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Key applications

  • ChIP sequencing
  • Exome sequencing
  • Gene expression sequencing
  • De novo sequencing
  • Small RNA sequencing
  • Whole transcriptome sequencing

Areas of interest

  • Agricultural research
  • Stem cell research
  • Cancer research
  • Epigenomics
  • Ancient DNA genomics
  • Metagenomics

Chip compatibility

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Ion PI v3 Chip

60–80M reads
~2.5 hours run time

Ion Proton System performance specifications with Ion PI Chip

ThroughputUp to 15 Gb
Read lengthUp to 200-base fragment reads
Number of reads passing filter60-80 million reads passing filter
Sequencing run time2.5 hours
Barcoding solutions384 barcodes supported by Torrent Suite Software
96 off-the-shelf barcodes for DNA
16 off-the-shelf barcodes for RNA
Software solutions

Torrent Suite Software utilizing Torrent Browser including TMAP alignment and Torrent Variant Caller for germline or somatic mutation detection.

Torrent Browser (included) offers users remote web access to instrument status monitoring, run quality reports, individual data files, and extensible plug-ins for application-specific analysis.

Plugins available for download from the Torrent Browser Plugin Store for analysis of genome sequencing, targeted sequencing, variant analysis and annotation, microbial sequencing, transfer to 3rd party bioinformatics packages, and more.

Data can optionally flow into Ion Reporter Software for controlled analysis, annotation, and reporting of variants. Ion Reporter Software provides application specific workflows to support single, trio and paired tumor normal analysis.

Data formatsIndustry standard FASTQ, SFF, BAM and VCF format outputs

Specifications for the Ion Proton Sequencer

Working environment (for indoor use only)Temperature: 68-77° F (20-25° C)
Humidity: 40-60%, noncondensing
Altitude: <6,500 ft (2,000 m)
Clearances:
12 in (30.5 cm) in rear
4 in (10 cm) on left side
4 in (10cm) on right side
4 in (10 cm) from front edge of bench to sequencer bezel
36 in (90 cm) aisle in front of bench for operator access
Optional rack mounting with two Ion Proton Sequencers per rack
Gas SupplyConnection: 0.25 in push-to-connect fitting
Pressure: 30 psi
Composition: nitrogen (grade 4.8, 99.998% or better)
Other connectionsEthernet: 1 GigE
USB: 2x USB 2.0
PowerVoltage: 100 V (min) to 240 V (max)
Current: 14 A (max)
Frequencing: 50/60 Hz
Power Draw: 1,350 W
DimensionsWidth: 21.3 in/54.2 cm
Depth: 30.5 in/77.5 cm
Height: 18.7in/47.4 cm
WeightCrated for shipment: 200 lb/90.7 kg
Free-standing: 130 lb/59 kg

†Space-saving rack can be purchased for the Ion Proton System. Contact your sales representative for details.

The trademarks mentioned herein are the property of Thermo Fisher Scientific Inc. and/or its affiliate(s) or their respective owners. Intel and Xeon are registered trademarks of Intel Corporation. NVIDIA and Tesla are registered trademarks of NVIDIA Corporation. Altera and Stratix are registered trademarks of of Altera Corporation. Ubuntu is a registered trademark of Canonical Ltd.


Service and support

Our service plans help keep you up and running. With service and support that spans the sequencing workflow from sample prep through validation, our service plans give you peace of mind wherever your research takes you.

  •  Professional installation
  •  Premium training package conducted by field scientists
  •  Worldwide application, technical, and field-training support
FeaturesAB CompleteAB AssuranceAB Maintenance
Repair response time (days)Guaranteed next day on-site repairs‡Guaranteed 2-day on-site repairs‡Target 2-day remedial repairs‡
Remote instrument monitoring and diagnostics

 
Priority phone and email access to instrument support

Instrument operation software upgrades

  
Instrument qualification services

  
Planned maintenance

Parts, labor and travelIncludedIncludedDiscount with Plus plan

‡Availability limited in some geographic areas

We also offer bioinformatics services to help you harness the power of Ion Torrent technology. 

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The trademarks mentioned herein are the property of Thermo Fisher Scientific Inc. and/or its affiliate(s) or their respective owners. Intel and Xeon are registered trademarks of Intel Corporation. NVIDIA and Tesla are registered trademarks of NVIDIA Corporation. Altera and Stratix are registered trademarks of of Altera Corporation. Ubuntu is a registered trademark of Canonical Ltd.

For Research Use Only. Not for use in diagnostic procedures.