Product References
Calcaratarin D, a labdane diterpenoid, attenuates mouse asthma via modulating alveolar macrophage function.
British journal of pharmacology
Liao W,Foo HYC,Tran TNQ,Chai CLL,Wong WSF
45-5931-80 was used in Flow cytometry/Cell sorting to demonstrate for the first time that CalD is a novel anti-inflammatory natural compound for allergic asthma that modulates AM function.
Sat Apr 01 00:00:00 EDT 2023
Macrophage Reprogramming via the Modulation of Unfolded Protein Response with siRNA-Loaded Magnetic Nanoparticles in a TAM-like Experimental Model.
Pharmaceutics
D'Urso A,Oltolina F,Borsotti C,Prat M,Colangelo D,Follenzi A
45-5931-80 was used in Flow cytometry/Cell sorting to provide a novel strategy for the development of new tumor immunotherapies in vivo.
Mon Jun 12 00:00:00 EDT 2023
Stem cell architecture drives myelodysplastic syndrome progression and predicts response to venetoclax-based therapy.
Nature medicine
Ganan-Gomez I,Yang H,Ma F,Montalban-Bravo G,Thongon N,Marchica V,Richard-Carpentier G,Chien K,Manyam G,Wang F,Alfonso A,Chen S,Class C,Kanagal-Shamanna R,Ingram JP,Ogoti Y,Rose A,Loghavi S,Lockyer P,Cambo B,Muftuoglu M,Schneider S,Adema V,McLellan M,Garza J,Marchesini M,Giuliani N,Pellegrini M,Wang J,Walker J,Li Z,Takahashi K,Leverson JD,Bueso-Ramos C,Andreeff M,Clise-Dwyer K,Garcia-Manero G,Colla S
45-5931-80 was used in Flow Cytometry to study the biological mechanisms that drive hypomethylating agent therapy failure at the stem-cell level to uncover vulnerabilities in the disease and halt its evolution.
Tue Mar 01 00:00:00 EST 2022
Topoisomerase 1 inhibition modulates pyroptosis to improve recovery after spinal cord injury.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jiang W,He F,Ding G,Wu J
45-5931-80 was used in Flow cytometry/Cell sorting to indicate that inhibition of Top1 with CPT can inhibit pyroptosis, control neuroinflammation, and improve functional recovery after SCI.
Wed Jun 01 00:00:00 EDT 2022
Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis.
Cell host & microbe
Pandey SP,Bender MJ,McPherson AC,Phelps CM,Sanchez LM,Rana M,Hedden L,Sangani KA,Chen L,Shapira JH,Siller M,Goel C,Verdú EF,Jabri B,Chang A,Chandran UR,Mullett SJ,Wendell SG,Singhi AD,Tilstra JS,Pierre JF,Arteel GE,Hinterleitner R,Meisel M
45-5931-80 was used in Flow cytometry/Cell sorting to demonstrate that I3A is required for L. reuteri-induced Tc1 cell differentiation in vitro and AIH-like pathology in vivo, both of which are restrained by Tet2 within CD8 T cells.
Wed Jul 13 00:00:00 EDT 2022
Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation.
Immunity
Medina CB,Chiu YH,Stremska ME,Lucas CD,Poon I,Tung KS,Elliott MR,Desai B,Lorenz UM,Bayliss DA,Ravichandran KS
45-5931-80 was used in Flow cytometry/Cell sorting to uncover an immunoregulatory role for the nucleotide release channel, Panx1, in T cell crosstalk during airway disease.
Tue Aug 10 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
SZB120 Exhibits Immunomodulatory Effects by Targeting eIF2α to Suppress Th17 Cell Differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Chen L,Bai J,Peng D,Gao Y,Cai X,Zhang J,Tang S,Niu L,Sun Y,Lou F,Zhou H,Yin Q,Wang Z,Sun L,Du X,Xu Z,Wang H,Li Q,Wang H
45-5931-80 was used in Flow Cytometry to characterise the target and mechanism of an acetylated beta-boswellic acid derivative termed SZB120, and evaluate the anti-inflammatory activities in vitro and in vivo.
Mon Mar 01 00:00:00 EST 2021
BRD4-mediated repression of p53 is a target for combination therapy in AML.
Nature communications
Latif AL,Newcombe A,Li S,Gilroy K,Robertson NA,Lei X,Stewart HJS,Cole J,Terradas MT,Rishi L,McGarry L,McKeeve C,Reid C,Clark W,Campos J,Kirschner K,Davis A,Lopez J,Sakamaki JI,Morton JP,Ryan KM,Tait SWG,Abraham SA,Holyoake T,Higgins B,Huang X,Blyth K,Copland M,Chevassut TJT,Keeshan K,Adams PD
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Mon Jan 11 00:00:00 EST 2021
Design, Synthesis and Biological Evaluation of Arylpyridin-2-yl Guanidine Derivatives and Cyclic Mimetics as Novel MSK1 Inhibitors. An Application in an Asthma Model.
Molecules (Basel, Switzerland)
Bollenbach M,Nemska S,Wagner P,Camelin G,Daubeuf F,Obrecht A,Villa P,Rognan D,Bihel F,Bourguignon JJ,Schmitt M,Frossard N
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Wed Jan 13 00:00:00 EST 2021
IFNγ-Producing γ/δ T Cells Accumulate in the Fetal Brain Following Intrauterine Inflammation.
Frontiers in immunology
Lewis EL,Tulina N,Anton L,Brown AG,Porrett PM,Elovitz MA
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Wed Jan 05 00:00:00 EST 2022
Lung mesenchymal stromal cells influenced by Th2 cytokines mobilize neutrophils and facilitate metastasis by producing complement C3.
Nature communications
Zheng Z,Li YN,Jia S,Zhu M,Cao L,Tao M,Jiang J,Zhan S,Chen Y,Gao PJ,Hu W,Wang Y,Shao C,Shi Y
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Wed Oct 27 00:00:00 EDT 2021
Retinoic Acid Inhibits Tumor-Associated Mesenchymal Stromal Cell Transformation in Melanoma.
Frontiers in cell and developmental biology
Lou Q,Zhao M,Xu Q,Xie S,Liang Y,Chen J,Yuan L,Wang L,Jiang L,Mou L,Lin D,Zhao M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Sat Apr 24 00:00:00 EDT 2021
Comprehensive mutagenesis identifies the peptide repertoire of a p53 T-cell receptor mimic antibody that displays no toxicity in mice transgenic for human HLA-A*0201.
PloS one
Trenevska I,Anderson AP,Bentley C,Hassanali T,Wiblin S,Maguire S,Pezzella F,Banham AH,Li D
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Wed Sep 29 00:00:00 EDT 2021
Abraxane-induced bone marrow CD11b+ myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with 64Cu-labeled anti-CD11b and prevented by anti-CSF-1.
Theranostics
Cao Q,Huang Q,Wang YA,Li C
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Fri Jul 23 00:00:00 EDT 2021
Abraxane-induced bone marrow CD11b+ myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with 64Cu-labeled anti-CD11b and prevented by anti-CSF-1.
Theranostics
Cao Q,Huang Q,Wang YA,Li C
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Fri Jul 23 00:00:00 EDT 2021
Single-cell analyses unravel cell type-specific responses to a vitamin D analog in prostatic precancerous lesions.
Science advances
Abu El Maaty MA,Grelet E,Keime C,Rerra AI,Gantzer J,Emprou C,Terzic J,Lutzing R,Bornert JM,Laverny G,Metzger D
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Thu Jul 01 00:00:00 EDT 2021
Construction, characterization, and immunization of nanoparticles that display a diverse array of influenza HA trimers.
PloS one
Cohen AA,Yang Z,Gnanapragasam PNP,Ou S,Dam KA,Wang H,Bjorkman PJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Fri Oct 15 00:00:00 EDT 2021
Intravesical High Dose BCG Tokyo and Low Dose BCG Tokyo with GMCSF+IFN α Induce Systemic Immunity in a Murine Orthotopic Bladder Cancer Model.
Biomedicines
Tham SM,Rahmat JN,Chiong E,Wu Q,Esuvaranathan K,Mahendran R
45-5931-80 was used in Flow cytometry/Cell sorting to evaluate a short therapy schedule for bladder cancer using BCG Tokyo. BCG Tokyo was evaluated in vitro using bone marrow derived dendritic cells, neutrophils, RAW macrophages and the murine bladder cancer cell line, MB49PSA, and compared to other BCG strains.
Thu Nov 25 00:00:00 EST 2021
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist.
eLife
Glassman CR,Su L,Majri-Morrison SS,Winkelmann H,Mo F,Li P,Pérez-Cruz M,Ho PP,Koliesnik I,Nagy N,Hnizdilova T,Picton LK,Kovar M,Bollyky P,Steinman L,Meyer E,Piehler J,Leonard WJ,Garcia KC
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Tue May 18 00:00:00 EDT 2021
Febrile Temperature Critically Controls the Differentiation and Pathogenicity of T Helper 17 Cells.
Immunity
Wang X,Ni L,Wan S,Zhao X,Ding X,Dejean A,Dong C
45-5931 was used in Flow cytometry/Cell sorting to show that febrile temperature selectively regulated Th17 cell differentiation in vitro in enhancing interleukin-17 (IL-17), IL-17F, and IL-22 expression.
Tue Feb 18 00:00:00 EST 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
In Situ Therapeutic Cancer Vaccination with an Oncolytic Virus Expressing Membrane-Tethered IL-2.
Molecular therapy oncolytics
Liu W,Dai E,Liu Z,Ma C,Guo ZS,Bartlett DL
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Fri Jun 26 00:00:00 EDT 2020
Deficiency of immunoglobulin E protects mice from experimental abdominal aortic aneurysms.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Li J,Deng Z,Zhang X,Liu F,Yang C,Shi GP
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
Flagellin-Stimulated Production of Interferon-β Promotes Anti-Flagellin IgG2c and IgA Responses.
Molecules and cells
Kang W,Park A,Huh JW,You G,Jung DJ,Song M,Lee HK,Kim YM
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Tue Mar 31 00:00:00 EDT 2020
Effects of Hypertonic Saline and Hydroxyethyl Starch on Myeloid-Derived Suppressor Cells in Hemorrhagic Shock Mice under Secondary Bacterial Attack.
BioMed research international
Jiang JK,Hong LJ,Lu YQ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
Effects of Hypertonic Saline and Hydroxyethyl Starch on Myeloid-Derived Suppressor Cells in Hemorrhagic Shock Mice under Secondary Bacterial Attack.
BioMed research international
Jiang JK,Hong LJ,Lu YQ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
Long Non-Coding RNA Hotairm1 Promotes S100A9 Support of MDSC Expansion during Sepsis.
Journal of clinical & cellular immunology
Alkhateeb T,Bah I,Kumbhare A,Youssef D,Yao ZQ,McCall CE,Gazzar ME
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Sat Aug 13 00:00:00 EDT 2022
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection.
Cell reports
Dokoshi T,Zhang LJ,Li F,Nakatsuji T,Butcher A,Yoshida H,Shimoda M,Okada Y,Gallo RL
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Tue Jan 07 00:00:00 EST 2020
Protocol for Flow Cytometric Detection of Immune Cell Infiltration in the Epidermis and Dermis of a Psoriasis Mouse Model.
STAR protocols
Lou F,Sun Y,Wang H
45-5931-80 was used in Flow Cytometry to establish a mouse model of psoriasis and flow cytometric detection of immune cells in the inflamed epidermis and dermis.
Fri Dec 18 00:00:00 EST 2020
Protocol for Flow Cytometric Detection of Immune Cell Infiltration in the Epidermis and Dermis of a Psoriasis Mouse Model.
STAR protocols
Lou F,Sun Y,Wang H
45-5931-80 was used in Flow Cytometry to establish a mouse model of psoriasis and flow cytometric detection of immune cells in the inflamed epidermis and dermis.
Fri Dec 18 00:00:00 EST 2020
Loss of testosterone impairs anti-tumor neutrophil function.
Nature communications
Markman JL,Porritt RA,Wakita D,Lane ME,Martinon D,Noval Rivas M,Luu M,Posadas EM,Crother TR,Arditi M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Tue Mar 31 00:00:00 EDT 2020
Bacterial and Fungal Toll-Like Receptor Activation Elicits Type I IFN Responses in Mast Cells.
Frontiers in immunology
Kornstädt L,Pierre S,Weigert A,Ebersberger S,Schäufele TJ,Kolbinger A,Schmid T,Cohnen J,Thomas D,Ferreirós N,Brüne B,Ebersberger I,Scholich K
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Mon Jun 21 00:00:00 EDT 2021
Sensing and signaling of immunogenic extracellular RNAs restrain group 2 innate lymphoid cell-driven acute lung inflammation and airway hyperresponsiveness.
PloS one
She L,Alanazi HH,Yan L,Brooks EG,Dube PH,Xiang Y,Zhang F,Sun Y,Liu Y,Zhang X,Li XD
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Thu Sep 24 00:00:00 EDT 2020
Neutrophils contribute to spontaneous resolution of liver inflammation and fibrosis via microRNA-223.
The Journal of clinical investigation
Calvente CJ,Tameda M,Johnson CD,Del Pilar H,Lin YC,Adronikou N,De Mollerat Du Jeu X,Llorente C,Boyer J,Feldstein AE
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Thu Jul 11 00:00:00 EDT 2019
Gasdermin D in peripheral myeloid cells drives neuroinflammation in experimental autoimmune encephalomyelitis.
The Journal of experimental medicine
Li S,Wu Y,Yang D,Wu C,Ma C,Liu X,Moynagh PN,Wang B,Hu G,Yang S
45-5931-80 was used in Flow Cytometry to study how GSDMD deficiency in peripheral myeloid cells impaired the infiltration of immune cells into the CNS, leading to the suppression of neuroinflammation and demyelination.
Mon Nov 04 00:00:00 EST 2019
Neutrophil extracellular traps induced by VP1 contribute to pulmonary edema during EV71 infection.
Cell death discovery
Wang N,Yang X,Sun J,Sun Z,Ma Q,Wang Z,Chen Z,Wang Z,Hu F,Wang H,Zhou L,Zhang M,Xu J
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Wed Sep 30 00:00:00 EDT 2020
Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.
Nature
Meisel M,Hinterleitner R,Pacis A,Chen L,Earley ZM,Mayassi T,Pierre JF,Ernest JD,Galipeau HJ,Thuille N,Bouziat R,Buscarlet M,Ringus DL,Wang Y,Li Y,Dinh V,Kim SM,McDonald BD,Zurenski MA,Musch MW,Furtado GC,Lira SA,Baier G,Chang EB,Eren AM,Weber CR,Busque L,Godley LA,Verdú EF,Barreiro LB,Jabri B
45-5931 was used in Flow cytometry/Cell sorting to study the role played by bacterial translocation and increased interleukin-6 production in the development of pre-leukaemic myeloproliferation.
Tue May 01 00:00:00 EDT 2018
E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.
Immunity
Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Tue Feb 20 00:00:00 EST 2018
Investigation of tumor-tumor interactions in a double human cervical carcinoma xenograft model in nude mice.
Oncotarget
Mertens B,Cristina de Araujo Nogueira T,Topalis D,Stranska R,Snoeck R,Andrei G
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Tue Apr 24 00:00:00 EDT 2018
Antiviral effects of ferric ammonium citrate.
Cell discovery
Wang H,Li Z,Niu J,Xu Y,Ma L,Lu A,Wang X,Qian Z,Huang Z,Jin X,Leng Q,Wang J,Zhong J,Sun B,Meng G
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2020
Induction of neutrophil apoptosis by a Bcl-2 inhibitor reduces particulate matter-induced lung inflammation.
Aging
Geng X,Wang X,Luo M,Xing M,Wu Y,Li W,Chen Z,Shen H,Ying S
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Tue Jun 26 00:00:00 EDT 2018
Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice.
mSphere
Quach D,Collins F,Parameswaran N,McCabe L,Britton RA
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
CD24-p53 axis suppresses diethylnitrosamine-induced hepatocellular carcinogenesis by sustaining intrahepatic macrophages.
Cell discovery
Li D,Hu M,Liu Y,Ye P,Du P,Li CS,Cheng L,Liu P,Jiang J,Su L,Wang S,Zheng P,Liu Y
45-5931-80 was used in Flow cytometry/Cell sorting to show that targeted mutation of Cd24 dramatically increased HCC burden while reducing intrahepatic macrophages and DEN-induced hepatocyte apoptosis.
Thu Oct 01 00:00:00 EDT 2020
Peripheral myeloid cells contribute to brain injury in male neonatal mice.
Journal of neuroinflammation
Smith PLP,Mottahedin A,Svedin P,Mohn CJ,Hagberg H,Ek J,Mallard C
45-5931 was used in Flow cytometry/Cell sorting to investigate the role of peripheral myeloid cells in neonatal hypoxic-ischaemic brain injury.
Tue Oct 30 00:00:00 EDT 2018
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
45-5931 was used in Flow cytometry/Cell sorting to study paediatric acute myeloid leukaemia biology, and provide murine models that offer the potential for developing paediatric specific therapeutic strategies.
Tue Dec 11 00:00:00 EST 2018
SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia.
Nature medicine
Schneider C,Oellerich T,Baldauf HM,Schwarz SM,Thomas D,Flick R,Bohnenberger H,Kaderali L,Stegmann L,Cremer A,Martin M,Lohmeyer J,Michaelis M,Hornung V,Schliemann C,Berdel WE,Hartmann W,Wardelmann E,Comoglio F,Hansmann ML,Yakunin AF,Geisslinger G,Ströbel P,Ferreirós N,Serve H,Keppler OT,Cinatl J
45593180 was used in flow cytometry to demonstrate that SAMHD1 reduces nucleoside analog cytarabine cytotoxicity in acute myeloid leukemia cells
Wed Feb 01 00:00:00 EST 2017
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
Cell
Keren-Shaul H,Spinrad A,Weiner A,Matcovitch-Natan O,Dvir-Szternfeld R,Ulland TK,David E,Baruch K,Lara-Astaiso D,Toth B,Itzkovitz S,Colonna M,Schwartz M,Amit I
45-5931-80 was used in Flow Cytometry to map all immune populations in wild-type and Alzheimer's disease-transgenic mouse brains.
Thu Jun 15 00:00:00 EDT 2017
Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia.
Cancer cell
Mohr S,Doebele C,Comoglio F,Berg T,Beck J,Bohnenberger H,Alexe G,Corso J,Ströbel P,Wachter A,Beissbarth T,Schnütgen F,Cremer A,Haetscher N,Göllner S,Rouhi A,Palmqvist L,Rieger MA,Schroeder T,Bönig H,Müller-Tidow C,Kuchenbauer F,Schütz E,Green AR,Urlaub H,Stegmaier K,Humphries RK,Serve H,Oellerich T
45-5931 was used in Immunocytochemistry to study the effects of combined Hoxa9/Meis1 over-expression on intracellular signalling, and whether cells transformed by Hoxa9 and Meis1 become addicted to targetable signalling processes.
Mon Apr 10 00:00:00 EDT 2017
Brd4 modulates the innate immune response through Mnk2-eIF4E pathway-dependent translational control of IκBα.
Proceedings of the National Academy of Sciences of the United States of America
Bao Y,Wu X,Chen J,Hu X,Zeng F,Cheng J,Jin H,Lin X,Chen LF
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Tue May 16 00:00:00 EDT 2017
Primary Heligmosomoides polygyrus bakeri infection induces myeloid-derived suppressor cells that suppress CD4+ Th2 responses and promote chronic infection.
Mucosal immunology
Valanparambil RM,Tam M,Jardim A,Geary TG,Stevenson MM
45-5931 was used in Flow cytometry/Cell sorting to study the exact identity and role of the F4/80-CD11b+Gr+ cells accumulating around encysting larvae in intestinal tissue during primary Heligmosomoides polygyrus bakeri infection in mice.
Sun Jan 01 00:00:00 EST 2017
Distribution and differentiation of myeloid-derived suppressor cells after fluid resuscitation in mice with hemorrhagic shock.
Journal of Zhejiang University. Science. B
Jiang JK,Fang W,Hong LJ,Lu YQ
45-5931 was used in Flow cytometry/Cell sorting to investigate the distribution and differentiation of myeloid-derived suppressor cells in hemorrhagic shock mice, which are resuscitated with various fluids.
Tue Jul 11 00:00:00 EDT 2017
Autophagy in Dendritic Cells and B Cells Is Critical for the Inflammatory State of TLR7-Mediated Autoimmunity.
Journal of immunology (Baltimore, Md. : 1950)
Weindel CG,Richey LJ,Mehta AJ,Shah M,Huber BT
45-5931 was used in Flow cytometry/Cell sorting to identify that autophagy in B cells and dendritic cells are key to TLR7-mediated autoimmune disorders.
Wed Feb 01 00:00:00 EST 2017
Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-κB signaling and NLRP3 activation.
International journal of molecular medicine
Zhang B,Wang B,Cao S,Wang Y,Wu D
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.
RNA biology
Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Thu May 04 00:00:00 EDT 2017
Role of Prolactin in Promotion of Immune Cell Migration into the Mammary Gland.
Journal of mammary gland biology and neoplasia
Dill R,Walker AM
45-5931 was used in Flow cytometry/Cell sorting to investigate the role of prolactin in immune cell recruitment.
Wed Mar 01 00:00:00 EST 2017
MiR-125a Is a critical modulator for neutrophil development.
PLoS genetics
Qin Y,Wu L,Ouyang Y,Zhou P,Zhou H,Wang Y,Ma J,Zhang J,Chen Y,Qian J,Tang Y,Shen N
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells.
Oncotarget
Guo XL,Chu L,Ke F,Mu LL,Li Z,Cai JJ,Li HF,Hong DL
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Tue Dec 12 00:00:00 EST 2017
BOT-4-one attenuates NLRP3 inflammasome activation: NLRP3 alkylation leading to the regulation of its ATPase activity and ubiquitination.
Scientific reports
Shim DW,Shin WY,Yu SH,Kim BH,Ye SK,Koppula S,Won HS,Kang TB,Lee KH
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Wed Nov 08 00:00:00 EST 2017
Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis.
Nature communications
Trabanelli S,Chevalier MF,Martinez-Usatorre A,Gomez-Cadena A,Salomé B,Lecciso M,Salvestrini V,Verdeil G,Racle J,Papayannidis C,Morita H,Pizzitola I,Grandclément C,Bohner P,Bruni E,Girotra M,Pallavi R,Falvo P,Leibundgut EO,Baerlocher GM,Carlo-Stella C,Taurino D,Santoro A,Spinelli O,Rambaldi A,Giarin E,Basso G,Tresoldi C,Ciceri F,Gfeller D,Akdis CA,Mazzarella L,Minucci S,Pelicci PG,Marcenaro E,McKenzie ANJ,Vanhecke D,Coukos G,Mavilio D,Curti A,Derré L,Jandus C
45-5931 was used in Flow cytometry/Cell sorting to elucidate the function of group 2 innate lymphoid cells in human cancer.
Tue Sep 19 00:00:00 EDT 2017
Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates.
Nature biotechnology
Vegas AJ,Veiseh O,Doloff JC,Ma M,Tam HH,Bratlie K,Li J,Bader AR,Langan E,Olejnik K,Fenton P,Kang JW,Hollister-Locke J,Bochenek MA,Chiu A,Siebert S,Tang K,Jhunjhunwala S,Aresta-Dasilva S,Dholakia N,Thakrar R,Vietti T,Chen M,Cohen J,Siniakowicz K,Qi M,McGarrigle J,Graham AC,Lyle S,Harlan DM,Greiner DL,Oberholzer J,Weir GC,Langer R,Anderson DG
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Thu Aug 25 00:00:00 EDT 2016
Macrophage autophagy limits acute toxic liver injury in mice through down regulation of interleukin-1β.
Journal of hepatology
Ilyas G,Zhao E,Liu K,Lin Y,Tesfa L,Tanaka KE,Czaja MJ
45-5931 was used in Flow cytometry/Cell sorting to show that macrophage autophagy functions to limit acute toxin-induced liver injury and death by inhibiting the generation of inflammasome-dependent IL-1β.
Fri Jan 01 00:00:00 EST 2016
SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages.
Autophagy
Kim MJ,Bae SH,Ryu JC,Kwon Y,Oh JH,Kwon J,Moon JS,Kim K,Miyawaki A,Lee MG,Shin J,Kim YS,Kim CH,Ryter SW,Choi AM,Rhee SG,Ryu JH,Yoon JH
45-5931 was used in Flow cytometry/Cell sorting to define a unique regulatory mechanism of mitophagy activation for immunological homeostasis that protects the host from sepsis.
Tue Aug 02 00:00:00 EDT 2016
Multiple myeloma exosomes establish a favourable bone marrow microenvironment with enhanced angiogenesis and immunosuppression.
The Journal of pathology
Wang J,De Veirman K,Faict S,Frassanito MA,Ribatti D,Vacca A,Menu E
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth.
Stem cells translational medicine
Zheng H,Zou W,Shen J,Xu L,Wang S,Fu YX,Fan W
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.
Immunology
Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Sat Oct 01 00:00:00 EDT 2016
The miR-17∼92 cluster contributes to MLL leukemia through the repression of MEIS1 competitor PKNOX1.
Leukemia research
Mian YA,Zeleznik-Le NJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Fri Jul 01 00:00:00 EDT 2016
Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.
Stem cell reports
Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Tue Aug 09 00:00:00 EDT 2016
Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury.
Cell death & disease
Di Siena S,Gimmelli R,Nori SL,Barbagallo F,Campolo F,Dolci S,Rossi P,Venneri MA,Giannetta E,Gianfrilli D,Feigenbaum L,Lenzi A,Naro F,Cianflone E,Mancuso T,Torella D,Isidori AM,Pellegrini M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Thu Jul 28 00:00:00 EDT 2016
Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice.
BMC genomics
Leist SR,Pilzner C,van den Brand JM,Dengler L,Geffers R,Kuiken T,Balling R,Kollmus H,Schughart K
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Sat Feb 27 00:00:00 EST 2016
miR-150 regulates obesity-associated insulin resistance by controlling B cell functions.
Scientific reports
Ying W,Tseng A,Chang RC,Wang H,Lin YL,Kanameni S,Brehm T,Morin A,Jones B,Splawn T,Criscitiello M,Golding MC,Bazer FW,Safe S,Zhou B
45-5931 was used in Flow cytometry/Cell sorting to demonstrate a role for miR-150 in regulating B cell functions in adipose tissue.
Mon Feb 01 00:00:00 EST 2016
The REGγ-proteasome forms a regulatory circuit with IκBɛ and NFκB in experimental colitis.
Nature communications
Xu J,Zhou L,Ji L,Chen F,Fortmann K,Zhang K,Liu Q,Li K,Wang W,Wang H,Xie W,Wang Q,Liu J,Zheng B,Zhang P,Huang S,Shi T,Zhang B,Dang Y,Chen J,O'Malley BW,Moses RE,Wang P,Li L,Xiao J,Hoffmann A,Li X
45-5931 was used in Flow cytometry/Cell sorting to explore a role of REGγ in the regulation of NFκB and the effect of this on the development of bowel inflammation and associated tumour formation.
Mon Feb 22 00:00:00 EST 2016
Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.
Blood
Matthews GM,Mehdipour P,Cluse LA,Falkenberg KJ,Wang E,Roth M,Santoro F,Vidacs E,Stanley K,House CM,Rusche JR,Vakoc CR,Zuber J,Minucci S,Johnstone RW
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Thu Nov 19 00:00:00 EST 2015
MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation.
The Journal of clinical investigation
Ying W,Tseng A,Chang RC,Morin A,Brehm T,Triff K,Nair V,Zhuang G,Song H,Kanameni S,Wang H,Golding MC,Bazer FW,Chapkin RS,Safe S,Zhou B
45-5931 was used in Flow cytometry/Cell sorting to investigate the regulatory network of polarised activation of adipose tissue macrophages.
Mon Nov 02 00:00:00 EST 2015
Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAF(V600E) melanoma.
Science translational medicine
Hu-Lieskovan S,Mok S,Homet Moreno B,Tsoi J,Robert L,Goedert L,Pinheiro EM,Koya RC,Graeber TG,Comin-Anduix B,Ribas A
45-5931 was used in Flow cytometry/Cell sorting to investigate the use of BRAF and MEK inhibitors with immunotherapy in patients with BRAF(V600E) melanoma.
Wed Mar 18 00:00:00 EDT 2015
Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions.
Journal of immunology (Baltimore, Md. : 1950)
Thiele M,Kerschbaumer RJ,Tam FW,Völkel D,Douillard P,Schinagl A,Kühnel H,Smith J,McDaid JP,Bhangal G,Yu MC,Pusey CD,Cook HT,Kovarik J,Magelky E,Bhan A,Rieger M,Mudde GC,Ehrlich H,Jilma B,Tilg H,Moschen A,Terhorst C,Scheiflinger F
45-5931 was used in Flow cytometry/Cell sorting to demonstrate that oxMIF represents the disease-related isoform of MIF and is therefore a new diagnostic marker for inflammation.
Tue Sep 01 00:00:00 EDT 2015
A far-red fluorescent probe for flow cytometry and image-based functional studies of xenobiotic sequestering macrophages.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Keswani RK,Yoon GS,Sud S,Stringer KA,Rosania GR
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Local delivery of VEGF and SDF enhances endothelial progenitor cell recruitment and resultant recovery from ischemia.
Tissue engineering. Part A
Anderson EM,Kwee BJ,Lewin SA,Raimondo T,Mehta M,Mooney DJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway.
Molecular medicine reports
Huang L,Kong Y,Wang J,Sun J,Shi Q,Qiu YH
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
The bone marrow microenvironment enhances multiple myeloma progression by exosome-mediated activation of myeloid-derived suppressor cells.
Oncotarget
Wang J,De Veirman K,De Beule N,Maes K,De Bruyne E,Van Valckenborgh E,Vanderkerken K,Menu E
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Tue Dec 22 00:00:00 EST 2015
Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.
PloS one
Szulzewsky F,Pelz A,Feng X,Synowitz M,Markovic D,Langmann T,Holtman IR,Wang X,Eggen BJ,Boddeke HW,Hambardzumyan D,Wolf SA,Kettenmann H
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2016
Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts.
Stem cell reports
Neri T,Muggeo S,Paulis M,Caldana ME,Crisafulli L,Strina D,Focarelli ML,Faggioli F,Recordati C,Scaramuzza S,Scanziani E,Mantero S,Buracchi C,Sobacchi C,Lombardo A,Naldini L,Vezzoni P,Villa A,Ficara F
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Tue Oct 13 00:00:00 EDT 2015
Sunitinib depletes myeloid-derived suppressor cells and synergizes with a cancer vaccine to enhance antigen-specific immune responses and tumor eradication.
Oncoimmunology
Draghiciu O,Nijman HW,Hoogeboom BN,Meijerhof T,Daemen T
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2015
Interferon-γ from Brain Leukocytes Enhances Meningitis by Type 4 Streptococcus pneumoniae.
Frontiers in microbiology
Pettini E,Fiorino F,Cuppone AM,Iannelli F,Medaglini D,Pozzi G
45-5931 was used in Flow cytometry/Cell sorting to elucidate the role of IFN-γ in the neuroinflammatory response following type 4 Streptococcus pneumoniae-induced meningitis in mice.
Wed Dec 09 00:00:00 EST 2015
Host adaptation of a bacterial toxin from the human pathogen Salmonella Typhi.
Cell
Deng L,Song J,Gao X,Wang J,Yu H,Chen X,Varki N,Naito-Matsui Y,Galán JE,Varki A
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Thu Dec 04 00:00:00 EST 2014
Biliary repair and carcinogenesis are mediated by IL-33-dependent cholangiocyte proliferation.
The Journal of clinical investigation
Li J,Razumilava N,Gores GJ,Walters S,Mizuochi T,Mourya R,Bessho K,Wang YH,Glaser SS,Shivakumar P,Bezerra JA
45-5931 was used in Flow cytometry/Cell sorting to demonstrate the role of the Th2-promoting cytokine, IL-33, in cholangiocyte proliferation.
Tue Jul 01 00:00:00 EDT 2014
Myeloid cell-specific ATP-binding cassette transporter A1 deletion has minimal impact on atherogenesis in atherogenic diet-fed low-density lipoprotein receptor knockout mice.
Arteriosclerosis, thrombosis, and vascular biology
Bi X,Zhu X,Gao C,Shewale S,Cao Q,Liu M,Boudyguina E,Gebre AK,Wilson MD,Brown AL,Parks JS
45-5931 was used in Flow cytometry/Cell sorting to assess the atherosclerotic impact of myeloid cell ATP-binding cassette transporter A1.
Mon Sep 01 00:00:00 EDT 2014
Macrophages contribute to the cyclic activation of adult hair follicle stem cells.
PLoS biology
Castellana D,Paus R,Perez-Moreno M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Mon Dec 01 00:00:00 EST 2014
Parasite fate and involvement of infected cells in the induction of CD4+ and CD8+ T cell responses to Toxoplasma gondii.
PLoS pathogens
Dupont CD,Christian DA,Selleck EM,Pepper M,Leney-Greene M,Harms Pritchard G,Koshy AA,Wagage S,Reuter MA,Sibley LD,Betts MR,Hunter CA
45-5931 was used in Flow cytometry/Cell sorting to identify a critical role for actively infected host cells in initiating T. gondii-specific CD4+ and CD8+ T cell responses.
Tue Apr 01 00:00:00 EDT 2014
The plexin C1 receptor promotes acute inflammation.
European journal of immunology
König K,Marth L,Roissant J,Granja T,Jennewein C,Devanathan V,Schneider M,Köhler D,Zarbock A,Rosenberger P
45-5931 was used in Flow cytometry/Cell sorting to study the role of plexin C1 during the acute inflammatory response.
Mon Sep 01 00:00:00 EDT 2014
Functional effects of TGF-β1 on mesenchymal stem cell mobilization in cockroach allergen-induced asthma.
Journal of immunology (Baltimore, Md. : 1950)
Gao P,Zhou Y,Xian L,Li C,Xu T,Plunkett B,Huang SK,Wan M,Cao X
45-5931 was used in Flow cytometry/Cell sorting to investigate the role of TGF-β1 in mesenchymal stem cell migration in allergic asthma.
Thu May 15 00:00:00 EDT 2014
Anti-tumor innate immunity activated by intermittent metronomic cyclophosphamide treatment of 9L brain tumor xenografts is preserved by anti-angiogenic drugs that spare VEGF receptor 2.
Molecular cancer
Doloff JC,Chen CS,Waxman DJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Thu Jun 26 00:00:00 EDT 2014
Activation of NLRP3 inflammasome by crystalline structures via cell surface contact.
Scientific reports
Hari A,Zhang Y,Tu Z,Detampel P,Stenner M,Ganguly A,Shi Y
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Tue Dec 02 00:00:00 EST 2014
Purinergic signaling on leukocytes infiltrating the LPS-injured lung.
PloS one
Friebe D,Yang T,Schmidt T,Borg N,Steckel B,Ding Z,Schrader J
45-5931 was used in Flow cytometry/Cell sorting to investigate the role of extracellular nucleotides/nucleosides in acute lung injury, showing purinergic signaling on leukocytes infiltrating the injured lung.
Thu Jan 15 00:00:00 EST 2015
Ecto-5'-nucleotidase on immune cells protects from adverse cardiac remodeling.
Circulation research
Bönner F,Borg N,Jacoby C,Temme S,Ding Z,Flögel U,Schrader J
45-5931 was used in Flow cytometry/Cell sorting to examine the role of CD73 in cardiac repair and remodelling in mice after reperfused myocardial infarction.
Fri Jul 19 00:00:00 EDT 2013
Distinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells.
Development (Cambridge, England)
Tober J,Yzaguirre AD,Piwarzyk E,Speck NA
45-5931 was used in Flow cytometry/Cell sorting to study how the requirements for Runx1 in erythroid/myeloid progenitors and hematopoietic stem cell formation are temporally distinct.
Sun Sep 01 00:00:00 EDT 2013
Differential effects of aging and sex on stroke induced inflammation across the lifespan.
Experimental neurology
Manwani B,Liu F,Scranton V,Hammond MD,Sansing LH,McCullough LD
45-5931 was used in Flow cytometry/Cell sorting to evaluate the relative contribution of several key factors determining stroke outcome.
Fri Nov 01 00:00:00 EDT 2013
CD11b+GR1+ myeloid cells secrete NGF and promote trigeminal ganglion neurite growth: implications for corneal nerve regeneration.
Investigative ophthalmology & visual science
Sarkar J,Chaudhary S,Jassim SH,Ozturk O,Chamon W,Ganesh B,Tibrewal S,Gandhi S,Byun YS,Hallak J,Mahmud DL,Mahmud N,Rondelli D,Jain S
45-5931 was used in Flow cytometry/Cell sorting to study trigeminal ganglion neurites using mice with fluorescent bone marrow cells to show increased growth when CD11b+GR1+ myeloid cells secrete NGF.
Tue Sep 03 00:00:00 EDT 2013
The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects.
The Journal of biological chemistry
Zamanian-Daryoush M,Lindner D,Tallant TC,Wang Z,Buffa J,Klipfell E,Parker Y,Hatala D,Parsons-Wingerter P,Rayman P,Yusufishaq MSS,Fisher EA,Smith JD,Finke J,DiDonato JA,Hazen SL
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Fri Jul 19 00:00:00 EDT 2013
Myeloid cell-specific ABCA1 deletion protects mice from bacterial infection.
Circulation research
Zhu X,Westcott MM,Bi X,Liu M,Gowdy KM,Seo J,Cao Q,Gebre AK,Fessler MB,Hiltbold EM,Parks JS
45-5931 was used in Flow cytometry/Cell sorting to investigate whether macrophage expression of ATP-binding cassette transporter A1 impacts host defence function in mice.
Fri Nov 09 00:00:00 EST 2012
STAT1-independent control of a neurotropic measles virus challenge in primary neurons and infected mice.
Journal of immunology (Baltimore, Md. : 1950)
O'Donnell LA,Conway S,Rose RW,Nicolas E,Slifker M,Balachandran S,Rall GF
45-5931 was used in Flow cytometry/Cell sorting to determine whether STAT1 is required for IFN-γ-mediated protection from infection in neurons, showing that absence of STAT1 in mice did not restrict the ability of IFN-γ to control viral infection, through a pathway independent of the usual pathway.
Wed Feb 15 00:00:00 EST 2012
Differential gene expression in mice infected with distinct Toxoplasma strains.
Infection and immunity
Hill RD,Gouffon JS,Saxton AM,Su C
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2012
A model of GAG/MIP-2/CXCR2 interfaces and its functional effects.
Biochemistry
Rajasekaran D,Keeler C,Syed MA,Jones MC,Harrison JK,Wu D,Bhandari V,Hodsdon ME,Lolis EJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Tue Jul 17 00:00:00 EDT 2012
Virotherapy of canine tumors with oncolytic vaccinia virus GLV-1h109 expressing an anti-VEGF single-chain antibody.
PloS one
Patil SS,Gentschev I,Adelfinger M,Donat U,Hess M,Weibel S,Nolte I,Frentzen A,Szalay AA
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Thu Mar 28 00:00:00 EDT 2013
In vivo inhibition of c-MYC in myeloid cells impairs tumor-associated macrophage maturation and pro-tumoral activities.
PloS one
Pello OM,Chèvre R,Laoui D,De Juan A,Lolo F,Andrés-Manzano MJ,Serrano M,Van Ginderachter JA,Andrés V
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Mon Feb 25 00:00:00 EST 2013
Novel murine dendritic cell lines: a powerful auxiliary tool for dendritic cell research.
Frontiers in immunology
Fuertes Marraco SA,Grosjean F,Duval A,Rosa M,Lavanchy C,Ashok D,Haller S,Otten LA,Steiner QG,Descombes P,Luber CA,Meissner F,Mann M,Szeles L,Reith W,Acha-Orbea H
45-5931 was used in Flow cytometry/Cell sorting to report the generation of new murine DC lines, named MutuDC, originating from cultures of splenic CD8α conventional DC (cDC) tumours.
Tue Nov 20 00:00:00 EST 2012
Resident cardiac immune cells and expression of the ectonucleotidase enzymes CD39 and CD73 after ischemic injury.
PloS one
Bönner F,Borg N,Burghoff S,Schrader J
45-5931 was used in Flow cytometry/Cell sorting to explore the abundance of CD73 and CD39 on immune cells under control conditions and in response to inflammation.
Thu Aug 30 00:00:00 EDT 2012
Rara haploinsufficiency modestly influences the phenotype of acute promyelocytic leukemia in mice.
Blood
Welch JS,Klco JM,Varghese N,Nagarajan R,Ley TJ
45-5931 was used in Flow cytometry/Cell sorting to test the prediction that RARA (retinoic acid receptor alpha) haploinsufficiency would contribute to acute promyelocytic leukemia (APL) pathogenesis.
Thu Feb 24 00:00:00 EST 2011
Genetic deletion of chemokine receptor Ccr6 decreases atherogenesis in ApoE-deficient mice.
Circulation research
Wan W,Lim JK,Lionakis MS,Rivollier A,McDermott DH,Kelsall BL,Farber JM,Murphy PM
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Fri Aug 05 00:00:00 EDT 2011
PML-RARA can increase hematopoietic self-renewal without causing a myeloproliferative disease in mice.
The Journal of clinical investigation
Welch JS,Yuan W,Ley TJ
45-5931 was used in Flow cytometry/Cell sorting to study a platform for more accurately dissecting the early events in acute promyelocytic leukemia pathogenesis.
Fri Apr 01 00:00:00 EDT 2011
Th2 signals induce epithelial injury in mice and are compatible with the biliary atresia phenotype.
The Journal of clinical investigation
Li J,Bessho K,Shivakumar P,Mourya R,Mohanty SK,Dos Santos JL,Miura IK,Porta G,Bezerra JA
45-5931 was used in Flow cytometry/Cell sorting to assess whether Th1-independent mechanisms can activate effector cells to induce biliary atresia.
Tue Nov 01 00:00:00 EDT 2011
A mouse model of airway disease: oncostatin M-induced pulmonary eosinophilia, goblet cell hyperplasia, and airway hyperresponsiveness are STAT6 dependent, and interstitial pulmonary fibrosis is STAT6 independent.
Journal of immunology (Baltimore, Md. : 1950)
Fritz DK,Kerr C,Fattouh R,Llop-Guevara A,Khan WI,Jordana M,Richards CD
45-5931 was used in Flow cytometry/Cell sorting to suggest that eosinophil or neutrophil accumulation in mouse lungs is not required for oncostatin M-induced lung parenchymal collagen deposition.
Sat Jan 15 00:00:00 EST 2011
Membrane-associated CD93 regulates leukocyte migration and C1q-hemolytic activity during murine peritonitis.
Journal of immunology (Baltimore, Md. : 1950)
Greenlee-Wacker MC,Briseño C,Galvan M,Moriel G,Velázquez P,Bohlson SS
45-5931 was used in Flow cytometry/Cell sorting to demonstrate and understand a heightened susceptibility to thioglycollate-induced peritonitis in CD93(-/-) mice.
Thu Sep 15 00:00:00 EDT 2011
Local mesenchymal stem/progenitor cells are a preferential target for initiation of adult soft tissue sarcomas associated with p53 and Rb deficiency.
The American journal of pathology
Choi J,Curtis SJ,Roy DM,Flesken-Nikitin A,Nikitin AY
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2010
The presence of professional phagocytes dictates the number of host cells targeted for Yop translocation during infection.
Cellular microbiology
Durand EA,Maldonado-Arocho FJ,Castillo C,Walsh RL,Mecsas J
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Sun Aug 01 00:00:00 EDT 2010
CCR7 deficiency leads to leukocyte activation and increased clearance in response to pulmonary Pseudomonas aeruginosa infection.
Infection and immunity
Eppert BL,Motz GT,Wortham BW,Flury JL,Borchers MT
45-5931 was used in Flow cytometry/Cell sorting to investigate the roles of CCR7 in the host defense against pulmonary infection, showing that CCR7 deficiency leads to leukocyte activation and increased infection clearance.
Sat May 01 00:00:00 EDT 2010
CBFbeta is critical for AML1-ETO and TEL-AML1 activity.
Blood
Roudaia L,Cheney MD,Manuylova E,Chen W,Morrow M,Park S,Lee CT,Kaur P,Williams O,Bushweller JH,Speck NA
45-5931 was used in Flow cytometry/Cell sorting to validate the AML1-ETO and TEL-AML1 chimeric protein Runt domain/CBFbeta interaction as a therapeutic target in core binding factor leukemias.
Thu Mar 26 00:00:00 EDT 2009
TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.
Cellular immunology
Drage MG,Pecora ND,Hise AG,Febbraio M,Silverstein RL,Golenbock DT,Boom WH,Harding CV
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Fri Jun 12 00:00:00 EDT 2009
Listeria monocytogenes promotes tumor growth via tumor cell toll-like receptor 2 signaling.
Cancer research
Huang B,Zhao J,Shen S,Li H,He KL,Shen GX,Mayer L,Unkeless J,Li D,Yuan Y,Zhang GM,Xiong H,Feng ZH
Tue May 01 00:00:00 EDT 2007
The mouse mammary carcinoma 4T1: characterization of the cellular landscape of primary tumours and metastatic tumour foci.
International journal of experimental pathology
DuPré SA,Redelman D,Hunter KW
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 45-5931-80) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2007
Hemorrhagic shock-activated neutrophils augment TLR4 signaling-induced TLR2 upregulation in alveolar macrophages: role in hemorrhage-primed lung inflammation.
American journal of physiology. Lung cellular and molecular physiology
Fan J,Li Y,Vodovotz Y,Billiar TR,Wilson MA
Sat Apr 01 00:00:00 EST 2006
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-RB6-8C5-RE-AV-20170920122035.jpg?time=20220826?time=20220826 "Ly-6G/Ly-6C Antibody (45-5931-80)")
