Invitrogen

Ly-6G/Ly-6C Monoclonal Antibody (RB6-8C5), eFluor™ 506, eBioscience™

Ly-6G/Ly-6C Antibody in Flow Cytometry (Flow)

FIGURE: 1 / 99

Ly-6G/Ly-6C Antibody (69-5931-82) in Flow

C57BL/6 mouse bone marrow cells were stained with CD11b Monoclonal Antibody, PE (Product # 12-0112-85) and 0.06 µg of Rat IgG2b kappa Isotype Control, eFluor 506 (Product # 69-4031-82) (left) or 0.06 µg of Ly-6G/Ly-6C Monoclonal Antibody, eFluor 506 (right). Cells in the myeloid gate were used for analysis.

Ly-6G/Ly-6C Antibody in Immunocytochemistry (ICC/IF)

Ly-6G/Ly-6C Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Ly-6G/Ly-6C Antibody in Immunohistochemistry (Frozen) (IHC (F))

Ly-6G/Ly-6C Antibody in Immunohistochemistry (IHC)

Product Image Gallery

Product Details

69-5931-82

Applications

Tested Dilution

Publications

Western Blot (WB)

View 1 publication 1 publication

Immunohistochemistry (IHC)

View 16 publications 16 publications

Immunohistochemistry (Paraffin) (IHC (P))

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Flow Cytometry (Flow)

0.125 µg/test

View 80 publications 80 publications

In Situ Hybridization (ISH) (ISH)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Mouse

Published species

Mouse

Host/Isotype

Rat / IgG2b, kappa

Recommended Isotype Control

Rat IgG2b kappa Isotype Control (eB149/10H5), eFluor™ 506, eBioscience™

Class

Monoclonal

Type

Antibody

Clone

RB6-8C5

Conjugate

eFluor™ 506 eFluor™ 506 eFluor™ 506

Excitation/Emission Max

419/508 nm View spectra

Form

Liquid

Concentration

0.2 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2

Contains

0.09% sodium azide

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2866456

Product Specific Information

Description: The RB6-8C5 monoclonal antibody reacts with mouse Ly-6G, a 21-25 kDa protein also known as the myeloid differentiation antigen Gr-1. A GPI-linked protein, Gr-1 is expressed by the myeloid lineage in a developmentally regulated manner in the bone marrow. While monocytes only express Gr-1 transiently during their bone marrow development, the expression of Gr-1 on bone marrow granulocytes as well as on peripheral neutrophils is a good marker for these populations.

eBioscience testing indicates that in the bone marrow and lysed whole blood, the antibody clone RB6-8C5 also stains cells that express the highest levels of Ly6c (as defined by staining with antibody clone HK1.4). It is recommended that 1A8-Ly6G (Product # 9668) be used when looking at Ly-6G specific targets.

Applications Reported: This RB6-8C5 antibody has been reported for use in flow cytometric analysis.

Applications Tested: This RB6-8C5 antibody has been tested by flow cytometric analysis of mouse bone marrow cells. This may be used at less than or equal to 0.125 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

eFluor 506 can be excited with the violet laser line (405 nm) and emits at 506 nm. We recommend using a 510/20 band pass filter, or equivalent. Please make sure that your instrument is capable of detecting this fluorochrome.

Excitation: 405 nm; Emission: 506 nm; Laser: Violet Laser.

Target Information

Granulocytes are a category of white blood cells characterised by the presence of granules in their cytoplasm. They are also called polymorphonuclear leukocytes (PMN or PML) because of the varying shapes of the nucleus, which is usually lobed into three segments. In common parlance, the term polymorphonuclear leukocyte often refers specifically to neutrophil granulocytes, the most abundant of the granulocytes. Granulocytes or PMN are released from the bone marrow by the regulatory complement proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

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PloS one

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Hsu SF,Lee YB,Lee YC,Chung AL,Apaya MK,Shyur LF,Cheng CF,Ho FM,Meng TC

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Tue May 01 00:00:00 EDT 2018

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Oncotarget

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Analysis of leukocyte transepithelial migration using an in vivo murine colonic loop model.

JCI insight

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Thu Oct 18 00:00:00 EDT 2018

Antiviral effects of ferric ammonium citrate.

Cell discovery

Wang H,Li Z,Niu J,Xu Y,Ma L,Lu A,Wang X,Qian Z,Huang Z,Jin X,Leng Q,Wang J,Zhong J,Sun B,Meng G

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Tue Sep 29 00:00:00 EDT 2020

Induction of neutrophil apoptosis by a Bcl-2 inhibitor reduces particulate matter-induced lung inflammation.

Aging

Geng X,Wang X,Luo M,Xing M,Wu Y,Li W,Chen Z,Shen H,Ying S

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Tue Jun 26 00:00:00 EDT 2018

Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice.

mSphere

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Wed Nov 20 00:00:00 EST 2019

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Nature materials

Doloff JC,Veiseh O,Vegas AJ,Tam HH,Farah S,Ma M,Li J,Bader A,Chiu A,Sadraei A,Aresta-Dasilva S,Griffin M,Jhunjhunwala S,Webber M,Siebert S,Tang K,Chen M,Langan E,Dholokia N,Thakrar R,Qi M,Oberholzer J,Greiner DL,Langer R,Anderson DG

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Thu Jun 01 00:00:00 EDT 2017

Brd4 modulates the innate immune response through Mnk2-eIF4E pathway-dependent translational control of IκBα.

Proceedings of the National Academy of Sciences of the United States of America

Bao Y,Wu X,Chen J,Hu X,Zeng F,Cheng J,Jin H,Lin X,Chen LF

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Tue May 16 00:00:00 EDT 2017

Cardiac inflammation in genetic dilated cardiomyopathy caused by MYBPC3 mutation.

Journal of molecular and cellular cardiology

Lynch TL,Ismahil MA,Jegga AG,Zilliox MJ,Troidl C,Prabhu SD,Sadayappan S

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Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-κB signaling and NLRP3 activation.

International journal of molecular medicine

Zhang B,Wang B,Cao S,Wang Y,Wu D

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Mon May 01 00:00:00 EDT 2017

ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.

RNA biology

Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M

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Thu May 04 00:00:00 EDT 2017

Coinjection of IL2 DNA enhances E7-specific antitumor immunity elicited by intravaginal therapeutic HPV DNA vaccination with electroporation.

Gene therapy

Sun Y,Peng S,Yang A,Farmer E,Wu TC,Hung CF

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MiR-125a Is a critical modulator for neutrophil development.

PLoS genetics

Qin Y,Wu L,Ouyang Y,Zhou P,Zhou H,Wang Y,Ma J,Zhang J,Chen Y,Qian J,Tang Y,Shen N

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Sun Oct 01 00:00:00 EDT 2017

Gastric TFF1 Expression from Acute to Chronic Helicobacter Infection.

Frontiers in cellular and infection microbiology

Esposito R,Morello S,Vllahu M,Eletto D,Porta A,Tosco A

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Mon Jul 09 00:00:00 EDT 2018

Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells.

Oncotarget

Guo XL,Chu L,Ke F,Mu LL,Li Z,Cai JJ,Li HF,Hong DL

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Tue Dec 12 00:00:00 EST 2017

BOT-4-one attenuates NLRP3 inflammasome activation: NLRP3 alkylation leading to the regulation of its ATPase activity and ubiquitination.

Scientific reports

Shim DW,Shin WY,Yu SH,Kim BH,Ye SK,Koppula S,Won HS,Kang TB,Lee KH

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Wed Nov 08 00:00:00 EST 2017

Tumor-Derived Exosomes Induce the Formation of Neutrophil Extracellular Traps: Implications For The Establishment of Cancer-Associated Thrombosis.

Scientific reports

Leal AC,Mizurini DM,Gomes T,Rochael NC,Saraiva EM,Dias MS,Werneck CC,Sielski MS,Vicente CP,Monteiro RQ

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Immunohistochemistry

Tue Jul 25 00:00:00 EDT 2017

One Year Follow-Up Risk Assessment in SKH-1 Mice and Wounds Treated with an Argon Plasma Jet.

International journal of molecular sciences

Schmidt A,Woedtke TV,Stenzel J,Lindner T,Polei S,Vollmar B,Bekeschus S

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Immunohistochemistry

Wed Apr 19 00:00:00 EDT 2017

Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates.

Nature biotechnology

Vegas AJ,Veiseh O,Doloff JC,Ma M,Tam HH,Bratlie K,Li J,Bader AR,Langan E,Olejnik K,Fenton P,Kang JW,Hollister-Locke J,Bochenek MA,Chiu A,Siebert S,Tang K,Jhunjhunwala S,Aresta-Dasilva S,Dholakia N,Thakrar R,Vietti T,Chen M,Cohen J,Siniakowicz K,Qi M,McGarrigle J,Graham AC,Lyle S,Harlan DM,Greiner DL,Oberholzer J,Weir GC,Langer R,Anderson DG

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Tue Mar 01 00:00:00 EST 2016

The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.

Cell

Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Thu Aug 25 00:00:00 EDT 2016

Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth.

Stem cells translational medicine

Zheng H,Zou W,Shen J,Xu L,Wang S,Fu YX,Fan W

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Thu Sep 01 00:00:00 EDT 2016

Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.

Immunology

Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Sat Oct 01 00:00:00 EDT 2016

Effects of ketanserin on experimental colitis in mice and macrophage function.

International journal of molecular medicine

Xiao J,Shao L,Shen J,Jiang W,Feng Y,Zheng P,Liu F

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Tue Mar 01 00:00:00 EST 2016

The miR-17∼92 cluster contributes to MLL leukemia through the repression of MEIS1 competitor PKNOX1.

Leukemia research

Mian YA,Zeleznik-Le NJ

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Fri Jul 01 00:00:00 EDT 2016

Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.

Stem cell reports

Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Tue Aug 09 00:00:00 EDT 2016

Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury.

Cell death & disease

Di Siena S,Gimmelli R,Nori SL,Barbagallo F,Campolo F,Dolci S,Rossi P,Venneri MA,Giannetta E,Gianfrilli D,Feigenbaum L,Lenzi A,Naro F,Cianflone E,Mancuso T,Torella D,Isidori AM,Pellegrini M

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Thu Jul 28 00:00:00 EDT 2016

Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice.

BMC genomics

Leist SR,Pilzner C,van den Brand JM,Dengler L,Geffers R,Kuiken T,Balling R,Kollmus H,Schughart K

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Sat Feb 27 00:00:00 EST 2016

C/EBP homologous protein (CHOP) deficiency ameliorates renal fibrosis in unilateral ureteral obstructive kidney disease.

Oncotarget

Liu SH,Wu CT,Huang KH,Wang CC,Guan SS,Chen LP,Chiang CK

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Immunohistochemistry (Paraffin)

Tue Apr 19 00:00:00 EDT 2016

Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.

Blood

Matthews GM,Mehdipour P,Cluse LA,Falkenberg KJ,Wang E,Roth M,Santoro F,Vidacs E,Stanley K,House CM,Rusche JR,Vakoc CR,Zuber J,Minucci S,Johnstone RW

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Thu Nov 19 00:00:00 EST 2015

A far-red fluorescent probe for flow cytometry and image-based functional studies of xenobiotic sequestering macrophages.

Cytometry. Part A : the journal of the International Society for Analytical Cytology

Keswani RK,Yoon GS,Sud S,Stringer KA,Rosania GR

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Tue Sep 01 00:00:00 EDT 2015

Local delivery of VEGF and SDF enhances endothelial progenitor cell recruitment and resultant recovery from ischemia.

Tissue engineering. Part A

Anderson EM,Kwee BJ,Lewin SA,Raimondo T,Mehta M,Mooney DJ

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Wed Apr 01 00:00:00 EDT 2015

Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway.

Molecular medicine reports

Huang L,Kong Y,Wang J,Sun J,Shi Q,Qiu YH

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Tue Sep 01 00:00:00 EDT 2015

The bone marrow microenvironment enhances multiple myeloma progression by exosome-mediated activation of myeloid-derived suppressor cells.

Oncotarget

Wang J,De Veirman K,De Beule N,Maes K,De Bruyne E,Van Valckenborgh E,Vanderkerken K,Menu E

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Tue Dec 22 00:00:00 EST 2015

The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia.

Nature communications

Koh HS,Chang CY,Jeon SB,Yoon HJ,Ahn YH,Kim HS,Kim IH,Jeon SH,Johnson RS,Park EJ

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Immunohistochemistry

Fri Mar 20 00:00:00 EDT 2015

Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.

PloS one

Szulzewsky F,Pelz A,Feng X,Synowitz M,Markovic D,Langmann T,Holtman IR,Wang X,Eggen BJ,Boddeke HW,Hambardzumyan D,Wolf SA,Kettenmann H

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Tue Jan 12 00:00:00 EST 2016

Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts.

Stem cell reports

Neri T,Muggeo S,Paulis M,Caldana ME,Crisafulli L,Strina D,Focarelli ML,Faggioli F,Recordati C,Scaramuzza S,Scanziani E,Mantero S,Buracchi C,Sobacchi C,Lombardo A,Naldini L,Vezzoni P,Villa A,Ficara F

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Tue Oct 13 00:00:00 EDT 2015

Sunitinib depletes myeloid-derived suppressor cells and synergizes with a cancer vaccine to enhance antigen-specific immune responses and tumor eradication.

Oncoimmunology

Draghiciu O,Nijman HW,Hoogeboom BN,Meijerhof T,Daemen T

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Sun Mar 01 00:00:00 EST 2015

Host adaptation of a bacterial toxin from the human pathogen Salmonella Typhi.

Cell

Deng L,Song J,Gao X,Wang J,Yu H,Chen X,Varki N,Naito-Matsui Y,Galán JE,Varki A

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Thu Dec 04 00:00:00 EST 2014

Macrophages contribute to the cyclic activation of adult hair follicle stem cells.

PLoS biology

Castellana D,Paus R,Perez-Moreno M

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Mon Dec 01 00:00:00 EST 2014

Anti-tumor innate immunity activated by intermittent metronomic cyclophosphamide treatment of 9L brain tumor xenografts is preserved by anti-angiogenic drugs that spare VEGF receptor 2.

Molecular cancer

Doloff JC,Chen CS,Waxman DJ

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Thu Jun 26 00:00:00 EDT 2014

Activation of NLRP3 inflammasome by crystalline structures via cell surface contact.

Scientific reports

Hari A,Zhang Y,Tu Z,Detampel P,Stenner M,Ganguly A,Shi Y

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Tue Dec 02 00:00:00 EST 2014

Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros.

Nature immunology

Schjerven H,McLaughlin J,Arenzana TL,Frietze S,Cheng D,Wadsworth SE,Lawson GW,Bensinger SJ,Farnham PJ,Witte ON,Smale ST

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Tue Oct 01 00:00:00 EDT 2013

Arrayed lentiviral barcoding for quantification analysis of hematopoietic dynamics.

Stem cells (Dayton, Ohio)

Grosselin J,Sii-Felice K,Payen E,Chretien S,Tronik-Le Roux D,Leboulch P

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Tue Oct 01 00:00:00 EDT 2013

The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects.

The Journal of biological chemistry

Zamanian-Daryoush M,Lindner D,Tallant TC,Wang Z,Buffa J,Klipfell E,Parker Y,Hatala D,Parsons-Wingerter P,Rayman P,Yusufishaq MSS,Fisher EA,Smith JD,Finke J,DiDonato JA,Hazen SL

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Fri Jul 19 00:00:00 EDT 2013

R-spondin 2 signalling mediates susceptibility to fatal infectious diarrhoea.

Nature communications

Papapietro O,Teatero S,Thanabalasuriar A,Yuki KE,Diez E,Zhu L,Kang E,Dhillon S,Muise AM,Durocher Y,Marcinkiewicz MM,Malo D,Gruenheid S

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in In Situ Hybridization (ISH)

Mon Dec 30 00:00:00 EST 2013

Differential gene expression in mice infected with distinct Toxoplasma strains.

Infection and immunity

Hill RD,Gouffon JS,Saxton AM,Su C

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Thu Mar 01 00:00:00 EST 2012

Preclinical evaluation of oncolytic vaccinia virus for therapy of canine soft tissue sarcoma.

PloS one

Gentschev I,Adelfinger M,Josupeit R,Rudolph S,Ehrig K,Donat U,Weibel S,Chen NG,Yu YA,Zhang Q,Heisig M,Thamm D,Stritzker J,Macneill A,Szalay AA

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Immunohistochemistry

Thu Sep 20 00:00:00 EDT 2012

Virotherapy of canine tumors with oncolytic vaccinia virus GLV-1h109 expressing an anti-VEGF single-chain antibody.

PloS one

Patil SS,Gentschev I,Adelfinger M,Donat U,Hess M,Weibel S,Nolte I,Frentzen A,Szalay AA

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Immunohistochemistry

Thu Mar 28 00:00:00 EDT 2013

Virotherapy of canine tumors with oncolytic vaccinia virus GLV-1h109 expressing an anti-VEGF single-chain antibody.

PloS one

Patil SS,Gentschev I,Adelfinger M,Donat U,Hess M,Weibel S,Nolte I,Frentzen A,Szalay AA

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Immunohistochemistry

Thu Mar 28 00:00:00 EDT 2013

Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment.

Cell communication and signaling : CCS

Wiechert L,Németh J,Pusterla T,Bauer C,De Ponti A,Manthey S,Marhenke S,Vogel A,Klingmüller U,Hess J,Angel P

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Sat Dec 15 00:00:00 EST 2012

Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment.

Cell communication and signaling : CCS

Wiechert L,Németh J,Pusterla T,Bauer C,De Ponti A,Manthey S,Marhenke S,Vogel A,Klingmüller U,Hess J,Angel P

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Sat Dec 15 00:00:00 EST 2012

In vivo inhibition of c-MYC in myeloid cells impairs tumor-associated macrophage maturation and pro-tumoral activities.

PloS one

Pello OM,Chèvre R,Laoui D,De Juan A,Lolo F,Andrés-Manzano MJ,Serrano M,Van Ginderachter JA,Andrés V

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Mon Feb 25 00:00:00 EST 2013

Genetic deletion of chemokine receptor Ccr6 decreases atherogenesis in ApoE-deficient mice.

Circulation research

Wan W,Lim JK,Lionakis MS,Rivollier A,McDermott DH,Kelsall BL,Farber JM,Murphy PM

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Fri Aug 05 00:00:00 EDT 2011

A tritherapy combination of a fusion protein vaccine with immune-modulating doses of sequential chemotherapies in an optimized regimen completely eradicates large tumors in mice.

International journal of cancer

Song X,Guo W,Cui J,Qian X,Yi L,Chang M,Cai Q,Zhao Q

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Tue Mar 01 00:00:00 EST 2011

MMP9 is protective against lethal inflammatory mass lesions in the mouse colon.

Disease models & mechanisms

Hald A,Rønø B,Melander MC,Ding M,Holck S,Lund LR

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Immunohistochemistry

Tue Mar 01 00:00:00 EST 2011

DNA alkylating therapy induces tumor regression through an HMGB1-mediated activation of innate immunity.

Journal of immunology (Baltimore, Md. : 1950)

Guerriero JL,Ditsworth D,Catanzaro JM,Sabino G,Furie MB,Kew RR,Crawford HC,Zong WX

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Tue Mar 15 00:00:00 EDT 2011

Brain dendritic cells in ischemic stroke: time course, activation state, and origin.

Brain, behavior, and immunity

Felger JC,Abe T,Kaunzner UW,Gottfried-Blackmore A,Gal-Toth J,McEwen BS,Iadecola C,Bulloch K

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Thu Jul 01 00:00:00 EDT 2010

Local mesenchymal stem/progenitor cells are a preferential target for initiation of adult soft tissue sarcomas associated with p53 and Rb deficiency.

The American journal of pathology

Choi J,Curtis SJ,Roy DM,Flesken-Nikitin A,Nikitin AY

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Mon Nov 01 00:00:00 EDT 2010

The presence of professional phagocytes dictates the number of host cells targeted for Yop translocation during infection.

Cellular microbiology

Durand EA,Maldonado-Arocho FJ,Castillo C,Walsh RL,Mecsas J

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Sun Aug 01 00:00:00 EDT 2010

Combination of all-trans retinoic acid and a human papillomavirus therapeutic vaccine suppresses the number and function of immature myeloid cells and enhances antitumor immunity.

Cancer science

Song X,Ye D,Liu B,Cui J,Zhao X,Yi L,Liang J,Song J,Zhang Z,Zhao Q

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Sun Feb 01 00:00:00 EST 2009

Cellular expression and antimicrobial function of a phylogenetically conserved novel histone 1x-like protein on mouse cells: a potential new class of pattern recognition receptor.

Journal of leukocyte biology

Evans DL,Connor MA,Moss LD,Lackay S,Leary JH,Krunkosky T,Jaso-Friedmann L

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Wed Jul 01 00:00:00 EDT 2009

TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.

Cellular immunology

Drage MG,Pecora ND,Hise AG,Febbraio M,Silverstein RL,Golenbock DT,Boom WH,Harding CV

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Fri Jun 12 00:00:00 EDT 2009

The mouse mammary carcinoma 4T1: characterization of the cellular landscape of primary tumours and metastatic tumour foci.

International journal of experimental pathology

DuPré SA,Redelman D,Hunter KW

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Flow Cytometry

Mon Oct 01 00:00:00 EDT 2007

Neutralization of Gro alpha and macrophage inflammatory protein-2 attenuates renal ischemia/reperfusion injury.

The American journal of pathology

Miura M,Fu X,Zhang QW,Remick DG,Fairchild RL

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Immunohistochemistry

Sat Dec 01 00:00:00 EST 2001

Neutralization of Gro alpha and macrophage inflammatory protein-2 attenuates renal ischemia/reperfusion injury.

The American journal of pathology

Miura M,Fu X,Zhang QW,Remick DG,Fairchild RL

Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 69-5931-82) in Immunohistochemistry

Sat Dec 01 00:00:00 EST 2001

Bioinformatics

Protein Aliases: Granulocyte Marker; Ly-6C1; Ly-6C2; Ly-6G; Ly-6G.1; lymphocyte antigen 6 complex, locus C; lymphocyte antigen 6C precursor (Ly-6C); Lymphocyte antigen 6C1; Lymphocyte antigen 6C2; Lymphocyte antigen 6G; Lymphocyte antigen Ly-6C; lymphocyte differentiation antigen; PML; PMN

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Gene Aliases: AA682074; AA959465; Gr-1; Gr1; Ly-6C; Ly-6C.2; Ly-6C1; Ly-6C2; Ly-6G; Ly6c; Ly6c1; Ly6c2; Ly6g

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UniProt ID: (Mouse) P0CW02, (Mouse) P0CW03, (Mouse) P35461

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Entrez Gene ID: (Mouse) 17067, (Mouse) 100041546, (Mouse) 546644

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Ly-6G/Ly-6C Monoclonal Antibody (RB6-8C5), eFluor™ 506, eBioscience™

Ly-6G/Ly-6C Antibody (69-5931-82) in Flow

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69-5931-82

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