Invitrogen

CD11c Monoclonal Antibody (N418), Super Bright™ 600, eBioscience™

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Questions & Answers

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Antibody Testing Data (1)
Published Figures (43)

FIGURE: 1 / 44

CD11c Antibody (63-0114-82) in Flow

C57BL/6 mouse splenocytes were stained with CD45R (B220) Monoclonal Antibody, FITC (Product # 11-0452-82) and 0.06 µg of Armenian Hamster IgG Isotype Control, Super Bright 600 (Product # 63-4888-82) (left) or 0.06 µg of CD11c Monoclonal Antibody, Super Bright 600 (right). Total viable cells were used for analysis.

CD11c Antibody in Immunohistochemistry (IHC)

CD11c Antibody in Immunocytochemistry (ICC/IF)

CD11c Antibody in Immunohistochemistry, Flow Cytometry (IHC, Flow)

Product Image Gallery

Product Details

63-0114-82

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

View 8 publications 8 publications

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Flow Cytometry (Flow)

0.125 µg/test

View 42 publications 42 publications

Product Specifications

Species Reactivity

Mouse

Published species

Mouse

Host/Isotype

Armenian hamster / IgG

Recommended Isotype Control

Armenian Hamster IgG Isotype Control (eBio299Arm), Super Bright™ 600, eBioscience™

Class

Monoclonal

Type

Antibody

Clone

N418

Conjugate

Super Bright™ 600 Super Bright™ 600 Super Bright™ 600

Excitation/Emission Max

414/601 nm View spectra

Form

Liquid

Concentration

0.2 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2, with BSA

Contains

0.09% sodium azide

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2722930

Product Specific Information

Description: The N418 monoclonal antibody reacts with mouse CD11c, the integrin alphaX. CD11c non-covalently associates with beta2 integrin to form the CD11c/CD18 heterodimer. CD11c is expressed by dendritic cells, a subset of Intestinal Intraepithelial Lymphocytes (IEL) and some activated T cells. CD11c/CD18 binds to CD54, iC3b and fibrinogen and plays a role in leukocyte adhesive interactions. N418 binds to CD11c on splenic dendritic cells in the T-dependent areas of mouse spleen and precipitates a 150, 90 kDa heterodimer.

Applications Reported: This N418 antibody has been reported for use in flow cytometric analysis.

Applications Tested: This N418 antibody has been tested by flow cytometric analysis of mouse splenocytes. This may be used at less than or equal to 0.125 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Super Bright 600 is a tandem dye that can be excited with the violet laser line (405 nm) and emits at 600 nm. We recommend using a 610/20 bandpass filter. Please make sure that your instrument is capable of detecting this fluorochrome.

When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Complete Staining Buffer (Product # SB-4401) to minimize any non-specific polymer interactions. Please refer to the datasheet for Super Bright Staining Buffer for more information.

Light sensitivity: This tandem dye is sensitive to photo-induced oxidation. Please protect this vial and stained samples from light.

Fixation: Samples can be stored in IC Fixation Buffer (Product # 00-8222) (100 µL of cell sample + 100 µL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (Product # 00-5333) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically.

Excitation: 405 nm; Emission: 600 nm; Laser: Violet Laser

Super Bright Polymer Dyes are sold under license from Becton, Dickinson and Company.

Target Information

CD11, along with CD18, form a heterodimer adhesion molecule. In particular, CD11 is composed of CD11a, CD11b and CD11c. CD11a is a leukocyte marker that is expressed in B and T lymphocytes, macrophages, monocytes, neutrophils, basophils and eosinophils. CD11b is primarily expressed by monocytes, macrophages, natural killer cells, some B and T-cells, and granulocytes. CD11c is expressed in monocytes, macrophages, natural killer cells, some granulocytes and less so in a subset of lymphocytes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Product References

Toxin expression during Staphylococcus aureus infection imprints host immunity to inhibit vaccine efficacy.

NPJ vaccines

Teymournejad O,Li Z,Beesetty P,Yang C,Montgomery CP

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Tue Jan 24 00:00:00 EST 2023

Topical Diacerein Decreases Skin and Splenic CD11c⁺ Dendritic Cells in Psoriasis.

International journal of molecular sciences

Brunner SM,Ramspacher A,Rieser C,Leitner J,Heil H,Ablinger M,Tevini J,Wimmer M,Koller A,Piñón Hofbauer J,Felder TK,Bauer JW,Kofler B,Lang R,Wally V

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Tue Feb 21 00:00:00 EST 2023

Outer Membrane Vesicle-Coated Nanoparticle Vaccine Protects Against Acinetobacter baumannii Pneumonia and Sepsis.

Advanced nanobiomed research

Bjanes E,Zhou J,Qayum T,Krishnan N,Zurich RH,Menon ND,Hoffman A,Fang RH,Zhang L,Nizet V

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Wed Feb 01 00:00:00 EST 2023

CD11c⁺ microglia promote white matter repair after ischemic stroke.

Cell death & disease

Jia J,Zheng L,Ye L,Chen J,Shu S,Xu S,Bao X,Xia S,Liu R,Xu Y,Zhang M

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Fri Feb 24 00:00:00 EST 2023

Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2023

P. gingivalis Infection Upregulates PD-L1 Expression on Dendritic Cells, Suppresses CD8+ T-cell Responses, and Aggravates Oral Cancer.

Cancer immunology research

Ren J,Han X,Lohner H,Hoyle RG,Li J,Liang S,Wang H

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2023

Inhibition of Macrophage-Specific CHIT1 as an Approach to Treat Airway Remodeling in Severe Asthma.

International journal of molecular sciences

Sklepkiewicz P,Dymek B,Mlacki M,Zagozdzon A,Salamon M,Siwińska AM,Mazurkiewicz MP,de Souza Xavier Costa N,Mazur M,Mauad T,Gołębiowski A,Dzwonek K,Gołąb J,Zasłona Z

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2023

Targeted inhibition of osteoclastogenesis reveals the pathogenesis and therapeutics of bone loss under sympathetic neurostress.

International journal of oral science

Sui B,Liu J,Zheng C,Dang L,Chen J,Cao Y,Zhang K,Liu L,Dang M,Zhang L,Chen N,He T,Xuan K,Jin F,Zhang G,Jin Y,Hu C

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Immunohistochemistry

Mon Aug 01 00:00:00 EDT 2022

Meningeal lymphatic drainage promotes T cell responses against Toxoplasma gondii but is dispensable for parasite control in the brain.

eLife

Kovacs MA,Cowan MN,Babcock IW,Sibley LA,Still K,Batista SJ,Labuzan SA,Sethi I,Harris TH

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Wed Dec 21 00:00:00 EST 2022

Interferon-γ Stimulates Interleukin-27 Derived from Dendritic Cells to Regulate Th9 Differentiation through STAT1/3 Pathway.

Disease markers

Xiong P,Liu T,Chen Y,Xu Q,Hu X,Han F,Shi L

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Mon Oct 31 00:00:00 EDT 2022

Neutrophil-dendritic cell interaction plays an important role in live attenuated Leishmania vaccine induced immunity.

PLoS neglected tropical diseases

Bhattacharya P,Ismail N,Saxena A,Gannavaram S,Dey R,Oljuskin T,Akue A,Takeda K,Yu J,Karmakar S,Dagur PK,McCoy JP,Nakhasi HL

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Tue Feb 01 00:00:00 EST 2022

Self-Tolerance of Vascular Tissues Is Broken Down by Vascular Dendritic Cells in Response to Systemic Inflammation to Initiate Regional Autoinflammation.

Frontiers in immunology

Sun L,Zhang W,Zhao L,Zhao Y,Wang F,Lew AM,Xu Y

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Immunohistochemistry

Fri Apr 01 00:00:00 EDT 2022

Nucleolin Therapeutic Targeting Decreases Pancreatic Cancer Immunosuppression.

Cancers

Ponzo M,Debesset A,Cossutta M,Chalabi-Dchar M,Houppe C,Pilon C,Nicolas-Boluda A,Meunier S,Raineri F,Thiolat A,Nicolle R,Maione F,Brundu S,Cojocaru CF,Bouvet P,Bousquet C,Gazeau F,Tournigand C,Courty J,Giraudo E,Cohen JL,Cascone I

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Wed Aug 31 00:00:00 EDT 2022

Single-cell transcriptomics reveals distinct cell response between acute and chronic pulmonary infection of Pseudomonas aeruginosa.

MedComm

Hu X,Wu M,Ma T,Zhang Y,Zou C,Wang R,Zhang Y,Ren Y,Li Q,Liu H,Li H,Wang T,Sun X,Yang Y,Tang M,Li X,Li J,Gao X,Li T,Zhou X

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Immunohistochemistry

Thu Dec 01 00:00:00 EST 2022

Neutrophil-specific gain-of-function mutations in Nlrp3 promote development of cryopyrin-associated periodic syndrome.

The Journal of experimental medicine

Stackowicz J,Gaudenzio N,Serhan N,Conde E,Godon O,Marichal T,Starkl P,Balbino B,Roers A,Bruhns P,Jönsson F,Moguelet P,Georgin-Lavialle S,Broderick L,Hoffman HM,Galli SJ,Reber LL

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Immunohistochemistry

Mon Oct 04 00:00:00 EDT 2021

Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin.

Cell death and differentiation

Velletri T,Huang Y,Wang Y,Li Q,Hu M,Xie N,Yang Q,Chen X,Chen Q,Shou P,Gan Y,Candi E,Annicchiarico-Petruzzelli M,Agostini M,Yang H,Melino G,Shi Y,Wang Y

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Fri Jan 01 00:00:00 EST 2021

Depletion of Adipocyte Becn1 Leads to Lipodystrophy and Metabolic Dysregulation.

Diabetes

Jin Y,Ji Y,Song Y,Choe SS,Jeon YG,Na H,Nam TW,Kim HJ,Nahmgoong H,Kim SM,Kim JW,Nam KT,Seong JK,Hwang D,Park CB,Lee IH,Kim JB,Lee HW

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Fri Jan 01 00:00:00 EST 2021

Depletion of Adipocyte Becn1 Leads to Lipodystrophy and Metabolic Dysregulation.

Diabetes

Jin Y,Ji Y,Song Y,Choe SS,Jeon YG,Na H,Nam TW,Kim HJ,Nahmgoong H,Kim SM,Kim JW,Nam KT,Seong JK,Hwang D,Park CB,Lee IH,Kim JB,Lee HW

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Fri Jan 01 00:00:00 EST 2021

Induction of IL-12p40 and type 1 immunity by Toxoplasma gondii in the absence of the TLR-MyD88 signaling cascade.

PLoS pathogens

Snyder LM,Doherty CM,Mercer HL,Denkers EY

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Fri Oct 01 00:00:00 EDT 2021

Pancreatic Cancer Chemotherapy Is Potentiated by Induction of Tertiary Lymphoid Structures in Mice.

Cellular and molecular gastroenterology and hepatology

Delvecchio FR,Fincham REA,Spear S,Clear A,Roy-Luzarraga M,Balkwill FR,Gribben JG,Bombardieri M,Hodivala-Dilke K,Capasso M,Kocher HM

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Mon Mar 28 00:00:00 EDT 2022

T cell-derived tumor necrosis factor induces cytotoxicity by activating RIPK1-dependent target cell death.

JCI insight

Chun N,Ang RL,Chan M,Fairchild RL,Baldwin WM,Horwitz JK,Gelles JD,Chipuk JE,Kelliher MA,Pavlov VI,Li Y,Homann D,Heeger PS,Ting AT

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Wed Dec 22 00:00:00 EST 2021

STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.

Cellular and molecular gastroenterology and hepatology

Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Mon Jan 24 00:00:00 EST 2022

Intratumoral injection of TLR9 agonist promotes an immunopermissive microenvironment transition and causes cooperative antitumor activity in combination with anti-PD1 in pancreatic cancer.

Journal for immunotherapy of cancer

Carbone C,Piro G,Agostini A,Delfino P,De Sanctis F,Nasca V,Spallotta F,Sette C,Martini M,Ugel S,Corbo V,Cappello P,Bria E,Scarpa A,Tortora G

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Wed Sep 01 00:00:00 EDT 2021

Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition.

Cell reports

Stephens WZ,Kubinak JL,Ghazaryan A,Bauer KM,Bell R,Buhrke K,Chiaro TR,Weis AM,Tang WW,Monts JK,Soto R,Ekiz HA,O'Connell RM,Round JL

63-0114-82 was used in Flow cytometry/Cell sorting to demonstrate a role for IEC-derived MHC class II in constraining microbiota composition and inducing tolerogenic responses against it.

Tue Nov 02 00:00:00 EDT 2021

Mesenchymal stem cells attenuate liver fibrosis by targeting Ly6C^hi/lo macrophages through activating the cytokine-paracrine and apoptotic pathways.

Cell death discovery

Li YH,Shen S,Shao T,Jin MT,Fan DD,Lin AF,Xiang LX,Shao JZ

63-0114-82 was used in Flow Cytometry to provide insights into the functional role of bone marrow-derived sesenchymal stem cell in alleviating liver fibrosis.

Mon Sep 13 00:00:00 EDT 2021

Dual-Wavelength Photosensitive Nano-in-Micro Scaffold Regulates Innate and Adaptive Immune Responses for Osteogenesis.

Nano-micro letters

Zhao Q,Shi M,Yin C,Zhao Z,Zhang J,Wang J,Shen K,Zhang L,Tang H,Xiao Y,Zhang Y

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Sat Nov 21 00:00:00 EST 2020

Dual-Wavelength Photosensitive Nano-in-Micro Scaffold Regulates Innate and Adaptive Immune Responses for Osteogenesis.

Nano-micro letters

Zhao Q,Shi M,Yin C,Zhao Z,Zhang J,Wang J,Shen K,Zhang L,Tang H,Xiao Y,Zhang Y

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Sat Nov 21 00:00:00 EST 2020

Glufosinate constrains synchronous and metachronous metastasis by promoting anti-tumor macrophages.

EMBO molecular medicine

Menga A,Serra M,Todisco S,Riera-Domingo C,Ammarah U,Ehling M,Palmieri EM,Di Noia MA,Gissi R,Favia M,Pierri CL,Porporato PE,Castegna A,Mazzone M

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Wed Oct 07 00:00:00 EDT 2020

Glufosinate constrains synchronous and metachronous metastasis by promoting anti-tumor macrophages.

EMBO molecular medicine

Menga A,Serra M,Todisco S,Riera-Domingo C,Ammarah U,Ehling M,Palmieri EM,Di Noia MA,Gissi R,Favia M,Pierri CL,Porporato PE,Castegna A,Mazzone M

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Wed Oct 07 00:00:00 EDT 2020

Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.

British journal of pharmacology

De Cicco P,Ercolano G,Rubino V,Terrazzano G,Ruggiero G,Cirino G,Ianaro A

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Sat Feb 01 00:00:00 EST 2020

Mycobacterium tuberculosis-infected alveolar epithelial cells modulate dendritic cell function through the HIF-1α-NOS2 axis.

Journal of leukocyte biology

Rodrigues TS,Alvarez ARP,Gembre AF,Forni MFPAD,de Melo BMS,Alves Filho JCF,Câmara NOS,Bonato VLD

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Thu Oct 01 00:00:00 EDT 2020

RIG-I Promotes Cell Death in Hepatocellular Carcinoma by Inducing M1 Polarization of Perineal Macrophages Through the RIG-I/MAVS/NF-κB Pathway.

OncoTargets and therapy

Zhou B,Li C,Yang Y,Wang Z

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Sun Apr 17 00:00:00 EDT 2022

Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells.

Nature communications

Lucas B,White AJ,Cosway EJ,Parnell SM,James KD,Jones ND,Ohigashi I,Takahama Y,Jenkinson WE,Anderson G

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Mon May 04 00:00:00 EDT 2020

Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement.

eLife

Kalinski AL,Yoon C,Huffman LD,Duncker PC,Kohen R,Passino R,Hafner H,Johnson C,Kawaguchi R,Carbajal KS,Jara JS,Hollis E,Geschwind DH,Segal BM,Giger RJ

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Wed Dec 02 00:00:00 EST 2020

CD103⁺ cDC1 and endogenous CD8⁺ T cells are necessary for improved CD40L-overexpressing CAR T cell antitumor function.

Nature communications

Kuhn NF,Lopez AV,Li X,Cai W,Daniyan AF,Brentjens RJ

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Wed Dec 02 00:00:00 EST 2020

Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.

JCI insight

Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Thu Aug 20 00:00:00 EDT 2020

Bone metastasis is associated with acquisition of mesenchymal phenotype and immune suppression in a model of spontaneous breast cancer metastasis.

Scientific reports

Monteran L,Ershaid N,Sabah I,Fahoum I,Zait Y,Shani O,Cohen N,Eldar-Boock A,Satchi-Fainaro R,Erez N

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Fri Aug 14 00:00:00 EDT 2020

Hepatocytes trap and silence coxsackieviruses, protecting against systemic disease in mice.

Communications biology

Kimura T,Flynn CT,Whitton JL

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Fri Oct 16 00:00:00 EDT 2020

Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming.

Cell reports

McDaniel MM,Kottyan LC,Singh H,Pasare C

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Tue May 05 00:00:00 EDT 2020

CNS Immune Profiling in a Dengue Virus-Infected Immunocompetent Outbred ICR Mice Strain.

Frontiers in cellular and infection microbiology

Shen TJ,Chen CL,Jhan MK,Tseng PC,Lin CF

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Thu Jun 17 00:00:00 EDT 2021

Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity.

Nature communications

Toubal A,Kiaf B,Beaudoin L,Cagninacci L,Rhimi M,Fruchet B,da Silva J,Corbett AJ,Simoni Y,Lantz O,Rossjohn J,McCluskey J,Lesnik P,Maguin E,Lehuen A

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Fri Jul 24 00:00:00 EDT 2020

An Nfil3-Zeb2-Id2 pathway imposes Irf8 enhancer switching during cDC1 development.

Nature immunology

Bagadia P,Huang X,Liu TT,Durai V,Grajales-Reyes GE,Nitschké M,Modrusan Z,Granja JM,Satpathy AT,Briseño CG,Gargaro M,Iwata A,Kim S,Chang HY,Shaw AS,Murphy TL,Murphy KM

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Sun Sep 01 00:00:00 EDT 2019

Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population.

Cell reports

Leylek R,Alcántara-Hernández M,Lanzar Z,Lüdtke A,Perez OA,Reizis B,Idoyaga J

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Tue Dec 10 00:00:00 EST 2019

Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.

Cell

Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Thu Jun 28 00:00:00 EDT 2018

Macrophage Depletion Protects against Cigarette Smoke-Induced Inflammatory Response in the Mouse Colon and Lung.

Frontiers in physiology

Lim D,Kim W,Lee C,Bae H,Kim J

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Wed Sep 30 00:00:00 EDT 2020

RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease.

EMBO molecular medicine

Zhu H,Lou F,Yin Q,Gao Y,Sun Y,Bai J,Xu Z,Liu Z,Cai W,Ke F,Zhang L,Zhou H,Wang H,Wang G,Chen X,Zhang H,Wang Z,Ginhoux F,Lu C,Su B,Wang H

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Mon May 01 00:00:00 EDT 2017

The Second-Generation PGI2 Analogue Treprostinil Fails to Chemoprevent Tumors in a Murine Lung Adenocarcinoma Model.

Cancer prevention research (Philadelphia, Pa.)

Dwyer-Nield L,Hickey GA,Friedman M,Choo K,McArthur DG,Tennis MA,New ML,Geraci M,Keith RL

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Wed Nov 01 00:00:00 EDT 2017

CD11c+ resident macrophages drive hepatocyte death-triggered liver fibrosis in a murine model of nonalcoholic steatohepatitis.

JCI insight

Itoh M,Suganami T,Kato H,Kanai S,Shirakawa I,Sakai T,Goto T,Asakawa M,Hidaka I,Sakugawa H,Ohnishi K,Komohara Y,Asano K,Sakaida I,Tanaka M,Ogawa Y

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Immunohistochemistry

Thu Nov 16 00:00:00 EST 2017

Identification of a Hematopoietic Cell Dedifferentiation-Inducing Factor.

Journal of cellular physiology

Li Y,Adomat H,Guns ET,Hojabrpour P,Duronio V,Curran TA,Jalili RB,Jia W,Delwar Z,Zhang Y,Elizei SS,Ghahary A

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Immunocytochemistry

Wed Jun 01 00:00:00 EDT 2016

High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity.

Nature

Schulz MD,Atay C,Heringer J,Romrig FK,Schwitalla S,Aydin B,Ziegler PK,Varga J,Reindl W,Pommerenke C,Salinas-Riester G,Böck A,Alpert C,Blaut M,Polson SC,Brandl L,Kirchner T,Greten FR,Polson SW,Arkan MC

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Thu Oct 23 00:00:00 EDT 2014

P2X7 receptor modulates inflammatory and functional pulmonary changes induced by silica.

PloS one

Monção-Ribeiro LC,Faffe DS,Santana PT,Vieira FS,da Graça CL,Marques-da-Silva C,Machado MN,Caruso-Neves C,Zin WA,Borojevic R,Takiya CM,Coutinho-Silva R

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Flow Cytometry

Thu Sep 17 00:00:00 EDT 2015

Leptin receptor is expressed in thymus medulla and leptin protects against thymic remodeling during endotoxemia-induced thymus involution.

The Journal of endocrinology

Gruver AL,Ventevogel MS,Sempowski GD

Published figure using CD11c monoclonal antibody (Product # 63-0114-82) in Immunocytochemistry

Thu Oct 01 00:00:00 EDT 2009

Bioinformatics

Protein Aliases: CD11 antigen-like family member C; CD11c; CD11C (p150) alpha polypeptide; complement receptor 4; Integrin alpha-X; integrin aX; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95

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Gene Aliases: AI449405; Cd11c; Cr4; Itgax; N418

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UniProt ID: (Mouse) Q9QXH4

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Entrez Gene ID: (Mouse) 16411

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Function(s)

metal ion binding integrin

Process(es)

cell adhesion integrin-mediated signaling pathway heterotypic cell-cell adhesion activated T cell proliferation defense response to virus positive regulation of protein targeting to mitochondrion

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CD11c Monoclonal Antibody (N418), Super Bright™ 600, eBioscience™

CD11c Antibody (63-0114-82) in Flow

Product Details

63-0114-82

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Species Reactivity

Published species

Host/Isotype

Recommended Isotype Control

Class

Type

Clone

Conjugate

Excitation/Emission Max

Form

Concentration

Purification

Storage buffer

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