Product References
Increased alveolar epithelial TRAF6 via autophagy-dependent TRIM37 degradation mediates particulate matter-induced lung metastasis.
Autophagy
Liu J,Li S,Fei X,Nan X,Shen Y,Xiu H,Cormier SA,Lu C,Guo C,Wang S,Cai Z,Wang P
17-5321-82 was used in Flow cytometry/Cell sorting to demonstrate the central role of PM-induced neutrophil recruitment in promoting lung cancer metastasis.
Sun May 01 00:00:00 EDT 2022
Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota.
Cell
Lima-Junior DS,Krishnamurthy SR,Bouladoux N,Collins N,Han SJ,Chen EY,Constantinides MG,Link VM,Lim AI,Enamorado M,Cataisson C,Gil L,Rao I,Farley TK,Koroleva G,Attig J,Yuspa SH,Fischbach MA,Kassiotis G,Belkaid Y
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Thu Jul 08 00:00:00 EDT 2021
Pleiotropic consequences of metabolic stress for the major histocompatibility complex class II molecule antigen processing and presentation machinery.
Immunity
Clement CC,Nanaware PP,Yamazaki T,Negroni MP,Ramesh K,Morozova K,Thangaswamy S,Graves A,Kim HJ,Li TW,Vigano' M,Soni RK,Gadina M,Tse HY,Galluzzi L,Roche PA,Denzin LK,Stern LJ,Santambrogio L
17-5321-82 was used in Flow cytometry/Cell sorting to highlight a link between glycation reactions and altered MHC class II antigen presentation that may contribute to T2D complications.
Tue Apr 13 00:00:00 EDT 2021
Niche-specific MHC II and PD-L1 regulate CD4+CD8αα+ intraepithelial lymphocyte differentiation.
The Journal of experimental medicine
Moon S,Park Y,Hyeon S,Kim YM,Kim JH,Kim H,Park S,Lee KJ,Koo BK,Ha SJ,Lee SW
17-5321-82 was used in immunohistochemistry (frozen) immunofluorescence to better understand the roles of intestinal epithelial cells.
Mon Apr 05 00:00:00 EDT 2021
CD11b Deficiency Exacerbates Methicillin-Resistant Staphylococcus aureus-Induced Sepsis by Upregulating Inflammatory Responses of Macrophages.
Immune network
Sim H,Jeong D,Kim HI,Pak S,Thapa B,Kwon HJ,Lee K
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Prostaglandin E2 serves a dual role in regulating the migration of dendritic cells.
International journal of molecular medicine
Diao G,Huang J,Zheng X,Sun X,Tian M,Han J,Guo J
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Wip1 regulates the immunomodulatory effects of murine mesenchymal stem cells in type 1 diabetes mellitus via targeting IFN-α/BST2.
Cell death discovery
Zhou N,Liu W,Zhang W,Liu Y,Li X,Wang Y,Zheng R,Zhang Y
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Fri Oct 29 00:00:00 EDT 2021
Topical arginase inhibition decreases growth of cutaneous squamous cell carcinoma.
Scientific reports
Mittal A,Wang M,Vidyarthi A,Yanez D,Pizzurro G,Thakral D,Tracy E,Colegio OR
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Mon May 24 00:00:00 EDT 2021
Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma.
Cell reports
Budhu S,Giese R,Gupta A,Fitzgerald K,Zappasodi R,Schad S,Hirschhorn D,Campesato LF,De Henau O,Gigoux M,Liu C,Mazo G,Deng L,Barker CA,Wolchok JD,Merghoub T
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway.
Journal of neuroinflammation
Duan RN,Yang CL,Du T,Liu A,Wang AR,Sun WJ,Li X,Li JX,Yan CZ,Liu QJ
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Mon Jun 28 00:00:00 EDT 2021
Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway.
Journal of neuroinflammation
Duan RN,Yang CL,Du T,Liu A,Wang AR,Sun WJ,Li X,Li JX,Yan CZ,Liu QJ
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Mon Jun 28 00:00:00 EDT 2021
Frequent amplification of HDAC genes and efficacy of HDAC inhibitor chidamide and PD-1 blockade combination in soft tissue sarcoma.
Journal for immunotherapy of cancer
Que Y,Zhang XL,Liu ZX,Zhao JJ,Pan QZ,Wen XZ,Xiao W,Xu BS,Hong DC,Guo TH,Shen LJ,Fan WJ,Chen HY,Weng DS,Xu HR,Zhou PH,Zhang YZ,Niu XH,Zhang X
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Early activation of the cardiac CX3CL1/CX3CR1 axis delays β-adrenergic-induced heart failure.
Scientific reports
Flamant M,Mougenot N,Balse E,Le Fèvre L,Atassi F,Gautier EL,Le Goff W,Keck M,Nadaud S,Combadière C,Boissonnas A,Pavoine C
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Thu Sep 09 00:00:00 EDT 2021
Expanded renal lymphatics improve recovery following kidney injury.
Physiological reports
Baranwal G,Creed HA,Black LM,Auger A,Quach AM,Vegiraju R,Eckenrode HE,Agarwal A,Rutkowski JM
17-5321-82 was used in Flow cytometry/Cell sorting to demonstrate that increased lymphatic density prior to injury alters the injury recovery response and affords protection from CKD progression.
Mon Nov 01 00:00:00 EDT 2021
PP2Cδ Controls the Differentiation and Function of Dendritic Cells Through Regulating the NSD2/mTORC2/ACLY Pathway.
Frontiers in immunology
Lv N,Jin S,Liang Z,Wu X,Kang Y,Su L,Dong Y,Wang B,Ma T,Shi L
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Mon Feb 28 00:00:00 EST 2022
Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis.
Frontiers in immunology
Yang P,Tian H,Zou YR,Chambon P,Ichinose H,Honig G,Diamond B,Kim SJ
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Glufosinate constrains synchronous and metachronous metastasis by promoting anti-tumor macrophages.
EMBO molecular medicine
Menga A,Serra M,Todisco S,Riera-Domingo C,Ammarah U,Ehling M,Palmieri EM,Di Noia MA,Gissi R,Favia M,Pierri CL,Porporato PE,Castegna A,Mazzone M
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Wed Oct 07 00:00:00 EDT 2020
Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2).
Cancer immunology research
Huetter J,Gritzan U,Gutcher I,Doecke WD,Luetke-Eversloh MV,Golfier S,Roider HG,Frisk AL,Hunter J,Pow A,Drake A,Levine Z,Levy O,Azulay M,Barbiro I,Cojocaru G,Vaknin I,Kreft B,Roese L
17-5321 was used in Flow cytometry/Cell sorting to show that BAY 1905254 is a potential drug candidate for cancer immunotherapy.
Wed Jul 01 00:00:00 EDT 2020
E6‑regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16‑positive cervical lesions.
International journal of oncology
Huang J,Diao G,Zhang Q,Chen Y,Han J,Guo J
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Role of dendritic cell-mediated immune response in oral homeostasis: A new mechanism of osteonecrosis of the jaw.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Elsayed R,Kurago Z,Cutler CW,Arce RM,Gerber J,Celis E,Sultan H,Elashiry M,Meghil M,Sun C,Auersvald CM,Awad ME,Zeitoun R,Elsayed R,Eldin M Elshikh M,Isales C,Elsalanty ME
17-5321-82 was used in Flow Cytometry to conclude that the mechanism of Zol-induced osteonecrosis of the jaw involves disruption of DC immune functions required to clear bacterial infection and activate T cell effector response.
Sat Feb 01 00:00:00 EST 2020
Role of dendritic cell-mediated immune response in oral homeostasis: A new mechanism of osteonecrosis of the jaw.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Elsayed R,Kurago Z,Cutler CW,Arce RM,Gerber J,Celis E,Sultan H,Elashiry M,Meghil M,Sun C,Auersvald CM,Awad ME,Zeitoun R,Elsayed R,Eldin M Elshikh M,Isales C,Elsalanty ME
17-5321-82 was used in Flow Cytometry to conclude that the mechanism of Zol-induced osteonecrosis of the jaw involves disruption of DC immune functions required to clear bacterial infection and activate T cell effector response.
Sat Feb 01 00:00:00 EST 2020
High-fat diet induced central adiposity (visceral fat) is associated with increased fibrosis and decreased immune cellularity of the mesenteric lymph node in mice.
European journal of nutrition
Magnuson AM,Regan DP,Booth AD,Fouts JK,Solt CM,Hill JL,Dow SW,Foster MT
17-5321-82 was used in Flow Cytometry to investigate if lymph nodes are inherently distinct and differentially respond to diet-induced obesity much like the adipose depots they reside in.
Mon Jun 01 00:00:00 EDT 2020
IFN-β signalling regulates RAW 264.7 macrophage activation, cytokine production, and killing activity.
Innate immunity
Karimi Y,Giles EC,Vahedi F,Chew MV,Nham T,Loukov D,Lee AJ,Bowdish DM,Ashkar AA
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Dietary Glucose Consumption Promotes RALDH Activity in Small Intestinal CD103+CD11b+ Dendritic Cells.
Frontiers in immunology
Ko HJ,Hong SW,Verma R,Jung J,Lee M,Kim N,Kim D,Surh CD,Kim KS,Rudra D,Im SH
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Mon Apr 19 00:00:00 EDT 2021
GDF3 Protects Mice against Sepsis-Induced Cardiac Dysfunction and Mortality by Suppression of Macrophage Pro-Inflammatory Phenotype.
Cells
Wang L,Li Y,Wang X,Wang P,Essandoh K,Cui S,Huang W,Mu X,Liu Z,Wang Y,Peng T,Fan GC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Fri Jan 03 00:00:00 EST 2020
Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells.
Nature communications
Lucas B,White AJ,Cosway EJ,Parnell SM,James KD,Jones ND,Ohigashi I,Takahama Y,Jenkinson WE,Anderson G
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Mon May 04 00:00:00 EDT 2020
Smooth muscle-derived progenitor cell myofibroblast differentiation through KLF4 downregulation promotes arterial remodeling and fibrosis.
JCI insight
Lu S,Jolly AJ,Strand KA,Dubner AM,Mutryn MF,Moulton KS,Nemenoff RA,Majesky MW,Weiser-Evans MC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Thu Dec 03 00:00:00 EST 2020
Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses.
Scientific reports
Hrdý J,Alard J,Couturier-Maillard A,Boulard O,Boutillier D,Delacre M,Lapadatescu C,Cesaro A,Blanc P,Pot B,Ryffel B,Chamaillard M,Grangette C
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Tue Mar 24 00:00:00 EDT 2020
Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses.
Scientific reports
Hrdý J,Alard J,Couturier-Maillard A,Boulard O,Boutillier D,Delacre M,Lapadatescu C,Cesaro A,Blanc P,Pot B,Ryffel B,Chamaillard M,Grangette C
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Tue Mar 24 00:00:00 EDT 2020
Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection.
Cell reports
Dokoshi T,Zhang LJ,Li F,Nakatsuji T,Butcher A,Yoshida H,Shimoda M,Okada Y,Gallo RL
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Tue Jan 07 00:00:00 EST 2020
Ly6cLo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation.
Scientific reports
Alkhani A,Levy CS,Tsui M,Rosenberg KA,Polovina K,Mattis AN,Mack M,Van Dyken S,Wang BM,Maher JJ,Nijagal A
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Tue Apr 28 00:00:00 EDT 2020
MiR-103 protects from recurrent spontaneous abortion via inhibiting STAT1 mediated M1 macrophage polarization.
International journal of biological sciences
Zhu X,Liu H,Zhang Z,Wei R,Zhou X,Wang Z,Zhao L,Guo Q,Zhang Y,Chu C,Wang L,Li X
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Fri Nov 12 00:00:00 EST 2021
Cancer cell-intrinsic expression of MHC II in lung cancer cell lines is actively restricted by MEK/ERK signaling and epigenetic mechanisms.
Journal for immunotherapy of cancer
Neuwelt AJ,Kimball AK,Johnson AM,Arnold BW,Bullock BL,Kaspar RE,Kleczko EK,Kwak JW,Wu MH,Heasley LE,Doebele RC,Li HY,Nemenoff RA,Clambey ET
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Immunomodulatory Effects of Recombinant Mycobacterium smegmatis Expressing Antigen-85B Epitopes in Infected J774A.1 Murine Macrophages.
Pathogens (Basel, Switzerland)
Kadir NA,Acosta A,Sarmiento ME,Norazmi MN
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Sun Nov 29 00:00:00 EST 2020
Artificial Mini Dendritic Cells Boost T Cell-Based Immunotherapy for Ovarian Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Cheng S,Xu C,Jin Y,Li Y,Zhong C,Ma J,Yang J,Zhang N,Li Y,Wang C,Yang Z,Wang Y
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Optimized Protocol for Isolation of Small Extracellular Vesicles from Human and Murine Lymphoid Tissues.
International journal of molecular sciences
Bordas M,Genard G,Ohl S,Nessling M,Richter K,Roider T,Dietrich S,Maaß KK,Seiffert M
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Tue Aug 04 00:00:00 EDT 2020
Skeletal muscle healing by M1-like macrophages produced by transient expression of exogenous GM-CSF.
Stem cell research & therapy
Martins L,Gallo CC,Honda TSB,Alves PT,Stilhano RS,Rosa DS,Koh TJ,Han SW
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Fri Nov 06 00:00:00 EST 2020
Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine.
Nature communications
Campesato LF,Budhu S,Tchaicha J,Weng CH,Gigoux M,Cohen IJ,Redmond D,Mangarin L,Pourpe S,Liu C,Zappasodi R,Zamarin D,Cavanaugh J,Castro AC,Manfredi MG,McGovern K,Merghoub T,Wolchok JD
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Tue Aug 11 00:00:00 EDT 2020
Nuclear imaging-guided PD-L1 blockade therapy increases effectiveness of cancer immunotherapy.
Journal for immunotherapy of cancer
Gao H,Wu Y,Shi J,Zhang X,Liu T,Hu B,Jia B,Wan Y,Liu Z,Wang F
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Fri Jun 19 00:00:00 EDT 2020
Mesenchymal stromal cells induce distinct myeloid-derived suppressor cells in inflammation.
JCI insight
Lee HJ,Ko JH,Kim HJ,Jeong HJ,Oh JY
17-5321 was used in Flow cytometry/Cell sorting to reveal that suppression of prostaglandin E2 (PGE2) and HGF secretion in MSCs by siRNA transfection partially reversed the effects of MSCs on MDSC differentiation.
Thu Jun 18 00:00:00 EDT 2020
Aire-dependent genes undergo Clp1-mediated 3'UTR shortening associated with higher transcript stability in the thymus.
eLife
Guyon C,Jmari N,Padonou F,Li YC,Ucar O,Fujikado N,Coulpier F,Blanchet C,Root DE,Giraud M
17-5321 was used in Flow cytometry/Cell sorting to understand how Aire-dependent genes in thymic medullary epithelial cells achieve higher transcript stability and expression through Clp1-mediated shortening of 3'UTR transcript isoforms.
Wed Apr 29 00:00:00 EDT 2020
CDK4/6 inhibition promotes immune infiltration in ovarian cancer and synergizes with PD-1 blockade in a B cell-dependent manner.
Theranostics
Zhang QF,Li J,Jiang K,Wang R,Ge JL,Yang H,Liu SJ,Jia LT,Wang L,Chen BL
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Tue Jun 01 00:00:00 EDT 2021
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Mon Jun 29 00:00:00 EDT 2020
Polyanhydride Nanoparticles Induce Low Inflammatory Dendritic Cell Activation Resulting in CD8+ T Cell Memory and Delayed Tumor Progression.
International journal of nanomedicine
Darling R,Senapati S,Christiansen J,Liu L,Ramer-Tait AE,Narasimhan B,Wannemuehler M
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Mon Dec 07 00:00:00 EST 2020
Toxin-Triggered Interleukin-1 Receptor Signaling Enables Early-Life Discrimination of Pathogenic versus Commensal Skin Bacteria.
Cell host & microbe
Leech JM,Dhariwala MO,Lowe MM,Chu K,Merana GR,Cornuot C,Weckel A,Ma JM,Leitner EG,Gonzalez JR,Vasquez KS,Diep BA,Scharschmidt TC
17-5321-82 was used in Flow cytometry/Cell sorting to study how skin colonization by commensal Staphylococcus epidermidis facilitates immune tolerance preferentially in neonates via induction of antigen-specific regulatory T cells.
Wed Dec 11 00:00:00 EST 2019
Toxin-Triggered Interleukin-1 Receptor Signaling Enables Early-Life Discrimination of Pathogenic versus Commensal Skin Bacteria.
Cell host & microbe
Leech JM,Dhariwala MO,Lowe MM,Chu K,Merana GR,Cornuot C,Weckel A,Ma JM,Leitner EG,Gonzalez JR,Vasquez KS,Diep BA,Scharschmidt TC
17-5321-82 was used in Flow cytometry/Cell sorting to study how skin colonization by commensal Staphylococcus epidermidis facilitates immune tolerance preferentially in neonates via induction of antigen-specific regulatory T cells.
Wed Dec 11 00:00:00 EST 2019
cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity.
The Journal of clinical investigation
Wang Z,Chen J,Hu J,Zhang H,Xu F,He W,Wang X,Li M,Lu W,Zeng G,Zhou P,Huang P,Chen S,Li W,Xia LP,Xia X
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Tue Aug 13 00:00:00 EDT 2019
Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection-Induced Neuropathic Pain.
Pain research & management
Sheng WS,Chauhan P,Hu S,Prasad S,Lokensgard JR
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Mon Dec 16 00:00:00 EST 2019
MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.
Journal for immunotherapy of cancer
Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Thu Nov 28 00:00:00 EST 2019
Bacteroides fragilis polysaccharide A induces IL-10 secreting B and T cells that prevent viral encephalitis.
Nature communications
Ramakrishna C,Kujawski M,Chu H,Li L,Mazmanian SK,Cantin EM
17-5321 was used in Flow cytometry/Cell sorting to study polysaccharide A as an immunomodulatory symbiosis factor whcih coordinates anti-inflammatory responses during viral infections.
Tue May 14 00:00:00 EDT 2019
Expression of the Phosphatase Ppef2 Controls Survival and Function of CD8+ Dendritic Cells.
Frontiers in immunology
Zwick M,Ulas T,Cho YL,Ried C,Grosse L,Simon C,Bernhard C,Busch DH,Schultze JL,Buchholz VR,Stutte S,Brocker T
17-5321-82 was used in Flow Cytometry to suggest that Ppef2 is crucial to support survival of immature CD8+ DCs, while Ppef2 down-regulation during DC-maturation limits T cell responses.
Tue Oct 27 00:00:00 EDT 2020
TGFβ depletion does neither modulate acute E. coli-induced inflammatory immune responses nor impair the protective effect by chronic filarial infection.
GMS infectious diseases
Buerfent BC,Ajendra J,Stamminger W,Gondorf F,Hoerauf A,Hübner MP
17-5321-82 was used in Flow Cytometry to investigate whether this protective effect is dependent on TGFβ signaling and whether depletion of TGFβ before E. coli challenge alters the early course of sepsis per se.
Thu Oct 01 00:00:00 EDT 2020
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
An Interleukin-25-Mediated Autoregulatory Circuit in Keratinocytes Plays a Pivotal Role in Psoriatic Skin Inflammation.
Immunity
Xu M,Lu H,Lee YH,Wu Y,Liu K,Shi Y,An H,Zhang J,Wang X,Lai Y,Dong C
17-5321 was used in Flow cytometry/Cell sorting to study the initiation and maintenance of chronic skin inflammation in psoriasis.
Tue Apr 17 00:00:00 EDT 2018
Co-inhibitory Molecule B7 Superfamily Member 1 Expressed by Tumor-Infiltrating Myeloid Cells Induces Dysfunction of Anti-tumor CD8+ T Cells.
Immunity
Li J,Lee Y,Li Y,Jiang Y,Lu H,Zang W,Zhao X,Liu L,Chen Y,Tan H,Yang Z,Zhang MQ,Mak TW,Ni L,Dong C
17-5321 was used in Flow cytometry/Cell sorting to demonstrate that increased B7S1 expression in myeloid cells from human hepatocellular carcinoma is correlated with CD8+ T cell dysfunction.
Tue Apr 17 00:00:00 EDT 2018
Macrophage-specific MHCII expression is regulated by a remote Ciita enhancer controlled by NFAT5.
The Journal of experimental medicine
Buxadé M,Huerga Encabo H,Riera-Borrull M,Quintana-Gallardo L,López-Cotarelo P,Tellechea M,Martínez-Martínez S,Redondo JM,Martín-Caballero J,Flores JM,Bosch E,Rodríguez-Fernández JL,Aramburu J,López-Rodríguez C
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Mon Nov 05 00:00:00 EST 2018
Tamm-Horsfall Protein Regulates Mononuclear Phagocytes in the Kidney.
Journal of the American Society of Nephrology : JASN
Micanovic R,Khan S,Janosevic D,Lee ME,Hato T,Srour EF,Winfree S,Ghosh J,Tong Y,Rice SE,Dagher PC,Wu XR,El-Achkar TM
17-5321 was used in Flow cytometry/Cell sorting to suggest that interstitial THP positively regulates mononuclear phagocyte number, plasticity, and phagocytic activity.
Thu Mar 01 00:00:00 EST 2018
Antigen-specific airway IL-33 production depends on FcγR-mediated incorporation of the antigen by alveolar macrophages in sensitized mice.
Immunology
Nabe T,Matsuda M,Ishida T,Tsujimoto N,Kido H,Kanaya H,Takahashi H,Takemoto N,Nomura M,Ishihara K,Akiba S,Mizutani N
17-5321 was used in Flow cytometry/Cell sorting to demonstrate that the administered OVA in the lung bound antigen-specific IgG Ab, and then alveolar macrophages incorporated the immune complex through FcγRII/III on the cell surface, resulting in IL-33 production in sensitized mice.
Sat Sep 01 00:00:00 EDT 2018
Construction and Characterization of Adenovirus Vectors Encoding Aspartate-β-Hydroxylase to Preliminary Application in Immunotherapy of Hepatocellular Carcinoma.
Journal of immunology research
Zhou Y,Liu F,Li C,Shi G,Xu X,Luo X,Zhang Y,Fu J,Zeng A,Chen L
17-5321 was used in Flow cytometry/Cell sorting to explored the anti-tumour effects of dendritic cell vaccines harbouring aspartate-Β-hydroxylase.
Mon Nov 05 00:00:00 EST 2018
FACS isolation of live mouse eosinophils at high purity via a protocol that does not target Siglec F.
Journal of immunological methods
Geslewitz WE,Percopo CM,Rosenberg HF
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2018
Myeloid apolipoprotein E controls dendritic cell antigen presentation and T cell activation.
Nature communications
Bonacina F,Coe D,Wang G,Longhi MP,Baragetti A,Moregola A,Garlaschelli K,Uboldi P,Pellegatta F,Grigore L,Da Dalt L,Annoni A,Gregori S,Xiao Q,Caruso D,Mitro N,Catapano AL,Marelli-Berg FM,Norata GD
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Mon Aug 06 00:00:00 EDT 2018
CD4+ T cells are activated in regional lymph nodes and migrate to skin to initiate lymphedema.
Nature communications
García Nores GD,Ly CL,Cuzzone DA,Kataru RP,Hespe GE,Torrisi JS,Huang JJ,Gardenier JC,Savetsky IL,Nitti MD,Yu JZ,Rehal S,Mehrara BJ
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Thu May 17 00:00:00 EDT 2018
Lin-CCR2+ hematopoietic stem and progenitor cells overcome resistance to PD-1 blockade.
Nature communications
Flores CT,Wildes TJ,Drake JA,Moore GL,Dean BD,Abraham RS,Mitchell DA
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Wed Oct 17 00:00:00 EDT 2018
Lin-CCR2+ hematopoietic stem and progenitor cells overcome resistance to PD-1 blockade.
Nature communications
Flores CT,Wildes TJ,Drake JA,Moore GL,Dean BD,Abraham RS,Mitchell DA
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Wed Oct 17 00:00:00 EDT 2018
Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis.
mBio
Gralinski LE,Sheahan TP,Morrison TE,Menachery VD,Jensen K,Leist SR,Whitmore A,Heise MT,Baric RS
17-5321 was used in Flow cytometry/Cell sorting to study complement signalling as regulating a proinflammatory response to SARS-CoV infection.
Tue Oct 09 00:00:00 EDT 2018
Compensation between CSF1R+ macrophages and Foxp3+ Treg cells drives resistance to tumor immunotherapy.
JCI insight
Gyori D,Lim EL,Grant FM,Spensberger D,Roychoudhuri R,Shuttleworth SJ,Okkenhaug K,Stephens LR,Hawkins PT
17-5321 was used in Flow cytometry/Cell sorting to study the role of CSF1R dependent TAMs on the immunosuppressive tumour microenvironment.
Thu Jun 07 00:00:00 EDT 2018
Live imaging and tracking of genome regions in CRISPR/dCas9 knock-in mice.
Genome biology
Duan J,Lu G,Hong Y,Hu Q,Mai X,Guo J,Si X,Wang F,Zhang Y
17-5321 was used in Flow cytometry/Cell sorting to generate and characterise a mouse strain with dCas9-EGFP ubiquitously expressed in various tissues.
Thu Nov 08 00:00:00 EST 2018
IL-31 is crucial for induction of pruritus, but not inflammation, in contact hypersensitivity.
Scientific reports
Takamori A,Nambu A,Sato K,Yamaguchi S,Matsuda K,Numata T,Sugawara T,Yoshizaki T,Arae K,Morita H,Matsumoto K,Sudo K,Okumura K,Kitaura J,Matsuda H,Nakae S
17-5321 was used in Flow cytometry/Cell sorting to investigate the role of IL-31 in development of contact dermatitis/contact hypersensitivity (CHS), which is mediated by hapten-specific T cells, including Th2 cells, in IL-31-deficient (Il31-/-) mice.
Fri Apr 27 00:00:00 EDT 2018
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
The Journal of clinical investigation
Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells.
Frontiers in immunology
Bai WJ,Li CG,Zhang CC,Xu LH,Zeng QZ,Hu B,Hong Z,He XH,Ouyang DY
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Diet-induced obesity causes visceral, but not subcutaneous, lymph node hyperplasia via increases in specific immune cell populations.
Cell proliferation
Magnuson AM,Regan DP,Fouts JK,Booth AD,Dow SW,Foster MT
17-5321 was used in Flow cytometry/Cell sorting to investigate whether secondary lymphatics within visceral adiposity contribute to disease risk.
Sun Oct 01 00:00:00 EDT 2017
Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice.
Neurobiology of disease
MacPherson KP,Sompol P,Kannarkat GT,Chang J,Sniffen L,Wildner ME,Norris CM,Tansey MG
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
B cell subsets are modulated during allergic airway inflammation but are not required for the development of respiratory tolerance in a murine model.
European journal of immunology
Habener A,Behrendt AK,Skuljec J,Jirmo AC,Meyer-Bahlburg A,Hansen G
17-5321 was used in Flow cytometry/Cell sorting to investigate how B cells are affected by induction of allergic airway inflammation and respiratory tolerance.
Wed Mar 01 00:00:00 EST 2017
Discrimination of the heterogeneity of bone marrow‑derived dendritic cells.
Molecular medicine reports
Wang J,Dai X,Hsu C,Ming C,He Y,Zhang J,Wei L,Zhou P,Wang CY,Yang J,Gong N
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Wed Nov 01 00:00:00 EDT 2017
Loss of IRF2BP2 in Microglia Increases Inflammation and Functional Deficits after Focal Ischemic Brain Injury.
Frontiers in cellular neuroscience
Cruz SA,Hari A,Qin Z,Couture P,Huang H,Lagace DC,Stewart AFR,Chen HH
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Thu Mar 17 00:00:00 EDT 2022
Role of a novel immune modulating DDR2-expressing population in silica-induced pulmonary fibrosis.
PloS one
McDonald LT,Johnson SD,Russell DL,Young MRI,LaRue AC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Mon Sep 25 00:00:00 EDT 2017
Microglial brain region-dependent diversity and selective regional sensitivities to aging.
Nature neuroscience
Grabert K,Michoel T,Karavolos MH,Clohisey S,Baillie JK,Stevens MP,Freeman TC,Summers KM,McColl BW
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Lung epithelium and myeloid cells cooperate to clear acute pneumococcal infection.
Mucosal immunology
Dudek M,Puttur F,Arnold-Schrauf C,Kühl AA,Holzmann B,Henriques-Normark B,Berod L,Sparwasser T
17-5321 was used in Flow cytometry/Cell sorting to investigate the extent to which MyD88 signaling is required to control S. pneumoniae infection, showing that lung epithelium and myeloid cells cooperate to clear infection.
Thu Sep 01 00:00:00 EDT 2016
Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth.
Stem cells translational medicine
Zheng H,Zou W,Shen J,Xu L,Wang S,Fu YX,Fan W
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Recruited monocytes modulate malaria-induced lung injury through CD36-mediated clearance of sequestered infected erythrocytes.
Journal of leukocyte biology
Lagassé HA,Anidi IU,Craig JM,Limjunyawong N,Poupore AK,Mitzner W,Scott AL
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Mon Aug 15 00:00:00 EDT 2016
G-CSF-Induced Suppressor IL-10+ Neutrophils Promote Regulatory T Cells That Inhibit Graft-Versus-Host Disease in a Long-Lasting and Specific Way.
Journal of immunology (Baltimore, Md. : 1950)
Perobelli SM,Mercadante AC,Galvani RG,Gonçalves-Silva T,Alves AP,Pereira-Neves A,Benchimol M,Nóbrega A,Bonomo A
17-5321 was used in Flow cytometry/Cell sorting to study the role of incoming IL-10+ neutrophils from G-CSF-treated donor spleen in inhibiting acute graft-versus-host disease.
Tue Nov 01 00:00:00 EDT 2016
Effects of ketanserin on experimental colitis in mice and macrophage function.
International journal of molecular medicine
Xiao J,Shao L,Shen J,Jiang W,Feng Y,Zheng P,Liu F
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
High-Risk Corneal Graft Rejection in the Setting of Previous Corneal Herpes Simplex Virus (HSV)-1 Infection.
Investigative ophthalmology & visual science
Kuffova L,Knickelbein JE,Yu T,Medina C,Amescua G,Rowe AM,Hendricks RL,Forrester JV
17-5321-82 was used in Immunohistochemistry-immunofluorescence to investigate the immunologic mechanisms underlying accelerated corneal graft rejection using a mouse model of keratitis.
Fri Apr 01 00:00:00 EDT 2016
Repulsive guidance molecule a blockade exerts the immunoregulatory function in DCs stimulated with ABP and LPS.
Human vaccines & immunotherapeutics
Xu X,Gao Y,Zhai Z,Zhang S,Shan F,Feng J
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Tue Aug 02 00:00:00 EDT 2016
Thiol peroxiredoxin, a novel allergen from Bombyx mori, modulates functions of macrophages and dendritic cells.
American journal of translational research
Wang H,Hu W,Liang Z,Zeng L,Li J,Yan H,Yang P,Liu Z,Wang L
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Stroke sensitivity in the aged: sex chromosome complement vs. gonadal hormones.
Aging
McCullough LD,Mirza MA,Xu Y,Bentivegna K,Steffens EB,Ritzel R,Liu F
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Fri Jul 01 00:00:00 EDT 2016
Epidermal RAF prevents allergic skin disease.
eLife
Raguz J,Jeric I,Niault T,Nowacka JD,Kuzet SE,Rupp C,Fischer I,Biggi S,Borsello T,Baccarini M
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Tue Jul 19 00:00:00 EDT 2016
Internalization and presentation of myelin antigens by the brain endothelium guides antigen-specific T cell migration.
eLife
Lopes Pinheiro MA,Kamermans A,Garcia-Vallejo JJ,van Het Hof B,Wierts L,O'Toole T,Boeve D,Verstege M,van der Pol SM,van Kooyk Y,de Vries HE,Unger WW
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Thu Jun 23 00:00:00 EDT 2016
L-Arginine supplementation inhibits the growth of breast cancer by enhancing innate and adaptive immune responses mediated by suppression of MDSCs in vivo.
BMC cancer
Cao Y,Feng Y,Zhang Y,Zhu X,Jin F
17-5321 was used in Flow cytometry/Cell sorting to study the effects of L-Arg treatment on inhibition of tumour growth and immunological function.
Wed Jun 01 00:00:00 EDT 2016
Chronic spinal cord injury attenuates influenza virus-specific antiviral immunity.
Journal of neuroinflammation
Bracchi-Ricard V,Zha J,Smith A,Lopez-Rodriguez DM,Bethea JR,Andreansky S
17-5321 was used in Flow cytometry/Cell sorting to show that chronic SCI causes severe morbidity and mortality in mice infected with influenza A virus by compromising antibody and CD8+ T cell responses.
Tue May 31 00:00:00 EDT 2016
CD4+ T Cells Are as Protective as CD8+ T Cells against Rickettsia typhi Infection by Activating Macrophage Bactericidal Activity.
PLoS neglected tropical diseases
Moderzynski K,Papp S,Rauch J,Heine L,Kuehl S,Richardt U,Fleischer B,Osterloh A
17-5321 was used in Flow cytometry/Cell sorting to demonstrate that CD4+ T cells are as protective as CD8+ T cells against R. typhi, provided that CD4+ TH1 effector cells are present in time to support bactericidal activity of phagocytes via the release of IFNγ and other factors.
Tue Nov 01 00:00:00 EDT 2016
Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke.
Nature communications
Szalay G,Martinecz B,Lénárt N,Környei Z,Orsolits B,Judák L,Császár E,Fekete R,West BL,Katona G,Rózsa B,Dénes Á
17-5321 was used in Flow cytometry/Cell sorting to investigate the influence of microglia on neuronal activity and survival in the injured brain in vivo.
Tue May 03 00:00:00 EDT 2016
Macrophage and epithelial cell H-ferritin expression regulates renal inflammation.
Kidney international
Bolisetty S,Zarjou A,Hull TD,Traylor AM,Perianayagam A,Joseph R,Kamal AI,Arosio P,Soares MP,Jeney V,Balla J,George JF,Agarwal A
17-5321 was used in Flow cytometry/Cell sorting to explore the critical role of the heavy subunit of ferritin in tubular-macrophage cross-talk during kidney injury.
Wed Jul 01 00:00:00 EDT 2015
Adaptive Immune Regulation of Mammary Postnatal Organogenesis.
Developmental cell
Plaks V,Boldajipour B,Linnemann JR,Nguyen NH,Kersten K,Wolf Y,Casbon AJ,Kong N,van den Bijgaart RJ,Sheppard D,Melton AC,Krummel MF,Werb Z
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Mon Sep 14 00:00:00 EDT 2015
The late endosomal adaptor molecule p14 (LAMTOR2) regulates TGFβ1-mediated homeostasis of Langerhans cells.
The Journal of investigative dermatology
Sparber F,Tripp CH,Komenda K,Scheffler JM,Clausen BE,Huber LA,Romani N,Stoitzner P
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
Immune quiescence of the brain is set by astroglial connexin 43.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Boulay AC,Mazeraud A,Cisternino S,Saubaméa B,Mailly P,Jourdren L,Blugeon C,Mignon V,Smirnova M,Cavallo A,Ezan P,Avé P,Dingli F,Loew D,Vieira P,Chrétien F,Cohen-Salmon M
17-5321 was used in Flow cytometry/Cell sorting to demonstrate that connexin 43 (Cx43) is a new astroglial factor promoting the immune quiescence of the brain.
Wed Mar 11 00:00:00 EDT 2015
TSLP expression: analysis with a ZsGreen TSLP reporter mouse.
Journal of immunology (Baltimore, Md. : 1950)
Dewas C,Chen X,Honda T,Junttila I,Linton J,Udey MC,Porcella SF,Sturdevant DE,Feigenbaum L,Koo L,Williams J,Paul WE
17-5321 was used in Flow cytometry/Cell sorting to suggest that TSLP may be involved in a positive feedback loop in allergic inflammatory conditions by both inducing Th2 differentiation and being activated by these cells.
Sun Feb 01 00:00:00 EST 2015
Cornea-infiltrating and lymph node dendritic cells contribute to CD4+ T cell expansion after herpes simplex virus-1 ocular infection.
Journal of immunology (Baltimore, Md. : 1950)
Buela KA,Hendricks RL
17-5321 was used in Flow cytometry/Cell sorting to determine the contribution of cornea resident, cornea-infiltrating, and DLN resident dendritic cells (DC) to CD4(+) T cell expansion in DLNs and restimulation in corneas.
Thu Jan 01 00:00:00 EST 2015
Epidermal keratinocytes initiate wound healing and pro-inflammatory immune responses following percutaneous schistosome infection.
International journal for parasitology
Bourke CD,Prendergast CT,Sanin DE,Oulton TE,Hall RJ,Mountford AP
17-5321 was used in Flow cytometry/Cell sorting to indicate that S.mansoni cercariae and their excretory/secretory products act directly upon epidermal keratinocytes.
Sun Mar 01 00:00:00 EST 2015
Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway.
Molecular medicine reports
Huang L,Kong Y,Wang J,Sun J,Shi Q,Qiu YH
17-5321 was used in an ELISA assay to demonstrate a therapeutic consequence of blocking the B7-1/CD28 signalling pathway for autoimmune disorders.
Tue Sep 01 00:00:00 EDT 2015
Macrophages Contribute to the Spermatogonial Niche in the Adult Testis.
Cell reports
DeFalco T,Potter SJ,Williams AV,Waller B,Kan MJ,Capel B
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Tue Aug 18 00:00:00 EDT 2015
High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity.
Nature
Schulz MD,Atay C,Heringer J,Romrig FK,Schwitalla S,Aydin B,Ziegler PK,Varga J,Reindl W,Pommerenke C,Salinas-Riester G,Böck A,Alpert C,Blaut M,Polson SC,Brandl L,Kirchner T,Greten FR,Polson SW,Arkan MC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Thu Oct 23 00:00:00 EDT 2014
Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity.
Nature
Westphalen K,Gusarova GA,Islam MN,Subramanian M,Cohen TS,Prince AS,Bhattacharya J
17-5321 was used in Immunofluorescence to show that a subset of alveolar macrophages (AMs) attached to the alveolar wall form connexin 43 (Cx43)-containing gap junction channels with the epithelium.
Thu Feb 27 00:00:00 EST 2014
Secretion of IL-16 through TNFR1 and calpain-caspase signaling contributes to MRSA pneumonia.
Mucosal immunology
Ahn DS,Parker D,Planet PJ,Nieto PA,Bueno SM,Prince A
17-5321 was used in Flow cytometry/Cell sorting to study the role of IL-16 in disease progression of S. aureus pneumonia.
Sat Nov 01 00:00:00 EDT 2014
The N-terminal domain of NLRC5 confers transcriptional activity for MHC class I and II gene expression.
Journal of immunology (Baltimore, Md. : 1950)
Neerincx A,Jakobshagen K,Utermöhlen O,Büning H,Steimle V,Kufer TA
17-5321 was used in Flow cytometry/Cell sorting to demonstrate the function of NLRC5 and CIITA in MHC gene regulation.
Mon Sep 15 00:00:00 EDT 2014
Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways.
Journal of immunology (Baltimore, Md. : 1950)
Williams JA,Zhang J,Jeon H,Nitta T,Ohigashi I,Klug D,Kruhlak MJ,Choudhury B,Sharrow SO,Granger L,Adams A,Eckhaus MA,Jenkinson SR,Richie ER,Gress RE,Takahama Y,Hodes RJ
17-5321 was used in Flow cytometry/Cell sorting to reveal two costimulatory signalling pathways necessary for thymus crosstalk and the induction of tolerance.
Wed Jan 15 00:00:00 EST 2014
Oral combined therapy with probiotics and alloantigen induces B cell-dependent long-lasting specific tolerance.
Journal of immunology (Baltimore, Md. : 1950)
Mercadante AC,Perobelli SM,Alves AP,Gonçalves-Silva T,Mello W,Gomes-Santos AC,Miyoshi A,Azevedo V,Faria AM,Bonomo A
17-5321 was used in Flow cytometry/Cell sorting to suggest that combined therapy is a promising strategy for prevention of GVHD with preservation of graft-versus-leukemia in allogenic HSCT.
Sat Feb 15 00:00:00 EST 2014
Oxidized lipids block antigen cross-presentation by dendritic cells in cancer.
Journal of immunology (Baltimore, Md. : 1950)
Ramakrishnan R,Tyurin VA,Veglia F,Condamine T,Amoscato A,Mohammadyani D,Johnson JJ,Zhang LM,Klein-Seetharaman J,Celis E,Kagan VE,Gabrilovich DI
17-5321 was used in Flow cytometry/Cell sorting to reveal a novel role for oxidised lipids in the regulation of cross-presentation.
Sat Mar 15 00:00:00 EDT 2014
Central role of conventional dendritic cells in regulation of bone marrow release and survival of neutrophils.
Journal of immunology (Baltimore, Md. : 1950)
Jiao J,Dragomir AC,Kocabayoglu P,Rahman AH,Chow A,Hashimoto D,Leboeuf M,Kraus T,Moran T,Carrasco-Avino G,Friedman SL,Merad M,Aloman C
17-5321 was used in Flow cytometry/Cell sorting to investigate the role of dendritic cells in neutrophil homeostasis, showing a central role in regulation of bone marrow release and survival of neutrophils.
Tue Apr 01 00:00:00 EDT 2014
Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge.
Human vaccines & immunotherapeutics
Wang S,Wu B,Xue J,Wang M,Chen R,Wang B
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Mon Jan 05 00:00:00 EST 2015
BCG vaccine mediated reduction in the MHC-II expression of macrophages and dendritic cells is reversed by activation of Toll-like receptors 7 and 9.
Cellular immunology
Bakhru P,Sirisaengtaksin N,Soudani E,Mukherjee S,Khan A,Jagannath C
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2014
Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.
PloS one
Xiao GY,Liu IH,Cheng CC,Chang CC,Lee YH,Cheng WT,Wu SC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Thu May 28 00:00:00 EDT 2015
Assessing the role of STAT3 in DC differentiation and autologous DC immunotherapy in mouse models of GBM.
PloS one
Assi H,Espinosa J,Suprise S,Sofroniew M,Doherty R,Zamler D,Lowenstein PR,Castro MG
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Fri Jan 23 00:00:00 EST 2015
Recovery of extracellular vesicles from human breast milk is influenced by sample collection and vesicle isolation procedures.
Journal of extracellular vesicles
Zonneveld MI,Brisson AR,van Herwijnen MJ,Tan S,van de Lest CH,Redegeld FA,Garssen J,Wauben MH,Nolte-'t Hoen EN
17-5321 was used in Flow cytometry/Cell sorting to define parameters important for EV recovery from fresh and stored breast milk.
Wed Sep 10 00:00:00 EDT 2014
Medullary thymic epithelial cell depletion leads to autoimmune hepatitis.
The Journal of clinical investigation
Bonito AJ,Aloman C,Fiel MI,Danzl NM,Cha S,Weinstein EG,Jeong S,Choi Y,Walsh MC,Alexandropoulos K
17-5321 was used in Flow cytometry/Cell sorting to investigate the role of TRAF6 and medullary thymic epithelial cells (mETCs) in autoimmunity, showing that mETC depletion leads to autoimmune hepatitis.
Thu Aug 01 00:00:00 EDT 2013
Efficiently stimulated adult microglia cross-prime naive CD8+ T cells injected in the brain.
European journal of immunology
Jarry U,Jeannin P,Pineau L,Donnou S,Delneste Y,Couez D
17-5321 was used in Flow cytometry/Cell sorting to study whether microglia are able to cross-present antigen to naive CD8(+) T cells within the brain microenvironment in vivo.
Wed May 01 00:00:00 EDT 2013
Characterization of cardiac-resident progenitor cells expressing high aldehyde dehydrogenase activity.
BioMed research international
Roehrich ME,Spicher A,Milano G,Vassalli G
17-5321 was used in Flow cytometry/Cell sorting to investigate the presence of cardiac-resident progenitor cells with high aldehyde dehydrogenase activity isolated from mouse hearts.
Tue Sep 03 00:00:00 EDT 2013
Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages.
Blood
He H,Xu J,Warren CM,Duan D,Li X,Wu L,Iruela-Arispe ML
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Thu Oct 11 00:00:00 EDT 2012
Cross-circulation and cell distribution kinetics in parabiotic mice.
Journal of cellular physiology
Gibney BC,Chamoto K,Lee GS,Simpson DC,Miele LF,Tsuda A,Konerding MA,Wagers A,Mentzer SJ
17-5321 was used in Flow cytometry/Cell sorting to conclude that parabiosis can provide important insights into defining tissue distribution, residence times, and recirculating pools.
Wed Feb 01 00:00:00 EST 2012
Myeloid-derived suppressor cells from tumor-bearing mice impair TGF-β-induced differentiation of CD4+CD25+FoxP3+ Tregs from CD4+CD25-FoxP3- T cells.
Journal of leukocyte biology
Centuori SM,Trad M,LaCasse CJ,Alizadeh D,Larmonier CB,Hanke NT,Kartchner J,Janikashvili N,Bonnotte B,Larmonier N,Katsanis E
17-5321 was used in Flow cytometry/Cell sorting to indicate that gr-MDSCs from TB hosts have the unanticipated ability to restrict immunosuppressive Tregs.
Thu Nov 01 00:00:00 EDT 2012
Staphylococcus aureus induces type I IFN signaling in dendritic cells via TLR9.
Journal of immunology (Baltimore, Md. : 1950)
Parker D,Prince A
17-5321 was used in Flow cytometry/Cell sorting to illustrate an additional mechanism through which S. aureus exploits innate immune signalling to facilitate infection.
Mon Oct 15 00:00:00 EDT 2012
OX40 ligand and programmed cell death 1 ligand 2 expression on inflammatory dendritic cells regulates CD4 T cell cytokine production in the lung during viral disease.
Journal of immunology (Baltimore, Md. : 1950)
Wythe SE,Dodd JS,Openshaw PJ,Schwarze J
17-5321 was used in Flow cytometry/Cell sorting to study the regulation of CD4 T cell cytokine release during viral lung disease, by OX40 and PD-L2 expression on inflammatory dendritic cells.
Wed Feb 15 00:00:00 EST 2012
Losartan inhibits conventional dendritic cell maturation and Th1 and Th17 polarization responses: Νovel mechanisms of preventive effects on lipopolysaccharide-induced acute lung injury.
International journal of molecular medicine
Liu J,Zhang PS,Yu Q,Liu L,Yang Y,Guo FM,Qiu HB
17-5321 was used in Flow cytometry/Cell sorting to demonstrate that losartan suppresses conventional dendritic cell maturation and Th1 and Th17 polarization responses.
Wed Feb 01 00:00:00 EST 2012
Depletion of macrophages and dendritic cells in ischemic acute kidney injury.
American journal of nephrology
Lu L,Faubel S,He Z,Andres Hernando A,Jani A,Kedl R,Edelstein CL
17-5321 was used in Flow cytometry/Cell sorting to demonstrate that macrophage and dendritic cell depletion is protective against ischemic acute kidney injury.
Fri Jun 15 00:00:00 EDT 2012
CD36 modulates proinflammatory cytokine responses to Plasmodium falciparum glycosylphosphatidylinositols and merozoites by dendritic cells.
Parasite immunology
Kumar S,Gowda NM,Wu X,Gowda RN,Gowda DC
17-5321 was used in Flow cytometry/Cell sorting to demonstrate that CD36 modulates the activity of Plasmodium falciparum merozoites.
Sun Jul 01 00:00:00 EDT 2012
Isolation and characterization of novel murine epiphysis derived mesenchymal stem cells.
PloS one
Cheng CC,Lian WS,Hsiao FS,Liu IH,Lin SP,Lee YH,Chang CC,Xiao GY,Huang HY,Cheng CF,Cheng WT,Wu SC
Published figure using MHC Class II (I-A/I-E) monoclonal antibody (Product # 17-5321-82) in Flow Cytometry
Fri Sep 07 00:00:00 EDT 2012
Impact of enzymatic tissue disintegration on the level of surface molecule expression and immune cell function.
European journal of microbiology & immunology
Autengruber A,Gereke M,Hansen G,Hennig C,Bruder D
17-5321 was used in Flow cytometry/Cell sorting to indicate that enzymatic tissue disintegration can have profound effects on the expression of a variety of cell-surface molecules.
Fri Jun 01 00:00:00 EDT 2012
Fluorescent labeling of nano-sized vesicles released by cells and subsequent quantitative and qualitative analysis by high-resolution flow cytometry.
Nature protocols
van der Vlist EJ,Nolte-'t Hoen EN,Stoorvogel W,Arkesteijn GJ,Wauben MH
17-5321-82 was used in Flow cytometry/Cell sorting to provide a protocol for a high-resolution flow cytometry-based method for quantitative and qualitative analysis of individual nano-sized vesicles released by cells.
Thu Jun 14 00:00:00 EDT 2012
Transmembrane mutations in Toll-like receptor 9 bypass the requirement for ectodomain proteolysis and induce fatal inflammation.
Immunity
Mouchess ML,Arpaia N,Souza G,Barbalat R,Ewald SE,Lau L,Barton GM
17-5321 was used in Flow cytometry/Cell sorting to elucidate residues within the TLR9 transmembrane region that confer the requirement for ectodomain proteolysis.
Wed Nov 23 00:00:00 EST 2011
Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths.
Immunity
Ohnmacht C,Schwartz C,Panzer M,Schiedewitz I,Naumann R,Voehringer D
17-5321 was used in Flow cytometry/Cell sorting to demonstrate that basophils play an important role for protective immunity against helminths and orchestrate chronic allergic inflammation.
Fri Sep 24 00:00:00 EDT 2010
Alternatively activated macrophages inhibit T-cell proliferation by Stat6-dependent expression of PD-L2.
Blood
Huber S,Hoffmann R,Muskens F,Voehringer D
17-5321 was used in Flow cytometry/Cell sorting to study how IL-4 induced the expression of PD-L2 on CAM, and LPS increased the expression of PD-L1 on alternatively activated macrophages.
Thu Oct 28 00:00:00 EDT 2010
8-methoxypsoralen plus ultraviolet A therapy acts via inhibition of the IL-23/Th17 axis and induction of Foxp3+ regulatory T cells involving CTLA4 signaling in a psoriasis-like skin disorder.
Journal of immunology (Baltimore, Md. : 1950)
Singh TP,Schön MP,Wallbrecht K,Michaelis K,Rinner B,Mayer G,Schmidbauer U,Strohmaier H,Wang XJ,Wolf P
17-5321 was used in Flow cytometry/Cell sorting to elucidate the mechanism of PUVA for treatment of psoriasis, showing that inhibition of the IL-23/Th17 axis and induction of Foxp3+ regulatory T cells involves CTLA4 signalling.
Tue Jun 15 00:00:00 EDT 2010
Dendritic cells continue to capture and present antigens after maturation in vivo.
Journal of immunology (Baltimore, Md. : 1950)
Drutman SB,Trombetta ES
17-5321 was used in Flow cytometry/Cell sorting to study the dynamics of Ag capture and presentation in situ, showing that dendritic cells continue to capture and present antigens after maturation.
Sun Aug 15 00:00:00 EDT 2010
Dysregulated macrophage-inflammatory protein-2 expression drives illness in bacterial superinfection of influenza.
Journal of immunology (Baltimore, Md. : 1950)
Zavitz CC,Bauer CM,Gaschler GJ,Fraser KM,Strieter RM,Hogaboam CM,Stampfli MR
17-5321 was used in Flow cytometry/Cell sorting to suggest that pulmonary inflammation is the key threat during bacterial superinfection of influenza.
Mon Feb 15 00:00:00 EST 2010
Antigen-specific immunity and cross-priming by epithelial ovarian carcinoma-induced CD11b(+)Gr-1(+) cells.
Journal of immunology (Baltimore, Md. : 1950)
Tomihara K,Guo M,Shin T,Sun X,Ludwig SM,Brumlik MJ,Zhang B,Curiel TJ,Shin T
17-5321 was used in Flow cytometry/Cell sorting to investigate CD11b(+)Gr-1(+) cells found in epithelial ovarian cancer-bearing mice, which are induced by ovarian cancer cells and undergo antigen-specific immunity and cross-priming.
Tue Jun 01 00:00:00 EDT 2010
CD4 T-cell suppression by cells from Toxoplasma gondii-infected retinas is mediated by surface protein PD-L1.
Infection and immunity
Charles E,Joshi S,Ash JD,Fox BA,Farris AD,Bzik DJ,Lang ML,Blader IJ
17-5321 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which the retina protects itself from CD4 T-cell-mediated immune damage in retinal immune responses.
Sun Aug 01 00:00:00 EDT 2010
DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration.
PloS one
Osada M,Jardine L,Misir R,Andl T,Millar SE,Pezzano M
17-5321 was used in Flow cytometry/Cell sorting to demonstrate that canonical Wnt signaling within TECs is required for the maintenance of epithelial microenvironments in the postnatal thymus.
Mon Feb 08 00:00:00 EST 2010
A method for generation of bone marrow-derived macrophages from cryopreserved mouse bone marrow cells.
PloS one
Marim FM,Silveira TN,Lima DS,Zamboni DS
17-5321 was used in Flow cytometry/Cell sorting to present a method for the easy generation of bone marrow-derived macrophages from frozen bone marrow cells.
Fri Dec 17 00:00:00 EST 2010
Mycobacterium bovis BCG decreases MHC-II expression in vivo on murine lung macrophages and dendritic cells during aerosol infection.
Cellular immunology
Pecora ND,Fulton SA,Reba SM,Drage MG,Simmons DP,Urankar-Nagy NJ,Boom WH,Harding CV
17-5321 was used in Flow cytometry/Cell sorting to show lung APCs that harbour mycobacteria in vivo have decreased MHC-II expression relative to uninfected APCs from the same lung.
Fri Jan 02 00:00:00 EST 2009
Polymeric linear Peptide chimeric vaccine-induced antimalaria immunity is associated with enhanced in vitro antigen loading.
Infection and immunity
Silva-Flannery LM,Cabrera-Mora M,Dickherber M,Moreno A
17-5321 was used in Flow cytometry/Cell sorting to investigate the antigenic properties of polymeric antimalarial peptides, showing that immunity is associated with enhanced in vitro antigen loading.
Fri May 01 00:00:00 EDT 2009
Stratification of Antigen-presenting Cells within the Normal Cornea.
Ophthalmology and eye diseases
Knickelbein JE,Watkins SC,McMenamin PG,Hendricks RL
17-5321 was used in Immunofluorescence on wholemounted tissues to investigate the presence of antigen-presenting cells within the non-inflamed cornea.
Wed Nov 25 00:00:00 EST 2009
Nitric oxide is a key component in inflammation-accelerated tumorigenesis.
Cancer research
Hussain SP,He P,Subleski J,Hofseth LJ,Trivers GE,Mechanic L,Hofseth AB,Bernard M,Schwank J,Nguyen G,Mathe E,Djurickovic D,Haines D,Weiss J,Back T,Gruys E,Laubach VE,Wiltrout RH,Harris CC
17-5321 was used in Flow cytometry/Cell sorting to test the hypothesis that an inflammatory microenvironment with an enhanced level of nitric oxide accelerates spontaneous tumour development (tumorigenesis).
Mon Sep 01 00:00:00 EDT 2008
CD24a expression levels discriminate Langerhans cells from dermal dendritic cells in murine skin and lymph nodes.
The Journal of investigative dermatology
Stutte S,Jux B,Esser C,Förster I
17-5321 was used in Flow cytometry/Cell sorting to investigate a novel method to distinguish LCs from dDCs.
Sun Jun 01 00:00:00 EDT 2008
The surprising kinetics of the T cell response to live antigenic cells.
Journal of immunology (Baltimore, Md. : 1950)
Tyznik AJ,Bevan MJ
17-5321 was used in Flow cytometry/Cell sorting to demonstrate dramatic differences in host T cell responses to noninflammatory Ags compared with responses to pathogens.
Mon Oct 15 00:00:00 EDT 2007
