Product References
NLRP12-expressing dendritic cells mediate both dissemination of infection and adaptive immune responses in visceral leishmaniasis.
iScience
Valadares DG,Clay OS,Chen Y,Scorza BM,Cassel SL,Sutterwala FS,Wilson ME
17-5931-82 was used in Flow Cytometry to hypothesize that Nlrp12-expressing DCs are required for efficient dissemination and immune clearance of L. infantum from the site of initial infection.
Fri Mar 17 00:00:00 EDT 2023
RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells.
Nature communications
Herrejon Chavez F,Luo H,Cifani P,Pine A,Chu KL,Joshi S,Barin E,Schurer A,Chan M,Chang K,Han GYQ,Pierson AJ,Xiao M,Yang X,Kuehm LM,Hong Y,Nguyen DTT,Chiosis G,Kentsis A,Leslie C,Vu LP,Kharas MG
17-5931-82 was used in Flow cytometry/Cell sorting to reveal that the RNA-binding protein SYNCRIP is required for maintenance of blood homeostasis especially after regenerative stress due to defects in HSCs and progenitors.
Fri Apr 21 00:00:00 EDT 2023
Tet-mediated DNA demethylation regulates specification of hematopoietic stem and progenitor cells during mammalian embryogenesis.
Science advances
Ma L,Tang Q,Gao X,Lee J,Lei R,Suzuki M,Zheng D,Ito K,Frenette PS,Dawlaty MM
17-5931-82 was used in Flow Cytometry to investigate the postgastrulation functions of ten-eleven translocation (Tet) enzymes.
Fri Mar 04 00:00:00 EST 2022
Ferroptosis Inducer Improves the Efficacy of Oncolytic Virus-Mediated Cancer Immunotherapy.
Biomedicines
Liu W,Chen H,Zhu Z,Liu Z,Ma C,Lee YJ,Bartlett DL,Guo ZS
17-5931-82 was used in Flow cytometry/Cell sorting to demonstrate that erastin can exert cytotoxicity on cancer cells via ferroptosis, but has little effect on immune activity by itself.
Wed Jun 15 00:00:00 EDT 2022
Regulation of chromatin accessibility by the histone chaperone CAF-1 sustains lineage fidelity.
Nature communications
Franklin R,Guo Y,He S,Chen M,Ji F,Zhou X,Frankhouser D,Do BT,Chiem C,Jang M,Blanco MA,Vander Heiden MG,Rockne RC,Ninova M,Sykes DB,Hochedlinger K,Lu R,Sadreyev RI,Murn J,Volk A,Cheloufi S
17-5931-82 was used in Flow cytometry/Cell sorting to decipher key traits of chromatin accessibility that sustain lineage integrity and point to a powerful strategy for dissecting transcriptional circuits central to cell fate commitment.
Fri Apr 29 00:00:00 EDT 2022
Increased alveolar epithelial TRAF6 via autophagy-dependent TRIM37 degradation mediates particulate matter-induced lung metastasis.
Autophagy
Liu J,Li S,Fei X,Nan X,Shen Y,Xiu H,Cormier SA,Lu C,Guo C,Wang S,Cai Z,Wang P
17-5931-82 was used in Flow cytometry/Cell sorting to demonstrate the central role of PM-induced neutrophil recruitment in promoting lung cancer metastasis.
Sun May 01 00:00:00 EDT 2022
Virulence factors perforate the pathogen-containing vacuole to signal efferocytosis.
Cell host & microbe
Hiyoshi H,English BC,Diaz-Ochoa VE,Wangdi T,Zhang LF,Sakaguchi M,Haneda T,Tsolis RM,Bäumler AJ
17-5931-82 was used in Flow cytometry/Cell sorting to identify virulence factor-induced perforation of the PCV as a strategy of intracellular pathogens to generate a find-me signal for efferocytosis.
Wed Feb 09 00:00:00 EST 2022
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Exposure to Low to Moderate Doses of Ionizing Radiation Induces A Reduction of Pro-Inflammatory Ly6chigh Monocytes and a U-Curved Response of T Cells in APOE -/- Mice.
Dose-response : a publication of International Hormesis Society
Rey N,Ebrahimian T,Gloaguen C,Kereselidze D,Magneron V,Bontemps CA,Demarquay C,Olsson G,Haghdoost S,Lehoux S,Ebrahimian TG
17-5931-82 was used in Flow Cytometry to investigate the immunomodulatory response of different doses and dose-rates of irradiation in ApoE-/- mice.
Fri Jun 25 00:00:00 EDT 2021
BRD4-mediated repression of p53 is a target for combination therapy in AML.
Nature communications
Latif AL,Newcombe A,Li S,Gilroy K,Robertson NA,Lei X,Stewart HJS,Cole J,Terradas MT,Rishi L,McGarry L,McKeeve C,Reid C,Clark W,Campos J,Kirschner K,Davis A,Lopez J,Sakamaki JI,Morton JP,Ryan KM,Tait SWG,Abraham SA,Holyoake T,Higgins B,Huang X,Blyth K,Copland M,Chevassut TJT,Keeshan K,Adams PD
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Mon Jan 11 00:00:00 EST 2021
Design, Synthesis and Biological Evaluation of Arylpyridin-2-yl Guanidine Derivatives and Cyclic Mimetics as Novel MSK1 Inhibitors. An Application in an Asthma Model.
Molecules (Basel, Switzerland)
Bollenbach M,Nemska S,Wagner P,Camelin G,Daubeuf F,Obrecht A,Villa P,Rognan D,Bihel F,Bourguignon JJ,Schmitt M,Frossard N
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Wed Jan 13 00:00:00 EST 2021
IFNγ-Producing γ/δ T Cells Accumulate in the Fetal Brain Following Intrauterine Inflammation.
Frontiers in immunology
Lewis EL,Tulina N,Anton L,Brown AG,Porrett PM,Elovitz MA
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Wed Jan 05 00:00:00 EST 2022
Lung mesenchymal stromal cells influenced by Th2 cytokines mobilize neutrophils and facilitate metastasis by producing complement C3.
Nature communications
Zheng Z,Li YN,Jia S,Zhu M,Cao L,Tao M,Jiang J,Zhan S,Chen Y,Gao PJ,Hu W,Wang Y,Shao C,Shi Y
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Wed Oct 27 00:00:00 EDT 2021
Retinoic Acid Inhibits Tumor-Associated Mesenchymal Stromal Cell Transformation in Melanoma.
Frontiers in cell and developmental biology
Lou Q,Zhao M,Xu Q,Xie S,Liang Y,Chen J,Yuan L,Wang L,Jiang L,Mou L,Lin D,Zhao M
17-5931-82 was used in Flow Cytometry to investigate the mechanism by which IL-17, cooperating with IFNγ, transforms bone marrow mesenchymal stem/stromal cells into tumor-associated MSCs and how this facilitates tumor progression.
Sat Apr 24 00:00:00 EDT 2021
Retinoic Acid Inhibits Tumor-Associated Mesenchymal Stromal Cell Transformation in Melanoma.
Frontiers in cell and developmental biology
Lou Q,Zhao M,Xu Q,Xie S,Liang Y,Chen J,Yuan L,Wang L,Jiang L,Mou L,Lin D,Zhao M
17-5931-82 was used in Flow Cytometry to investigate the mechanism by which IL-17, cooperating with IFNγ, transforms bone marrow mesenchymal stem/stromal cells into tumor-associated MSCs and how this facilitates tumor progression.
Sat Apr 24 00:00:00 EDT 2021
Comprehensive mutagenesis identifies the peptide repertoire of a p53 T-cell receptor mimic antibody that displays no toxicity in mice transgenic for human HLA-A*0201.
PloS one
Trenevska I,Anderson AP,Bentley C,Hassanali T,Wiblin S,Maguire S,Pezzella F,Banham AH,Li D
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Wed Sep 29 00:00:00 EDT 2021
Abraxane-induced bone marrow CD11b+ myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with 64Cu-labeled anti-CD11b and prevented by anti-CSF-1.
Theranostics
Cao Q,Huang Q,Wang YA,Li C
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Fri Jul 23 00:00:00 EDT 2021
Single-cell analyses unravel cell type-specific responses to a vitamin D analog in prostatic precancerous lesions.
Science advances
Abu El Maaty MA,Grelet E,Keime C,Rerra AI,Gantzer J,Emprou C,Terzic J,Lutzing R,Bornert JM,Laverny G,Metzger D
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Thu Jul 01 00:00:00 EDT 2021
Construction, characterization, and immunization of nanoparticles that display a diverse array of influenza HA trimers.
PloS one
Cohen AA,Yang Z,Gnanapragasam PNP,Ou S,Dam KA,Wang H,Bjorkman PJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Fri Oct 15 00:00:00 EDT 2021
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist.
eLife
Glassman CR,Su L,Majri-Morrison SS,Winkelmann H,Mo F,Li P,Pérez-Cruz M,Ho PP,Koliesnik I,Nagy N,Hnizdilova T,Picton LK,Kovar M,Bollyky P,Steinman L,Meyer E,Piehler J,Leonard WJ,Garcia KC
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Tue May 18 00:00:00 EDT 2021
Annexin A1 drives macrophage skewing to accelerate muscle regeneration through AMPK activation.
The Journal of clinical investigation
McArthur S,Juban G,Gobbetti T,Desgeorges T,Theret M,Gondin J,Toller-Kawahisa JE,Reutelingsperger CP,Chazaud B,Perretti M,Mounier R
17-5931 was used in Flow cytometry/Cell sorting to explore the role of Annexin A1 in skeletal muscle injury regeneration.
Mon Mar 02 00:00:00 EST 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
Radiation causes tissue damage by dysregulating inflammasome-gasdermin D signaling in both host and transplanted cells.
PLoS biology
Xiao J,Wang C,Yao JC,Alippe Y,Yang T,Kress D,Sun K,Kostecki KL,Monahan JB,Veis DJ,Abu-Amer Y,Link DC,Mbalaviele G
17-5931 was used in Flow cytometry/Cell sorting to test the hypothesis that lethal radiation damages tissues, thereby unleashing signals that indiscriminately activate the inflammasome pathways in host and transplanted cells.
Sat Aug 01 00:00:00 EDT 2020
In Situ Therapeutic Cancer Vaccination with an Oncolytic Virus Expressing Membrane-Tethered IL-2.
Molecular therapy oncolytics
Liu W,Dai E,Liu Z,Ma C,Guo ZS,Bartlett DL
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Fri Jun 26 00:00:00 EDT 2020
In Situ Therapeutic Cancer Vaccination with an Oncolytic Virus Expressing Membrane-Tethered IL-2.
Molecular therapy oncolytics
Liu W,Dai E,Liu Z,Ma C,Guo ZS,Bartlett DL
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Fri Jun 26 00:00:00 EDT 2020
Deficiency of immunoglobulin E protects mice from experimental abdominal aortic aneurysms.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Li J,Deng Z,Zhang X,Liu F,Yang C,Shi GP
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
Mice carrying an analogous heterozygous dynamin 2 K562E mutation that causes neuropathy in humans develop predominant characteristics of a primary myopathy.
Human molecular genetics
Pereira JA,Gerber J,Ghidinelli M,Gerber D,Tortola L,Ommer A,Bachofner S,Santarella F,Tinelli E,Lin S,Rüegg MA,Kopf M,Toyka KV,Suter U
17-5931 was used in Flow cytometry/Cell sorting to describe the analysis of mice carrying the DNM2 K562E mutation which has been associated with dominant-intermediate CMT type B.
Thu May 28 00:00:00 EDT 2020
Flagellin-Stimulated Production of Interferon-β Promotes Anti-Flagellin IgG2c and IgA Responses.
Molecules and cells
Kang W,Park A,Huh JW,You G,Jung DJ,Song M,Lee HK,Kim YM
17-5931 was used in Flow cytometry/Cell sorting to shed a new light on the regulation of flagellin-mediated immune activation and may help find new strategies to promote the intestinal health and develop mucosal vaccines.
Tue Mar 31 00:00:00 EDT 2020
Flagellin-Stimulated Production of Interferon-β Promotes Anti-Flagellin IgG2c and IgA Responses.
Molecules and cells
Kang W,Park A,Huh JW,You G,Jung DJ,Song M,Lee HK,Kim YM
17-5931 was used in Flow cytometry/Cell sorting to shed a new light on the regulation of flagellin-mediated immune activation and may help find new strategies to promote the intestinal health and develop mucosal vaccines.
Tue Mar 31 00:00:00 EDT 2020
Effects of Hypertonic Saline and Hydroxyethyl Starch on Myeloid-Derived Suppressor Cells in Hemorrhagic Shock Mice under Secondary Bacterial Attack.
BioMed research international
Jiang JK,Hong LJ,Lu YQ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
Long Non-Coding RNA Hotairm1 Promotes S100A9 Support of MDSC Expansion during Sepsis.
Journal of clinical & cellular immunology
Alkhateeb T,Bah I,Kumbhare A,Youssef D,Yao ZQ,McCall CE,Gazzar ME
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Sat Aug 13 00:00:00 EDT 2022
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
17-5931 was used in Flow cytometry/Cell sorting to show that disruption of the Gdpd3 gene encoding a lysophospholipase D enzyme decreases the self-renewal capacity of murine chronic myelogenous leukaemia stem cells.
Thu Sep 17 00:00:00 EDT 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
17-5931 was used in Flow cytometry/Cell sorting to show that disruption of the Gdpd3 gene encoding a lysophospholipase D enzyme decreases the self-renewal capacity of murine chronic myelogenous leukaemia stem cells.
Thu Sep 17 00:00:00 EDT 2020
Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection.
Cell reports
Dokoshi T,Zhang LJ,Li F,Nakatsuji T,Butcher A,Yoshida H,Shimoda M,Okada Y,Gallo RL
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Tue Jan 07 00:00:00 EST 2020
Loss of testosterone impairs anti-tumor neutrophil function.
Nature communications
Markman JL,Porritt RA,Wakita D,Lane ME,Martinon D,Noval Rivas M,Luu M,Posadas EM,Crother TR,Arditi M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Tue Mar 31 00:00:00 EDT 2020
Bacterial and Fungal Toll-Like Receptor Activation Elicits Type I IFN Responses in Mast Cells.
Frontiers in immunology
Kornstädt L,Pierre S,Weigert A,Ebersberger S,Schäufele TJ,Kolbinger A,Schmid T,Cohnen J,Thomas D,Ferreirós N,Brüne B,Ebersberger I,Scholich K
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Mon Jun 21 00:00:00 EDT 2021
Sensing and signaling of immunogenic extracellular RNAs restrain group 2 innate lymphoid cell-driven acute lung inflammation and airway hyperresponsiveness.
PloS one
She L,Alanazi HH,Yan L,Brooks EG,Dube PH,Xiang Y,Zhang F,Sun Y,Liu Y,Zhang X,Li XD
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Thu Sep 24 00:00:00 EDT 2020
Protocol for Flow Cytometric Detection of Immune Cell Infiltration in the Epidermis and Dermis of a Psoriasis Mouse Model.
STAR protocols
Lou F,Sun Y,Wang H
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Fri Dec 18 00:00:00 EST 2020
Loss of FGFR3 Delays Acute Myeloid Leukemogenesis by Programming Weakly Pathogenic CD117-Positive Leukemia Stem-Like Cells.
Frontiers in pharmacology
Guo C,Ran Q,Sun C,Zhou T,Yang X,Zhang J,Pang S,Xiao Y
17-5931-82 was used in Flow Cytometry to find that FGFR3 had a novel regulatory mechanism for the stemness of LSCs in AML, and provided a promising anti-leukemia approach by interrupting FGFR3.
Tue Feb 16 00:00:00 EST 2021
Glucocorticoids Promote the Onset of Acute Experimental Colitis and Cancer by Upregulating mTOR Signaling in Intestinal Epithelial Cells.
Cancers
Zhang Z,Dong L,Jia A,Chen X,Yang Q,Wang Y,Wang Y,Liu R,Cao Y,He Y,Bi Y,Liu G
17-5931 was used in Flow cytometry/Cell sorting to indicate that glucocorticoid-induced mTOR signaling in epithelial cells is required in the early stages of acute ulcerative colitis by modulating the dynamics of innate immune cell recruitment and activation.
Sat Apr 11 00:00:00 EDT 2020
Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross.
Cell reports
Martin MD,Sompallae R,Winborn CS,Harty JT,Badovinac VP
17-5931 was used in Flow cytometry/Cell sorting to advance the utility of the Collaborative Cross (CC) as a tool to analyze the immune response to viral infection.
Tue Apr 14 00:00:00 EDT 2020
Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease.
Nature communications
Lang J,Bohn P,Bhat H,Jastrow H,Walkenfort B,Cansiz F,Fink J,Bauer M,Olszewski D,Ramos-Nascimento A,Duhan V,Friedrich SK,Becker KA,Krawczyk A,Edwards MJ,Burchert A,Huber M,Friebus-Kardash J,Göthert JR,Hardt C,Probst HC,Schumacher F,Köhrer K,Kleuser B,Babiychuk EB,Sodeik B,Seibel J,Greber UF,Lang PA,Gulbins E,Lang KS
17-5931-82 was used in Flow Cytometry to show that macrophages take up HSV-1 via endocytosis and transport the virions into multivesicular bodies (MVBs).
Thu Mar 12 00:00:00 EDT 2020
Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models.
Communications biology
Waaler J,Mygland L,Tveita A,Strand MF,Solberg NT,Olsen PA,Aizenshtadt A,Fauskanger M,Lund K,Brinch SA,Lycke M,Dybing E,Nygaard V,Bøe SL,Heintz KM,Hovig E,Hammarström C,Corthay A,Krauss S
17-5931 was used in Flow cytometry/Cell sorting to show that a specific small-molecule tankyrase inhibitor, G007-LK, decreases WNT/β-catenin and YAP signaling in the syngeneic murine B16-F10 and Clone M-3 melanoma models and sensitizes the tumors to anti-PD-1 immune checkpoint therapy.
Fri Apr 24 00:00:00 EDT 2020
Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing.
Nature
Mahmoudi S,Mancini E,Xu L,Moore A,Jahanbani F,Hebestreit K,Srinivasan R,Li X,Devarajan K,Prélot L,Ang CE,Shibuya Y,Benayoun BA,Chang ALS,Wernig M,Wysocka J,Longaker MT,Snyder MP,Brunet A
17-5931 was used in Flow cytometry/Cell sorting to show that this variability may reflect distinct stochastic ageing trajectories between individuals, and could help in developing personalized strategies to improve iPS cell generation and wound healing in elderly individuals.
Tue Oct 01 00:00:00 EDT 2019
Neutrophils contribute to spontaneous resolution of liver inflammation and fibrosis via microRNA-223.
The Journal of clinical investigation
Calvente CJ,Tameda M,Johnson CD,Del Pilar H,Lin YC,Adronikou N,De Mollerat Du Jeu X,Llorente C,Boyer J,Feldstein AE
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Thu Jul 11 00:00:00 EDT 2019
Activation of JAK/STAT Signaling in Megakaryocytes Sustains Myeloproliferation In Vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research
Woods B,Chen W,Chiu S,Marinaccio C,Fu C,Gu L,Bulic M,Yang Q,Zouak A,Jia S,Suraneni PK,Xu K,Levine RL,Crispino JD,Wen QJ
17-5931 was used in Flow cytometry/Cell sorting to study the role of JAK/STAT signalling in megakaryocyte myeloproliferation.
Tue Oct 01 00:00:00 EDT 2019
Alcohol-induced adipose tissue macrophage phenotypic switching is independent of myeloid Toll-like receptor 4 expression.
American journal of physiology. Cell physiology
Fulham MA,Ratna A,Gerstein RM,Kurt-Jones EA,Mandrekar P
17-5931 was used in Flow cytometry/Cell sorting to determine the role of the innate immune receptor Toll-like receptor 4 (TLR4) in alcohol-induced adipose tissue inflammation.
Tue Oct 01 00:00:00 EDT 2019
Neutrophil extracellular traps induced by VP1 contribute to pulmonary edema during EV71 infection.
Cell death discovery
Wang N,Yang X,Sun J,Sun Z,Ma Q,Wang Z,Chen Z,Wang Z,Hu F,Wang H,Zhou L,Zhang M,Xu J
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Wed Sep 30 00:00:00 EDT 2020
ImmGen report: sexual dimorphism in the immune system transcriptome.
Nature communications
Gal-Oz ST,Maier B,Yoshida H,Seddu K,Elbaz N,Czysz C,Zuk O,Stranger BE,Ner-Gaon H,Shay T
17-5931 was used in Flow cytometry/Cell sorting to show transcriptional sexual dimorphism in macrophages.
Fri Sep 20 00:00:00 EDT 2019
m6A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment.
Cell reports
Cheng Y,Luo H,Izzo F,Pickering BF,Nguyen D,Myers R,Schurer A,Gourkanti S,Brüning JC,Vu LP,Jaffrey SR,Landau DA,Kharas MG
17-5931-82 was used in Flow cytometry/Cell sorting to indicate that RNA methylation controls symmetric commitment and cell identity of hematopoietic stem cells and may provide a general mechanism for how stem cells regulate differentiation fate choice.
Tue Aug 13 00:00:00 EDT 2019
Pollen-derived RNAs Are Found in the Human Circulation.
iScience
Koupenova M,Mick E,Corkrey HA,Singh A,Tanriverdi SE,Vitseva O,Levy D,Keeler AM,Ezzaty Mirhashemi M,ElMallah MK,Gerstein M,Rozowsky J,Tanriverdi K,Freedman JE
17-5931 was used in Immunofluorescence to demonstrate that pollen-derived plant miRNAs can be horizontally transferred into the circulation via the pulmonary system in humans.
Fri Sep 27 00:00:00 EDT 2019
Bacteroides fragilis polysaccharide A induces IL-10 secreting B and T cells that prevent viral encephalitis.
Nature communications
Ramakrishna C,Kujawski M,Chu H,Li L,Mazmanian SK,Cantin EM
17-5931 was used in Flow cytometry/Cell sorting to study polysaccharide A as an immunomodulatory symbiosis factor whcih coordinates anti-inflammatory responses during viral infections.
Tue May 14 00:00:00 EDT 2019
Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia.
Nature communications
Minuesa G,Albanese SK,Xie W,Kazansky Y,Worroll D,Chow A,Schurer A,Park SM,Rotsides CZ,Taggart J,Rizzi A,Naden LN,Chou T,Gourkanti S,Cappel D,Passarelli MC,Fairchild L,Adura C,Glickman JF,Schulman J,Famulare C,Patel M,Eibl JK,Ross GM,Bhattacharya S,Tan DS,Leslie CS,Beuming T,Patel DJ,Goldgur Y,Chodera JD,Kharas MG
17-5931-82 was used in Flow Cytometry to study the role and mechanism of MUSASHI family RNA binding proteins in acute myeloid leukemia.
Wed Jun 19 00:00:00 EDT 2019
Nidogen-1 Contributes to the Interaction Network Involved in Pro-B Cell Retention in the Peri-sinusoidal Hematopoietic Stem Cell Niche.
Cell reports
Balzano M,De Grandis M,Vu Manh TP,Chasson L,Bardin F,Farina A,Sergé A,Bidaut G,Charbord P,Hérault L,Bailly AL,Cartier-Michaud A,Boned A,Dalod M,Duprez E,Genever P,Coles M,Bajenoff M,Xerri L,Aurrand-Lions M,Schiff C,Mancini SJC
17-5931 was used in Flow cytometry/Cell sorting to study pro-B cells in their support of stroll cells and their interaction network allowing their retention.
Tue Mar 19 00:00:00 EDT 2019
Novel charged sodium and calcium channel inhibitor active against neurogenic inflammation.
eLife
Lee S,Jo S,Talbot S,Zhang HB,Kotoda M,Andrews NA,Puopolo M,Liu PW,Jacquemont T,Pascal M,Heckman LM,Jain A,Lee J,Woolf CJ,Bean BP
17-5931-82 was used in Flow Cytometry to show that some cationic molecules applied extracellularly can powerfully inhibit both sodium channels and calcium channels, thereby blocking both nociceptor excitability and pro-inflammatory peptide release.
Mon Nov 25 00:00:00 EST 2019
The role of platelets in mediating a response to human influenza infection.
Nature communications
Koupenova M,Corkrey HA,Vitseva O,Manni G,Pang CJ,Clancy L,Yao C,Rade J,Levy D,Wang JP,Finberg RW,Kurt-Jones EA,Freedman JE
17-5931 was used in Immunocytochemistry-immunoflourescence to determine if platelet processes are activated during influenza infection.
Tue Apr 16 00:00:00 EDT 2019
E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.
Immunity
Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Tue Feb 20 00:00:00 EST 2018
A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion.
Immunity
Xia P,Wang S,Ye B,Du Y,Li C,Xiong Z,Qu Y,Fan Z
17-5931 was used in Flow cytometry/Cell sorting to study circular RNA-mediated maintenance of hematopoeitic stem cell homeostasis.
Tue Apr 17 00:00:00 EDT 2018
Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages.
Breast cancer research : BCR
Donzelli S,Milano E,Pruszko M,Sacconi A,Masciarelli S,Iosue I,Melucci E,Gallo E,Terrenato I,Mottolese M,Zylicz M,Zylicz A,Fazi F,Blandino G,Fontemaggi G
17-5931 was used in Flow cytometry/Cell sorting to investigate whether ID4 exerts its pro-angiogenic function while also modulating the activity of tumour-associated macrophages in breast cancer.
Tue Jun 19 00:00:00 EDT 2018
Prophylactic Antiheparanase Activity by PG545 Is Antiviral In Vitro and Protects against Ross River Virus Disease in Mice.
Antimicrobial agents and chemotherapy
Supramaniam A,Liu X,Ferro V,Herrero LJ
17-5931 was used in Flow cytometry/Cell sorting to describe both prophylactic and therapeutic treatment with PG545, a low-molecular-weight heparan sulfate mimetic, for arthritogenic alphaviral infection.
Sun Apr 01 00:00:00 EDT 2018
Intraperitoneal neutrophils activated by KRAS-induced ovarian cancer exert antitumor effects by modulating adaptive immunity.
International journal of oncology
Yoshida M,Taguchi A,Kawana K,Ogishima J,Adachi K,Kawata A,Nakamura H,Sato M,Fujimoto A,Inoue T,Tomio K,Mori M,Nagamatsu T,Arimoto T,Koga K,Hiraike OW,Oda K,Kiyono T,Osuga Y,Fujii T
17-5931 was used in Flow cytometry/Cell sorting to evaluate the role of increased neutrophils in cancer progression.
Mon Oct 01 00:00:00 EDT 2018
Investigation of tumor-tumor interactions in a double human cervical carcinoma xenograft model in nude mice.
Oncotarget
Mertens B,Cristina de Araujo Nogueira T,Topalis D,Stranska R,Snoeck R,Andrei G
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Tue Apr 24 00:00:00 EDT 2018
Antiviral effects of ferric ammonium citrate.
Cell discovery
Wang H,Li Z,Niu J,Xu Y,Ma L,Lu A,Wang X,Qian Z,Huang Z,Jin X,Leng Q,Wang J,Zhong J,Sun B,Meng G
Tue Sep 29 00:00:00 EDT 2020
Induction of neutrophil apoptosis by a Bcl-2 inhibitor reduces particulate matter-induced lung inflammation.
Aging
Geng X,Wang X,Luo M,Xing M,Wu Y,Li W,Chen Z,Shen H,Ying S
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Tue Jun 26 00:00:00 EDT 2018
Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice.
mSphere
Quach D,Collins F,Parameswaran N,McCabe L,Britton RA
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Targeting immune checkpoints potentiates immunoediting and changes the dynamics of tumor evolution.
Nature communications
Efremova M,Rieder D,Klepsch V,Charoentong P,Finotello F,Hackl H,Hermann-Kleiter N,Löwer M,Baier G,Krogsdam A,Trajanoski Z
17-5931 was used in Flow cytometry/Cell sorting to demonstrate that neutral evolution is another force that contributes to sculpting the tumor and that checkpoint blockade effectively enforces T-cell-dependent immunoselective pressure.
Tue Jan 02 00:00:00 EST 2018
Yolk sac macrophage progenitors traffic to the embryo during defined stages of development.
Nature communications
Stremmel C,Schuchert R,Wagner F,Thaler R,Weinberger T,Pick R,Mass E,Ishikawa-Ankerhold HC,Margraf A,Hutter S,Vagnozzi R,Klapproth S,Frampton J,Yona S,Scheiermann C,Molkentin JD,Jeschke U,Moser M,Sperandio M,Massberg S,Geissmann F,Schulz C
17-5931 was used in Flow cytometry/Cell sorting to close an important gap in our understanding of the development of the innate immune system.
Mon Jan 08 00:00:00 EST 2018
AMPK Activation Regulates LTBP4-Dependent TGF-β1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy.
Cell reports
Juban G,Saclier M,Yacoub-Youssef H,Kernou A,Arnold L,Boisson C,Ben Larbi S,Magnan M,Cuvellier S,Théret M,Petrof BJ,Desguerre I,Gondin J,Mounier R,Chazaud B
17-5931 was used in Flow cytometry/Cell sorting to conclude that an AMPK-LTBP4 axis in inflammatory macrophages controls the production of TGF-β1, which is further activated by and acts on fibroblastic cells, leading to fibrosis in DMD.
Tue Nov 20 00:00:00 EST 2018
Mesenchymal Stromal Cells Directly Promote Inflammation by Canonical NLRP3 and Non-canonical Caspase-11 Inflammasomes.
EBioMedicine
Chen Y,Qin X,An Q,Yi J,Feng F,Yin D,An N,Liu Z,Weng L,Chen S,Hu X,Yin W
17-5931 was used in Flow cytometry/Cell sorting to demonstrate that canonical NLRP3 and non-canonical caspase-11 inflammasomes were activated in bone-associated mesenchymal stromal cells to promote the inflammatory response.
Fri Jun 01 00:00:00 EDT 2018
CCR2+ Monocyte-Derived Infiltrating Macrophages Are Required for Adverse Cardiac Remodeling During Pressure Overload.
JACC. Basic to translational science
Patel B,Bansal SS,Ismahil MA,Hamid T,Rokosh G,Mack M,Prabhu SD
17-5931 was used in Flow cytometry/Cell sorting to demonstrate that monocyte-derived C-C chemokine receptor 2 macrophages infiltrate the heart early during pressure overload in mice and blocking this response alleviates cardiac fibrosis..
Sun Apr 01 00:00:00 EDT 2018
Dual Strategies for Argonaute2-Mediated Biogenesis of Erythroid miRNAs Underlie Conserved Requirements for Slicing in Mammals.
Molecular cell
Jee D,Yang JS,Park SM,Farmer DT,Wen J,Chou T,Chow A,McManus MT,Kharas MG,Lai EC
17-5931-82 was used in flow cytometry to investigate erythroid miRNA biogenesis in mammalian slicing.
Thu Jan 18 00:00:00 EST 2018
Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.
Nature communications
Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS
17-5931 was used in Flow cytometry/Cell sorting to characterise the expression signature that distinguishes arterial endothelial cells from sinusoidal endothelial cells.
Fri Jun 22 00:00:00 EDT 2018
The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia.
Nature medicine
Fenouille N,Bassil CF,Ben-Sahra I,Benajiba L,Alexe G,Ramos A,Pikman Y,Conway AS,Burgess MR,Li Q,Luciano F,Auberger P,Galinsky I,DeAngelo DJ,Stone RM,Zhang Y,Perkins AS,Shannon K,Hemann MT,Puissant A,Stegmaier K
17-5931 was used in Flow cytometry/Cell sorting to investigate the effect of MECOM on cellular metabolism.
Wed Mar 01 00:00:00 EST 2017
Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation.
Cell
Wang S,Xia P,Chen Y,Qu Y,Xiong Z,Ye B,Du Y,Tian Y,Yin Z,Xu Z,Fan Z
17-5931 was used in Flow cytometry/Cell sorting to identify a regulatory subpopulation of innate lymphoid cells that exists in the gut, and harbour a unique gene identity.
Thu Sep 21 00:00:00 EDT 2017
TRIB3 Promotes APL Progression through Stabilization of the Oncoprotein PML-RARα and Inhibition of p53-Mediated Senescence.
Cancer cell
Li K,Wang F,Cao WB,Lv XX,Hua F,Cui B,Yu JJ,Zhang XW,Shang S,Liu SS,Yu JM,Han MZ,Huang B,Zhang TT,Li X,Jiang JD,Hu ZW
17-5931 was used in Flow cytometry/Cell sorting to study acute promyelocytic leukaemia pathogenesis and elucidate a potential therapeutic option.
Mon May 08 00:00:00 EDT 2017
Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo.
Cancer cell
Leanza L,Romio M,Becker KA,Azzolini M,Trentin L,Managò A,Venturini E,Zaccagnino A,Mattarei A,Carraretto L,Urbani A,Kadow S,Biasutto L,Martini V,Severin F,Peruzzo R,Trimarco V,Egberts JH,Hauser C,Visentin A,Semenzato G,Kalthoff H,Zoratti M,Gulbins E,Paradisi C,Szabo I
17-5931 was used in Flow cytometry/Cell sorting to demonstrate that specific pharmacological targeting of a mitochondrial potassium channel can lead to reactive oxygen species-mediated selective apoptosis of cancer cells in vivo, without significant side effects.
Mon Apr 10 00:00:00 EDT 2017
Myeloid Cell-Derived Reactive Oxygen Species Induce Epithelial Mutagenesis.
Cancer cell
Canli Ö,Nicolas AM,Gupta J,Finkelmeier F,Goncharova O,Pesic M,Neumann T,Horst D,Löwer M,Sahin U,Greten FR
17-5931 was used in Flow cytometry/Cell sorting to identify a crosstalk between myeloid cell-derived reactive oxygen species molecules, oxidative DNA damage and tumour necrosis factor α-mediated signalling to orchestrate a tumour-promoting microenvironment causing invasive cancer.
Mon Dec 11 00:00:00 EST 2017
Differential cytokine contributions of perivascular haematopoietic stem cell niches.
Nature cell biology
Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS
17-5931 was used in Flow cytometry/Cell sorting to demonstrate that the effects of cytokines regulating haematopoietic stem cell functions are dependent on the producing cell sources.
Wed Mar 01 00:00:00 EST 2017
ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control.
The Journal of experimental medicine
Schwartz C,Khan AR,Floudas A,Saunders SP,Hams E,Rodewald HR,McKenzie ANJ,Fallon PG
17-5931 was used in Flow cytometry/Cell sorting to study how group 2 innate lymphoid cells regulate adaptive Th2 cell functions.
Mon Sep 04 00:00:00 EDT 2017
Brd4 modulates the innate immune response through Mnk2-eIF4E pathway-dependent translational control of IκBα.
Proceedings of the National Academy of Sciences of the United States of America
Bao Y,Wu X,Chen J,Hu X,Zeng F,Cheng J,Jin H,Lin X,Chen LF
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Tue May 16 00:00:00 EDT 2017
Streptococcus pneumoniae in the heart subvert the host response through biofilm-mediated resident macrophage killing.
PLoS pathogens
Shenoy AT,Brissac T,Gilley RP,Kumar N,Wang Y,Gonzalez-Juarbe N,Hinkle WS,Daugherty SC,Shetty AC,Ott S,Tallon LJ,Deshane J,Tettelin H,Orihuela CJ
17-5931 was used in Flow cytometry/Cell sorting to show that biofilm pneumococci actively suppress the host response through pneumolysin-mediated immune cell killing.
Tue Aug 01 00:00:00 EDT 2017
Retinoic Acid Regulates Immune Responses by Promoting IL-22 and Modulating S100 Proteins in Viral Hepatitis.
Journal of immunology (Baltimore, Md. : 1950)
Jie Z,Liang Y,Yi P,Tang H,Soong L,Cong Y,Zhang K,Sun J
17-5931 was used in Flow cytometry/Cell sorting to determine the role of retinoic acid in IL-22 production during hepatitis infection.
Mon May 01 00:00:00 EDT 2017
Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-κB signaling and NLRP3 activation.
International journal of molecular medicine
Zhang B,Wang B,Cao S,Wang Y,Wu D
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
Reducing Inflammatory Cytokine Production from Renal Collecting Duct Cells by Inhibiting GATA2 Ameliorates Acute Kidney Injury.
Molecular and cellular biology
Yu L,Moriguchi T,Kaneko H,Hayashi M,Hasegawa A,Nezu M,Saya H,Yamamoto M,Shimizu R
17-5931 was used in Flow cytometry/Cell sorting to study a novel pathological mechanism of renal ischaemia-reperfusion injury.
Wed Nov 15 00:00:00 EST 2017
ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.
RNA biology
Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M
17-5931 was used in Flow cytometry/Cell sorting to study the regulatory role of ADAR1 in hepatic immune homeostasis.
Thu May 04 00:00:00 EDT 2017
Differential effect of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) on leukocyte infiltration during contact hypersensitivity responses.
PeerJ
Early M,Schroeder WG,Unnithan R,Gilchrist JM,Muller WA,Schenkel A
17-5931 was used in Flow cytometry/Cell sorting to examine the role of PECAM-1 in the migration capacity of several different leukocyte populations after primary and secondary application.
Mon Dec 14 00:00:00 EST 2020
MiR-125a Is a critical modulator for neutrophil development.
PLoS genetics
Qin Y,Wu L,Ouyang Y,Zhou P,Zhou H,Wang Y,Ma J,Zhang J,Chen Y,Qian J,Tang Y,Shen N
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells.
Oncotarget
Guo XL,Chu L,Ke F,Mu LL,Li Z,Cai JJ,Li HF,Hong DL
Tue Dec 12 00:00:00 EST 2017
BOT-4-one attenuates NLRP3 inflammasome activation: NLRP3 alkylation leading to the regulation of its ATPase activity and ubiquitination.
Scientific reports
Shim DW,Shin WY,Yu SH,Kim BH,Ye SK,Koppula S,Won HS,Kang TB,Lee KH
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Wed Nov 08 00:00:00 EST 2017
Human Neutrophil Peptide 1 Limits Hypercholesterolemia-induced Atherosclerosis by Increasing Hepatic LDL Clearance.
EBioMedicine
Paulin N,Döring Y,Kooijman S,Blanchet X,Viola JR,de Jong R,Mandl M,Hendrikse J,Schiener M,von Hundelshausen P,Vogt A,Weber C,Bdeir K,Hofmann SM,Rensen PCN,Drechsler M,Soehnlein O
17-5931 was used in Flow cytometry/Cell sorting to study the role of human neutrophil peptide 1 in a mouse model of atherosclerosis and identify its therapeutic potential.
Wed Feb 01 00:00:00 EST 2017
Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles.
Scientific reports
Costa-Gouveia J,Pancani E,Jouny S,Machelart A,Delorme V,Salzano G,Iantomasi R,Piveteau C,Queval CJ,Song OR,Flipo M,Deprez B,Saint-André JP,Hureaux J,Majlessi L,Willand N,Baulard A,Brodin P,Gref R
17-5931 was used in Flow cytometry/Cell sorting to pave the way for a future use of pCD NPs for the pulmonary delivery of the [ETH:Booster] pair in TB chemotherapy.
Fri Jul 14 00:00:00 EDT 2017
In vitro Demonstration and Quantification of Neutrophil Extracellular Trap Formation.
Bio-protocol
Jiang D,Saffarzadeh M,Scharffetter-Kochanek K
17-5931-82 was used in flow cytometry to describe easy methods to demonstrate NET formation by immunofluorescence staining of extracellular chromatin fiber with anti-DNA/Histone H1 antibody and quantification of NETs by using a non-cell-permeable DNA specific dye Sytox orange.
Wed Jul 05 00:00:00 EDT 2017
The impact of environmental enrichment on the murine inflammatory immune response.
JCI insight
Brod S,Gobbetti T,Gittens B,Ono M,Perretti M,D'Acquisto F
17-5931 was used in Flow Cytometry to investigate the impact of environmental enrichment on the murine inflammatory immune response.
Thu Apr 06 00:00:00 EDT 2017
Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates.
Nature biotechnology
Vegas AJ,Veiseh O,Doloff JC,Ma M,Tam HH,Bratlie K,Li J,Bader AR,Langan E,Olejnik K,Fenton P,Kang JW,Hollister-Locke J,Bochenek MA,Chiu A,Siebert S,Tang K,Jhunjhunwala S,Aresta-Dasilva S,Dholakia N,Thakrar R,Vietti T,Chen M,Cohen J,Siniakowicz K,Qi M,McGarrigle J,Graham AC,Lyle S,Harlan DM,Greiner DL,Oberholzer J,Weir GC,Langer R,Anderson DG
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Thu Aug 25 00:00:00 EDT 2016
Multiple myeloma exosomes establish a favourable bone marrow microenvironment with enhanced angiogenesis and immunosuppression.
The Journal of pathology
Wang J,De Veirman K,Faict S,Frassanito MA,Ribatti D,Vacca A,Menu E
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth.
Stem cells translational medicine
Zheng H,Zou W,Shen J,Xu L,Wang S,Fu YX,Fan W
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.
Immunology
Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Sat Oct 01 00:00:00 EDT 2016
G-CSF-Induced Suppressor IL-10+ Neutrophils Promote Regulatory T Cells That Inhibit Graft-Versus-Host Disease in a Long-Lasting and Specific Way.
Journal of immunology (Baltimore, Md. : 1950)
Perobelli SM,Mercadante AC,Galvani RG,Gonçalves-Silva T,Alves AP,Pereira-Neves A,Benchimol M,Nóbrega A,Bonomo A
17-5931 was used in Flow cytometry/Cell sorting to study the role of incoming IL-10+ neutrophils from G-CSF-treated donor spleen in inhibiting acute graft-versus-host disease.
Tue Nov 01 00:00:00 EDT 2016
The miR-17∼92 cluster contributes to MLL leukemia through the repression of MEIS1 competitor PKNOX1.
Leukemia research
Mian YA,Zeleznik-Le NJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Fri Jul 01 00:00:00 EDT 2016
Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.
Stem cell reports
Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Tue Aug 09 00:00:00 EDT 2016
Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury.
Cell death & disease
Di Siena S,Gimmelli R,Nori SL,Barbagallo F,Campolo F,Dolci S,Rossi P,Venneri MA,Giannetta E,Gianfrilli D,Feigenbaum L,Lenzi A,Naro F,Cianflone E,Mancuso T,Torella D,Isidori AM,Pellegrini M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Thu Jul 28 00:00:00 EDT 2016
Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice.
BMC genomics
Leist SR,Pilzner C,van den Brand JM,Dengler L,Geffers R,Kuiken T,Balling R,Kollmus H,Schughart K
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Sat Feb 27 00:00:00 EST 2016
Enterococcus durans TN-3 Induces Regulatory T Cells and Suppresses the Development of Dextran Sulfate Sodium (DSS)-Induced Experimental Colitis.
PloS one
Kanda T,Nishida A,Ohno M,Imaeda H,Shimada T,Inatomi O,Bamba S,Sugimoto M,Andoh A
17-5931 was used in Flow cytometry/Cell sorting to investigate the effects of E. durans TN-3 on the development of dextran sulfate sodium colitis.
Fri Jul 21 00:00:00 EDT 2017
Allergy Enhances Neurogenesis and Modulates Microglial Activation in the Hippocampus.
Frontiers in cellular neuroscience
Klein B,Mrowetz H,Thalhamer J,Scheiblhofer S,Weiss R,Aigner L
17-5931 was used in Flow cytometry/Cell sorting to investigate the effects of allergic lung inflammation on the hippocampus in mice clinically sensitised with a grass pollen allergen.
Fri Jul 22 00:00:00 EDT 2016
Modification of the Tumor Microenvironment in KRAS or c-MYC-Induced Ovarian Cancer-Associated Peritonitis.
PloS one
Yoshida M,Taguchi A,Kawana K,Adachi K,Kawata A,Ogishima J,Nakamura H,Fujimoto A,Sato M,Inoue T,Nishida H,Furuya H,Tomio K,Arimoto T,Koga K,Wada-Hiraike O,Oda K,Nagamatsu T,Kiyono T,Osuga Y,Fujii T
17-5931 was used in Flow cytometry/Cell sorting to suggest that oncogenes promote cancer progression by modulating the tumour microenvironment in favor of cancer progression.
Wed Jul 26 00:00:00 EDT 2017
Modification of the Tumor Microenvironment in KRAS or c-MYC-Induced Ovarian Cancer-Associated Peritonitis.
PloS one
Yoshida M,Taguchi A,Kawana K,Adachi K,Kawata A,Ogishima J,Nakamura H,Fujimoto A,Sato M,Inoue T,Nishida H,Furuya H,Tomio K,Arimoto T,Koga K,Wada-Hiraike O,Oda K,Nagamatsu T,Kiyono T,Osuga Y,Fujii T
17-5931 was used in Flow cytometry/Cell sorting to suggest that oncogenes promote cancer progression by modulating the tumour microenvironment in favor of cancer progression.
Wed Jul 26 00:00:00 EDT 2017
MEK1 is required for the development of NRAS-driven leukemia.
Oncotarget
Nowacka JD,Baumgartner C,Pelorosso C,Roth M,Zuber J,Baccarini M
17-5931 was used in Flow cytometry/Cell sorting to consider the use of MEK1 as a tumour suppressor in the context of leukaemogenesis.
Tue Dec 06 00:00:00 EST 2016
mRNA-Mediated Gene Supplementation of Toll-Like Receptors as Treatment Strategy for Asthma In Vivo.
PloS one
Zeyer F,Mothes B,Will C,Carevic M,Rottenberger J,Nürnberg B,Hartl D,Handgretinger R,Beer-Hammer S,Kormann MS
17-5931 was used in Flow cytometry/Cell sorting to investigate the effect of a preventative treatment with combinations of Tlr1, Tlr2 and Tlr6 mRNA in a House Dust Mite-induced mouse model of asthma.
Mon Mar 13 00:00:00 EDT 2017
Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors.
Nature communications
Cheng H,Ang HY,A El Farran C,Li P,Fang HT,Liu TM,Kong SL,Chin ML,Ling WY,Lim EK,Li H,Huber T,Loh KM,Loh YH,Lim B
17-5931 was used in Flow cytometry/Cell sorting to demonstrate how it is possible to reprogram mouse embryonic fibroblasts into engraftable blood progenitors.
Mon Nov 21 00:00:00 EST 2016
Pro-inflammatory effect of a traditional Chinese medicine formula with potent anti-cancer activity in vitro impedes tumor inhibitory potential in vivo.
Molecular and clinical oncology
Xia L,Plachynta M,Liu T,Xiao X,Song J,Li X,Zhang M,Yao Y,Luo H,Hao X,Ben-David Y
17-5931 was used in Flow cytometry/Cell sorting to highlight the complexity of Chinese medicinal compounds and the need to thoroughly analyze their systemic effects at high concentrations in vivo.
Thu Dec 01 00:00:00 EST 2016
Induction of Chronic Myeloid Leukemia in Mice.
Methods in molecular biology (Clifton, N.J.)
Zhang H,Li S
17-5931-82 was used in Flow cytometry/Cell sorting to describe methods for induction of CML in mice with BCR-ABL.
Fri Jan 26 00:00:00 EST 2018
The BRAF pseudogene functions as a competitive endogenous RNA and induces lymphoma in vivo.
Cell
Karreth FA,Reschke M,Ruocco A,Ng C,Chapuy B,Léopold V,Sjoberg M,Keane TM,Verma A,Ala U,Tay Y,Wu D,Seitzer N,Velasco-Herrera Mdel C,Bothmer A,Fung J,Langellotto F,Rodig SJ,Elemento O,Shipp MA,Adams DJ,Chiarle R,Pandolfi PP
17-5931 was used in Flow cytometry/Cell sorting to find that transcriptional or genomic aberrations of BRAFP1 occur frequently in multiple human cancers, including B cell lymphomas.
Thu Apr 09 00:00:00 EDT 2015
P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy.
Cell research
Wang H,Hong LJ,Huang JY,Jiang Q,Tao RR,Tan C,Lu NN,Wang CK,Ahmed MM,Lu YM,Liu ZR,Shi WX,Lai EY,Wilcox CS,Han F
17-5931 was used in Flow cytometry/Cell sorting to demonstrate the role of the P2RX7 pathway in linking neurovascular inflammation to brain damage in vivo.
Mon Jun 01 00:00:00 EDT 2015
Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.
Blood
Matthews GM,Mehdipour P,Cluse LA,Falkenberg KJ,Wang E,Roth M,Santoro F,Vidacs E,Stanley K,House CM,Rusche JR,Vakoc CR,Zuber J,Minucci S,Johnstone RW
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Thu Nov 19 00:00:00 EST 2015
Phospholipid oxidation generates potent anti-inflammatory lipid mediators that mimic structurally related pro-resolving eicosanoids by activating Nrf2.
EMBO molecular medicine
Bretscher P,Egger J,Shamshiev A,Trötzmüller M,Köfeler H,Carreira EM,Kopf M,Freigang S
17-5931 was used in Flow cytometry/Cell sorting to provide a molecular basis for the negative regulation of inflammation by lipid peroxidation products and propose a novel class of highly bioactive compounds for the treatment of inflammatory diseases.
Fri May 01 00:00:00 EDT 2015
The transcriptional cofactor TRIM33 prevents apoptosis in B lymphoblastic leukemia by deactivating a single enhancer.
eLife
Wang E,Kawaoka S,Roe JS,Shi J,Hohmann AF,Xu Y,Bhagwat AS,Suzuki Y,Kinney JB,Vakoc CR
17-5931 was used in Flow cytometry/Cell sorting to reveal an essential role for TRIM33 in preventing apoptosis in B lymphoblastic leukaemia by interfering with enhancer-mediated Bim activation.
Tue Apr 28 00:00:00 EDT 2015
Circumventing Y. pestis Virulence by Early Recruitment of Neutrophils to the Lungs during Pneumonic Plague.
PLoS pathogens
Vagima Y,Zauberman A,Levy Y,Gur D,Tidhar A,Aftalion M,Shafferman A,Mamroud E
17-5931 was used in Flow cytometry/Cell sorting to investigate the mechanisms responsible for delayed neutrophil homing to the lungs during Pneumonic plague.
Fri May 01 00:00:00 EDT 2015
Pentosan Polysulfate: a Novel Glycosaminoglycan-Like Molecule for Effective Treatment of Alphavirus-Induced Cartilage Destruction and Inflammatory Disease.
Journal of virology
Herrero LJ,Foo SS,Sheng KC,Chen W,Forwood MR,Bucala R,Mahalingam S
17-5931 was used in Flow cytometry/Cell sorting to demonstrate the potential of glycotherapeutics as a new class of treatment for infectious arthritis.
Sat Aug 01 00:00:00 EDT 2015
Experimental design of complement component 5a-induced acute lung injury (C5a-ALI): a role of CC-chemokine receptor type 5 during immune activation by anaphylatoxin.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Russkamp NF,Ruemmler R,Roewe J,Moore BB,Ward PA,Bosmann M
17-5931 was used in Flow cytometry/Cell sorting to determine that the detrimental effects of C5a are partly mediated through CCR5 activation downstream of C5aR1.
Tue Sep 01 00:00:00 EDT 2015
Newly recruited CD11b+, GR-1+, Ly6C(high) myeloid cells augment tumor-associated immunosuppression immediately following the therapeutic administration of oncolytic reovirus.
Journal of immunology (Baltimore, Md. : 1950)
Clements DR,Sterea AM,Kim Y,Helson E,Dean CA,Nunokawa A,Coyle KM,Sharif T,Marcato P,Gujar SA,Lee PW
17-5931 was used in Flow cytometry/Cell sorting to demonstrate that reovirus augments tumour-associated immunosuppression immediately following its therapeutic administration.
Fri May 01 00:00:00 EDT 2015
A far-red fluorescent probe for flow cytometry and image-based functional studies of xenobiotic sequestering macrophages.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Keswani RK,Yoon GS,Sud S,Stringer KA,Rosania GR
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Local delivery of VEGF and SDF enhances endothelial progenitor cell recruitment and resultant recovery from ischemia.
Tissue engineering. Part A
Anderson EM,Kwee BJ,Lewin SA,Raimondo T,Mehta M,Mooney DJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Programmed cell death receptor ligand 1 modulates the regulatory T cells' capacity to repress shock/sepsis-induced indirect acute lung injury by recruiting phosphatase SRC homology region 2 domain-containing phosphatase 1.
Shock (Augusta, Ga.)
Tang L,Bai J,Chung CS,Lomas-Neira J,Chen Y,Huang X,Ayala A
17-5931 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which the programmed cell death receptor 1 ligand suppresses lung injury.
Thu Jan 01 00:00:00 EST 2015
Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway.
Molecular medicine reports
Huang L,Kong Y,Wang J,Sun J,Shi Q,Qiu YH
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
The bone marrow microenvironment enhances multiple myeloma progression by exosome-mediated activation of myeloid-derived suppressor cells.
Oncotarget
Wang J,De Veirman K,De Beule N,Maes K,De Bruyne E,Van Valckenborgh E,Vanderkerken K,Menu E
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Tue Dec 22 00:00:00 EST 2015
Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.
PloS one
Szulzewsky F,Pelz A,Feng X,Synowitz M,Markovic D,Langmann T,Holtman IR,Wang X,Eggen BJ,Boddeke HW,Hambardzumyan D,Wolf SA,Kettenmann H
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2016
Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts.
Stem cell reports
Neri T,Muggeo S,Paulis M,Caldana ME,Crisafulli L,Strina D,Focarelli ML,Faggioli F,Recordati C,Scaramuzza S,Scanziani E,Mantero S,Buracchi C,Sobacchi C,Lombardo A,Naldini L,Vezzoni P,Villa A,Ficara F
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Tue Oct 13 00:00:00 EDT 2015
Sunitinib depletes myeloid-derived suppressor cells and synergizes with a cancer vaccine to enhance antigen-specific immune responses and tumor eradication.
Oncoimmunology
Draghiciu O,Nijman HW,Hoogeboom BN,Meijerhof T,Daemen T
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2015
Neonatal microbial colonization in mice promotes prolonged dominance of CD11b(+)Gr-1(+) cells and accelerated establishment of the CD4(+) T cell population in the spleen.
Immunity, inflammation and disease
Kristensen MB,Metzdorff SB,Bergström A,Damlund DS,Fink LN,Licht TR,Frøkiær H
17-5931 was used in Flow cytometry/Cell sorting to assess the microbial influence on postnatal haematopoiesis.
Tue Sep 01 00:00:00 EDT 2015
Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury.
Nature communications
Ito M,Shichita T,Okada M,Komine R,Noguchi Y,Yoshimura A,Morita R
17-5931 was used in Flow cytometry/Cell sorting to report that Bruton's tyrosine kinase (BTK) is an essential component of the NLRP3 inflammasome, in which BTK physically interacts with ASC and NLRP3.
Wed Jun 10 00:00:00 EDT 2015
Hypoxia and TGF-β1 lead to endostatin resistance by cooperatively increasing cancer stem cells in A549 transplantation tumors.
Cell & bioscience
Wang Y,Jiang M,Li Z,Wang J,Du C,Yanyang L,Yu Y,Wang X,Zhang N,Zhao M,Wang L,Li M,Luo F
17-5931 was used in Flow cytometry/Cell sorting to investigate anti-tumour treatment using endostatin and mechanisms of resistance to the treatment.
Fri Dec 25 00:00:00 EST 2015
Standard sub-thermoneutral caging temperature influences radiosensitivity of hematopoietic stem and progenitor cells.
PloS one
Povinelli BJ,Kokolus KM,Eng JW,Dougher CW,Curtin L,Capitano ML,Sailsbury-Ruf CT,Repasky EA,Nemeth MJ
17-5931 was used in Flow cytometry/Cell sorting to demonstrate that chronic stress of laboratory mice increases the resistance of hematopoietic stem and progenitor cells to irradiation-induced apoptosis.
Tue Feb 09 00:00:00 EST 2016
Host adaptation of a bacterial toxin from the human pathogen Salmonella Typhi.
Cell
Deng L,Song J,Gao X,Wang J,Yu H,Chen X,Varki N,Naito-Matsui Y,Galán JE,Varki A
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Thu Dec 04 00:00:00 EST 2014
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
Nature immunology
Franklin BS,Bossaller L,De Nardo D,Ratter JM,Stutz A,Engels G,Brenker C,Nordhoff M,Mirandola SR,Al-Amoudi A,Mangan MS,Zimmer S,Monks BG,Fricke M,Schmidt RE,Espevik T,Jones B,Jarnicki AG,Hansbro PM,Busto P,Marshak-Rothstein A,Hornemann S,Aguzzi A,Kastenmüller W,Latz E
17-5931 was used in Flow cytometry/Cell sorting to study the behaviour of ASC specks and their contribution to IL-1β - induced inflammation.
Fri Aug 01 00:00:00 EDT 2014
Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain.
The Journal of clinical investigation
Old EA,Nadkarni S,Grist J,Gentry C,Bevan S,Kim KW,Mogg AJ,Perretti M,Malcangio M
17-5931 was used in Flow cytometry/Cell sorting to delineate a pathway for pain that is induced by the chemotherapeutic drug vincristine sulphate.
Thu May 01 00:00:00 EDT 2014
Myeloid-derived suppressor cell function is diminished in aspirin-triggered allergic airway hyperresponsiveness in mice.
The Journal of allergy and clinical immunology
Shi M,Shi G,Tang J,Kong D,Bao Y,Xiao B,Zuo C,Wang T,Wang Q,Shen Y,Wang H,Funk CD,Zhou J,Yu Y
17-5931 was used in Flow cytometry/Cell sorting to characterise myeloid-derived suppressor cell accumulation and pathogenic functions in allergic airway inflammation mediated by COX-1 deficiency or aspirin treatment in mice.
Sat Nov 01 00:00:00 EDT 2014
Macrophages contribute to the cyclic activation of adult hair follicle stem cells.
PLoS biology
Castellana D,Paus R,Perez-Moreno M
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Mon Dec 01 00:00:00 EST 2014
Maresin 1 mitigates LPS-induced acute lung injury in mice.
British journal of pharmacology
Gong J,Wu ZY,Qi H,Chen L,Li HB,Li B,Yao CY,Wang YX,Wu J,Yuan SY,Yao SL,Shang Y
17-5931 was used in Flow cytometry/Cell sorting to demonstrate that high-dose MaR1 mitigates LPS-induced lung injury in mice by inhibiting neutrophil adhesions and decreasing pro-inflammatory cytokines levels.
Tue Jul 01 00:00:00 EDT 2014
Gemcitabine enhances the efficacy of reovirus-based oncotherapy through anti-tumour immunological mechanisms.
British journal of cancer
Gujar SA,Clements D,Dielschneider R,Helson E,Marcato P,Lee PW
17-5931 was used in Flow cytometry/Cell sorting to demonstrate that reovirus and gemcitabine combination treatment postpones peritoneal carcinomatosis development and prolongs the survival of cancer-bearing hosts.
Tue Jan 07 00:00:00 EST 2014
Diet-induced obesity promotes myelopoiesis in hematopoietic stem cells.
Molecular metabolism
Singer K,DelProposto J,Morris DL,Zamarron B,Mergian T,Maley N,Cho KW,Geletka L,Subbaiah P,Muir L,Martinez-Santibanez G,Lumeng CN
17-5931 was used in Flow cytometry/Cell sorting to demonstrate how metabolic signals potentiate leukocyte production and dietary priming of haematopoietic progenitors contributes to adipose tissue inflammation.
Mon Sep 01 00:00:00 EDT 2014
CD41 is a reliable identification and activation marker for murine basophils in the steady state and during helminth and malarial infections.
European journal of immunology
Bakocevic N,Claser C,Yoshikawa S,Jones LA,Chew S,Goh CC,Malleret B,Larbi A,Ginhoux F,de Lafaille MC,Karasuyama H,Renia L,Ng LG
17-5931 was used in Flow cytometry/Cell sorting to study the CD41 expression within basophils from the blood during both steady state and malarial inections within mice.
Sun Jun 01 00:00:00 EDT 2014
The plexin C1 receptor promotes acute inflammation.
European journal of immunology
König K,Marth L,Roissant J,Granja T,Jennewein C,Devanathan V,Schneider M,Köhler D,Zarbock A,Rosenberger P
17-5931 was used in Flow cytometry/Cell sorting to study the role of plexin C1 during the acute inflammatory response.
Mon Sep 01 00:00:00 EDT 2014
Active players in resolution of shock/sepsis induced indirect lung injury: immunomodulatory effects of Tregs and PD-1.
Journal of leukocyte biology
Tang L,Bai J,Chung CS,Lomas-Neira J,Chen Y,Huang X,Ayala A
17-5931 was used in Flow cytometry/Cell sorting to explore the ability of Tregs to modify the innate immune response induced by experimental iALI.
Sat Nov 01 00:00:00 EDT 2014
Yersinia pseudotuberculosis efficiently escapes polymorphonuclear neutrophils during early infection.
Infection and immunity
Westermark L,Fahlgren A,Fällman M
17-5931 was used in Flow cytometry/Cell sorting to analyse bacterium-immune cell interactions in the intestinal lymphoid tissues of mice during early Yersinia pseudotuberculosis infection.
Sat Mar 01 00:00:00 EST 2014
Anti-tumor innate immunity activated by intermittent metronomic cyclophosphamide treatment of 9L brain tumor xenografts is preserved by anti-angiogenic drugs that spare VEGF receptor 2.
Molecular cancer
Doloff JC,Chen CS,Waxman DJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Thu Jun 26 00:00:00 EDT 2014
Activation of NLRP3 inflammasome by crystalline structures via cell surface contact.
Scientific reports
Hari A,Zhang Y,Tu Z,Detampel P,Stenner M,Ganguly A,Shi Y
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Tue Dec 02 00:00:00 EST 2014
Stage-dependent and locus-specific role of histone demethylase Jumonji D3 (JMJD3) in the embryonic stages of lung development.
PLoS genetics
Li Q,Wang HY,Chepelev I,Zhu Q,Wei G,Zhao K,Wang RF
17-5931 was used in Western Blotting to provide molecular insights into the mechanisms by which Jmjd3 regulates gene expression in the embryonic stages of lung development.
Tue Jul 01 00:00:00 EDT 2014
Stage-dependent and locus-specific role of histone demethylase Jumonji D3 (JMJD3) in the embryonic stages of lung development.
PLoS genetics
Li Q,Wang HY,Chepelev I,Zhu Q,Wei G,Zhao K,Wang RF
17-5931 was used in Western Blotting to provide molecular insights into the mechanisms by which Jmjd3 regulates gene expression in the embryonic stages of lung development.
Tue Jul 01 00:00:00 EDT 2014
Usp16 contributes to somatic stem-cell defects in Down's syndrome.
Nature
Adorno M,Sikandar S,Mitra SS,Kuo A,Nicolis Di Robilant B,Haro-Acosta V,Ouadah Y,Quarta M,Rodriguez J,Qian D,Reddy VM,Cheshier S,Garner CC,Clarke MF
17-5931 was used in Flow cytometry/Cell sorting to demonstrate a role for USP16 in antagonising the self-renewal and senescence pathways in Down's syndrome.
Thu Sep 19 00:00:00 EDT 2013
Arteriolar niches maintain haematopoietic stem cell quiescence.
Nature
Kunisaki Y,Bruns I,Scheiermann C,Ahmed J,Pinho S,Zhang D,Mizoguchi T,Wei Q,Lucas D,Ito K,Mar JC,Bergman A,Frenette PS
17-5931 was used in Flow cytometry/Cell sorting to investigate the spatial localisation of quiescent haematopoietic stem cells in bone marrow, showing that arteriolar niches maintain quiescence.
Thu Oct 31 00:00:00 EDT 2013
A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation.
Blood
Brancaleone V,Gobbetti T,Cenac N,le Faouder P,Colom B,Flower RJ,Vergnolle N,Nourshargh S,Perretti M
17-5931 was used in Flow cytometry/Cell sorting to study the involvement of formyl peptide receptor 2 in postischemia reperfusion injury.
Thu Jul 25 00:00:00 EDT 2013
Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine production.
The Journal of allergy and clinical immunology
Doherty TA,Khorram N,Lund S,Mehta AK,Croft M,Broide DH
17-5931 was used in Flow cytometry/Cell sorting to determine if leukotrienes contribute to asthma pathogenesis by activating type 2 innate lymphoid cells and inducing interleukin production.
Mon Jul 01 00:00:00 EDT 2013
Dose-dense chemotherapy improves mechanisms of antitumor immune response.
Cancer research
Chang CL,Hsu YT,Wu CC,Lai YZ,Wang C,Yang YC,Wu TC,Hung CF
17-5931 was used in Flow cytometry/Cell sorting to assess whether a low or high dose DD combinatorial regimen of cisplatin and paclitaxel is more effective for the treatment of ovarian cancer.
Tue Jan 01 00:00:00 EST 2013
Multifaceted therapeutic targeting of ovarian peritoneal carcinomatosis through virus-induced immunomodulation.
Molecular therapy : the journal of the American Society of Gene Therapy
Gujar S,Dielschneider R,Clements D,Helson E,Shmulevitz M,Marcato P,Pan D,Pan LZ,Ahn DG,Alawadhi A,Lee PW
17-5931 was used in Flow cytometry/Cell sorting to develop a virus-based therapy that suppresses immunomodulation and targets ovarian peritoneal carcinomatosis.
Fri Feb 01 00:00:00 EST 2013
Sialyltransferase ST3Gal-III regulates Siglec-F ligand formation and eosinophilic lung inflammation in mice.
Journal of immunology (Baltimore, Md. : 1950)
Suzukawa M,Miller M,Rosenthal P,Cho JY,Doherty TA,Varki A,Broide D
17-5931 was used in Flow cytometry/Cell sorting to study the regulated murine expression of Siglec-F ligand in immune and lung airway epithelial cells.
Sat Jun 15 00:00:00 EDT 2013
Migration of CD11b+ accessory cells during murine lung regeneration.
Stem cell research
Chamoto K,Gibney BC,Lee GS,Ackermann M,Konerding MA,Tsuda A,Mentzer SJ
17-5931 was used in Flow cytometry/Cell sorting to characterise the factors contributing to neoalveolarization within 21 days of pneumonectomy.
Wed May 01 00:00:00 EDT 2013
The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects.
The Journal of biological chemistry
Zamanian-Daryoush M,Lindner D,Tallant TC,Wang Z,Buffa J,Klipfell E,Parker Y,Hatala D,Parsons-Wingerter P,Rayman P,Yusufishaq MSS,Fisher EA,Smith JD,Finke J,DiDonato JA,Hazen SL
17-5931 was used in Flow cytometry/Cell sorting to show that apolipoprotein A1 potently suppresses tumour growth and metastasis.
Fri Jul 19 00:00:00 EDT 2013
Macrophage migration inhibitory factor receptor CD74 mediates alphavirus-induced arthritis and myositis in murine models of alphavirus infection.
Arthritis and rheumatism
Herrero LJ,Sheng KC,Jian P,Taylor A,Her Z,Herring BL,Chow A,Leo YS,Hickey MJ,Morand EF,Ng LF,Bucala R,Mahalingam S
17-5931 was used in Flow cytometry/Cell sorting to investigate the role that CD74 plays in the immunopathogenesis of arthritic alphavirus infection and myositis in mice.
Tue Oct 01 00:00:00 EDT 2013
Methotrexate treatment causes early onset of disease in a mouse model of Ross River virus-induced inflammatory disease through increased monocyte production.
PloS one
Taylor A,Sheng KC,Herrero LJ,Chen W,Rulli NE,Mahalingam S
17-5931 was used in Flow cytometry/Cell sorting to study infiltration of inflammatory cells to skeletal muscle in Ross River virus disease in response to MTX treatment.
Thu Mar 06 00:00:00 EST 2014
NF-Y is necessary for hematopoietic stem cell proliferation and survival.
Blood
Bungartz G,Land H,Scadden DT,Emerson SG
17-5931 was used in Flow cytometry/Cell sorting to show that the trimeric transcription factor NF-Y is critical for the survival of cycling, but not quiescent hematopoietic stem cells.
Thu Feb 09 00:00:00 EST 2012
Dendritic cells tolerized with adenosine A₂AR agonist attenuate acute kidney injury.
The Journal of clinical investigation
Li L,Huang L,Ye H,Song SP,Bajwa A,Lee SJ,Moser EK,Jaworska K,Kinsey GR,Day YJ,Linden J,Lobo PI,Rosin DL,Okusa MD
17-5931 was used in Flow cytometry/Cell sorting to show that mice with A2AR-deficient dendritic cells are more susceptible to kidney ischemia/reperfusion injury.
Thu Nov 01 00:00:00 EDT 2012
Thymus-autonomous T cell development in the absence of progenitor import.
The Journal of experimental medicine
Martins VC,Ruggiero E,Schlenner SM,Madan V,Schmidt M,Fink PJ,von Kalle C,Rodewald HR
17-5931 was used in Flow cytometry/Cell sorting to characterise the previously unrecognised capacity of the thymus to sustain T cell development during bone marrow progenitor deprivation.
Mon Jul 30 00:00:00 EDT 2012
ZBTB1 is a determinant of lymphoid development.
The Journal of experimental medicine
Siggs OM,Li X,Xia Y,Beutler B
17-5931 was used in Flow cytometry/Cell sorting to identify a mutation causative of complete and cell-intrinsic T cell deficiency.
Mon Jan 16 00:00:00 EST 2012
Nuclear export of histone deacetylase 7 during thymic selection is required for immune self-tolerance.
The EMBO journal
Kasler HG,Lim HW,Mottet D,Collins AM,Lee IS,Verdin E
17-5931 was used in Flow cytometry/Cell sorting to examine the effect of blocking TCR-dependent nuclear export of HDAC7 during thymic selection, showing that HDAC7 is required for immune self-tolerance.
Wed Nov 28 00:00:00 EST 2012
Mechanisms of indirect acute lung injury: a novel role for the coinhibitory receptor, programmed death-1.
Annals of surgery
Monaghan SF,Thakkar RK,Heffernan DS,Huang X,Chung CS,Lomas-Neira J,Cioffi WG,Ayala A
17-5931 was used in Flow cytometry/Cell sorting to investigate how PD-1 expression contributes to mortality after the induction of indirect-acute lung injury.
Sun Jan 01 00:00:00 EST 2012
Differential gene expression in mice infected with distinct Toxoplasma strains.
Infection and immunity
Hill RD,Gouffon JS,Saxton AM,Su C
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2012
A model of GAG/MIP-2/CXCR2 interfaces and its functional effects.
Biochemistry
Rajasekaran D,Keeler C,Syed MA,Jones MC,Harrison JK,Wu D,Bhandari V,Hodsdon ME,Lolis EJ
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Tue Jul 17 00:00:00 EDT 2012
Virotherapy of canine tumors with oncolytic vaccinia virus GLV-1h109 expressing an anti-VEGF single-chain antibody.
PloS one
Patil SS,Gentschev I,Adelfinger M,Donat U,Hess M,Weibel S,Nolte I,Frentzen A,Szalay AA
17-5931 was used in Flow cytometry/Cell sorting to analyse oncolytic vaccinia virus-mediated delivery and production of scAb GLAF-1 and the oncolytic and immunological effects on canine cancer.
Thu Mar 28 00:00:00 EDT 2013
Virotherapy of canine tumors with oncolytic vaccinia virus GLV-1h109 expressing an anti-VEGF single-chain antibody.
PloS one
Patil SS,Gentschev I,Adelfinger M,Donat U,Hess M,Weibel S,Nolte I,Frentzen A,Szalay AA
17-5931 was used in Flow cytometry/Cell sorting to analyse oncolytic vaccinia virus-mediated delivery and production of scAb GLAF-1 and the oncolytic and immunological effects on canine cancer.
Thu Mar 28 00:00:00 EDT 2013
In vivo inhibition of c-MYC in myeloid cells impairs tumor-associated macrophage maturation and pro-tumoral activities.
PloS one
Pello OM,Chèvre R,Laoui D,De Juan A,Lolo F,Andrés-Manzano MJ,Serrano M,Van Ginderachter JA,Andrés V
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Mon Feb 25 00:00:00 EST 2013
Identification of myeloid derived suppressor cells in dogs with naturally occurring cancer.
PloS one
Goulart MR,Pluhar GE,Ohlfest JR
17-5931 was used in Flow cytometry/Cell sorting to analyse peripheral blood mononuclear cells from dogs with advanced or early stage cancer and from age-matched healthy controls.
Mon Aug 20 00:00:00 EDT 2012
Genomic expression analyses reveal lysosomal, innate immunity proteins, as disease correlates in murine models of a lysosomal storage disorder.
PloS one
Alam MS,Getz M,Safeukui I,Yi S,Tamez P,Shin J,Velázquez P,Haldar K
17-5931 was used in Flow cytometry/Cell sorting to identify Niemann-Pick Type C disease severity correlates, showing that expression of lysosomal, innate immunity proteins correlate with severity.
Mon Apr 01 00:00:00 EDT 2013
A microRNA encoded by Kaposi sarcoma-associated herpesvirus promotes B-cell expansion in vivo.
PloS one
Dahlke C,Maul K,Christalla T,Walz N,Schult P,Stocking C,Grundhoff A
17-5931 was used in Flow cytometry/Cell sorting to confirm and extend previous observations made in other mouse models, and underscore the notion that miR-K12-11 may have arisen to mimic miR-155 functions in KSHV-infected B-cells.
Wed May 22 00:00:00 EDT 2013
Early sensing of Yersinia pestis airway infection by bone marrow cells.
Frontiers in cellular and infection microbiology
Vagima Y,Levy Y,Gur D,Tidhar A,Aftalion M,Abramovich H,Zahavy E,Zauberman A,Flashner Y,Shafferman A,Mamroud E
17-5931 was used in Flow cytometry/Cell sorting to indicate that lung infection by Y. pestis is sensed by BM cells early after infection, although bacterial colonization of the BM occurs at late disease stages.
Wed Dec 11 00:00:00 EST 2013
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
Nature
Zuber J,Shi J,Wang E,Rappaport AR,Herrmann H,Sison EA,Magoon D,Qi J,Blatt K,Wunderlich M,Taylor MJ,Johns C,Chicas A,Mulloy JC,Kogan SC,Brown P,Valent P,Bradner JE,Lowe SW,Vakoc CR
17-5931 was used in Flow cytometry/Cell sorting to establish small-molecule inhibition of Brd4 as a promising therapeutic strategy in acute myeloid leukaemia.
Wed Aug 03 00:00:00 EDT 2011
RelA and RelB transcription factors in distinct thymocyte populations control lymphotoxin-dependent interleukin-17 production in γδ T cells.
Immunity
Powolny-Budnicka I,Riemann M,Tänzer S,Schmid RM,Hehlgans T,Weih F
17-5931 was used in Flow cytometry/Cell sorting to investigate the contribution of NF-κB to IL-17 production by T cells, showing that RelA and RelB in distinct thymocyte populations control lymphotoxin-dependent IL-17 production.
Fri Mar 25 00:00:00 EDT 2011
Genetic deletion of chemokine receptor Ccr6 decreases atherogenesis in ApoE-deficient mice.
Circulation research
Wan W,Lim JK,Lionakis MS,Rivollier A,McDermott DH,Kelsall BL,Farber JM,Murphy PM
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Fri Aug 05 00:00:00 EDT 2011
Virus-induced tumor inflammation facilitates effective DC cancer immunotherapy in a Treg-dependent manner in mice.
The Journal of clinical investigation
Woller N,Knocke S,Mundt B,Gürlevik E,Strüver N,Kloos A,Boozari B,Schache P,Manns MP,Malek NP,Sparwasser T,Zender L,Wirth TC,Kubicka S,Kühnel F
17-5931 was used in Flow cytometry/Cell sorting to highlight viruses as attractive tools for eliciting effective antitumour responses upon DC vaccination.
Fri Jul 01 00:00:00 EDT 2011
Lineage-committed osteoclast precursors circulate in blood and settle down into bone.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Muto A,Mizoguchi T,Udagawa N,Ito S,Kawahara I,Abiko Y,Arai A,Harada S,Kobayashi Y,Nakamichi Y,Penninger JM,Noguchi T,Takahashi N
17-5931 was used in Flow cytometry/Cell sorting to demonstrate that receptor activator of NF-κB-positive cells isolated from bone marrow and peripheral blood possess characteristics of quiescent osteoclast precursors in mice.
Thu Dec 01 00:00:00 EST 2011
IL-17 produced by neutrophils regulates IFN-gamma-mediated neutrophil migration in mouse kidney ischemia-reperfusion injury.
The Journal of clinical investigation
Li L,Huang L,Vergis AL,Ye H,Bajwa A,Narayan V,Strieter RM,Rosin DL,Okusa MD
17-5931 was used in Flow cytometry/Cell sorting to study how IFN-gamma mediated neutrophil migration is mediated by upstream secretion of IL-17 in mouse kidney ischemia-reperfusion injury.
Fri Jan 01 00:00:00 EST 2010
Local mesenchymal stem/progenitor cells are a preferential target for initiation of adult soft tissue sarcomas associated with p53 and Rb deficiency.
The American journal of pathology
Choi J,Curtis SJ,Roy DM,Flesken-Nikitin A,Nikitin AY
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2010
Arhgef1 regulates alpha5beta1 integrin-mediated matrix metalloproteinase expression and is required for homeostatic lung immunity.
The American journal of pathology
Hartney JM,Brown J,Chu HW,Chang LY,Pelanda R,Torres RM
17-5931 was used in Flow cytometry/Cell sorting to study a possible regulatory role for Arhgef1 in pulmonary immunity.
Mon Mar 01 00:00:00 EST 2010
The presence of professional phagocytes dictates the number of host cells targeted for Yop translocation during infection.
Cellular microbiology
Durand EA,Maldonado-Arocho FJ,Castillo C,Walsh RL,Mecsas J
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Sun Aug 01 00:00:00 EDT 2010
CBFbeta is critical for AML1-ETO and TEL-AML1 activity.
Blood
Roudaia L,Cheney MD,Manuylova E,Chen W,Morrow M,Park S,Lee CT,Kaur P,Williams O,Bushweller JH,Speck NA
17-5931 was used in Flow cytometry/Cell sorting to validate the AML1-ETO and TEL-AML1 chimeric protein Runt domain/CBFbeta interaction as a therapeutic target in core binding factor leukemias.
Thu Mar 26 00:00:00 EDT 2009
Immune depletion with cellular mobilization imparts immunoregulation and reverses autoimmune diabetes in nonobese diabetic mice.
Diabetes
Parker MJ,Xue S,Alexander JJ,Wasserfall CH,Campbell-Thompson ML,Battaglia M,Gregori S,Mathews CE,Song S,Troutt M,Eisenbeis S,Williams J,Schatz DA,Haller MJ,Atkinson MA
17-5931 was used in Flow cytometry/Cell sorting to investigate the use of ATG and GCSF in therapies to reverse overt hyperglycaemia in a diabetic mouse model.
Thu Oct 01 00:00:00 EDT 2009
Lymphocytes in the peritoneum home to the omentum and are activated by resident dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Carlow DA,Gold MR,Ziltener HJ
17-5931 was used in Flow cytometry/Cell sorting to show that B and T lymphocytes counterflow from the peritoneal cavity to the omentum in mice where they are activated by resident dendritic cells.
Wed Jul 15 00:00:00 EDT 2009
TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.
Cellular immunology
Drage MG,Pecora ND,Hise AG,Febbraio M,Silverstein RL,Golenbock DT,Boom WH,Harding CV
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Fri Jun 12 00:00:00 EDT 2009
Some putative prebiotics increase the severity of Salmonella enterica serovar Typhimurium infection in mice.
BMC microbiology
Petersen A,Heegaard PM,Pedersen AL,Andersen JB,Sørensen RB,Frøkiaer H,Lahtinen SJ,Ouwehand AC,Poulsen M,Licht TR
17-5931 was used in Flow cytometry/Cell sorting to examine whether Salmonella infection could be prevented by administration of dietary carbohydrates with different structures and digestibility profiles.
Mon Nov 30 00:00:00 EST 2009
Listeria monocytogenes promotes tumor growth via tumor cell toll-like receptor 2 signaling.
Cancer research
Huang B,Zhao J,Shen S,Li H,He KL,Shen GX,Mayer L,Unkeless J,Li D,Yuan Y,Zhang GM,Xiong H,Feng ZH
Tue May 01 00:00:00 EDT 2007
The mouse mammary carcinoma 4T1: characterization of the cellular landscape of primary tumours and metastatic tumour foci.
International journal of experimental pathology
DuPré SA,Redelman D,Hunter KW
Published figure using Ly-6G/Ly-6C monoclonal antibody (Product # 17-5931-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2007
CARD15/NOD2 is required for Peyer's patches homeostasis in mice.
PloS one
Barreau F,Meinzer U,Chareyre F,Berrebi D,Niwa-Kawakita M,Dussaillant M,Foligne B,Ollendorff V,Heyman M,Bonacorsi S,Lesuffleur T,Sterkers G,Giovannini M,Hugot JP
17-5931 was used in Flow cytometry/Cell sorting to demonstrate that Card15/Nod2 deficiency induces abnormal development and function of Peyer's patches, characterised by exaggerated immune responses and increased permeability.
Wed Jun 13 00:00:00 EDT 2007
Hemorrhagic shock-activated neutrophils augment TLR4 signaling-induced TLR2 upregulation in alveolar macrophages: role in hemorrhage-primed lung inflammation.
American journal of physiology. Lung cellular and molecular physiology
Fan J,Li Y,Vodovotz Y,Billiar TR,Wilson MA
Sat Apr 01 00:00:00 EST 2006
CD43 deficiency has no impact in competitive in vivo assays of neutrophil or activated T cell recruitment efficiency.
Journal of immunology (Baltimore, Md. : 1950)
Carlow DA,Ziltener HJ
17-5931-82 was used in Immunohistochemistry to conclude that recruitment of neutrophils and activated T cells in these in vivo models is not influenced by CD43 expression and that if CD43 on activated T cells performs an E-SelL function in vivo, it contributes in a limited physiological context.
Wed Nov 01 00:00:00 EST 2006
-RB6-8C5-RE-AV-20170920122035.jpg?time=20220826)
-RB6-8C5-RE-AV-20170920122035.jpg?time=20220826?time=20220826 "Ly-6G/Ly-6C Antibody (17-5931-82)")
