Product References
NLRP12-expressing dendritic cells mediate both dissemination of infection and adaptive immune responses in visceral leishmaniasis.
iScience
Valadares DG,Clay OS,Chen Y,Scorza BM,Cassel SL,Sutterwala FS,Wilson ME
11-0454-82 was used in Flow Cytometry to hypothesize that Nlrp12-expressing DCs are required for efficient dissemination and immune clearance of L. infantum from the site of initial infection.
Fri Mar 17 00:00:00 EDT 2023
A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts.
Immunity
Zindl CL,Witte SJ,Laufer VA,Gao M,Yue Z,Janowski KM,Cai B,Frey BF,Silberger DJ,Harbour SN,Singer JR,Turner H,Lund FE,Vallance BA,Rosenberg AF,Schoeb TR,Chen JY,Hatton RD,Weaver CT
11-0454-82 was used in Flow cytometry/Cell sorting to demonstrate spatiotemporal differences in the production and action of IL-22 by ILCs and T cells during infection and reveal an indispensable role for IL-22-producing T cells in the protection of the intestinal crypts.
Tue Mar 08 00:00:00 EST 2022
Primary germinal center-resident T follicular helper cells are a physiologically distinct subset of CXCR5hiPD-1hi T follicular helper cells.
Immunity
Yeh CH,Finney J,Okada T,Kurosaki T,Kelsoe G
11-0454-82 was used in Flow cytometry/Cell sorting to examine whether GC-resident and -nonresident Tfh cells share a common physiology and function.
Tue Feb 08 00:00:00 EST 2022
Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation.
Nature immunology
Rivas MA,Meydan C,Chin CR,Challman MF,Kim D,Bhinder B,Kloetgen A,Viny AD,Teater MR,McNally DR,Doane AS,Béguelin W,Fernández MTC,Shen H,Wang X,Levine RL,Chen Z,Tsirigos A,Elemento O,Mason CE,Melnick AM
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Niche-specific MHC II and PD-L1 regulate CD4+CD8αα+ intraepithelial lymphocyte differentiation.
The Journal of experimental medicine
Moon S,Park Y,Hyeon S,Kim YM,Kim JH,Kim H,Park S,Lee KJ,Koo BK,Ha SJ,Lee SW
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Mon Apr 05 00:00:00 EDT 2021
Aggravation of hepatic ischemia‑reperfusion injury with increased inflammatory cell infiltration is associated with the TGF‑β/Smad3 signaling pathway.
Molecular medicine reports
Li H,Shen X,Tong Y,Ji T,Feng Y,Tang Y,Mai R,Ye J,Que T,Luo X
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Immunohistochemistry
Sun Aug 01 00:00:00 EDT 2021
Brd4 modulates diet-induced obesity via PPARγ-dependent Gdf3 expression in adipose tissue macrophages.
JCI insight
Hu X,Dong X,Li G,Chen Y,Chen J,He X,Sun H,Kim DH,Kemper JK,Chen LF
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Thu Apr 08 00:00:00 EDT 2021
Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling.
Cell reports
Young IC,Wu B,Andricovich J,Chuang ST,Li R,Tzatsos A,Wu RC,Wu MY
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Tue Nov 23 00:00:00 EST 2021
Erythritol Ameliorates Small Intestinal Inflammation Induced by High-Fat Diets and Improves Glucose Tolerance.
International journal of molecular sciences
Kawano R,Okamura T,Hashimoto Y,Majima S,Senmaru T,Ushigome E,Asano M,Yamazaki M,Takakuwa H,Sasano R,Nakanishi N,Hamaguchi M,Fukui M
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Mon May 24 00:00:00 EDT 2021
Expansion of an Unusual Virtual Memory CD8+ Subpopulation Bearing Vα3.2 TCR in Themis-Deficient Mice.
Frontiers in immunology
Prasad M,Wojciech L,Brzostek J,Hu J,Chua YL,Tung DWH,Yap J,Rybakin V,Gascoigne NRJ
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Thu Sep 23 00:00:00 EDT 2021
The subunits of IL-12, originating from two distinct cells, can functionally synergize to protect against pathogen dissemination in vivo.
Cell reports
Gerber AN,Abdi K,Singh NJ
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Intestinal CD11b+ B Cells Ameliorate Colitis by Secreting Immunoglobulin A.
Frontiers in immunology
Fu Y,Wang Z,Yu B,Lin Y,Huang E,Liu R,Zhao C,Lu M,Xu W,Liu H,Liu Y,Wang L,Chu Y
11-0454-82 was used in Flow Cytometry to demonstrate that CD11b+ B cells are essential intestinal suppressive immune cells and the primary source of intestinal IgA, which plays an indispensable role in maintaining intestinal homeostasis.
Fri Jan 07 00:00:00 EST 2022
Ddb1 Is Essential for the Expansion of CD4+ Helper T Cells by Regulating Cell Cycle Progression and Cell Death.
Frontiers in immunology
Yang L,Chen W,Li L,Xiao Y,Fan S,Zhang Q,Xia T,Li M,Hong Y,Zhao T,Li Q,Liu WH,Xiao N
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Mon Dec 20 00:00:00 EST 2021
Abraxane-induced bone marrow CD11b+ myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with 64Cu-labeled anti-CD11b and prevented by anti-CSF-1.
Theranostics
Cao Q,Huang Q,Wang YA,Li C
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Fri Jul 23 00:00:00 EDT 2021
Abraxane-induced bone marrow CD11b+ myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with 64Cu-labeled anti-CD11b and prevented by anti-CSF-1.
Theranostics
Cao Q,Huang Q,Wang YA,Li C
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Fri Jul 23 00:00:00 EDT 2021
Influenza virus infection expands the breadth of antibody responses through IL-4 signalling in B cells.
Nature communications
Miyauchi K,Adachi Y,Tonouchi K,Yajima T,Harada Y,Fukuyama H,Deno S,Iwakura Y,Yoshimura A,Hasegawa H,Yugi K,Fujii SI,Ohara O,Takahashi Y,Kubo M
11-0454-82 was used in Flow Cytometry to show that nasal infection controls two sequential processes to induce neutralizing IgG antibodies recognizing the hemagglutinin (HA) of heterotypic strains.
Fri Jun 18 00:00:00 EDT 2021
TNF-α-induced alterations in stromal progenitors enhance leukemic stem cell growth via CXCR2 signaling.
Cell reports
Agarwal P,Li H,Choi K,Hueneman K,He J,Welner RS,Starczynowski DT,Bhatia R
11-0454-82 was used in Flow Cytometry to find that TNF-α-mediated alterations in CML BM stromal niches enhance support of LSC maintenance and growth via CXCL1-CXCR2 signaling and that CXCR2 inhibition effectively depletes CML LSCs.
Tue Jul 13 00:00:00 EDT 2021
The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition.
Cell reports
Azzoni E,Frontera V,Anselmi G,Rode C,James C,Deltcheva EM,Demian AS,Brown J,Barone C,Patelli A,Harman JR,Nicholls M,Conway SJ,Morrissey E,Jacobsen SEW,Sparrow DB,Harris AL,Enver T,de Bruijn MFTR
11-0454-82 was used in Immunocytochemistry-immunoflourescence to investigate how and when the onset of circulation affects Hematopoietic stem cells emergence.
Tue Dec 14 00:00:00 EST 2021
Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy.
Cell
Wu L,Hollinshead KER,Hao Y,Au C,Kroehling L,Ng C,Lin WY,Li D,Silva HM,Shin J,Lafaille JJ,Possemato R,Pacold ME,Papagiannakopoulos T,Kimmelman AC,Satija R,Littman DR
11-0454-82 was used in Flow Cytometry to suggest that inhibiting glycolysis by targeting Gpi1 could be an effective therapeutic strategy with minimum toxicity for Th17-mediated autoimmune diseases, and, more generally, that metabolic redundancies can be exploited for selective targeting of disease processes.
Thu Aug 06 00:00:00 EDT 2020
m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development.
Immunity
Gao Y,Vasic R,Song Y,Teng R,Liu C,Gbyli R,Biancon G,Nelakanti R,Lobben K,Kudo E,Liu W,Ardasheva A,Fu X,Wang X,Joshi P,Lee V,Dura B,Viero G,Iwasaki A,Fan R,Xiao A,Flavell RA,Li HB,Tebaldi T,Halene S
11-0454-82 was used in Flow Cytometry to investigate if N6-methyladenosine modification protects against endogenous double-stranded RNAs formation and a deleterious innate immune response during mammalian hematopoietic development.
Tue Jun 16 00:00:00 EDT 2020
Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy.
Immunity
Milner JJ,Toma C,He Z,Kurd NS,Nguyen QP,McDonald B,Quezada L,Widjaja CE,Witherden DA,Crowl JT,Shaw LA,Yeo GW,Chang JT,Omilusik KD,Goldrath AW
11-0454 was used in Flow cytometry/Cell sorting to identify discrete lineages of intestinal antigen-specific CD8+ T cells, including a Blimp1hiId3lo tissue-resident effector cell population most prominent in the early phase of acute viral and bacterial infections and a molecularly distinct Blimp1loId3hi tissue-resident memory population that subsequently accumulated at later infection time points.
Tue May 19 00:00:00 EDT 2020
Antibody Feedback Limits the Expansion of B Cell Responses to Malaria Vaccination but Drives Diversification of the Humoral Response.
Cell host & microbe
McNamara HA,Idris AH,Sutton HJ,Vistein R,Flynn BJ,Cai Y,Wiehe K,Lyke KE,Chatterjee D,Kc N,Chakravarty S,Lee Sim BK,Hoffman SL,Bonsignori M,Seder RA,Cockburn IA
11-0454 was used in Flow cytometry/Cell sorting to suggest that antibody feedback drives the diversification of immune responses and that vaccination for malaria will require targeting multiple antigens.
Wed Oct 07 00:00:00 EDT 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
11-0454 was used in Flow cytometry/Cell sorting to uncover a mechanism that controls myeloid regeneration and early lineage decisions in HSCs and could be targeted in LSCs to normalize leukemic myeloid cell production.
Mon Mar 02 00:00:00 EST 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
11-0454 was used in Flow cytometry/Cell sorting to uncover a mechanism that controls myeloid regeneration and early lineage decisions in HSCs and could be targeted in LSCs to normalize leukemic myeloid cell production.
Mon Mar 02 00:00:00 EST 2020
Proenkephalin+ regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function.
Proceedings of the National Academy of Sciences of the United States of America
Shime H,Odanaka M,Tsuiji M,Matoba T,Imai M,Yasumizu Y,Uraki R,Minohara K,Watanabe M,Bonito AJ,Fukuyama H,Ohkura N,Sakaguchi S,Morita A,Yamazaki S
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Tue Aug 25 00:00:00 EDT 2020
Nanoparticle-Coupled Topical Methotrexate Can Normalize Immune Responses and Induce Tissue Remodeling in Psoriasis.
The Journal of investigative dermatology
Özcan A,Sahin D,Impellizzieri D,Nguyen TT,Hafner J,Yawalkar N,Kurzbach D,Tan G,Akdis CA,Nilsson J,Boyman O,Kolios AGA
11-0454 was used in Flow cytometry/Cell sorting to show that MTX coupled with gold nanoparticles (GNPs) demonstrates superior antiinflammatory efficacy than MTX alone in an imiquimod-induced mouse model, significantly reducing γδ T cells, CD4+ T cells, and neutrophils.
Fri May 01 00:00:00 EDT 2020
Sema3A and HIF1α co-overexpressed iPSC-MSCs/HA scaffold facilitates the repair of calvarial defect in a mouse model.
Journal of cellular physiology
Li J,Wang T,Li C,Wang Z,Wang P,Zheng L
11-0454-82 was used in Flow cytometry/Cell sorting to show that Sema3A and HIF1α co-overexpression reversed the reduced cell proliferation that reduced by Sema3A overexpression alone.
Thu Oct 01 00:00:00 EDT 2020
Osteoclasts Derive Predominantly from Bone Marrow-Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair.
Journal of immunology (Baltimore, Md. : 1950)
Novak S,Roeder E,Kalinowski J,Jastrzebski S,Aguila HL,Lee SK,Kalajzic I,Lorenzo JA
11-0454 was used in Flow cytometry/Cell sorting to demonstrate that OCP, but not mature OC, express CX3CR1 during both homeostasis and fracture repair.
Sat Feb 15 00:00:00 EST 2020
TGF-β-driven downregulation of the transcription factor TCF7L2 affects Wnt/β-catenin signaling in PDGFRα+ fibroblasts.
Journal of cell science
Contreras O,Soliman H,Theret M,Rossi FMV,Brandan E
11-0454 was used in Flow cytometry/Cell sorting to show that TGF-β requires histone deacetylase activity to repress the expression of TCF7L2.
Fri Jun 19 00:00:00 EDT 2020
Interleukin 35 Delays Hindlimb Ischemia-Induced Angiogenesis Through Regulating ROS-Extracellular Matrix but Spares Later Regenerative Angiogenesis.
Frontiers in immunology
Fu H,Sun Y,Shao Y,Saredy J,Cueto R,Liu L,Drummer C,Johnson C,Xu K,Lu Y,Li X,Meng S,Xue ER,Tan J,Jhala NC,Yu D,Zhou Y,Bayless KJ,Yu J,Rogers TJ,Hu W,Snyder NW,Sun J,Qin X,Jiang X,Wang H,Yang X
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Fri Jul 09 00:00:00 EDT 2021
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
11-0454-81 was used in Flow Cytometry to show that disruption of the Gdpd3 gene encoding a lysophospholipase D enzyme decreases the self-renewal capacity of murine chronic myelogenous leukaemia stem cells.
Thu Sep 17 00:00:00 EDT 2020
Microglial A20 Protects the Brain from CD8 T-Cell-Mediated Immunopathology.
Cell reports
Mohebiany AN,Ramphal NS,Karram K,Di Liberto G,Novkovic T,Klein M,Marini F,Kreutzfeldt M,Härtner F,Lacher SM,Bopp T,Mittmann T,Merkler D,Waisman A
11-0454 was used in Flow cytometry/Cell sorting to investigate the role of tumor-necrosis-factor-alpha-induced protein 3 in the central nervous system (CNS).
Tue Feb 04 00:00:00 EST 2020
Continued Bcl6 Expression Prevents the Transdifferentiation of Established Tfh Cells into Th1 Cells during Acute Viral Infection.
Cell reports
Alterauge D,Bagnoli JW,Dahlström F,Bradford BM,Mabbott NA,Buch T,Enard W,Baumjohann D
11-0454-82 was used in Flow Cytometry to evaluate the contributions of the CXCR5 receptor and Bcl6 transcription factor in maintaining T follicular helper cells and germinal centres.
Tue Oct 06 00:00:00 EDT 2020
The frequency of follicular T helper cells differs in acute and chronic neuroinflammation.
Scientific reports
Baniahmad A,Birkner K,Görg J,Loos J,Zipp F,Wasser B,Bittner S
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Tue Nov 24 00:00:00 EST 2020
Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities.
Nature communications
Cho SX,Rudloff I,Lao JC,Pang MA,Goldberg R,Bui CB,McLean CA,Stock M,Klassert TE,Slevogt H,Mangan NE,Cheng W,Fischer D,Gfroerer S,Sandhu MK,Ngo D,Bujotzek A,Lariviere L,Schumacher F,Tiefenthaler G,Beker F,Collins C,Kamlin COF,König K,Malhotra A,Tan K,Theda C,Veldman A,Ellisdon AM,Whisstock JC,Berger PJ,Nold-Petry CA,Nold MF
11-0454 was used in Flow cytometry/Cell sorting to implicate type 3 cytokines, TLRs and IL-37 as potential targets for novel Necrotizing enterocolitis therapies.
Fri Nov 13 00:00:00 EST 2020
Pathogenic Potential of Hic1-Expressing Cardiac Stromal Progenitors.
Cell stem cell
Soliman H,Paylor B,Scott RW,Lemos DR,Chang C,Arostegui M,Low M,Lee C,Fiore D,Braghetta P,Pospichalova V,Barkauskas CE,Korinek V,Rampazzo A,MacLeod K,Underhill TM,Rossi FMV
11-0454 was used in Flow cytometry/Cell sorting to identifyheart-resident PDGFRa+ SCA-1+ cells as cardiac fibro/adipogenic progenitors (cFAPs) and show that they respond to ischemic damage by generating fibrogenic cells.
Thu Feb 06 00:00:00 EST 2020
Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation.
Nature
Wilkinson AC,Ishida R,Kikuchi M,Sudo K,Morita M,Crisostomo RV,Yamamoto R,Loh KM,Nakamura Y,Watanabe M,Nakauchi H,Yamazaki S
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Mon Jul 01 00:00:00 EDT 2019
The cis-Regulatory Atlas of the Mouse Immune System.
Cell
Yoshida H,Lareau CA,Ramirez RN,Rose SA,Maier B,Wroblewska A,Desland F,Chudnovskiy A,Mortha A,Dominguez C,Tellier J,Kim E,Dwyer D,Shinton S,Nabekura T,Qi Y,Yu B,Robinette M,Kim KW,Wagers A,Rhoads A,Nutt SL,Brown BD,Mostafavi S,Buenrostro JD,Benoist C
11-0454-82 was used in Flow Cytometry to generate matched epigenome and transcriptome measurements in 86 primary cell types that span the mouse immune system and its differentiation cascade.
Thu Feb 07 00:00:00 EST 2019
A Subset of Type I Conventional Dendritic Cells Controls Cutaneous Bacterial Infections through VEGFα-Mediated Recruitment of Neutrophils.
Immunity
Janela B,Patel AA,Lau MC,Goh CC,Msallam R,Kong WT,Fehlings M,Hubert S,Lum J,Simoni Y,Malleret B,Zolezzi F,Chen J,Poidinger M,Satpathy AT,Briseno C,Wohn C,Malissen B,Murphy KM,Maini AA,Vanhoutte L,Guilliams M,Vial E,Hennequin L,Newell E,Ng LG,Musette P,Yona S,Hacini-Rachinel F,Ginhoux F
11-0454 was used in Flow cytometry/Cell sorting to show that skin cDC1s are essential regulators of the innate response in cutaneous immunity and have roles beyond classical antigen presentation.
Tue Apr 16 00:00:00 EDT 2019
Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis.
Cell metabolism
Camell CD,Günther P,Lee A,Goldberg EL,Spadaro O,Youm YH,Bartke A,Hubbard GB,Ikeno Y,Ruddle NH,Schultze J,Dixit VD
11-0454 was used in Flow cytometry/Cell sorting to study the role of ageing within alterations of adipose tissue.
Tue Dec 03 00:00:00 EST 2019
Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells.
Cell stem cell
Agarwal P,Isringhausen S,Li H,Paterson AJ,He J,Gomariz Á,Nagasawa T,Nombela-Arrieta C,Bhatia R
11-0454-82 was used in Flow Cytometry to highlight a critical role of niche-specific effects of Cxcl12 expression in maintaining quiescence of TKI-resistant LSC populations.
Thu May 02 00:00:00 EDT 2019
TNF-α Coordinates Hematopoietic Stem Cell Survival and Myeloid Regeneration.
Cell stem cell
Yamashita M,Passegué E
11-0454 was used in Flow cytometry/Cell sorting to reveal several TNF-α-mediated pro-survival mechanisms unique to HSCs, highlight an important role for necroptosis in HSC killing, and establish TNF-α as a major pro-survival and pro-regeneration factor for HSCs.
Thu Sep 05 00:00:00 EDT 2019
SIRT1 regulates metabolism and leukemogenic potential in CML stem cells.
The Journal of clinical investigation
Abraham A,Qiu S,Chacko BK,Li H,Paterson A,He J,Agarwal P,Shah M,Welner R,Darley-Usmar VM,Bhatia R
11-0454 was used in Flow cytometry/Cell sorting to demonstrate an important role for SIRT1 in leukemia development.
Mon Jun 10 00:00:00 EDT 2019
Formyl peptide receptor 2 regulates monocyte recruitment to promote intestinal mucosal wound repair.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Birkl D,O'Leary MN,Quiros M,Azcutia V,Schaller M,Reed M,Nishio H,Keeney J,Neish AS,Lukacs NW,Parkos CA,Nusrat A
11-0454-82 was used in Flow Cytometry to study how Fpr2/3 regulates CCL20-CCR6-mediated monocyte chemotaxis to sites of mucosal injury in the gut to influence wound repair.
Sun Dec 01 00:00:00 EST 2019
Cross-talk between TGF-β and PDGFRα signaling pathways regulates the fate of stromal fibro-adipogenic progenitors.
Journal of cell science
Contreras O,Cruz-Soca M,Theret M,Soliman H,Tung LW,Groppa E,Rossi FM,Brandan E
11-0454 was used in Flow cytometry/Cell sorting to investigate the role of functional cross-talk between TGF-β and PDGFRα signaling pathways in the fate of fibro-adipogenic progenitors (FAPs).
Wed Oct 09 00:00:00 EDT 2019
Direct CD137 costimulation of CD8 T cells promotes retention and innate-like function within nascent atherogenic foci.
American journal of physiology. Heart and circulatory physiology
Xu MM,Ménoret A,Nicholas SE,Günther S,Sundberg EJ,Zhou B,Rodriguez A,Murphy PA,Vella AT
11-0454 was used in Flow cytometry/Cell sorting to provide novel insight into CD137 costimulation of effector T cells, independent of plaque-antigen recognition, instigates their retention and promotes innate-like responses from immune infiltrates within atherogenic foci.
Sat Jun 01 00:00:00 EDT 2019
Interleukin-22 (IL-22) Binding Protein Constrains IL-22 Activity, Host Defense, and Oxidative Phosphorylation Genes during Pneumococcal Pneumonia.
Infection and immunity
Trevejo-Nunez G,Elsegeiny W,Aggor FEY,Tweedle JL,Kaplan Z,Gandhi P,Castillo P,Ferguson A,Alcorn JF,Chen K,Kolls JK,Gaffen SL
11-0454 was used in Flow cytometry/Cell sorting to demonstrate the role of IL-22BP as a natural inhibitor of IL-22 in the lung.
Fri Nov 01 00:00:00 EDT 2019
Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging.
Cell reports
Luo H,Mu WC,Karki R,Chiang HH,Mohrin M,Shin JJ,Ohkubo R,Ito K,Kanneganti TD,Chen D
11-0454-82 was used in Flow Cytometry to assess whether the NLRP3 inflammasome is aberrantly activated in haematopoietic stem cells during physiological ageing.
Tue Jan 22 00:00:00 EST 2019
Spatial Genome Re-organization between Fetal and Adult Hematopoietic Stem Cells.
Cell reports
Chen C,Yu W,Tober J,Gao P,He B,Lee K,Trieu T,Blobel GA,Speck NA,Tan K
11-0454 was used in Flow cytometry/Cell sorting to find that chromosomal compartments and topologically associating domains (TADs) are largely conserved between fetal and adult HSCs.
Tue Dec 17 00:00:00 EST 2019
Increased Incidence of Colon Tumors in AOM-Treated Apc 1638N/+ Mice Reveals Higher Frequency of Tumor Associated Neutrophils in Colon Than Small Intestine.
Frontiers in oncology
Metzger R,Maruskova M,Krebs S,Janssen KP,Krug AB
11-0454-82 was used in Immunohistochemistry to characterize tumor infiltrating immune cells in spontaneously developing colon tumors compared to small intestinal tumors.
Thu Oct 01 00:00:00 EDT 2020
N-Cadherin-Expressing Bone and Marrow Stromal Progenitor Cells Maintain Reserve Hematopoietic Stem Cells.
Cell reports
Zhao M,Tao F,Venkatraman A,Li Z,Smith SE,Unruh J,Chen S,Ward C,Qian P,Perry JM,Marshall H,Wang J,He XC,Li L
11-0454 was used in Flow cytometry/Cell sorting to report that N-cad+ cells were functional bone and marrow stromal progenitor cells, giving rise to osteoblasts, adipocytes, and chondrocytes both in vitro and in vivo.
Tue Jan 15 00:00:00 EST 2019
Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia.
Nature medicine
Zhang B,Nguyen LXT,Li L,Zhao D,Kumar B,Wu H,Lin A,Pellicano F,Hopcroft L,Su YL,Copland M,Holyoake TL,Kuo CJ,Bhatia R,Snyder DS,Ali H,Stein AS,Brewer C,Wang H,McDonald T,Swiderski P,Troadec E,Chen CC,Dorrance A,Pullarkat V,Yuan YC,Perrotti D,Carlesso N,Forman SJ,Kortylewski M,Kuo YH,Marcucci G
11-0454 was used in Flow cytometry/Cell sorting to demonstrate how bone marrow endothelial cells supply miR-126 to leukemia stem cells in chronic myelogenous leukemia which modulates their quiescence and self-renewal.
Tue May 01 00:00:00 EDT 2018
The H3K4 methyltransferase Setd1b is essential for hematopoietic stem and progenitor cell homeostasis in mice.
eLife
Schmidt K,Zhang Q,Tasdogan A,Petzold A,Dahl A,Arneth BM,Slany R,Fehling HJ,Kranz A,Stewart AF,Anastassiadis K
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Tue Jun 19 00:00:00 EDT 2018
Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
eLife
Moretti FA,Klapproth S,Ruppert R,Margraf A,Weber J,Pick R,Scheiermann C,Sperandio M,Fässler R,Moser M
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
Elimination of intravascular thrombi prevents early mortality and reduces gliosis in hyper-inflammatory experimental cerebral malaria.
Journal of neuroinflammation
Wilson KD,Ochoa LF,Solomon OD,Pal R,Cardona SM,Carpio VH,Keiser PH,Cardona AE,Vargas G,Stephens R
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Immunofluorescence
Mon Jun 04 00:00:00 EDT 2018
Retinoid-Sensitive Epigenetic Regulation of the Hoxb Cluster Maintains Normal Hematopoiesis and Inhibits Leukemogenesis.
Cell stem cell
Qian P,De Kumar B,He XC,Nolte C,Gogol M,Ahn Y,Chen S,Li Z,Xu H,Perry JM,Hu D,Tao F,Zhao M,Han Y,Hall K,Peak A,Paulson A,Zhao C,Venkatraman A,Box A,Perera A,Haug JS,Parmely T,Li H,Krumlauf R,Li L
11-0454 was used in Flow cytometry/Cell sorting to demonstrate roles for retinoid signaling and the DERARE in maintaining HSCs and preventing leukemogenesis by coordinate regulation of Hoxb genes.
Thu May 03 00:00:00 EDT 2018
Role of Macrophage Socs3 in the Pathogenesis of Aortic Dissection.
Journal of the American Heart Association
Ohno-Urabe S,Aoki H,Nishihara M,Furusho A,Hirakata S,Nishida N,Ito S,Hayashi M,Yasukawa H,Imaizumi T,Akashi H,Tanaka H,Fukumoto Y
11-0454 was used in Flow cytometry/Cell sorting to characterise the pathological and molecular events triggered by aortic stress, which can lead to aortic dissection.
Wed Jan 17 00:00:00 EST 2018
MicroRNA-155 Protects Group 2 Innate Lymphoid Cells From Apoptosis to Promote Type-2 Immunity.
Frontiers in immunology
Knolle MD,Chin SB,Rana BMJ,Englezakis A,Nakagawa R,Fallon PG,Git A,McKenzie ANJ
11-0454 was used in Flow cytometry/Cell sorting to identify a subset of micro-RNAs that are regulated upon group-2 innate lymphoid cells (ILC2) activation, and establish a specific role for miR-155 in regulating ILC2 survival following activation.
Mon Sep 30 00:00:00 EDT 2019
Parabiosis and single-cell RNA sequencing reveal a limited contribution of monocytes to myofibroblasts in kidney fibrosis.
JCI insight
Kramann R,Machado F,Wu H,Kusaba T,Hoeft K,Schneider RK,Humphreys BD
11-0454 was used in Flow cytometry/Cell sorting to examine the relative contribution of proximal tubular epithelium and circulating cells to the myofibroblast pool.
Thu May 03 00:00:00 EDT 2018
Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.
Nature communications
Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS
Fri Jun 22 00:00:00 EDT 2018
Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation.
Nature communications
Li H,Yao Q,Mariscal AG,Wu X,Hülse J,Pedersen E,Helin K,Waisman A,Vinkel C,Thomsen SF,Avgustinova A,Benitah SA,Lovato P,Norsgaard H,Mortensen MS,Veng L,Rozell B,Brakebusch C
11-0454 was used in Flow cytometry/Cell sorting to show that keratinocyte-produced IL-23 is sufficient to cause a chronic skin inflammation with an IL-17 profile in mice.
Thu Apr 12 00:00:00 EDT 2018
CCR7 defines a precursor for murine iNKT cells in thymus and periphery.
eLife
Wang H,Hogquist KA
Mon Aug 13 00:00:00 EDT 2018
Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease.
Nature medicine
Hahm E,Wei C,Fernandez I,Li J,Tardi NJ,Tracy M,Wadhwani S,Cao Y,Peev V,Zloza A,Lusciks J,Hayek SS,O'Connor C,Bitzer M,Gupta V,Sever S,Sykes DB,Scadden DT,Reiser J
11-0454 was used in Flow cytometry/Cell sorting to demonstrate a direct pathogenic role of suPAR as a circulating mediator of kidney disease, such as focal segmental glomerulosclerosis.
Sun Jan 01 00:00:00 EST 2017
Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.
Nature
Hérault A,Binnewies M,Leong S,Calero-Nieto FJ,Zhang SY,Kang YA,Wang X,Pietras EM,Chu SH,Barry-Holson K,Armstrong S,Göttgens B,Passegué E
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Immunofluorescence
Thu Apr 06 00:00:00 EDT 2017
Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring.
Nature
Kim S,Kim H,Yim YS,Ha S,Atarashi K,Tan TG,Longman RS,Honda K,Littman DR,Choi GB,Huh JR
11-0454 was used in Flow cytometry/Cell sorting to suggest that defined gut commensal bacteria with a propensity to induce TH17 cells may increase the risk of neurodevelopmental disorders in the offspring of pregnant mothers undergoing immune system activation owing to infections or autoinflammatory syndromes.
Thu Sep 28 00:00:00 EDT 2017
Autophagy maintains the metabolism and function of young and old stem cells.
Nature
Ho TT,Warr MR,Adelman ER,Lansinger OM,Flach J,Verovskaya EV,Figueroa ME,Passegué E
11-0454 was used in Flow cytometry/Cell sorting to demonstrate an essential function for autophagy in removing activated mitochondria and controlling oxidative metabolism, thereby maintaining HSC stemness and regenerative potential.
Thu Mar 09 00:00:00 EST 2017
Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression.
Immunity
Zhu Y,Herndon JM,Sojka DK,Kim KW,Knolhoff BL,Zuo C,Cullinan DR,Luo J,Bearden AR,Lavine KJ,Yokoyama WM,Hawkins WG,Fields RC,Randolph GJ,DeNardo DG
11-0454 was used in Flow cytometry/Cell sorting to uncover the heterogeneity of TAM origin and functions and could provide therapeutic insight for PDAC treatment.
Tue Aug 15 00:00:00 EDT 2017
Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells.
Immunity
Hayatsu N,Miyao T,Tachibana M,Murakami R,Kimura A,Kato T,Kawakami E,Endo TA,Setoguchi R,Watarai H,Nishikawa T,Yasuda T,Yoshida H,Hori S
11-0454 was used in Flow cytometry/Cell sorting to identify BATF as a regulator of tissue regulatory T cells and suggest that sequence-specific perturbations of Foxp3-DNA interactions can influence specific facets of Treg physiology and the immunopathologies.
Tue Aug 15 00:00:00 EDT 2017
Dichotomous Expression of TNF Superfamily Ligands on Antigen-Presenting Cells Controls Post-priming Anti-viral CD4+ T Cell Immunity.
Immunity
Chang YH,Wang KC,Chu KL,Clouthier DL,Tran AT,Torres Perez MS,Zhou AC,Abdul-Sater AA,Watts TH
11-0454-82 was used in Flow Cytometry to investigate how different subtypes of T cell antigen-presenting cell contribute to determining viral set point and disease outcome.
Tue Nov 21 00:00:00 EST 2017
Sphingosine-1-Phosphate Prevents Egress of Hematopoietic Stem Cells From Liver to Reduce Fibrosis.
Gastroenterology
King A,Houlihan DD,Kavanagh D,Haldar D,Luu N,Owen A,Suresh S,Than NN,Reynolds G,Penny J,Sumption H,Ramachandran P,Henderson NC,Kalia N,Frampton J,Adams DH,Newsome PN
11-0454 was used in Flow cytometry/Cell sorting to investigate the role of sphingosine-1-phosphate in the response of hematopoietic stem cells to liver fibrosis in mice.
Sat Jul 01 00:00:00 EDT 2017
Differential cytokine contributions of perivascular haematopoietic stem cell niches.
Nature cell biology
Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS
11-0454 was used in Flow cytometry/Cell sorting to demonstrate that the effects of cytokines regulating haematopoietic stem cell functions are dependent on the producing cell sources.
Wed Mar 01 00:00:00 EST 2017
Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.
The Journal of experimental medicine
Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Mon Jun 05 00:00:00 EDT 2017
Macrophage deficiency of miR-21 promotes apoptosis, plaque necrosis, and vascular inflammation during atherogenesis.
EMBO molecular medicine
Canfrán-Duque A,Rotllan N,Zhang X,Fernández-Fuertes M,Ramírez-Hidalgo C,Araldi E,Daimiel L,Busto R,Fernández-Hernando C,Suárez Y
11-0454 was used in Flow cytometry/Cell sorting to reveal a major role for hematopoietic miR-21 in atherogenesis.
Fri Sep 01 00:00:00 EDT 2017
Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells.
Oncotarget
Guo XL,Chu L,Ke F,Mu LL,Li Z,Cai JJ,Li HF,Hong DL
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Tue Dec 12 00:00:00 EST 2017
Pneumocystis-Driven Inducible Bronchus-Associated Lymphoid Tissue Formation Requires Th2 and Th17 Immunity.
Cell reports
Eddens T,Elsegeiny W,Garcia-Hernadez ML,Castillo P,Trevejo-Nunez G,Serody K,Campfield BT,Khader SA,Chen K,Rangel-Moreno J,Kolls JK
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Tue Mar 28 00:00:00 EDT 2017
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity.
Nature communications
Zamarin D,Holmgaard RB,Ricca J,Plitt T,Palese P,Sharma P,Merghoub T,Wolchok JD,Allison JP
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Mon Feb 13 00:00:00 EST 2017
Hepatic stroma-educated regulatory DCs suppress CD8+ T cell proliferation in mice.
Oncotarget
Wang Q,He H,Chen D,Wang C,Xu Y,Song W
11-0454 was used in Flow cytometry/Cell sorting to assess whether and how liver dendritic cells suppress CD8+ T cells.
Tue Nov 07 00:00:00 EST 2017
Small molecule p300/catenin antagonist enhances hematopoietic recovery after radiation.
PloS one
Zhao Y,Wu K,Nguyen C,Smbatyan G,Melendez E,Higuchi Y,Chen Y,Kahn M
11-0454 was used in Flow cytometry/Cell sorting to report that the small molecule YH250 stimulates hematopoiesis in lethally or sublethally irradiated mice.
Tue Sep 26 00:00:00 EDT 2017
Blocking IL-10 signalling at the time of immunization does not increase unwanted side effects in mice.
BMC immunology
Ni G,Liao Z,Chen S,Wang T,Yuan J,Pan X,Mounsey K,Cavezza S,Liu X,Wei MQ
11-0454 was used in Flow cytometry/Cell sorting to determine the effect of blocking IL-10 during immunisation on intestinal inflammation responses.
Tue Aug 15 00:00:00 EDT 2017
Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.
Cell
Chudnovskiy A,Mortha A,Kana V,Kennard A,Ramirez JD,Rahman A,Remark R,Mogno I,Ng R,Gnjatic S,Amir ED,Solovyov A,Greenbaum B,Clemente J,Faith J,Belkaid Y,Grigg ME,Merad M
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Thu Oct 06 00:00:00 EDT 2016
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Thu Aug 25 00:00:00 EDT 2016
DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas.
Cell
Herrtwich L,Nanda I,Evangelou K,Nikolova T,Horn V,Erny D,Stefanowski J,Rogell L,Klein C,Gharun K,Follo M,Seidl M,Kremer B,Münke N,Senges J,Fliegauf M,Aschman T,Pfeifer D,Sarrazin S,Sieweke MH,Wagner D,Dierks C,Haaf T,Ness T,Zaiss MM,Voll RE,Deshmukh SD,Prinz M,Goldmann T,Hölscher C,Hauser AE,Lopez-Contreras AJ,Grün D,Gorgoulis V,Diefenbach A,Henneke P,Triantafyllopoulou A
11-0454 was used in Immunohistochemistry-immunofluorescence to study the molecular programs that control differentiation of macrophage populations in response to chronic stimulus.
Thu Nov 17 00:00:00 EST 2016
DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas.
Cell
Herrtwich L,Nanda I,Evangelou K,Nikolova T,Horn V,Erny D,Stefanowski J,Rogell L,Klein C,Gharun K,Follo M,Seidl M,Kremer B,Münke N,Senges J,Fliegauf M,Aschman T,Pfeifer D,Sarrazin S,Sieweke MH,Wagner D,Dierks C,Haaf T,Ness T,Zaiss MM,Voll RE,Deshmukh SD,Prinz M,Goldmann T,Hölscher C,Hauser AE,Lopez-Contreras AJ,Grün D,Gorgoulis V,Diefenbach A,Henneke P,Triantafyllopoulou A
11-0454 was used in Immunohistochemistry-immunofluorescence to study the molecular programs that control differentiation of macrophage populations in response to chronic stimulus.
Thu Nov 17 00:00:00 EST 2016
Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal.
Nature cell biology
Pietras EM,Mirantes-Barbeito C,Fong S,Loeffler D,Kovtonyuk LV,Zhang S,Lakshminarasimhan R,Chin CP,Techner JM,Will B,Nerlov C,Steidl U,Manz MG,Schroeder T,Passegué E
11-0454 was used in Flow cytometry/Cell sorting to identify a critical regulatory circuit that tailors HSC responses to acute needs, and is likely to underlie deregulated blood homeostasis in chronic inflammation conditions.
Wed Jun 01 00:00:00 EDT 2016
CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses.
The Journal of experimental medicine
Chong SZ,Evrard M,Devi S,Chen J,Lim JY,See P,Zhang Y,Adrover JM,Lee B,Tan L,Li JL,Liong KH,Phua C,Balachander A,Boey A,Liebl D,Tan SM,Chan JK,Balabanian K,Harris JE,Bianchini M,Weber C,Duchene J,Lum J,Poidinger M,Chen Q,Rénia L,Wang CI,Larbi A,Randolph GJ,Weninger W,Looney MR,Krummel MF,Biswas SK,Ginhoux F,Hidalgo A,Bachelerie F,Ng LG
11-0454 was used in Flow cytometry/Cell sorting to demonstrate the multifaceted role of CXCR4 in defining BM monocyte heterogeneity and in regulating their function in peripheral tissues.
Mon Oct 17 00:00:00 EDT 2016
Repurposing Treprostinil for Enhancing Hematopoietic Progenitor Cell Transplantation.
Molecular pharmacology
Kazemi Z,Bergmayr C,Prchal-Murphy M,Javaheri T,Themanns M,Pham HT,Strohmaier W,Sexl V,Freissmuth M,Zebedin-Brandl E
11-0454 was used in Flow cytometry/Cell sorting to assess whether treprostinil, a prostacyclin analog, could be repurposed to improve hematopoietic stem cell transplantation.
Wed Jun 01 00:00:00 EDT 2016
Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.
Stem cell reports
Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Tue Aug 09 00:00:00 EDT 2016
LTβR controls thymic portal endothelial cells for haematopoietic progenitor cell homing and T-cell regeneration.
Nature communications
Shi Y,Wu W,Chai Q,Li Q,Hou Y,Xia H,Ren B,Xu H,Guo X,Jin C,Lv M,Wang Z,Fu YX,Zhu M
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Immunofluorescence
Fri Aug 05 00:00:00 EDT 2016
Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development.
Cell reports
Barrett NA,Malouf C,Kapeni C,Bacon WA,Giotopoulos G,Jacobsen SEW,Huntly BJ,Ottersbach K
11-0454 was used in Flow cytometry/Cell sorting to elucidate the contribution of MII-AF4 in B cell acute lymphoblastic leukaemia early development in the mouse embryo.
Tue Jul 26 00:00:00 EDT 2016
Fat-associated lymphoid clusters control local IgM secretion during pleural infection and lung inflammation.
Nature communications
Jackson-Jones LH,Duncan SM,Magalhaes MS,Campbell SM,Maizels RM,McSorley HJ,Allen JE,Bénézech C
11-0454 was used in Immunofluorescence to reveal a link between inflammation, IL-33 release by FALC stromal cells, ILC2 activation and pleural B-cell activation in FALCs, resulting in local and antigen-specific IgM production.
Thu Sep 01 00:00:00 EDT 2016
Fat-associated lymphoid clusters control local IgM secretion during pleural infection and lung inflammation.
Nature communications
Jackson-Jones LH,Duncan SM,Magalhaes MS,Campbell SM,Maizels RM,McSorley HJ,Allen JE,Bénézech C
11-0454 was used in Immunofluorescence to reveal a link between inflammation, IL-33 release by FALC stromal cells, ILC2 activation and pleural B-cell activation in FALCs, resulting in local and antigen-specific IgM production.
Thu Sep 01 00:00:00 EDT 2016
Endothelium-targeted human Delta-like 1 enhances the regeneration and homing of human cord blood stem and progenitor cells.
Journal of translational medicine
Tian DM,Liang YM,Zhang YQ
11-0454 was used in Flow cytometry/Cell sorting to investigate the effects of endothelium-targeted human Delta-like 1 on human umbilical cord blood hematopoietic stem and progenitor cells.
Wed Jan 06 00:00:00 EST 2016
Genome-wide gene expression analyses reveal unique cellular characteristics related to the amenability of HPC/HSCs into high-quality induced pluripotent stem cells.
Stem cell research & therapy
Gao S,Tao L,Hou X,Xu Z,Liu W,Zhao K,Guo M,Wang H,Cai T,Tian J,Gao S,Chang G
11-0454 was used in Flow cytometry/Cell sorting to elucidate the mechanisms of haematopoietic progenitor and stem cell reprogramming into induced pluripotent stem cells.
Tue Mar 15 00:00:00 EDT 2016
Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS.
Nature
Krönke J,Fink EC,Hollenbach PW,MacBeth KJ,Hurst SN,Udeshi ND,Chamberlain PP,Mani DR,Man HW,Gandhi AK,Svinkina T,Schneider RK,McConkey M,Järås M,Griffiths E,Wetzler M,Bullinger L,Cathers BE,Carr SA,Chopra R,Ebert BL
11-0454 was used in Flow cytometry/Cell sorting to demonstrate the ubiquitination dependent mechanism by which lenalidomide induces the degradation of casein kinase 1A1 in del(5q) myelodysplastic syndrome.
Thu Jul 09 00:00:00 EDT 2015
Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System.
Immunity
Bruttger J,Karram K,Wörtge S,Regen T,Marini F,Hoppmann N,Klein M,Blank T,Yona S,Wolf Y,Mack M,Pinteaux E,Müller W,Zipp F,Binder H,Bopp T,Prinz M,Jung S,Waisman A
11-0454 was used in Flow cytometry/Cell sorting to study how microglia have the potential for efficient self-renewal without the contribution of peripheral myeloid cells, and IL-1R signaling participates in this restorative proliferation process.
Tue Jul 21 00:00:00 EDT 2015
BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival.
The Journal of experimental medicine
Jacque E,Schweighoffer E,Tybulewicz VL,Ley SC
11-0454 was used in Flow cytometry/Cell sorting to reveal a potentially critical role for the MEK5-ERK5 MAP kinase signalling pathway in BAFF-induced mature B cell survival and homeostatic maintenance of B2 cell numbers.
Mon Jun 01 00:00:00 EDT 2015
Atypical chemokine receptor 1 deficiency reduces atherogenesis in ApoE-knockout mice.
Cardiovascular research
Wan W,Liu Q,Lionakis MS,Marino AP,Anderson SA,Swamydas M,Murphy PM
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
mir-181a-1/b-1 Modulates Tolerance through Opposing Activities in Selection and Peripheral T Cell Function.
Journal of immunology (Baltimore, Md. : 1950)
Schaffert SA,Loh C,Wang S,Arnold CP,Axtell RC,Newell EW,Nolan G,Ansel KM,Davis MM,Steinman L,Chen CZ
11-0454 was used in Flow cytometry/Cell sorting to explore the physiological control of tolerance by manipulating microRNA gene products.
Sat Aug 15 00:00:00 EDT 2015
A genome-wide analysis identifies a notch-RBP-Jκ-IL-7Rα axis that controls IL-17-producing γδ T cell homeostasis in mice.
Journal of immunology (Baltimore, Md. : 1950)
Nakamura M,Shibata K,Hatano S,Sato T,Ohkawa Y,Yamada H,Ikuta K,Yoshikai Y
11-0454 was used in Flow cytometry/Cell sorting to investigate additional roles for the Notch axis in the homeostasis of γδ T cells.
Thu Jan 01 00:00:00 EST 2015
Frizzled-6 Regulates Hematopoietic Stem/Progenitor Cell Survival and Self-Renewal.
Journal of immunology (Baltimore, Md. : 1950)
Abidin BM,Owusu Kwarteng E,Heinonen KM
11-0454 was used in Flow cytometry/Cell sorting to reveal that Fzd6 has an essential role in HSPC maintenance and survival.
Tue Sep 01 00:00:00 EDT 2015
Axitinib increases the infiltration of immune cells and reduces the suppressive capacity of monocytic MDSCs in an intracranial mouse melanoma model.
Oncoimmunology
Du Four S,Maenhout SK,De Pierre K,Renmans D,Niclou SP,Thielemans K,Neyns B,Aerts JL
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Dipeptide species regulate p38MAPK-Smad3 signalling to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Jomen Y,Ishihara K,Kim J,Ishimoto T,Bae EJ,Mohney RP,Stirdivant SM,Oshima H,Oshima M,Kim DW,Nakauchi H,Takihara Y,Kato Y,Ooshima A,Kim SJ
11-0454 was used in Flow cytometry/Cell sorting to investigate how survival signalling is regulated in chronic myelogenous leukaemia stem cells, showing that dipeptide species regulate p38MAPK-Smad3 signalling to maintain stem cells.
Thu Aug 20 00:00:00 EDT 2015
Focal MMP-2 and MMP-9 activity at the blood-brain barrier promotes chemokine-induced leukocyte migration.
Cell reports
Song J,Wu C,Korpos E,Zhang X,Agrawal SM,Wang Y,Faber C,Schäfers M,Körner H,Opdenakker G,Hallmann R,Sorokin L
11-0454 was used in Flow cytometry/Cell sorting to conclude that cytokines, chemokines, and cytokine-induced MMP-2/9 activity specifically at the inflammatory border collectively act to accelerate leukocyte chemotaxis across the parenchymal border.
Tue Feb 24 00:00:00 EST 2015
Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphoma.
Nature communications
Lee CL,Castle KD,Moding EJ,Blum JM,Williams N,Luo L,Ma Y,Borst LB,Kim Y,Kirsch DG
11-0454 was used in Flow cytometry/Cell sorting to show that total-body irradiation promotes the expansion of a rare population of thymocytes that express oncogenic Kras(G12D).
Thu Sep 24 00:00:00 EDT 2015
Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion.
Nature medicine
Bruns I,Lucas D,Pinho S,Ahmed J,Lambert MP,Kunisaki Y,Scheiermann C,Schiff L,Poncz M,Bergman A,Frenette PS
11-0454 was used in Flow cytometry/Cell sorting to indicate that a terminally differentiated cell type derived from HSCs contributes to the HSC niche, directly regulating HSC behavior.
Sat Nov 01 00:00:00 EDT 2014
Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells.
Nature
Flach J,Bakker ST,Mohrin M,Conroy PC,Pietras EM,Reynaud D,Alvarez S,Diolaiti ME,Ugarte F,Forsberg EC,Le Beau MM,Stohr BA,Méndez J,Morrison CG,Passegué E
11-0454 was used in Flow cytometry/Cell sorting to study functional decline in ageing haematopoietic stem cells due to replicative stress.
Thu Aug 14 00:00:00 EDT 2014
WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.
The Journal of experimental medicine
Xia P,Wang S,Huang G,Zhu P,Li M,Ye B,Du Y,Fan Z
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Mon Sep 22 00:00:00 EDT 2014
BMP4 inhibits breast cancer metastasis by blocking myeloid-derived suppressor cell activity.
Cancer research
Cao Y,Slaney CY,Bidwell BN,Parker BS,Johnstone CN,Rautela J,Eckhardt BL,Anderson RL
11-0454 was used in Flow cytometry/Cell sorting to assess the potential for therapies based on the activation of BMP4 signalling for the treatment of breast cancer.
Mon Sep 15 00:00:00 EDT 2014
CD41 is a reliable identification and activation marker for murine basophils in the steady state and during helminth and malarial infections.
European journal of immunology
Bakocevic N,Claser C,Yoshikawa S,Jones LA,Chew S,Goh CC,Malleret B,Larbi A,Ginhoux F,de Lafaille MC,Karasuyama H,Renia L,Ng LG
11-0454 was used in Flow cytometry/Cell sorting to study the CD41 expression within basophils from the blood during both steady state and malarial inections within mice.
Sun Jun 01 00:00:00 EDT 2014
IFN-γ-producing and IL-17-producing γδ T cells differentiate at distinct developmental stages in murine fetal thymus.
Journal of immunology (Baltimore, Md. : 1950)
Shibata K,Yamada H,Nakamura M,Hatano S,Katsuragi Y,Kominami R,Yoshikai Y
11-0454 was used in Flow cytometry/Cell sorting to compare the functions of γδ T cells derived from double-negative 2 and double-negative 3 cells in the murine fetal thymus.
Sat Mar 01 00:00:00 EST 2014
E and Id proteins influence invariant NKT cell sublineage differentiation and proliferation.
Journal of immunology (Baltimore, Md. : 1950)
D'Cruz LM,Stradner MH,Yang CY,Goldrath AW
11-0454 was used in Flow cytometry/Cell sorting to investigate the mechanism by which E and Id proteins control the development of invariant NKT sublineages after positive selection.
Sat Mar 01 00:00:00 EST 2014
Th2-type inflammation instructs inflammatory dendritic cells to induce airway hyperreactivity.
International immunology
Iwata A,Kawashima S,Kobayashi M,Okubo A,Kawashima H,Suto A,Hirose K,Nakayama T,Nakajima H
11-0454 was used in Flow cytometry/Cell sorting to indicate the importance of iDCs in the induction of AHR as downstream effector cells in Th2 cell-mediated asthmatic responses.
Sat Feb 01 00:00:00 EST 2014
Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface.
PloS one
Habbeddine M,Verbeke P,Karaz S,Bobé P,Kanellopoulos-Langevin C
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Wed Jun 10 00:00:00 EDT 2015
Foxp3 expression in macrophages associated with RENCA tumors in mice.
PloS one
Devaud C,Yong CS,John LB,Westwood JA,Duong CP,House CM,Denoyer D,Li J,Darcy PK,Kershaw MH
11-0454 was used in Flow cytometry/Cell sorting to study how tumour-associated macrophages could express Foxp3.
Mon Nov 16 00:00:00 EST 2015
Usp16 contributes to somatic stem-cell defects in Down's syndrome.
Nature
Adorno M,Sikandar S,Mitra SS,Kuo A,Nicolis Di Robilant B,Haro-Acosta V,Ouadah Y,Quarta M,Rodriguez J,Qian D,Reddy VM,Cheshier S,Garner CC,Clarke MF
11-0454 was used in Flow cytometry/Cell sorting to demonstrate a role for USP16 in antagonising the self-renewal and senescence pathways in Down's syndrome.
Thu Sep 19 00:00:00 EDT 2013
FOXO3A directs a protective autophagy program in haematopoietic stem cells.
Nature
Warr MR,Binnewies M,Flach J,Reynaud D,Garg T,Malhotra R,Debnath J,Passegué E
11-0454 was used in Flow cytometry/Cell sorting to show how FOXO3A directs a protective autophagy program in haematopoietic stem cells.
Thu Feb 21 00:00:00 EST 2013
Arteriolar niches maintain haematopoietic stem cell quiescence.
Nature
Kunisaki Y,Bruns I,Scheiermann C,Ahmed J,Pinho S,Zhang D,Mizoguchi T,Wei Q,Lucas D,Ito K,Mar JC,Bergman A,Frenette PS
11-0454 was used in Flow cytometry/Cell sorting to investigate the spatial localisation of quiescent haematopoietic stem cells in bone marrow, showing that arteriolar niches maintain quiescence.
Thu Oct 31 00:00:00 EDT 2013
Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4⁺ T cell immunity.
Nature immunology
Reis BS,Rogoz A,Costa-Pinto FA,Taniuchi I,Mucida D
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis.
Nature cell biology
Zhang Y,Yang P,Sun T,Li D,Xu X,Rui Y,Li C,Chong M,Ibrahim T,Mercatali L,Amadori D,Lu X,Xie D,Li QJ,Wang XF
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
Early immunisation with dendritic cells after allogeneic bone marrow transplantation elicits graft vs tumour reactivity.
British journal of cancer
Gigi V,Stein J,Askenasy N,Yaniv I,Ash S
11-0454 was used in Flow cytometry/Cell sorting to assess the impact of dendritic cell immunisation on graft vs tumour reactions triggered by allogeneic bone marrow transplantation.
Tue Mar 19 00:00:00 EDT 2013
Sca1-derived cells are a source of myocardial renewal in the murine adult heart.
Stem cell reports
Uchida S,De Gaspari P,Kostin S,Jenniches K,Kilic A,Izumiya Y,Shiojima I,Grosse Kreymborg K,Renz H,Walsh K,Braun T
11-0454 was used in Flow cytometry/Cell sorting to reveal a source of cells for cardiomyocyte renewal, providing explanation for the limited contribution of Sca1-derived cells to myocardial repair.
Mon Oct 26 00:00:00 EDT 2015
Arrayed lentiviral barcoding for quantification analysis of hematopoietic dynamics.
Stem cells (Dayton, Ohio)
Grosselin J,Sii-Felice K,Payen E,Chretien S,Tronik-Le Roux D,Leboulch P
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2013
A C-terminal acidic domain regulates degradation of the transcriptional coactivator Bob1.
Molecular and cellular biology
Lindner JM,Wong CS,Möller A,Nielsen PJ
11-0454 was used in Flow cytometry/Cell sorting to analyse the stability of the protein Bob1 in response to genetic and physiological perturbations.
Sun Dec 01 00:00:00 EST 2013
The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects.
The Journal of biological chemistry
Zamanian-Daryoush M,Lindner D,Tallant TC,Wang Z,Buffa J,Klipfell E,Parker Y,Hatala D,Parsons-Wingerter P,Rayman P,Yusufishaq MSS,Fisher EA,Smith JD,Finke J,DiDonato JA,Hazen SL
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Flow Cytometry
Fri Jul 19 00:00:00 EDT 2013
G-CSF/anti-G-CSF antibody complexes drive the potent recovery and expansion of CD11b+Gr-1+ myeloid cells without compromising CD8+ T cell immune responses.
Journal of hematology & oncology
Rubinstein MP,Salem ML,Doedens AL,Moore CJ,Chiuzan C,Rivell GL,Cole DJ,Goldrath AW
11-0454 was used in Flow cytometry/Cell sorting to evaluate whether the biological activity of G-CSF can be improved by pre-association with anti-G-CSF monoclonal antibodies prior to injection.
Tue Oct 01 00:00:00 EDT 2013
Plasmacytoid dendritic cells transport peripheral antigens to the thymus to promote central tolerance.
Immunity
Hadeiba H,Lahl K,Edalati A,Oderup C,Habtezion A,Pachynski R,Nguyen L,Ghodsi A,Adler S,Butcher EC
11-0454 was used in Flow cytometry/Cell sorting to explore the mechanisms underlying the contribution to immune tolerance conducted by peripheral dendritic cells.
Fri Mar 23 00:00:00 EDT 2012
Type I interferons maintain Foxp3 expression and T-regulatory cell functions under inflammatory conditions in mice.
Gastroenterology
Lee SE,Li X,Kim JC,Lee J,González-Navajas JM,Hong SH,Park IK,Rhee JH,Raz E
11-0454 was used in Flow cytometry/Cell sorting to study the role of type I interferons during intestinal homeostasis regulation in a T cell-induced colitis mouse model.
Sun Jul 01 00:00:00 EDT 2012
The location of splenic NKT cells favours their rapid activation by blood-borne antigen.
The EMBO journal
Barral P,Sánchez-Niño MD,van Rooijen N,Cerundolo V,Batista FD
11-0454 was used in Flow cytometry/Cell sorting to study the distribution and dynamics of natural killer T cells within the spleen.
Wed May 16 00:00:00 EDT 2012
Aberrant macrophages mediate defective kidney repair that triggers nephritis in lupus-susceptible mice.
Journal of immunology (Baltimore, Md. : 1950)
Iwata Y,Boström EA,Menke J,Rabacal WA,Morel L,Wada T,Kelley VR
11-0454 was used in Flow cytometry/Cell sorting to elucidate the macrophage-associated effects of CSF-1 expression by tubular epithelial cells during kidney inflammation.
Tue May 01 00:00:00 EDT 2012
A critical role for Rictor in T lymphopoiesis.
Journal of immunology (Baltimore, Md. : 1950)
Tang F,Wu Q,Ikenoue T,Guan KL,Liu Y,Zheng P
11-0454 was used in Flow cytometry/Cell sorting to investigate the signalling pathway required for T lymphopoiesis, showing a critical role for Rictor.
Wed Aug 15 00:00:00 EDT 2012
Interleukin-15 treatment induces weight loss independent of lymphocytes.
PloS one
Barra NG,Chew MV,Reid S,Ashkar AA
11-0454 was used in Flow cytometry/Cell sorting to determine if lymphocytes, particularly natural killer cells, play a role in Interleukin-15 mediated weight loss.
Tue Nov 27 00:00:00 EST 2012
DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice.
The Journal of experimental medicine
Randall KL,Chan SS,Ma CS,Fung I,Mei Y,Yabas M,Tan A,Arkwright PD,Al Suwairi W,Lugo Reyes SO,Yamazaki-Nakashimada MA,Garcia-Cruz Mde L,Smart JM,Picard C,Okada S,Jouanguy E,Casanova JL,Lambe T,Cornall RJ,Russell S,Oliaro J,Tangye SG,Bertram EM,Goodnow CC
11-0454 was used in Flow cytometry/Cell sorting to study the role of DOCK8 in the survival and function of human and mouse CD8 T cells.
Mon Oct 24 00:00:00 EDT 2011
Hydrodynamic delivery of human IL-15 cDNA increases murine natural killer cell recovery after syngeneic bone marrow transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
Barao I,Alvarez M,Redelman D,Weiss JM,Ortaldo JR,Wiltrout RH,Murphy WJ
11-0454 was used in Flow cytometry/Cell sorting to highlight cytokine gene transfer-based methods as a potential platform for natural killer cell recovery after bone marrow transplantation in mice.
Thu Dec 01 00:00:00 EST 2011
Clonal analysis reveals uniformity in the molecular profile and lineage potential of CCR9(+) and CCR9(-) thymus-settling progenitors.
Journal of immunology (Baltimore, Md. : 1950)
Desanti GE,Jenkinson WE,Parnell SM,Boudil A,Gautreau-Rolland L,Eksteen B,Ezine S,Lane PJ,Jenkinson EJ,Anderson G
11-0454 was used in Flow cytometry/Cell sorting to suggest that the earliest T cell progenitors represent a developmentally homogeneous progenitor pool that ensures the efficient generation of the first cohorts of T cells during thymus development.
Sun May 01 00:00:00 EDT 2011
Notch3 is dispensable for thymocyte β-selection and Notch1-induced T cell leukemogenesis.
PloS one
Suliman S,Tan J,Xu K,Kousis PC,Kowalski PE,Chang G,Egan SE,Guidos C
11-0454 was used in Flow cytometry/Cell sorting to assess the essentiality of Notch3 signalling for T cell development and leukaemogenesis.
Tue Feb 28 00:00:00 EST 2012
Ontogeny of stromal organizer cells during lymph node development.
Journal of immunology (Baltimore, Md. : 1950)
Bénézech C,White A,Mader E,Serre K,Parnell S,Pfeffer K,Ware CF,Anderson G,Caamaño JH
11-0454 was used in Flow cytometry/Cell sorting to highlight the importance of the signals and cellular interactions that induce the maturation of stromal cells.
Thu Apr 15 00:00:00 EDT 2010
The NOD/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infection.
PLoS pathogens
Shimada K,Chen S,Dempsey PW,Sorrentino R,Alsabeh R,Slepenkin AV,Peterson E,Doherty TM,Underhill D,Crother TR,Arditi M
11-0454 was used in Flow cytometry/Cell sorting to investigate the role of the Nod/Rip2 pathway in responses to Chlamydophila pneumoniae infection, showing that it is essential for host defences against pneumonia.
Wed Apr 01 00:00:00 EDT 2009
Recall responses by helpless memory CD8+ T cells are restricted by the up-regulation of PD-1.
Journal of immunology (Baltimore, Md. : 1950)
Fuse S,Tsai CY,Molloy MJ,Allie SR,Zhang W,Yagita H,Usherwood EJ
11-0454 was used in Flow cytometry/Cell sorting to identify molecular pathways involved in CD4 help for generation of TRAIL independent memory CD8(+) T cells.
Wed Apr 01 00:00:00 EDT 2009
IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response.
Blood
Rubinstein MP,Lind NA,Purton JF,Filippou P,Best JA,McGhee PA,Surh CD,Goldrath AW
11-0454 was used in Flow cytometry/Cell sorting to study IL-7 and IL-15 regulation of CD8+ T-cell subsets during contraction of the immune response.
Sat Nov 01 00:00:00 EDT 2008
CXCL9, but not CXCL10, promotes CXCR3-dependent immune-mediated kidney disease.
Journal of the American Society of Nephrology : JASN
Menke J,Zeller GC,Kikawada E,Means TK,Huang XR,Lan HY,Lu B,Farber J,Luster AD,Kelley VR
11-0454 was used in Flow cytometry/Cell sorting to identify additional therapeutic chemokine targets for immune-mediated nephritis.
Sun Jun 01 00:00:00 EDT 2008
IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype.
Proceedings of the National Academy of Sciences of the United States of America
Huber M,Brüstle A,Reinhard K,Guralnik A,Walter G,Mahiny A,von Löw E,Lohoff M
11-0454 was used in Flow cytometry/Cell sorting to investigate the role of IRF4 in Th17 differentiation, showing that it is essential for IL-21-mediated induction, amplification, and stabilisation of the Th17 phenotype.
Tue Dec 30 00:00:00 EST 2008
Defective positive selection results in T cell lymphopenia and increased autoimmune diabetes in ADAP-deficient BDC2.5-C57BL/6 mice.
European journal of immunology
Zou L,Mendez F,Martin-Orozco N,Peterson EJ
11-0454 was used in Flow cytometry/Cell sorting to investigate the role of ADAP in a T cell-driven autoimmune response, showing that deficiency leads to defective positive selection in T cell lymphopenia and increased autoimmune diabetes.
Tue Apr 01 00:00:00 EDT 2008
Combined anti-CD40 conditioning and well-timed immunization prolongs CD8+ T cell accumulation and control of established brain tumors.
Journal of immunotherapy (Hagerstown, Md. : 1997)
Ryan CM,Staveley-O'Carroll K,Schell TD
11-0454 was used in Flow cytometry/Cell sorting to investigate the augmentation of CD8+ T-cell-mediated adoptive immunotherapy by targeting a weakly immunogenic epitope.
Mon Jul 13 00:00:00 EDT 2009
Lymphotoxin a-dependent and -independent signals regulate stromal organizer cell homeostasis during lymph node organogenesis.
Blood
White A,Carragher D,Parnell S,Msaki A,Perkins N,Lane P,Jenkinson E,Anderson G,Caamaño JH
11-0454 was used in Flow cytometry/Cell sorting to further investigate the mechanisms that regulate the development of stromal organiser cells.
Sat Sep 15 00:00:00 EDT 2007
Presenilins regulate alphabeta T cell development by modulating TCR signaling.
The Journal of experimental medicine
Laky K,Fowlkes BJ
11-0454 was used in Flow cytometry/Cell sorting to suggest a model in which PS-dependent Notch signalling influences positive selection and the development of alphabeta T cells by modifying TCR signal transduction.
Mon Sep 03 00:00:00 EDT 2007
Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1.
Molecular biology of the cell
Hansen DV,Loktev AV,Ban KH,Jackson PK
Published figure using CD45.2 monoclonal antibody (Product # 11-0454-82) in Western Blot
Wed Dec 01 00:00:00 EST 2004
