Visualize your imaging data and obtain qualitative and quantitative information such as volume, density and diameter, from a single software environment.

Anatomical image analysis relies on augmenting structural information from micro-CT or MRI systems with functional data from PET, SPECT or optical imaging instrumentation. Analysis of novel drug candidates requires pinpointing the location of dynamic processes acquired with functional modalities in images of the animal’s anatomy from structural modalities over time.

Amira Software enables the fusion of any type of anatomical image data. Co-registered images can be segmented and analyzed using Amira Software’s vast library of image analysis filters and algorithms. Image segmentation and quantification workflows can be applied to entire time series of image data of dynamic processes. With Amira Software’s professional-grade visualization tools, structural information from CT and MRI can be augmented and rendered jointly with segmentation results and functional images to create visualization of physiological processes that reveal the underlying mechanisms in an intuitive animation.

 

Imaging data

Workflow using Avizo Software

Processing

Workflow using Avizo Software

Visualization

Workflow using Avizo Software

Analysis

Workflow using Avizo Software

 

 

 

カスタマイズ

信頼性

当社のデジタルイメージングベースのワークフローは、パワフルなセグメンテーションや画像処理能力およびワークフローを備えており、また科学コミュニティや数千人もの研究者との20年以上にわたるコラボレーション実績があるため、生物医学およびライフサイエンスの研究において信頼できる答えを提供することが実証されています。

カスタマイズ

カスタマイズ

お客様のニーズはそれぞれ異なり、常に進化しているため、当社のソフトウェアソリューションは非常に柔軟で、自由にカスタマイズできます。当社のスクリプトインターフェース(Python、TCL)、MATLABとのブリッジ、およびプログラミングAPIを利用することにより、当社のソフトウェアソリューションを拡張し、お客様独自のIP(知的財産)を統合できます。また必要に応じて、当社のプロフェッショナルサービスチームがお客様のニーズに合わせた独自ソリューションの設計をお手伝いします。

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サポート

当社は専用のプロフェッショナルサポートチームを配備しているため、トップエキスパートに問い合わせて、あらゆる質問に対する回答を得ることができます。また、当社のトレーニングやコンサルティングオプション、拡張し続けているチュートリアルやハウ・ツーを活用することで学習時間を短縮し、追求している答えを見つけることに集中できます。

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自動化

自動化機能や拡大を続けるアドオンのオンラインレポジトリ(Xtra Gallery)により、繰り返し可能なワークフローを再現が容易なレシピに変換きます。人工知能が追加されているため、画像処理専門家以外でも分析が可能で、複雑な分析に費やす時間を短縮しながら結果の一貫性を維持できます。

 

Scientific use cases using Amira Software

 

 

Testimonials

 

VetCore, University of Veterinary Medicine uses Amira Software

"Research at Vetmeduni Vienna is quite diverse, covering both clinical and preclinical research areas. We are currently four people working in the imaging facility, providing equipment and supports for researchers in both image acquisition (widefield microscopy, CLSM, spinning disk confocal microscopy, soon also STORM super-resolution microscopy, microscopic X-ray computed tomography) and in data visualization and analysis. Amira Software allows you to build networks, enabling complex interactions between data objects. Biology is also complex, and biological interactions are complex networks. Complex questions require complex tools to address them. In this respect, analysis networks such as used in Amira Software outperform most other software approaches when it comes to complex data analysis. Furthermore, I like that Amira Software is quite open concerning integration of deep learning networks and scripting (Tcl, Matlab, Python,...)."

Stephan Handschuch, PhD
VetCore, University of Veterinary Medicine, Vienna


Insight from your peers

Explore industry-leading insights and research that can support your lab workflow. Amira Software can empower your lab with a cutting-edge, comprehensive imaging data analysis toolbox.

Helping scientists answer questions that enable breakthrough discoveries in life sciences, materials science, and industry.

Correlative Microscopy: Using Amira Software to Understand the Spread of Cancer
Read more
Amira Software Accelerates Veterinary Research with 3D Visualization and Analysis
Read more
Molecular Clarity—Discovering What’s Possible with Cryo-Electron Tomography
Read more
Cryo-Electron Tomography and 3D Software Advances Coronavirus Research
Read more

 

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Techniques and tools within Amira Software for anatomical biology

 

Co-registration

One of the main reasons researchers are using preclinical imaging is in vivo distribution studies aimed at localizing therapeutic agents in drug or gene therapy. These agents are often tagged or made susceptible for tagging with radioactive nuclei for detection with PET or SPECT imaging instruments.

With its extensive, performance-optimized registration tools and its multi-volume architecture, Amira Software allows preclinical researchers to automatically co-register image data from any type of preclinical imaging instrumentation. Amira Software’s extensive toolbox of segmentation and quantification tools then allows for segmentation of the anatomical images and quantifying radiotracer uptake in the co-registered functional images.

 

Bone separation

Micro-CT image acquisition is one of the most popular imaging techniques for any type of bone research. One of the first steps for any bone analysis is bone segmentation and separation into individual bones.

Amira Software offers the tools to perform bone segmentation from the surrounding tissue. The segmented bones can then be separated with Amira Software’s advanced algorithms. The individual bones can then be measured using a customizable list of the many measurements that Amira Software provides, such as size, shape and orientation.

 

Cell detection

Cellular spheroids are 3D cell cultures that represent in vivo tissue better than traditional cellular monolayers, improving the ability of researchers to study cancer, diabetes mellitus, or stem cells among many applications.

However, cell analysis in such 3D multicellular objects is not accurately possible, especially without destroying the object of study. Amira Software can automatically separate the cells and perform volumetric, morphometric, and intensity measurements on individual cells and their nuclei in 3D image data of these spheroids. Amira Software also helps researchers with the analysis of conventional 2D cellular monolayers.

 

Correlative imaging

With its long-standing applications in multi-modality imaging techniques, Amira Software is the tool of choice for many researchers working with data from different imaging modalities. Amira Software’s architecture supports multi-volume data processing and visualization from the ground up.

The automatic registration tools integrated into the standard edition of Amira Software with the Multi-Planar Workroom offer the flexibility of the most commonly used automated registration metrics and optimizers. These allow for the adjustment of the registration parameters to meet the needs of your data.

 

Membrane detection

Amira Software accelerates segmentation by employing automated detection of cellular features, such as filaments and membranes.

By performing advanced image analysis and statistics on the cryo-tomograms, Amira Software combines data from these individual structures, averaging out noise and increasing contrast to create a composite model with higher resolution.

 

Co-registration

One of the main reasons researchers are using preclinical imaging is in vivo distribution studies aimed at localizing therapeutic agents in drug or gene therapy. These agents are often tagged or made susceptible for tagging with radioactive nuclei for detection with PET or SPECT imaging instruments.

With its extensive, performance-optimized registration tools and its multi-volume architecture, Amira Software allows preclinical researchers to automatically co-register image data from any type of preclinical imaging instrumentation. Amira Software’s extensive toolbox of segmentation and quantification tools then allows for segmentation of the anatomical images and quantifying radiotracer uptake in the co-registered functional images.

 

Bone separation

Micro-CT image acquisition is one of the most popular imaging techniques for any type of bone research. One of the first steps for any bone analysis is bone segmentation and separation into individual bones.

Amira Software offers the tools to perform bone segmentation from the surrounding tissue. The segmented bones can then be separated with Amira Software’s advanced algorithms. The individual bones can then be measured using a customizable list of the many measurements that Amira Software provides, such as size, shape and orientation.

 

Cell detection

Cellular spheroids are 3D cell cultures that represent in vivo tissue better than traditional cellular monolayers, improving the ability of researchers to study cancer, diabetes mellitus, or stem cells among many applications.

However, cell analysis in such 3D multicellular objects is not accurately possible, especially without destroying the object of study. Amira Software can automatically separate the cells and perform volumetric, morphometric, and intensity measurements on individual cells and their nuclei in 3D image data of these spheroids. Amira Software also helps researchers with the analysis of conventional 2D cellular monolayers.

 

Correlative imaging

With its long-standing applications in multi-modality imaging techniques, Amira Software is the tool of choice for many researchers working with data from different imaging modalities. Amira Software’s architecture supports multi-volume data processing and visualization from the ground up.

The automatic registration tools integrated into the standard edition of Amira Software with the Multi-Planar Workroom offer the flexibility of the most commonly used automated registration metrics and optimizers. These allow for the adjustment of the registration parameters to meet the needs of your data.

 

Membrane detection

Amira Software accelerates segmentation by employing automated detection of cellular features, such as filaments and membranes.

By performing advanced image analysis and statistics on the cryo-tomograms, Amira Software combines data from these individual structures, averaging out noise and increasing contrast to create a composite model with higher resolution.

 

 

Services

 

Amira-Avizo-Introductory-training_1160x600

初級者向けトレーニング

Amira、Avizo、およびPerGeosソフトウェアの新規ユーザー用に設計された初級者向けトレーニングは学習速度を高め、投資を最大化します。

このコースは講義と実践セッションで構成されています。トレーニング教材は、Amira、Avizo、およびPerGeosソフトウェアの基本的な特長や機能を取り上げています。

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上級者向けトレーニング

Amira、Avizo、およびPerGeosソフトウェアの既存ユーザー用に設計された上級者向けトレーニングは投資を最大化し、結果までの時間の短縮します。

このコースは講義と実践セッションで構成されています。トレーニング教材は、Amira、Avizo、およびPerGeosソフトウェアの高度な特長や機能を取り上げています。

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カスタム開発

サーモフィッシャーサイエンティフィックには25年以上にわたる3Dおよび画像処理の経験と、大小の規模の組織に提供してきたカスタムプロジェクトの実績があり、お客様の独自のニーズに合わせてソリューションを提供できます。

当社のソフトウェアソリューションをさまざまなレベルでカスタマイズおよび拡張できます。

 

Resources

 

Understanding the passage of air through the upper airways is crucial for planning corrective rhinosurgery when undisturbed airflow is inhibited by persistent obstructions or deformities.

Micro-CT image acquisition is one of the most popular imaging techniques for any type of bone research. One of the first steps for any bone analysis is bone segmentation and separation into individual bones.

Discover how Amira-Avizo Software enables the whole 3D printing workflow, from 2D image stack import, to 3D reconstruction and 3D meshing, right through to 3D printer compatible formats export. Data courtesy of National University of Singapore.

Amira Software can automatically count the cell nuclei which correspond to the cell count of the 3D spheroid cell cultures.

Discover the capabilities of Amira Software. Transforming image data into interactive 3D models, aiding anatomical biology. Navigate high-resolution imaging from MRI, CT, light microscopy, and electron microscopy.
Amira-Software-bone-separation_1160x600_image-card
Courtesy of National Laboratory Animal Center - National Applied Research Laboratories, Taiwan.
Amira-Software-coregistration_1160x600_image-card

Co-registration for distribution studies. CT/SPECT data courtesy of Dr. Nabil Boutagy of the Yale Translation Research Imaging Center.

Amira-Software-Preclinical_1160x600_image-card

Maximum intensity projection and surface reconstruction of a mouse thorax. Acquisition device: VAMP TomoScope® 30s+, Amira Software - Courtesy of Dr. Elizatea Stepina and Dr. Peter Hauff, Bayer Healthcare.

Understanding the passage of air through the upper airways is crucial for planning corrective rhinosurgery when undisturbed airflow is inhibited by persistent obstructions or deformities.

Micro-CT image acquisition is one of the most popular imaging techniques for any type of bone research. One of the first steps for any bone analysis is bone segmentation and separation into individual bones.

Discover how Amira-Avizo Software enables the whole 3D printing workflow, from 2D image stack import, to 3D reconstruction and 3D meshing, right through to 3D printer compatible formats export. Data courtesy of National University of Singapore.

Amira Software can automatically count the cell nuclei which correspond to the cell count of the 3D spheroid cell cultures.

Discover the capabilities of Amira Software. Transforming image data into interactive 3D models, aiding anatomical biology. Navigate high-resolution imaging from MRI, CT, light microscopy, and electron microscopy.
Amira-Software-bone-separation_1160x600_image-card
Courtesy of National Laboratory Animal Center - National Applied Research Laboratories, Taiwan.
Amira-Software-coregistration_1160x600_image-card

Co-registration for distribution studies. CT/SPECT data courtesy of Dr. Nabil Boutagy of the Yale Translation Research Imaging Center.

Amira-Software-Preclinical_1160x600_image-card

Maximum intensity projection and surface reconstruction of a mouse thorax. Acquisition device: VAMP TomoScope® 30s+, Amira Software - Courtesy of Dr. Elizatea Stepina and Dr. Peter Hauff, Bayer Healthcare.

 

Features

 

画像データのインポートおよび処理

    • あらゆる規模、あらゆるサイズのモダリティを処理

    - バイオフォーマット
    - ビットマップフォーマット
    - 顕微鏡:電子および光学
    - 医学および神経画像フォーマット
    - 分子フォーマット
    - その他の画像取得機器(MRI、X線など)

    • 有限要素モデリング、幾何モデリング、CAD
    • マルチデータ/マルチビュー、マルチチャンネル、時系列、非常に大きなデータのサポート
    • 倍率、校正、変換、試料の再採取
    • 画像補正、広範囲フィルタリングおよび畳み込み、周波数フーリエ変換
    • アーティファクト低減アルゴリズム
    • 高度なマルチモード2D/3D自動登録
    • 画像スタックアライメント、演算、相関、統合

    画像データの容易なセグメンテーション

    • 閾値化および自動セグメンテーション、物体の分離、自動ラベリング
    • 領域拡張法、スネーク法、内挿、ラッピング、平滑化
    • Watershedアルゴリズムやbasinアルゴリズムなどの形態学的処理
    • 機械学習に基づくセグメンテーション
    • 個々の繊維、フィラメントの自動トレース
    • 細線化およびフィラメントネットワーク抽出
    • セグメンテーションまたは空間グラフの生成と編集のためのインタラクティブツール
    • 3D表面再構成
    • FEA/CFD のグリッド生成

     

    分析および視覚化の成果をエクスポートしてシームレスに公開および発表

    • アニメーションおよび動画の作成
    • 高度なキーフレームとオブジェクトアニメーション
    • 画像、幾何学的モデル、測定値、シミュレーションをミックス
    • 注釈、測定の凡例、ヒストグラム、曲線プロット
    • スプレッドシート、3Dモデル、高品質の画像をエクスポート
    • 能動的および受動的3次元ステレオビジョン
    • 単一またはタイルドスクリーンディスプレイ
    • 没入環境

    画像データの可視化と探索

    • インタラクティブな高品質ボリュームおよびマルチチャンネルの可視化
    • 直角、傾斜、円柱状、曲線状の切断
    • 輪郭およびアイソサーフェス抽出
    • 最大値投影法または他の種類の投影法
    • ベクトルおよびテンソルの可視化
    • 物体および追跡
    • 分子可視化

    画像データの解析と定量情報の取得

    • 直感的なレシピの作成、カスタマイズ、自動再実行
    • カウント、容積、面積、周囲長、アスペクト比、方向などの測定機能を搭載
    • ユーザー定義の方法
    • スプレッドシートツールおよび図表による結果表示
    • 個々の機能の自動測定、3Dローカリゼーション、スプレッドシート選択
    • 自動統計、分布図
    • 任意の測定基準を使用した特徴フィルタリング
    • データ登録、変形、比較および測定

     

    ユーザーニーズに合わせた、Amiraソフトウェアの容易かつ迅速な適応

    • カスタムC++モジュールの開発
    • MATLAB™ブリッジ
    • PythonスクリプトAPI

    Contact us

    For Research Use Only. Not for use in diagnostic procedures.

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