Product References
XIAP promotes the expansion and limits the contraction of CD8 T cell response through cell extrinsic and intrinsic mechanisms respectively.
PLoS pathogens
Thakker P,Ariana A,Hajjar S,Cai D,Rijal D,Sad S
11-5931-82 was used in Flow cytometry/Cell sorting to reveal the temporal impact of XIAP in promoting the fitness of activated CD8 T cells through cell extrinsic and intrinsic mechanisms and provide a mechanistic explanation of the phenotype observed in XLP-2 patients.
Thu Jun 01 00:00:00 EDT 2023
Single-cell sequencing reveals homogeneity and heterogeneity of the cytopathological mechanisms in different etiology-induced AKI.
Cell death & disease
Chen Z,Li Y,Yuan Y,Lai K,Ye K,Lin Y,Lan R,Chen H,Xu Y
11-5931-82 was used in Flow Cytometry to provide a potent resource for understanding the pathogenesis of acute kidney injury AKI and early intervention in AKI progression at single-cell resolution.
Thu May 11 00:00:00 EDT 2023
Hypoxia-inducible factor 1A inhibition overcomes castration resistance of prostate tumors.
EMBO molecular medicine
Terzic J,Abu El Maaty MA,Lutzing R,Vincent A,El Bizri R,Jung M,Keime C,Metzger D
11-5931-82 was used in Flow cytometry/Cell sorting to demonstrate that HIF1A in prostatic tumor cells is a critical factor that enables their survival after ADT, and identify it as a target for CRPC management.
Wed Jun 07 00:00:00 EDT 2023
Foxo3a tempers excessive glutaminolysis in activated T cells to prevent fatal gut inflammation in the murine IL-10-/- model of colitis.
Cell death and differentiation
Hajjar S,Nathan N,Joseph J,Mottawea W,Ariana A,Pyatibrat S,Harper ME,Alain T,Blais A,Russell RC,Sad S
11-5931-82 was used in Flow cytometry/Cell sorting to show that Foxo3a restricts the abundance of colitogenic microbiota in IL-10-deficient mice.
Tue Mar 01 00:00:00 EST 2022
Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling.
Nature communications
Xie F,Zhou X,Su P,Li H,Tu Y,Du J,Pan C,Wei X,Zheng M,Jin K,Miao L,Wang C,Meng X,van Dam H,Ten Dijke P,Zhang L,Zhou F
11-5931-82 was used in Flow Cytometry to investigate TβRII and extracellular vesicle delivery in breast cancer to derive targets for immunotherapy.
Mon Aug 01 00:00:00 EDT 2022
Hypoxia-mediated stabilization of HIF1A in prostatic intraepithelial neoplasia promotes cell plasticity and malignant progression.
Science advances
Abu El Maaty MA,Terzic J,Keime C,Rovito D,Lutzing R,Yanushko D,Parisotto M,Grelet E,Namer IJ,Lindner V,Laverny G,Metzger D
11-5931-82 was used in Flow cytometry/Cell sorting to characterize prostatic intraepithelial neoplasia (PIN) progression and demonstrate that HIF1A is a target for PCa prevention and that TGM2 is a promising prognostic biomarker of early relapse after prostatectomy.
Fri Jul 22 00:00:00 EDT 2022
A Small Molecule Selected from a DNA-Encoded Library of Natural Products That Binds to TNF-α and Attenuates Inflammation In Vivo.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Wang S,Shi X,Li J,Huang Q,Ji Q,Yao Y,Wang T,Liu L,Ye M,Deng Y,Ma P,Xu H,Yang G
11-5931-82 was used in Flow cytometry/Cell sorting to identify small molecules that interfere with the protein-protein interaction between TNF-α and the cognate receptor.
Fri Jul 01 00:00:00 EDT 2022
GSDMD-dependent neutrophil extracellular traps promote macrophage-to-myofibroblast transition and renal fibrosis in obstructive nephropathy.
Cell death & disease
Wang Y,Li Y,Chen Z,Yuan Y,Su Q,Ye K,Chen C,Li G,Song Y,Chen H,Xu Y
11-5931-82 was used in Flow cytometry/Cell sorting to investigate the underlying molecular mechanism behind the promotion of renal fibrosis by inflammatory cells.
Mon Aug 08 00:00:00 EDT 2022
Characterization of the spectrum of trivalent VAV1-mutation-driven tumours using a gene-edited mouse model.
Molecular oncology
Robles-Valero J,Fernández-Nevado L,Cuadrado M,Lorenzo-Martín LF,Fernández-Pisonero I,Abad A,Redín E,Montuenga L,Martín-Zanca D,Bigas A,Mallo M,Dosil M,Bustelo XR
11-5931-82 was used in Flow cytometry/Cell sorting to indicate that VAV1 mutations play critical, although highly cell-type-specific, roles in tumourigenesis.
Sat Oct 01 00:00:00 EDT 2022
Nonredundancy of IL-1α and IL-1β is defined by distinct regulation of tissues orchestrating resistance versus tolerance to infection.
Science advances
Eislmayr K,Bestehorn A,Morelli L,Borroni M,Vande Walle L,Lamkanfi M,Kovarik P
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunohistochemistry
Fri Mar 04 00:00:00 EST 2022
Skin inflammation activates intestinal stromal fibroblasts and promotes colitis.
The Journal of clinical investigation
Dokoshi T,Seidman JS,Cavagnero KJ,Li F,Liggins MC,Taylor BC,Olvera J,Knight R,Chang JT,Salzman NH,Gallo RL
11-5931-82 was used in Flow Cytometry to understand whether fibroblasts participate in the pathogenesis of inflammatory bowel diseases and if hyaluronan could act as a signal from the skin to alter intestinal immune function through effects on fat cell differentiation.
Mon Nov 01 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
RIPK3 Facilitates Host Resistance to Oral Toxoplasma gondii Infection.
Infection and immunity
Cervantes PW,Martorelli Di Genova B,Erazo Flores BJ,Knoll LJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunohistochemistry
Fri Apr 16 00:00:00 EDT 2021
BRD4-mediated repression of p53 is a target for combination therapy in AML.
Nature communications
Latif AL,Newcombe A,Li S,Gilroy K,Robertson NA,Lei X,Stewart HJS,Cole J,Terradas MT,Rishi L,McGarry L,McKeeve C,Reid C,Clark W,Campos J,Kirschner K,Davis A,Lopez J,Sakamaki JI,Morton JP,Ryan KM,Tait SWG,Abraham SA,Holyoake T,Higgins B,Huang X,Blyth K,Copland M,Chevassut TJT,Keeshan K,Adams PD
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Mon Jan 11 00:00:00 EST 2021
Design, Synthesis and Biological Evaluation of Arylpyridin-2-yl Guanidine Derivatives and Cyclic Mimetics as Novel MSK1 Inhibitors. An Application in an Asthma Model.
Molecules (Basel, Switzerland)
Bollenbach M,Nemska S,Wagner P,Camelin G,Daubeuf F,Obrecht A,Villa P,Rognan D,Bihel F,Bourguignon JJ,Schmitt M,Frossard N
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Wed Jan 13 00:00:00 EST 2021
IFNγ-Producing γ/δ T Cells Accumulate in the Fetal Brain Following Intrauterine Inflammation.
Frontiers in immunology
Lewis EL,Tulina N,Anton L,Brown AG,Porrett PM,Elovitz MA
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Wed Jan 05 00:00:00 EST 2022
Lung mesenchymal stromal cells influenced by Th2 cytokines mobilize neutrophils and facilitate metastasis by producing complement C3.
Nature communications
Zheng Z,Li YN,Jia S,Zhu M,Cao L,Tao M,Jiang J,Zhan S,Chen Y,Gao PJ,Hu W,Wang Y,Shao C,Shi Y
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Wed Oct 27 00:00:00 EDT 2021
Retinoic Acid Inhibits Tumor-Associated Mesenchymal Stromal Cell Transformation in Melanoma.
Frontiers in cell and developmental biology
Lou Q,Zhao M,Xu Q,Xie S,Liang Y,Chen J,Yuan L,Wang L,Jiang L,Mou L,Lin D,Zhao M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Sat Apr 24 00:00:00 EDT 2021
Comprehensive mutagenesis identifies the peptide repertoire of a p53 T-cell receptor mimic antibody that displays no toxicity in mice transgenic for human HLA-A*0201.
PloS one
Trenevska I,Anderson AP,Bentley C,Hassanali T,Wiblin S,Maguire S,Pezzella F,Banham AH,Li D
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Wed Sep 29 00:00:00 EDT 2021
STING activation in alveolar macrophages and group 2 innate lymphoid cells suppresses IL-33-driven type 2 immunopathology.
JCI insight
She L,Barrera GD,Yan L,Alanazi HH,Brooks EG,Dube PH,Sun Y,Zan H,Chupp DP,Zhang N,Zhang X,Liu Y,Li XD
11-5931-82 was used in Flow cytometry/Cell sorting to suggest that STING activation by 2'3'-cGAMP in alveolar macrophages and ILC2 cells can negatively regulate type 2 immune responses, implying that the respiratory delivery of 2'3'-cGAMP might be further developed as an alternative strategy for treating type 2 immunopathologic diseases such as eosinophilic asthma.
Mon Feb 08 00:00:00 EST 2021
Abraxane-induced bone marrow CD11b+ myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with 64Cu-labeled anti-CD11b and prevented by anti-CSF-1.
Theranostics
Cao Q,Huang Q,Wang YA,Li C
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Fri Jul 23 00:00:00 EDT 2021
SPARC regulation of PMN clearance protects from pristane-induced lupus and rheumatoid arthritis.
iScience
Sangaletti S,Botti L,Gulino A,Lecis D,Bassani B,Portararo P,Milani M,Cancila V,De Cecco L,Dugo M,Tripodo C,Colombo MP
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunohistochemistry
Fri Jun 25 00:00:00 EDT 2021
Encapsulation of murine hematopoietic stem and progenitor cells in a thiol-crosslinked maleimide-functionalized gelatin hydrogel.
Acta biomaterialia
Gilchrist AE,Serrano JF,Ngo MT,Hrnjak Z,Kim S,Harley BAC
11-5931-82 was used in flow cytometry to report inclusion of a peptide crosslinker that can be cleaved via the proteolytic action of Sortase A and show that Sortase A exposure does not degrade sensitive surface marker expression patterns.
Wed Sep 01 00:00:00 EDT 2021
Shikonin ameliorates lipoteichoic acid‑induced acute lung injury via promotion of neutrophil apoptosis.
Molecular medicine reports
Zhang Y,Zhang H,Wang M,Gao S,Hong L,Hou T,Zhang Y,Zhu Y,Qian F
11-5931-82 was used in Flow cytometry/Cell sorting to demonstrate that shikonin protects against LTA‚induced ALI by promoting caspase-3 and Mcl‚1‚related neutrophil apoptosis, suggesting that shikonin is a potential agent that can be used in the treatment of sepsis‚mediated lung injury.
Mon Feb 01 00:00:00 EST 2021
Single-cell analyses unravel cell type-specific responses to a vitamin D analog in prostatic precancerous lesions.
Science advances
Abu El Maaty MA,Grelet E,Keime C,Rerra AI,Gantzer J,Emprou C,Terzic J,Lutzing R,Bornert JM,Laverny G,Metzger D
11-5931-82 was used in Flow Cytometry to determine the impact of vitamin D signaling on prostatic precancerous lesions.
Thu Jul 01 00:00:00 EDT 2021
Single-cell analyses unravel cell type-specific responses to a vitamin D analog in prostatic precancerous lesions.
Science advances
Abu El Maaty MA,Grelet E,Keime C,Rerra AI,Gantzer J,Emprou C,Terzic J,Lutzing R,Bornert JM,Laverny G,Metzger D
11-5931-82 was used in Flow Cytometry to determine the impact of vitamin D signaling on prostatic precancerous lesions.
Thu Jul 01 00:00:00 EDT 2021
Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms.
Nature communications
Shi X,Wan Y,Wang N,Xiang J,Wang T,Yang X,Wang J,Dong X,Dong L,Yan L,Li Y,Liu L,Hou S,Zhong Z,Wilson IA,Yang B,Yang G,Lerner RA
11-5931-82 was used in Flow cytometry/Cell sorting to describe an epitope-guided approach for selection of antibodies that modulate cellular signaling of targeted receptors.
Wed May 05 00:00:00 EDT 2021
Construction, characterization, and immunization of nanoparticles that display a diverse array of influenza HA trimers.
PloS one
Cohen AA,Yang Z,Gnanapragasam PNP,Ou S,Dam KA,Wang H,Bjorkman PJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Fri Oct 15 00:00:00 EDT 2021
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist.
eLife
Glassman CR,Su L,Majri-Morrison SS,Winkelmann H,Mo F,Li P,Pérez-Cruz M,Ho PP,Koliesnik I,Nagy N,Hnizdilova T,Picton LK,Kovar M,Bollyky P,Steinman L,Meyer E,Piehler J,Leonard WJ,Garcia KC
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Tue May 18 00:00:00 EDT 2021
Myocardial infarction accelerates breast cancer via innate immune reprogramming.
Nature medicine
Koelwyn GJ,Newman AAC,Afonso MS,van Solingen C,Corr EM,Brown EJ,Albers KB,Yamaguchi N,Narke D,Schlegel M,Sharma M,Shanley LC,Barrett TJ,Rahman K,Mezzano V,Fisher EA,Park DS,Newman JD,Quail DF,Nelson ER,Caan BJ,Jones LW,Moore KJ
11-5931 was used in Flow cytometry/Cell sorting to show that myocardial infarction (MI) accelerates breast cancer outgrowth and cancer-specific mortality in mice and humans. I.
Tue Sep 01 00:00:00 EDT 2020
Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis.
Immunity
Tummers B,Mari L,Guy CS,Heckmann BL,Rodriguez DA,Rühl S,Moretti J,Crawford JC,Fitzgerald P,Kanneganti TD,Janke LJ,Pelletier S,Blander JM,Green DR
11-5931-82 was used in Immunohistochemistry to suggest an in vivo role of the inflammatory RIPK1-caspase-8-FADD (FADDosome) complex and reveal a FADD-independent inflammatory role of caspase-8 that involves activation of an inflammasome.
Tue Jun 16 00:00:00 EDT 2020
Salmonella-Driven Polarization of Granuloma Macrophages Antagonizes TNF-Mediated Pathogen Restriction during Persistent Infection.
Cell host & microbe
Pham THM,Brewer SM,Thurston T,Massis LM,Honeycutt J,Lugo K,Jacobson AR,Vilches-Moure JG,Hamblin M,Helaine S,Monack DM
11-5931 was used in Flow cytometry/Cell sorting to elucidate a host-pathogen interaction that controls granuloma macrophage polarization and long-term pathogen persistence during Salmonella Typhimurium (STm) infection.
Wed Jan 08 00:00:00 EST 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia.
Proceedings of the National Academy of Sciences of the United States of America
Kitchen GB,Cunningham PS,Poolman TM,Iqbal M,Maidstone R,Baxter M,Bagnall J,Begley N,Saer B,Hussell T,Matthews LC,Dockrell DH,Durrington HJ,Gibbs JE,Blaikley JF,Loudon AS,Ray DW
11-5931-82 was used in Flow Cytometry to show that loss of the core clock protein BMAL1 in macrophages confers protection against pneumococcal pneumonia.
Tue Jan 21 00:00:00 EST 2020
The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia.
Proceedings of the National Academy of Sciences of the United States of America
Kitchen GB,Cunningham PS,Poolman TM,Iqbal M,Maidstone R,Baxter M,Bagnall J,Begley N,Saer B,Hussell T,Matthews LC,Dockrell DH,Durrington HJ,Gibbs JE,Blaikley JF,Loudon AS,Ray DW
11-5931-82 was used in Flow Cytometry to show that loss of the core clock protein BMAL1 in macrophages confers protection against pneumococcal pneumonia.
Tue Jan 21 00:00:00 EST 2020
RIPK3 collaborates with GSDMD to drive tissue injury in lethal polymicrobial sepsis.
Cell death and differentiation
Chen H,Li Y,Wu J,Li G,Tao X,Lai K,Yuan Y,Zhang X,Zou Z,Xu Y
11-5931-82 was used in Flow Cytometry to demonstrate that RIPK3-mediated necroptosis and GSDMD-mediated pyroptosis collaborated to amply inflammatory signaling and enhance tissue injury in the process of sepsis, which may shed new light on two potential targets of combined therapeutic interventions for this highly lethal disorder.
Tue Sep 01 00:00:00 EDT 2020
Ku80-Targeted pH-Sensitive Peptide-PNA Conjugates Are Tumor Selective and Sensitize Cancer Cells to Ionizing Radiation.
Molecular cancer research : MCR
Kaplan AR,Pham H,Liu Y,Oyaghire S,Bahal R,Engelman DM,Glazer PM
11-5931 was used in Flow cytometry/Cell sorting to describes a novel agent, pHLIP-αKu80(γ), which combines PNA antisense and pHLIP technologies to selectively reduce the expression of the DNA repair factor KU80 in tumors and confer tumor-selective radiosensitization.
Mon Jun 01 00:00:00 EDT 2020
In Situ Therapeutic Cancer Vaccination with an Oncolytic Virus Expressing Membrane-Tethered IL-2.
Molecular therapy oncolytics
Liu W,Dai E,Liu Z,Ma C,Guo ZS,Bartlett DL
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Fri Jun 26 00:00:00 EDT 2020
Deficiency of immunoglobulin E protects mice from experimental abdominal aortic aneurysms.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Li J,Deng Z,Zhang X,Liu F,Yang C,Shi GP
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
Methylprednisolone alleviates multiple sclerosis by expanding myeloid-derived suppressor cells via glucocorticoid receptor β and S100A8/9 up-regulation.
Journal of cellular and molecular medicine
Wang Z,Zheng G,Li G,Wang M,Ma Z,Li H,Wang XY,Yi H
11-5931 was used in Flow cytometry/Cell sorting to suggest that GCs treatment may help relieve the acute phase of MS by expanding MDSC through up-regulating of GR signalling and S100A8/A9 heterodimers.
Tue Dec 01 00:00:00 EST 2020
Development of an inexpensive Raman-compatible substrate for the construction of a microarray screening platform.
The Analyst
Pastrana-Otero I,Majumdar S,Gilchrist AE,Gorman BL,Harley BAC,Kraft ML
11-5931-82 was used in Flow Cytometry to show that the spectra acquired from individual living cells on functionalized PA gels attached to our custom substrates were of sufficient quality to enable accurate identification of cell phenotypes using PLS-DA models of the cell spectra.
Mon Oct 26 00:00:00 EDT 2020
HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment.
Journal of Cancer
Kim YD,Park SM,Ha HC,Lee AR,Won H,Cha H,Cho S,Cho JM
11-5931 was used in Flow cytometry/Cell sorting to study the HDAC inhibitor CG-745 and its function to enable the synergistic effects of the immune checkpoint inhibitor combination therapy in various cancers by suppressing tumor microenvironment.
Mon Sep 28 00:00:00 EDT 2020
Flagellin-Stimulated Production of Interferon-β Promotes Anti-Flagellin IgG2c and IgA Responses.
Molecules and cells
Kang W,Park A,Huh JW,You G,Jung DJ,Song M,Lee HK,Kim YM
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Tue Mar 31 00:00:00 EDT 2020
Immunotherapy of Bacillus Calmette‑Guérin by targeting macrophages against bladder cancer in a NOD/scid IL2Rg‑/‑ mouse model.
Molecular medicine reports
Tan QL,Zhou CY,Cheng L,Luo M,Liu CP,Xu WX,Zhang X,Zeng X
11-5931 was used in Flow cytometry/Cell sorting to investigate the role and potential mechanism of Bacillus Calmette-Guérin (BCG) immunotherapy for bladder cancer (BCa).
Wed Jul 01 00:00:00 EDT 2020
Effects of Hypertonic Saline and Hydroxyethyl Starch on Myeloid-Derived Suppressor Cells in Hemorrhagic Shock Mice under Secondary Bacterial Attack.
BioMed research international
Jiang JK,Hong LJ,Lu YQ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
Connecting secretome to hematopoietic stem cell phenotype shifts in an engineered bone marrow niche.
Integrative biology : quantitative biosciences from nano to macro
Gilchrist AE,Harley BAC
11-5931-82 was used in Flow Cytometry to investigate the mechanism of how marrow-derived mesenchymal stromal and progenitor cells impacts hematopoietic stem cells fate decisions.
Fri Jul 10 00:00:00 EDT 2020
Long Non-Coding RNA Hotairm1 Promotes S100A9 Support of MDSC Expansion during Sepsis.
Journal of clinical & cellular immunology
Alkhateeb T,Bah I,Kumbhare A,Youssef D,Yao ZQ,McCall CE,Gazzar ME
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Sat Aug 13 00:00:00 EDT 2022
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection.
Cell reports
Dokoshi T,Zhang LJ,Li F,Nakatsuji T,Butcher A,Yoshida H,Shimoda M,Okada Y,Gallo RL
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Tue Jan 07 00:00:00 EST 2020
Loss of testosterone impairs anti-tumor neutrophil function.
Nature communications
Markman JL,Porritt RA,Wakita D,Lane ME,Martinon D,Noval Rivas M,Luu M,Posadas EM,Crother TR,Arditi M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Tue Mar 31 00:00:00 EDT 2020
Bacterial and Fungal Toll-Like Receptor Activation Elicits Type I IFN Responses in Mast Cells.
Frontiers in immunology
Kornstädt L,Pierre S,Weigert A,Ebersberger S,Schäufele TJ,Kolbinger A,Schmid T,Cohnen J,Thomas D,Ferreirós N,Brüne B,Ebersberger I,Scholich K
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Mon Jun 21 00:00:00 EDT 2021
Bacterial and Fungal Toll-Like Receptor Activation Elicits Type I IFN Responses in Mast Cells.
Frontiers in immunology
Kornstädt L,Pierre S,Weigert A,Ebersberger S,Schäufele TJ,Kolbinger A,Schmid T,Cohnen J,Thomas D,Ferreirós N,Brüne B,Ebersberger I,Scholich K
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Mon Jun 21 00:00:00 EDT 2021
Sensing and signaling of immunogenic extracellular RNAs restrain group 2 innate lymphoid cell-driven acute lung inflammation and airway hyperresponsiveness.
PloS one
She L,Alanazi HH,Yan L,Brooks EG,Dube PH,Xiang Y,Zhang F,Sun Y,Liu Y,Zhang X,Li XD
11-5931 was used in Flow cytometry/Cell sorting to demonstrate that the host detection of extracellular immunostimulatory RNAs generated during respiratory viral infections have an important function in the regulation of ILC2-driven acute lung inflammation.
Thu Sep 24 00:00:00 EDT 2020
Sensing and signaling of immunogenic extracellular RNAs restrain group 2 innate lymphoid cell-driven acute lung inflammation and airway hyperresponsiveness.
PloS one
She L,Alanazi HH,Yan L,Brooks EG,Dube PH,Xiang Y,Zhang F,Sun Y,Liu Y,Zhang X,Li XD
11-5931 was used in Flow cytometry/Cell sorting to demonstrate that the host detection of extracellular immunostimulatory RNAs generated during respiratory viral infections have an important function in the regulation of ILC2-driven acute lung inflammation.
Thu Sep 24 00:00:00 EDT 2020
Prevention of acute kidney injury by low intensity pulsed ultrasound via anti-inflammation and anti-apoptosis.
Scientific reports
Chiang CK,Loh JZ,Yang TH,Huang KT,Wu CT,Guan SS,Liu SH,Hung KY
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunohistochemistry
Mon Aug 31 00:00:00 EDT 2020
Prevention of acute kidney injury by low intensity pulsed ultrasound via anti-inflammation and anti-apoptosis.
Scientific reports
Chiang CK,Loh JZ,Yang TH,Huang KT,Wu CT,Guan SS,Liu SH,Hung KY
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunohistochemistry
Mon Aug 31 00:00:00 EDT 2020
Mesenchymal stem cells reduce alcoholic hepatitis in mice via suppression of hepatic neutrophil and macrophage infiltration, and of oxidative stress.
PloS one
Wan YM,Li ZQ,Liu C,He YF,Wang MJ,Wu XN,Zhang Y,Li YH
11-5931-82 was used in Flow Cytometry to investigate whether MSCs are effective in treating mice with alcoholic hepatitis (AH) and its underlying mechanism.
Thu May 07 00:00:00 EDT 2020
Protocol for Flow Cytometric Detection of Immune Cell Infiltration in the Epidermis and Dermis of a Psoriasis Mouse Model.
STAR protocols
Lou F,Sun Y,Wang H
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Fri Dec 18 00:00:00 EST 2020
ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms.
Cell reports
Viaud M,Abdel-Wahab O,Gall J,Ivanov S,Guinamard R,Sore S,Merlin J,Ayrault M,Guilbaud E,Jacquel A,Auberger P,Wang N,Levine RL,Tall AR,Yvan-Charvet L
11-5931 was used in Flow cytometry/Cell sorting to identify somatic mutations in ABCA1 that subvert its anti-proliferative and cholesterol efflux functions and permit the progression of myeloid neoplasms.
Tue Mar 10 00:00:00 EDT 2020
Use of Busulfan to Condition Mice for Bone Marrow Transplantation.
STAR protocols
Montecino-Rodriguez E,Dorshkind K
11-5931 was used in Flow cytometry/Cell sorting to describe a protocol for the use of busulfan to condition mice for bone marrow transplantation and several of the variables to consider for effective implementation.
Fri Dec 18 00:00:00 EST 2020
The endothelial protein C receptor plays an essential role in the maintenance of pregnancy.
Science advances
Castillo MM,Yang Q,Sigala AS,McKinney DT,Zhan M,Chen KL,Jarzembowski JA,Sood R
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunohistochemistry
Sun Nov 01 00:00:00 EDT 2020
Loss of FGFR3 Delays Acute Myeloid Leukemogenesis by Programming Weakly Pathogenic CD117-Positive Leukemia Stem-Like Cells.
Frontiers in pharmacology
Guo C,Ran Q,Sun C,Zhou T,Yang X,Zhang J,Pang S,Xiao Y
11-5931-82 was used in Flow Cytometry to find that FGFR3 had a novel regulatory mechanism for the stemness of LSCs in AML, and provided a promising anti-leukemia approach by interrupting FGFR3.
Tue Feb 16 00:00:00 EST 2021
Glucocorticoids Promote the Onset of Acute Experimental Colitis and Cancer by Upregulating mTOR Signaling in Intestinal Epithelial Cells.
Cancers
Zhang Z,Dong L,Jia A,Chen X,Yang Q,Wang Y,Wang Y,Liu R,Cao Y,He Y,Bi Y,Liu G
11-5931 was used in Flow cytometry/Cell sorting to indicate that glucocorticoid-induced mTOR signaling in epithelial cells is required in the early stages of acute ulcerative colitis by modulating the dynamics of innate immune cell recruitment and activation.
Sat Apr 11 00:00:00 EDT 2020
Renal proximal tubular NEMO plays a critical role in ischemic acute kidney injury.
JCI insight
Han SJ,Williams RM,Kim M,Heller DA,D'Agati V,Schmidt-Supprian M,Lee HT
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunohistochemistry
Thu Sep 17 00:00:00 EDT 2020
The Innate Immune Response to Infection Induces Erythropoietin-Dependent Replenishment of the Dendritic Cell Compartment.
Frontiers in immunology
Einwächter H,Heiseke A,Schlitzer A,Gasteiger G,Adler H,Voehringer D,Manz MG,Ruzsics Z,Dölken L,Koszinowski UH,Sparwasser T,Reindl W,Jordan S
11-5931-82 was used in Flow Cytometry to investigate the molecular and cellular mechanisms of inflammation-induced dendritic cell generation.
Mon Apr 19 00:00:00 EDT 2021
Distinct Waves from the Hemogenic Endothelium Give Rise to Layered Lymphoid Tissue Inducer Cell Ontogeny.
Cell reports
Simic M,Manosalva I,Spinelli L,Gentek R,Shayan RR,Siret C,Girard-Madoux M,Wang S,de Fabritus L,Verschoor J,Kerdiles YM,Bajenoff M,Stumm R,Golub R,van de Pavert SA
11-5931 was used in Flow cytometry/Cell sorting to identify a major contribution from embryonic hemogenic endothelium, but not the yolk sac, toward LTi progenitors.
Tue Aug 11 00:00:00 EDT 2020
Neutrophils contribute to spontaneous resolution of liver inflammation and fibrosis via microRNA-223.
The Journal of clinical investigation
Calvente CJ,Tameda M,Johnson CD,Del Pilar H,Lin YC,Adronikou N,De Mollerat Du Jeu X,Llorente C,Boyer J,Feldstein AE
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Thu Jul 11 00:00:00 EDT 2019
Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer.
The Journal of clinical investigation
Soukup AA,Zheng Y,Mehta C,Wu J,Liu P,Cao M,Hofmann I,Zhou Y,Zhang J,Johnson KD,Choi K,Keles S,Bresnick EH
11-5931 was used in Flow cytometry/Cell sorting to study the mechanisms underlying how GATA2 enhancer disease mutations impact hematopoiesis and pathology.
Fri Mar 01 00:00:00 EST 2019
Retinoblastoma Inactivation Induces a Protumoral Microenvironment via Enhanced CCL2 Secretion.
Cancer research
Li F,Kitajima S,Kohno S,Yoshida A,Tange S,Sasaki S,Okada N,Nishimoto Y,Muranaka H,Nagatani N,Suzuki M,Masuda S,Thai TC,Nishiuchi T,Tanaka T,Barbie DA,Mukaida N,Takahashi C
11-5931 was used in Flow cytometry/Cell sorting to show that inactivation of the tumour suppressor retinoblastoma leads to a protumoral microenvironment via an increase in the secretion of the chemoattractant CCL2.
Thu Aug 01 00:00:00 EDT 2019
Inhibition of phosphodiesterase-4 attenuates murine ulcerative colitis through interference with mucosal immunity.
British journal of pharmacology
Li H,Fan C,Feng C,Wu Y,Lu H,He P,Yang X,Zhu F,Qi Q,Gao Y,Zuo J,Tang W
11-5931 was used in Flow cytometry/Cell sorting to demonstrate that inhibition of PDE4 by apremilast protected against ulcerative colitis, by interfering with mucosal immunity in mice.
Mon Jul 01 00:00:00 EDT 2019
Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.
Anti-cancer drugs
Zhou Y,Fu C,Kong Y,Pan D,Wang Y,Huang S,Li Z,Ning Z,Lu X,Shan S,Xin L
11-5931 was used in Flow cytometry/Cell sorting to investigate the antitumor and immunomodulatory effects of CS2164.
Tue Oct 01 00:00:00 EDT 2019
Neutrophil extracellular traps induced by VP1 contribute to pulmonary edema during EV71 infection.
Cell death discovery
Wang N,Yang X,Sun J,Sun Z,Ma Q,Wang Z,Chen Z,Wang Z,Hu F,Wang H,Zhou L,Zhang M,Xu J
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Wed Sep 30 00:00:00 EDT 2020
Hemozoin produced by mammals confers heme tolerance.
eLife
Pek RH,Yuan X,Rietzschel N,Zhang J,Jackson L,Nishibori E,Ribeiro A,Simmons W,Jagadeesh J,Sugimoto H,Alam MZ,Garrett L,Haldar M,Ralle M,Phillips JD,Bodine DM,Hamza I
11-5931-82 was used in Flow Cytometry to show that mice deficient for the heme transporter SLC48A1 (also known as HRG1) accumulate over ten-fold excess heme in reticuloendothelial macrophage lysosomes that are 10 to 100 times larger than normal.
Tue Oct 01 00:00:00 EDT 2019
Critical Roles of E2F3 in Growth and Musculo-skeletal Phenotype in Mice.
International journal of medical sciences
Kim HR,Rahman FU,Kim KS,Kim EK,Cho SM,Lee K,Moon OS,Seo YW,Yoon WK,Won YS,Kang H,Kim HC,Nam KH
11-5931-82 was used in Flow Cytometry to suggest that E2F3 has a pivotal role in muscle and bone development, and affect normal mouse growth.
Thu Apr 30 00:00:00 EDT 2020
Deletion of C-C Motif Chemokine Ligand 5 Worsens Invariant Natural Killer T-Cell-Mediated Hepatitis via Compensatory Up-regulation of CXCR2-Related Chemokine Activity.
Cellular and molecular gastroenterology and hepatology
Chen L,Gu J,Qian Y,Li M,Qian Y,Xu M,Li J,Wen Y,Xia L,Li J,Xia Q,Kong X,Wu H
11-5931 was used in Flow cytometry/Cell sorting to demonstrate that the clinical use of blocking CCL5 may induce other chemokine signals such as CXCL1-CXCR2 to induce further enhanced hepatic infiltration of neutrophils.
Tue Jun 04 00:00:00 EDT 2019
The role of platelets in mediating a response to human influenza infection.
Nature communications
Koupenova M,Corkrey HA,Vitseva O,Manni G,Pang CJ,Clancy L,Yao C,Rade J,Levy D,Wang JP,Finberg RW,Kurt-Jones EA,Freedman JE
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunocytochemistry
Tue Apr 16 00:00:00 EDT 2019
Mouse models of Loa loa.
Nature communications
Pionnier NP,Sjoberg H,Chunda VC,Fombad FF,Chounna PW,Njouendou AJ,Metuge HM,Ndzeshang BL,Gandjui NV,Akumtoh DN,Tayong DB,Taylor MJ,Wanji S,Turner JD
11-5931 was used in Flow cytometry/Cell sorting to provide validation of murine research models to identify loiasis biomarkers, to counter-screen candidate river blindness cures and to interrogate the inflammatory etiology of loiasis ivermectin-associated adverse reactions.
Fri Mar 29 00:00:00 EDT 2019
Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy.
Cell reports
Hirukawa A,Singh S,Wang J,Rennhack JP,Swiatnicki M,Sanguin-Gendreau V,Zuo D,Daldoul K,Lavoie C,Park M,Andrechek ER,Westbrook TF,Harris LN,Varadan V,Smith HW,Muller WJ
11-5931-82 was used in Flow cytometry/Cell sorting to provide evidence that EZH2 inhibitors promote interferon-driven immune responses that enhance the efficacy of anti-ErbB2 mAbs, suggesting the potential clinical benefit of epigenomic reprogramming by H3K27me3 depletion in Trastuzumab-resistant disease.
Tue Oct 08 00:00:00 EDT 2019
E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.
Immunity
Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Tue Feb 20 00:00:00 EST 2018
Virus-Induced Interferon-γ Causes Insulin Resistance in Skeletal Muscle and Derails Glycemic Control in Obesity.
Immunity
Šestan M,Marinović S,Kavazović I,Cekinović Đ,Wueest S,Turk Wensveen T,Brizić I,Jonjić S,Konrad D,Wensveen FM,Polić B
11-5931 was used in Flow cytometry/Cell sorting to study how viral infection effects insulin resistance.
Tue Jul 17 00:00:00 EDT 2018
Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells.
Immunity
Hu G,Cui K,Fang D,Hirose S,Wang X,Wangsa D,Jin W,Ried T,Liu P,Zhu J,Rothenberg EV,Zhao K
11-5931 was used in Flow cytometry/Cell sorting to find that abrupt genome-wide changes at all three levels of chromatin organization occur during the transition from double-negative stage 2 (DN2) to DN3, accompanying the T lineage commitment.
Tue Feb 20 00:00:00 EST 2018
Non-classical monocytes as mediators of tissue destruction in arthritis.
Annals of the rheumatic diseases
Puchner A,Saferding V,Bonelli M,Mikami Y,Hofmann M,Brunner JS,Caldera M,Goncalves-Alves E,Binder NB,Fischer A,Simader E,Steiner CW,Leiss H,Hayer S,Niederreiter B,Karonitsch T,Koenders MI,Podesser BK,O'Shea JJ,Menche J,Smolen JS,Redlich K,Blüml S
11-5931 was used in Flow cytometry/Cell sorting to deduce that non-classical monocytes are pivotal cells in arthritis tissue damage.
Mon Oct 01 00:00:00 EDT 2018
CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine.
Cell stem cell
Hirata Y,Furuhashi K,Ishii H,Li HW,Pinho S,Ding L,Robson SC,Frenette PS,Fujisaki J
11-5931-82 was used in Immunohistochemistry (PFA fixed) to describe a Treg subpopulation that controls hematopoietic stem cell (HSC) quiescence and engraftment.
Thu Mar 01 00:00:00 EST 2018
Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment.
Cell stem cell
Yamamoto R,Wilkinson AC,Ooehara J,Lan X,Lai CY,Nakauchi Y,Pritchard JK,Nakauchi H
11-5931 was used in Flow cytometry/Cell sorting to determine the age-related functional changes to the haematopoietic stem cell compartment.
Thu Apr 05 00:00:00 EDT 2018
Detection of Subclinical Arthritis in Mice by a Thrombin Receptor-Derived Imaging Agent.
Arthritis & rheumatology (Hoboken, N.J.)
Friedman B,Whitney MA,Savariar EN,Caneda C,Steinbach P,Xiong Q,Hingorani DV,Crisp J,Adams SR,Kenner M,Lippert CN,Nguyen QT,Guma M,Tsien RY,Corr M
11-5931 was used in Immunohistochemistry-immunofluorescence to examine coagulation protease activities in arthritic mice with a dual-fluorescence ratiometric activatable cell-penetrating peptide that has a linker, norleucine-TPRSFL, with a cleavage site for thrombin.
Mon Jan 01 00:00:00 EST 2018
Hydrogen Sulfide Alleviates Acute Myocardial Ischemia Injury by Modulating Autophagy and Inflammation Response under Oxidative Stress.
Oxidative medicine and cellular longevity
Bai YD,Yang YR,Mu XP,Lin G,Wang YP,Jin S,Chen Y,Wang MJ,Zhu YC
11-5931-82 was used in Magnetic cell separation to investigate the influence of excessive oxidative stress on cardiac injury during acute myocardial ischemia.
Wed Dec 19 00:00:00 EST 2018
Frontline Science: Macrophage-derived exosomes promote neutrophil necroptosis following hemorrhagic shock.
Journal of leukocyte biology
Jiao Y,Li Z,Loughran PA,Fan EK,Scott MJ,Li Y,Billiar TR,Wilson MA,Shi X,Fan J
11-5931-82 was used in Flow Cytometry to explore a previously unidentified pathway of AMφ-PMN cross-talk, which causes enhanced PMN necroptosis and subsequent exaggerated post-HS lung inflammation.
Thu Feb 01 00:00:00 EST 2018
HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice.
Disease models & mechanisms
Kim YE,Lee M,Gu H,Kim J,Jeong S,Yeo S,Lee YJ,Im SH,Sung YC,Kim HJ,Weissman IL,Ahn GO
11-5931 was used in Flow cytometry/Cell sorting to study the role of hypoxia-inducible factor in the progression of inflammatory bowel disease.
Mon Jul 30 00:00:00 EDT 2018
Vitreous Cytokine Expression and a Murine Model Suggest a Key Role of Microglia in the Inflammatory Response to Retinal Detachment.
Investigative ophthalmology & visual science
Kiang L,Ross BX,Yao J,Shanmugam S,Andrews CA,Hansen S,Besirli CG,Zacks DN,Abcouwer SF
11-5931 was used in Flow cytometry/Cell sorting to examine the inflammatory responses to retinal detachment (RD) in patient vitreous and validate a mouse experimental RD as a model of this phenomenon.
Mon Jul 02 00:00:00 EDT 2018
Regulated Release of Cryptococcal Polysaccharide Drives Virulence and Suppresses Immune Cell Infiltration into the Central Nervous System.
Infection and immunity
Denham ST,Verma S,Reynolds RC,Worne CL,Daugherty JM,Lane TE,Brown JCS
11-5931 was used in Flow cytometry/Cell sorting to show that exo-glucuronoxylomannan (exo-GXM) performs a different role from capsule GXM during infection, altering cell size and suppressing inflammation.
Thu Mar 01 00:00:00 EST 2018
Antiasthmatic Effects of Sanglong Pingchuan Decoction through Inducing a Balanced Th1/Th2 Immune Response.
Evidence-based complementary and alternative medicine : eCAM
Zhu B,Dong J,Gao X,He Y,Sun H
11-5931 was used in Flow cytometry/Cell sorting to investigate the antiasthmatic effects of Sanglong pingchuan decoction and to explore its mechanisms of action.
Fri Mar 18 00:00:00 EDT 2022
Investigation of tumor-tumor interactions in a double human cervical carcinoma xenograft model in nude mice.
Oncotarget
Mertens B,Cristina de Araujo Nogueira T,Topalis D,Stranska R,Snoeck R,Andrei G
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Tue Apr 24 00:00:00 EDT 2018
Antiviral effects of ferric ammonium citrate.
Cell discovery
Wang H,Li Z,Niu J,Xu Y,Ma L,Lu A,Wang X,Qian Z,Huang Z,Jin X,Leng Q,Wang J,Zhong J,Sun B,Meng G
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2020
Induction of neutrophil apoptosis by a Bcl-2 inhibitor reduces particulate matter-induced lung inflammation.
Aging
Geng X,Wang X,Luo M,Xing M,Wu Y,Li W,Chen Z,Shen H,Ying S
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Tue Jun 26 00:00:00 EDT 2018
Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice.
mSphere
Quach D,Collins F,Parameswaran N,McCabe L,Britton RA
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Type 2 Innate Lymphocytes Actuate Immunity Against Tumours and Limit Cancer Metastasis.
Scientific reports
Saranchova I,Han J,Zaman R,Arora H,Huang H,Fenninger F,Choi KB,Munro L,Pfeifer CG,Welch I,Takei F,Jefferies WA
11-5931 was used in Flow cytometry/Cell sorting to study the role of type 2 innate lymphoid cells in enhancing anti-cancer immunity and controlling metastasis.
Tue Feb 13 00:00:00 EST 2018
Hyaluronidase inhibits reactive adipogenesis and inflammation of colon and skin.
JCI insight
Dokoshi T,Zhang LJ,Nakatsuji T,Adase CA,Sanford JA,Paladini RD,Tanaka H,Fujiya M,Gallo RL
Fri Nov 02 00:00:00 EDT 2018
Targeting of the Yersinia pestis F1 capsular antigen by innate-like B1b cells mediates a rapid protective response against bubonic plague.
NPJ vaccines
Levy Y,Vagima Y,Tidhar A,Aftalion M,Gur D,Nili U,Chitlaru T,Zauberman A,Mamroud E
11-5931 was used in Flow cytometry/Cell sorting to shed new light on the potential of novel as well as well-known protective antigens in generating rapid immunity and could be implemented in the rational design of future vaccines.
Thu Oct 01 00:00:00 EDT 2020
Group 2 innate lymphoid cells protect lung endothelial cells from pyroptosis in sepsis.
Cell death & disease
Lai D,Tang J,Chen L,Fan EK,Scott MJ,Li Y,Billiar TR,Wilson MA,Fang X,Shu Q,Fan J
Tue Mar 06 00:00:00 EST 2018
Analysis of leukocyte transepithelial migration using an in vivo murine colonic loop model.
JCI insight
Flemming S,Luissint AC,Nusrat A,Parkos CA
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunofluorescence
Thu Oct 18 00:00:00 EDT 2018
In utero nanoparticle delivery for site-specific genome editing.
Nature communications
Ricciardi AS,Bahal R,Farrelly JS,Quijano E,Bianchi AH,Luks VL,Putman R,López-Giráldez F,Coşkun S,Song E,Liu Y,Hsieh WC,Ly DH,Stitelman DH,Glazer PM,Saltzman WM
11-5931 was used in Flow cytometry/Cell sorting to demonstrate the safe intravenous and intra-amniotic administration of polymeric nanoparticles to foetal mouse tissues at selected gestational ages with no effect on survival or postnatal growth.
Tue Jun 26 00:00:00 EDT 2018
Integrin CD11b activation drives anti-tumor innate immunity.
Nature communications
Schmid MC,Khan SQ,Kaneda MM,Pathria P,Shepard R,Louis TL,Anand S,Woo G,Leem C,Faridi MH,Geraghty T,Rajagopalan A,Gupta S,Ahmed M,Vazquez-Padron RI,Cheresh DA,Gupta V,Varner JA
11-5931 was used in Flow cytometry/Cell sorting to identify CD11b as a negative regulator of immune suppression and a target for cancer immune therapy.
Wed Dec 19 00:00:00 EST 2018
Characterization of Multiple Cytokine Combinations and TGF-β on Differentiation and Functions of Myeloid-Derived Suppressor Cells.
International journal of molecular sciences
Lee CR,Lee W,Cho SK,Park SG
11-5931 was used in Flow cytometry/Cell sorting to examine the effect of various cytokine combinations with transforming growth factor-β on myeloid-derived suppressor cells derived from bone marrow cells.
Thu Mar 15 00:00:00 EDT 2018
Helminth-induced IL-4 expands bystander memory CD8+ T cells for early control of viral infection.
Nature communications
Rolot M,Dougall AM,Chetty A,Javaux J,Chen T,Xiao X,Machiels B,Selkirk ME,Maizels RM,Hokke C,Denis O,Brombacher F,Vanderplasschen A,Gillet L,Horsnell WGC,Dewals BG
11-5931 was used in Flow cytometry/Cell sorting to study whether helminth-induced type 2 immunity functionally affects the T virtual memory cell compartment.
Tue Oct 30 00:00:00 EDT 2018
Estriol Reduces Pulmonary Immune Cell Recruitment and Inflammation to Protect Female Mice From Severe Influenza.
Endocrinology
Vermillion MS,Ursin RL,Attreed SE,Klein SL
11-5931-82 was used in Flow cytometry/Cell sorting to suggest that exogenous E3 confers protection during IAV infection through immunomodulatory mechanisms and that E3 may have broad therapeutic potential in the context of both infectious and noninfectious inflammatory diseases.
Sat Sep 01 00:00:00 EDT 2018
Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.
Nature medicine
Giles DA,Moreno-Fernandez ME,Stankiewicz TE,Graspeuntner S,Cappelletti M,Wu D,Mukherjee R,Chan CC,Lawson MJ,Klarquist J,Sünderhauf A,Softic S,Kahn CR,Stemmer K,Iwakura Y,Aronow BJ,Karns R,Steinbrecher KA,Karp CL,Sheridan R,Shanmukhappa SK,Reynaud D,Haslam DB,Sina C,Rupp J,Hogan SP,Divanovic S
11-5931 was used in Flow cytometry/Cell sorting to show thermoneutral housing provides a sex-independent model of exacerbated NAFLD in mice and represents a novel approach for interrogation of the cellular and molecular mechanisms underlying disease pathogenesis.
Sat Jul 01 00:00:00 EDT 2017
Staphylococcal serine protease-like proteins are pacemakers of allergic airway reactions to Staphylococcus aureus.
The Journal of allergy and clinical immunology
Stentzel S,Teufelberger A,Nordengrün M,Kolata J,Schmidt F,van Crombruggen K,Michalik S,Kumpfmüller J,Tischer S,Schweder T,Hecker M,Engelmann S,Völker U,Krysko O,Bachert C,Bröker BM
11593182 was used in flow cytometry to discuss Staphylococcus aureus-derived allergens
Wed Feb 01 00:00:00 EST 2017
GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia.
Developmental cell
Hewitt KJ,Katsumura KR,Matson DR,Devadas P,Tanimura N,Hebert AS,Coon JJ,Kim JS,Dewey CN,Keles S,Hao S,Paulson RF,Bresnick EH
11-5931 was used in Flow cytometry/Cell sorting to propose that Samd14-Enh and an ensemble of anemia-responsive enhancers are essential for erythrocyte regeneration in stress erythropoiesis.
Mon Aug 07 00:00:00 EDT 2017
Pathogen response-like recruitment and activation of neutrophils by sterile immunogenic dying cells drives neutrophil-mediated residual cell killing.
Cell death and differentiation
Garg AD,Vandenberk L,Fang S,Fasche T,Van Eygen S,Maes J,Van Woensel M,Koks C,Vanthillo N,Graf N,de Witte P,Van Gool S,Salven P,Agostinis P
11-5931 was used in Flow cytometry/Cell sorting to determine the role of sterile dying cells in the stimulation of innate immunity.
Mon May 01 00:00:00 EDT 2017
Bacillus anthracis lethal toxin negatively modulates ILC3 function through perturbation of IL-23-mediated MAPK signaling.
PLoS pathogens
Seshadri S,Allan DSJ,Carlyle JR,Zenewicz LA
11-5931 was used in Flow cytometry/Cell sorting to study the effects of MAPK signalling pathways in group 3 innate immune lymphocytes using Bacillus anthracis.
Sun Oct 01 00:00:00 EDT 2017
Aging-related Atg5 defect impairs neutrophil extracellular traps formation.
Immunology
Xu F,Zhang C,Zou Z,Fan EKY,Chen L,Li Y,Billiar TR,Wilson MA,Shi X,Fan J
11-5931 was used in Flow cytometry/Cell sorting to suggest an important role of Atg5 and autophagy in maintaining the function of neutrophil extracellular trap formation.
Tue Aug 01 00:00:00 EDT 2017
Human umbilical cord blood-borne fibroblasts contain marrow niche precursors that form a bone/marrow organoid in vivo.
Development (Cambridge, England)
Pievani A,Sacchetti B,Corsi A,Rambaldi B,Donsante S,Scagliotti V,Vergani P,Remoli C,Biondi A,Robey PG,Riminucci M,Serafini M
11-5931 was used in Flow cytometry/Cell sorting to show that human umbilical cord blood-borne fibroblasts are able to recapitulate the conditions by which the bone marrow microenvironment is formed and establish complete hematopoietic stem cell niches.
Wed Mar 15 00:00:00 EDT 2017
Cardiac inflammation in genetic dilated cardiomyopathy caused by MYBPC3 mutation.
Journal of molecular and cellular cardiology
Lynch TL,Ismahil MA,Jegga AG,Zilliox MJ,Troidl C,Prabhu SD,Sadayappan S
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
Cardiac inflammation in genetic dilated cardiomyopathy caused by MYBPC3 mutation.
Journal of molecular and cellular cardiology
Lynch TL,Ismahil MA,Jegga AG,Zilliox MJ,Troidl C,Prabhu SD,Sadayappan S
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
Autophagy in Dendritic Cells and B Cells Is Critical for the Inflammatory State of TLR7-Mediated Autoimmunity.
Journal of immunology (Baltimore, Md. : 1950)
Weindel CG,Richey LJ,Mehta AJ,Shah M,Huber BT
11-5931 was used in Flow cytometry/Cell sorting to identify that autophagy in B cells and dendritic cells are key to TLR7-mediated autoimmune disorders.
Wed Feb 01 00:00:00 EST 2017
Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-κB signaling and NLRP3 activation.
International journal of molecular medicine
Zhang B,Wang B,Cao S,Wang Y,Wu D
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.
RNA biology
Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Thu May 04 00:00:00 EDT 2017
Coinjection of IL2 DNA enhances E7-specific antitumor immunity elicited by intravaginal therapeutic HPV DNA vaccination with electroporation.
Gene therapy
Sun Y,Peng S,Yang A,Farmer E,Wu TC,Hung CF
11-5931 was used in Flow cytometry/Cell sorting to assess the therapeutic efficacy of intravaginal immunisation with human papillomavirus pcDNA3-CRT/E7 followed by electroporation.
Sat Jul 01 00:00:00 EDT 2017
MDSCs are involved in the protumorigenic potentials of GM-CSF in colitis-associated cancer.
International journal of immunopathology and pharmacology
Ma N,Liu Q,Hou L,Wang Y,Liu Z
Thu Jun 01 00:00:00 EDT 2017
MiR-125a Is a critical modulator for neutrophil development.
PLoS genetics
Qin Y,Wu L,Ouyang Y,Zhou P,Zhou H,Wang Y,Ma J,Zhang J,Chen Y,Qian J,Tang Y,Shen N
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells.
Oncotarget
Guo XL,Chu L,Ke F,Mu LL,Li Z,Cai JJ,Li HF,Hong DL
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Tue Dec 12 00:00:00 EST 2017
BOT-4-one attenuates NLRP3 inflammasome activation: NLRP3 alkylation leading to the regulation of its ATPase activity and ubiquitination.
Scientific reports
Shim DW,Shin WY,Yu SH,Kim BH,Ye SK,Koppula S,Won HS,Kang TB,Lee KH
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Wed Nov 08 00:00:00 EST 2017
Characterisation of innate lymphoid cell populations at different sites in mice with defective T cell immunity.
Wellcome open research
Dutton EE,Camelo A,Sleeman M,Herbst R,Carlesso G,Belz GT,Withers DR
11-5931-82 was used in Flow Cytometry to compare the innate lymphoid cell populations at different sites in mice with defective T cell immunity.
Sat Jan 09 00:00:00 EST 2021
Gastric TFF1 Expression from Acute to Chronic Helicobacter Infection.
Frontiers in cellular and infection microbiology
Esposito R,Morello S,Vllahu M,Eletto D,Porta A,Tosco A
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunohistochemistry
Mon Jul 09 00:00:00 EDT 2018
Tumor-Derived Exosomes Induce the Formation of Neutrophil Extracellular Traps: Implications For The Establishment of Cancer-Associated Thrombosis.
Scientific reports
Leal AC,Mizurini DM,Gomes T,Rochael NC,Saraiva EM,Dias MS,Werneck CC,Sielski MS,Vicente CP,Monteiro RQ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunohistochemistry
Tue Jul 25 00:00:00 EDT 2017
E3 ligase FBXW7 is critical for RIG-I stabilization during antiviral responses.
Nature communications
Song Y,Lai L,Chong Z,He J,Zhang Y,Xue Y,Xie Y,Chen S,Dong P,Chen L,Chen Z,Dai F,Wan X,Xiao P,Cao X,Liu Y,Wang Q
11-5931 was used in Flow cytometry/Cell sorting to identify FBXW7 as an important interacting partner for RIG-I.
Mon Mar 13 00:00:00 EDT 2017
Small molecule p300/catenin antagonist enhances hematopoietic recovery after radiation.
PloS one
Zhao Y,Wu K,Nguyen C,Smbatyan G,Melendez E,Higuchi Y,Chen Y,Kahn M
11-5931 was used in Flow cytometry/Cell sorting to report that the small molecule YH250 stimulates hematopoiesis in lethally or sublethally irradiated mice.
Tue Sep 26 00:00:00 EDT 2017
Azacytidine prevents experimental xenogeneic graft-versus-host disease without abrogating graft-versus-leukemia effects.
Oncoimmunology
Ehx G,Fransolet G,de Leval L,D'Hondt S,Lucas S,Hannon M,Delens L,Dubois S,Drion P,Beguin Y,Humblet-Baron S,Baron F
11-5931 was used in Flow cytometry/Cell sorting to investigate the impact of 5-azacytidine on xenogeneic graft-vs.-host disease and graft-vs.-leukaemia effects in a humanised murine model of transplantation.
Tue Jan 12 00:00:00 EST 2021
Loss of MAPK-activated protein kinase 2 enables potent dendritic cell-driven anti-tumour T cell response.
Scientific reports
Soukup K,Halfmann A,Dillinger B,Poyer F,Martin K,Blauensteiner B,Kauer M,Kuttke M,Schabbauer G,Dohnal AM
11-5931 was used in Flow cytometry/Cell sorting to suggest that MAPK-activated protein kinase 2 deletion leads to an expansion of stimulatory CD103+ dendritic cells, mounting a potent CD8+ T cell anti-tumour response in mice.
Mon Sep 18 00:00:00 EDT 2017
One Year Follow-Up Risk Assessment in SKH-1 Mice and Wounds Treated with an Argon Plasma Jet.
International journal of molecular sciences
Schmidt A,Woedtke TV,Stenzel J,Lindner T,Polei S,Vollmar B,Bekeschus S
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunofluorescence
Wed Apr 19 00:00:00 EDT 2017
Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes.
Proceedings of the National Academy of Sciences of the United States of America
Hara T,Nakaoka HJ,Hayashi T,Mimura K,Hoshino D,Inoue M,Nagamura F,Murakami Y,Seiki M,Sakamoto T
11-5931-82 was used in Flow cytometry/Cell sorting to report that APBA3-deficient mice show reduced metastasis, with no apparent effect on primary tumor growth.
Tue May 30 00:00:00 EDT 2017
Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates.
Nature biotechnology
Vegas AJ,Veiseh O,Doloff JC,Ma M,Tam HH,Bratlie K,Li J,Bader AR,Langan E,Olejnik K,Fenton P,Kang JW,Hollister-Locke J,Bochenek MA,Chiu A,Siebert S,Tang K,Jhunjhunwala S,Aresta-Dasilva S,Dholakia N,Thakrar R,Vietti T,Chen M,Cohen J,Siniakowicz K,Qi M,McGarrigle J,Graham AC,Lyle S,Harlan DM,Greiner DL,Oberholzer J,Weir GC,Langer R,Anderson DG
Tue Mar 01 00:00:00 EST 2016
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Thu Aug 25 00:00:00 EDT 2016
NLRP2 controls age-associated maternal fertility.
The Journal of experimental medicine
Kuchmiy AA,D'Hont J,Hochepied T,Lamkanfi M
11-5931 was used in Flow cytometry/Cell sorting to identify Nlrp2 as a critical regulator of oocyte quality.
Mon Dec 12 00:00:00 EST 2016
G-CSF is a key modulator of MDSC and could be a potential therapeutic target in colitis-associated colorectal cancers.
Protein & cell
Li W,Zhang X,Chen Y,Xie Y,Liu J,Feng Q,Wang Y,Yuan W,Ma J
11-5931 was used in Flow cytometry/Cell sorting to indicate that G-CSF is a critical regulating molecule in the migration, proliferation and functional maintenance of myeloid derived suppressor cells.
Mon Feb 01 00:00:00 EST 2016
Innate lymphoid cells contribute to allergic airway disease exacerbation by obesity.
The Journal of allergy and clinical immunology
Everaere L,Ait-Yahia S,Molendi-Coste O,Vorng H,Quemener S,LeVu P,Fleury S,Bouchaert E,Fan Y,Duez C,de Nadai P,Staels B,Dombrowicz D,Tsicopoulos A
11-5931 was used in Flow cytometry/Cell sorting to indicate that high-fat diet-induced obesity might exacerbate allergic airway inflammation through mechanisms involving ILC2s and ILC3s.
Tue Nov 01 00:00:00 EDT 2016
Multiple myeloma exosomes establish a favourable bone marrow microenvironment with enhanced angiogenesis and immunosuppression.
The Journal of pathology
Wang J,De Veirman K,Faict S,Frassanito MA,Ribatti D,Vacca A,Menu E
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
β7-Integrin exacerbates experimental DSS-induced colitis in mice by directing inflammatory monocytes into the colon.
Mucosal immunology
Schippers A,Muschaweck M,Clahsen T,Tautorat S,Grieb L,Tenbrock K,Gaßler N,Wagner N
11-5931 was used in Flow cytometry/Cell sorting to elucidate the significance of β7-integrin expression on innate immune cells for the pathogenesis of inflammatory bowel disease.
Tue Mar 01 00:00:00 EST 2016
Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth.
Stem cells translational medicine
Zheng H,Zou W,Shen J,Xu L,Wang S,Fu YX,Fan W
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.
Immunology
Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Sat Oct 01 00:00:00 EDT 2016
In vivo induction of neutrophil chemotaxis by secretory aspartyl proteinases of Candida albicans.
Virulence
Gabrielli E,Sabbatini S,Roselletti E,Kasper L,Perito S,Hube B,Cassone A,Vecchiarelli A,Pericolini E
11-5931 was used in Flow cytometry/Cell sorting to provide additional information on the capacity of C. albicans Saps to cause aseptic vaginal inflammation.
Sun Oct 02 00:00:00 EDT 2016
G-CSF-Induced Suppressor IL-10+ Neutrophils Promote Regulatory T Cells That Inhibit Graft-Versus-Host Disease in a Long-Lasting and Specific Way.
Journal of immunology (Baltimore, Md. : 1950)
Perobelli SM,Mercadante AC,Galvani RG,Gonçalves-Silva T,Alves AP,Pereira-Neves A,Benchimol M,Nóbrega A,Bonomo A
11-5931 was used in Flow cytometry/Cell sorting to study the role of incoming IL-10+ neutrophils from G-CSF-treated donor spleen in inhibiting acute graft-versus-host disease.
Tue Nov 01 00:00:00 EDT 2016
The miR-17∼92 cluster contributes to MLL leukemia through the repression of MEIS1 competitor PKNOX1.
Leukemia research
Mian YA,Zeleznik-Le NJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Fri Jul 01 00:00:00 EDT 2016
Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.
Stem cell reports
Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Tue Aug 09 00:00:00 EDT 2016
Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury.
Cell death & disease
Di Siena S,Gimmelli R,Nori SL,Barbagallo F,Campolo F,Dolci S,Rossi P,Venneri MA,Giannetta E,Gianfrilli D,Feigenbaum L,Lenzi A,Naro F,Cianflone E,Mancuso T,Torella D,Isidori AM,Pellegrini M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunofluorescence
Thu Jul 28 00:00:00 EDT 2016
Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury.
Cell death & disease
Di Siena S,Gimmelli R,Nori SL,Barbagallo F,Campolo F,Dolci S,Rossi P,Venneri MA,Giannetta E,Gianfrilli D,Feigenbaum L,Lenzi A,Naro F,Cianflone E,Mancuso T,Torella D,Isidori AM,Pellegrini M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunofluorescence
Thu Jul 28 00:00:00 EDT 2016
Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice.
BMC genomics
Leist SR,Pilzner C,van den Brand JM,Dengler L,Geffers R,Kuiken T,Balling R,Kollmus H,Schughart K
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Sat Feb 27 00:00:00 EST 2016
Expression of the inhibitory Ly49E receptor is not critically involved in the immune response against cutaneous, pulmonary or liver tumours.
Scientific reports
Filtjens J,Keirsse J,Van Ammel E,Taveirne S,Van Acker A,Kerre T,Taghon T,Vandekerckhove B,Plum J,Van Ginderachter JA,Leclercq G
11-5931 was used in Flow cytometry/Cell sorting to study the involvement of the inhibitory Ly49E NK cell receptor and its activating molecule uPA in skin, lung, and liver tumorigenesis.
Fri Jul 29 00:00:00 EDT 2016
Regulation of Inflammation by IL-17A and IL-17F Modulates Non-Alcoholic Fatty Liver Disease Pathogenesis.
PloS one
Giles DA,Moreno-Fernandez ME,Stankiewicz TE,Cappelletti M,Huppert SS,Iwakura Y,Dong C,Shanmukhappa SK,Divanovic S
11-5931 was used in Flow cytometry/Cell sorting to indicate that the IL-17 axis also plays a role in a MCDD-induced model of NAFLD pathogenesis.
Tue Jul 19 00:00:00 EDT 2016
SCIB1, a huIgG1 antibody DNA vaccination, combined with PD-1 blockade induced efficient therapy of poorly immunogenic tumors.
Oncotarget
Xue W,Brentville VA,Symonds P,Cook KW,Yagita H,Metheringham RL,Durrant LG
11-5931 was used in Flow cytometry/Cell sorting to investigate the anti-tumour effect of a huIgG1 antibody DNA vaccine and PD-1 blockade.
Tue Dec 13 00:00:00 EST 2016
miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia.
Nature communications
Jiang X,Hu C,Arnovitz S,Bugno J,Yu M,Zuo Z,Chen P,Huang H,Ulrich B,Gurbuxani S,Weng H,Strong J,Wang Y,Li Y,Salat J,Li S,Elkahloun AG,Yang Y,Neilly MB,Larson RA,Le Beau MM,Herold T,Bohlander SK,Liu PP,Zhang J,Li Z,He C,Jin J,Hong S,Chen J
11-5931 was used in Flow cytometry/Cell sorting to investigate the anti-tumourigenic role of miR-22, showing that it has an anti-tumour role in acute myeloid leukaemia.
Tue Apr 26 00:00:00 EDT 2016
Stroke Damage Is Exacerbated by Nano-Size Particulate Matter in a Mouse Model.
PloS one
Liu Q,Babadjouni R,Radwanski R,Cheng H,Patel A,Hodis DM,He S,Baumbacher P,Russin JJ,Morgan TE,Sioutas C,Finch CE,Mack WJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunofluorescence
Tue Aug 23 00:00:00 EDT 2016
Neutropenic Mice Provide Insight into the Role of Skin-Infiltrating Neutrophils in the Host Protective Immunity against Filarial Infective Larvae.
PLoS neglected tropical diseases
Pionnier N,Brotin E,Karadjian G,Hemon P,Gaudin-Nomé F,Vallarino-Lhermitte N,Nieguitsila A,Fercoq F,Aknin ML,Marin-Esteban V,Chollet-Martin S,Schlecht-Louf G,Bachelerie F,Martin C
11-5931 was used in Flow cytometry/Cell sorting to demonstrate that neutrophils contribute to early anti-filarial host responses via oxidative burst, degranulation and NETosis.
Fri Apr 01 00:00:00 EDT 2016
Kruppel-like Factor 6 Promotes Macrophage-mediated Inflammation by Suppressing B Cell Leukemia/Lymphoma 6 Expression.
The Journal of biological chemistry
Kim GD,Das R,Goduni L,McClellan S,Hazlett LD,Mahabeleshwar GH
11-5931 was used in Flow cytometry/Cell sorting to identify KLF6/BCL6 signaling axis as a novel regulator of macrophage inflammatory gene expression and function.
Fri Sep 30 00:00:00 EDT 2016
C/EBP homologous protein (CHOP) deficiency ameliorates renal fibrosis in unilateral ureteral obstructive kidney disease.
Oncotarget
Liu SH,Wu CT,Huang KH,Wang CC,Guan SS,Chen LP,Chiang CK
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunohistochemistry
Tue Apr 19 00:00:00 EDT 2016
Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors.
Nature communications
Cheng H,Ang HY,A El Farran C,Li P,Fang HT,Liu TM,Kong SL,Chin ML,Ling WY,Lim EK,Li H,Huber T,Loh KM,Loh YH,Lim B
11-5931 was used in Flow cytometry/Cell sorting to demonstrate how it is possible to reprogram mouse embryonic fibroblasts into engraftable blood progenitors.
Mon Nov 21 00:00:00 EST 2016
Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma.
Oncoimmunology
Vandenberk L,Garg AD,Verschuere T,Koks C,Belmans J,Beullens M,Agostinis P,De Vleeschouwer S,Van Gool SW
11-5931 was used in Flow cytometry/Cell sorting to advocate the use of protein oxidation-inducing modalities like irradiation for increasing the immunogenicity of tumour lysate/cells used for pulsing DC vaccines.
Mon Feb 01 00:00:00 EST 2016
Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.
Blood
Matthews GM,Mehdipour P,Cluse LA,Falkenberg KJ,Wang E,Roth M,Santoro F,Vidacs E,Stanley K,House CM,Rusche JR,Vakoc CR,Zuber J,Minucci S,Johnstone RW
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Thu Nov 19 00:00:00 EST 2015
Inflammation rapidly reorganizes mouse bone marrow B cells and their environment in conjunction with early IgM responses.
Blood
Moreau JM,Berger A,Nelles ME,Mielnik M,Furlonger C,Cen SY,Besla R,Robbins CS,Paige CJ
11-5931 was used in Flow cytometry/Cell sorting to study the rapidity with which peripheral inflammation modifies the bone marrow compartment, and demonstrate that such modifications regulate acute IgM production within this organ.
Thu Sep 03 00:00:00 EDT 2015
Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling.
The Journal of clinical investigation
Quinn KM,Zak DE,Costa A,Yamamoto A,Kastenmuller K,Hill BJ,Lynn GM,Darrah PA,Lindsay RW,Wang L,Cheng C,Nicosia A,Folgori A,Colloca S,Cortese R,Gostick E,Price DA,Gall JG,Roederer M,Aderem A,Seder RA
11-5931 was used in Flow cytometry/Cell sorting to investigate the mechanisms that control the potency of CD8 T cell responses in murine models following vaccination with recombinant adenoviral vectors encoding SIV-Gag antigen.
Mon Mar 02 00:00:00 EST 2015
Imaging the dynamic platelet-neutrophil response in sterile liver injury and repair in mice.
Hepatology (Baltimore, Md.)
Slaba I,Wang J,Kolaczkowska E,McDonald B,Lee WY,Kubes P
11-5931 was used to study the role of platelets in sterile liver injury and repair.
Sun Nov 01 00:00:00 EDT 2015
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
11-5931 was used in Flow cytometry/Cell sorting to illustrate a paradigm in which cis-elements in a locus differentially control stem and progenitor cell transitions.
Tue Sep 01 00:00:00 EDT 2015
B cell autophagy mediates TLR7-dependent autoimmunity and inflammation.
Autophagy
Weindel CG,Richey LJ,Bolland S,Mehta AJ,Kearney JF,Huber BT
11-5931 was used in Flow cytometry/Cell sorting to demonstrate that autophagy plays an essential role in TLR7 activation of B cells for the induction of systemic lupus erythematosus.
Mon Apr 18 00:00:00 EDT 2016
Premature thymic involution is independent of structural plasticity of the thymic stroma.
European journal of immunology
Franckaert D,Schlenner SM,Heirman N,Gill J,Skogberg G,Ekwall O,Put K,Linterman MA,Dooley J,Liston A
11-5931 was used in Flow cytometry/Cell sorting to investigate thymic involution in FVB/N mice, showing that disruption of the epithelial-endothelial relationship and a progressive loss of pro-T cells precedes involution, and loss of pro-T cells is sufficient to drive premature involution, suggesting that pro-T cells are the main driver of involution.
Fri May 01 00:00:00 EDT 2015
Intratumoral INF-γ triggers an antiviral state in GL261 tumor cells: a major hurdle to overcome for oncolytic vaccinia virus therapy of cancer.
Molecular therapy oncolytics
Kober C,Weibel S,Rohn S,Kirscher L,Szalay AA
11-5931 was used in Flow cytometry/Cell sorting to identify microenvironmental factors, which may be decisive for failure or success of oncolytic VACV therapy.
Wed Apr 27 00:00:00 EDT 2016
The receptor for advanced glycation end products (RAGE) enhances autophagy and neutrophil extracellular traps in pancreatic cancer.
Cancer gene therapy
Boone BA,Orlichenko L,Schapiro NE,Loughran P,Gianfrate GC,Ellis JT,Singhi AD,Kang R,Tang D,Lotze MT,Zeh HJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunofluorescence
Mon Jun 01 00:00:00 EDT 2015
The receptor for advanced glycation end products (RAGE) enhances autophagy and neutrophil extracellular traps in pancreatic cancer.
Cancer gene therapy
Boone BA,Orlichenko L,Schapiro NE,Loughran P,Gianfrate GC,Ellis JT,Singhi AD,Kang R,Tang D,Lotze MT,Zeh HJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunofluorescence
Mon Jun 01 00:00:00 EDT 2015
Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis.
Journal of molecular medicine (Berlin, Germany)
Peng H,Li C,Kadow S,Henry BD,Steinmann J,Becker KA,Riehle A,Beckmann N,Wilker B,Li PL,Pritts T,Edwards MJ,Zhang Y,Gulbins E,Grassmé H
11-5931 was used in Flow cytometry/Cell sorting to investigate the role of the mammalian acid sphingomyelinase (Asm)/ceramide system in the development of lung edema caused by S. aureus.
Mon Jun 01 00:00:00 EDT 2015
Spred1, a Suppressor of the Ras-ERK Pathway, Negatively Regulates Expansion and Function of Group 2 Innate Lymphoid Cells.
Journal of immunology (Baltimore, Md. : 1950)
Suzuki M,Morita R,Hirata Y,Shichita T,Yoshimura A
11-5931 was used in Flow cytometry/Cell sorting to demonstrate that Spred1, a negative regulator of the Ras-ERK pathway, plays an important role in the proliferation and apoptosis of ILC2s and in cytokine secretion from ILC2s.
Sat Aug 01 00:00:00 EDT 2015
Immunosuppression-Independent Role of Regulatory T Cells against Hypertension-Driven Renal Dysfunctions.
Molecular and cellular biology
Fabbiano S,Menacho-Márquez M,Robles-Valero J,Pericacho M,Matesanz-Marín A,García-Macías C,Sevilla MA,Montero MJ,Alarcón B,López-Novoa JM,Martín P,Bustelo XR
11-5931 was used in Flow cytometry/Cell sorting to determine that TREG cells constitute a first protective barrier against hypertension-driven tissue fibrosis.
Thu Oct 01 00:00:00 EDT 2015
A far-red fluorescent probe for flow cytometry and image-based functional studies of xenobiotic sequestering macrophages.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Keswani RK,Yoon GS,Sud S,Stringer KA,Rosania GR
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Local delivery of VEGF and SDF enhances endothelial progenitor cell recruitment and resultant recovery from ischemia.
Tissue engineering. Part A
Anderson EM,Kwee BJ,Lewin SA,Raimondo T,Mehta M,Mooney DJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway.
Molecular medicine reports
Huang L,Kong Y,Wang J,Sun J,Shi Q,Qiu YH
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
The bone marrow microenvironment enhances multiple myeloma progression by exosome-mediated activation of myeloid-derived suppressor cells.
Oncotarget
Wang J,De Veirman K,De Beule N,Maes K,De Bruyne E,Van Valckenborgh E,Vanderkerken K,Menu E
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Tue Dec 22 00:00:00 EST 2015
Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.
PloS one
Szulzewsky F,Pelz A,Feng X,Synowitz M,Markovic D,Langmann T,Holtman IR,Wang X,Eggen BJ,Boddeke HW,Hambardzumyan D,Wolf SA,Kettenmann H
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2016
Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts.
Stem cell reports
Neri T,Muggeo S,Paulis M,Caldana ME,Crisafulli L,Strina D,Focarelli ML,Faggioli F,Recordati C,Scaramuzza S,Scanziani E,Mantero S,Buracchi C,Sobacchi C,Lombardo A,Naldini L,Vezzoni P,Villa A,Ficara F
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Tue Oct 13 00:00:00 EDT 2015
Sunitinib depletes myeloid-derived suppressor cells and synergizes with a cancer vaccine to enhance antigen-specific immune responses and tumor eradication.
Oncoimmunology
Draghiciu O,Nijman HW,Hoogeboom BN,Meijerhof T,Daemen T
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2015
The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity.
Nature communications
Sag D,Cekic C,Wu R,Linden J,Hedrick CC
11-5931 was used in Flow cytometry/Cell sorting to demonstrate that the absence of ABCG1 inhibits tumour growth through modulation of macrophage function within the tumour.
Fri Feb 27 00:00:00 EST 2015
The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia.
Nature communications
Koh HS,Chang CY,Jeon SB,Yoon HJ,Ahn YH,Kim HS,Kim IH,Jeon SH,Johnson RS,Park EJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunofluorescence
Fri Mar 20 00:00:00 EDT 2015
Myeloid cell-derived inducible nitric oxide synthase suppresses M1 macrophage polarization.
Nature communications
Lu G,Zhang R,Geng S,Peng L,Jayaraman P,Chen C,Xu F,Yang J,Li Q,Zheng H,Shen K,Wang J,Liu X,Wang W,Zheng Z,Qi CF,Si C,He JC,Liu K,Lira SA,Sikora AG,Li L,Xiong H
11-5931 was used in Flow cytometry/Cell sorting to show that iNOS-deficient mice display enhanced classically activated M1 macrophage polarization without major effects on alternatively activated M2 macrophages.
Fri Mar 27 00:00:00 EDT 2015
Severity of DSS-induced colitis is reduced in Ido1-deficient mice with down-regulation of TLR-MyD88-NF-kB transcriptional networks.
Scientific reports
Shon WJ,Lee YK,Shin JH,Choi EY,Shin DM
11-5931 was used in Flow cytometry/Cell sorting to explore the role of IDO1 in producing inflammatory responses and modulating transcriptional networks during the development of colitis.
Fri Nov 27 00:00:00 EST 2015
Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature.
Nature communications
Kolaczkowska E,Jenne CN,Surewaard BG,Thanabalasuriar A,Lee WY,Sanz MJ,Mowen K,Opdenakker G,Kubes P
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunofluorescence
Thu Mar 26 00:00:00 EDT 2015
Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion.
Nature medicine
Bruns I,Lucas D,Pinho S,Ahmed J,Lambert MP,Kunisaki Y,Scheiermann C,Schiff L,Poncz M,Bergman A,Frenette PS
11-5931 was used in Flow cytometry/Cell sorting to indicate that a terminally differentiated cell type derived from HSCs contributes to the HSC niche, directly regulating HSC behavior.
Sat Nov 01 00:00:00 EDT 2014
An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action.
Nature medicine
Gibbs J,Ince L,Matthews L,Mei J,Bell T,Yang N,Saer B,Begley N,Poolman T,Pariollaud M,Farrow S,DeMayo F,Hussell T,Worthen GS,Ray D,Loudon A
11-5931 was used in Flow cytometry/Cell sorting to study the regulatory mechanism linking the circadian clock and glucocorticoid hormones, to control time-of-day variation and the magnitude of pulmonary inflammation.
Fri Aug 01 00:00:00 EDT 2014
Host adaptation of a bacterial toxin from the human pathogen Salmonella Typhi.
Cell
Deng L,Song J,Gao X,Wang J,Yu H,Chen X,Varki N,Naito-Matsui Y,Galán JE,Varki A
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Thu Dec 04 00:00:00 EST 2014
Host adaptation of a bacterial toxin from the human pathogen Salmonella Typhi.
Cell
Deng L,Song J,Gao X,Wang J,Yu H,Chen X,Varki N,Naito-Matsui Y,Galán JE,Varki A
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Thu Dec 04 00:00:00 EST 2014
Endothelial C-type natriuretic peptide maintains vascular homeostasis.
The Journal of clinical investigation
Moyes AJ,Khambata RS,Villar I,Bubb KJ,Baliga RS,Lumsden NG,Xiao F,Gane PJ,Rebstock AS,Worthington RJ,Simone MI,Mota F,Rivilla F,Vallejo S,Peiró C,Sánchez Ferrer CF,Djordjevic S,Caulfield MJ,MacAllister RJ,Selwood DL,Ahluwalia A,Hobbs AJ
11-5931 was used in Flow cytometry/Cell sorting to evaluate mice with endothelial-specific deletion of C-type natriuretic peptide (CNP), showing that it is essential for multiple aspects of vascular regulation.
Mon Sep 01 00:00:00 EDT 2014
Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain.
The Journal of clinical investigation
Old EA,Nadkarni S,Grist J,Gentry C,Bevan S,Kim KW,Mogg AJ,Perretti M,Malcangio M
11-5931 was used in Flow cytometry/Cell sorting to delineate a pathway for pain that is induced by the chemotherapeutic drug vincristine sulphate.
Thu May 01 00:00:00 EDT 2014
12-Hydroxyheptadecatrienoic acid promotes epidermal wound healing by accelerating keratinocyte migration via the BLT2 receptor.
The Journal of experimental medicine
Liu M,Saeki K,Matsunobu T,Okuno T,Koga T,Sugimoto Y,Yokoyama C,Nakamizo S,Kabashima K,Narumiya S,Shimizu T,Yokomizo T
11-5931 was used in Flow cytometry/Cell sorting to demonstrate the potential use of BLT2 agonists as therapeutic agents to accelerate wound healing.
Mon Jun 02 00:00:00 EDT 2014
Contribution of mast cell-derived interleukin-1β to uric acid crystal-induced acute arthritis in mice.
Arthritis & rheumatology (Hoboken, N.J.)
Reber LL,Marichal T,Sokolove J,Starkl P,Gaudenzio N,Iwakura Y,Karasuyama H,Schwartz LB,Robinson WH,Tsai M,Galli SJ
11-5931 was used in Flow cytometry/Cell sorting to assess the role of mast cells in a mouse model of monosodium urate monohydrate crystal-induced acute arthritis.
Wed Oct 01 00:00:00 EDT 2014
Fas (CD95) expression in myeloid cells promotes obesity-induced muscle insulin resistance.
EMBO molecular medicine
Wueest S,Mueller R,Blüher M,Item F,Chin AS,Wiedemann MS,Takizawa H,Kovtonyuk L,Chervonsky AV,Schoenle EJ,Manz MG,Konrad D
11-5931 was used in Flow cytometry/Cell sorting to demonstrate an unanticipated crosstalk between myeloid cells and skeletal muscle in the development of obesity-associated insulin resistance.
Wed Jan 01 00:00:00 EST 2014
Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis.
Autophagy
Dang S,Xu H,Xu C,Cai W,Li Q,Cheng Y,Jin M,Wang RX,Peng Y,Zhang Y,Wu C,He X,Wan B,Zhang Y
11-5931 was used in Flow cytometry/Cell sorting to study how inflammatory microenvironment-induced autophagy can downregulate the immunosuppressive function of mesenchymal stem cells.
Tue Jul 01 00:00:00 EDT 2014
Macrophages contribute to the cyclic activation of adult hair follicle stem cells.
PLoS biology
Castellana D,Paus R,Perez-Moreno M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Mon Dec 01 00:00:00 EST 2014
Secretion of IL-16 through TNFR1 and calpain-caspase signaling contributes to MRSA pneumonia.
Mucosal immunology
Ahn DS,Parker D,Planet PJ,Nieto PA,Bueno SM,Prince A
11-5931 was used in Flow cytometry/Cell sorting to study the role of IL-16 in disease progression of S. aureus pneumonia.
Sat Nov 01 00:00:00 EDT 2014
Intranasal vaccination promotes detrimental Th17-mediated immunity against influenza infection.
PLoS pathogens
Maroof A,Yorgensen YM,Li Y,Evans JT
11-5931 was used in Flow cytometry/Cell sorting to highlight the importance of both route of vaccination and adjuvant selection in vaccine development.
Wed Jan 01 00:00:00 EST 2014
Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization.
Development (Cambridge, England)
Plosa EJ,Young LR,Gulleman PM,Polosukhin VV,Zaynagetdinov R,Benjamin JT,Im AM,van der Meer R,Gleaves LA,Bulus N,Han W,Prince LS,Blackwell TS,Zent R
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunofluorescence
Mon Dec 01 00:00:00 EST 2014
Bleomycin delivery by osmotic minipump: similarity to human scleroderma interstitial lung disease.
American journal of physiology. Lung cellular and molecular physiology
Lee R,Reese C,Bonner M,Tourkina E,Hajdu Z,Riemer EC,Silver RM,Visconti RP,Hoffman S
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunofluorescence
Tue Apr 15 00:00:00 EDT 2014
Kinetics of IFN-γ and IL-17 Production by CD4 and CD8 T Cells during Acute Graft-versus-Host Disease.
Immune network
Ju JM,Lee H,Oh K,Lee DS,Choi EY
11-5931 was used in Flow cytometry/Cell sorting to study production of IFN-γ and IL-17 by CD4 and CD8 T cells during graft-versus-host disease progression.
Tue Apr 01 00:00:00 EDT 2014
Wnt5a regulates hematopoietic stem cell proliferation and repopulation through the Ryk receptor.
Stem cells (Dayton, Ohio)
Povinelli BJ,Nemeth MJ
11-5931 was used in Flow cytometry/Cell sorting to study whether Ryk protein regulates the response of haematopoietic stem cells to Wnt5a.
Wed Jan 01 00:00:00 EST 2014
Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in viral infection.
Journal of immunology (Baltimore, Md. : 1950)
Jie Z,Liang Y,Hou L,Dong C,Iwakura Y,Soong L,Cong Y,Sun J
11-5931 was used in Flow cytometry/Cell sorting to investigate the source and regulation of the IL-17 surge in the liver microenvironment that occurs early in the response to viral infection.
Tue Apr 01 00:00:00 EDT 2014
Human hematopoietic reconstitution and HLA-restricted responses in nonpermissive alymphoid mice.
Journal of immunology (Baltimore, Md. : 1950)
Serra-Hassoun M,Bourgine M,Boniotto M,Berges J,Langa F,Michel ML,Freitas AA,Garcia S
11-5931 was used in Flow cytometry/Cell sorting to generate a new humanised mouse model to study HLA-restricted immune responses.
Fri Aug 01 00:00:00 EDT 2014
GM-CSF but not IL-17 is critical for the development of severe interstitial lung disease in SKG mice.
Journal of immunology (Baltimore, Md. : 1950)
Shiomi A,Usui T,Ishikawa Y,Shimizu M,Murakami K,Mimori T
11-5931 was used in Flow cytometry/Cell sorting to investigate the importance of GM-CSF in the development of severe interstitial lung disease.
Tue Jul 15 00:00:00 EDT 2014
Yersinia pseudotuberculosis efficiently escapes polymorphonuclear neutrophils during early infection.
Infection and immunity
Westermark L,Fahlgren A,Fällman M
11-5931 was used in Flow cytometry/Cell sorting to analyse bacterium-immune cell interactions in the intestinal lymphoid tissues of mice during early Yersinia pseudotuberculosis infection.
Sat Mar 01 00:00:00 EST 2014
Superantigens subvert the neutrophil response to promote abscess formation and enhance Staphylococcus aureus survival in vivo.
Infection and immunity
Xu SX,Gilmore KJ,Szabo PA,Zeppa JJ,Baroja ML,Haeryfar SM,McCormick JK
11-5931 was used in Flow cytometry/Cell sorting to study host immune responses to superantigen toxins released by S. aureus.
Mon Sep 01 00:00:00 EDT 2014
Anti-tumor innate immunity activated by intermittent metronomic cyclophosphamide treatment of 9L brain tumor xenografts is preserved by anti-angiogenic drugs that spare VEGF receptor 2.
Molecular cancer
Doloff JC,Chen CS,Waxman DJ
11-5931 was used in Flow cytometry/Cell sorting to investigate the variation in immune response from different regimens of metronomic cyclophosphamide treatment.
Thu Jun 26 00:00:00 EDT 2014
Activation of NLRP3 inflammasome by crystalline structures via cell surface contact.
Scientific reports
Hari A,Zhang Y,Tu Z,Detampel P,Stenner M,Ganguly A,Shi Y
11-5931 was used in Flow cytometry/Cell sorting to show that potassium efflux, but not cathepsin B release from the ruptured lysosome, is required for crystal-mediated NLRP3 inflammasome activation and production of IL-β.
Tue Dec 02 00:00:00 EST 2014
IKKα negatively regulates ASC-dependent inflammasome activation.
Nature communications
Martin BN,Wang C,Willette-Brown J,Herjan T,Gulen MF,Zhou H,Bulek K,Franchi L,Sato T,Alnemri ES,Narla G,Zhong XP,Thomas J,Klinman D,Fitzgerald KA,Karin M,Nuñez G,Dubyak G,Hu Y,Li X
11-5931 was used in Flow cytometry/Cell sorting to investigate the role of IκB kinase α in inflammasome activation, showing that it negatively regulates ASC-dependent activation.
Tue Sep 30 00:00:00 EDT 2014
Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration.
Nature medicine
Lucas D,Scheiermann C,Chow A,Kunisaki Y,Bruns I,Barrick C,Tessarollo L,Frenette PS
11-5931 was used in Flow cytometry/Cell sorting to demonstrate the potential benefit of adrenergic nerve protection for shielding hematopoietic niches from injury.
Sat Jun 01 00:00:00 EDT 2013
Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration.
Nature medicine
Lucas D,Scheiermann C,Chow A,Kunisaki Y,Bruns I,Barrick C,Tessarollo L,Frenette PS
11-5931 was used in Flow cytometry/Cell sorting to demonstrate the potential benefit of adrenergic nerve protection for shielding hematopoietic niches from injury.
Sat Jun 01 00:00:00 EDT 2013
Structure and function of the Salmonella Typhi chimaeric A(2)B(5) typhoid toxin.
Nature
Song J,Gao X,Galán JE
11-5931 was used in Flow cytometry/Cell sorting to study the structure and pathogenicity of typhoid toxin, a unique virulence factor of Salmonella Typhi.
Thu Jul 18 00:00:00 EDT 2013
Aspirin-triggered resolvin D1 reduces mucosal inflammation and promotes resolution in a murine model of acute lung injury.
Mucosal immunology
Eickmeier O,Seki H,Haworth O,Hilberath JN,Gao F,Uddin M,Croze RH,Carlo T,Pfeffer MA,Levy BD
11-5931 was used in Flow cytometry/Cell sorting to study the effects of aspirin-triggered resolvin D1 on mucosal injury in a murine model of acute lung injury.
Fri Mar 01 00:00:00 EST 2013
Distinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells.
Development (Cambridge, England)
Tober J,Yzaguirre AD,Piwarzyk E,Speck NA
11-5931 was used in Flow cytometry/Cell sorting to study how the requirements for Runx1 in erythroid/myeloid progenitors and hematopoietic stem cell formation are temporally distinct.
Sun Sep 01 00:00:00 EDT 2013
Low-dose cyclophosphamide administered as daily or single dose enhances the antitumor effects of a therapeutic HPV vaccine.
Cancer immunology, immunotherapy : CII
Peng S,Lyford-Pike S,Akpeng B,Wu A,Hung CF,Hannaman D,Saunders JR,Wu TC,Pai SI
11-5931 was used in Flow cytometry/Cell sorting to demonstrate a decreased vaccine-induced CD8(+) T-cell frequency after administration of CTX.
Tue Jan 01 00:00:00 EST 2013
A new immuno-, dystrophin-deficient model, the NSG-mdx(4Cv) mouse, provides evidence for functional improvement following allogeneic satellite cell transplantation.
Stem cells (Dayton, Ohio)
Arpke RW,Darabi R,Mader TL,Zhang Y,Toyama A,Lonetree CL,Nash N,Lowe DA,Perlingeiro RC,Kyba M
11-5931 was used in Flow cytometry/Cell sorting to highlight the potency of satellite cells to improve muscle function and the utility of the NSG-mdx(4Cv) model for studies on muscle regeneration.
Thu Aug 01 00:00:00 EDT 2013
Reduced neutrophil chemotaxis and infiltration contributes to delayed resolution of cutaneous wound infection with advanced age.
Journal of immunology (Baltimore, Md. : 1950)
Brubaker AL,Rendon JL,Ramirez L,Choudhry MA,Kovacs EJ
11-5931 was used in Flow cytometry/Cell sorting to deduce the contribution of reduced neutrophil chemotaxis and infiltration to the speed of wound infection healing.
Fri Feb 15 00:00:00 EST 2013
A pathogenic role for CD4+ T cells during Chikungunya virus infection in mice.
Journal of immunology (Baltimore, Md. : 1950)
Teo TH,Lum FM,Claser C,Lulla V,Lulla A,Merits A,Rénia L,Ng LF
11-5931 was used in Flow cytometry/Cell sorting to assess the roles of T cells in Chikungunya virus infection using immunodeficient mice.
Tue Jan 01 00:00:00 EST 2013
Ganciclovir prophylaxis improves late murine cytomegalovirus-induced renal allograft damage.
Transplantation
Shimamura M,Seleme MC,Guo L,Saunders U,Schoeb TR,George JF,Britt WJ
11-5931 was used in Flow cytometry/Cell sorting to examine the lasting effect of Ganciclovir treatment on renal allografts after the discontinuation of prophylaxis.
Tue Jan 15 00:00:00 EST 2013
Uterine natural killer cells severely decrease in number at gestation day 6 in mice.
Biology of reproduction
Takashima A,Ishikawa F,Kuwabara T,Tanaka Y,Kinoshita T,Ito M,Kakiuchi T
11-5931 was used in Flow cytometry/Cell sorting to study how uterine NK cells or their precursors migrate into the uterus, mature, and produce interferon-gamma to support pregnancy in mice.
Tue Oct 01 00:00:00 EDT 2013
G-CSF enhances resolution of Staphylococcus aureus wound infection in an age-dependent manner.
Shock (Augusta, Ga.)
Brubaker AL,Kovacs EJ
11-5931 was used in Flow cytometry/Cell sorting to demonstrate that G-CSF enhances bacterial clearance and wound closure in an age-dependent manner.
Tue Oct 01 00:00:00 EDT 2013
The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects.
The Journal of biological chemistry
Zamanian-Daryoush M,Lindner D,Tallant TC,Wang Z,Buffa J,Klipfell E,Parker Y,Hatala D,Parsons-Wingerter P,Rayman P,Yusufishaq MSS,Fisher EA,Smith JD,Finke J,DiDonato JA,Hazen SL
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Fri Jul 19 00:00:00 EDT 2013
A novel probe for the non-invasive detection of tumor-associated inflammation.
Oncoimmunology
Balducci A,Wen Y,Zhang Y,Helfer BM,Hitchens TK,Meng WS,Wesa AK,Janjic JM
11-5931 was used in Flow cytometry/Cell sorting to develop a novel probe for the non-invasive detection of tumor-associated inflammation, with its feasibility demonstrated in a murine breast carcinoma model.
Fri Feb 01 00:00:00 EST 2013
Absence of CCR5 increases neutrophil recruitment in severe herpetic encephalitis.
BMC neuroscience
Vilela MC,Lima GK,Rodrigues DH,Lacerda-Queiroz N,Pedroso VS,Miranda AS,Rachid MA,Kroon EG,Campos MA,Teixeira MM,Sellner J,Teixeira AL
11-5931 was used in Flow cytometry/Cell sorting to evaluate the role of CCR5 on traffic of leukocytes in the brain microvasculature, cellular and cytokines profiles in a severe form of herpetic encephalitis.
Thu Feb 07 00:00:00 EST 2013
Partial depletion of regulatory T cells does not influence the inflammation caused by high dose hemi-body irradiation.
PloS one
Ma S,Richardson JA,Bitmansour A,Solberg TD,Pidikiti R,Song K,Stojadinovic S,Vitetta ES,Meyer JJ
11-5931 was used in Flow cytometry/Cell sorting to investigate the effects of partial depletion of regulatory T cells alongside ionizing radiation on inflammation and tissue injury in mice.
Mon Jul 29 00:00:00 EDT 2013
PI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4β1, leading to tumor inflammation and growth.
PloS one
Schmid MC,Franco I,Kang SW,Hirsch E,Quilliam LA,Varner JA
11-5931 was used in Flow cytometry/Cell sorting to suggest novel avenues for cancer therapy by manipulating the PI3Kγ-Rap1a-dependent pathway.
Wed Oct 30 00:00:00 EDT 2013
Resistance to Streptozotocin-Induced Autoimmune Diabetes in Absence of Complement C3: Myeloid-Derived Suppressor Cells Play a Role.
PloS one
Gao X,Liu H,He B,Fu Z
11-5931 was used in Flow cytometry/Cell sorting to indicate that myeloid-derived suppressor cells are implicated in resistance to STZ-induced diabetes in the absence of complement C3 in mice.
Fri Oct 13 00:00:00 EDT 2017
R-spondin 2 signalling mediates susceptibility to fatal infectious diarrhoea.
Nature communications
Papapietro O,Teatero S,Thanabalasuriar A,Yuki KE,Diez E,Zhu L,Kang E,Dhillon S,Muise AM,Durocher Y,Marcinkiewicz MM,Malo D,Gruenheid S
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in In Situ Hybridization (ISH)
Mon Dec 30 00:00:00 EST 2013
G-CSF/anti-G-CSF antibody complexes drive the potent recovery and expansion of CD11b+Gr-1+ myeloid cells without compromising CD8+ T cell immune responses.
Journal of hematology & oncology
Rubinstein MP,Salem ML,Doedens AL,Moore CJ,Chiuzan C,Rivell GL,Cole DJ,Goldrath AW
11-5931 was used in Flow cytometry/Cell sorting to evaluate whether the biological activity of G-CSF can be improved by pre-association with anti-G-CSF monoclonal antibodies prior to injection.
Tue Oct 01 00:00:00 EDT 2013
Depletion of regulatory T cells in a mouse experimental glioma model through anti-CD25 treatment results in the infiltration of non-immunosuppressive myeloid cells in the brain.
Clinical & developmental immunology
Maes W,Verschuere T,Van Hoylandt A,Boon L,Van Gool S
11-5931 was used in Flow cytometry/Cell sorting to evaluate the local elimination of Tregs as a tool for augmentation of the antitumoural response.
Tue Dec 10 00:00:00 EST 2013
Elimination of Aspergillus fumigatus conidia from the airways of mice with allergic airway inflammation.
Respiratory research
Shevchenko MA,Bolkhovitina EL,Servuli EA,Sapozhnikov AM
11-5931 was used in Immunohistochemistry to show allergen aspiration in sensitized mice enhances the ingestion potential of airway neutrophils to control non-germinating A. fumigatus conidia dissemination.
Sat Jul 27 00:00:00 EDT 2013
γδ T cells recognize a microbial encoded B cell antigen to initiate a rapid antigen-specific interleukin-17 response.
Immunity
Zeng X,Wei YL,Huang J,Newell EW,Yu H,Kidd BA,Kuhns MS,Waters RW,Davis MM,Weaver CT,Chien YH
11-5931 was used in Flow cytometry/Cell sorting to study the γδ T cell response to the algae protein, phycoerythrin.
Fri Sep 21 00:00:00 EDT 2012
Transcription factor RORα is critical for nuocyte development.
Nature immunology
Wong SH,Walker JA,Jolin HE,Drynan LF,Hams E,Camelo A,Barlow JL,Neill DR,Panova V,Koch U,Radtke F,Hardman CS,Hwang YY,Fallon PG,McKenzie AN
11-5931 was used in Flow cytometry/Cell sorting to study how nuocytes arose in the bone marrow and differentiated from common lymphoid progenitors, indicating they are a distinct, previously unknown member of the lymphoid lineage.
Sun Jan 22 00:00:00 EST 2012
IFNγ induces monopoiesis and inhibits neutrophil development during inflammation.
Blood
de Bruin AM,Libregts SF,Valkhof M,Boon L,Touw IP,Nolte MA
11-5931 was used in Flow cytometry/Cell sorting to demonstrate that the pro-inflammatory cytokine IFNγ is involved in orchestrating inflammation-induced myelopoiesis.
Thu Feb 09 00:00:00 EST 2012
Ionizing radiation-induced expression of INK4a/ARF in murine bone marrow-derived stromal cell populations interferes with bone marrow homeostasis.
Blood
Carbonneau CL,Despars G,Rojas-Sutterlin S,Fortin A,Le O,Hoang T,Beauséjour CM
11-5931 was used in Flow cytometry/Cell sorting to investigate the effect of ionizing radiation on murine bone marrow-derived stromal cell populations, and overall bone marrow homeostasis.
Thu Jan 19 00:00:00 EST 2012
VEGF-A recruits a proangiogenic MMP-9-delivering neutrophil subset that induces angiogenesis in transplanted hypoxic tissue.
Blood
Christoffersson G,Vågesjö E,Vandooren J,Lidén M,Massena S,Reinert RB,Brissova M,Powers AC,Opdenakker G,Phillipson M
11-5931 was used in Flow cytometry/Cell sorting to delineate the mechanisms underlying leukocyte recruitment to, and actions at, sites of angiogenesis.
Thu Nov 29 00:00:00 EST 2012
N-cadherin in osteolineage cells is not required for maintenance of hematopoietic stem cells.
Blood
Greenbaum AM,Revollo LD,Woloszynek JR,Civitelli R,Link DC
11-5931 was used in Flow cytometry/Cell sorting to investigate whether N-cadherin expression on osteoblast lineage cells regulates HSC function and quiescence, showing that it is not required.
Thu Jul 12 00:00:00 EDT 2012
Concomitant inactivation of Rb and E2f8 in hematopoietic stem cells synergizes to induce severe anemia.
Blood
Hu T,Ghazaryan S,Sy C,Wiedmeyer C,Chang V,Wu L
11-5931 was used in Flow cytometry/Cell sorting to reveal the specificity of E2F8 in mediating Rb function in erythropoiesis.
Thu May 10 00:00:00 EDT 2012
Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis.
The Journal of clinical investigation
Jamieson T,Clarke M,Steele CW,Samuel MS,Neumann J,Jung A,Huels D,Olson MF,Das S,Nibbs RJ,Sansom OJ
11-5931 was used in Flow cytometry/Cell sorting to show that CXCR2 is a potent protumourigenic chemokine receptor directs recruitment of tumour-promoting leukocytes into tissues during tumour-inducing and driven inflammation.
Sat Sep 01 00:00:00 EDT 2012
Cathepsin K deficiency reduces elastase perfusion-induced abdominal aortic aneurysms in mice.
Arteriosclerosis, thrombosis, and vascular biology
Sun J,Sukhova GK,Zhang J,Chen H,Sjöberg S,Libby P,Xia M,Xiong N,Gelb BD,Shi GP
11-5931 was used in Flow cytometry/Cell sorting to study the role of cathepsin K in abdominal aortic aneurysms.
Sun Jan 01 00:00:00 EST 2012
Annexin A1 regulates neutrophil clearance by macrophages in the mouse bone marrow.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Dalli J,Jones CP,Cavalcanti DM,Farsky SH,Perretti M,Rankin SM
11-5931 was used in Flow cytometry/Cell sorting to identify a role of the anti-inflammatory molecule annexin A1 in the regulation of CXCR4(hi) neutrophil migration to bone marrow.
Sun Jan 01 00:00:00 EST 2012
The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis.
The American journal of pathology
Piliponsky AM,Chen CC,Rios EJ,Treuting PM,Lahiri A,Abrink M,Pejler G,Tsai M,Galli SJ
11-5931 was used in Flow cytometry/Cell sorting to investigate the role of chymase mouse mast cell protease 4 in a mouse model of sepsis.
Sat Sep 01 00:00:00 EDT 2012
Staphylococcus aureus induces type I IFN signaling in dendritic cells via TLR9.
Journal of immunology (Baltimore, Md. : 1950)
Parker D,Prince A
11-5931 was used in Flow cytometry/Cell sorting to illustrate an additional mechanism through which S. aureus exploits innate immune signalling to facilitate infection.
Mon Oct 15 00:00:00 EDT 2012
In vivo imaging of differences in early donor cell proliferation in graft-versus-host disease hosts with different pre-conditioning doses.
Molecules and cells
Song MG,Kang B,Jeon JY,Chang J,Lee S,Min CK,Youn H,Choi EY
11-5931 was used in Flow cytometry/Cell sorting to explore the effects of preconditioning irradiation doses on donor cell dynamics in allogeneic graft-versus-host disease hosts.
Sun Jan 01 00:00:00 EST 2012
Differential gene expression in mice infected with distinct Toxoplasma strains.
Infection and immunity
Hill RD,Gouffon JS,Saxton AM,Su C
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2012
A model of GAG/MIP-2/CXCR2 interfaces and its functional effects.
Biochemistry
Rajasekaran D,Keeler C,Syed MA,Jones MC,Harrison JK,Wu D,Bhandari V,Hodsdon ME,Lolis EJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Tue Jul 17 00:00:00 EDT 2012
Virotherapy of canine tumors with oncolytic vaccinia virus GLV-1h109 expressing an anti-VEGF single-chain antibody.
PloS one
Patil SS,Gentschev I,Adelfinger M,Donat U,Hess M,Weibel S,Nolte I,Frentzen A,Szalay AA
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Thu Mar 28 00:00:00 EDT 2013
In vivo inhibition of c-MYC in myeloid cells impairs tumor-associated macrophage maturation and pro-tumoral activities.
PloS one
Pello OM,Chèvre R,Laoui D,De Juan A,Lolo F,Andrés-Manzano MJ,Serrano M,Van Ginderachter JA,Andrés V
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Mon Feb 25 00:00:00 EST 2013
Impact of intravenous immunoglobulin on the dopaminergic system and immune response in the acute MPTP mouse model of Parkinson's disease.
Journal of neuroinflammation
St-Amour I,Bousquet M,Paré I,Drouin-Ouellet J,Cicchetti F,Bazin R,Calon F
11-5931 was used in Flow cytometry/Cell sorting to investigate the potential neurorestorative effect of IVIg treatment in mice.
Tue Oct 09 00:00:00 EDT 2012
Preclinical evaluation of oncolytic vaccinia virus for therapy of canine soft tissue sarcoma.
PloS one
Gentschev I,Adelfinger M,Josupeit R,Rudolph S,Ehrig K,Donat U,Weibel S,Chen NG,Yu YA,Zhang Q,Heisig M,Thamm D,Stritzker J,Macneill A,Szalay AA
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunofluorescence
Thu Sep 20 00:00:00 EDT 2012
Oncogenic Kras expression in postmitotic neurons leads to S100A8-S100A9 protein overexpression and gliosis.
The Journal of biological chemistry
Ryu MJ,Liu Y,Zhong X,Du J,Peterson N,Kong G,Li H,Wang J,Salamat S,Chang Q,Zhang J
11-5931 was used in Flow cytometry/Cell sorting to determine how Ras signalling in neurones promotes gliosis and astrocytoma formation in a cell nonautonomous manner.
Fri Jun 29 00:00:00 EDT 2012
Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment.
Cell communication and signaling : CCS
Wiechert L,Németh J,Pusterla T,Bauer C,De Ponti A,Manthey S,Marhenke S,Vogel A,Klingmüller U,Hess J,Angel P
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunohistochemistry
Sat Dec 15 00:00:00 EST 2012
Galectin-9 attenuates acute lung injury by expanding CD14- plasmacytoid dendritic cell-like macrophages.
American journal of respiratory and critical care medicine
Kojima K,Arikawa T,Saita N,Goto E,Tsumura S,Tanaka R,Masunaga A,Niki T,Oomizu S,Hirashima M,Kohrogi H
11-5931 was used in Flow cytometry/Cell sorting to study how Gal-9 attenuates ALI by expanding CD14(-)CD11b(+)Gr-1(+) pDC-like macrophages by preferentially suppressing macrophage functions.
Mon Aug 01 00:00:00 EDT 2011
Genetic deletion of chemokine receptor Ccr6 decreases atherogenesis in ApoE-deficient mice.
Circulation research
Wan W,Lim JK,Lionakis MS,Rivollier A,McDermott DH,Kelsall BL,Farber JM,Murphy PM
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Fri Aug 05 00:00:00 EDT 2011
Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice.
The Journal of clinical investigation
Maniati E,Bossard M,Cook N,Candido JB,Emami-Shahri N,Nedospasov SA,Balkwill FR,Tuveson DA,Hagemann T
11-5931 was used in Flow cytometry/Cell sorting to reveal a novel interaction between oncogenic inflammation and the NF-κB pathway.
Thu Dec 01 00:00:00 EST 2011
Th2 signals induce epithelial injury in mice and are compatible with the biliary atresia phenotype.
The Journal of clinical investigation
Li J,Bessho K,Shivakumar P,Mourya R,Mohanty SK,Dos Santos JL,Miura IK,Porta G,Bezerra JA
11-5931 was used in Flow cytometry/Cell sorting to assess whether Th1-independent mechanisms can activate effector cells to induce biliary atresia.
Tue Nov 01 00:00:00 EDT 2011
Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice.
The Journal of experimental medicine
Christopher MJ,Rao M,Liu F,Woloszynek JR,Link DC
11-5931 was used in Flow cytometry/Cell sorting to suggest a model in which G-CSFR signals in bone marrow monocytic cells inhibit the production of trophic factors required for osteoblast lineage cell maintenance.
Mon Feb 14 00:00:00 EST 2011
Combined blockade of integrin-α4β1 plus cytokines SDF-1α or IL-1β potently inhibits tumor inflammation and growth.
Cancer research
Schmid MC,Avraamides CJ,Foubert P,Shaked Y,Kang SW,Kerbel RS,Varner JA
11-5931 was used in Flow cytometry/Cell sorting to show that stromal cell-derived growth factor 1 alpha and interleukin 1 beta collaborate with myeloid cell integrin-α4β1 to promote tumor inflammation and growth.
Tue Nov 15 00:00:00 EST 2011
Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1α.
Proceedings of the National Academy of Sciences of the United States of America
Berda-Haddad Y,Robert S,Salers P,Zekraoui L,Farnarier C,Dinarello CA,Dignat-George F,Kaplanski G
11-5931-82 was used in Flow Cytometry to demonstrate that nonphagocytosed endothelial apoptotic bodies constitute a unique mechanism for sterile inflammation.
Tue Dec 20 00:00:00 EST 2011
Morphological plasticity promotes resistance to phagocyte killing of uropathogenic Escherichia coli.
Microbes and infection
Horvath DJ,Li B,Casper T,Partida-Sanchez S,Hunstad DA,Hultgren SJ,Justice SS
11-5931 was used in Flow cytometry/Cell sorting to demonstrate that SulA-mediated filamentation in UPEC provides a selective advantage in evading phagocytic killing, and represents a distinct class of mechanism for subverting host immunity.
Sun May 01 00:00:00 EDT 2011
Elevated epidermal ornithine decarboxylase activity suppresses contact hypersensitivity.
The Journal of investigative dermatology
Keough MP,Hayes CS,DeFeo K,Gilmour SK
11-5931 was used in Flow cytometry/Cell sorting to suggest that the immunosuppression promoted by increased epidermal ODC is mediated by a reduction in cytokine levels, which suppresses DC migration and reduces immune cell infiltration to the site of hapten application.
Sat Jan 01 00:00:00 EST 2011
A tritherapy combination of a fusion protein vaccine with immune-modulating doses of sequential chemotherapies in an optimized regimen completely eradicates large tumors in mice.
International journal of cancer
Song X,Guo W,Cui J,Qian X,Yi L,Chang M,Cai Q,Zhao Q
11-5931 was used in Flow cytometry/Cell sorting to study the immune-modulating doses of sequential chemoimmunotherapeutic strategy targeting not only the tumour but also its microenvironment.
Tue Mar 01 00:00:00 EST 2011
Important role of neutrophils in the late asthmatic response in mice.
Life sciences
Nabe T,Hosokawa F,Matsuya K,Morishita T,Ikedo A,Fujii M,Mizutani N,Yoshino S,Chaplin DD
11-5931 was used in Flow cytometry/Cell sorting to determine whether neutrophils are involved in the late asthmatic response, and to analyse mechanisms underlying the antigen-induced airway neutrophilia.
Mon Jun 20 00:00:00 EDT 2011
Effects of Pre-conditioning Dose on the Immune Kinetics and Cytokine Production in the Leukocytes Infiltrating GVHD Tissues after MHC-matched Transplantation.
Immune network
Choi JH,Yoon H,Min CK,Choi EY
11-5931 was used in Flow cytometry/Cell sorting to analyse chimerism formation and immune kinetics of leukocytes during graft-versus-host disease.
Tue Feb 01 00:00:00 EST 2011
Endogenous galectin-1 and acute inflammation: emerging notion of a galectin-9 pro-resolving effect.
The American journal of pathology
Iqbal AJ,Sampaio AL,Maione F,Greco KV,Niki T,Hirashima M,Perretti M,Cooper D
11-5931 was used in Flow cytometry/Cell sorting to show that the absence of endogenous Gal-1 results in an abrogated response during the second phase of the edema reaction.
Tue Mar 01 00:00:00 EST 2011
The melanocortin agonist AP214 exerts anti-inflammatory and proresolving properties.
The American journal of pathology
Montero-Melendez T,Patel HB,Seed M,Nielsen S,Jonassen TE,Perretti M
11-5931 was used in Flow cytometry/Cell sorting to characterise receptor involvement in melanocortin-mediated inhibition of inflammation and tissue injury.
Fri Jul 01 00:00:00 EDT 2011
MMP9 is protective against lethal inflammatory mass lesions in the mouse colon.
Disease models & mechanisms
Hald A,Rønø B,Melander MC,Ding M,Holck S,Lund LR
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunohistochemistry
Tue Mar 01 00:00:00 EST 2011
Hydrodynamic delivery of human IL-15 cDNA increases murine natural killer cell recovery after syngeneic bone marrow transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
Barao I,Alvarez M,Redelman D,Weiss JM,Ortaldo JR,Wiltrout RH,Murphy WJ
11-5931 was used in Flow cytometry/Cell sorting to highlight cytokine gene transfer-based methods as a potential platform for natural killer cell recovery after bone marrow transplantation in mice.
Thu Dec 01 00:00:00 EST 2011
Exacerbated experimental autoimmune encephalomyelitis in mast-cell-deficient Kit W-sh/W-sh mice.
Laboratory investigation; a journal of technical methods and pathology
Piconese S,Costanza M,Musio S,Tripodo C,Poliani PL,Gri G,Burocchi A,Pittoni P,Gorzanelli A,Colombo MP,Pedotti R
11-5931 was used in Flow cytometry/Cell sorting to investigate the potential detrimental role of mast cells in experimental autoimmune encephalomyelitis.
Fri Apr 01 00:00:00 EDT 2011
Evidence for an anti-inflammatory loop centered on polymorphonuclear leukocyte formyl peptide receptor 2/lipoxin A4 receptor and operative in the inflamed microvasculature.
Journal of immunology (Baltimore, Md. : 1950)
Brancaleone V,Dalli J,Bena S,Flower RJ,Cirino G,Perretti M
11-5931 was used in Flow cytometry/Cell sorting to propose the existence of an endogenous network in anti-inflammation centered on PMN AnxA1 and activated by selective FPR2/ALX agonists.
Fri Apr 15 00:00:00 EDT 2011
Genetic variation determines mast cell functions in experimental asthma.
Journal of immunology (Baltimore, Md. : 1950)
Becker M,Reuter S,Friedrich P,Doener F,Michel A,Bopp T,Klein M,Schmitt E,Schild H,Radsak MP,Echtenacher B,Taube C,Stassen M
11-5931 was used in Flow cytometry/Cell sorting to investigate the role of mast cells in allergic asthma.
Wed Jun 15 00:00:00 EDT 2011
Effect of topical azithromycin on corneal innate immune responses.
Investigative ophthalmology & visual science
Sadrai Z,Hajrasouliha AR,Chauhan S,Saban DR,Dastjerdi MH,Dana R
11-5931 was used in Flow cytometry/Cell sorting to suggest topical azithromycin may have an anti-inflammatory effect on corneal inflammation in a murine model.
Tue Apr 19 00:00:00 EDT 2011
Interleukin-17 contributes to generation of Th1 immunity and neutrophil recruitment during Chlamydia muridarum genital tract infection but is not required for macrophage influx or normal resolution of infection.
Infection and immunity
Scurlock AM,Frazer LC,Andrews CW,O'Connell CM,Foote IP,Bailey SL,Chandra-Kuntal K,Kolls JK,Darville T
11-5931 was used in Flow cytometry/Cell sorting to investigate the role of IL-17 during C. muridarum genital tract infection.
Tue Mar 01 00:00:00 EST 2011
Prevention of NKT cell activation accelerates cutaneous wound closure and alters local inflammatory signals.
The Journal of surgical research
Schneider DF,Palmer JL,Tulley JM,Kovacs EJ,Gamelli RL,Faunce DE
11-5931 was used in Flow cytometry/Cell sorting to explore the effects of purposefully inhibiting natural killer T cell activation on the response to injury.
Tue Nov 01 00:00:00 EDT 2011
An improved cell isolation method for flow cytometric and functional analyses of cutaneous wound leukocytes.
Journal of immunological methods
Brubaker AL,Schneider DF,Palmer JL,Faunce DE,Kovacs EJ
11-5931 was used in Flow cytometry/Cell sorting to develop a method for preparing wound cell suspensions for further study.
Fri Oct 28 00:00:00 EDT 2011
Pseudomonas aeruginosa elastase provides an escape from phagocytosis by degrading the pulmonary surfactant protein-A.
PloS one
Kuang Z,Hao Y,Walling BE,Jeffries JL,Ohman DE,Lau GW
11-5931 was used in Flow cytometry/Cell sorting to study how P. aeruginosa secretions grant protection against SP-A-mediated opsonisation.
Fri Mar 16 00:00:00 EDT 2012
Novel proresolving aspirin-triggered DHA pathway.
Chemistry & biology
Serhan CN,Fredman G,Yang R,Karamnov S,Belayev LS,Bazan NG,Zhu M,Winkler JW,Petasis NA
11-5931 was used in Flow cytometry/Cell sorting to investigate endogenous mechanisms of the resolution of acute inflammation, showing a novel proresolving aspirin-triggered DHA pathway.
Fri Aug 26 00:00:00 EDT 2011
Intracerebral infection with dengue-3 virus induces meningoencephalitis and behavioral changes that precede lethality in mice.
Journal of neuroinflammation
Amaral DC,Rachid MA,Vilela MC,Campos RD,Ferreira GP,Rodrigues DH,Lacerda-Queiroz N,Miranda AS,Costa VV,Campos MA,Kroon EG,Teixeira MM,Teixeira AL
11-5931 was used in Flow cytometry/Cell sorting to evaluate the trafficking of leukocytes in brain microvasculature.
Wed Mar 09 00:00:00 EST 2011
Study of camelpox virus pathogenesis in athymic nude mice.
PloS one
Duraffour S,Matthys P,van den Oord JJ,De Schutter T,Mitera T,Snoeck R,Andrei G
11-5931 was used in Flow cytometry/Cell sorting to confirm that NMRI immunocompetent mice are resistant to intranasal (i.n.) CMLV infection.
Thu Dec 01 00:00:00 EST 2011
Local mesenchymal stem/progenitor cells are a preferential target for initiation of adult soft tissue sarcomas associated with p53 and Rb deficiency.
The American journal of pathology
Choi J,Curtis SJ,Roy DM,Flesken-Nikitin A,Nikitin AY
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2010
Local mesenchymal stem/progenitor cells are a preferential target for initiation of adult soft tissue sarcomas associated with p53 and Rb deficiency.
The American journal of pathology
Choi J,Curtis SJ,Roy DM,Flesken-Nikitin A,Nikitin AY
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2010
Mast cell-derived TNF can exacerbate mortality during severe bacterial infections in C57BL/6-KitW-sh/W-sh mice.
The American journal of pathology
Piliponsky AM,Chen CC,Grimbaldeston MA,Burns-Guydish SM,Hardy J,Kalesnikoff J,Contag CH,Tsai M,Galli SJ
11-5931 was used in Flow cytometry/Cell sorting to investigate the roles of mast cells and their derived proteins in two models of severe bacterial infection.
Mon Feb 01 00:00:00 EST 2010
Ability of IDO to attenuate liver injury in alpha-galactosylceramide-induced hepatitis model.
Journal of immunology (Baltimore, Md. : 1950)
Ito H,Hoshi M,Ohtaki H,Taguchi A,Ando K,Ishikawa T,Osawa Y,Hara A,Moriwaki H,Saito K,Seishima M
11-5931 was used in Flow cytometry/Cell sorting to study the immunological effects of IDO in α-galactosylceramide (α-GalCer)-induced hepatitis.
Fri Oct 15 00:00:00 EDT 2010
The presence of professional phagocytes dictates the number of host cells targeted for Yop translocation during infection.
Cellular microbiology
Durand EA,Maldonado-Arocho FJ,Castillo C,Walsh RL,Mecsas J
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunofluorescence
Sun Aug 01 00:00:00 EDT 2010
The presence of professional phagocytes dictates the number of host cells targeted for Yop translocation during infection.
Cellular microbiology
Durand EA,Maldonado-Arocho FJ,Castillo C,Walsh RL,Mecsas J
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunofluorescence
Sun Aug 01 00:00:00 EDT 2010
Regulatory T cells suppress innate immunity in kidney ischemia-reperfusion injury.
Journal of the American Society of Nephrology : JASN
Kinsey GR,Sharma R,Huang L,Li L,Vergis AL,Ye H,Ju ST,Okusa MD
11-5931 was used in Flow cytometry/Cell sorting to investigate whether the anti-inflammatory effects of CD4(+)CD25(+)FoxP3(+) Tregs protect against renal IRI.
Sat Aug 01 00:00:00 EDT 2009
The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies.
Cancer research
Ozao-Choy J,Ma G,Kao J,Wang GX,Meseck M,Sung M,Schwartz M,Divino CM,Pan PY,Chen SH
11-5931 was used in Flow cytometry/Cell sorting to suggest that sunitinib can be used to reverse immune suppression and as a potentially useful adjunct for enhancing the efficacy of immune-based cancer therapy for advanced malignancies.
Sun Mar 15 00:00:00 EDT 2009
Combination of all-trans retinoic acid and a human papillomavirus therapeutic vaccine suppresses the number and function of immature myeloid cells and enhances antitumor immunity.
Cancer science
Song X,Ye D,Liu B,Cui J,Zhao X,Yi L,Liang J,Song J,Zhang Z,Zhao Q
11-5931-82 was used in Flow Cytometry to suggest potential clinical benefits for the combined use of ATRA and HPV therapeutic vaccines.
Sun Feb 01 00:00:00 EST 2009
c-Myb is required for pro-B cell differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Fahl SP,Crittenden RB,Allman D,Bender TP
11-5931 was used in Flow cytometry/Cell sorting to demonstrate that c-Myb is absolutely required for the survival and differentiation of CD19(+) B-lineage cells.
Sun Nov 01 00:00:00 EDT 2009
Hypercostimulation through 4-1BB distorts homeostasis of immune cells.
Journal of immunology (Baltimore, Md. : 1950)
Lee SW,Salek-Ardakani S,Mittler RS,Croft M
11-5931 was used in Flow cytometry/Cell sorting to investigate the potential side effects of immunotherapeutic strategies using Abs against costimulatory molecules.
Mon Jun 01 00:00:00 EDT 2009
Regulation of mature ADAM17 by redox agents for L-selectin shedding.
Journal of immunology (Baltimore, Md. : 1950)
Wang Y,Herrera AH,Li Y,Belani KK,Walcheck B
11-5931 was used in Flow cytometry/Cell sorting to investigate the target of induced ADAM17 in neutrophils.
Sun Feb 15 00:00:00 EST 2009
Treatment with LL-37 peptide enhances antitumor effects induced by CpG oligodeoxynucleotides against ovarian cancer.
Human gene therapy
Chuang CM,Monie A,Wu A,Mao CP,Hung CF
11-5931 was used in Flow cytometry/Cell sorting to demonstrate the potential of combined CpG-ODN-LL-37 peptide treatment for the control of ovarian tumours.
Wed Apr 01 00:00:00 EDT 2009
TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.
Cellular immunology
Drage MG,Pecora ND,Hise AG,Febbraio M,Silverstein RL,Golenbock DT,Boom WH,Harding CV
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Fri Jun 12 00:00:00 EDT 2009
IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response.
Blood
Rubinstein MP,Lind NA,Purton JF,Filippou P,Best JA,McGhee PA,Surh CD,Goldrath AW
11-5931 was used in Flow cytometry/Cell sorting to study IL-7 and IL-15 regulation of CD8+ T-cell subsets during contraction of the immune response.
Sat Nov 01 00:00:00 EDT 2008
Decreased inflammatory response in Toll-like receptor 2 knockout mice is associated with exacerbated Pneumocystis pneumonia.
Microbes and infection
Wang SH,Zhang C,Lasbury ME,Liao CP,Durant PJ,Tschang D,Lee CH
11-5931 was used in Flow cytometry/Cell sorting to show that TLR2-mediated inflammatory responses contribute to the clearance of Pneumocystis.
Tue Apr 01 00:00:00 EDT 2008
IL-7 specifies B cell fate at the common lymphoid progenitor to pre-proB transition stage by maintaining early B cell factor expression.
Journal of immunology (Baltimore, Md. : 1950)
Kikuchi K,Kasai H,Watanabe A,Lai AY,Kondo M
11-5931 was used in Flow cytometry/Cell sorting to investigate when IL-7 stimulation is necessary in hemato-/lymphopoiesis in adult mice, showing that IL-7 specifies B cell fate at the common lymphoid progenitor to pre-proB transition stage by maintaining early B cell factor expression.
Tue Jul 01 00:00:00 EDT 2008
Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Drake PM,Nathan JK,Stock CM,Chang PV,Muench MO,Nakata D,Reader JR,Gip P,Golden KP,Weinhold B,Gerardy-Schahn R,Troy FA,Bertozzi CR
11-5931 was used in Flow cytometry/Cell sorting to investigate the expression and possible function of polysialic acid in the immune system.
Sat Nov 15 00:00:00 EST 2008
Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Drake PM,Nathan JK,Stock CM,Chang PV,Muench MO,Nakata D,Reader JR,Gip P,Golden KP,Weinhold B,Gerardy-Schahn R,Troy FA,Bertozzi CR
11-5931 was used in Flow cytometry/Cell sorting to investigate the expression and possible function of polysialic acid in the immune system.
Sat Nov 15 00:00:00 EST 2008
Runx proteins are involved in regulation of CD122, Ly49 family and IFN-gamma expression during NK cell differentiation.
International immunology
Ohno S,Sato T,Kohu K,Takeda K,Okumura K,Satake M,Habu S
11-5931 was used in Flow cytometry/Cell sorting to investigate the role of Runx family proteins in NK cells, showing that they are involved in regulation of CD122, Ly49 family and IFN-gamma expression during differentiation.
Tue Jan 01 00:00:00 EST 2008
Host transmission of Salmonella enterica serovar Typhimurium is controlled by virulence factors and indigenous intestinal microbiota.
Infection and immunity
Lawley TD,Bouley DM,Hoy YE,Gerke C,Relman DA,Monack DM
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Immunofluorescence
Tue Jan 01 00:00:00 EST 2008
Basophils are essential initiators of a novel type of chronic allergic inflammation.
Blood
Obata K,Mukai K,Tsujimura Y,Ishiwata K,Kawano Y,Minegishi Y,Watanabe N,Karasuyama H
11-5931 was used in Flow cytometry/Cell sorting to study a possible role for basophils in allergic disorders and immunity to pathogens.
Wed Aug 01 00:00:00 EDT 2007
Granulocyte colony-stimulating factor enhances bone tumor growth in mice in an osteoclast-dependent manner.
Blood
Hirbe AC,Uluçkan O,Morgan EA,Eagleton MC,Prior JL,Piwnica-Worms D,Trinkaus K,Apicelli A,Weilbaecher K
11-5931 was used in Flow cytometry/Cell sorting to investigate whether increased osteoclast activation enhances tumour growth in bone.
Sun Apr 15 00:00:00 EDT 2007
Listeria monocytogenes promotes tumor growth via tumor cell toll-like receptor 2 signaling.
Cancer research
Huang B,Zhao J,Shen S,Li H,He KL,Shen GX,Mayer L,Unkeless J,Li D,Yuan Y,Zhang GM,Xiong H,Feng ZH
Tue May 01 00:00:00 EDT 2007
Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1.
Journal of leukocyte biology
Sasmono RT,Ehrnsperger A,Cronau SL,Ravasi T,Kandane R,Hickey MJ,Cook AD,Himes SR,Hamilton JA,Hume DA
Sun Jul 01 00:00:00 EDT 2007
Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1.
Journal of leukocyte biology
Sasmono RT,Ehrnsperger A,Cronau SL,Ravasi T,Kandane R,Hickey MJ,Cook AD,Himes SR,Hamilton JA,Hume DA
Sun Jul 01 00:00:00 EDT 2007
Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1.
Journal of leukocyte biology
Sasmono RT,Ehrnsperger A,Cronau SL,Ravasi T,Kandane R,Hickey MJ,Cook AD,Himes SR,Hamilton JA,Hume DA
Sun Jul 01 00:00:00 EDT 2007
The mouse mammary carcinoma 4T1: characterization of the cellular landscape of primary tumours and metastatic tumour foci.
International journal of experimental pathology
DuPré SA,Redelman D,Hunter KW
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 11-5931-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2007
ADAM17 deficiency by mature neutrophils has differential effects on L-selectin shedding.
Blood
Li Y,Brazzell J,Herrera A,Walcheck B
11-5931 was used in Flow cytometry/Cell sorting to investigate the role of Adam17 in L-selectin shedding by mature neutrophils, showing that deficiency by mature neutrophils has differential effects on L-selectin shedding.
Sun Oct 01 00:00:00 EDT 2006
Hemorrhagic shock-activated neutrophils augment TLR4 signaling-induced TLR2 upregulation in alveolar macrophages: role in hemorrhage-primed lung inflammation.
American journal of physiology. Lung cellular and molecular physiology
Fan J,Li Y,Vodovotz Y,Billiar TR,Wilson MA
Sat Apr 01 00:00:00 EST 2006
Neutrophil signaling pathways activated by bacterial DNA stimulation.
Journal of immunology (Baltimore, Md. : 1950)
Alvarez ME,Fuxman Bass JI,Geffner JR,Fernández Calotti PX,Costas M,Coso OA,Gamberale R,Vermeulen ME,Salamone G,Martinez D,Tanos T,Trevani AS
11-5931-82 was used in flow cytometry to determine that bacterial DNA stimulated CD11b up-regulation in TLR9(-/-) but not in MyD88(-/-) mouse neutrophils, supporting that bacterial DNA induces neutrophil activation through a TLR9-independent and MyD88-dependent pathway.
Fri Sep 15 00:00:00 EDT 2006
Basophils play a critical role in the development of IgE-mediated chronic allergic inflammation independently of T cells and mast cells.
Immunity
Mukai K,Matsuoka K,Taya C,Suzuki H,Yokozeki H,Nishioka K,Hirokawa K,Etori M,Yamashita M,Kubota T,Minegishi Y,Yonekawa H,Karasuyama H
11-5931 was used in Flow cytometry/Cell sorting to reveal a novel basophil-induced mechanism of development of chronic allergic inflammation.
Mon Aug 01 00:00:00 EDT 2005
Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling.
Genes & development
Taghon TN,David ES,Zúñiga-Pflücker JC,Rothenberg EV
11-5931 was used in Flow cytometry/Cell sorting to study how Notch/Delta signaling is not sufficient for T-lineage specification and commitment, but can be permissive for the maintenance and proliferation of uncommitted progenitors.
Fri Apr 15 00:00:00 EDT 2005
Mice lacking the type I interferon receptor are resistant to Listeria monocytogenes.
The Journal of experimental medicine
Auerbuch V,Brockstedt DG,Meyer-Morse N,O'Riordan M,Portnoy DA
11-5931 was used in Flow cytometry/Cell sorting to investigate the role of type I interferon receptors in viral defense using Listeria monocytogenes infection of mice as a model.
Mon Aug 16 00:00:00 EDT 2004
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-RB6-8C5-RE-AV-20170920122035.jpg?time=20220826?time=20220826 "Ly-6G/Ly-6C Antibody (11-5931-82)")
