Product References
Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota.
Cell
Lima-Junior DS,Krishnamurthy SR,Bouladoux N,Collins N,Han SJ,Chen EY,Constantinides MG,Link VM,Lim AI,Enamorado M,Cataisson C,Gil L,Rao I,Farley TK,Koroleva G,Attig J,Yuspa SH,Fischbach MA,Kassiotis G,Belkaid Y
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Thu Jul 08 00:00:00 EDT 2021
Regionally diverse astrocyte subtypes and their heterogeneous response to EAE.
Glia
Borggrewe M,Grit C,Vainchtein ID,Brouwer N,Wesseling EM,Laman JD,Eggen BJL,Kooistra SM,Boddeke EWGM
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunohistochemistry
Sat May 01 00:00:00 EDT 2021
CD11b Deficiency Exacerbates Methicillin-Resistant Staphylococcus aureus-Induced Sepsis by Upregulating Inflammatory Responses of Macrophages.
Immune network
Sim H,Jeong D,Kim HI,Pak S,Thapa B,Kwon HJ,Lee K
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Prostaglandin E2 serves a dual role in regulating the migration of dendritic cells.
International journal of molecular medicine
Diao G,Huang J,Zheng X,Sun X,Tian M,Han J,Guo J
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Wip1 regulates the immunomodulatory effects of murine mesenchymal stem cells in type 1 diabetes mellitus via targeting IFN-α/BST2.
Cell death discovery
Zhou N,Liu W,Zhang W,Liu Y,Li X,Wang Y,Zheng R,Zhang Y
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Fri Oct 29 00:00:00 EDT 2021
Topical arginase inhibition decreases growth of cutaneous squamous cell carcinoma.
Scientific reports
Mittal A,Wang M,Vidyarthi A,Yanez D,Pizzurro G,Thakral D,Tracy E,Colegio OR
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Mon May 24 00:00:00 EDT 2021
Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma.
Cell reports
Budhu S,Giese R,Gupta A,Fitzgerald K,Zappasodi R,Schad S,Hirschhorn D,Campesato LF,De Henau O,Gigoux M,Liu C,Mazo G,Deng L,Barker CA,Wolchok JD,Merghoub T
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Transgene distribution and immune response after ultrasound delivery of rAAV9 and PHP.B to the brain in a mouse model of amyloidosis.
Molecular therapy. Methods & clinical development
Kofoed RH,Heinen S,Silburt J,Dubey S,Dibia CL,Maes M,Simpson EM,Hynynen K,Aubert I
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunocytochemistry
Fri Dec 10 00:00:00 EST 2021
Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway.
Journal of neuroinflammation
Duan RN,Yang CL,Du T,Liu A,Wang AR,Sun WJ,Li X,Li JX,Yan CZ,Liu QJ
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Mon Jun 28 00:00:00 EDT 2021
Frequent amplification of HDAC genes and efficacy of HDAC inhibitor chidamide and PD-1 blockade combination in soft tissue sarcoma.
Journal for immunotherapy of cancer
Que Y,Zhang XL,Liu ZX,Zhao JJ,Pan QZ,Wen XZ,Xiao W,Xu BS,Hong DC,Guo TH,Shen LJ,Fan WJ,Chen HY,Weng DS,Xu HR,Zhou PH,Zhang YZ,Niu XH,Zhang X
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Early activation of the cardiac CX3CL1/CX3CR1 axis delays β-adrenergic-induced heart failure.
Scientific reports
Flamant M,Mougenot N,Balse E,Le Fèvre L,Atassi F,Gautier EL,Le Goff W,Keck M,Nadaud S,Combadière C,Boissonnas A,Pavoine C
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Thu Sep 09 00:00:00 EDT 2021
PP2Cδ Controls the Differentiation and Function of Dendritic Cells Through Regulating the NSD2/mTORC2/ACLY Pathway.
Frontiers in immunology
Lv N,Jin S,Liang Z,Wu X,Kang Y,Su L,Dong Y,Wang B,Ma T,Shi L
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Mon Feb 28 00:00:00 EST 2022
Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment.
Cell
Lam KC,Araya RE,Huang A,Chen Q,Di Modica M,Rodrigues RR,Lopès A,Johnson SB,Schwarz B,Bohrnsen E,Cogdill AP,Bosio CM,Wargo JA,Lee MP,Goldszmid RS
13-5321-82 was used in Flow cytometry/Cell sorting to uncover a mechanistic link between the microbiota and the innate TME that can be harnessed to improve cancer therapies.
Thu Oct 14 00:00:00 EDT 2021
Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis.
Frontiers in immunology
Yang P,Tian H,Zou YR,Chambon P,Ichinose H,Honig G,Diamond B,Kim SJ
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
The subunits of IL-12, originating from two distinct cells, can functionally synergize to protect against pathogen dissemination in vivo.
Cell reports
Gerber AN,Abdi K,Singh NJ
13-5321-82 was used in Flow cytometry/Cell sorting to suggest that early secretion of IL-12p40 monomers by sentinel cells at the infection site may help prepare distal host tissues for potential pathogen arrival.
Tue Oct 12 00:00:00 EDT 2021
ARPC1B binds WASP to control actin polymerization and curtail tonic signaling in B cells.
JCI insight
Leung G,Zhou Y,Ostrowski P,Mylvaganam S,Boroumand P,Mulder DJ,Guo C,Muise AM,Freeman SA
13-5321-82 was used in Immunocytochemistry to conclude that ARPC1B is critical for ARP2/3 complexes to control steady-state signaling of immune cells.
Wed Dec 08 00:00:00 EST 2021
Systemic Inflammation Accelerates Changes in Microglial and Synaptic Markers in an Experimental Model of Chronic Neurodegeneration.
Frontiers in neuroscience
Chouhan JK,Püntener U,Booth SG,Teeling JL
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunohistochemistry
Sat Jan 22 00:00:00 EST 2022
Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy.
Immunity
Milner JJ,Toma C,He Z,Kurd NS,Nguyen QP,McDonald B,Quezada L,Widjaja CE,Witherden DA,Crowl JT,Shaw LA,Yeo GW,Chang JT,Omilusik KD,Goldrath AW
13-5321 was used in Flow cytometry/Cell sorting to identify discrete lineages of intestinal antigen-specific CD8+ T cells, including a Blimp1hiId3lo tissue-resident effector cell population most prominent in the early phase of acute viral and bacterial infections and a molecularly distinct Blimp1loId3hi tissue-resident memory population that subsequently accumulated at later infection time points.
Tue May 19 00:00:00 EDT 2020
Glufosinate constrains synchronous and metachronous metastasis by promoting anti-tumor macrophages.
EMBO molecular medicine
Menga A,Serra M,Todisco S,Riera-Domingo C,Ammarah U,Ehling M,Palmieri EM,Di Noia MA,Gissi R,Favia M,Pierri CL,Porporato PE,Castegna A,Mazzone M
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Wed Oct 07 00:00:00 EDT 2020
Exosomes derived from microglia exposed to elevated pressure amplify the neuroinflammatory response in retinal cells.
Glia
Aires ID,Ribeiro-Rodrigues T,Boia R,Catarino S,Girão H,Ambrósio AF,Santiago AR
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunocytochemistry
Tue Dec 01 00:00:00 EST 2020
NLRX1 is a key regulator of immune signaling during invasive pulmonary aspergillosis.
PLoS pathogens
Kastelberg B,Tubau-Juni N,Ayubi T,Leung A,Leber A,Hontecillas R,Bassaganya-Riera J,Kale SD
13-5321 was used in Flow cytometry/Cell sorting to point strongly towards the cell-specific and contextual function of Nlrx1 during invasive pulmonary aspergillosis and may lead to novel therapeutics to reduce Th2 responses by CD103+ DCs or heightened recruitment of neutrophils.
Tue Sep 01 00:00:00 EDT 2020
E6‑regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16‑positive cervical lesions.
International journal of oncology
Huang J,Diao G,Zhang Q,Chen Y,Han J,Guo J
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
IFN-β signalling regulates RAW 264.7 macrophage activation, cytokine production, and killing activity.
Innate immunity
Karimi Y,Giles EC,Vahedi F,Chew MV,Nham T,Loukov D,Lee AJ,Bowdish DM,Ashkar AA
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Dietary Glucose Consumption Promotes RALDH Activity in Small Intestinal CD103+CD11b+ Dendritic Cells.
Frontiers in immunology
Ko HJ,Hong SW,Verma R,Jung J,Lee M,Kim N,Kim D,Surh CD,Kim KS,Rudra D,Im SH
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Mon Apr 19 00:00:00 EDT 2021
GDF3 Protects Mice against Sepsis-Induced Cardiac Dysfunction and Mortality by Suppression of Macrophage Pro-Inflammatory Phenotype.
Cells
Wang L,Li Y,Wang X,Wang P,Essandoh K,Cui S,Huang W,Mu X,Liu Z,Wang Y,Peng T,Fan GC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Fri Jan 03 00:00:00 EST 2020
Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells.
Nature communications
Lucas B,White AJ,Cosway EJ,Parnell SM,James KD,Jones ND,Ohigashi I,Takahama Y,Jenkinson WE,Anderson G
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Mon May 04 00:00:00 EDT 2020
Smooth muscle-derived progenitor cell myofibroblast differentiation through KLF4 downregulation promotes arterial remodeling and fibrosis.
JCI insight
Lu S,Jolly AJ,Strand KA,Dubner AM,Mutryn MF,Moulton KS,Nemenoff RA,Majesky MW,Weiser-Evans MC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Thu Dec 03 00:00:00 EST 2020
Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection.
Cell reports
Dokoshi T,Zhang LJ,Li F,Nakatsuji T,Butcher A,Yoshida H,Shimoda M,Okada Y,Gallo RL
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Tue Jan 07 00:00:00 EST 2020
Ly6cLo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation.
Scientific reports
Alkhani A,Levy CS,Tsui M,Rosenberg KA,Polovina K,Mattis AN,Mack M,Van Dyken S,Wang BM,Maher JJ,Nijagal A
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Tue Apr 28 00:00:00 EDT 2020
MiR-103 protects from recurrent spontaneous abortion via inhibiting STAT1 mediated M1 macrophage polarization.
International journal of biological sciences
Zhu X,Liu H,Zhang Z,Wei R,Zhou X,Wang Z,Zhao L,Guo Q,Zhang Y,Chu C,Wang L,Li X
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Fri Nov 12 00:00:00 EST 2021
Cancer cell-intrinsic expression of MHC II in lung cancer cell lines is actively restricted by MEK/ERK signaling and epigenetic mechanisms.
Journal for immunotherapy of cancer
Neuwelt AJ,Kimball AK,Johnson AM,Arnold BW,Bullock BL,Kaspar RE,Kleczko EK,Kwak JW,Wu MH,Heasley LE,Doebele RC,Li HY,Nemenoff RA,Clambey ET
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Immunomodulatory Effects of Recombinant Mycobacterium smegmatis Expressing Antigen-85B Epitopes in Infected J774A.1 Murine Macrophages.
Pathogens (Basel, Switzerland)
Kadir NA,Acosta A,Sarmiento ME,Norazmi MN
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Sun Nov 29 00:00:00 EST 2020
Artificial Mini Dendritic Cells Boost T Cell-Based Immunotherapy for Ovarian Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Cheng S,Xu C,Jin Y,Li Y,Zhong C,Ma J,Yang J,Zhang N,Li Y,Wang C,Yang Z,Wang Y
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Optimized Protocol for Isolation of Small Extracellular Vesicles from Human and Murine Lymphoid Tissues.
International journal of molecular sciences
Bordas M,Genard G,Ohl S,Nessling M,Richter K,Roider T,Dietrich S,Maaß KK,Seiffert M
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Tue Aug 04 00:00:00 EDT 2020
Skeletal muscle healing by M1-like macrophages produced by transient expression of exogenous GM-CSF.
Stem cell research & therapy
Martins L,Gallo CC,Honda TSB,Alves PT,Stilhano RS,Rosa DS,Koh TJ,Han SW
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Fri Nov 06 00:00:00 EST 2020
Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine.
Nature communications
Campesato LF,Budhu S,Tchaicha J,Weng CH,Gigoux M,Cohen IJ,Redmond D,Mangarin L,Pourpe S,Liu C,Zappasodi R,Zamarin D,Cavanaugh J,Castro AC,Manfredi MG,McGovern K,Merghoub T,Wolchok JD
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Tue Aug 11 00:00:00 EDT 2020
Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses.
Scientific reports
Hrdý J,Alard J,Couturier-Maillard A,Boulard O,Boutillier D,Delacre M,Lapadatescu C,Cesaro A,Blanc P,Pot B,Ryffel B,Chamaillard M,Grangette C
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Tue Mar 24 00:00:00 EDT 2020
Nuclear imaging-guided PD-L1 blockade therapy increases effectiveness of cancer immunotherapy.
Journal for immunotherapy of cancer
Gao H,Wu Y,Shi J,Zhang X,Liu T,Hu B,Jia B,Wan Y,Liu Z,Wang F
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Fri Jun 19 00:00:00 EDT 2020
RON Expression Mediates Lipopolysaccharide-Mediated Dendritic Cell Maturation via March-I.
Frontiers in cellular and infection microbiology
Huang L,Fang X,Zhang X,Wu W,Yao H,Fang Q
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunoprecipitation
Sun Apr 02 00:00:00 EDT 2023
CDK4/6 inhibition promotes immune infiltration in ovarian cancer and synergizes with PD-1 blockade in a B cell-dependent manner.
Theranostics
Zhang QF,Li J,Jiang K,Wang R,Ge JL,Yang H,Liu SJ,Jia LT,Wang L,Chen BL
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Tue Jun 01 00:00:00 EDT 2021
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Mon Jun 29 00:00:00 EDT 2020
Polyanhydride Nanoparticles Induce Low Inflammatory Dendritic Cell Activation Resulting in CD8+ T Cell Memory and Delayed Tumor Progression.
International journal of nanomedicine
Darling R,Senapati S,Christiansen J,Liu L,Ramer-Tait AE,Narasimhan B,Wannemuehler M
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Mon Dec 07 00:00:00 EST 2020
cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity.
The Journal of clinical investigation
Wang Z,Chen J,Hu J,Zhang H,Xu F,He W,Wang X,Li M,Lu W,Zeng G,Zhou P,Huang P,Chen S,Li W,Xia LP,Xia X
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Tue Aug 13 00:00:00 EDT 2019
Critical Adverse Impact of IL-6 in Acute Pneumovirus Infection.
Journal of immunology (Baltimore, Md. : 1950)
Percopo CM,Ma M,Brenner TA,Krumholz JO,Break TJ,Laky K,Rosenberg HF
13-5321 was used in Flow cytometry/Cell sorting to examine the role of the pleiotropic cytokine IL-6 in acute infection with pneumonia virus of mice.
Fri Feb 01 00:00:00 EST 2019
Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection-Induced Neuropathic Pain.
Pain research & management
Sheng WS,Chauhan P,Hu S,Prasad S,Lokensgard JR
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Mon Dec 16 00:00:00 EST 2019
Intravitreal injection of adenosine A2A receptor antagonist reduces neuroinflammation, vascular leakage and cell death in the retina of diabetic mice.
Scientific reports
Aires ID,Madeira MH,Boia R,Rodrigues-Neves AC,Martins JM,Ambrósio AF,Santiago AR
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunohistochemistry
Wed Nov 20 00:00:00 EST 2019
MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.
Journal for immunotherapy of cancer
Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Thu Nov 28 00:00:00 EST 2019
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
Macrophage-specific MHCII expression is regulated by a remote Ciita enhancer controlled by NFAT5.
The Journal of experimental medicine
Buxadé M,Huerga Encabo H,Riera-Borrull M,Quintana-Gallardo L,López-Cotarelo P,Tellechea M,Martínez-Martínez S,Redondo JM,Martín-Caballero J,Flores JM,Bosch E,Rodríguez-Fernández JL,Aramburu J,López-Rodríguez C
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Mon Nov 05 00:00:00 EST 2018
Functional antagonism of sphingosine-1-phosphate receptor 1 prevents cuprizone-induced demyelination.
Glia
Kim S,Bielawski J,Yang H,Kong Y,Zhou B,Li J
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunocytochemistry
Thu Mar 01 00:00:00 EST 2018
Functional antagonism of sphingosine-1-phosphate receptor 1 prevents cuprizone-induced demyelination.
Glia
Kim S,Bielawski J,Yang H,Kong Y,Zhou B,Li J
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunocytochemistry
Thu Mar 01 00:00:00 EST 2018
Age Influences Microglial Activation After Cuprizone-Induced Demyelination.
Frontiers in aging neuroscience
Klein B,Mrowetz H,Barker CM,Lange S,Rivera FJ,Aigner L
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunofluorescence
Thu Oct 01 00:00:00 EDT 2020
FACS isolation of live mouse eosinophils at high purity via a protocol that does not target Siglec F.
Journal of immunological methods
Geslewitz WE,Percopo CM,Rosenberg HF
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2018
Myeloid apolipoprotein E controls dendritic cell antigen presentation and T cell activation.
Nature communications
Bonacina F,Coe D,Wang G,Longhi MP,Baragetti A,Moregola A,Garlaschelli K,Uboldi P,Pellegatta F,Grigore L,Da Dalt L,Annoni A,Gregori S,Xiao Q,Caruso D,Mitro N,Catapano AL,Marelli-Berg FM,Norata GD
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Mon Aug 06 00:00:00 EDT 2018
CD4+ T cells are activated in regional lymph nodes and migrate to skin to initiate lymphedema.
Nature communications
García Nores GD,Ly CL,Cuzzone DA,Kataru RP,Hespe GE,Torrisi JS,Huang JJ,Gardenier JC,Savetsky IL,Nitti MD,Yu JZ,Rehal S,Mehrara BJ
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Thu May 17 00:00:00 EDT 2018
Lin-CCR2+ hematopoietic stem and progenitor cells overcome resistance to PD-1 blockade.
Nature communications
Flores CT,Wildes TJ,Drake JA,Moore GL,Dean BD,Abraham RS,Mitchell DA
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Wed Oct 17 00:00:00 EDT 2018
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
The Journal of clinical investigation
Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells.
Frontiers in immunology
Bai WJ,Li CG,Zhang CC,Xu LH,Zeng QZ,Hu B,Hong Z,He XH,Ouyang DY
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice.
Neurobiology of disease
MacPherson KP,Sompol P,Kannarkat GT,Chang J,Sniffen L,Wildner ME,Norris CM,Tansey MG
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
Cooperation of Gastric Mononuclear Phagocytes with Helicobacter pylori during Colonization.
Journal of immunology (Baltimore, Md. : 1950)
Viladomiu M,Bassaganya-Riera J,Tubau-Juni N,Kronsteiner B,Leber A,Philipson CW,Zoccoli-Rodriguez V,Hontecillas R
13-5321 was used in Flow cytometry/Cell sorting to report the induction of IL-10-driven regulatory responses mediated by CD11b+F4/80hiCD64+CX3CR1+ MNPs that contribute to maintaining high levels of Helicobacter pylori loads in the stomach by modulating effector T cell responses at the gastric mucosa.
Sat Apr 15 00:00:00 EDT 2017
Discrimination of the heterogeneity of bone marrow‑derived dendritic cells.
Molecular medicine reports
Wang J,Dai X,Hsu C,Ming C,He Y,Zhang J,Wei L,Zhou P,Wang CY,Yang J,Gong N
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Wed Nov 01 00:00:00 EDT 2017
Loss of IRF2BP2 in Microglia Increases Inflammation and Functional Deficits after Focal Ischemic Brain Injury.
Frontiers in cellular neuroscience
Cruz SA,Hari A,Qin Z,Couture P,Huang H,Lagace DC,Stewart AFR,Chen HH
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Thu Mar 17 00:00:00 EDT 2022
Role of a novel immune modulating DDR2-expressing population in silica-induced pulmonary fibrosis.
PloS one
McDonald LT,Johnson SD,Russell DL,Young MRI,LaRue AC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Mon Sep 25 00:00:00 EDT 2017
Heavy Chain-Hyaluronan/Pentraxin 3 from Amniotic Membrane Suppresses Inflammation and Scarring in Murine Lacrimal Gland and Conjunctiva of Chronic Graft-versus-Host Disease.
Scientific reports
Ogawa Y,He H,Mukai S,Imada T,Nakamura S,Su CW,Mahabole M,Tseng SC,Tsubota K
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunofluorescence
Mon Feb 06 00:00:00 EST 2017
Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy.
JCI insight
Yanagita T,Murata Y,Tanaka D,Motegi SI,Arai E,Daniwijaya EW,Hazama D,Washio K,Saito Y,Kotani T,Ohnishi H,Oldenborg PA,Garcia NV,Miyasaka M,Ishikawa O,Kanai Y,Komori T,Matozaki T
13-5321 was used in Flow cytometry/Cell sorting to show that SIRPα is highly expressed in human renal cell carcinoma and melanoma, and that anti-SIRPα antibody blocks the interaction with CD47, suppressing tumor formation by renal cell carcinoma or melanoma cells.
Thu Jan 12 00:00:00 EST 2017
Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy.
JCI insight
Yanagita T,Murata Y,Tanaka D,Motegi SI,Arai E,Daniwijaya EW,Hazama D,Washio K,Saito Y,Kotani T,Ohnishi H,Oldenborg PA,Garcia NV,Miyasaka M,Ishikawa O,Kanai Y,Komori T,Matozaki T
13-5321 was used in Flow cytometry/Cell sorting to show that SIRPα is highly expressed in human renal cell carcinoma and melanoma, and that anti-SIRPα antibody blocks the interaction with CD47, suppressing tumor formation by renal cell carcinoma or melanoma cells.
Thu Jan 12 00:00:00 EST 2017
Genetic and phenotypic characterization of the novel mouse substrain C57BL/6N Korl with increased body weight.
Scientific reports
Choi KM,Jung J,Cho YM,Kim K,Kim MG,Kim J,Kim H,Shin HJ,Kim HD,Chung ST,Cho S,Chung MW
13-5321 was used in Immunocytochemistry-immunoflourescence to investigate the underlying genetic profiles of a newly developed mouse strain, C57BL/6NKorl.
Fri Oct 27 00:00:00 EDT 2017
Genetic and phenotypic characterization of the novel mouse substrain C57BL/6N Korl with increased body weight.
Scientific reports
Choi KM,Jung J,Cho YM,Kim K,Kim MG,Kim J,Kim H,Shin HJ,Kim HD,Chung ST,Cho S,Chung MW
13-5321 was used in Immunocytochemistry-immunoflourescence to investigate the underlying genetic profiles of a newly developed mouse strain, C57BL/6NKorl.
Fri Oct 27 00:00:00 EDT 2017
Microglial brain region-dependent diversity and selective regional sensitivities to aging.
Nature neuroscience
Grabert K,Michoel T,Karavolos MH,Clohisey S,Baillie JK,Stevens MP,Freeman TC,Summers KM,McColl BW
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Interleukin-13 immune gene therapy prevents CNS inflammation and demyelination via alternative activation of microglia and macrophages.
Glia
Guglielmetti C,Le Blon D,Santermans E,Salas-Perdomo A,Daans J,De Vocht N,Shah D,Hoornaert C,Praet J,Peerlings J,Kara F,Bigot C,Mai Z,Goossens H,Hens N,Hendrix S,Verhoye M,Planas AM,Berneman Z,van der Linden A,Ponsaerts P
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunofluorescence
Thu Dec 01 00:00:00 EST 2016
Microglia are less pro-inflammatory than myeloid infiltrates in the hippocampus of mice exposed to status epilepticus.
Glia
Vinet J,Vainchtein ID,Spano C,Giordano C,Bordini D,Curia G,Dominici M,Boddeke HW,Eggen BJ,Biagini G
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunofluorescence
Mon Aug 01 00:00:00 EDT 2016
Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth.
Stem cells translational medicine
Zheng H,Zou W,Shen J,Xu L,Wang S,Fu YX,Fan W
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Recruited monocytes modulate malaria-induced lung injury through CD36-mediated clearance of sequestered infected erythrocytes.
Journal of leukocyte biology
Lagassé HA,Anidi IU,Craig JM,Limjunyawong N,Poupore AK,Mitzner W,Scott AL
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2016
Lymphatic endothelial lineage assemblage during corneal lymphangiogenesis.
Laboratory investigation; a journal of technical methods and pathology
Connor AL,Kelley PM,Tempero RM
13-5321 was used in Immunofluorescence to determine the precise, regulatory processes necessary for the assembly of proliferating lymphatic endothelial cells.
Tue Mar 01 00:00:00 EST 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Mon Aug 15 00:00:00 EDT 2016
Effects of ketanserin on experimental colitis in mice and macrophage function.
International journal of molecular medicine
Xiao J,Shao L,Shen J,Jiang W,Feng Y,Zheng P,Liu F
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Repulsive guidance molecule a blockade exerts the immunoregulatory function in DCs stimulated with ABP and LPS.
Human vaccines & immunotherapeutics
Xu X,Gao Y,Zhai Z,Zhang S,Shan F,Feng J
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Tue Aug 02 00:00:00 EDT 2016
Thiol peroxiredoxin, a novel allergen from Bombyx mori, modulates functions of macrophages and dendritic cells.
American journal of translational research
Wang H,Hu W,Liang Z,Zeng L,Li J,Yan H,Yang P,Liu Z,Wang L
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Allergy Enhances Neurogenesis and Modulates Microglial Activation in the Hippocampus.
Frontiers in cellular neuroscience
Klein B,Mrowetz H,Thalhamer J,Scheiblhofer S,Weiss R,Aigner L
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunofluorescence
Fri Jul 22 00:00:00 EDT 2016
Stroke sensitivity in the aged: sex chromosome complement vs. gonadal hormones.
Aging
McCullough LD,Mirza MA,Xu Y,Bentivegna K,Steffens EB,Ritzel R,Liu F
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Fri Jul 01 00:00:00 EDT 2016
Epidermal RAF prevents allergic skin disease.
eLife
Raguz J,Jeric I,Niault T,Nowacka JD,Kuzet SE,Rupp C,Fischer I,Biggi S,Borsello T,Baccarini M
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Tue Jul 19 00:00:00 EDT 2016
Intracerebral transplantation of interleukin 13-producing mesenchymal stem cells limits microgliosis, oligodendrocyte loss and demyelination in the cuprizone mouse model.
Journal of neuroinflammation
Le Blon D,Guglielmetti C,Hoornaert C,Quarta A,Daans J,Dooley D,Lemmens E,Praet J,De Vocht N,Reekmans K,Santermans E,Hens N,Goossens H,Verhoye M,Van der Linden A,Berneman Z,Hendrix S,Ponsaerts P
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunofluorescence
Wed Nov 09 00:00:00 EST 2016
Internalization and presentation of myelin antigens by the brain endothelium guides antigen-specific T cell migration.
eLife
Lopes Pinheiro MA,Kamermans A,Garcia-Vallejo JJ,van Het Hof B,Wierts L,O'Toole T,Boeve D,Verstege M,van der Pol SM,van Kooyk Y,de Vries HE,Unger WW
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Thu Jun 23 00:00:00 EDT 2016
Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells.
eLife
Allison KA,Sajti E,Collier JG,Gosselin D,Troutman TD,Stone EL,Hedrick SM,Glass CK
13-5321 was used in Magnetic cell separation to investigate relationship between the strength of antigenic stimulation and the response of mouse CD4+ T cells.
Mon Jul 04 00:00:00 EDT 2016
Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System.
Immunity
Bruttger J,Karram K,Wörtge S,Regen T,Marini F,Hoppmann N,Klein M,Blank T,Yona S,Wolf Y,Mack M,Pinteaux E,Müller W,Zipp F,Binder H,Bopp T,Prinz M,Jung S,Waisman A
13-5321 was used in Flow cytometry/Cell sorting to study how microglia have the potential for efficient self-renewal without the contribution of peripheral myeloid cells, and IL-1R signaling participates in this restorative proliferation process.
Tue Jul 21 00:00:00 EDT 2015
Adaptive Immune Regulation of Mammary Postnatal Organogenesis.
Developmental cell
Plaks V,Boldajipour B,Linnemann JR,Nguyen NH,Kersten K,Wolf Y,Casbon AJ,Kong N,van den Bijgaart RJ,Sheppard D,Melton AC,Krummel MF,Werb Z
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Mon Sep 14 00:00:00 EDT 2015
Benefits of Neuronal Preferential Systemic Gene Therapy for Neurotransmitter Deficiency.
Molecular therapy : the journal of the American Society of Gene Therapy
Lee NC,Muramatsu S,Chien YH,Liu WS,Wang WH,Cheng CH,Hu MK,Chen PW,Tzen KY,Byrne BJ,Hwu WL
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunohistochemistry
Thu Oct 01 00:00:00 EDT 2015
The late endosomal adaptor molecule p14 (LAMTOR2) regulates TGFβ1-mediated homeostasis of Langerhans cells.
The Journal of investigative dermatology
Sparber F,Tripp CH,Komenda K,Scheffler JM,Clausen BE,Huber LA,Romani N,Stoitzner P
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
Intratumoral INF-γ triggers an antiviral state in GL261 tumor cells: a major hurdle to overcome for oncolytic vaccinia virus therapy of cancer.
Molecular therapy oncolytics
Kober C,Weibel S,Rohn S,Kirscher L,Szalay AA
13-5321 was used in Immunohistochemistry to identify microenvironmental factors, which may be decisive for failure or success of oncolytic VACV therapy.
Wed Apr 27 00:00:00 EDT 2016
Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway.
Molecular medicine reports
Huang L,Kong Y,Wang J,Sun J,Shi Q,Qiu YH
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Macrophages Contribute to the Spermatogonial Niche in the Adult Testis.
Cell reports
DeFalco T,Potter SJ,Williams AV,Waller B,Kan MJ,Capel B
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunohistochemistry
Tue Aug 18 00:00:00 EDT 2015
Macrophages Contribute to the Spermatogonial Niche in the Adult Testis.
Cell reports
DeFalco T,Potter SJ,Williams AV,Waller B,Kan MJ,Capel B
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunohistochemistry
Tue Aug 18 00:00:00 EDT 2015
Macrophages Contribute to the Spermatogonial Niche in the Adult Testis.
Cell reports
DeFalco T,Potter SJ,Williams AV,Waller B,Kan MJ,Capel B
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunohistochemistry
Tue Aug 18 00:00:00 EDT 2015
Oxidation by neutrophils-derived HOCl increases immunogenicity of proteins by converting them into ligands of several endocytic receptors involved in antigen uptake by dendritic cells and macrophages.
PloS one
Biedroń R,Konopiński MK,Marcinkiewicz J,Józefowski S
13-5321 was used in an ELISA assay to suggest that a mechanism involving neutrophil-derived hypochlorous acid may enable the immune system to detect pathogens unrecognisable by pattern recognition receptors.
Tue Apr 05 00:00:00 EDT 2016
Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity.
Nature
Westphalen K,Gusarova GA,Islam MN,Subramanian M,Cohen TS,Prince AS,Bhattacharya J
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunofluorescence
Thu Feb 27 00:00:00 EST 2014
High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity.
Nature
Schulz MD,Atay C,Heringer J,Romrig FK,Schwitalla S,Aydin B,Ziegler PK,Varga J,Reindl W,Pommerenke C,Salinas-Riester G,Böck A,Alpert C,Blaut M,Polson SC,Brandl L,Kirchner T,Greten FR,Polson SW,Arkan MC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Thu Oct 23 00:00:00 EDT 2014
C/EBPβ expression is an independent predictor of overall survival in breast cancer patients by MHCII/CD4-dependent mechanism of metastasis formation.
Oncogenesis
Kurzejamska E,Johansson J,Jirström K,Prakash V,Ananthaseshan S,Boon L,Fuxe J,Religa P
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunohistochemistry
Mon Nov 03 00:00:00 EST 2014
Dynamic changes in macrophage activation and proliferation during the development and resolution of intestinal inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Little MC,Hurst RJ,Else KJ
13-5321 was used in Flow cytometry/Cell sorting to study intestinal inflammation and the dynamic changes in macrophage activation and proliferation that occur during this process.
Sat Nov 01 00:00:00 EDT 2014
Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge.
Human vaccines & immunotherapeutics
Wang S,Wu B,Xue J,Wang M,Chen R,Wang B
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Mon Jan 05 00:00:00 EST 2015
BCG vaccine mediated reduction in the MHC-II expression of macrophages and dendritic cells is reversed by activation of Toll-like receptors 7 and 9.
Cellular immunology
Bakhru P,Sirisaengtaksin N,Soudani E,Mukherjee S,Khan A,Jagannath C
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2014
BCG vaccine mediated reduction in the MHC-II expression of macrophages and dendritic cells is reversed by activation of Toll-like receptors 7 and 9.
Cellular immunology
Bakhru P,Sirisaengtaksin N,Soudani E,Mukherjee S,Khan A,Jagannath C
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2014
Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.
PloS one
Xiao GY,Liu IH,Cheng CC,Chang CC,Lee YH,Cheng WT,Wu SC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Thu May 28 00:00:00 EDT 2015
Assessing the role of STAT3 in DC differentiation and autologous DC immunotherapy in mouse models of GBM.
PloS one
Assi H,Espinosa J,Suprise S,Sofroniew M,Doherty R,Zamler D,Lowenstein PR,Castro MG
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunohistochemistry
Fri Jan 23 00:00:00 EST 2015
Assessing the role of STAT3 in DC differentiation and autologous DC immunotherapy in mouse models of GBM.
PloS one
Assi H,Espinosa J,Suprise S,Sofroniew M,Doherty R,Zamler D,Lowenstein PR,Castro MG
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunohistochemistry
Fri Jan 23 00:00:00 EST 2015
Calcitonin gene-related peptide regulates type IV hypersensitivity through dendritic cell functions.
PloS one
Mikami N,Sueda K,Ogitani Y,Otani I,Takatsuji M,Wada Y,Watanabe K,Yoshikawa R,Nishioka S,Hashimoto N,Miyagi Y,Fukada S,Yamamoto H,Tsujikawa K
13-5321 was used in an ELISA assay to study how calcionin gene-related peptide (CGRP) affects dendritic cells in adaptive immunity, showing that CGRP suppresses Th1 cell differentiation via inhibition of IL-12 and down regulates the expression of chemokine receptor and its ligand.
Mon Sep 15 00:00:00 EDT 2014
β(2) integrins inhibit TLR responses by regulating NF-κB pathway and p38 MAPK activation.
European journal of immunology
Yee NK,Hamerman JA
13-5321 was used in Magnetic cell separation to show that deficiency in β(2) integrins causes hyperresponsiveness to TLR stimulation.
Fri Mar 01 00:00:00 EST 2013
Heme oxygenase-1 expression protects the heart from acute injury caused by inducible Cre recombinase.
Laboratory investigation; a journal of technical methods and pathology
Hull TD,Bolisetty S,DeAlmeida AC,Litovsky SH,Prabhu SD,Agarwal A,George JF
13-5321 was used in Flow cytometry/Cell sorting to demonstrate that HO-1 induction prevents the depression of cardiac function imposed by Cre-induced cardiac toxicity.
Thu Aug 01 00:00:00 EDT 2013
Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages.
Blood
He H,Xu J,Warren CM,Duan D,Li X,Wu L,Iruela-Arispe ML
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Thu Oct 11 00:00:00 EDT 2012
Cancer immunoediting by the innate immune system in the absence of adaptive immunity.
The Journal of experimental medicine
O'Sullivan T,Saddawi-Konefka R,Vermi W,Koebel CM,Arthur C,White JM,Uppaluri R,Andrews DM,Ngiow SF,Teng MW,Smyth MJ,Schreiber RD,Bui JD
13-5321 was used in Immunohistochemistry to suggest that in the absence of adaptive immunity, NK cell production of IFN-γ induces M1 macrophages, restoring cancer immunoediting.
Mon Sep 24 00:00:00 EDT 2012
Dendritic cell-specific ablation of the protein tyrosine phosphatase Shp1 promotes Th1 cell differentiation and induces autoimmunity.
Journal of immunology (Baltimore, Md. : 1950)
Kaneko T,Saito Y,Kotani T,Okazawa H,Iwamura H,Sato-Hashimoto M,Kanazawa Y,Takahashi S,Hiromura K,Kusakari S,Kaneko Y,Murata Y,Ohnishi H,Nojima Y,Takagishi K,Matozaki T
13-5321 was used in Flow cytometry/Cell sorting to investigate the molecules that regulate dendritic cells to protect against autoimmunity, showing that loss of Shp1 promotes Th1 cell differentiation and induces autoimmunity.
Fri Jun 01 00:00:00 EDT 2012
Preferential colonization of metastases by oncolytic vaccinia virus strain GLV-1h68 in a human PC-3 prostate cancer model in nude mice.
PloS one
Donat U,Weibel S,Hess M,Stritzker J,Härtl B,Sturm JB,Chen NG,Gentschev I,Szalay AA
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunofluorescence
Tue May 07 00:00:00 EDT 2013
Isolation and characterization of novel murine epiphysis derived mesenchymal stem cells.
PloS one
Cheng CC,Lian WS,Hsiao FS,Liu IH,Lin SP,Lee YH,Chang CC,Xiao GY,Huang HY,Cheng CF,Cheng WT,Wu SC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Fri Sep 07 00:00:00 EDT 2012
The tyrphostin agent AG490 prevents and reverses type 1 diabetes in NOD mice.
PloS one
Davoodi-Semiromi A,Wasserfall CH,Xia CQ,Cooper-DeHoff RM,Wabitsch M,Clare-Salzler M,Atkinson M
13-5321 was used in Flow cytometry/Cell sorting to analyse the development and/or reversal of diabetes, insulitis, adoptive transfer, and other mechanistic studies using NOD mice.
Fri Sep 14 00:00:00 EDT 2012
Chronic IFN-γ production in mice induces anemia by reducing erythrocyte life span and inhibiting erythropoiesis through an IRF-1/PU.1 axis.
Blood
Libregts SF,Gutiérrez L,de Bruin AM,Wensveen FM,Papadopoulos P,van Ijcken W,Ozgür Z,Philipsen S,Nolte MA
13-5321 was used in Flow cytometry/Cell sorting to reveal a molecular mechanism by which chronic exposure to IFN-γ induces expression of IRF-1 and ultimately induces anaemia.
Thu Sep 01 00:00:00 EDT 2011
Emergency granulopoiesis promotes neutrophil-dendritic cell encounters that prevent mouse lung allograft acceptance.
Blood
Kreisel D,Sugimoto S,Zhu J,Nava R,Li W,Okazaki M,Yamamoto S,Ibrahim M,Huang HJ,Toth KA,Ritter JH,Krupnick AS,Miller MJ,Gelman AE
13-5321 was used in Magnetic cell separation to identify granulopoiesis-mediated augmentation of alloimmunity as a novel link between innate and adaptive immune responses after organ transplantation.
Thu Dec 01 00:00:00 EST 2011
Expression of retinaldehyde dehydrogenase enzymes in mucosal dendritic cells and gut-draining lymph node stromal cells is controlled by dietary vitamin A.
Journal of immunology (Baltimore, Md. : 1950)
Molenaar R,Knippenberg M,Goverse G,Olivier BJ,de Vos AF,O'Toole T,Mebius RE
13-5321 was used in Flow cytometry/Cell sorting to show that during postnatal development, dietary vitamin A is essential for the induction of retinaldehyde dehydrogenases in mucosal DCs and MLN stromal cells.
Tue Feb 15 00:00:00 EST 2011
Calcitonin gene-related peptide is an important regulator of cutaneous immunity: effect on dendritic cell and T cell functions.
Journal of immunology (Baltimore, Md. : 1950)
Mikami N,Matsushita H,Kato T,Kawasaki R,Sawazaki T,Kishimoto T,Ogitani Y,Watanabe K,Miyagi Y,Sueda K,Fukada S,Yamamoto H,Tsujikawa K
13-5321 was used in Flow cytometry/Cell sorting to study how calcitonin gene-related peptide effects dendritic and T cells, and regulation of inflammation.
Wed Jun 15 00:00:00 EDT 2011
Establishment of intestinal epithelial cell lines from adult mouse small and large intestinal crypts.
Bioscience, biotechnology, and biochemistry
Iwamoto T,Yamada K,Shimizu M,Totsuka M
13-5321 was used in Flow cytometry/Cell sorting to suggest that the aMoS7 and aMoC1 cell lines can serve as useful tools in analyzing the immunological functions of intestinal epithelial cells (IECs).
Mon Sep 26 00:00:00 EDT 2011
Accumulation of eosinophils in intestine-draining mesenteric lymph nodes occurs after Trichuris muris infection.
Parasite immunology
Svensson M,Bell L,Little MC,DeSchoolmeester M,Locksley RM,Else KJ
13-5321 was used in Flow cytometry/Cell sorting to study the accumulation of eosinophils in intestine-draining mesenteric lymph nodes following Trichuris muris infection.
Sat Jan 01 00:00:00 EST 2011
Alternatively activated macrophages inhibit T-cell proliferation by Stat6-dependent expression of PD-L2.
Blood
Huber S,Hoffmann R,Muskens F,Voehringer D
13-5321 was used in Flow cytometry/Cell sorting to study how IL-4 induced the expression of PD-L2 on CAM, and LPS increased the expression of PD-L1 on alternatively activated macrophages.
Thu Oct 28 00:00:00 EDT 2010
Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks.
The Journal of clinical investigation
Wada T,Ishiwata K,Koseki H,Ishikura T,Ugajin T,Ohnuma N,Obata K,Ishikawa R,Yoshikawa S,Mukai K,Kawano Y,Minegishi Y,Yokozeki H,Watanabe N,Karasuyama H
13-5321 was used in Flow cytometry/Cell sorting to investigate the cellular and molecular mechanisms underlying acquired resistance to Haemaphysalis longicornis ticks in mice.
Sun Aug 01 00:00:00 EDT 2010
Induction of IFN-alphabeta enables Listeria monocytogenes to suppress macrophage activation by IFN-gamma.
The Journal of experimental medicine
Rayamajhi M,Humann J,Penheiter K,Andreasen K,Lenz LL
13-5321 was used in Flow cytometry/Cell sorting to show that IFN-alphabeta produced in response to bacterial infection antagonises the host response to IFN-gamma by down-regulating the IFNGR.
Mon Feb 15 00:00:00 EST 2010
Chloroplast-derived vaccine antigens confer dual immunity against cholera and malaria by oral or injectable delivery.
Plant biotechnology journal
Davoodi-Semiromi A,Schreiber M,Nalapalli S,Verma D,Singh ND,Banks RK,Chakrabarti D,Daniell H
13-5321 was used in Flow cytometry/Cell sorting to further investigate use of chloroplast-derived vaccines against major diseases.
Mon Feb 01 00:00:00 EST 2010
Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity.
The Journal of experimental medicine
Ohnmacht C,Pullner A,King SB,Drexler I,Meier S,Brocker T,Voehringer D
13-5321 was used in Flow cytometry/Cell sorting to demonstrate that dendritic cells play an essential role to protect against fatal CD4+ T cell autoimmunity under steady-state conditions in addition to inducing tolerance.
Mon Mar 16 00:00:00 EDT 2009
Mycobacterium bovis BCG decreases MHC-II expression in vivo on murine lung macrophages and dendritic cells during aerosol infection.
Cellular immunology
Pecora ND,Fulton SA,Reba SM,Drage MG,Simmons DP,Urankar-Nagy NJ,Boom WH,Harding CV
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Flow Cytometry
Fri Jan 02 00:00:00 EST 2009
IL-7 specifies B cell fate at the common lymphoid progenitor to pre-proB transition stage by maintaining early B cell factor expression.
Journal of immunology (Baltimore, Md. : 1950)
Kikuchi K,Kasai H,Watanabe A,Lai AY,Kondo M
13-5321 was used in Flow cytometry/Cell sorting to investigate when IL-7 stimulation is necessary in hemato-/lymphopoiesis in adult mice, showing that IL-7 specifies B cell fate at the common lymphoid progenitor to pre-proB transition stage by maintaining early B cell factor expression.
Tue Jul 01 00:00:00 EDT 2008
Recruitment and in situ renewal regulate rapid accumulation of CD11c+ cells in the lung following intranasal superantigen challenge.
International archives of allergy and immunology
Muralimohan G,Rossi RJ,Vella AT
13-5321 was used in Flow cytometry/Cell sorting to investigate how staphylococcal enterotoxins regulate innate immune cells, showing that it leads to rapid accumulation of CD11c+ cells in the lung following superantigen challenge.
Tue Sep 09 00:00:00 EDT 2008
Loss of T cell receptor-induced Bmi-1 in the KLRG1(+) senescent CD8(+) T lymphocyte.
Proceedings of the National Academy of Sciences of the United States of America
Heffner M,Fearon DT
13-5321 was used in Immunopurification to indicate that Bmi-1 is required for CD8(+) T cell clonal expansion and is positively regulated by receptors that mediate this response.
Tue Aug 14 00:00:00 EDT 2007
Infiltration of inflammatory cells plays an important role in matrix metalloproteinase expression and activation in the heart during sepsis.
The American journal of pathology
Cuenca J,Martín-Sanz P,Alvarez-Barrientos AM,Boscá L,Goren N
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 13-5321-82) in Immunohistochemistry
Wed Nov 01 00:00:00 EST 2006
