddon B,Buddle J,Eddaoudi A,Howe SJ,Cooper N,Anderson J
14-0114 was used in Flow cytometry/Cell sorting to study how BM-IKDCs are capable of cytotoxic killing of tumour targets, and also of potent antigen presentation after encountering antigen in the context of a viable target cell.
Sat Aug 15 00:00:00 EDT 2009
Tissue-resident macrophages protect the liver from ischemia reperfusion injury via a heme oxygenase-1-dependent mechanism.
Molecular therapy : the journal of the American Society of Gene Therapy
Devey L,Ferenbach D,Mohr E,Sangster K,Bellamy CO,Hughes J,Wigmore SJ
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2009
Murine epidermal Langerhans cells and langerin-expressing dermal dendritic cells are unrelated and exhibit distinct functions.
Proceedings of the National Academy of Sciences of the United States of America
Nagao K,Ginhoux F,Leitner WW,Motegi S,Bennett CL,Clausen BE,Merad M,Udey MC
14-0114 was used in Flow cytometry/Cell sorting to investigate the relationships between langerin(+) dendritic cells and Langerhans cells.
Tue Mar 03 00:00:00 EST 2009
Combination of all-trans retinoic acid and a human papillomavirus therapeutic vaccine suppresses the number and function of immature myeloid cells and enhances antitumor immunity.
Cancer science
Song X,Ye D,Liu B,Cui J,Zhao X,Yi L,Liang J,Song J,Zhang Z,Zhao Q
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Sun Feb 01 00:00:00 EST 2009
SIGNR1-negative red pulp macrophages protect against acute streptococcal sepsis after Leishmania donovani-induced loss of marginal zone macrophages.
The American journal of pathology
Kirby AC,Beattie L,Maroof A,van Rooijen N,Kaye PM
14-0114 was used in Flow cytometry/Cell sorting to show the protective activity of SIGNR1(+) marginal zone macrophages can be compensated for by activated red pulp macrophages.
Tue Sep 01 00:00:00 EDT 2009
Matrilysin (Matrix Metalloproteinase-7) regulates anti-inflammatory and antifibrotic pulmonary dendritic cells that express CD103 (alpha(E)beta(7)-integrin).
The American journal of pathology
Manicone AM,Huizar I,McGuire JK
14-0114 was used in Flow cytometry/Cell sorting to assess matrix metalloproteinase-7 effects on CD103-E-cadherin interactions in lung injury.
Tue Dec 01 00:00:00 EST 2009
Matrilysin (Matrix Metalloproteinase-7) regulates anti-inflammatory and antifibrotic pulmonary dendritic cells that express CD103 (alpha(E)beta(7)-integrin).
The American journal of pathology
Manicone AM,Huizar I,McGuire JK
14-0114 was used in Flow cytometry/Cell sorting to assess matrix metalloproteinase-7 effects on CD103-E-cadherin interactions in lung injury.
Tue Dec 01 00:00:00 EST 2009
Attenuation of AD-like neuropathology by harnessing peripheral immune cells: local elevation of IL-10 and MMP-9.
Journal of neurochemistry
Koronyo-Hamaoui M,Ko MK,Koronyo Y,Azoulay D,Seksenyan A,Kunis G,Pham M,Bakhsheshian J,Rogeri P,Black KL,Farkas DL,Schwartz M
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunofluorescence
Tue Dec 01 00:00:00 EST 2009
Attenuation of AD-like neuropathology by harnessing peripheral immune cells: local elevation of IL-10 and MMP-9.
Journal of neurochemistry
Koronyo-Hamaoui M,Ko MK,Koronyo Y,Azoulay D,Seksenyan A,Kunis G,Pham M,Bakhsheshian J,Rogeri P,Black KL,Farkas DL,Schwartz M
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunofluorescence
Tue Dec 01 00:00:00 EST 2009
Sialoadhesin-positive macrophages bind regulatory T cells, negatively controlling their expansion and autoimmune disease progression.
Journal of immunology (Baltimore, Md. : 1950)
Wu C,Rauch U,Korpos E,Song J,Loser K,Crocker PR,Sorokin LM
14-0114 was used in Flow cytometry/Cell sorting to propose a new direct cell-cell interaction-based mechanism regulating the expansion of Tregs during autoimmune and inflammatory processes.
Fri May 15 00:00:00 EDT 2009
Leptin receptor is expressed in thymus medulla and leptin protects against thymic remodeling during endotoxemia-induced thymus involution.
The Journal of endocrinology
Gruver AL,Ventevogel MS,Sempowski GD
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunofluorescence
Thu Oct 01 00:00:00 EDT 2009
TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.
Cellular immunology
Drage MG,Pecora ND,Hise AG,Febbraio M,Silverstein RL,Golenbock DT,Boom WH,Harding CV
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Jun 12 00:00:00 EDT 2009
Mycobacterium bovis BCG decreases MHC-II expression in vivo on murine lung macrophages and dendritic cells during aerosol infection.
Cellular immunology
Pecora ND,Fulton SA,Reba SM,Drage MG,Simmons DP,Urankar-Nagy NJ,Boom WH,Harding CV
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Jan 02 00:00:00 EST 2009
Peripheral dendritic cells are essential for both the innate and adaptive antiviral immune responses in the central nervous system.
Virology
Steel CD,Hahto SM,Ciavarra RP
14-0114-82 was used in Flow Cytometry to study the adaptive primary antiviral immune response in the CNS and the effect of dendritic cells upon this in vivo.
Sat Apr 25 00:00:00 EDT 2009
Enhancement of antitumor radiation efficacy and consistent induction of the abscopal effect in mice by ECI301, an active variant of macrophage inflammatory protein-1alpha.
Clinical cancer research : an official journal of the American Association for Cancer Research
Shiraishi K,Ishiwata Y,Nakagawa K,Yokochi S,Taruki C,Akuta T,Ohtomo K,Matsushima K,Tamatani T,Kanegasaki S
14-0114-82 was used in Immunohistochemistry (Frozen) to study whether intravenous administration of a chemokine after local tumour site irradiation can prevent remaining, as well as distant, non-irradiated tumour cell growth by leukocyte recruitment.
Fri Feb 15 00:00:00 EST 2008
Enhancement of antitumor radiation efficacy and consistent induction of the abscopal effect in mice by ECI301, an active variant of macrophage inflammatory protein-1alpha.
Clinical cancer research : an official journal of the American Association for Cancer Research
Shiraishi K,Ishiwata Y,Nakagawa K,Yokochi S,Taruki C,Akuta T,Ohtomo K,Matsushima K,Tamatani T,Kanegasaki S
14-0114-82 was used in Immunohistochemistry (Frozen) to study whether intravenous administration of a chemokine after local tumour site irradiation can prevent remaining, as well as distant, non-irradiated tumour cell growth by leukocyte recruitment.
Fri Feb 15 00:00:00 EST 2008
Dynamics of lung macrophage activation in response to helminth infection.
Journal of leukocyte biology
Siracusa MC,Reece JJ,Urban JF,Scott AL
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunofluorescence
Mon Dec 01 00:00:00 EST 2008
Down-regulation of dendritic cell signaling pathways by Leishmania amazonensis amastigotes.
Molecular immunology
Xin L,Li K,Soong L
14-0114 was used in Flow cytometry/Cell sorting to suggest that La parasites, especially in their intracellular forms, have evolved unique strategies to actively down-regulate early innate signalling events.
Tue Jul 01 00:00:00 EDT 2008
Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency.
Proceedings of the National Academy of Sciences of the United States of America
Porubsky S,Speak AO,Luckow B,Cerundolo V,Platt FM,Gröne HJ
14-0114 was used in Flow cytometry/Cell sorting to investigate the role of iGb3 in iNKT cell selection.
Tue Apr 03 00:00:00 EDT 2007
The mouse mammary carcinoma 4T1: characterization of the cellular landscape of primary tumours and metastatic tumour foci.
International journal of experimental pathology
DuPré SA,Redelman D,Hunter KW
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2007
Essential roles of DC-derived IL-15 as a mediator of inflammatory responses in vivo.
The Journal of experimental medicine
Ohteki T,Tada H,Ishida K,Sato T,Maki C,Yamada T,Hamuro J,Koyasu S
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunohistochemistry
Mon Oct 02 00:00:00 EDT 2006
Essential roles of DC-derived IL-15 as a mediator of inflammatory responses in vivo.
The Journal of experimental medicine
Ohteki T,Tada H,Ishida K,Sato T,Maki C,Yamada T,Hamuro J,Koyasu S
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Immunohistochemistry
Mon Oct 02 00:00:00 EDT 2006
Induction of robust immune responses against human immunodeficiency virus is supported by the inherent tropism of adeno-associated virus type 5 for dendritic cells.
Journal of virology
Xin KQ,Mizukami H,Urabe M,Toda Y,Shinoda K,Yoshida A,Oomura K,Kojima Y,Ichino M,Klinman D,Ozawa K,Okuda K
Published figure using CD11c monoclonal antibody (Product # 14-0114-82) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2006
The existence of CD11c+ sentinel and F4/80+ interstitial dendritic cells in dental pulp and their dynamics and functional properties.
International immunology
Zhang J,Kawashima N,Suda H,Nakano Y,Takano Y,Azuma M
Fri Sep 01 00:00:00 EDT 2006
