Product References
TGFβ1+CCR5+ neutrophil subset increases in bone marrow and causes age-related osteoporosis in male mice.
Nature communications
Li J,Yao Z,Liu X,Duan R,Yi X,Ayoub A,Sanders JO,Mesfin A,Xing L,Boyce BF
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Wed Jan 11 00:00:00 EST 2023
Sympathetic Nerves Coordinate Corneal Epithelial Wound Healing by Controlling the Mobilization of Ly6Chi Monocytes From the Spleen to the Injured Cornea.
Investigative ophthalmology & visual science
He S,Liu J,Xue Y,Fu T,Li Z
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2023
Intranasal Delivery of Endothelial Cell-Derived Extracellular Vesicles with Supramolecular Gel Attenuates Myocardial Ischemia-Reperfusion Injury.
International journal of nanomedicine
Wang J,Tan Y,Dai Y,Hu K,Tan X,Jiang S,Li G,Zhang X,Kang L,Wang X,Xu B
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Thu Oct 05 00:00:00 EDT 2023
High body temperature increases gut microbiota-dependent host resistance to influenza A virus and SARS-CoV-2 infection.
Nature communications
Nagai M,Moriyama M,Ishii C,Mori H,Watanabe H,Nakahara T,Yamada T,Ishikawa D,Ishikawa T,Hirayama A,Kimura I,Nagahara A,Naito T,Fukuda S,Ichinohe T
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Fri Jun 30 00:00:00 EDT 2023
Differential requirement of neutralizing antibodies and T cells on protective immunity to SARS-CoV-2 variants of concern.
NPJ vaccines
Azevedo PO,Hojo-Souza NS,Faustino LP,Fumagalli MJ,Hirako IC,Oliveira ER,Figueiredo MM,Carvalho AF,Doro D,Benevides L,Durigon E,Fonseca F,Machado AM,Fernandes AP,Teixeira SR,Silva JS,Gazzinelli RT
48-5932-82 was used in Flow cytometry/Cell sorting to evaluate the efficacy of a Spike-based DNA vaccine (pCTV-WS) for protection against different VOCs using existing pre-clinical models of severe and moderate COVID-19.
Mon Feb 13 00:00:00 EST 2023
Impaired PPARγ activation by cadmium exacerbates infection-induced lung injury.
JCI insight
Larson-Casey JL,Liu S,Pyles JM,Lapi SE,Saleem K,Antony VB,Gonzalez ML,Crossman DK,Carter AB
48-5932-82 was used in Flow cytometry/Cell sorting to suggest that impaired activation of PPAR? in monocyte-derived macrophages exacerbates lung injury and the severity of LRTIs.
Mon May 08 00:00:00 EDT 2023
Macrophagic AMPKα1 orchestrates regenerative inflammation induced by glucocorticoids.
EMBO reports
Caratti G,Desgeorges T,Juban G,Stifel U,Fessard A,Koenen M,Caratti B,Théret M,Skurk C,Chazaud B,Tuckermann JP,Mounier R
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Mon Feb 06 00:00:00 EST 2023
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches.
Cell
Guilliams M,Bonnardel J,Haest B,Vanderborght B,Wagner C,Remmerie A,Bujko A,Martens L,Thoné T,Browaeys R,De Ponti FF,Vanneste B,Zwicker C,Svedberg FR,Vanhalewyn T,Gonçalves A,Lippens S,Devriendt B,Cox E,Ferrero G,Wittamer V,Willaert A,Kaptein SJF,Neyts J,Dallmeier K,Geldhof P,Casaert S,Deplancke B,Ten Dijke P,Hoorens A,Vanlander A,Berrevoet F,Van Nieuwenhove Y,Saeys Y,Saelens W,Van Vlierberghe H,Devisscher L,Scott CL
48-5932-82 was used in Flow cytometry/Cell sorting to demonstrate that LAMs are induced by local lipid exposure, leading to their induction in steatotic regions of the murine and human liver, while Kupffer cell development crucially depends on their cross-talk with hepatic stellate cells via the evolutionarily conserved ALK1-BMP9/10 axis.
Thu Jan 20 00:00:00 EST 2022
The NKCC1 ion transporter modulates microglial phenotype and inflammatory response to brain injury in a cell-autonomous manner.
PLoS biology
Tóth K,Lénárt N,Berki P,Fekete R,Szabadits E,Pósfai B,Cserép C,Alatshan A,Benkő S,Kiss D,Hübner CA,Gulyás A,Kaila K,Környei Z,Dénes Á
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2022
Gene-dosage effect of Pfkfb3 on monocyte/macrophage biology in atherosclerosis.
British journal of pharmacology
Guo S,Li A,Fu X,Li Z,Cao K,Song M,Huang S,Li Z,Yan J,Wang L,Dai X,Feng D,Wang Y,He J,Huo Y,Xu Y
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2022
Mineralocorticoid receptor antagonists and glucocorticoids differentially affect skeletal muscle inflammation and pathology in muscular dystrophy.
JCI insight
Howard ZM,Gomatam CK,Rabolli CP,Lowe J,Piepho AB,Bansal SS,Accornero F,Rafael-Fortney JA
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Mon Oct 10 00:00:00 EDT 2022
Therapeutic CFTR Correction Normalizes Systemic and Lung-Specific S1P Level Alterations Associated with Heart Failure.
International journal of molecular sciences
Uhl FE,Vanherle L,Matthes F,Meissner A
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Fri Jan 14 00:00:00 EST 2022
Tumor Growth Remains Refractory to Myc Ablation in Host Macrophages.
Cells
Morrow RJ,Allam AH,Konecnik J,Baloyan D,Dijkstra C,Eissmann MF,Jacob SP,O'Brien M,Poh AR,Ernst M
48-5932-82 was used in Flow cytometry/Cell sorting to benchmark Myc inactivation in tumor cells against the contribution of its expression in myeloid cells of murine hosts that harbor endogenous or allograft tumors.
Sat Dec 17 00:00:00 EST 2022
Monocarboxylate transporter 1 deficiency impacts CD8+ T lymphocytes proliferation and recruitment to adipose tissue during obesity.
iScience
Macchi C,Moregola A,Greco MF,Svecla M,Bonacina F,Dhup S,Dadhich RK,Audano M,Sonveaux P,Mauro C,Mitro N,Ruscica M,Norata GD
48-5932-82 was used in Flow cytometry/Cell sorting to highlight a distinct effect of MCT1 deficiency in CD8+ T cells in the crosstalk with adipocytes and reinforce the concept that targeting immunometabolic reprogramming in lymphocyte could impact the immune-adipose tissue axis in obesity.
Fri Jun 17 00:00:00 EDT 2022
A novel ZsGreen knock-in melanoma cell line reveals the function of CD11b in tumor phagocytosis.
Immunology and cell biology
Zhang L,Feng X,Shen Y,Wang Y,Liu Z,Ma Y,Gu Y,Guo G,Duan L,Lu L,Liang Y,Lawrence T,Huang R
48-5932-82 was used in Flow cytometry/Cell sorting to demonstrate that the ZsGreen-expressing YUMM1.7 melanoma model provides a valuable tool for the study of phagocytosis in vivo.
Sat Oct 01 00:00:00 EDT 2022
Therapeutic inhibition of the SRC-kinase HCK facilitates T cell tumor infiltration and improves response to immunotherapy.
Science advances
Poh AR,Love CG,Chisanga D,Steer JH,Baloyan D,Chopin M,Nutt S,Rautela J,Huntington ND,Etemadi N,O'Brien M,O'Keefe R,Ellies LG,Macri C,Mintern JD,Whitehead L,Gangadhara G,Boon L,Chand AL,Lowell CA,Shi W,Pixley FJ,Ernst M
48-5932-82 was used in Flow cytometry/Cell sorting to suggest that therapeutic targeting of HCK activity enhances response to immunotherapy by simultaneously stimulating immune cell activation and inhibiting the immunosuppressive tumor microenvironment.
Fri Jun 24 00:00:00 EDT 2022
Myeloid mineralocorticoid receptors contribute to skeletal muscle repair in muscular dystrophy and acute muscle injury.
American journal of physiology. Cell physiology
Howard ZM,Rastogi N,Lowe J,Hauck JS,Ingale P,Gomatam C,Gomez-Sanchez CE,Gomez-Sanchez EP,Bansal SS,Rafael-Fortney JA
48-5932-82 was used in Flow cytometry/Cell sorting to support important contributions of myeloid MR signaling to skeletal muscle repair in acute and chronic injuries and highlight the useful information gained from cell-specific genetic knockouts to delineate mechanisms of pharmacological efficacy.
Tue Mar 01 00:00:00 EST 2022
Mucosal fungi promote gut barrier function and social behavior via Type 17 immunity.
Cell
Leonardi I,Gao IH,Lin WY,Allen M,Li XV,Fiers WD,De Celie MB,Putzel GG,Yantiss RK,Johncilla M,Colak D,Iliev ID
48-5932-82 was used in Flow cytometry/Cell sorting to characterize the mycobiota biogeography along the gastrointestinal tract and identified a subset of fungi associated with the intestinal mucosa of mice and humans.
Thu Mar 03 00:00:00 EST 2022
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Monocyte Subsets With High Osteoclastogenic Potential and Their Epigenetic Regulation Orchestrated by IRF8.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Das A,Wang X,Kang J,Coulter A,Shetty AC,Bachu M,Brooks SR,Dell'Orso S,Foster BL,Fan X,Ozato K,Somerman MJ,Thumbigere-Math V
48-5932-82 was used in Flow Cytometry to provide novel insights into the transcription factors and active cis-regulatory elements that regulate OC differentiation.
Fri Jan 01 00:00:00 EST 2021
Pancreatic Cancer Chemotherapy Is Potentiated by Induction of Tertiary Lymphoid Structures in Mice.
Cellular and molecular gastroenterology and hepatology
Delvecchio FR,Fincham REA,Spear S,Clear A,Roy-Luzarraga M,Balkwill FR,Gribben JG,Bombardieri M,Hodivala-Dilke K,Capasso M,Kocher HM
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Mon Mar 28 00:00:00 EDT 2022
Disrupted Iron Metabolism and Mortality during Co-infection with Malaria and an Intestinal Gram-Negative Extracellular Pathogen.
Cell reports
Dos Santos LI,Torres TA,Diniz SQ,Gonçalves R,Caballero-Flores G,Núñez G,Gazzinelli RT,Maloy KJ,Ribeiro do V Antonelli L
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Myeloid DJ-1 deficiency protects acetaminophen-induced acute liver injury through decreasing inflammatory response.
Aging
Wang B,Li J,Jiao J,Xu M,Luo Y,Wang F,Xia Q,Gao Y,Feng Y,Kong X,Sun X
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Wed Jul 21 00:00:00 EDT 2021
NOX4 regulates macrophage apoptosis resistance to induce fibrotic progression.
The Journal of biological chemistry
Larson-Casey JL,Gu L,Kang J,Dhyani A,Carter AB
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Thu Jul 01 00:00:00 EDT 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
Abraxane-induced bone marrow CD11b+ myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with 64Cu-labeled anti-CD11b and prevented by anti-CSF-1.
Theranostics
Cao Q,Huang Q,Wang YA,Li C
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Fri Jul 23 00:00:00 EDT 2021
Inflammatory resolution and vascular barrier restoration after retinal ischemia reperfusion injury.
Journal of neuroinflammation
Abcouwer SF,Shanmugam S,Muthusamy A,Lin CM,Kong D,Hager H,Liu X,Antonetti DA
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Thu Aug 26 00:00:00 EDT 2021
Expanded renal lymphatics improve recovery following kidney injury.
Physiological reports
Baranwal G,Creed HA,Black LM,Auger A,Quach AM,Vegiraju R,Eckenrode HE,Agarwal A,Rutkowski JM
48-5932-82 was used in Flow cytometry/Cell sorting to demonstrate that increased lymphatic density prior to injury alters the injury recovery response and affords protection from CKD progression.
Mon Nov 01 00:00:00 EDT 2021
Roles of lung-recruited monocytes and pulmonary Vascular Endothelial Growth Factor (VEGF) in resolving Ventilator-Induced Lung Injury (VILI).
PloS one
Lin CK,Huang TH,Yang CT,Shi CS
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver.
Immunity
Remmerie A,Martens L,Thoné T,Castoldi A,Seurinck R,Pavie B,Roels J,Vanneste B,De Prijck S,Vanhockerhout M,Binte Abdul Latib M,Devisscher L,Hoorens A,Bonnardel J,Vandamme N,Kremer A,Borghgraef P,Van Vlierberghe H,Lippens S,Pearce E,Saeys Y,Scott CL
48-5932 was used in Flow cytometry/Cell sorting to highlight considerable heterogeneity within the macrophage pool and suggest a need for more specific macrophage targeting strategies in metabolic-associated fatty liver disease (MAFLD).
Tue Sep 15 00:00:00 EDT 2020
Plaque-associated myeloid cells derive from resident microglia in an Alzheimer's disease model.
The Journal of experimental medicine
Reed-Geaghan EG,Croxford AL,Becher B,Landreth GE
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Mon Apr 06 00:00:00 EDT 2020
Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease.
Brain : a journal of neurology
Koronyo-Hamaoui M,Sheyn J,Hayden EY,Li S,Fuchs DT,Regis GC,Lopes DHJ,Black KL,Bernstein KE,Teplow DB,Fuchs S,Koronyo Y,Rentsendorj A
48-5932 was used in Flow cytometry/Cell sorting to explore the impact of selective and transient angiotensin-converting enzyme overexpression on macrophage behaviour and the relative contribution of bone marrow-derived ACE10 macrophages, but not microglia, in attenuating disease progression.
Wed Jan 01 00:00:00 EST 2020
Proenkephalin+ regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function.
Proceedings of the National Academy of Sciences of the United States of America
Shime H,Odanaka M,Tsuiji M,Matoba T,Imai M,Yasumizu Y,Uraki R,Minohara K,Watanabe M,Bonito AJ,Fukuyama H,Ohkura N,Sakaguchi S,Morita A,Yamazaki S
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Tue Aug 25 00:00:00 EDT 2020
IgE Contributes to Atherosclerosis and Obesity by Affecting Macrophage Polarization, Macrophage Protein Network, and Foam Cell Formation.
Arteriosclerosis, thrombosis, and vascular biology
Zhang X,Li J,Luo S,Wang M,Huang Q,Deng Z,de Febbo C,Daoui A,Liew PX,Sukhova GK,Metso J,Jauhiainen M,Shi GP,Guo J
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2020
Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.
British journal of pharmacology
De Cicco P,Ercolano G,Rubino V,Terrazzano G,Ruggiero G,Cirino G,Ianaro A
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
Temporospatial distribution and transcriptional profile of retinal microglia in the oxygen-induced retinopathy mouse model.
Glia
Boeck M,Thien A,Wolf J,Hagemeyer N,Laich Y,Yusuf D,Backofen R,Zhang P,Boneva S,Stahl A,Hilgendorf I,Agostini H,Prinz M,Wieghofer P,Schlunck G,Schlecht A,Lange C
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2020
CCR2 deficiency in monocytes impairs angiogenesis and functional recovery after ischemic stroke in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Pedragosa J,Miró-Mur F,Otxoa-de-Amezaga A,Justicia C,Ruíz-Jaén F,Ponsaerts P,Pasparakis M,Planas AM
48-5932-82 was used in Flow Cytometry to suggest that pro-reparative monocyte subsets promote functional recovery after ischemic stroke.
Tue Dec 01 00:00:00 EST 2020
Characterization and regulation of osteoclast precursors following chronic Porphyromonas gingivalis infection.
Journal of leukocyte biology
Zhao Y,Li Z,Su L,Ballesteros-Tato A,Katz J,Michalek SM,Feng X,Zhang P
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Antitumor Effect and Immune Response of Nanosecond Pulsed Electric Fields in Pancreatic Cancer.
Frontiers in oncology
Zhao J,Chen S,Zhu L,Zhang L,Liu J,Xu D,Tian G,Jiang T
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Fri Oct 28 00:00:00 EDT 2022
Effects of Hypertonic Saline and Hydroxyethyl Starch on Myeloid-Derived Suppressor Cells in Hemorrhagic Shock Mice under Secondary Bacterial Attack.
BioMed research international
Jiang JK,Hong LJ,Lu YQ
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
Site-1 protease ablation in the osterix-lineage in mice results in bone marrow neutrophilia and hematopoietic stem cell alterations.
Biology open
Patra D,Kim J,Zhang Q,Tycksen E,Sandell LJ
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Tue Jun 23 00:00:00 EDT 2020
The impact of Clonorchis sinensis infection on immune response in mice with type II collagen-induced arthritis.
BMC immunology
Li X,Yang Y,Qin S,Kong F,Yan C,Cheng W,Pan W,Yu Q,Hua H,Zheng K,Tang R
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Mon Feb 17 00:00:00 EST 2020
GDF3 Protects Mice against Sepsis-Induced Cardiac Dysfunction and Mortality by Suppression of Macrophage Pro-Inflammatory Phenotype.
Cells
Wang L,Li Y,Wang X,Wang P,Essandoh K,Cui S,Huang W,Mu X,Liu Z,Wang Y,Peng T,Fan GC
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Fri Jan 03 00:00:00 EST 2020
The Transcription Factor Nfix Requires RhoA-ROCK1 Dependent Phagocytosis to Mediate Macrophage Skewing during Skeletal Muscle Regeneration.
Cells
Saclier M,Lapi M,Bonfanti C,Rossi G,Antonini S,Messina G
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Fri Mar 13 00:00:00 EDT 2020
Extracellular miR-146a-5p Induces Cardiac Innate Immune Response and Cardiomyocyte Dysfunction.
ImmunoHorizons
Shimada BK,Yang Y,Zhu J,Wang S,Suen A,Kronstadt SM,Jeyaram A,Jay SM,Zou L,Chao W
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Mon Sep 21 00:00:00 EDT 2020
Resident macrophages acquire innate immune memory in staphylococcal skin infection.
eLife
Feuerstein R,Forde AJ,Lohrmann F,Kolter J,Ramirez NJ,Zimmermann J,Gomez de Agüero M,Henneke P
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Wed Jul 08 00:00:00 EDT 2020
Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway.
eLife
Kim EH,Woodruff MC,Grigoryan L,Maier B,Lee SH,Mandal P,Cortese M,Natrajan MS,Ravindran R,Ma H,Merad M,Gitlin AD,Mocarski ES,Jacob J,Pulendran B
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Tue Jun 09 00:00:00 EDT 2020
Regulation of the tumor immune microenvironment and vascular normalization in TNBC murine models by a novel peptide.
Oncoimmunology
Mirando AC,Patil A,Rafie CI,Christmas BJ,Pandey NB,Stearns V,Jaffee EM,Roussos Torres ET,Popel AS
48-5932 was used in Flow cytometry/Cell sorting to demonstrate immune-activating properties of AXT201 that could be developed in combination with other immunomodulatory agents in the treatment of TNBC.
Thu May 14 00:00:00 EDT 2020
Dendritic Cells and Microglia Have Non-redundant Functions in the Inflamed Brain with Protective Effects of Type 1 cDCs.
Cell reports
Gallizioli M,Miró-Mur F,Otxoa-de-Amezaga A,Cugota R,Salas-Perdomo A,Justicia C,Brait VH,Ruiz-Jaén F,Arbaizar-Rovirosa M,Pedragosa J,Bonfill-Teixidor E,Gelderblom M,Magnus T,Cano E,Del Fresno C,Sancho D,Planas AM
48-5932 was used in Flow cytometry/Cell sorting to reveal aspects of the dynamics and functions of brain DCs in the regulation of inflammation and immunity.
Tue Oct 20 00:00:00 EDT 2020
Cancer associated fibroblast FAK regulates malignant cell metabolism.
Nature communications
Demircioglu F,Wang J,Candido J,Costa ASH,Casado P,de Luxan Delgado B,Reynolds LE,Gomez-Escudero J,Newport E,Rajeeve V,Baker AM,Roy-Luzarraga M,Graham TA,Foster J,Wang Y,Campbell JJ,Singh R,Zhang P,Schall TJ,Balkwill FR,Sosabowski J,Cutillas PR,Frezza C,Sancho P,Hodivala-Dilke K
48-5932-82 was used in Flow Cytometry to show that cancer-associated fibroblasts regulate malignant cell metabolism through pathways under the control of FAK.
Tue Mar 10 00:00:00 EDT 2020
Gasdermin D in macrophages restrains colitis by controlling cGAS-mediated inflammation.
Science advances
Ma C,Yang D,Wang B,Wu C,Wu Y,Li S,Liu X,Lassen K,Dai L,Yang S
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Host Cathelicidin Exacerbates Group B Streptococcus Urinary Tract Infection.
mSphere
Patras KA,Coady A,Babu P,Shing SR,Ha AD,Rooholfada E,Brandt SL,Geriak M,Gallo RL,Nizet V
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Wed Apr 22 00:00:00 EDT 2020
OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis.
Cell reports
Verboom L,Martens A,Priem D,Hoste E,Sze M,Vikkula H,Van Hove L,Voet S,Roels J,Maelfait J,Bongiovanni L,de Bruin A,Scott CL,Saeys Y,Pasparakis M,Bertrand MJM,van Loo G
48-5932 was used in Flow cytometry/Cell sorting to investigate the effects of ablation of OTILON in liver parenchymal cells on the liver and inflammation using a mouse model.
Tue Feb 18 00:00:00 EST 2020
Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche.
Immunity
Bonnardel J,T'Jonck W,Gaublomme D,Browaeys R,Scott CL,Martens L,Vanneste B,De Prijck S,Nedospasov SA,Kremer A,Van Hamme E,Borghgraef P,Toussaint W,De Bleser P,Mannaerts I,Beschin A,van Grunsven LA,Lambrecht BN,Taghon T,Lippens S,Elewaut D,Saeys Y,Guilliams M
48-5932-82 was used in Flow Cytometry to show that the Kupffer cell niche is composed of stellate cells, hepatocytes, and endothelial cells that together imprint the liver-specific macrophage identity.
Tue Oct 15 00:00:00 EDT 2019
Increased flux through the mevalonate pathway mediates fibrotic repair without injury.
The Journal of clinical investigation
Larson-Casey JL,Vaid M,Gu L,He C,Cai GQ,Ding Q,Davis D,Berryhill TF,Wilson LS,Barnes S,Neighbors JD,Hohl RJ,Zimmerman KA,Yoder BK,Longhini ALF,Hanumanthu VS,Surolia R,Antony VB,Carter AB
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2019
Formyl peptide receptor 2 regulates monocyte recruitment to promote intestinal mucosal wound repair.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Birkl D,O'Leary MN,Quiros M,Azcutia V,Schaller M,Reed M,Nishio H,Keeney J,Neish AS,Lukacs NW,Parkos CA,Nusrat A
48-5932-82 was used in Flow Cytometry to study how Fpr2/3 regulates CCL20-CCR6-mediated monocyte chemotaxis to sites of mucosal injury in the gut to influence wound repair.
Sun Dec 01 00:00:00 EST 2019
Salmonella infection leads to severe intestinal inflammation and increased CD4+FoxP3+ Treg cells in streptozotocin‑induced hyperglycemic mice.
Molecular medicine reports
Zhang S,Wang M,Wang X,Li H,Tang H,Li X
48-5932-82 was used in Flow Cytometry to use streptozotocin‚induced hyperglycemic mice to model T1DM and induced a Salmonella infection in the mouse model, leading to aggravated inflammation, which resulted in an elevated proportion of CD103+CD11b+ DCs and a significantly elevated proportion of CD4+FoxP3+ Tregs in the intestinal lamina propria.
Sat Jun 01 00:00:00 EDT 2019
The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis.
Cell reports
Hou X,Chen G,Bracamonte-Baran W,Choi HS,Diny NL,Sung J,Hughes D,Won T,Wood MK,Talor MV,Hackam DJ,Klingel K,Davogustto G,Taegtmeyer H,Coppens I,Barin JG,Čiháková D
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Tue Jul 02 00:00:00 EDT 2019
Regulatory T Cells Control the Switch From in situ to Invasive Breast Cancer.
Frontiers in immunology
Martinez LM,Robila V,Clark NM,Du W,Idowu MO,Rutkowski MR,Bos PD
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2020
Transcriptional Signature Derived from Murine Tumor-Associated Macrophages Correlates with Poor Outcome in Breast Cancer Patients.
Cell reports
Tuit S,Salvagno C,Kapellos TS,Hau CS,Seep L,Oestreich M,Klee K,de Visser KE,Ulas T,Schultze JL
48-5932 was used in Flow cytometry/Cell sorting to show that a transgenic mouse tumor model can yield a TAM signature relevant for human breast cancer outcome prognosis and provide a generalizable strategy for determining and applying immune cell signatures provided the murine model reflects the human disease.
Tue Oct 29 00:00:00 EDT 2019
Myeloid Cells Restrict MCMV and Drive Stress-Induced Extramedullary Hematopoiesis through STAT1.
Cell reports
Gawish R,Bulat T,Biaggio M,Lassnig C,Bago-Horvath Z,Macho-Maschler S,Poelzl A,Simonović N,Prchal-Murphy M,Rom R,Amenitsch L,Ferrarese L,Kornhoff J,Lederer T,Svinka J,Eferl R,Bosmann M,Kalinke U,Stoiber D,Sexl V,Krmpotić A,Jonjić S,Müller M,Strobl B
48-5932 was used in Flow cytometry/Cell sorting to provide genetic evidence that signaling through STAT1 in myeloid cells is required to restrict MCMV at early time points post-infection and to induce compensatory hematopoiesis in the spleen.
Tue Feb 26 00:00:00 EST 2019
Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner.
Cell
Thion MS,Low D,Silvin A,Chen J,Grisel P,Schulte-Schrepping J,Blecher R,Ulas T,Squarzoni P,Hoeffel G,Coulpier F,Siopi E,David FS,Scholz C,Shihui F,Lum J,Amoyo AA,Larbi A,Poidinger M,Buttgereit A,Lledo PM,Greter M,Chan JKY,Amit I,Beyer M,Schultze JL,Schlitzer A,Pettersson S,Ginhoux F,Garel S
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages.
Immunity
Scott CL,T'Jonck W,Martens L,Todorov H,Sichien D,Soen B,Bonnardel J,De Prijck S,Vandamme N,Cannoodt R,Saelens W,Vanneste B,Toussaint W,De Bleser P,Takahashi N,Vandenabeele P,Henri S,Pridans C,Hume DA,Lambrecht BN,De Baetselier P,Milling SWF,Van Ginderachter JA,Malissen B,Berx G,Beschin A,Saeys Y,Guilliams M
48-5932 was used in Flow cytometry/Cell sorting to demonstrate that ZEB2 expression is required in macrophages to preserve their tissue-specific identities.
Tue Aug 21 00:00:00 EDT 2018
Co-inhibitory Molecule B7 Superfamily Member 1 Expressed by Tumor-Infiltrating Myeloid Cells Induces Dysfunction of Anti-tumor CD8+ T Cells.
Immunity
Li J,Lee Y,Li Y,Jiang Y,Lu H,Zang W,Zhao X,Liu L,Chen Y,Tan H,Yang Z,Zhang MQ,Mak TW,Ni L,Dong C
48-5932 was used in Flow cytometry/Cell sorting to demonstrate that increased B7S1 expression in myeloid cells from human hepatocellular carcinoma is correlated with CD8+ T cell dysfunction.
Tue Apr 17 00:00:00 EDT 2018
Ferritin H Deficiency in Myeloid Compartments Dysregulates Host Energy Metabolism and Increases Susceptibility to Mycobacterium tuberculosis Infection.
Frontiers in immunology
Reddy VP,Chinta KC,Saini V,Glasgow JN,Hull TD,Traylor A,Rey-Stolle F,Soares MP,Madansein R,Rahman MA,Barbas C,Nargan K,Naidoo T,Ramdial PK,George JF,Agarwal A,Steyn AJC
48-5932 was used in Flow cytometry/Cell sorting to examine the impact of a lack of ferritin heavy chain in exacerbating susceptibility to Mycobacterium tuberculosis infection, through the disruption of iron homeostasis.
Mon Jul 22 00:00:00 EDT 2019
Murine CMV induces type 1 IFN that impairs differentiation of MDSCs critical for transplantation tolerance.
Blood advances
Dangi A,Zhang L,Zhang X,Luo X
48-5932 was used in Flow cytometry/Cell sorting to provide a solid foundation for seeking effective therapies for promoting transplantation tolerance in settings of CMV infection.
Tue Mar 27 00:00:00 EDT 2018
Advanced Glycation End Products Enhance Murine Monocyte Proliferation in Bone Marrow and Prime Them into an Inflammatory Phenotype through MAPK Signaling.
Journal of diabetes research
Jin X,Liu L,Zhang Y,Xiang Y,Yin G,Lu Y,Shi L,Dong J,Shen C
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Wed Oct 10 00:00:00 EDT 2018
iRhom2-mediated proinflammatory signalling regulates heart repair following myocardial infarction.
JCI insight
Barnette DN,Cahill TJ,Gunadasa-Rohling M,Carr CA,Freeman M,Riley PR
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Thu Feb 08 00:00:00 EST 2018
Differentiated macrophages acquire a pro-inflammatory and cell death-resistant phenotype due to increasing XIAP and p38-mediated inhibition of RipK1.
The Journal of biological chemistry
Rijal D,Ariana A,Wight A,Kim K,Alturki NA,Aamir Z,Ametepe ES,Korneluk RG,Tiedje C,Menon MB,Gaestel M,McComb S,Sad S
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Fri Jul 27 00:00:00 EDT 2018
The Combined Use of Melatonin and an Indoleamine 2,3-Dioxygenase-1 Inhibitor Enhances Vaccine-Induced Protective Cellular Immunity to HPV16-Associated Tumors.
Frontiers in immunology
Moreno ACR,Porchia BFMM,Pagni RL,Souza PDC,Pegoraro R,Rodrigues KB,Barros TB,Aps LRMM,de Araújo EF,Calich VLG,Ferreira LCS
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Thu Sep 19 00:00:00 EDT 2019
Bcl11b is essential for licensing Th2 differentiation during helminth infection and allergic asthma.
Nature communications
Lorentsen KJ,Cho JJ,Luo X,Zuniga AN,Urban JF,Zhou L,Gharaibeh R,Jobin C,Kladde MP,Avram D
48-5932 was used in Flow cytometry/Cell sorting to establish novel roles for Bcl11b in the regulatory loop that licenses Th2 program in vivo.
Thu Apr 26 00:00:00 EDT 2018
Dipeptidyl Peptidase-4 Is a Pro-Recovery Mediator During Acute Hepatotoxic Damage and Mirrors Severe Shifts in Kupffer Cells.
Hepatology communications
Duarte N,Coelho I,Holovanchuk D,Inês Almeida J,Penha-Gonçalves C,Paula Macedo M
48-5932 was used in Flow cytometry/Cell sorting to study the involvement of dipeptidyl peptidase-4 in acute liver damage, and reveal its pro-recovery properties.
Sat Sep 01 00:00:00 EDT 2018
Eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challenge.
Nature communications
Yi S,Zhai J,Niu R,Zhu G,Wang M,Liu J,Huang H,Wang Y,Jing X,Kang L,Song W,Shi Y,Tang H
48-5932 was used in Flow cytometry/Cell sorting to suggest that different lung antigen-presenting cells modulate lung cDC1-mediated eosinophil recruitment dynamically.
Mon Sep 24 00:00:00 EDT 2018
Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling.
The Journal of clinical investigation
Quiros M,Nishio H,Neumann PA,Siuda D,Brazil JC,Azcutia V,Hilgarth R,O'Leary MN,Garcia-Hernandez V,Leoni G,Feng M,Bernal G,Williams H,Dedhia PH,Gerner-Smidt C,Spence J,Parkos CA,Denning TL,Nusrat A
48-5932 was used in Flow cytometry/Cell sorting to investigate the mechanisms involved in crosstalk between immune cells and the epithelium in mucosal barrier repair.
Fri Sep 01 00:00:00 EDT 2017
Mir-223 regulates the number and function of myeloid-derived suppressor cells in multiple sclerosis and experimental autoimmune encephalomyelitis.
Acta neuropathologica
Cantoni C,Cignarella F,Ghezzi L,Mikesell B,Bollman B,Berrien-Elliott MM,Ireland AR,Fehniger TA,Wu GF,Piccio L
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
CCR2- and CCR2+ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion.
Mucosal immunology
Liu J,Xue Y,Dong D,Xiao C,Lin C,Wang H,Song F,Fu T,Wang Z,Chen J,Pan H,Li Y,Cai D,Li Z
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2017
Infiltrating Myeloid Cells Exert Protumorigenic Actions via Neutrophil Elastase.
Molecular cancer research : MCR
Lerman I,Garcia-Hernandez ML,Rangel-Moreno J,Chiriboga L,Pan C,Nastiuk KL,Krolewski JJ,Sen A,Hammes SR
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2017
Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression.
Nature communications
Kalkavan H,Sharma P,Kasper S,Helfrich I,Pandyra AA,Gassa A,Virchow I,Flatz L,Brandenburg T,Namineni S,Heikenwalder M,Höchst B,Knolle PA,Wollmann G,von Laer D,Drexler I,Rathbun J,Cannon PM,Scheu S,Bauer J,Chauhan J,Häussinger D,Willimsky G,Löhning M,Schadendorf D,Brandau S,Schuler M,Lang PA,Lang KS
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages.
Oncoimmunology
Kersten K,Coffelt SB,Hoogstraat M,Verstegen NJM,Vrijland K,Ciampricotti M,Doornebal CW,Hau CS,Wellenstein MD,Salvagno C,Doshi P,Lips EH,Wessels LFA,de Visser KE
48-5932 was used in Flow cytometry/Cell sorting to demonstrate mammary tumor-derived CCL2 can facilitate the breast cancer-induced pro-metastatic systemic inflammatory gamma delta T cell-IL17–neutrophil axis.
Sat Jan 29 00:00:00 EST 2022
Isolation and Identification of Intestinal Myeloid Cells.
Methods in molecular biology (Clifton, N.J.)
Scott CL,Bain CC,Mowat AM
48593282 was used in flow cytometry to identify myeloid cells obtained from mouse intestine.
Wed Jan 31 00:00:00 EST 2018
Toxoplasma Co-infection Prevents Th2 Differentiation and Leads to a Helminth-Specific Th1 Response.
Frontiers in cellular and infection microbiology
Ahmed N,French T,Rausch S,Kühl A,Hemminger K,Dunay IR,Steinfelder S,Hartmann S
48-5932 was used in Flow cytometry/Cell sorting to conclude a previous T. gondii infection limits a helminth-specific Th2 immune response while promoting a shift toward a Th1-type immune response.
Mon Apr 02 00:00:00 EDT 2018
IL-17C is required for lethal inflammation during systemic fungal infection.
Cellular & molecular immunology
Huang J,Meng S,Hong S,Lin X,Jin W,Dong C
48-5932 was used in Flow cytometry/Cell sorting to elucidate the function of the IL-17 family members in anti-fungal immunity.
Fri Jul 01 00:00:00 EDT 2016
Alternatively activated macrophages determine repair of the infarcted adult murine heart.
The Journal of clinical investigation
Shiraishi M,Shintani Y,Shintani Y,Ishida H,Saba R,Yamaguchi A,Adachi H,Yashiro K,Suzuki K
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.
Science translational medicine
Dendrou CA,Cortes A,Shipman L,Evans HG,Attfield KE,Jostins L,Barber T,Kaur G,Kuttikkatte SB,Leach OA,Desel C,Faergeman SL,Cheeseman J,Neville MJ,Sawcer S,Compston A,Johnson AR,Everett C,Bell JI,Karpe F,Ultsch M,Eigenbrot C,McVean G,Fugger L
48-5932 was used in Flow cytometry/Cell sorting to reveal a protective homozygous effect that defined a signalling optimum between autoimmunity and immunodeficiency and identified TYK2 as a potential drug target for autoimmune disorders.
Wed Nov 02 00:00:00 EDT 2016
Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.
Immunology
Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H
48-5932 was used in Flow cytometry/Cell sorting to identify a novel pathway of cross-talk between macrophages and dendritic cells.
Sat Oct 01 00:00:00 EDT 2016
Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model.
Disease models & mechanisms
Chu CJ,Gardner PJ,Copland DA,Liyanage SE,Gonzalez-Cordero A,Kleine Holthaus SM,Luhmann UF,Smith AJ,Ali RR,Dick AD
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2016
MIF Promotes Classical Activation and Conversion of Inflammatory Ly6C(high) Monocytes into TipDCs during Murine Toxoplasmosis.
Mediators of inflammation
Ruiz-Rosado Jde D,Olguín JE,Juárez-Avelar I,Saavedra R,Terrazas LI,Robledo-Avila FH,Vazquez-Mendoza A,Fernández J,Satoskar AR,Partida-Sánchez S,Rodriguez-Sosa M
48-5932 was used in Flow cytometry/Cell sorting to analyse the role of migration inhibitory factor in the maturation of CD11b(+) and CD8α (+) dendritic cells.
Fri Dec 30 00:00:00 EST 2016
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
Nature communications
Ruhland MK,Loza AJ,Capietto AH,Luo X,Knolhoff BL,Flanagan KC,Belt BA,Alspach E,Leahy K,Luo J,Schaffer A,Edwards JR,Longmore G,Faccio R,DeNardo DG,Stewart SA
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Wed Jun 08 00:00:00 EDT 2016
Ranitidine modifies myeloid cell populations and inhibits breast tumor development and spread in mice.
Oncoimmunology
Vila-Leahey A,Oldford SA,Marignani PA,Wang J,Haidl ID,Marshall JS
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Fri Jul 01 00:00:00 EDT 2016
The impact of ranitidine on monocyte responses in the context of solid tumors.
Oncotarget
Vila-Leahey A,Rogers D,Marshall JS
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Tue Mar 08 00:00:00 EST 2016
Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.
Scientific reports
Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Wed Jun 15 00:00:00 EDT 2016
Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells.
Aging
Hall BM,Balan V,Gleiberman AS,Strom E,Krasnov P,Virtuoso LP,Rydkina E,Vujcic S,Balan K,Gitlin I,Leonova K,Polinsky A,Chernova OB,Gudkov AV
48-5932 was used in Flow cytometry/Cell sorting to investigate the role of p16(Ink4a)/β-gal(pH6)-positive macrophages in aging, which previously was attributed solely to senescent cells.
Fri Jul 01 00:00:00 EDT 2016
Macrophage and epithelial cell H-ferritin expression regulates renal inflammation.
Kidney international
Bolisetty S,Zarjou A,Hull TD,Traylor AM,Perianayagam A,Joseph R,Kamal AI,Arosio P,Soares MP,Jeney V,Balla J,George JF,Agarwal A
48-5932 was used in Flow cytometry/Cell sorting to explore the critical role of the heavy subunit of ferritin in tubular-macrophage cross-talk during kidney injury.
Wed Jul 01 00:00:00 EDT 2015
Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection.
PLoS pathogens
Wiesner DL,Specht CA,Lee CK,Smith KD,Mukaremera L,Lee ST,Lee CG,Elias JA,Nielsen JN,Boulware DR,Bohjanen PR,Jenkins MK,Levitz SM,Nielsen K
48-5932 was used in Flow cytometry/Cell sorting to investigate Th2 cell responses to pulmonary fungal infection, showing that chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection.
Sun Mar 01 00:00:00 EST 2015
A novel Cd8-cis-regulatory element preferentially directs expression in CD44hiCD62L+ CD8+ T cells and in CD8αα+ dendritic cells.
Journal of leukocyte biology
Sakaguchi S,Hombauer M,Hassan H,Tanaka H,Yasmin N,Naoe Y,Bilic I,Moser MA,Hainberger D,Mayer H,Seiser C,Bergthaler A,Taniuchi I,Ellmeier W
48-5932 was used in Flow cytometry/Cell sorting to identify a novel Cd8 enhancer that directs expression in CD44(hi)CD62L(+) CD8(+) T cells, including innate-like and antigen-specific effector/memory CD8(+) T cells and in CD8αα(+) DCs.
Wed Apr 01 00:00:00 EDT 2015
Diverse roles for T-bet in the effector responses required for resistance to infection.
Journal of immunology (Baltimore, Md. : 1950)
Harms Pritchard G,Hall AO,Christian DA,Wagage S,Fang Q,Muallem G,John B,Glatman Zaretsky A,Dunn WG,Perrigoue J,Reiner SL,Hunter CA
48-5932 was used in Flow cytometry/Cell sorting to highlight T-bet-independent pathways to IFN-γ production and reveal a novel role for this transcription factor in coordinating the T cell responses necessary to control infection in peripheral tissues.
Sun Feb 01 00:00:00 EST 2015
Cysteine cathepsin activity suppresses osteoclastogenesis of myeloid-derived suppressor cells in breast cancer.
Oncotarget
Edgington-Mitchell LE,Rautela J,Duivenvoorden HM,Jayatilleke KM,van der Linden WA,Verdoes M,Bogyo M,Parker BS
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2015
Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.
PloS one
Szulzewsky F,Pelz A,Feng X,Synowitz M,Markovic D,Langmann T,Holtman IR,Wang X,Eggen BJ,Boddeke HW,Hambardzumyan D,Wolf SA,Kettenmann H
Published figure using Ly-6C monoclonal antibody (Product # 48-5932-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2016
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
Nature immunology
Franklin BS,Bossaller L,De Nardo D,Ratter JM,Stutz A,Engels G,Brenker C,Nordhoff M,Mirandola SR,Al-Amoudi A,Mangan MS,Zimmer S,Monks BG,Fricke M,Schmidt RE,Espevik T,Jones B,Jarnicki AG,Hansbro PM,Busto P,Marshak-Rothstein A,Hornemann S,Aguzzi A,Kastenmüller W,Latz E
48-5932 was used in Flow cytometry/Cell sorting to study the behaviour of ASC specks and their contribution to IL-1β - induced inflammation.
Fri Aug 01 00:00:00 EDT 2014
Leucocyte expression of complement C5a receptors exacerbates infarct size after myocardial reperfusion injury.
Cardiovascular research
De Hoog VC,Timmers L,Van Duijvenvoorde A,De Jager SC,Van Middelaar BJ,Smeets MB,Woodruff TM,Doevendans PA,Pasterkamp G,Hack CE,De Kleijn DP
48-5932 was used in Flow cytometry/Cell sorting to demonstrate that selective blocking of C5aR might be a promising strategy to prevent myocardial ischaemia-reperfusion injury.
Mon Sep 01 00:00:00 EDT 2014
Preemptive donor apoptotic cell infusions induce IFN-γ-producing myeloid-derived suppressor cells for cardiac allograft protection.
Journal of immunology (Baltimore, Md. : 1950)
Bryant J,Lerret NM,Wang JJ,Kang HK,Tasch J,Zhang Z,Luo X
48-5932 was used in Flow cytometry/Cell sorting to investigate the role of MDSCs in the graft protection provided by ECDI-SPs, showing that preemptive donor apoptotic cell infusions induce IFN-γ-producing MDSCs.
Sun Jun 15 00:00:00 EDT 2014
